SIMILAR PATTERNS OF AMINO ACIDS FOR 5CDP_H_EVPH2101
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b9y | PROTEIN (PHOSDUCIN) (Rattusnorvegicus) |
PF02114(Phosducin) | 4 | SER C 203GLY C 178ASP C 179ARG C 180 | None | 0.80A | 5cdpA-1b9yC:undetectable5cdpB-1b9yC:undetectable | 5cdpA-1b9yC:18.355cdpB-1b9yC:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1flg | PROTEIN(QUINOPROTEINETHANOLDEHYDROGENASE) (Pseudomonasaeruginosa) |
PF01011(PQQ)PF13360(PQQ_2) | 4 | SER A 573GLY A 505ASP A 506GLY A 503 | None | 0.97A | 5cdpA-1flgA:undetectable5cdpB-1flgA:undetectable | 5cdpA-1flgA:21.495cdpB-1flgA:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jcf | RODSHAPE-DETERMININGPROTEIN MREB (Thermotogamaritima) |
PF06723(MreB_Mbl) | 4 | GLY A 157ASP A 180ARG A 66GLY A 68 | None | 0.97A | 5cdpA-1jcfA:0.05cdpB-1jcfA:2.3 | 5cdpA-1jcfA:23.255cdpB-1jcfA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k4q | GLUTATHIONEREDUCTASE (Homo sapiens) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | SER A 51GLY A 330ASP A 331GLY A 31 | FAD A 499 (-3.1A)FAD A 499 (-3.3A)FAD A 499 (-2.9A)FAD A 499 (-3.7A) | 0.86A | 5cdpA-1k4qA:undetectable5cdpB-1k4qA:undetectable | 5cdpA-1k4qA:22.165cdpB-1k4qA:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1obb | ALPHA-GLUCOSIDASE (Thermotogamaritima) |
PF02056(Glyco_hydro_4)PF11975(Glyco_hydro_4C) | 4 | GLU A 404GLY A 259ASP A 260GLY A 179 | NoneNoneMAL A 900 (-2.8A)None | 0.95A | 5cdpA-1obbA:0.05cdpB-1obbA:undetectable | 5cdpA-1obbA:21.855cdpB-1obbA:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1obf | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Achromobacterxylosoxidans) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | GLU O 30GLY O 8ASP O 36GLY O 13 | None | 0.95A | 5cdpA-1obfO:2.55cdpB-1obfO:undetectable | 5cdpA-1obfO:20.535cdpB-1obfO:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ofc | ISWI PROTEIN (Drosophilamelanogaster) |
PF09110(HAND)PF09111(SLIDE) | 4 | SER X 871GLU X 964GLY X 816GLY X 862 | None | 0.87A | 5cdpA-1ofcX:1.55cdpB-1ofcX:undetectable | 5cdpA-1ofcX:21.065cdpB-1ofcX:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p31 | UDP-N-ACETYLMURAMATE--ALANINE LIGASE (Haemophilusinfluenzae) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 4 | SER A 177GLU A 176GLY A 25GLY A 28 | EPU A 598 (-3.1A) MG A 776 ( 4.1A)EPU A 598 (-3.5A)EPU A 598 (-3.2A) | 0.95A | 5cdpA-1p31A:0.05cdpB-1p31A:undetectable | 5cdpA-1p31A:23.775cdpB-1p31A:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pvx | PROTEIN(ENDO-1,4-BETA-XYLANASE) (Byssochlamysspectabilis) |
PF00457(Glyco_hydro_11) | 4 | SER A 16GLU A 7GLY A 43GLY A 21 | None | 0.91A | 5cdpA-1pvxA:undetectable5cdpB-1pvxA:undetectable | 5cdpA-1pvxA:16.775cdpB-1pvxA:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sfe | ADAO6-METHYLGUANINE-DNAMETHYLTRANSFERASE (Escherichiacoli) |
PF01035(DNA_binding_1)PF02870(Methyltransf_1N) | 4 | GLY A 24ASP A 20ARG A 25GLY A 41 | None | 0.97A | 5cdpA-1sfeA:undetectable5cdpB-1sfeA:undetectable | 5cdpA-1sfeA:18.455cdpB-1sfeA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1spi | FRUCTOSE1,6-BISPHOSPHATASE (Spinaciaoleracea) |
PF00316(FBPase) | 4 | GLU A 109GLY A 121ARG A 100GLY A 99 | None | 0.93A | 5cdpA-1spiA:undetectable5cdpB-1spiA:undetectable | 5cdpA-1spiA:20.205cdpB-1spiA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vcz | RNASE NGR3 (Nicotianaglutinosa) |
