SIMILAR PATTERNS OF AMINO ACIDS FOR 5CU6_A_ACTA403

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b7f PROTEIN (SXL-LETHAL
PROTEIN)

(Drosophila
melanogaster) 		PF00076
(RRM_1) 		4 ILE A 242
VAL A 215
PRO A 219
ALA A 255
 None
 0.68A 5cu6A-1b7fA:
undetectable		 5cu6A-1b7fA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bpl ALPHA-1,4-GLUCAN-4-G
LUCANOHYDROLASE

(Bacillus
licheniformis) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		4 VAL B 283
ASP B 285
PRO B 287
ALA B 320
 None
 0.92A 5cu6A-1bplB:
undetectable		 5cu6A-1bplB:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dbi AK.1 SERINE PROTEASE

(Bacillus sp.
Ak1) 		PF00082
(Peptidase_S8) 		4 TYR A 122
ILE A 131
VAL A 102
ALA A  36
 None
 0.83A 5cu6A-1dbiA:
undetectable		 5cu6A-1dbiA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6y METHYL-COENZYME M
REDUCTASE I BETA
SUBUNIT

(Methanosarcina
barkeri) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		4 TYR B2292
ILE B2278
VAL B2270
ALA B2273
 None
 0.83A 5cu6A-1e6yB:
undetectable		 5cu6A-1e6yB:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1evq SERINE HYDROLASE

(Alicyclobacillus
acidocaldarius) 		PF07859
(Abhydrolase_3) 		4 TYR A  74
ILE A 149
VAL A 107
ALA A  76
 None
 0.93A 5cu6A-1evqA:
undetectable		 5cu6A-1evqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE

(Hydrogenophaga
pseudoflava) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 TYR B 530
ILE B 505
VAL B 547
ALA B 515
 None
 0.83A 5cu6A-1ffvB:
undetectable		 5cu6A-1ffvB:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gn4 SUPEROXIDE DISMUTASE

(Mycobacterium
tuberculosis) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		4 TYR A   4
VAL A  44
ASP A  42
ALA A  43
 None
 0.90A 5cu6A-1gn4A:
undetectable		 5cu6A-1gn4A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyc LACCASE 2

(Trametes
versicolor) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.79A 5cu6A-1gycA:
undetectable		 5cu6A-1gycA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kya LACCASE

(Trametes
versicolor) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.78A 5cu6A-1kyaA:
undetectable		 5cu6A-1kyaA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lfw PEPV

(Lactobacillus
delbrueckii) 		PF01546
(Peptidase_M20) 		4 VAL A 235
ASP A 231
PRO A 230
ALA A 234
 None
 0.87A 5cu6A-1lfwA:
undetectable		 5cu6A-1lfwA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pby QUINOHEMOPROTEIN
AMINE DEHYDROGENASE
40 KDA SUBUNIT

(Paracoccus
denitrificans) 		no annotation 4 ILE B  61
VAL B  41
PRO B  39
ALA B  48
 None
 0.89A 5cu6A-1pbyB:
undetectable		 5cu6A-1pbyB:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pix GLUTACONYL-COA
DECARBOXYLASE A
SUBUNIT

(Acidaminococcus
fermentans) 		PF01039
(Carboxyl_trans) 		4 TYR A 323
ILE A 411
VAL A 347
ALA A 362
 None
 0.75A 5cu6A-1pixA:
undetectable		 5cu6A-1pixA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q47 SEMAPHORIN 3A

(Mus musculus) 		PF01403
(Sema) 		4 TYR A  36
ILE A 503
VAL A  45
ALA A 510
 None
 0.93A 5cu6A-1q47A:
undetectable		 5cu6A-1q47A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v10 LACCASE

(Rigidoporus
microporus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.84A 5cu6A-1v10A:
undetectable		 5cu6A-1v10A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v43 SUGAR-BINDING
TRANSPORT
ATP-BINDING PROTEIN

(Pyrococcus
horikoshii) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		4 TYR A 102
ILE A 132
VAL A 123
ALA A 127
 None
 0.80A 5cu6A-1v43A:
undetectable		 5cu6A-1v43A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrg PROPIONYL-COA
CARBOXYLASE, BETA
SUBUNIT

