SIMILAR PATTERNS OF AMINO ACIDS FOR 5CR1_A_T44A201_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aor ALDEHYDE FERREDOXIN
OXIDOREDUCTASE

(Pyrococcus
furiosus) 		PF01314
(AFOR_C)
PF02730
(AFOR_N) 		4 LEU A 510
ALA A 513
LEU A 509
VAL A 209
 None
 1.17A 5cr1A-1aorA:
0.0		 5cr1A-1aorA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ap0 MODIFIER PROTEIN 1

(Mus musculus) 		PF00385
(Chromo) 		4 LYS A  25
LEU A  27
LEU A  39
VAL A  22
 None
 0.93A 5cr1A-1ap0A:
undetectable		 5cr1A-1ap0A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Salmonella
enterica) 		PF00496
(SBP_bac_5) 		4 LEU A 449
ALA A 467
LEU A 465
VAL A 328
 None
 1.02A 5cr1A-1b2hA:
0.0		 5cr1A-1b2hA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b6r PROTEIN
(N5-CARBOXYAMINOIMID
AZOLE RIBONUCLEOTIDE
SYNTHETASE)

(Escherichia
coli) 		PF02222
(ATP-grasp) 		4 LEU A 210
ALA A 224
LEU A 164
VAL A 243
 None
 1.20A 5cr1A-1b6rA:
0.0		 5cr1A-1b6rA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)

(Escherichia
coli) 		PF00549
(Ligase_CoA)
PF08442
(ATP-grasp_2) 		4 LEU B 201
ALA B 125
LEU B 108
VAL B 147
 None
 1.17A 5cr1A-1cqiB:
0.0		 5cr1A-1cqiB:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ctm CYTOCHROME F

(Brassica rapa) 		PF01333
(Apocytochr_F_C)
PF16639
(Apocytochr_F_N) 		4 LEU A  75
ALA A  73
LEU A 113
VAL A  71
 None
None
None
HEM  A 253 (-4.9A)
 0.89A 5cr1A-1ctmA:
0.0		 5cr1A-1ctmA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eb3 5-AMINOLAEVULINIC
ACID DEHYDRATASE

(Saccharomyces
cerevisiae) 		PF00490
(ALAD) 		4 LYS A  81
LEU A  78
ALA A  80
LEU A  75
 None
 1.03A 5cr1A-1eb3A:
undetectable		 5cr1A-1eb3A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f5a POLY(A) POLYMERASE

(Bos taurus) 		PF01909
(NTP_transf_2)
PF04926
(PAP_RNA-bind)
PF04928
(PAP_central) 		4 LEU A 173
ALA A 120
LEU A 175
VAL A  72
 None
 1.01A 5cr1A-1f5aA:
0.2		 5cr1A-1f5aA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fno PEPTIDASE T

(Salmonella
enterica) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 LYS A 406
LEU A 403
ALA A 405
VAL A  66
 None
 1.05A 5cr1A-1fnoA:
0.0		 5cr1A-1fnoA:
15.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gke TRANSTHYRETIN

(Rattus
norvegicus) 		PF00576
(Transthyretin) 		5 LYS A  15
LEU A  17
ALA A 108
LEU A 110
VAL A 121
 None
 0.62A 5cr1A-1gkeA:
21.9		 5cr1A-1gkeA:
83.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jnf SEROTRANSFERRIN

(Oryctolagus
cuniculus) 		PF00405
(Transferrin) 		4 LEU A  66
ALA A  64
LEU A  62
VAL A 246
 None
 1.13A 5cr1A-1jnfA:
undetectable		 5cr1A-1jnfA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mab PROTEIN (F1-ATPASE
BETA CHAIN)

(Rattus
norvegicus) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 LYS B 175
ALA B 174
LEU B 169
VAL B 215
 None
 1.00A 5cr1A-1mabB:
undetectable		 5cr1A-1mabB:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oh2 SUCROSE SPECIFIC
PORIN