PF00445(Ribonuclease_T2) | 4 | SER A 154GLU A 148GLY A 192GLY A 194 | None | 0.81A | 5cdpA-1vczA:undetectable5cdpB-1vczA:undetectable | 5cdpA-1vczA:17.765cdpB-1vczA:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yna | ENDO-1,4-BETA-XYLANASE (Thermomyceslanuginosus) |
PF00457(Glyco_hydro_11) | 4 | SER A 16GLU A 7GLY A 43GLY A 21 | None | 0.87A | 5cdpA-1ynaA:undetectable5cdpB-1ynaA:undetectable | 5cdpA-1ynaA:16.775cdpB-1ynaA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ac5 | MAPKINASE-INTERACTINGSERINE/THREONINEKINASE 2 (Homo sapiens) |
PF00069(Pkinase) | 4 | GLY A 91ASP A 88ARG A 97GLY A 93 | None | 0.94A | 5cdpA-2ac5A:4.55cdpB-2ac5A:undetectable | 5cdpA-2ac5A:21.065cdpB-2ac5A:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b4e | CORONIN-1A (Mus musculus) |
PF00400(WD40)PF08953(DUF1899)PF16300(WD40_4) | 4 | SER A 31GLU A 52GLY A 286GLY A 288 | None | 0.84A | 5cdpA-2b4eA:undetectable5cdpB-2b4eA:undetectable | 5cdpA-2b4eA:24.105cdpB-2b4eA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e5v | L-ASPARTATE OXIDASE (Sulfurisphaeratokodaii) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 4 | SER A 327GLY A 190ASP A 191GLY A 173 | NoneNoneFAD A1002 (-2.9A)FAD A1002 ( 3.8A) | 0.70A | 5cdpA-2e5vA:undetectable5cdpB-2e5vA:undetectable | 5cdpA-2e5vA:22.565cdpB-2e5vA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f5v | PYRANOSE 2-OXIDASE (Peniophora sp.SG) |
PF05199(GMC_oxred_C) | 4 | GLU A 273GLY A 53ASP A 76GLY A 58 | NoneFAD A1625 (-3.4A)FAD A1625 (-2.9A)None | 0.92A | 5cdpA-2f5vA:undetectable5cdpB-2f5vA:undetectable | 5cdpA-2f5vA:20.475cdpB-2f5vA:15.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g17 | N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATEREDUCTASE (Salmonellaenterica) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 4 | GLY A 238ASP A 307ARG A 237GLY A 185 | None | 0.99A | 5cdpA-2g17A:undetectable5cdpB-2g17A:undetectable | 5cdpA-2g17A:22.295cdpB-2g17A:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h0e | TRANSTHYRETIN-LIKEPROTEIN PUCM (Bacillussubtilis) |
PF00576(Transthyretin) | 4 | GLU A 36GLY A 9ASP A 101GLY A 57 | None | 0.97A | 5cdpA-2h0eA:undetectable5cdpB-2h0eA:undetectable | 5cdpA-2h0eA:13.895cdpB-2h0eA:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2imr | HYPOTHETICAL PROTEINDR_0824 (Deinococcusradiodurans) |
PF01979(Amidohydro_1) | 4 | SER A 209GLU A 173GLY A 394GLY A 168 | None | 0.96A | 5cdpA-2imrA:undetectable5cdpB-2imrA:undetectable | 5cdpA-2imrA:22.025cdpB-2imrA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2inp | PHENOL HYDROXYLASECOMPONENT PHN (Pseudomonasstutzeri) |
PF02332(Phenol_Hydrox)PF04945(YHS) | 4 | SER A 195GLU A 199GLY A 124GLY A 126 | None FE A 1 (-2.2A)NoneNone | 0.98A | 5cdpA-2inpA:undetectable5cdpB-2inpA:undetectable | 5cdpA-2inpA:19.965cdpB-2inpA:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jjq | UNCHARACTERIZED RNAMETHYLTRANSFERASEPYRAB10780 (Pyrococcusabyssi) |
PF05958(tRNA_U5-meth_tr) | 4 | SER A 266GLU A 267ASP A 242ARG A 237 | None | 0.99A | 5cdpA-2jjqA:undetectable5cdpB-2jjqA:undetectable | 5cdpA-2jjqA:21.955cdpB-2jjqA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k20 | PARTITIONING-DEFECTIVE 3 HOMOLOG (Rattusnorvegicus) |
