SIMILAR PATTERNS OF AMINO ACIDS FOR 5DNU_A_BEZA319_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a80 2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE A

(Corynebacterium
sp.) 		PF00248
(Aldo_ket_red) 		4 GLN A 224
HIS A 222
ILE A 255
ILE A 258
 None
 1.06A 5dnuA-1a80A:
undetectable		 5dnuA-1a80A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jji CARBOXYLESTERASE

(Archaeoglobus
fulgidus) 		PF07859
(Abhydrolase_3) 		4 GLN A 303
ILE A 250
ILE A 288
TYR A 280
 None
 0.89A 5dnuA-1jjiA:
14.5		 5dnuA-1jjiA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kol FORMALDEHYDE
DEHYDROGENASE

(Pseudomonas
putida) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLN A 135
ILE A  45
ILE A 367
TYR A 376
 None
 1.15A 5dnuA-1kolA:
undetectable		 5dnuA-1kolA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhs PLASMA MEMBRANE
ATPASE

(Neurospora
crassa) 		PF00122
(E1-E2_ATPase)
PF00690
(Cation_ATPase_N)
PF00702
(Hydrolase) 		4 GLN A 826
ILE A 736
ILE A 809
TYR A 738
 None
 1.06A 5dnuA-1mhsA:
undetectable		 5dnuA-1mhsA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qjm LACTOFERRIN

(Equus caballus) 		PF00405
(Transferrin) 		4 GLN A  47
ILE A  46
ILE A  49
TYR A  72
 None
 1.29A 5dnuA-1qjmA:
undetectable		 5dnuA-1qjmA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rra PROTEIN
(RIBONUCLEASE)

(Rattus
norvegicus) 		PF00074
(RnaseA) 		4 GLN A  60
HIS A 105
ILE A  57
ILE A 107
 None
 1.18A 5dnuA-1rraA:
undetectable		 5dnuA-1rraA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sfj 3-DEHYDROQUINATE
DEHYDRATASE

(Staphylococcus
aureus) 		PF01487
(DHquinase_I) 		4 GLN A 122
HIS A 120
ILE A 118
ILE A  89
 None
 1.21A 5dnuA-1sfjA:
2.2		 5dnuA-1sfjA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tz6 PUTATIVE SUGAR
KINASE

(Salmonella
enterica) 		PF00294
(PfkB) 		4 HIS A 236
ILE A 229
ILE A 219
TYR A 207
 None
 1.12A 5dnuA-1tz6A:
4.1		 5dnuA-1tz6A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u7n FATTY
ACID/PHOSPHOLIPID
SYNTHESIS PROTEIN
PLSX

(Enterococcus
faecalis) 		PF02504
(FA_synthesis) 		4 GLN A  34
ILE A  55
ILE A  54
TYR A  36
 None
 1.11A 5dnuA-1u7nA:
undetectable		 5dnuA-1u7nA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vqv THIAMINE
MONOPHOSPHATE KINASE

(Aquifex
aeolicus) 		PF00586
(AIRS) 		4 HIS A  50
ILE A 126
ILE A 128
TYR A  96
 None
 1.08A 5dnuA-1vqvA:
undetectable		 5dnuA-1vqvA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wkm METHIONINE
AMINOPEPTIDASE

(Pyrococcus
furiosus) 		PF00557
(Peptidase_M24) 		4 HIS A 153
ILE A 164
ILE A 166
TYR A 176
 MN  A 296 ( 3.3A)
None
None
None
 1.03A 5dnuA-1wkmA:
undetectable		 5dnuA-1wkmA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wsj RIBONUCLEASE HI

(Escherichia
coli) 		PF00075
(RNase_H) 		4 GLN A   4
HIS A 114
ILE A  66
ILE A   7
 None
 0.92A 5dnuA-1wsjA:
undetectable		 5dnuA-1wsjA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wv3 SIMILAR TO DNA
SEGREGATION ATPASE
AND RELATED PROTEINS