(Thermotoga
maritima) 		PF01039
(Carboxyl_trans) 		4 TYR A 470
ILE A 398
VAL A 481
ALA A 422
 None
 0.89A 5cu6A-1vrgA:
undetectable		 5cu6A-1vrgA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wd3 ALPHA-L-ARABINOFURAN
OSIDASE B

(Aspergillus
kawachii) 		PF05270
(AbfB)
PF09206
(ArabFuran-catal) 		4 TYR A 307
ILE A  71
VAL A 128
ALA A 135
 None
 0.82A 5cu6A-1wd3A:
undetectable		 5cu6A-1wd3A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x0u HYPOTHETICAL
METHYLMALONYL-COA
DECARBOXYLASE ALPHA
SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01039
(Carboxyl_trans) 		4 TYR A 478
ILE A 406
VAL A 489
ALA A 430
 None
 0.83A 5cu6A-1x0uA:
undetectable		 5cu6A-1x0uA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xny PROPIONYL-COA
CARBOXYLASE COMPLEX
B SUBUNIT

(Streptomyces
coelicolor) 		PF01039
(Carboxyl_trans) 		4 TYR A 485
ILE A 412
VAL A 496
ALA A 436
 None
 0.82A 5cu6A-1xnyA:
undetectable		 5cu6A-1xnyA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xp8 RECA PROTEIN

(Deinococcus
radiodurans) 		PF00154
(RecA) 		4 TYR A 304
ILE A 296
VAL A 288
ALA A 291
 None
 0.90A 5cu6A-1xp8A:
undetectable		 5cu6A-1xp8A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yln HYPOTHETICAL PROTEIN
VCA0042

(Vibrio cholerae) 		PF07238
(PilZ)
PF12945
(YcgR_2) 		4 ILE A 114
VAL A  71
PRO A  74
ALA A 122
 None
 0.91A 5cu6A-1ylnA:
undetectable		 5cu6A-1ylnA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yvc MRR5

(Methanococcus
maripaludis) 		PF01938
(TRAM) 		4 ILE A  23
VAL A  41
PRO A  44
ALA A  34
 None
 0.92A 5cu6A-1yvcA:
undetectable		 5cu6A-1yvcA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a7s PROBABLE
PROPIONYL-COA
CARBOXYLASE BETA
CHAIN 5

(Mycobacterium
tuberculosis) 		PF01039
(Carboxyl_trans) 		4 TYR A 503
ILE A 427
VAL A 514
ALA A 451
 None
 0.82A 5cu6A-2a7sA:
undetectable		 5cu6A-2a7sA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cwf DELTA1-PIPERIDEINE-2
-CARBOXYLATE
REDUCTASE

(Pseudomonas
syringae group
genomosp. 3) 		PF02615
(Ldh_2) 		4 VAL A 280
ASP A 282
PRO A 283
ALA A 111
 None
 0.75A 5cu6A-2cwfA:
undetectable		 5cu6A-2cwfA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1f THREONINE SYNTHASE

(Mycobacterium
tuberculosis) 		PF00291
(PALP) 		4 TYR A 103
ILE A 109
VAL A  32
ALA A 107
 None
 0.91A 5cu6A-2d1fA:
undetectable		 5cu6A-2d1fA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d3l GLUCAN
1,4-ALPHA-MALTOHEXAO
SIDASE

(Bacillus sp.
707) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		4 VAL A 288
ASP A 290
PRO A 292
ALA A 325
 None
 0.92A 5cu6A-2d3lA:
undetectable		 5cu6A-2d3lA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2die AMYLASE

(Bacillus sp.
(in: Bacteria)) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		4 VAL A 288
ASP A 290
PRO A 292
ALA A 325
 None
 0.84A 5cu6A-2dieA:
undetectable		 5cu6A-2dieA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2diu KIAA0430 PROTEIN

(Homo sapiens) 		PF11608
(Limkain-b1) 		4 ILE A  44
VAL A  14
PRO A  18
ALA A  49
 None
 0.91A 5cu6A-2diuA:
undetectable		 5cu6A-2diuA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2evr COG0791: CELL
WALL-ASSOCIATED
HYDROLASES
(INVASION-ASSOCIATED
PROTEINS)