PF00595(PDZ) | 4 | SER A 90GLU A 94GLY A 43ASP A 41 | None | 0.98A | 5cdpA-2k20A:undetectable5cdpB-2k20A:undetectable | 5cdpA-2k20A:13.485cdpB-2k20A:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nm0 | PROBABLE3-OXACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (Streptomycescoelicolor) |
PF13561(adh_short_C2) | 4 | SER A 143GLY A 15ARG A 12GLY A 9 | None | 0.75A | 5cdpA-2nm0A:undetectable5cdpB-2nm0A:3.3 | 5cdpA-2nm0A:20.845cdpB-2nm0A:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pfx | UNCHARACTERIZEDPEROXIDASE-RELATEDPROTEIN (Ruegeria sp.TM1040) |
PF02627(CMD) | 4 | SER A 65GLU A 64ARG A 148GLY A 151 | None | 0.95A | 5cdpA-2pfxA:undetectable5cdpB-2pfxA:undetectable | 5cdpA-2pfxA:18.985cdpB-2pfxA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pvp | D-ALANINE-D-ALANINELIGASE (Helicobacterpylori) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 5 | SER A 173GLU A 203GLY A 100ASP A 99GLY A 103 | None | 1.21A | 5cdpA-2pvpA:undetectable5cdpB-2pvpA:2.0 | 5cdpA-2pvpA:22.915cdpB-2pvpA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qxl | HEAT SHOCK PROTEINHOMOLOG SSE1 (Saccharomycescerevisiae) |
PF00012(HSP70) | 4 | SER A 353GLY A 234ASP A 236GLY A 205 | NoneATP A1002 (-3.6A)NoneATP A1002 (-3.5A) | 0.96A | 5cdpA-2qxlA:undetectable5cdpB-2qxlA:undetectable | 5cdpA-2qxlA:23.605cdpB-2qxlA:15.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r87 | PURP PROTEIN PF1517 (Pyrococcusfuriosus) |
PF06849(DUF1246)PF06973(DUF1297) | 4 | GLU A 193GLY A 19ASP A 22GLY A 313 | None | 0.99A | 5cdpA-2r87A:undetectable5cdpB-2r87A:undetectable | 5cdpA-2r87A:20.915cdpB-2r87A:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r9z | GLUTATHIONE AMIDEREDUCTASE (Marichromatiumgracile) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | SER A 35GLY A 301ASP A 302GLY A 15 | FAD A 500 (-3.4A)FAD A 500 (-3.2A)FAD A 500 (-2.7A)FAD A 500 (-3.5A) | 0.78A | 5cdpA-2r9zA:undetectable5cdpB-2r9zA:undetectable | 5cdpA-2r9zA:22.695cdpB-2r9zA:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rgj | FLAVIN-CONTAININGMONOOXYGENASE (Pseudomonasaeruginosa) |
PF01494(FAD_binding_3) | 4 | SER A 37GLY A 309ASP A 310GLY A 15 | FAD A 403 ( 4.0A)FAD A 403 (-3.3A)FAD A 403 (-2.7A)FAD A 403 (-3.3A) | 0.98A | 5cdpA-2rgjA:undetectable5cdpB-2rgjA:undetectable | 5cdpA-2rgjA:21.865cdpB-2rgjA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2trc | PHOSDUCIN (Rattusnorvegicus) |
PF02114(Phosducin) | 4 | SER P 203GLY P 178ASP P 179ARG P 180 | None | 0.82A | 5cdpA-2trcP:undetectable5cdpB-2trcP:undetectable | 5cdpA-2trcP:16.815cdpB-2trcP:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vml | PHYCOCYANIN ALPHACHAIN (Gloeobacterviolaceus) |
PF00502(Phycobilisome) | 4 | SER A 11GLY A 103ASP A 106GLY A 101 | None | 0.94A | 5cdpA-2vmlA:undetectable5cdpB-2vmlA:undetectable | 5cdpA-2vmlA:16.565cdpB-2vmlA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w2k | D-MANDELATEDEHYDROGENASE (Rhodotorulagraminis) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | SER B 109GLY B 10ASP B 11GLY B 63 | None | 0.93A | 5cdpA-2w2kB:undetectable5cdpB-2w2kB:undetectable | 5cdpA-2w2kB:22.985cdpB-2w2kB:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xkk | TOPOISOMERASE IV (Acinetobacterbaumannii) |