(Staphylococcus
aureus) 		PF12538
(FtsK_SpoIIIE_N) 		4 GLN A  75
ILE A   5
ILE A   6
TYR A 158
 None
 1.22A 5dnuA-1wv3A:
undetectable		 5dnuA-1wv3A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b2t CHROMODOMAIN-HELICAS
E-DNA-BINDING
PROTEIN 1

(Homo sapiens) 		PF00385
(Chromo) 		4 GLN A 156
HIS A  69
ILE A 132
ILE A  70
 None
 1.22A 5dnuA-2b2tA:
undetectable		 5dnuA-2b2tA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b49 PROTEIN TYROSINE
PHOSPHATASE,
NON-RECEPTOR TYPE 3

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 GLN A 735
ILE A 715
ILE A 696
TYR A 700
 None
 1.11A 5dnuA-2b49A:
undetectable		 5dnuA-2b49A:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d2r UNDECAPRENYL
PYROPHOSPHATE
SYNTHASE

(Helicobacter
pylori) 		PF01255
(Prenyltransf) 		4 GLN A 126
ILE A  92
ILE A  42
TYR A  87
 None
 1.29A 5dnuA-2d2rA:
undetectable		 5dnuA-2d2rA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dph FORMALDEHYDE
DISMUTASE

(Pseudomonas
putida) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLN A 135
ILE A  44
ILE A 367
TYR A 376
 None
 1.17A 5dnuA-2dphA:
undetectable		 5dnuA-2dphA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eaa 7S GLOBULIN-3

(Vigna angularis) 		PF00190
(Cupin_1) 		4 GLN A 212
HIS A 217
ILE A 211
ILE A  92
 None
 1.27A 5dnuA-2eaaA:
undetectable		 5dnuA-2eaaA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2efl FORMIN-BINDING
PROTEIN 1

(Homo sapiens) 		PF00611
(FCH) 		4 GLN A  19
HIS A  17
ILE A  22
ILE A  24
 None
 1.16A 5dnuA-2eflA:
undetectable		 5dnuA-2eflA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gv9 DNA POLYMERASE

(Human
alphaherpesvirus
1) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		4 HIS A 595
ILE A 613
ILE A 609
TYR A 614
 None
 0.78A 5dnuA-2gv9A:
undetectable		 5dnuA-2gv9A:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hsj PUTATIVE PLATELET
ACTIVATING FACTOR

(Streptococcus
pneumoniae) 		PF13472
(Lipase_GDSL_2) 		4 GLN A  18
ILE A  62
ILE A  37
TYR A  65
 None
 1.21A 5dnuA-2hsjA:
3.7		 5dnuA-2hsjA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jch PENICILLIN-BINDING
PROTEIN 1B

(Streptococcus
pneumoniae) 		PF00905
(Transpeptidase)
PF00912
(Transgly) 		4 GLN A 474
ILE A 470
ILE A 472
TYR A 538
 None
 1.25A 5dnuA-2jchA:
undetectable		 5dnuA-2jchA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k49 UPF0339 PROTEIN
SO_3888

(Shewanella
oneidensis) 		PF07411
(DUF1508) 		4 GLN A  47
ILE A  43
ILE A  78
TYR A   5
 None
 0.99A 5dnuA-2k49A:
undetectable		 5dnuA-2k49A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kdp HISTONE DEACETYLASE
COMPLEX SUBUNIT
SAP30

(Homo sapiens) 		PF13866
(zf-SAP30) 		4 GLN A 120
HIS A 115
ILE A  89
ILE A  93
 None
ZN  A   1 ( 2.8A)
None
None
 1.14A 5dnuA-2kdpA:
undetectable		 5dnuA-2kdpA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nyg YOKD PROTEIN

(Bacillus
subtilis) 		PF02522
(Antibiotic_NAT) 		4 GLN A  54
ILE A  53
ILE A  66
TYR A 122
 None
 0.83A 5dnuA-2nygA:
undetectable		 5dnuA-2nygA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xpi ANAPHASE-PROMOTING
COMPLEX SUBUNIT CUT9

