SIMILAR PATTERNS OF AMINO ACIDS FOR 5CVT_B_ACTB200

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fu1 DNA REPAIR PROTEIN
XRCC4

(Homo sapiens) 		PF06632
(XRCC4) 		3 ASN A 118
ALA A 120
ARG A 124
 None
 0.35A 5cvtB-1fu1A:
undetectable		 5cvtB-1fu1A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fym HEAT SHOCK
TRANSCRIPTION
PROTEIN

(Kluyveromyces
lactis) 		PF00447
(HSF_DNA-bind) 		3 ASN A 244
ALA A 246
ARG A 250
 None
 0.64A 5cvtB-1fymA:
undetectable		 5cvtB-1fymA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gz0 HYPOTHETICAL
TRNA/RRNA
METHYLTRANSFERASE
YJFH

(Escherichia
coli) 		PF00588
(SpoU_methylase)
PF08032
(SpoU_sub_bind) 		3 ASN A 156
ALA A 158
ARG A 162
 None
 0.48A 5cvtB-1gz0A:
4.5		 5cvtB-1gz0A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j1i META CLEAVAGE
COMPOUND HYDROLASE

(Janthinobacterium) 		PF12697
(Abhydrolase_6) 		3 ASN A  54
ALA A  49
ARG A 185
 None
 0.48A 5cvtB-1j1iA:
3.6		 5cvtB-1j1iA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pg5 ASPARTATE
CARBAMOYLTRANSFERASE

(Sulfolobus
acidocaldarius) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		3 ASN A  83
ALA A  85
ARG A  89
 None
 0.77A 5cvtB-1pg5A:
7.6		 5cvtB-1pg5A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q2z ATP-DEPENDENT DNA
HELICASE II, 80 KDA
SUBUNIT

(Homo sapiens) 		PF08785
(Ku_PK_bind) 		3 ASN A   4
ALA A   6
ARG A  10
 None
 0.61A 5cvtB-1q2zA:
undetectable		 5cvtB-1q2zA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1su7 CARBON MONOXIDE
DEHYDROGENASE 2

(Carboxydothermus
hydrogenoformans) 		PF03063
(Prismane) 		3 ASN A 255
ALA A 323
ARG A 389
 None
 0.72A 5cvtB-1su7A:
5.9		 5cvtB-1su7A:
16.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1u11 PURE
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
MUTASE)

(Acetobacter
aceti) 		PF00731
(AIRC) 		3 ASN A 155
ALA A 157
ARG A 161
 None
 0.15A 5cvtB-1u11A:
31.7		 5cvtB-1u11A:
98.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2e 2-HYDROXY-6-KETONONA
-2,4-DIENEDIOIC ACID
HYDROLASE

(Escherichia
coli) 		PF12697
(Abhydrolase_6) 		3 ASN A  49
ALA A  44
ARG A 188
 CL  A1002 ( 3.8A)
CL  A1002 (-3.5A)
CL  A1002 (-3.5A)
 0.56A 5cvtB-1u2eA:
4.0		 5cvtB-1u2eA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a2a DEATH-ASSOCIATED
PROTEIN KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		3 ASN A 280
ALA A 283
ARG A 287
 None
 0.76A 5cvtB-2a2aA:
undetectable		 5cvtB-2a2aA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d3l GLUCAN
1,4-ALPHA-MALTOHEXAO
SIDASE

(Bacillus sp.
707) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		3 ASN A   6
ALA A 397
ARG A 415
 None
 0.78A 5cvtB-2d3lA:
undetectable		 5cvtB-2d3lA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g2k EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5

(Homo sapiens) 		PF01873
(eIF-5_eIF-2B) 		3 ASN A  83
ALA A  82
ARG A  20
 None
 0.73A 5cvtB-2g2kA:
undetectable		 5cvtB-2g2kA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h5x HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVA

(Mycobacterium
tuberculosis) 		PF01330
(RuvA_N)
PF07499
(RuvA_C)
PF14520
(HHH_5) 		3 ASN A 105
ALA A 107
ARG A 111
 None
 0.43A 5cvtB-2h5xA:
undetectable		 5cvtB-2h5xA:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuu DNA TRANSLOCASE FTSK

(Pseudomonas
aeruginosa) 		PF01580
(FtsK_SpoIIIE) 		3 ASN A 549
ALA A 551
ARG A 555
 None
 0.56A 5cvtB-2iuuA:
undetectable		 5cvtB-2iuuA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ivf ETHYLBENZENE
DEHYDROGENASE
GAMMA-SUBUNIT