(Salmonella
enterica) 		PF02264
(LamB) 		4 LEU Q 292
ALA Q 290
LEU Q 311
VAL Q 288
 None
 1.12A 5cr1A-1oh2Q:
undetectable		 5cr1A-1oh2Q:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)

(Homo sapiens) 		PF03810
(IBN_N)
PF13513
(HEAT_EZ) 		4 LEU A 821
ALA A 768
LEU A 766
VAL A 735
 None
 1.19A 5cr1A-1qgrA:
undetectable		 5cr1A-1qgrA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rj6 CARBONIC ANHYDRASE
XIV

(Mus musculus) 		PF00194
(Carb_anhydrase) 		4 LEU A  95
ALA A 116
LEU A 118
VAL A 150
 None
 1.19A 5cr1A-1rj6A:
undetectable		 5cr1A-1rj6A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ryo SEROTRANSFERRIN

(Homo sapiens) 		PF00405
(Transferrin) 		4 LEU A  66
ALA A  64
LEU A  62
VAL A 246
 None
 1.18A 5cr1A-1ryoA:
undetectable		 5cr1A-1ryoA:
15.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sn2 TRANSTHYRETIN

(Sparus aurata) 		PF00576
(Transthyretin) 		5 LYS A  15
LEU A  17
ALA A 108
LEU A 110
VAL A 121
 None
 0.45A 5cr1A-1sn2A:
20.7		 5cr1A-1sn2A:
57.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tfp TRANSTHYRETIN

(Gallus gallus) 		PF00576
(Transthyretin) 		5 LYS A  15
LEU A  17
ALA A 108
LEU A 110
VAL A 121
 None
 0.44A 5cr1A-1tfpA:
19.7		 5cr1A-1tfpA:
78.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ven BETA-AMYLASE

(Bacillus cereus) 		PF00686
(CBM_20)
PF01373
(Glyco_hydro_14) 		4 LEU A 395
ALA A  13
LEU A  15
VAL A 417
 None
 0.95A 5cr1A-1venA:
undetectable		 5cr1A-1venA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wy6 HYPOTHETICAL PROTEIN
ST1625

(Sulfurisphaera
tokodaii) 		PF09205
(DUF1955) 		4 LEU A 148
ALA A 131
LEU A 129
VAL A  95
 None
 1.08A 5cr1A-1wy6A:
undetectable		 5cr1A-1wy6A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xmb IAA-AMINO ACID
HYDROLASE HOMOLOG 2

(Arabidopsis
thaliana) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 LYS A  43
LEU A  39
ALA A  42
LEU A  38
 None
 1.07A 5cr1A-1xmbA:
undetectable		 5cr1A-1xmbA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yg8 ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT

(Escherichia
coli) 		PF00574
(CLP_protease) 		4 LEU A 152
ALA A 105
LEU A 155
VAL A  87
 None
 1.17A 5cr1A-1yg8A:
undetectable		 5cr1A-1yg8A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zpv ACT DOMAIN PROTEIN

(Streptococcus
pneumoniae) 		PF13740
(ACT_6) 		4 LYS A  22
LEU A  26
LEU A  28
VAL A   7
 None
 1.10A 5cr1A-1zpvA:
undetectable		 5cr1A-1zpvA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zzg GLUCOSE-6-PHOSPHATE
ISOMERASE

(Thermus
thermophilus) 		PF00342
(PGI) 		4 LEU A 236
ALA A 309
LEU A 235
VAL A 311
 None
 1.20A 5cr1A-1zzgA:
undetectable		 5cr1A-1zzgA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d04 CURCULIN
NEOCULIN ACIDIC
SUBUNIT

(Molineria
latifolia) 		PF01453
(B_lectin) 		4 LEU A  56
ALA A  85
LEU A   4
VAL B  95
 None
 1.10A 5cr1A-2d04A:
undetectable		 5cr1A-2d04A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d04 CURCULIN
NEOCULIN ACIDIC
SUBUNIT