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim) | 5 | SER A1084GLU A1088GLY A 396ASP A 397GLY A 419 | MG A1504 ( 3.8A) MG A1504 ( 4.7A)NoneNoneNone | 0.68A | 5cdpA-2xkkA:49.05cdpB-2xkkA:23.1 | 5cdpA-2xkkA:29.965cdpB-2xkkA:17.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bga | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N)PF16353(DUF4981) | 4 | GLU A 682GLY A 893ASP A 894GLY A 908 | None | 0.83A | 5cdpA-3bgaA:undetectable5cdpB-3bgaA:undetectable | 5cdpA-3bgaA:19.645cdpB-3bgaA:11.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c49 | POLY(ADP-RIBOSE)POLYMERASE 3 (Homo sapiens) |
PF00644(PARP)PF02877(PARP_reg) | 4 | GLU A 367GLY A 447ASP A 467GLY A 377 | None | 0.72A | 5cdpA-3c49A:3.95cdpB-3c49A:undetectable | 5cdpA-3c49A:19.805cdpB-3c49A:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3czm | L-LACTATEDEHYDROGENASE (Toxoplasmagondii) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | SER A 67GLY A 27ASP A 53GLY A 32 | NoneNAD A 401 ( 3.8A)NAD A 401 (-2.9A)None | 0.93A | 5cdpA-3czmA:undetectable5cdpB-3czmA:undetectable | 5cdpA-3czmA:20.205cdpB-3czmA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gnq | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE, TYPEI (Burkholderiapseudomallei) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | GLU A 30GLY A 8ASP A 36GLY A 13 | None | 0.99A | 5cdpA-3gnqA:2.55cdpB-3gnqA:undetectable | 5cdpA-3gnqA:21.045cdpB-3gnqA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h84 | ATPASE GET3 (Saccharomycescerevisiae) |
PF02374(ArsA_ATPase) | 4 | SER A 55GLY A 323ARG A 322GLY A 67 | None | 0.88A | 5cdpA-3h84A:undetectable5cdpB-3h84A:undetectable | 5cdpA-3h84A:23.085cdpB-3h84A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hf8 | TRYPTOPHAN5-HYDROXYLASE 1 (Homo sapiens) |
PF00351(Biopterin_H) | 4 | SER A 285GLU A 380GLY A 276GLY A 331 | None | 0.85A | 5cdpA-3hf8A:undetectable5cdpB-3hf8A:undetectable | 5cdpA-3hf8A:21.545cdpB-3hf8A:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ide | CAPSID PROTEIN VP2 (Infectiouspancreaticnecrosis virus) |
PF01766(Birna_VP2) | 4 | SER A 108GLY A 51ARG A 69GLY A 49 | None | 0.75A | 5cdpA-3ideA:undetectable5cdpB-3ideA:undetectable | 5cdpA-3ideA:23.925cdpB-3ideA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ldh | LACTATEDEHYDROGENASE (Squalusacanthias) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | SER A 88GLY A 33ASP A 36GLY A 28 | NoneNoneNoneNAD A 332 (-1.8A) | 0.75A | 5cdpA-3ldhA:undetectable5cdpB-3ldhA:undetectable | 5cdpA-3ldhA:20.365cdpB-3ldhA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3meb | ASPARTATEAMINOTRANSFERASE (Giardiaintestinalis) |
PF00155(Aminotran_1_2) | 4 | SER A 131GLU A 154GLY A 375GLY A 396 | None | 0.94A | 5cdpA-3mebA:undetectable5cdpB-3mebA:undetectable | 5cdpA-3mebA:22.875cdpB-3mebA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3muo | PROLYL ENDOPEPTIDASE (Aeromonascaviae) |
PF00326(Peptidase_S9)PF02897(Peptidase_S9_N) | 4 | GLU A 387GLY A 540ARG A 535GLY A 457 | NoneNoneZPR A 702 (-4.1A)None | 0.91A | 5cdpA-3muoA:undetectable5cdpB-3muoA:3.6 | 5cdpA-3muoA:21.135cdpB-3muoA:13.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nd0 | SLL0855 PROTEIN (Synechocystissp. PCC 6803) |