(Nostoc
punctiforme) 		PF00877
(NLPC_P60) 		4 ILE A 155
VAL A 166
ASP A 164
ALA A 222
 None
 0.72A 5cu6A-2evrA:
undetectable		 5cu6A-2evrA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g4b SPLICING FACTOR U2AF
65 KDA SUBUNIT

(Homo sapiens) 		PF00076
(RRM_1) 		4 ILE A 191
VAL A 153
PRO A 157
ALA A 198
 None
 0.58A 5cu6A-2g4bA:
undetectable		 5cu6A-2g4bA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hbw NLP/P60 PROTEIN

(Trichormus
variabilis) 		PF00877
(NLPC_P60) 		4 ILE A 155
VAL A 166
ASP A 164
ALA A 222
 None
 0.81A 5cu6A-2hbwA:
undetectable		 5cu6A-2hbwA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hzh LACCASE

(Trametes
ochracea) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.78A 5cu6A-2hzhA:
undetectable		 5cu6A-2hzhA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2it1 362AA LONG
HYPOTHETICAL
MALTOSE/MALTODEXTRIN
TRANSPORT
ATP-BINDING PROTEIN

(Pyrococcus
horikoshii) 		PF00005
(ABC_tran) 		4 TYR A  93
ILE A 123
VAL A 114
ALA A 118
 None
 0.90A 5cu6A-2it1A:
undetectable		 5cu6A-2it1A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jan TYROSYL-TRNA
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00579
(tRNA-synt_1b) 		4 ILE A 192
VAL A  69
PRO A  67
ALA A  37
 None
 0.80A 5cu6A-2janA:
undetectable		 5cu6A-2janA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN

(Archaeoglobus
fulgidus) 		PF00005
(ABC_tran) 		4 TYR A  88
ILE A 116
VAL A 107
ALA A 111
 None
 0.82A 5cu6A-2onkA:
undetectable		 5cu6A-2onkA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2phk PHOSPHORYLASE KINASE

(Oryctolagus
cuniculus) 		PF00069
(Pkinase) 		4 TYR A 206
VAL A 210
PRO A 272
ALA A 191
 None
 0.90A 5cu6A-2phkA:
26.1		 5cu6A-2phkA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qt6 LACCASE

(Lentinus
tigrinus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.80A 5cu6A-2qt6A:
undetectable		 5cu6A-2qt6A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v5p CATION-INDEPENDENT
MANNOSE-6-PHOSPHATE
RECEPTOR

(Homo sapiens) 		PF00040
(fn2)
PF00878
(CIMR) 		4 TYR A1834
ILE A1953
VAL A1968
PRO A1966
 None
 0.91A 5cu6A-2v5pA:
undetectable		 5cu6A-2v5pA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w4o CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE IV

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR A 218
VAL A 222
PRO A 285
ALA A 209
 None
 0.83A 5cu6A-2w4oA:
21.4		 5cu6A-2w4oA:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2woz KELCH REPEAT AND BTB
DOMAIN-CONTAINING
PROTEIN 10

(Rattus
norvegicus) 		PF01344
(Kelch_1) 		4 ILE A 535
VAL A 512
PRO A 529
ALA A 500
 None
 0.82A 5cu6A-2wozA:
undetectable		 5cu6A-2wozA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x46 ALLERGEN ARG R 1

(Argas reflexus) 		PF02098
(His_binding) 		4 TYR A  69
ILE A  29
VAL A  94
ALA A  85
 None
 0.85A 5cu6A-2x46A:
undetectable		 5cu6A-2x46A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyb LACCASE

(Trametes
cinnabarina) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.76A 5cu6A-2xybA:
undetectable		 5cu6A-2xybA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1n NDP-SUGAR EPIMERASE

(Thermoplasma
volcanium) 		PF01370
(Epimerase) 		4 ILE A 290
ASP A 212
PRO A 211
ALA A 238
 None
 0.92A 5cu6A-3a1nA:
undetectable		 5cu6A-3a1nA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a2k TRNA(ILE)-LYSIDINE
SYNTHASE

(Geobacillus
kaustophilus) 		PF01171
(ATP_bind_3)
PF09179
(TilS)
PF11734
(TilS_C) 		4 VAL A 374
ASP A 376
PRO A 377
ALA A 446
 None
 0.66A 5cu6A-3a2kA:
undetectable		 5cu6A-3a2kA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a45 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE

(Acanthamoeba
polyphaga
mimivirus) 		PF01149
(Fapy_DNA_glyco)
PF06831
(H2TH) 		5 ILE A 285
VAL A 264
ASP A 258
PRO A 259
ALA A 282
 None
 1.28A 5cu6A-3a45A:
undetectable		 5cu6A-3a45A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5i FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA

(Salmonella
enterica) 		PF00771
(FHIPEP) 		4 ILE A 440
ASP A 456
PRO A 457
ALA A 463
 None
 0.91A 5cu6A-3a5iA:
undetectable		 5cu6A-3a5iA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9n ALKANE MONOOXYGENASE

(Geobacillus
thermodenitrificans) 		PF00296
(Bac_luciferase) 		4 TYR A 365
ILE A 372
VAL A 251
ALA A 370
 None
 0.78A 5cu6A-3b9nA:
undetectable		 5cu6A-3b9nA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c4q PREDICTED
GLYCOSYLTRANSFERASES

(Corynebacterium
glutamicum) 		PF00534
(Glycos_transf_1)
PF13439
(Glyco_transf_4) 		4 TYR A 303
ILE A 260
VAL A 309
ALA A 227
 None
 0.92A 5cu6A-3c4qA:
undetectable		 5cu6A-3c4qA:
21.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e3b CASEIN KINASE II
SUBUNIT ALPHA'

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR X  40
ILE X  70
VAL X 102
ALA X 111
 None
 0.50A 5cu6A-3e3bX:
46.9		 5cu6A-3e3bX:
84.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e3b CASEIN KINASE II
SUBUNIT ALPHA'

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR X  40
VAL X 102
PRO X 105
ALA X 111
 None
 0.86A 5cu6A-3e3bX:
46.9		 5cu6A-3e3bX:
84.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ef1 RNA POLYMERASE II
SUBUNIT A C-TERMINAL
DOMAIN PHOSPHATASE

(Schizosaccharomyces
pombe) 		PF03031
(NIF)
PF12738
(PTCB-BRCT) 		4 TYR A 580
ILE A 554
VAL A 545
ALA A 548
 None
 0.91A 5cu6A-3ef1A:
undetectable		 5cu6A-3ef1A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h4x PHOSPHATIDYLINOSITOL
-SPECIFIC
PHOSPHOLIPASE C1

(Streptomyces
antibioticus) 		PF16670
(PI-PLC-C1) 		4 ILE A 194
VAL A 258
ASP A 260
ALA A 234
 None
None
EOH  A 358 (-4.1A)
None
 0.50A 5cu6A-3h4xA:
undetectable		 5cu6A-3h4xA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hj7 TRNA(ILE)-LYSIDINE
SYNTHASE

(Geobacillus
kaustophilus) 		PF11734
(TilS_C) 		4 VAL A 374
ASP A 376
PRO A 377
ALA A 446
 None
None
None
CL  A   1 (-4.1A)
 0.71A 5cu6A-3hj7A:
undetectable		 5cu6A-3hj7A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3il4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3

(Enterococcus
faecalis) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 TYR A 278
ILE A  50
VAL A  18
ASP A 164
 None
 0.70A 5cu6A-3il4A:
undetectable		 5cu6A-3il4A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iln LAMINARINASE

(Rhodothermus
marinus) 		PF00722
(Glyco_hydro_16) 		4 ILE A 110
VAL A 143
PRO A 108
ALA A 133
 None
 0.92A 5cu6A-3ilnA:
undetectable		 5cu6A-3ilnA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jcm U4/U6 SMALL NUCLEAR
RIBONUCLEOPROTEIN
PRP4

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 TYR B 248
ILE B 224
VAL B 201
ALA B 191
 None
 0.73A 5cu6A-3jcmB:
undetectable		 5cu6A-3jcmB:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k0b PREDICTED
N6-ADENINE-SPECIFIC
DNA METHYLASE

(Listeria
monocytogenes) 		PF01170
(UPF0020)
PF02926
(THUMP) 		4 TYR A 336
ILE A 204
ASP A 196
PRO A 197
 None
 0.80A 5cu6A-3k0bA:
undetectable		 5cu6A-3k0bA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kw7 LACCASE B