(Molineria
latifolia) 		PF01453
(B_lectin) 		4 LEU B  56
ALA B  85
LEU B   4
VAL A  95
 None
 1.12A 5cr1A-2d04B:
undetectable		 5cr1A-2d04B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2elc ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE

(Thermus
thermophilus) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N) 		4 LEU A  89
ALA A 286
LEU A  92
VAL A 304
 None
 1.21A 5cr1A-2elcA:
undetectable		 5cr1A-2elcA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gfp MULTIDRUG RESISTANCE
PROTEIN D

(Escherichia
coli) 		PF07690
(MFS_1) 		4 LEU A  16
ALA A  18
LEU A 169
VAL A 143
 None
 1.12A 5cr1A-2gfpA:
undetectable		 5cr1A-2gfpA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hqm GLUTATHIONE
REDUCTASE

(Saccharomyces
cerevisiae) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 352
ALA A  42
LEU A 356
VAL A 132
 None
 1.11A 5cr1A-2hqmA:
undetectable		 5cr1A-2hqmA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ill TITIN

(Homo sapiens) 		PF07679
(I-set) 		4 LEU A  12
ALA A  90
LEU A  92
VAL A  77
 None
 0.96A 5cr1A-2illA:
undetectable		 5cr1A-2illA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jxm CYTOCHROME F

(Prochlorothrix
hollandica) 		PF01333
(Apocytochr_F_C)
PF16639
(Apocytochr_F_N) 		4 LEU B  75
ALA B  73
LEU B 115
VAL B  71
 None
None
None
HEC  B 250 (-4.1A)
 1.04A 5cr1A-2jxmB:
undetectable		 5cr1A-2jxmB:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nck NUCLEOSIDE
DIPHOSPHATE KINASE

(Myxococcus
xanthus) 		no annotation 4 LYS R 126
LEU R 122
ALA R 125
VAL R  76
 None
 1.19A 5cr1A-2nckR:
undetectable		 5cr1A-2nckR:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nzi TITIN

(Homo sapiens) 		PF00041
(fn3)
PF07679
(I-set) 		4 LEU A  11
ALA A  89
LEU A  91
VAL A  76
 None
 1.00A 5cr1A-2nziA:
2.7		 5cr1A-2nziA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2obx 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
1

(Mesorhizobium
loti) 		PF00885
(DMRL_synthase) 		4 LEU A 111
ALA A  73
LEU A  75
VAL A  12
 None
 0.86A 5cr1A-2obxA:
undetectable		 5cr1A-2obxA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q3z TRANSGLUTAMINASE 2

(Homo sapiens) 		PF00868
(Transglut_N)
PF00927
(Transglut_C)
PF01841
(Transglut_core) 		4 LEU A 567
ALA A 565
LEU A 576
VAL A 563
 None
 1.12A 5cr1A-2q3zA:
undetectable		 5cr1A-2q3zA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rdy BH0842 PROTEIN

(Bacillus
halodurans) 		PF14498
(Glyco_hyd_65N_2) 		4 LEU A  98
ALA A 163
LEU A 165
VAL A 236
 None
 0.91A 5cr1A-2rdyA:
undetectable		 5cr1A-2rdyA:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x4d PHOSPHOLYSINE
PHOSPHOHISTIDINE
INORGANIC
PYROPHOSPHATE
PHOSPHATASE

(Homo sapiens) 		PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6) 		4 LYS A 183
ALA A 184
LEU A 176
VAL A 186
 None
EPE  A 502 (-3.9A)
None
None
 1.08A 5cr1A-2x4dA:
undetectable		 5cr1A-2x4dA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ych COMPETENCE PROTEIN
PILM