(Schizosaccharomyces
pombe) 		PF12895
(ANAPC3)
PF13181
(TPR_8)
PF13424
(TPR_12) 		4 GLN A 499
HIS A 497
ILE A 495
TYR A 526
 None
 1.22A 5dnuA-2xpiA:
undetectable		 5dnuA-2xpiA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yeq ALKALINE PHOSPHATASE
D

(Bacillus
subtilis) 		PF09423
(PhoD)
PF16655
(PhoD_N) 		4 GLN A 125
HIS A 129
ILE A 410
TYR A 135
 None
 1.24A 5dnuA-2yeqA:
undetectable		 5dnuA-2yeqA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 GLN A 248
ILE A 360
ILE A 373
TYR A 356
 None
 1.27A 5dnuA-2zu6A:
undetectable		 5dnuA-2zu6A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aly PUTATIVE
UNCHARACTERIZED
PROTEIN ST0753

(Sulfurisphaera
tokodaii) 		PF13456
(RVT_3) 		4 GLN A  83
ILE A  95
ILE A  96
TYR A  53
 None
 1.16A 5dnuA-3alyA:
undetectable		 5dnuA-3alyA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3axx 458AA LONG
HYPOTHETICAL
ENDO-1,4-BETA-GLUCAN
ASE

(Pyrococcus
horikoshii) 		PF00150
(Cellulase) 		4 HIS A  76
ILE A 119
ILE A 117
TYR A 121
 None
PO4  A 462 (-4.9A)
None
PO4  A 462 ( 4.8A)
 0.98A 5dnuA-3axxA:
undetectable		 5dnuA-3axxA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli) 		PF07517
(SecA_DEAD) 		4 GLN A 378
ILE A 404
ILE A 216
TYR A 405
 None
 1.29A 5dnuA-3bxzA:
undetectable		 5dnuA-3bxzA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fbg PUTATIVE ARGINATE
LYASE

(Staphylococcus
haemolyticus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLN A 101
ILE A 103
ILE A  33
TYR A  87
 None
 1.18A 5dnuA-3fbgA:
undetectable		 5dnuA-3fbgA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1j MITOCHONDRIAL
UBIQUINOL-CYTOCHROME
C REDUCTASE
UBIQUINONE-BINDING
PROTEIN QP-C

(Gallus gallus) 		PF02939
(UcrQ) 		4 HIS G  12
ILE G  14
ILE G  13
TYR G  16
 None
 1.27A 5dnuA-3h1jG:
undetectable		 5dnuA-3h1jG:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hiu UNCHARACTERIZED
PROTEIN

(Xanthomonas
campestris) 		PF05974
(DUF892) 		4 GLN A  55
ILE A 136
ILE A 132
TYR A 114
 NA  A   1 (-3.2A)
None
None
None
 1.25A 5dnuA-3hiuA:
undetectable		 5dnuA-3hiuA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i1a SPECTINOMYCIN
PHOSPHOTRANSFERASE

(Legionella
pneumophila) 		PF01636
(APH) 		4 GLN A  90
ILE A  97
ILE A  98
TYR A  19
 None
 1.28A 5dnuA-3i1aA:
undetectable		 5dnuA-3i1aA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3if6 OXA-46 OXACILLINASE

(Pseudomonas
aeruginosa) 		PF00905
(Transpeptidase) 		4 GLN C 171
HIS C 169
ILE C 166
TYR C 146
 None
 1.12A 5dnuA-3if6C:
undetectable		 5dnuA-3if6C:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j1e CHAPERONIN BETA
SUBUNIT

(Acidianus
tengchongensis) 		PF00118
(Cpn60_TCP1) 		4 GLN A 191
ILE A 379
ILE A 381
TYR A 224
 None
 1.13A 5dnuA-3j1eA:
undetectable		 5dnuA-3j1eA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jrq PUTATIVE
UNCHARACTERIZED
PROTEIN AT5G46790