PF00654(Voltage_CLC) | 4 | SER A 342GLY A 307ASP A 306GLY A 142 | None | 0.92A | 5cdpA-3nd0A:undetectable5cdpB-3nd0A:undetectable | 5cdpA-3nd0A:22.955cdpB-3nd0A:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o0h | GLUTATHIONEREDUCTASE (Bartonellahenselae) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | GLU A 112GLY A 304ASP A 305GLY A 16 | NoneFAD A 500 (-3.3A)FAD A 500 (-2.7A)FAD A 500 (-3.5A) | 0.64A | 5cdpA-3o0hA:undetectable5cdpB-3o0hA:undetectable | 5cdpA-3o0hA:21.855cdpB-3o0hA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oec | CARVEOLDEHYDROGENASE(MYTHA.01326.C,A0R518 HOMOLOG) (Mycolicibacteriumthermoresistibile) |
PF13561(adh_short_C2) | 4 | GLU A 82GLY A 31ASP A 55GLY A 37 | None | 0.92A | 5cdpA-3oecA:undetectable5cdpB-3oecA:3.2 | 5cdpA-3oecA:23.165cdpB-3oecA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p06 | VP4 PROTEIN (Tellina virus) |
no annotation | 4 | SER A 671GLU A 672GLY A 688GLY A 710 | NoneGOL A 102 ( 4.8A)NoneNone | 0.94A | 5cdpA-3p06A:undetectable5cdpB-3p06A:undetectable | 5cdpA-3p06A:15.565cdpB-3p06A:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qc2 | GLYCOSYL HYDROLASE (Bacteroidesovatus) |
PF04041(Glyco_hydro_130) | 4 | SER A 72GLU A 55GLY A 102GLY A 100 | None | 0.70A | 5cdpA-3qc2A:undetectable5cdpB-3qc2A:undetectable | 5cdpA-3qc2A:23.125cdpB-3qc2A:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r4t | 4-AMINOBUTYRATEAMINOTRANSFERASEGABT (Mycobacteriummarinum) |
PF00202(Aminotran_3) | 4 | GLU A 234GLY A 272ARG A 374GLY A 375 | None | 0.97A | 5cdpA-3r4tA:undetectable5cdpB-3r4tA:undetectable | 5cdpA-3r4tA:21.515cdpB-3r4tA:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sc4 | SHORT CHAINDEHYDROGENASE(A0QTM2 HOMOLOG) (Mycolicibacteriumthermoresistibile) |
PF00106(adh_short) | 4 | GLU A 58GLY A 12ARG A 15GLY A 18 | NoneUNL A 290 ( 3.3A)UNL A 288 (-3.7A)EDO A 282 (-3.8A) | 0.99A | 5cdpA-3sc4A:undetectable5cdpB-3sc4A:2.5 | 5cdpA-3sc4A:21.185cdpB-3sc4A:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3slk | POLYKETIDE SYNTHASEEXTENDER MODULE 2 (Saccharopolysporaspinosa) |
PF08240(ADH_N)PF08659(KR)PF13602(ADH_zinc_N_2) | 4 | SER A 692GLU A 696GLY A 516GLY A 522 | NoneNoneNDP A 802 (-3.3A)None | 0.93A | 5cdpA-3slkA:undetectable5cdpB-3slkA:3.2 | 5cdpA-3slkA:21.185cdpB-3slkA:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t33 | G PROTEIN COUPLEDRECEPTOR (Arabidopsisthaliana) |
PF05147(LANC_like) | 4 | SER A 256GLY A 204ARG A 205GLY A 208 | None | 0.98A | 5cdpA-3t33A:undetectable5cdpB-3t33A:undetectable | 5cdpA-3t33A:23.175cdpB-3t33A:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u95 | GLYCOSIDE HYDROLASE,FAMILY 4 (Thermotoganeapolitana) |
PF02056(Glyco_hydro_4)PF11975(Glyco_hydro_4C) | 4 | GLU A 394GLY A 266ASP A 267GLY A 186 | NoneNone MN A 601 ( 4.6A)None | 0.93A | 5cdpA-3u95A:undetectable5cdpB-3u95A:undetectable | 5cdpA-3u95A:22.245cdpB-3u95A:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vvl | HOMOSERINEO-ACETYLTRANSFERASE (Streptomyceslavendulae) |
PF00561(Abhydrolase_1) | 4 | SER A 276GLY A 207ARG A 211GLY A 209 | None | 0.99A | 5cdpA-3vvlA:undetectable5cdpB-3vvlA:2.4 | 5cdpA-3vvlA:22.575cdpB-3vvlA:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w01 | HEPTAPRENYLGLYCERYLPHOSPHATE SYNTHASE (Staphylococcusaureus) |
PF01884(PcrB) | 4 | SER A 176GLU A 177GLY A 188GLY A 167 | None | 0.99A | 5cdpA-3w01A:undetectable5cdpB-3w01A:undetectable | 5cdpA-3w01A:18.975cdpB-3w01A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wx5 | CELLULASE (unculturedbacterium) |