(Thermus
thermophilus) 		PF11104
(PilM_2) 		4 LEU A  27
ALA A 369
LEU A  18
VAL A 373
 None
 1.20A 5cr1A-2ychA:
undetectable		 5cr1A-2ychA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yr3 MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE

(Homo sapiens) 		PF07679
(I-set) 		4 LEU A  66
ALA A  64
LEU A  31
VAL A  35
 None
 1.11A 5cr1A-2yr3A:
undetectable		 5cr1A-2yr3A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yx0 RADICAL SAM ENZYME

(Pyrococcus
horikoshii) 		PF04055
(Radical_SAM)
PF08608
(Wyosine_form) 		4 LYS A 263
ALA A 264
LEU A 231
VAL A 241
 None
 1.07A 5cr1A-2yx0A:
undetectable		 5cr1A-2yx0A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afl OLIGO ALGINATE LYASE

(Agrobacterium
fabrum) 		PF07940
(Hepar_II_III)
PF16332
(DUF4962) 		4 LEU A 730
ALA A 720
LEU A 655
VAL A 718
 None
 1.17A 5cr1A-3aflA:
3.2		 5cr1A-3aflA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqp PROBABLE SECDF
PROTEIN-EXPORT
MEMBRANE PROTEIN

(Thermus
thermophilus) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG) 		4 LEU A 208
ALA A 111
LEU A 113
VAL A 252
 None
 1.12A 5cr1A-3aqpA:
undetectable		 5cr1A-3aqpA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cwr TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Rhodospirillum
rubrum) 		PF00440
(TetR_N) 		4 LEU A 174
ALA A 106
LEU A 102
VAL A  68
 None
 1.07A 5cr1A-3cwrA:
undetectable		 5cr1A-3cwrA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d43 SPHERICASE

(Lysinibacillus
sphaericus) 		PF00082
(Peptidase_S8) 		4 LEU A 275
ALA A 261
LEU A 162
VAL A  93
 None
 1.20A 5cr1A-3d43A:
undetectable		 5cr1A-3d43A:
19.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fc8 TRANSTHYRETIN

(Homo sapiens) 		PF00576
(Transthyretin) 		5 LYS A  15
LEU A  17
ALA A 108
LEU A 110
VAL A 121
 IFA  A3000 (-3.0A)
IFA  A3000 ( 4.7A)
IFA  A3000 (-3.1A)
IFA  A3000 (-4.1A)
None
 0.78A 5cr1A-3fc8A:
24.2		 5cr1A-3fc8A:
99.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gz5 MUTT/NUDIX FAMILY
PROTEIN

(Shewanella
oneidensis) 		PF00293
(NUDIX) 		4 LEU A  26
ALA A  24
LEU A  37
VAL A  22
 None
 1.11A 5cr1A-3gz5A:
undetectable		 5cr1A-3gz5A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h8t HMUY

(Porphyromonas
gingivalis) 		PF14064
(HmuY) 		4 LYS A 177
LEU A 175
LEU A 162
VAL A 192
 None
 1.11A 5cr1A-3h8tA:
undetectable		 5cr1A-3h8tA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hqi SPECKLE-TYPE POZ
PROTEIN

(Homo sapiens) 		PF00651
(BTB)
PF00917
(MATH) 		4 LEU A 308
ALA A 275
LEU A 311
VAL A 246
 None
 1.20A 5cr1A-3hqiA:
undetectable		 5cr1A-3hqiA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvs THIOL PEROXIDASE

(Escherichia
coli) 		PF08534
(Redoxin) 		4 LEU A 127
ALA A 132
LEU A 130
VAL A 150
 None
 1.21A 5cr1A-3hvsA:
undetectable		 5cr1A-3hvsA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mez MANNOSE-SPECIFIC
LECTIN 3 CHAIN 1
MANNOSE-SPECIFIC
LECTIN 3 CHAIN 2