(Arabidopsis
thaliana) 		PF10604
(Polyketide_cyc2) 		4 GLN B  83
HIS B  87
ILE B  89
ILE B 111
 None
 1.09A 5dnuA-3jrqB:
undetectable		 5dnuA-3jrqB:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kgy BIFUNCTIONAL
DEAMINASE-REDUCTASE
DOMAIN PROTEIN

(Chloroflexus
aurantiacus) 		PF01872
(RibD_C) 		4 HIS A  80
ILE A 148
ILE A 146
TYR A 158
 None
 1.23A 5dnuA-3kgyA:
undetectable		 5dnuA-3kgyA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ktc XYLOSE ISOMERASE

(Pectobacterium
atrosepticum) 		PF01261
(AP_endonuc_2) 		4 GLN A 305
ILE A 301
ILE A 319
TYR A 256
 UNL  A 338 ( 3.8A)
UNL  A 338 ( 3.7A)
None
None
 0.96A 5dnuA-3ktcA:
undetectable		 5dnuA-3ktcA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kya PUTATIVE PHOSPHATASE

(Bacteroides
thetaiotaomicron) 		PF01833
(TIG) 		4 GLN A 187
ILE A 178
ILE A 213
TYR A 180
 None
 1.10A 5dnuA-3kyaA:
undetectable		 5dnuA-3kyaA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l6d PUTATIVE
OXIDOREDUCTASE

(Pseudomonas
putida) 		PF03446
(NAD_binding_2) 		4 HIS A 140
ILE A 127
ILE A 142
TYR A 100
 None
 1.04A 5dnuA-3l6dA:
undetectable		 5dnuA-3l6dA:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r0p L-PSP PUTATIVE
ENDORIBONUCLEASE

(uncultured
organism) 		PF01042
(Ribonuc_L-PSP) 		4 GLN A  52
HIS A  54
ILE A 119
ILE A  89
 None
 1.24A 5dnuA-3r0pA:
undetectable		 5dnuA-3r0pA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ruc WBGU

(Plesiomonas
shigelloides) 		PF01370
(Epimerase) 		4 GLN A  98
ILE A  28
ILE A 243
TYR A 193
 None
NAD  A 343 (-3.8A)
None
NAD  A 343 ( 4.6A)
 1.27A 5dnuA-3rucA:
4.8		 5dnuA-3rucA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w6m 458AA LONG
HYPOTHETICAL
ENDO-1,4-BETA-GLUCAN
ASE

(Pyrococcus
horikoshii) 		PF00150
(Cellulase) 		4 HIS A  76
ILE A 119
ILE A 117
TYR A 121
 None
 0.99A 5dnuA-3w6mA:
undetectable		 5dnuA-3w6mA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wnp CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE

(Bacillus
circulans) 		PF13199
(Glyco_hydro_66)
PF16990
(CBM_35) 		4 GLN A 309
HIS A 306
ILE A 236
TYR A 237
 None
 0.99A 5dnuA-3wnpA:
undetectable		 5dnuA-3wnpA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cz1 KYNURENINE
FORMAMIDASE

(Bacillus
anthracis) 		PF04199
(Cyclase) 		4 HIS A  60
ILE A  55
ILE A 171
TYR A  76
 VNJ  A 501 (-4.2A)
None
None
None
 1.00A 5dnuA-4cz1A:
undetectable		 5dnuA-4cz1A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dna PROBABLE GLUTATHIONE
REDUCTASE

(Sinorhizobium
meliloti) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 GLN A 235
HIS A 252
ILE A 233
ILE A 199
 None
 1.20A 5dnuA-4dnaA:
undetectable		 5dnuA-4dnaA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dr9 PEPTIDE DEFORMYLASE

(Synechococcus
elongatus) 		PF01327
(Pep_deformylase) 		4 GLN A 150
HIS A 151
ILE A 149
ILE A  74
 None
ZN  A 201 ( 3.3A)
None
None
 1.16A 5dnuA-4dr9A:
undetectable		 5dnuA-4dr9A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ebg UNCHARACTERIZED
PROTEIN