(Aromatoleum
aromaticum) 		PF09459
(EB_dh) 		3 ASN C 194
ALA C 195
ARG C 200
 None
None
GOL  C1216 (-4.1A)
 0.78A 5cvtB-2ivfC:
undetectable		 5cvtB-2ivfC:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7a CYTOCHROME C QUINOL
DEHYDROGENASE NRFH

(Desulfovibrio
vulgaris) 		PF03264
(Cytochrom_NNT) 		3 ASN C  63
ALA C  62
ARG C  40
 None
 0.78A 5cvtB-2j7aC:
undetectable		 5cvtB-2j7aC:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okx RHAMNOSIDASE B

(Bacillus sp.
GL1) 		PF05592
(Bac_rhamnosid)
PF08531
(Bac_rhamnosid_N)
PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		3 ASN A 646
ALA A 648
ARG A 652
 None
 0.25A 5cvtB-2okxA:
undetectable		 5cvtB-2okxA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oml RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE E

(Escherichia
coli) 		PF00849
(PseudoU_synth_2) 		3 ASN A  91
ALA A  93
ARG A  97
 None
 0.71A 5cvtB-2omlA:
undetectable		 5cvtB-2omlA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2or0 HYDROXYLASE

(Rhodococcus
jostii) 		PF08028
(Acyl-CoA_dh_2) 		3 ASN A 205
ALA A 207
ARG A 213
 ACT  A 601 (-3.6A)
ACT  A 601 ( 4.3A)
ACT  A 601 ( 3.3A)
 0.78A 5cvtB-2or0A:
undetectable		 5cvtB-2or0A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qul D-TAGATOSE
3-EPIMERASE

(Pseudomonas
cichorii) 		PF01261
(AP_endonuc_2) 		3 ASN A 190
ALA A 215
ARG A 224
 None
 0.68A 5cvtB-2qulA:
undetectable		 5cvtB-2qulA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qw6 AAA ATPASE, CENTRAL
REGION

(Enterococcus
faecium) 		PF12002
(MgsA_C)
PF16193
(AAA_assoc_2) 		3 ASN A 291
ALA A 293
ARG A 297
 None
 0.31A 5cvtB-2qw6A:
undetectable		 5cvtB-2qw6A:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9g AAA ATPASE, CENTRAL
REGION

(Enterococcus
faecium) 		PF12002
(MgsA_C) 		3 ASN A 291
ALA A 293
ARG A 297
 None
 0.26A 5cvtB-2r9gA:
undetectable		 5cvtB-2r9gA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ri6 2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE

(Paraburkholderia
xenovorans) 		PF12697
(Abhydrolase_6) 		3 ASN A  51
ALA A  46
ARG A 190
 None
MLI  A   2 ( 4.6A)
MLI  A   2 ( 4.8A)
 0.72A 5cvtB-2ri6A:
4.1		 5cvtB-2ri6A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ru9 PREDICTED
TRANSPORTER

(Escherichia
coli) 		no annotation 3 ASN A  21
ALA A  23
ARG A  27
 None
 0.56A 5cvtB-2ru9A:
undetectable		 5cvtB-2ru9A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vrp AGGRETIN BETA CHAIN

(Calloselasma
rhodostoma) 		PF00059
(Lectin_C) 		3 ASN B  22
ALA B  24
ARG B  28
 None
 0.45A 5cvtB-2vrpB:
undetectable		 5cvtB-2vrpB:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wp8 EXOSOME COMPLEX
EXONUCLEASE DIS3

(Saccharomyces
cerevisiae) 		PF00773
(RNB)
PF13638
(PIN_4)
PF17215
(Rrp44_S1)
PF17216
(Rrp44_CSD1) 		3 ASN J 150
ALA J 173
ARG J 169
 None
 0.79A 5cvtB-2wp8J:
undetectable		 5cvtB-2wp8J:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wyr COBALT-ACTIVATED
PEPTIDASE TET1

(Pyrococcus
horikoshii) 		PF05343
(Peptidase_M42) 		3 ASN A 216
ALA A 215
ARG A 292
 None
 0.75A 5cvtB-2wyrA:
5.5		 5cvtB-2wyrA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xvr MAJOR CAPSID PROTEIN
10A