(Crocus vernus) 		PF01453
(B_lectin) 		4 LEU A  56
ALA A  88
LEU A   5
VAL B 102
 None
 1.12A 5cr1A-3mezA:
undetectable		 5cr1A-3mezA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3msv NUCLEAR IMPORT
ADAPTOR, NRO1

(Schizosaccharomyces
pombe) 		PF12753
(Nro1) 		4 LEU A  69
ALA A 123
LEU A  72
VAL A 127
 None
 1.20A 5cr1A-3msvA:
undetectable		 5cr1A-3msvA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nip 3-GUANIDINOPROPIONAS
E

(Pseudomonas
aeruginosa) 		PF00491
(Arginase) 		4 LEU A 309
ALA A 311
LEU A 277
VAL A  85
 None
 1.20A 5cr1A-3nipA:
undetectable		 5cr1A-3nipA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qac 11S GLOBULIN SEED
STORAGE PROTEIN

(Amaranthus
hypochondriacus) 		PF00190
(Cupin_1) 		4 LEU A 318
ALA A 325
LEU A 323
VAL A 398
 None
 1.21A 5cr1A-3qacA:
undetectable		 5cr1A-3qacA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3si9 DIHYDRODIPICOLINATE
SYNTHASE

(Bartonella
henselae) 		PF00701
(DHDPS) 		4 LEU A 264
ALA A 260
LEU A 266
VAL A 248
 None
 0.91A 5cr1A-3si9A:
undetectable		 5cr1A-3si9A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3toy MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY PROTEIN

(Bradyrhizobium
sp. ORS 278) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A  51
ALA A  11
LEU A  62
VAL A   9
 None
 1.13A 5cr1A-3toyA:
undetectable		 5cr1A-3toyA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ubm FORMYL-COA:OXALATE
COA-TRANSFERASE

(Acetobacter
aceti) 		PF02515
(CoA_transf_3) 		4 LEU A 226
ALA A 222
LEU A 186
VAL A 217
 None
 1.10A 5cr1A-3ubmA:
undetectable		 5cr1A-3ubmA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uk2 PANTOTHENATE
SYNTHETASE

(Burkholderia
thailandensis) 		PF02569
(Pantoate_ligase) 		4 LEU A 268
ALA A 266
LEU A 273
VAL A 238
 None
 0.98A 5cr1A-3uk2A:
undetectable		 5cr1A-3uk2A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ul4 CELLULOSOME ENZYME,
DOCKERIN TYPE I
CELLULOSOME-ANCHORIN
G PROTEIN

(Ruminiclostridium
thermocellum) 		PF00404
(Dockerin_1)
PF00963
(Cohesin) 		4 LEU B  26
ALA A  81
LEU A  83
VAL A  74
 None
None
None
SO4  A 158 (-4.0A)
 1.05A 5cr1A-3ul4B:
undetectable		 5cr1A-3ul4B:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN

(Burkholderia
thailandensis) 		PF00359
(PTS_EIIA_2) 		4 LEU A 104
ALA A  79
LEU A  77
VAL A  14
 None
 0.69A 5cr1A-3urrA:
undetectable		 5cr1A-3urrA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3urr PTS IIA-LIKE
NITROGEN-REGULATORY
PROTEIN PTSN

(Burkholderia
thailandensis) 		PF00359
(PTS_EIIA_2) 		4 LEU A 104
ALA A  79
LEU A  77
VAL A  81
 None
 1.18A 5cr1A-3urrA:
undetectable		 5cr1A-3urrA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w5i FERROUS IRON
TRANSPORT PROTEIN B

(Gallionella
capsiferriformans) 		PF02421
(FeoB_N) 		4 LEU A  84
ALA A   5
LEU A  82
VAL A  71
 None
 1.11A 5cr1A-3w5iA:
undetectable		 5cr1A-3w5iA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Burkholderia
pseudomallei) 		PF00496
(SBP_bac_5) 		4 LEU A 151
ALA A 197
LEU A 201
VAL A  95
 None
 1.14A 5cr1A-3zs6A:
undetectable		 5cr1A-3zs6A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b90 DIHYDROPYRIMIDINASE-
RELATED PROTEIN 5