PF01670(Glyco_hydro_12) | 4 | SER A 251GLY A 51ASP A 47ARG A 54 | None | 0.91A | 5cdpA-3wx5A:undetectable5cdpB-3wx5A:undetectable | 5cdpA-3wx5A:17.865cdpB-3wx5A:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5q | CHI1 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 4 | SER A 78GLY A 213ASP A 254GLY A 118 | None | 0.90A | 5cdpA-4a5qA:undetectable5cdpB-4a5qA:undetectable | 5cdpA-4a5qA:23.125cdpB-4a5qA:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cr6 | N-ACYLMANNOSAMINE1-DEHYDROGENASE (Flavobacteriumsp. 141-8) |
PF13561(adh_short_C2) | 4 | GLU A 231GLY A 264ASP A 219ARG A 270 | None | 0.74A | 5cdpA-4cr6A:undetectable5cdpB-4cr6A:3.5 | 5cdpA-4cr6A:21.995cdpB-4cr6A:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dok | SIMILARITY TOCHALCONE-FLAVONONEISOMERASE (Arabidopsisthaliana) |
PF02431(Chalcone) | 4 | SER A 81GLY A 191ARG A 190GLY A 188 | None | 0.74A | 5cdpA-4dokA:undetectable5cdpB-4dokA:undetectable | 5cdpA-4dokA:18.225cdpB-4dokA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dqk | BIFUNCTIONALP-450/NADPH-P450REDUCTASE (Bacillusmegaterium) |
PF00175(NAD_binding_1)PF00667(FAD_binding_1) | 4 | SER A 844GLU A 686GLY A 903GLY A 905 | NoneNoneNoneSO4 A1104 ( 4.2A) | 0.97A | 5cdpA-4dqkA:undetectable5cdpB-4dqkA:2.8 | 5cdpA-4dqkA:21.825cdpB-4dqkA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dzi | PUTATIVE TIM-BARRELMETAL-DEPENDENTHYDROLASE (Mycobacteriumavium) |
PF04909(Amidohydro_2) | 4 | SER A 169GLY A 49ARG A 33GLY A 34 | None | 0.93A | 5cdpA-4dziA:undetectable5cdpB-4dziA:undetectable | 5cdpA-4dziA:21.065cdpB-4dziA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f82 | THIOREDOXINREDUCTASE (Burkholderiacenocepacia) |
PF08534(Redoxin) | 4 | GLU A 15GLY A 140ASP A 139GLY A 39 | None | 0.87A | 5cdpA-4f82A:undetectable5cdpB-4f82A:undetectable | 5cdpA-4f82A:17.475cdpB-4f82A:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fff | LEVANFRUCTOTRANSFERASE (Paenarthrobacterureafaciens) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 4 | SER A 334GLY A 494ASP A 495ARG A 421 | None | 1.00A | 5cdpA-4fffA:undetectable5cdpB-4fffA:undetectable | 5cdpA-4fffA:22.785cdpB-4fffA:15.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gni | PUTATIVE HEAT SHOCKPROTEIN (Chaetomiumthermophilum) |
PF00012(HSP70) | 4 | SER A 26ASP A 218ARG A 216GLY A 214 | NoneNoneNoneATP A 502 (-3.6A) | 0.95A | 5cdpA-4gniA:undetectable5cdpB-4gniA:undetectable | 5cdpA-4gniA:24.405cdpB-4gniA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h09 | HYPOTHETICAL LEUCINERICH REPEAT PROTEIN (Eubacteriumventriosum) |
PF13306(LRR_5) | 4 | SER A 98GLY A 137ASP A 138GLY A 115 | NonePEG A 501 ( 4.0A)NonePEG A 501 (-3.6A) | 0.94A | 5cdpA-4h09A:undetectable5cdpB-4h09A:undetectable | 5cdpA-4h09A:23.825cdpB-4h09A:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4huh | TAIL CONNECTORPROTEIN GP15 (Escherichiavirus T4) |
PF16724(T4-gp15_tss) | 4 | SER A 9GLY A 154ASP A 156GLY A 207 | None | 0.74A | 5cdpA-4huhA:2.35cdpB-4huhA:undetectable | 5cdpA-4huhA:20.455cdpB-4huhA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j8b | COATOMER ALPHASUBUNIT (Schizosaccharomycespombe) |
PF00400(WD40) | 4 | GLY A 72ASP A 73ARG A 57GLY A 58 | None | 0.77A | 5cdpA-4j8bA:undetectable5cdpB-4j8bA:undetectable | 5cdpA-4j8bA:18.695cdpB-4j8bA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jso | OLIGOPEPTIDE ABCTRANSPORTER,PERIPLASMICOLIGOPEPTIDE-BINDINGPROTEIN (Thermotogamaritima) |