(Escherichia
virus T7) 		no annotation 3 ASN A 315
ALA A 314
ARG A 312
 None
 0.79A 5cvtB-2xvrA:
undetectable		 5cvtB-2xvrA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yo3 GENERAL CONTROL
PROTEIN GCN4,
PUTATIVE INNER
MEMBRANE PROTEIN,
GENERAL CONTROL
PROTEIN GCN4

(Saccharomyces
cerevisiae;
Salmonella
enterica) 		PF05662
(YadA_stalk) 		3 ASN A1354
ALA A1356
ARG A1360
 None
 0.53A 5cvtB-2yo3A:
undetectable		 5cvtB-2yo3A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zb4 PROSTAGLANDIN
REDUCTASE 2

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		3 ASN A 212
ALA A 214
ARG A 218
 None
 0.51A 5cvtB-2zb4A:
2.0		 5cvtB-2zb4A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bx4 AGGRETIN BETA CHAIN

(Calloselasma
rhodostoma) 		PF00059
(Lectin_C) 		3 ASN B  22
ALA B  24
ARG B  28
 None
 0.76A 5cvtB-3bx4B:
undetectable		 5cvtB-3bx4B:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmg PUTATIVE
BETA-GALACTOSIDASE

(Bacteroides
fragilis) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982) 		3 ASN A 477
ALA A 460
ARG A 356
 PO4  A 810 (-4.4A)
None
None
 0.65A 5cvtB-3cmgA:
2.7		 5cvtB-3cmgA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cp2 TRNA URIDINE
5-CARBOXYMETHYLAMINO
METHYL MODIFICATION
ENZYME GIDA

(Escherichia
coli) 		PF01134
(GIDA)
PF13932
(GIDA_assoc) 		3 ASN A  48
ALA A  50
ARG A  96
 None
 0.68A 5cvtB-3cp2A:
5.6		 5cvtB-3cp2A:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwo PROBABLE OUTER
MEMBRANE PROTEIN

(Pseudomonas
aeruginosa) 		PF03349
(Toluene_X) 		3 ASN X   9
ALA X  11
ARG X  15
 None
 0.66A 5cvtB-3dwoX:
undetectable		 5cvtB-3dwoX:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e1t HALOGENASE

(Chondromyces
crocatus) 		PF04820
(Trp_halogenase) 		3 ASN A 369
ALA A 214
ARG A  82
 None
 0.74A 5cvtB-3e1tA:
3.8		 5cvtB-3e1tA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egc PUTATIVE RIBOSE
OPERON REPRESSOR

(Burkholderia
thailandensis) 		PF00532
(Peripla_BP_1) 		3 ASN A 104
ALA A 106
ARG A 111
 None
 0.77A 5cvtB-3egcA:
10.5		 5cvtB-3egcA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ezy DEHYDROGENASE

(Thermotoga
maritima) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 ASN A  98
ALA A 100
ARG A 104
 None
 0.79A 5cvtB-3ezyA:
6.0		 5cvtB-3ezyA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fj4 MUCONATE
CYCLOISOMERASE

(Pseudomonas
protegens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASN A 233
ALA A 235
ARG A 239
 None
 0.60A 5cvtB-3fj4A:
3.9		 5cvtB-3fj4A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fok UNCHARACTERIZED
PROTEIN CGL0159

(Corynebacterium
glutamicum) 		no annotation 3 ASN A  62
ALA A  58
ARG A 119
 None
 0.62A 5cvtB-3fokA:
undetectable		 5cvtB-3fokA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g85 TRANSCRIPTIONAL
REGULATOR (LACI
FAMILY)

(Clostridium
acetobutylicum) 		PF13377
(Peripla_BP_3) 		3 ASN A 193
ALA A 195
ARG A 199
 GOL  A 401 ( 3.8A)
GOL  A 401 ( 4.4A)
GOL  A 401 (-2.9A)
 0.67A 5cvtB-3g85A:
7.1		 5cvtB-3g85A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lcv SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM

(Micromonospora
zionensis) 		PF07091
(FmrO) 		3 ASN B  71
ALA B  73
ARG B  77
 None
 0.27A 5cvtB-3lcvB:
undetectable		 5cvtB-3lcvB:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lsp DEST

(Pseudomonas
aeruginosa) 		PF00440
(TetR_N) 		3 ASN A  81
ALA A  91
ARG A  94
 None
 0.66A 5cvtB-3lspA:
undetectable		 5cvtB-3lspA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n4p TERMINASE SUBUNIT
UL89 PROTEIN