(Homo sapiens) 		PF01979
(Amidohydro_1) 		4 LEU A 278
ALA A 276
LEU A 300
VAL A 322
 None
 1.12A 5cr1A-4b90A:
undetectable		 5cr1A-4b90A:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b92 DIHYDROPYRIMIDINASE-
RELATED PROTEIN 5

(Homo sapiens) 		PF01979
(Amidohydro_1) 		4 LEU A 278
ALA A 276
LEU A 300
VAL A 322
 None
 1.14A 5cr1A-4b92A:
undetectable		 5cr1A-4b92A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c51 CATALASE-PEROXIDASE

(Mycobacterium
tuberculosis) 		PF00141
(peroxidase) 		4 LYS A 613
LEU A 617
LEU A 619
VAL A 694
 None
 0.82A 5cr1A-4c51A:
undetectable		 5cr1A-4c51A:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dmg PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493

(Thermus
thermophilus) 		PF02475
(Met_10) 		4 LEU A 259
ALA A 255
LEU A 261
VAL A 225
 None
 1.04A 5cr1A-4dmgA:
undetectable		 5cr1A-4dmgA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i7z APOCYTOCHROME F

(Mastigocladus
laminosus) 		PF01333
(Apocytochr_F_C)
PF16639
(Apocytochr_F_N) 		4 LEU C  76
ALA C  74
LEU C 114
VAL C  72
 None
HEM  C 301 (-4.8A)
None
HEM  C 301 (-4.9A)
 0.97A 5cr1A-4i7zC:
undetectable		 5cr1A-4i7zC:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j57 THIOREDOXIN
REDUCTASE 2

(Plasmodium
falciparum) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 376
ALA A  60
LEU A 380
VAL A 154
 None
 1.16A 5cr1A-4j57A:
undetectable		 5cr1A-4j57A:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jnh GAG POLYPROTEIN

(Simian foamy
virus) 		PF03276
(Gag_spuma) 		4 LEU A 100
ALA A  96
LEU A  93
VAL A  14
 None
 1.19A 5cr1A-4jnhA:
undetectable		 5cr1A-4jnhA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC

(Rattus
norvegicus) 		no annotation 4 LEU E 353
ALA E  31
LEU E 357
VAL E 125
 None
 1.15A 5cr1A-4kprE:
undetectable		 5cr1A-4kprE:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kqx KETOL-ACID
REDUCTOISOMERASE

(Slackia exigua) 		PF01450
(IlvC)
PF07991
(IlvN) 		4 LYS A 191
LEU A  15
ALA A 161
VAL A 163
 None
 1.10A 5cr1A-4kqxA:
undetectable		 5cr1A-4kqxA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC

(Solanum
lycopersicum) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 LYS A 448
LEU A 477
LEU A 540
VAL A 391
 None
 1.20A 5cr1A-4ksiA:
undetectable		 5cr1A-4ksiA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o99 ACETYL-COA
ACETYLTRANSFERASE

(Cupriavidus
necator) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 LYS A 264
LEU A 268
LEU A 270
VAL A   4
 None
 1.10A 5cr1A-4o99A:
undetectable		 5cr1A-4o99A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4omj SEC14-LIKE PROTEIN 2

(Homo sapiens) 		PF00650
(CRAL_TRIO) 		4 LEU A 158
ALA A 194
LEU A 197
VAL A 219
 2TX  A 310 ( 4.4A)
None
None
None
 1.19A 5cr1A-4omjA:
undetectable		 5cr1A-4omjA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4opw UNCHARACTERIZED
PROTEIN