PF00496(SBP_bac_5) | 4 | GLU A 388GLY A 359ASP A 358GLY A 398 | None | 0.74A | 5cdpA-4jsoA:3.05cdpB-4jsoA:undetectable | 5cdpA-4jsoA:22.675cdpB-4jsoA:14.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ksi | LEUCINEAMINOPEPTIDASE 1,CHLOROPLASTIC (Solanumlycopersicum) |
PF00883(Peptidase_M17)PF02789(Peptidase_M17_N) | 4 | SER A 348GLY A 410ASP A 411ARG A 408 | None | 0.74A | 5cdpA-4ksiA:undetectable5cdpB-4ksiA:1.7 | 5cdpA-4ksiA:23.005cdpB-4ksiA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n74 | PREDICTED OUTERMEMBRANE PROTEIN ANDSURFACE ANTIGEN (Escherichiacoli) |
PF01103(Bac_surface_Ag) | 4 | SER A 546GLY A 541ASP A 554GLY A 516 | None | 0.99A | 5cdpA-4n74A:undetectable5cdpB-4n74A:undetectable | 5cdpA-4n74A:23.015cdpB-4n74A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nv0 | 7-METHYLGUANOSINEPHOSPHATE-SPECIFIC5'-NUCLEOTIDASE (Drosophilamelanogaster) |
PF05822(UMPH-1) | 4 | SER A 254GLU A 221GLY A 266GLY A 244 | None | 0.96A | 5cdpA-4nv0A:undetectable5cdpB-4nv0A:undetectable | 5cdpA-4nv0A:20.505cdpB-4nv0A:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o4f | INOSITOLHEXAKISPHOSPHATEKINASE (Entamoebahistolytica) |
PF03770(IPK) | 4 | SER A 136GLY A 248ASP A 247GLY A 252 | IHP A 403 ( 4.3A)PO4 A 406 (-3.7A)PO4 A 406 (-2.9A)None | 0.77A | 5cdpA-4o4fA:1.85cdpB-4o4fA:undetectable | 5cdpA-4o4fA:20.205cdpB-4o4fA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pbc | D-AMINO ACIDAMINOTRANSFERASE (Burkholderiacenocepacia) |
PF01063(Aminotran_4) | 4 | GLU A 188GLY A 42ASP A 40GLY A 48 | None | 0.93A | 5cdpA-4pbcA:undetectable5cdpB-4pbcA:undetectable | 5cdpA-4pbcA:23.085cdpB-4pbcA:19.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4plb | CHIMERA PROTEIN OFDNA GYRASE SUBUNITSB AND A (Staphylococcusaureus) |
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim) | 4 | SER B1084GLU B1088ARG B 458GLY B 459 | None | 0.78A | 5cdpA-4plbB:58.55cdpB-4plbB:31.5 | 5cdpA-4plbB:100.005cdpB-4plbB:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4plb | CHIMERA PROTEIN OFDNA GYRASE SUBUNITSB AND A (Staphylococcusaureus) |
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim) | 4 | SER B1084GLU B1088GLY B 436GLY B 459 | None | 0.70A | 5cdpA-4plbB:58.55cdpB-4plbB:31.5 | 5cdpA-4plbB:100.005cdpB-4plbB:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rmx | PHI92_GP150 (Enterobacteriaphage phi92) |
no annotation | 4 | GLY A 658ASP A 657ARG A 662GLY A 660 | None | 0.87A | 5cdpA-4rmxA:undetectable5cdpB-4rmxA:undetectable | 5cdpA-4rmxA:19.945cdpB-4rmxA:13.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uar | PROTEIN CBBY (Rhodobactersphaeroides) |
PF13419(HAD_2) | 4 | SER A 177GLU A 202ASP A 155GLY A 186 | None | 0.96A | 5cdpA-4uarA:undetectable5cdpB-4uarA:2.2 | 5cdpA-4uarA:21.175cdpB-4uarA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x0e | PROBABLENICOTINATE-NUCLEOTIDEADENYLYLTRANSFERASE (Mycobacteriumtuberculosis) |
PF01467(CTP_transf_like) | 4 | GLY A 42ASP A 77ARG A 80GLY A 82 | None | 0.95A | 5cdpA-4x0eA:undetectable5cdpB-4x0eA:3.2 | 5cdpA-4x0eA:18.185cdpB-4x0eA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zg7 | ECTONUCLEOTIDEPYROPHOSPHATASE/PHOSPHODIESTERASE FAMILYMEMBER 2 (Homo sapiens) |