(Trametes sp.
AH28-2) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.82A 5cu6A-3kw7A:
undetectable		 5cu6A-3kw7A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldu PUTATIVE METHYLASE

(Clostridioides
difficile) 		PF01170
(UPF0020)
PF02926
(THUMP) 		4 TYR A 338
ILE A 206
ASP A 198
PRO A 199
 None
 0.85A 5cu6A-3lduA:
undetectable		 5cu6A-3lduA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3npf PUTATIVE
DIPEPTIDYL-PEPTIDASE
VI

(Bacteroides
ovatus) 		PF00877
(NLPC_P60) 		4 ILE A 232
VAL A 247
ASP A 245
ALA A 303
 None
 0.88A 5cu6A-3npfA:
undetectable		 5cu6A-3npfA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oyz MALATE SYNTHASE

(Haloferax
volcanii) 		PF03328
(HpcH_HpaI) 		4 TYR A 406
ILE A 399
VAL A 425
ALA A 428
 None
 0.77A 5cu6A-3oyzA:
undetectable		 5cu6A-3oyzA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxl LACCASE

(Trametes
hirsuta) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.75A 5cu6A-3pxlA:
undetectable		 5cu6A-3pxlA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qh4 ESTERASE LIPW

(Mycobacterium
marinum) 		PF07859
(Abhydrolase_3) 		4 ILE A 184
VAL A  84
PRO A  82
ALA A 157
 None
 0.86A 5cu6A-3qh4A:
undetectable		 5cu6A-3qh4A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6w LACCASE

(Steccherinum
ochraceum) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 127
ASP A 129
PRO A 130
ALA A 104
 None
 0.77A 5cu6A-3t6wA:
undetectable		 5cu6A-3t6wA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqt D-ALANINE--D-ALANINE
LIGASE

(Coxiella
burnetii) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ILE A  53
VAL A  68
PRO A  64
ALA A  73
 None
 0.80A 5cu6A-3tqtA:
undetectable		 5cu6A-3tqtA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uf6 LMO1369 PROTEIN

(Listeria
monocytogenes) 		PF01515
(PTA_PTB) 		4 TYR A 241
ILE A 122
VAL A 245
ALA A 250
 COD  A 289 (-4.1A)
None
None
None
 0.78A 5cu6A-3uf6A:
undetectable		 5cu6A-3uf6A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x0y DSZC

(Rhodococcus
erythropolis) 		PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
PF08028
(Acyl-CoA_dh_2) 		4 TYR A 153
ILE A 192
VAL A 230
ALA A 190
 None
 0.92A 5cu6A-3x0yA:
undetectable		 5cu6A-3x0yA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1b LACCASE

(Lentinus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 147
ASP A 149
PRO A 150
ALA A 124
 None
 0.80A 5cu6A-3x1bA:
undetectable		 5cu6A-3x1bA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bbm CYCLIN-DEPENDENT
KINASE-LIKE 2

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR A 179
VAL A 183
PRO A 272
ALA A 169
 None
 0.80A 5cu6A-4bbmA:
25.6		 5cu6A-4bbmA:
28.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bc7 ALKYLDIHYDROXYACETON
EPHOSPHATE SYNTHASE,
PEROXISOMAL

(Cavia porcellus) 		PF01565
(FAD_binding_4)
PF02913
(FAD-oxidase_C) 		4 TYR A 296
ILE A 379
VAL A 269
ALA A 276
 None
 0.82A 5cu6A-4bc7A:
undetectable		 5cu6A-4bc7A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e2u PHO RADA INTEIN

(Pyrococcus
horikoshii) 		PF14890
(Intein_splicing) 		4 TYR A  10
ILE A 156
VAL A  48
ALA A  65
 None
 0.88A 5cu6A-4e2uA:
undetectable		 5cu6A-4e2uA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f55 SPORE CORTEX-LYTIC
ENZYME

(Bacillus cereus) 		PF07486
(Hydrolase_2) 		5 TYR A 232
ILE A 249
VAL A 172
PRO A 225
ALA A 229
 PO4  A 302 (-4.5A)
None
None
None
None
 0.99A 5cu6A-4f55A:
undetectable		 5cu6A-4f55A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fet SPORE CORTEX-LYTIC
ENZYME PREPEPTIDE