(Parabacteroides
merdae) 		PF10988
(DUF2807) 		4 LEU A 166
ALA A 188
LEU A 151
VAL A 211
 None
 1.00A 5cr1A-4opwA:
undetectable		 5cr1A-4opwA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q66 PROTEIN BCH1

(Saccharomyces
cerevisiae) 		no annotation 4 LYS K 370
ALA K 373
LEU K 360
VAL K 377
 None
 1.17A 5cr1A-4q66K:
undetectable		 5cr1A-4q66K:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rg8 EXONUCLEASE I

(Methylocaldum
szegediense) 		PF00929
(RNase_T)
PF08411
(Exonuc_X-T_C) 		4 LEU A 312
ALA A 307
LEU A 309
VAL A 305
 None
 1.09A 5cr1A-4rg8A:
undetectable		 5cr1A-4rg8A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhc ALPHA-L-RHAMNOSIDASE

(Klebsiella
oxytoca) 		PF17389
(Bac_rhamnosid6H) 		4 LYS A 347
LEU A 345
ALA A 350
VAL A 354
 None
 1.17A 5cr1A-4xhcA:
undetectable		 5cr1A-4xhcA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xvx ACYL-[ACYL-CARRIER-P
ROTEIN]
DEHYDROGENASE MBTN

(Mycobacterium
tuberculosis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 LYS A 312
LEU A 362
ALA A 308
LEU A 365
 None
 1.03A 5cr1A-4xvxA:
undetectable		 5cr1A-4xvxA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aby EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-3

(Caenorhabditis
elegans) 		PF01652
(IF4E) 		4 LEU A 185
ALA A 134
LEU A 181
VAL A 136
 None
 1.00A 5cr1A-5abyA:
undetectable		 5cr1A-5abyA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b1h CYSTATHIONINE
BETA-SYNTHASE

(Lactobacillus
plantarum) 		PF00291
(PALP) 		4 LEU A 272
ALA A 270
LEU A 268
VAL A 198
 None
 1.21A 5cr1A-5b1hA:
undetectable		 5cr1A-5b1hA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dot CARBAMOYL-PHOSPHATE
SYNTHASE [AMMONIA],
MITOCHONDRIAL

(Homo sapiens) 		PF00117
(GATase)
PF00988
(CPSase_sm_chain)
PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		4 LEU A1347
ALA A1345
LEU A1488
VAL A1306
 None
 1.09A 5cr1A-5dotA:
undetectable		 5cr1A-5dotA:
6.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus sp.
(in: Bacteria)) 		PF00082
(Peptidase_S8) 		4 LEU A 276
ALA A 262
LEU A 163
VAL A  94
 None
 1.20A 5cr1A-5ffnA:
undetectable		 5cr1A-5ffnA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g26 INTIMIN

(Escherichia
coli) 		PF11924
(IAT_beta) 		4 LEU A 338
ALA A 346
LEU A 344
VAL A 375
 None
 0.90A 5cr1A-5g26A:
undetectable		 5cr1A-5g26A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gxu NADPH--CYTOCHROME
P450 REDUCTASE 2

(Arabidopsis
thaliana) 		PF00175
(NAD_binding_1)
PF00258
(Flavodoxin_1)
PF00667
(FAD_binding_1) 		4 LEU A 438
ALA A 424
LEU A 422
VAL A 477
 None
 1.18A 5cr1A-5gxuA:
undetectable		 5cr1A-5gxuA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjr GENOME POLYPROTEIN

(Dengue virus) 		PF00972
(Flavi_NS5)
PF01728
(FtsJ) 		4 LYS A 747
ALA A 752
LEU A 754
VAL A 870
 None
 1.20A 5cr1A-5jjrA:
undetectable		 5cr1A-5jjrA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kqi CATALASE-PEROXIDASE

(Burkholderia
pseudomallei) 		PF00141
(peroxidase) 		4 LYS A 620
LEU A 624
LEU A 626
VAL A 702
 None
 0.88A 5cr1A-5kqiA:
undetectable		 5cr1A-5kqiA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lki TCDA1