(Human
betaherpesvirus
5) 		PF02499
(DNA_pack_C) 		3 ASN A 538
ALA A 540
ARG A 544
 None
 0.39A 5cvtB-3n4pA:
undetectable		 5cvtB-3n4pA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nrg TETR FAMILY
TRANSCRIPTIONAL
REGULATOR

(Chloroflexus
aurantiacus) 		PF00440
(TetR_N) 		3 ASN A 181
ALA A 183
ARG A 187
 None
 0.77A 5cvtB-3nrgA:
undetectable		 5cvtB-3nrgA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oyt 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE I

(Yersinia pestis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		3 ASN A 373
ALA A 324
ARG A 381
 None
 0.74A 5cvtB-3oytA:
undetectable		 5cvtB-3oytA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q6m HEAT SHOCK PROTEIN
HSP 90-ALPHA

(Homo sapiens) 		PF00183
(HSP90) 		3 ASN A 504
ALA A 503
ARG A 512
 None
 0.53A 5cvtB-3q6mA:
3.0		 5cvtB-3q6mA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rcp PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY A MEMBER 3

(Homo sapiens) 		PF00169
(PH) 		3 ASN A  77
ALA A  79
ARG A  83
 None
 0.53A 5cvtB-3rcpA:
undetectable		 5cvtB-3rcpA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rkv PUTATIVE
PEPTIDYLPROLYL
ISOMERASE

(Caenorhabditis
elegans) 		PF13181
(TPR_8) 		3 ASN A 248
ALA A 247
ARG A 282
 None
 0.70A 5cvtB-3rkvA:
undetectable		 5cvtB-3rkvA:
27.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sr2 DNA REPAIR PROTEIN
XRCC4

(Homo sapiens) 		PF06632
(XRCC4) 		3 ASN A 118
ALA A 120
ARG A 124
 None
 0.69A 5cvtB-3sr2A:
undetectable		 5cvtB-3sr2A:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uet ALPHA-1,3/4-FUCOSIDA
SE

(Bifidobacterium
longum) 		PF01120
(Alpha_L_fucos) 		3 ASN A  16
ALA A  15
ARG A 417
 None
 0.78A 5cvtB-3uetA:
2.6		 5cvtB-3uetA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE

(Oryza sativa) 		PF00875
(DNA_photolyase) 		3 ASN A 462
ALA A 464
ARG A 468
 None
 0.62A 5cvtB-3umvA:
2.4		 5cvtB-3umvA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE

(Sinorhizobium
meliloti) 		PF13561
(adh_short_C2) 		3 ASN A 270
ALA A 269
ARG A 231
 None
 0.73A 5cvtB-3v2gA:
4.3		 5cvtB-3v2gA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w03 DNA REPAIR PROTEIN
XRCC4

(Homo sapiens) 		PF06632
(XRCC4) 		3 ASN C 118
ALA C 120
ARG C 124
 None
 0.35A 5cvtB-3w03C:
undetectable		 5cvtB-3w03C:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfa ALPHA-GLUCOSIDASE

(Bacteroides
thetaiotaomicron) 		PF10566
(Glyco_hydro_97)
PF14508
(GH97_N)
PF14509
(GH97_C) 		3 ASN A 369
ALA A 371
ARG A 375
 None
 0.45A 5cvtB-3wfaA:
2.1		 5cvtB-3wfaA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4amc GLUCANSUCRASE

(Lactobacillus
reuteri) 		PF01473
(CW_binding_1)
PF02324
(Glyco_hydro_70) 		3 ASN A1225
ALA A1311
ARG A1309
 None
 0.67A 5cvtB-4amcA:
undetectable		 5cvtB-4amcA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ep6 CYTOCHROME P450-LIKE
PROTEIN XPLA

(Rhodococcus
rhodochrous) 		PF00067
(p450) 		3 ASN A 538
ALA A 541
ARG A 543
 None
 0.79A 5cvtB-4ep6A:
undetectable		 5cvtB-4ep6A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fe9 OUTER MEMBRANE
PROTEIN SUSF

(Bacteroides
thetaiotaomicron) 		PF16411
(SusF_SusE)
PF17142
(DUF5115) 		3 ASN A 264
ALA A 122
ARG A 126
 None
 0.62A 5cvtB-4fe9A:
undetectable		 5cvtB-4fe9A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igl YENB

