SIMILAR PATTERNS OF AMINO ACIDS FOR 5D4N_A_ACTA202

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iv0 HYPOTHETICAL PROTEIN

(Thermus
thermophilus) 		PF03652
(RuvX) 		4 VAL A  86
GLY A  85
ARG A  82
VAL A  88
 None
 1.47A 5d4nA-1iv0A:
undetectable
5d4nB-1iv0A:
undetectable		 5d4nA-1iv0A:
24.32
5d4nB-1iv0A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ka9 IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE
IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE

(Thermus
thermophilus;
Thermus
thermophilus) 		PF00977
(His_biosynth)
PF00117
(GATase) 		4 VAL F 195
GLY F 196
ARG H 115
VAL F 199
 None
 1.40A 5d4nA-1ka9F:
0.0
5d4nB-1ka9F:
0.0		 5d4nA-1ka9F:
17.84
5d4nB-1ka9F:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sxj ACTIVATOR 1 95 KDA
SUBUNIT

(Saccharomyces
cerevisiae) 		PF00004
(AAA)
PF08519
(RFC1) 		4 VAL A 437
GLY A 436
ARG A 383
VAL A 426
 None
 1.39A 5d4nA-1sxjA:
0.0
5d4nB-1sxjA:
0.0		 5d4nA-1sxjA:
12.45
5d4nB-1sxjA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x7h PUTATIVE KETOACYL
REDUCTASE

(Streptomyces
coelicolor) 		PF00106
(adh_short) 		4 VAL A 221
GLY A 224
ARG A 225
VAL A 227
 None
 1.36A 5d4nA-1x7hA:
0.0
5d4nB-1x7hA:
0.0		 5d4nA-1x7hA:
20.16
5d4nB-1x7hA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dst HYPOTHETICAL PROTEIN
TTHA1544

(Thermus
thermophilus) 		no annotation 4 VAL A 110
GLY A 109
ARG A  87
VAL A 112
 None
 1.36A 5d4nA-2dstA:
0.0
5d4nB-2dstA:
undetectable		 5d4nA-2dstA:
26.67
5d4nB-2dstA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g85 CHORISMATE SYNTHASE

(Mycobacterium
tuberculosis) 		PF01264
(Chorismate_synt) 		4 VAL A 145
GLY A 148
ARG A 152
VAL A 352
 None
 1.02A 5d4nA-2g85A:
0.0
5d4nB-2g85A:
0.0		 5d4nA-2g85A:
14.70
5d4nB-2g85A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gep SULFITE REDUCTASE
HEMOPROTEIN

(Escherichia
coli) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 VAL A 253
GLY A 254
ARG A 269
VAL A 316
 None
 1.42A 5d4nA-2gepA:
1.3
5d4nB-2gepA:
1.0		 5d4nA-2gepA:
14.01
5d4nB-2gepA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ggj N-ACYLAMINO ACID
RACEMASE

(Deinococcus
radiodurans) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 VAL A  51
GLY A  50
ARG A 120
VAL A 356
 None
 1.20A 5d4nA-2ggjA:
0.1
5d4nB-2ggjA:
0.0		 5d4nA-2ggjA:
12.80
5d4nB-2ggjA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gzl 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE

(Escherichia
coli) 		PF02542
(YgbB) 		4 VAL A  23
GLY A  22
ARG A  74
VAL A 114
 None
 1.28A 5d4nA-2gzlA:
undetectable
5d4nB-2gzlA:
undetectable		 5d4nA-2gzlA:
21.30
5d4nB-2gzlA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nwb CONSERVED DOMAIN
PROTEIN

(Shewanella
oneidensis) 		PF08933
(DUF1864) 		4 VAL A 226
GLY A 227
ARG A 225
VAL A 230
 None
 1.34A 5d4nA-2nwbA:
undetectable
5d4nB-2nwbA:
undetectable		 5d4nA-2nwbA:
14.44
5d4nB-2nwbA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qq6 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN

(Rubrobacter
xylanophilus) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 VAL A 205
GLY A 206
ARG A 202
VAL A 211
 None
 1.33A 5d4nA-2qq6A:
undetectable
5d4nB-2qq6A:
undetectable		 5d4nA-2qq6A:
13.93
5d4nB-2qq6A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9z GLUTATHIONE AMIDE
REDUCTASE