(Staphylococcus
aureus) 		PF14729
(DUF4467) 		4 GLN A  36
ILE A  72
ILE A  29
TYR A  88
 None
 1.28A 5dnuA-4ebgA:
undetectable		 5dnuA-4ebgA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f6c AUSA REDUCTASE
DOMAIN PROTEIN

(Staphylococcus
aureus) 		PF07993
(NAD_binding_4) 		4 GLN A2161
HIS A2163
ILE A2157
ILE A2129
 None
 1.24A 5dnuA-4f6cA:
3.9		 5dnuA-4f6cA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gq2 NUCLEOPORIN NUP120

(Schizosaccharomyces
pombe) 		PF11715
(Nup160) 		4 GLN M 207
ILE M 196
ILE M 195
TYR M 205
 None
 1.28A 5dnuA-4gq2M:
undetectable		 5dnuA-4gq2M:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i3h TOPOISOMERASE IV
SUBUNIT B, DNA
TOPOISOMERASE 4
SUBUNIT A CHIMERA

(Streptococcus
pneumoniae) 		PF00204
(DNA_gyraseB)
PF00521
(DNA_topoisoIV)
PF00986
(DNA_gyraseB_C)
PF01751
(Toprim)
PF02518
(HATPase_c) 		4 HIS A 534
ILE A 502
ILE A 501
TYR A 430
 None
 1.20A 5dnuA-4i3hA:
2.5		 5dnuA-4i3hA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i8v CYTOCHROME P450 1A1

(Homo sapiens) 		PF00067
(p450) 		4 GLN A 290
HIS A 288
ILE A 286
TYR A 270
 None
 1.18A 5dnuA-4i8vA:
undetectable		 5dnuA-4i8vA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i8v CYTOCHROME P450 1A1

(Homo sapiens) 		PF00067
(p450) 		4 GLN A 290
ILE A 286
ILE A 307
TYR A 270
 None
 1.25A 5dnuA-4i8vA:
undetectable		 5dnuA-4i8vA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jlw GLUTATHIONE-INDEPEND
ENT FORMALDEHYDE
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLN A 136
ILE A  46
ILE A 368
TYR A 377
 None
 1.17A 5dnuA-4jlwA:
undetectable		 5dnuA-4jlwA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4juo DNA TOPOISOMERASE 4
SUBUNIT B

(Streptococcus
pneumoniae) 		PF00204
(DNA_gyraseB)
PF00986
(DNA_gyraseB_C)
PF01751
(Toprim)
PF02518
(HATPase_c) 		4 HIS C 534
ILE C 502
ILE C 501
TYR C 430
 None
 1.26A 5dnuA-4juoC:
3.6		 5dnuA-4juoC:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nsy LYSYL ENDOPEPTIDASE

(Lysobacter
enzymogenes) 		PF13365
(Trypsin_2) 		4 HIS A 159
ILE A 198
ILE A 147
TYR A 227
 None
 1.25A 5dnuA-4nsyA:
undetectable		 5dnuA-4nsyA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pdd TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Polaromonas sp.
JS666) 		PF03480
(DctP) 		4 GLN A 329
ILE A 325
ILE A 110
TYR A 313
 None
None
None
MLA  A 404 (-4.4A)
 1.25A 5dnuA-4pddA:
undetectable		 5dnuA-4pddA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6j LMO0131 PROTEIN

(Listeria
monocytogenes) 		PF00563
(EAL) 		4 GLN A  77
ILE A  87
ILE A  89
TYR A  21
 None
 1.03A 5dnuA-4q6jA:
undetectable		 5dnuA-4q6jA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1

(Pisum sativum) 		PF00223
(PsaA_PsaB) 		4 HIS A 343
ILE A 327
ILE A 330
TYR A 317
 LHG  A7003 ( 4.0A)
CLA  A1119 ( 4.5A)
CLA  A1119 (-4.3A)
CLA  A1119 (-4.6A)
 1.17A 5dnuA-4rkuA:
undetectable		 5dnuA-4rkuA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ru5 TAILSPIKE GP27