(Yersinia
entomophaga) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN) 		3 ASN A 712
ALA A1305
ARG A1309
 None
 0.75A 5cvtB-4iglA:
undetectable		 5cvtB-4iglA:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k35 GLYCOSIDE HYDROLASE
FAMILY 81
ENDO-BETA-1,3-GLUCAN
ASE

(Rhizomucor
miehei) 		PF03639
(Glyco_hydro_81) 		3 ASN A 689
ALA A 691
ARG A 724
 None
 0.57A 5cvtB-4k35A:
undetectable		 5cvtB-4k35A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lxi MCP HYDROLASE

(Sphingomonas
wittichii) 		PF12697
(Abhydrolase_6) 		3 ASN A  43
ALA A  38
ARG A 180
 22J  A 301 (-2.9A)
22J  A 301 (-3.4A)
22J  A 301 (-2.9A)
 0.74A 5cvtB-4lxiA:
4.1		 5cvtB-4lxiA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4na3 POLYKETIDE SYNTHASE
PKSJ

(Bacillus
subtilis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		3 ASN A 192
ALA A 189
ARG A 185
 None
 0.73A 5cvtB-4na3A:
undetectable		 5cvtB-4na3A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4npa PUTATIVE
UNCHARACTERIZED
PROTEIN

(Vibrio cholerae) 		PF03641
(Lysine_decarbox)
PF11892
(DUF3412)
PF14793
(DUF4478) 		3 ASN A 323
ALA A 325
ARG A 329
 None
 0.49A 5cvtB-4npaA:
2.7		 5cvtB-4npaA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pwn SERINE/THREONINE-PRO
TEIN KINASE WNK1

(Homo sapiens) 		PF00069
(Pkinase) 		3 ASN A 427
ALA A 429
ARG A 433
 None
 0.68A 5cvtB-4pwnA:
undetectable		 5cvtB-4pwnA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pzv 2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE/DI
HYDROPTEROATE
SYNTHASE

(Francisella
tularensis) 		PF00809
(Pterin_bind)
PF01288
(HPPK) 		3 ASN A 393
ALA A 395
ARG A 399
 None
 0.77A 5cvtB-4pzvA:
undetectable		 5cvtB-4pzvA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q68 UNCHARACTERIZED
PROTEIN

(Bacteroides
uniformis) 		PF07313
(DUF1460) 		3 ASN A 118
ALA A 114
ARG A 256
 None
 0.47A 5cvtB-4q68A:
undetectable		 5cvtB-4q68A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qeo HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH4

(Arabidopsis
thaliana) 		PF00856
(SET)
PF02182
(SAD_SRA)
PF05033
(Pre-SET) 		3 ASN A 582
ALA A 468
ARG A 414
 None
 0.48A 5cvtB-4qeoA:
undetectable		 5cvtB-4qeoA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rpa PROBABLE
MANGANESE-DEPENDENT
INORGANIC
PYROPHOSPHATASE

(Staphylococcus
aureus) 		PF01368
(DHH)
PF02833
(DHHA2) 		3 ASN A  11
ALA A 204
ARG A 215
 None
 0.77A 5cvtB-4rpaA:
undetectable		 5cvtB-4rpaA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rrp ANTIGEN ASF1P

(Saccharomyces
cerevisiae) 		PF04729
(ASF1_hist_chap) 		3 ASN M  13
ALA M  16
ARG M 137
 None
 0.78A 5cvtB-4rrpM:
undetectable		 5cvtB-4rrpM:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u1a ENOYL-COA DELTA
ISOMERASE 2

(Homo sapiens) 		PF00378
(ECH_1) 		3 ASN A 334
ALA A 330
ARG A 190
 None
 0.70A 5cvtB-4u1aA:
3.3		 5cvtB-4u1aA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wcx BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED

(Thermoanaerobacter
italicus) 		PF04055
(Radical_SAM)
PF06968
(BATS) 		3 ASN A 409
ALA A 382
ARG A 388
 SF4  A 502 (-4.6A)
SF4  A 502 ( 4.1A)
SF4  A 502 ( 4.7A)
 0.57A 5cvtB-4wcxA:
2.3		 5cvtB-4wcxA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zbt ACETOACETATE
DECARBOXYLASE