(Marichromatium
gracile) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 VAL A 421
GLY A 424
ARG A 399
VAL A 401
 None
 1.49A 5d4nA-2r9zA:
undetectable
5d4nB-2r9zA:
undetectable		 5d4nA-2r9zA:
13.29
5d4nB-2r9zA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3n CARBONIC ANHYDRASE 2

(Cryptococcus
neoformans) 		PF00484
(Pro_CA) 		4 VAL A 122
GLY A  67
ARG A  90
VAL A  73
 None
 1.31A 5d4nA-2w3nA:
undetectable
5d4nB-2w3nA:
undetectable		 5d4nA-2w3nA:
22.59
5d4nB-2w3nA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y7r LYSR-TYPE REGULATORY
PROTEIN

(Burkholderia
sp. DNT) 		PF03466
(LysR_substrate) 		4 VAL A 199
GLY A 198
ARG A 220
VAL A 209
 None
 1.25A 5d4nA-2y7rA:
undetectable
5d4nB-2y7rA:
undetectable		 5d4nA-2y7rA:
17.29
5d4nB-2y7rA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c3p METHYLTRANSFERASE

(Geobacter
sulfurreducens) 		PF01596
(Methyltransf_3) 		4 VAL A 198
GLY A 201
ARG A 162
VAL A   5
 None
None
None
EDO  A 213 (-4.2A)
 1.49A 5d4nA-3c3pA:
undetectable
5d4nB-3c3pA:
undetectable		 5d4nA-3c3pA:
18.27
5d4nB-3c3pA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cvj PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE

(Bacillus
halodurans) 		PF13580
(SIS_2) 		4 VAL A  38
GLY A  42
ARG A  43
VAL A  69
 None
 1.40A 5d4nA-3cvjA:
undetectable
5d4nB-3cvjA:
undetectable		 5d4nA-3cvjA:
18.53
5d4nB-3cvjA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e3u PEPTIDE DEFORMYLASE

(Mycobacterium
tuberculosis) 		PF01327
(Pep_deformylase) 		4 VAL A  81
GLY A  80
ARG A  77
VAL A 134
 None
 1.26A 5d4nA-3e3uA:
undetectable
5d4nB-3e3uA:
undetectable		 5d4nA-3e3uA:
18.36
5d4nB-3e3uA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eck PROTEIN
(HOMOPROTOCATECHUATE
2,3-DIOXYGENASE)

(Brevibacterium
fuscum) 		PF00903
(Glyoxalase) 		4 VAL A 159
GLY A 207
ARG A 324
VAL A 163
 None
 1.29A 5d4nA-3eckA:
undetectable
5d4nB-3eckA:
undetectable		 5d4nA-3eckA:
13.77
5d4nB-3eckA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE

(Yersinia pestis) 		PF02542
(YgbB) 		4 VAL A  25
GLY A  24
ARG A  76
VAL A 116
 None
 1.26A 5d4nA-3f6mA:
undetectable
5d4nB-3f6mA:
undetectable		 5d4nA-3f6mA:
24.40
5d4nB-3f6mA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ftj MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB

(Aggregatibacter
actinomycetemcomitans) 		PF12704
(MacB_PCD) 		4 VAL A 413
GLY A 444
ARG A 398
VAL A 411
 None
 1.45A 5d4nA-3ftjA:
4.1
5d4nB-3ftjA:
4.3		 5d4nA-3ftjA:
18.01
5d4nB-3ftjA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g7z CYTOTOXIC PROTEIN
CCDB

(Escherichia
coli) 		PF01845
(CcdB) 		4 VAL A  73
GLY A  29
ARG A  30
VAL A  71
 None
 1.42A 5d4nA-3g7zA:
undetectable
5d4nB-3g7zA:
undetectable		 5d4nA-3g7zA:
22.41
5d4nB-3g7zA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gce FERREDOXIN COMPONENT
OF CARBAZOLE
1,9A-DIOXYGENASE

(Nocardioides
aromaticivorans) 		PF00355
(Rieske) 		4 VAL A  76
GLY A  77
ARG A  78
VAL A  62
 None
FES  A 201 (-3.9A)
None
None
 1.42A 5d4nA-3gceA:
undetectable
5d4nB-3gceA:
undetectable		 5d4nA-3gceA:
21.37
5d4nB-3gceA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6s SUBTILISIN-LIKE
PROTEASE