(Bacillus
anthracis) 		no annotation 5 TYR B 226
ILE B 243
VAL B 166
PRO B 219
ALA B 223
 None
 0.96A 5cu6A-4fetB:
undetectable		 5cu6A-4fetB:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fie SERINE/THREONINE-PRO
TEIN KINASE PAK 4

(Homo sapiens) 		PF00069
(Pkinase)
PF00786
(PBD) 		4 TYR A 492
VAL A 496
PRO A 557
ALA A 483
 SEP  A 474 ( 4.4A)
None
None
None
 0.81A 5cu6A-4fieA:
25.2		 5cu6A-4fieA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gak ACYL-ACP
THIOESTERASE

(Spirosoma
linguale) 		PF01643
(Acyl-ACP_TE) 		4 ILE A  65
VAL A  95
PRO A  69
ALA A 104
 None
 0.84A 5cu6A-4gakA:
undetectable		 5cu6A-4gakA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gz8 SEMAPHORIN-3A

(Mus musculus) 		PF01403
(Sema) 		4 TYR A  36
ILE A 503
VAL A  45
ALA A 510
 None
 0.86A 5cu6A-4gz8A:
undetectable		 5cu6A-4gz8A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jhv LACCASE

(Coriolopsis
caperata) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.83A 5cu6A-4jhvA:
undetectable		 5cu6A-4jhvA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k6l PUTATIVE
PERTUSSIS-LIKE TOXIN
SUBUNIT

(Salmonella
enterica) 		PF02918
(Pertussis_S2S3) 		4 TYR A  34
ILE A  55
VAL A 103
ALA A  69
 None
 0.81A 5cu6A-4k6lA:
undetectable		 5cu6A-4k6lA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ll1 THIOREDOXIN-INTERACT
ING PROTEIN

(Homo sapiens) 		PF00339
(Arrestin_N)
PF02752
(Arrestin_C) 		4 ILE A 278
VAL A 237
PRO A 211
ALA A 213
 None
 0.89A 5cu6A-4ll1A:
undetectable		 5cu6A-4ll1A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m85 N-ACETYLTRANSFERASE

(Staphylococcus
aureus) 		PF00583
(Acetyltransf_1) 		4 TYR A  18
ILE A  94
VAL A  29
PRO A 100
 None
 0.93A 5cu6A-4m85A:
undetectable		 5cu6A-4m85A:
19.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4md8 CASEIN KINASE II
SUBUNIT ALPHA

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR E  39
ILE E  69
VAL E 101
ALA E 110
 None
 0.22A 5cu6A-4md8E:
50.0		 5cu6A-4md8E:
98.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qpp PROTEIN ARGININE
N-METHYLTRANSFERASE
6

(Homo sapiens) 		PF13649
(Methyltransf_25) 		4 TYR A 159
ILE A 290
VAL A 238
ALA A 321
 None
 0.93A 5cu6A-4qppA:
undetectable		 5cu6A-4qppA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r0k DIPEPTIDYL-PEPTIDASE
VI

(Bacteroides
thetaiotaomicron) 		PF00877
(NLPC_P60) 		4 ILE A 232
VAL A 247
ASP A 245
ALA A 303
 None
 0.74A 5cu6A-4r0kA:
undetectable		 5cu6A-4r0kA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xbr PROTEIN
FAM212A,SERINE/THREO
NINE-PROTEIN KINASE
PAK 4

(Homo sapiens) 		PF00069
(Pkinase)
PF15342
(FAM212) 		4 TYR A 492
VAL A 496
PRO A 557
ALA A 483
 SEP  A 474 ( 4.2A)
None
None
None
 0.82A 5cu6A-4xbrA:
24.9		 5cu6A-4xbrA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xg1 DIAMINOPIMELATE
DECARBOXYLASE

(Psychromonas
ingrahamii) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 ILE A 134
VAL A 143
PRO A 146
ALA A 138
 None
 0.89A 5cu6A-4xg1A:
undetectable		 5cu6A-4xg1A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yxt POLYKETIDE
BIOSYNTHESIS
3-HYDROXY-3-METHYLGL
UTARYL-ACP SYNTHASE
PKSG