(Streptomyces
bingchenggensis) 		PF06314
(ADC) 		3 ASN A 108
ALA A 110
ARG A 114
 None
None
PYR  A 301 (-3.7A)
 0.46A 5cvtB-4zbtA:
undetectable		 5cvtB-4zbtA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c70 GLUCURONIDASE

(Aspergillus
oryzae) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		3 ASN A 467
ALA A 445
ARG A 329
 None
 0.77A 5cvtB-5c70A:
undetectable		 5cvtB-5c70A:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cqf L-LYSINE
6-MONOOXYGENASE

(Pseudomonas
syringae group
genomosp. 3) 		PF13434
(K_oxygenase) 		3 ASN A 263
ALA A 265
ARG A 269
 None
 0.49A 5cvtB-5cqfA:
3.4		 5cvtB-5cqfA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cxw PENICILLIN-BINDING
PROTEIN 1A

(Mycobacterium
tuberculosis) 		PF00905
(Transpeptidase) 		3 ASN A 319
ALA A 321
ARG A 323
 None
 0.79A 5cvtB-5cxwA:
undetectable		 5cvtB-5cxwA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eaw DNA REPLICATION
ATP-DEPENDENT
HELICASE/NUCLEASE
DNA2

(Mus musculus) 		PF08696
(Dna2)
PF13086
(AAA_11)
PF13087
(AAA_12) 		3 ASN A 856
ALA A 855
ARG A 832
 None
 0.61A 5cvtB-5eawA:
undetectable		 5cvtB-5eawA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ec0 ALP7A

(Bacillus
subtilis) 		no annotation 3 ASN A 313
ALA A 309
ARG A 346
 None
 0.74A 5cvtB-5ec0A:
undetectable		 5cvtB-5ec0A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fmu TRAF3-INTERACTING
PROTEIN 1

(Mus musculus) 		PF10243
(MIP-T3) 		3 ASN A   2
ALA A   4
ARG A   8
 None
 0.60A 5cvtB-5fmuA:
undetectable		 5cvtB-5fmuA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g2v N-ACETYLGLUCOSAMINE-
6-SULFATASE

(Bacteroides
thetaiotaomicron) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		3 ASN A 325
ALA A 321
ARG A 207
 None
 0.43A 5cvtB-5g2vA:
undetectable		 5cvtB-5g2vA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h8w ATP-DEPENDENT DNA
HELICASE TA0057

(Thermoplasma
acidophilum) 		PF06733
(DEAD_2)
PF06777
(HBB)
PF13307
(Helicase_C_2) 		3 ASN A 114
ALA A 110
ARG A  88
 None
 0.57A 5cvtB-5h8wA:
2.1		 5cvtB-5h8wA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdg HEAT SHOCK FACTOR
PROTEIN 1

(Homo sapiens) 		PF00447
(HSF_DNA-bind) 		3 ASN A  65
ALA A  67
ARG A  71
 None
 0.39A 5cvtB-5hdgA:
undetectable		 5cvtB-5hdgA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i33 ADENYLOSUCCINATE
SYNTHETASE

(Cryptococcus
neoformans) 		PF00709
(Adenylsucc_synt) 		3 ASN A  43
ALA A 228
ARG A  37
 None
 0.72A 5cvtB-5i33A:
undetectable		 5cvtB-5i33A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k6o B-GLUCOSIDASE

(metagenome) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 ASN A 725
ALA A 727
ARG A 731
 None
 0.47A 5cvtB-5k6oA:
3.9		 5cvtB-5k6oA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kqi CATALASE-PEROXIDASE

(Burkholderia
pseudomallei) 		PF00141
(peroxidase) 		3 ASN A 516
ALA A 515
ARG A 602
 None
 0.75A 5cvtB-5kqiA:
undetectable		 5cvtB-5kqiA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l7z MATERNAL PROTEIN
EXUPERANTIA

(Drosophila
melanogaster) 		no annotation 3 ASN A  74
ALA A  76
ARG A  80
 None
 0.54A 5cvtB-5l7zA:
undetectable		 5cvtB-5l7zA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldr BETA-D-GALACTOSIDASE

(Paracoccus sp.
32d) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		3 ASN B 123
ALA B 125
ARG B 338
 None
 0.70A 5cvtB-5ldrB:
2.5		 5cvtB-5ldrB:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mun LYS-GINGIPAIN W83