(Pseudomonas
phage phi297) 		no annotation 4 GLN A 655
ILE A 676
ILE A 718
TYR A 680
 None
 1.12A 5dnuA-4ru5A:
undetectable		 5dnuA-4ru5A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uzy FLAGELLAR ASSOCIATED
PROTEIN

(Chlamydomonas
reinhardtii) 		PF12895
(ANAPC3)
PF13174
(TPR_6) 		4 GLN A  37
HIS A  35
ILE A  33
TYR A  57
 None
 1.21A 5dnuA-4uzyA:
undetectable		 5dnuA-4uzyA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wxl PEPTIDE DEFORMYLASE

(Haemophilus
influenzae) 		PF01327
(Pep_deformylase) 		4 GLN A 132
HIS A 133
ILE A 131
ILE A  59
 None
NI  A 201 ( 3.3A)
None
None
 1.18A 5dnuA-4wxlA:
undetectable		 5dnuA-4wxlA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y2w ALANINE RACEMASE 1

(Caldanaerobacter
subterraneus) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 GLN A 104
HIS A 129
ILE A 130
TYR A 111
 None
 1.23A 5dnuA-4y2wA:
undetectable		 5dnuA-4y2wA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yci BONE MORPHOGENETIC
PROTEIN 9 GROWTH
FACTOR DOMAIN

(Mus musculus) 		PF00688
(TGFb_propeptide) 		4 GLN A 121
HIS A 119
ILE A 122
ILE A  85
 None
ZN  A 303 (-2.9A)
None
None
 1.10A 5dnuA-4yciA:
undetectable		 5dnuA-4yciA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yep LAMININ SUBUNIT
ALPHA-2

(Homo sapiens) 		PF00052
(Laminin_B) 		4 GLN A1273
ILE A1341
ILE A1339
TYR A1255
 EDO  A1401 (-3.1A)
None
None
None
 0.99A 5dnuA-4yepA:
undetectable		 5dnuA-4yepA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yeq LAMININ SUBUNIT
ALPHA-2

(Homo sapiens) 		PF00052
(Laminin_B) 		4 GLN U  98
ILE U 166
ILE U 164
TYR U  80
 None
 0.97A 5dnuA-4yeqU:
undetectable		 5dnuA-4yeqU:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yf6 BETA-CARBONIC
ANHYDRASE 1

(Mycobacterium
tuberculosis) 		PF00484
(Pro_CA) 		4 GLN A  75
HIS A  54
ILE A  83
ILE A  30
 None
 1.17A 5dnuA-4yf6A:
2.0		 5dnuA-4yf6A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z3o DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE

(Streptococcus
pneumoniae) 		PF00521
(DNA_topoisoIV)
PF00986
(DNA_gyraseB_C)
PF01751
(Toprim) 		4 HIS A 534
ILE A 502
ILE A 501
TYR A 430
 None
 1.24A 5dnuA-4z3oA:
3.9		 5dnuA-4z3oA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah0 LIPASE

(Pelosinus
fermentans) 		no annotation 4 GLN A 269
ILE A 272
ILE A 358
TYR A 274
 None
 1.11A 5dnuA-5ah0A:
12.8		 5dnuA-5ah0A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b37 TRYPTOPHAN
DEHYDROGENASE

(Nostoc
punctiforme) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 GLN A 306
HIS A 308
ILE A 289
ILE A 145
 None
 1.03A 5dnuA-5b37A:
undetectable		 5dnuA-5b37A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dgq PUTATIVE
ENDOGLUCANASE-RELATE
D PROTEIN

(Photobacterium
profundum) 		PF00759
(Glyco_hydro_9) 		4 HIS A 482
ILE A 568
ILE A 458
TYR A 564
 None
 1.25A 5dnuA-5dgqA:
undetectable		 5dnuA-5dgqA:
18.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dnw SHKAI2IB