(Photorhabdus
luminescens) 		PF03538
(VRP1) 		4 LEU A2433
ALA A2431
LEU A2448
VAL A2429
 None
 1.20A 5cr1A-5lkiA:
undetectable		 5cr1A-5lkiA:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4l CERULOPLASMIN

(Rattus
norvegicus) 		no annotation 4 LYS A 656
LEU A 658
LEU A 621
VAL A 630
 None
 1.12A 5cr1A-5n4lA:
undetectable		 5cr1A-5n4lA:
26.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n7s TYPE II SECRETION
SYSTEM PROTEIN L

(Pseudomonas
aeruginosa) 		no annotation 4 LEU B 378
ALA B 376
LEU B 338
VAL B 374
 None
 1.05A 5cr1A-5n7sB:
undetectable		 5cr1A-5n7sB:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tx7 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE FAMILY
PROTEIN

(Desulfovibrio
vulgaris) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 LEU A 109
ALA A 258
LEU A 281
VAL A 246
 None
 1.01A 5cr1A-5tx7A:
undetectable		 5cr1A-5tx7A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ucr PANTOTHENATE
SYNTHETASE

(Neisseria
gonorrhoeae) 		PF02569
(Pantoate_ligase) 		4 LEU A 264
ALA A 262
LEU A 269
VAL A 238
 None
 1.07A 5cr1A-5ucrA:
undetectable		 5cr1A-5ucrA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v36 GLUTATHIONE
REDUCTASE

(Streptococcus
mutans) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 321
ALA A  23
LEU A 325
VAL A 108
 None
 1.17A 5cr1A-5v36A:
undetectable		 5cr1A-5v36A:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wml -

(-) 		no annotation 4 LEU A 177
ALA A 175
LEU A 331
VAL A 301
 None
 1.01A 5cr1A-5wmlA:
undetectable		 5cr1A-5wmlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zal ENDORIBONUCLEASE
DICER

(Homo sapiens) 		no annotation 4 LEU A1704
ALA A1816
LEU A1707
VAL A1833
 None
 1.14A 5cr1A-5zalA:
undetectable		 5cr1A-5zalA:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b92 U6 SMALL NUCLEAR RNA
(ADENINE-(43)-N(6))-
METHYLTRANSFERASE

(Homo sapiens) 		no annotation 4 LEU A 166
ALA A 169
LEU A 165
VAL A 158
 None
None
SAH  A 305 ( 4.6A)
None
 1.15A 5cr1A-6b92A:
undetectable		 5cr1A-6b92A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bn2 ACETYL-COA
ACETYLTRANSFERASE

(Elizabethkingia
anophelis) 		no annotation 4 LYS A 263
LEU A 267
LEU A 269
VAL A 102
 None
 1.18A 5cr1A-6bn2A:
undetectable		 5cr1A-6bn2A:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btm ALTERNATIVE COMPLEX
III SUBUNIT B

(Flavobacterium
johnsoniae) 		no annotation 4 LEU B 519
ALA B  96
LEU B 470
VAL B 110
 None
 1.21A 5cr1A-6btmB:
undetectable		 5cr1A-6btmB:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ccz SERINE
HYDROXYMETHYLTRANSFE
RASE

(Medicago
truncatula) 		no annotation 4 LYS A 488
LEU A 485
ALA A 487
VAL A 503
 None
 1.14A 5cr1A-6cczA:
undetectable		 5cr1A-6cczA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fd2 PUTATIVE APRAMYCIN
BIOSYNTHETIC
OXIDOREDUCTASE 4

(Streptoalloteichus
tenebrarius) 		no annotation 4 LEU B  46
ALA B  63
LEU B  11
VAL B  70
 None
 1.07A 5cr1A-6fd2B:
undetectable		 5cr1A-6fd2B:
20.47