(Porphyromonas
gingivalis) 		PF08126
(Propeptide_C25) 		3 ASN A 141
ALA A 143
ARG A 147
 None
 0.11A 5cvtB-5munA:
undetectable		 5cvtB-5munA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o1m RUBBER OXYGENASE

(Streptomyces
sp. K30) 		PF09995
(DUF2236) 		3 ASN A 250
ALA A 252
ARG A 118
 None
 0.75A 5cvtB-5o1mA:
undetectable		 5cvtB-5o1mA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ojs TRANSCRIPTION-ASSOCI
ATED PROTEIN 1

(Saccharomyces
cerevisiae) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT) 		3 ASN T 695
ALA T 696
ARG T1585
 None
 0.52A 5cvtB-5ojsT:
undetectable		 5cvtB-5ojsT:
3.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tsh TYPE IV PILUS
BIOGENESIS ATPASE
PILB

(Geobacter
metallireducens) 		PF00437
(T2SSE) 		3 ASN A 526
ALA A 528
ARG A 532
 None
 0.70A 5cvtB-5tshA:
undetectable		 5cvtB-5tshA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj6 GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN
PROTEIN

(Bacteroides
uniformis) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF11721
(Malectin)
PF16355
(DUF4982) 		3 ASN A 400
ALA A 127
ARG A 157
 None
 0.66A 5cvtB-5uj6A:
undetectable		 5cvtB-5uj6A:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj6 GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN
PROTEIN

(Bacteroides
uniformis) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF11721
(Malectin)
PF16355
(DUF4982) 		3 ASN A 493
ALA A 471
ARG A 360
 GOL  A 901 (-4.4A)
None
GOL  A 901 ( 4.9A)
 0.79A 5cvtB-5uj6A:
undetectable		 5cvtB-5uj6A:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vjc PROTEIN MINI
SPINDLES

(Drosophila
melanogaster) 		no annotation 3 ASN A1151
ALA A1189
ARG A1157
 None
 0.49A 5cvtB-5vjcA:
undetectable		 5cvtB-5vjcA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wlz DNA REPAIR PROTEIN
XRCC4,MYOSIN-7

(Homo sapiens) 		no annotation 3 ASN C 118
ALA C 120
ARG C 124
 None
 0.36A 5cvtB-5wlzC:
undetectable		 5cvtB-5wlzC:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wq8 TYPE II SECRETION
SYSTEM PROTEIN D

(Vibrio cholerae) 		PF00263
(Secretin)
PF03958
(Secretin_N) 		3 ASN A 506
ALA A 519
ARG A 521
 None
 0.77A 5cvtB-5wq8A:
undetectable		 5cvtB-5wq8A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yti FLAGELLAR HOOK
ASSOCIATED PROTEIN
TYPE 3 FLGL

(Legionella
pneumophila) 		no annotation 3 ASN A 324
ALA A  97
ARG A 107
 None
 0.57A 5cvtB-5ytiA:
undetectable		 5cvtB-5ytiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3r PIEZO-TYPE
MECHANOSENSITIVE ION
CHANNEL COMPONENT 1

(Mus musculus) 		no annotation 3 ASN A2161
ALA A2160
ARG A2126
 None
 0.65A 5cvtB-6b3rA:
undetectable		 5cvtB-6b3rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btm ALTERNATIVE COMPLEX
III SUBUNIT B
ALTERNATIVE COMPLEX
III SUBUNIT E

(Flavobacterium
johnsoniae;
Flavobacterium
johnsoniae) 		no annotation
no annotation 		3 ASN B 123
ALA B  96
ARG E  65
 None
 0.74A 5cvtB-6btmB:
3.4		 5cvtB-6btmB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6elq CARBON MONOXIDE
DEHYDROGENASE

(Carboxydothermus
hydrogenoformans) 		no annotation 3 ASN X 255
ALA X 323
ARG X 389
 None
 0.73A 5cvtB-6elqX:
6.9		 5cvtB-6elqX:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fa5 PUTATIVE MRNA
SPLICING FACTOR

(Chaetomium
thermophilum) 		no annotation 3 ASN A 620
ALA A 619
ARG A 636
 None
 0.73A 5cvtB-6fa5A:
undetectable		 5cvtB-6fa5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fdt -

(-) 		no annotation 3 ASN A 321
ALA A 320
ARG A 355
 None
 0.70A 5cvtB-6fdtA:
undetectable		 5cvtB-6fdtA:
undetectable