(Bacillus
subtilis) 		PF01154
(HMG_CoA_synt_N)
PF08540
(HMG_CoA_synt_C) 		4 ILE A 394
VAL A  44
PRO A  47
ALA A  16
 None
 0.85A 5cu6A-4yxtA:
undetectable		 5cu6A-4yxtA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bqs 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3

(Streptococcus
pneumoniae) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 TYR A 277
ILE A  45
VAL A  13
ASP A 159
 None
 0.78A 5cu6A-5bqsA:
undetectable		 5cu6A-5bqsA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cd6 TPR-DOMAIN
CONTAINING PROTEIN

(Parabacteroides
distasonis) 		PF17128
(DUF5107) 		4 TYR A 349
ILE A 277
VAL A 260
ALA A 262
 None
 0.91A 5cu6A-5cd6A:
undetectable		 5cu6A-5cd6A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ehf LACCASE

(Antrodiella
faginea) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.74A 5cu6A-5ehfA:
undetectable		 5cu6A-5ehfA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32

(Mycobacterium
marinum) 		PF00501
(AMP-binding) 		4 TYR A 610
VAL A 551
PRO A 594
ALA A 516
 None
 0.90A 5cu6A-5ey9A:
undetectable		 5cu6A-5ey9A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5inf CARBOXYL TRANSFERASE

(Streptomyces
ambofaciens) 		PF01039
(Carboxyl_trans) 		4 TYR A 487
ILE A 413
VAL A 498
ALA A 437
 None
 0.84A 5cu6A-5infA:
undetectable		 5cu6A-5infA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mew LACCASE 2

(Steccherinum
murashkinskyi) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 127
ASP A 129
PRO A 130
ALA A 104
 None
 0.82A 5cu6A-5mewA:
undetectable		 5cu6A-5mewA:
19.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mov CASEIN KINASE II
SUBUNIT ALPHA

(Homo sapiens) 		PF00069
(Pkinase) 		6 TYR A  39
ILE A  69
VAL A 101
ASP A 103
PRO A 104
ALA A 110
 None
 0.22A 5cu6A-5movA:
52.2		 5cu6A-5movA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ulu CADHERIN-23

(Mus musculus) 		no annotation 4 TYR A1941
ILE A2034
VAL A1957
ALA A1943
 None
 0.93A 5cu6A-5uluA:
undetectable		 5cu6A-5uluA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uz5 U1 SMALL NUCLEAR
RIBONUCLEOPROTEIN
COMPONENT PRP42

(Saccharomyces
cerevisiae) 		no annotation 4 TYR D 316
ILE D 321
VAL D 333
ALA D 330
 None
 0.83A 5cu6A-5uz5D:
undetectable		 5cu6A-5uz5D:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w0g SPLICING FACTOR U2AF
65 KDA SUBUNIT

(Homo sapiens) 		no annotation 4 ILE A 191
VAL A 153
PRO A 157
ALA A 198
 None
 0.57A 5cu6A-5w0gA:
undetectable		 5cu6A-5w0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w1e PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Streptomyces
coelicolor) 		no annotation 4 VAL A 223
ASP A 225
PRO A 226
ALA A 232
 None
 0.65A 5cu6A-5w1eA:
undetectable		 5cu6A-5w1eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wht PUTATIVE
PERTUSSIS-LIKE TOXIN
SUBUNIT

(Salmonella
enterica) 		no annotation 4 TYR A  34
ILE A  55
VAL A 103
ALA A  69
 SIA  A 201 ( 4.2A)
None
None
None
 0.90A 5cu6A-5whtA:
undetectable		 5cu6A-5whtA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6en4 SPLICING FACTOR 3B
SUBUNIT 3

(Homo sapiens) 		no annotation 4 TYR A 926
ILE A 800
VAL A 909
ALA A 888
 None
 0.85A 5cu6A-6en4A:
undetectable		 5cu6A-6en4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fdy -

(-) 		no annotation 4 TYR U 190
VAL U 194
PRO U 255
ALA U 181
 None
 0.84A 5cu6A-6fdyU:
24.0		 5cu6A-6fdyU:
undetectable