(Striga
hermonthica) 		PF12697
(Abhydrolase_6) 		5 GLN A  71
HIS A  75
ILE A 103
ILE A 107
TYR A 201
 None
 0.09A 5dnuA-5dnwA:
50.1		 5dnuA-5dnwA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5erd DESMOGLEIN-2

(Homo sapiens) 		PF00028
(Cadherin) 		4 GLN A 365
HIS A 338
ILE A 432
TYR A 379
 None
 1.19A 5dnuA-5erdA:
undetectable		 5dnuA-5erdA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j46 PEPTIDE DEFORMYLASE

(Burkholderia
multivorans) 		PF01327
(Pep_deformylase) 		4 GLN A 147
HIS A 148
ILE A 146
ILE A  73
 None
ZN  A 200 (-3.3A)
None
None
 1.15A 5dnuA-5j46A:
undetectable		 5dnuA-5j46A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jvh 50S RIBOSOMAL
PROTEIN L13

(Deinococcus
radiodurans) 		PF00572
(Ribosomal_L13) 		4 GLN G 140
HIS G 145
ILE G  75
ILE G  62
 U  X 566 ( 4.1A)
None
None
None
 1.26A 5dnuA-5jvhG:
undetectable		 5dnuA-5jvhG:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k34 ANKYRIN-REPEAT
PROTEIN B

(Legionella
pneumophila) 		no annotation 4 GLN A 138
ILE A 152
ILE A 156
TYR A 107
 None
 1.18A 5dnuA-5k34A:
undetectable		 5dnuA-5k34A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k35 ANKYRIN-REPEAT
PROTEIN B

(Legionella
pneumophila) 		PF12937
(F-box-like) 		4 GLN A 138
ILE A 152
ILE A 156
TYR A 107
 None
 1.21A 5dnuA-5k35A:
undetectable		 5dnuA-5k35A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275

(Mycolicibacterium
smegmatis) 		PF00936
(BMC) 		4 GLN A  37
HIS A  77
ILE A  38
ILE A  64
 None
 1.14A 5dnuA-5l39A:
undetectable		 5dnuA-5l39A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mmx CSPYL1_ABA

(Citrus sinensis) 		no annotation 4 GLN B  85
HIS B  89
ILE B  91
ILE B 113
 None
 1.28A 5dnuA-5mmxB:
undetectable		 5dnuA-5mmxB:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mpd 26S PROTEASOME
REGULATORY SUBUNIT
RPN9

(Saccharomyces
cerevisiae) 		PF01399
(PCI) 		4 GLN O 211
ILE O 242
ILE O 238
TYR O 248
 None
 0.78A 5dnuA-5mpdO:
undetectable		 5dnuA-5mpdO:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nvr TELOMERE LENGTH
REGULATOR PROTEIN
RIF1

(Saccharomyces
cerevisiae) 		PF12231
(Rif1_N) 		4 GLN A 355
ILE A 351
ILE A 350
TYR A 301
 None
 1.24A 5dnuA-5nvrA:
undetectable		 5dnuA-5nvrA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t8v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		PF12765
(Cohesin_HEAT)
PF12830
(Nipped-B_C) 		4 GLN A1639
ILE A1663
ILE A1591
TYR A1659
 None
 1.25A 5dnuA-5t8vA:
undetectable		 5dnuA-5t8vA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uak CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR

(Homo sapiens) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane)
PF14396
(CFTR_R) 		4 GLN A1352
HIS A1350
ILE A1384
ILE A1383
 None
 1.24A 5dnuA-5uakA:
undetectable		 5dnuA-5uakA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v2m MEVALONATE
DIPHOSPHATE
DECARBOXYLASE

(Enterococcus
faecalis) 		no annotation 4 GLN A 218
HIS A 220
ILE A 234
ILE A  15
 None
 0.84A 5dnuA-5v2mA:
undetectable		 5dnuA-5v2mA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w1u CARBOXYLIC ESTER
HYDROLASE