(Solanum
lycopersicum) 		PF00082
(Peptidase_S8) 		4 VAL A 278
GLY A 277
ARG A 165
VAL A 138
 None
 1.22A 5d4nA-3i6sA:
undetectable
5d4nB-3i6sA:
1.8		 5d4nA-3i6sA:
10.17
5d4nB-3i6sA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF08938
(HBS1_N) 		4 VAL 1 531
GLY 1 530
ARG 1 588
VAL 1 405
 None
 1.23A 5d4nA-3izq1:
undetectable
5d4nB-3izq1:
undetectable		 5d4nA-3izq1:
11.78
5d4nB-3izq1:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42

(Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 VAL A  68
GLY A  67
ARG A  70
VAL A  75
 None
None
C  N  14 ( 3.8A)
C  N  14 ( 4.4A)
 1.38A 5d4nA-3jb9A:
4.6
5d4nB-3jb9A:
4.9		 5d4nA-3jb9A:
4.19
5d4nB-3jb9A:
4.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jxo TRKA-N DOMAIN
PROTEIN

(Thermotoga sp.
RQ2) 		PF02080
(TrkA_C) 		4 VAL A 183
GLY A 181
ARG A 180
VAL A 185
 None
 1.38A 5d4nA-3jxoA:
2.0
5d4nB-3jxoA:
2.4		 5d4nA-3jxoA:
26.55
5d4nB-3jxoA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lg5 EPI-ISOZIZAENE
SYNTHASE

(Streptomyces
coelicolor) 		no annotation 4 VAL A 276
GLY A 274
ARG A 277
VAL A 280
 None
 1.34A 5d4nA-3lg5A:
undetectable
5d4nB-3lg5A:
undetectable		 5d4nA-3lg5A:
14.40
5d4nB-3lg5A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lnc GUANYLATE KINASE

(Anaplasma
phagocytophilum) 		PF00625
(Guanylate_kin) 		4 VAL A  94
GLY A   6
ARG A 194
VAL A 120
 None
 1.09A 5d4nA-3lncA:
undetectable
5d4nB-3lncA:
undetectable		 5d4nA-3lncA:
20.35
5d4nB-3lncA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG

(Mus musculus) 		PF14674
(FANCI_S1-cap)
PF14675
(FANCI_S1)
PF14676
(FANCI_S2)
PF14677
(FANCI_S3)
PF14678
(FANCI_S4)
PF14679
(FANCI_HD1)
PF14680
(FANCI_HD2) 		4 VAL A  43
GLY A  44
ARG A  41
VAL A  85
 None
 1.36A 5d4nA-3s51A:
undetectable
5d4nB-3s51A:
undetectable		 5d4nA-3s51A:
6.00
5d4nB-3s51A:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3usc HYDROGENASE-1 LARGE
CHAIN

(Escherichia
coli) 		PF00374
(NiFeSe_Hases) 		4 VAL L 502
GLY L 501
ARG L 500
VAL L 340
 None
 1.45A 5d4nA-3uscL:
undetectable
5d4nB-3uscL:
undetectable		 5d4nA-3uscL:
11.13
5d4nB-3uscL:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vnp HYPOTHETICAL
CONSERVED PROTEIN

(Geobacillus
kaustophilus) 		PF00132
(Hexapep) 		4 VAL A  55
GLY A  76
ARG A  54
VAL A 159
 None
 1.45A 5d4nA-3vnpA:
undetectable
5d4nB-3vnpA:
undetectable		 5d4nA-3vnpA:
20.11
5d4nB-3vnpA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x0u UNCHARACTERIZED
PROTEIN

(Vibrio
parahaemolyticus) 		PF03945
(Endotoxin_N) 		4 VAL A 388
GLY A 389
ARG A 375
VAL A 377
 None
 1.46A 5d4nA-3x0uA:
undetectable
5d4nB-3x0uA:
undetectable		 5d4nA-3x0uA:
13.30
5d4nB-3x0uA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a6u OMEGA TRANSAMINASE

(Chromobacterium
violaceum) 		PF00202
(Aminotran_3) 		4 VAL A 379
GLY A 375
ARG A 374
VAL A 423
 None
 1.07A 5d4nA-4a6uA:
0.0
5d4nB-4a6uA:
0.6		 5d4nA-4a6uA:
16.55
5d4nB-4a6uA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bed HEMOCYANIN KLH1

(Megathura
crenulata) 		PF00264
(Tyrosinase)
PF14830
(Haemocyan_bet_s) 		4 VAL A 503
GLY A 504
ARG A 505
VAL A 498
 None
 1.31A 5d4nA-4bedA:
undetectable
5d4nB-4bedA:
undetectable		 5d4nA-4bedA:
5.59
5d4nB-4bedA:
5.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g38 SULFITE REDUCTASE
[NADPH] HEMOPROTEIN
BETA-COMPONENT

(Escherichia
coli) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 VAL A 253
GLY A 254
ARG A 269
VAL A 316
 None
 1.42A 5d4nA-4g38A:
undetectable
5d4nB-4g38A:
3.0		 5d4nA-4g38A:
12.34
5d4nB-4g38A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jpb CHEMOTAXIS PROTEIN
CHEA

(Thermotoga
maritima) 		PF01584
(CheW) 		4 VAL A 617
GLY A 618
ARG A 616
VAL A 615
 None
 1.41A 5d4nA-4jpbA:
undetectable
5d4nB-4jpbA:
undetectable		 5d4nA-4jpbA:
15.38
5d4nB-4jpbA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pk1 CHIMERA PROTEIN OF
OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTORS BAMA AND
BAMB

(Escherichia
coli) 		PF07244
(POTRA)
PF13360
(PQQ_2) 		4 VAL A1115
GLY A1114
ARG A1154
VAL A1117
 None
 1.19A 5d4nA-4pk1A:
undetectable
5d4nB-4pk1A:
undetectable		 5d4nA-4pk1A:
10.20
5d4nB-4pk1A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f9d NANOBODY NB-ER19

(Lama glama) 		PF07686
(V-set) 		4 VAL C  57
GLY C  56
ARG C  72
VAL C  34
 None
 1.25A 5d4nA-5f9dC:
undetectable
5d4nB-5f9dC:
undetectable		 5d4nA-5f9dC:
19.57
5d4nB-5f9dC:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ic1 TALIN-1

(Mus musculus) 		no annotation 4 VAL A1449
GLY A1448
ARG A1593
VAL A1381
 None
 1.38A 5d4nA-5ic1A:
undetectable
5d4nB-5ic1A:
undetectable		 5d4nA-5ic1A:
11.90
5d4nB-5ic1A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j57 VHH SINGLE CHAIN
ANTIBODY V5E1

(Vicugna pacos) 		PF07686
(V-set) 		4 VAL B 115
GLY B 114
ARG B 116
VAL B   2
 None
 1.38A 5d4nA-5j57B:
undetectable
5d4nB-5j57B:
undetectable		 5d4nA-5j57B:
22.05
5d4nB-5j57B:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lo9 CYTOCHROME C

(Marichromatium
purpuratum) 		PF00034
(Cytochrom_C)
PF13442
(Cytochrome_CBB3) 		4 VAL A  80
GLY A   5
ARG A   4
VAL A  75
 HEC  A1001 (-4.4A)
None
None
None
 1.33A 5d4nA-5lo9A:
undetectable
5d4nB-5lo9A:
undetectable		 5d4nA-5lo9A:
12.89
5d4nB-5lo9A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6m APOLIPOPROTEIN
N-ACYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF00795
(CN_hydrolase) 		4 VAL A 227
GLY A 466
ARG A 465
VAL A 262
 None
 1.15A 5d4nA-5n6mA:
undetectable
5d4nB-5n6mA:
undetectable		 5d4nA-5n6mA:
11.91
5d4nB-5n6mA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x59 S PROTEIN

(Middle East
respiratory
syndrome-related
coronavirus) 		PF01601
(Corona_S2)
PF09408
(Spike_rec_bind) 		4 VAL A 958
GLY A 959
ARG A 979
VAL A1107
 None
 1.11A 5d4nA-5x59A:
undetectable
5d4nB-5x59A:
undetectable		 5d4nA-5x59A:
6.30
5d4nB-5x59A:
6.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bz0 DIHYDROLIPOYL
DEHYDROGENASE

(Acinetobacter
baumannii) 		no annotation 4 VAL A 155
GLY A 277
ARG A 278
VAL A 153
 None
None
FAD  A 501 ( 3.7A)
None
 1.45A 5d4nA-6bz0A:
undetectable
5d4nB-6bz0A:
undetectable		 5d4nA-6bz0A:
undetectable
5d4nB-6bz0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cet GATOR COMPLEX
PROTEIN DEPDC5

(Homo sapiens) 		no annotation 4 VAL D 987
GLY D 985
ARG D 988
VAL D 990
 None
 1.25A 5d4nA-6cetD:
undetectable
5d4nB-6cetD:
3.5		 5d4nA-6cetD:
undetectable
5d4nB-6cetD:
undetectable