(Culex
quinquefasciatus) 		PF00135
(COesterase) 		4 GLN A 198
HIS A 200
ILE A 202
ILE A 298
 None
 1.22A 5dnuA-5w1uA:
10.5		 5dnuA-5w1uA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w2b NUCLEOPROTEIN

(Reston
ebolavirus) 		no annotation 4 GLN A 736
HIS A 737
ILE A 715
ILE A 713
 None
 1.11A 5dnuA-5w2bA:
undetectable		 5dnuA-5w2bA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wqw N-ACETYLGLUCOSAMINID
ASE

(Clostridium
perfringens) 		PF01832
(Glucosaminidase) 		4 GLN A 968
ILE A1104
ILE A1107
TYR A1100
 EDO  A1206 (-2.8A)
None
None
EDO  A1206 (-4.2A)
 1.11A 5dnuA-5wqwA:
undetectable		 5dnuA-5wqwA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x5g BETA-LACTAMASE

(Serratia
marcescens) 		PF13354
(Beta-lactamase2) 		4 HIS A 223
ILE A 244
ILE A 245
TYR A 184
 None
 1.19A 5dnuA-5x5gA:
undetectable		 5dnuA-5x5gA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x7h CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE

(Paenibacillus
sp. 598K) 		PF13199
(Glyco_hydro_66)
PF16990
(CBM_35) 		4 GLN A 310
HIS A 307
ILE A 237
TYR A 238
 None
 1.01A 5dnuA-5x7hA:
undetectable		 5dnuA-5x7hA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y1g NAD DEPENDENT
EPIMERASE/DEHYDRATAS
E FAMILY

(uncultured
archaeon
MedDCM-OCT-S05-C57) 		no annotation 4 GLN A 104
HIS A   0
ILE A  63
ILE A   2
 None
 1.18A 5dnuA-5y1gA:
4.6		 5dnuA-5y1gA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6an5 ABC TRANSPORTER

(Aquifex
aeolicus) 		no annotation 4 HIS A 157
ILE A 118
ILE A 154
TYR A 105
 None
 1.20A 5dnuA-6an5A:
undetectable		 5dnuA-6an5A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6azh TETR FAMILY
TRANSCRIPTIONAL
REGULATOR

(Clostridium
perfringens) 		no annotation 4 GLN A  87
ILE A 126
ILE A 129
TYR A 122
 None
 1.20A 5dnuA-6azhA:
undetectable		 5dnuA-6azhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bhu MULTIDRUG
RESISTANCE-ASSOCIATE
D PROTEIN 1

(Bos taurus) 		no annotation 4 HIS A1485
ILE A1490
ILE A1324
TYR A1493
 ATP  A1602 (-4.4A)
None
None
None
 1.17A 5dnuA-6bhuA:
undetectable		 5dnuA-6bhuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dk2 -

(-) 		no annotation 4 GLN A 373
HIS A 376
ILE A 369
ILE A 309
 None
 1.09A 5dnuA-6dk2A:
undetectable		 5dnuA-6dk2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj PROTEIN CFT1

(Saccharomyces
cerevisiae) 		no annotation 4 GLN A 740
ILE A 742
ILE A 704
TYR A 770
 None
 1.25A 5dnuA-6eojA:
undetectable		 5dnuA-6eojA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6evg MULTI-COPPER OXIDASE
CUEO

(Ochrobactrum) 		no annotation 4 GLN A 176
HIS A 131
ILE A 146
TYR A  63
 None
 1.26A 5dnuA-6evgA:
undetectable		 5dnuA-6evgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f1v CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1

(Homo sapiens) 		no annotation 4 GLN f 813
ILE f 816
ILE f 820
TYR f 788
 None
 1.16A 5dnuA-6f1vf:
undetectable		 5dnuA-6f1vf:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f1y CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1,DYNEIN
HEAVY CHAIN

(Homo sapiens) 		no annotation 4 GLN f 813
ILE f 816
ILE f 820
TYR f 788
 None
 1.16A 5dnuA-6f1yf:
undetectable		 5dnuA-6f1yf:
undetectable