PF01033(Somatomedin_B)PF01223(Endonuclease_NS)PF01663(Phosphodiest) | 4 | GLU A 860GLY A 315ASP A 312GLY A 473 | NoneNone ZN A 903 ( 2.0A)None | 0.75A | 5cdpA-4zg7A:3.55cdpB-4zg7A:undetectable | 5cdpA-4zg7A:21.145cdpB-4zg7A:13.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5boe | ENOLASE (Staphylococcusaureus) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | GLU A 249ASP A 402ARG A 400GLY A 396 | None | 0.97A | 5cdpA-5boeA:undetectable5cdpB-5boeA:undetectable | 5cdpA-5boeA:22.335cdpB-5boeA:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cdo | DNA GYRASE SUBUNITB,DNA GYRASE SUBUNITB (Staphylococcusaureus) |
PF00986(DNA_gyraseB_C)PF01751(Toprim) | 4 | GLY B 436ASP B 437ARG B 458GLY B 459 | None | 0.68A | 5cdpA-5cdoB:undetectable5cdpB-5cdoB:33.1 | 5cdpA-5cdoB:17.995cdpB-5cdoB:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5chc | DMSO REDUCTASEFAMILY TYPE IIENZYME,MOLYBDOPTERINSUBUNIT (Azospira oryzae) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 4 | SER A 765GLY A 80ASP A 82GLY A 77 | NoneNone NA A1015 ( 4.9A)SF4 A1001 ( 3.7A) | 0.87A | 5cdpA-5chcA:undetectable5cdpB-5chcA:undetectable | 5cdpA-5chcA:19.185cdpB-5chcA:11.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dl5 | MEMBRANE PROTEIN (Acinetobacterbaumannii) |
PF03573(OprD) | 4 | SER A 37GLY A 65ASP A 64ARG A 94 | NoneC8E A 502 (-3.9A)NoneNone | 0.91A | 5cdpA-5dl5A:undetectable5cdpB-5dl5A:undetectable | 5cdpA-5dl5A:21.765cdpB-5dl5A:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e02 | FRQ-INTERACTING RNAHELICASE (Neurosporacrassa) |
PF00270(DEAD)PF00271(Helicase_C)PF08148(DSHCT)PF13234(rRNA_proc-arch) | 4 | SER A 124GLY A 579ARG A 548GLY A 587 | None | 0.53A | 5cdpA-5e02A:undetectable5cdpB-5e02A:undetectable | 5cdpA-5e02A:19.015cdpB-5e02A:10.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f12 | NAD(P)HDEHYDROGENASE(QUINONE) (Escherichiacoli) |
PF03358(FMN_red) | 4 | GLU A 40GLY A 167ASP A 168GLY A 114 | MHO A 10 ( 4.7A)NoneNoneFMN A 201 (-3.6A) | 0.95A | 5cdpA-5f12A:undetectable5cdpB-5f12A:3.6 | 5cdpA-5f12A:16.155cdpB-5f12A:24.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fq6 | SUSC/RAGA FAMILYTONB-LINKED OUTERMEMBRANE PROTEIN (Bacteroidesthetaiotaomicron) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | SER B 831GLU B 966GLY B 891GLY B 888 | None | 0.94A | 5cdpA-5fq6B:undetectable5cdpB-5fq6B:undetectable | 5cdpA-5fq6B:20.175cdpB-5fq6B:10.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j72 | PUTATIVEN-ACETYLMURAMOYL-L-ALANINEAMIDASE,AUTOLYSINCWP6 (Clostridioidesdifficile) |
PF01520(Amidase_3)PF04122(CW_binding_2) | 4 | SER A 373GLU A 422ASP A 190GLY A 160 | NoneNone CA A 701 (-3.4A)None | 0.91A | 5cdpA-5j72A:undetectable5cdpB-5j72A:3.5 | 5cdpA-5j72A:22.785cdpB-5j72A:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l01 | TRYPTOPHAN5-HYDROXYLASE 1 (Homo sapiens) |
PF00351(Biopterin_H) | 4 | SER A 285GLU A 380GLY A 276GLY A 331 | None | 0.83A | 5cdpA-5l01A:undetectable5cdpB-5l01A:undetectable | 5cdpA-5l01A:20.675cdpB-5l01A:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lp7 | ACETYL-COAACETYLTRANSFERASE (Bacillussubtilis) |
no annotation | 4 | GLU H 192GLY H 372ASP H 312GLY H 370 | None | 0.87A | 5cdpA-5lp7H:undetectable5cdpB-5lp7H:undetectable | 5cdpA-5lp7H:22.225cdpB-5lp7H:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n1t | CYTOCHROME CFLAVIN-BINDINGSUBUNIT OF SULFIDEDEHYDROGENASE (Thioalkalivibrioparadoxus) |
no annotation | 4 | SER B 29GLY A 414ASP A 417GLY B 24 | None | 0.79A | 5cdpA-5n1tB:undetectable5cdpB-5n1tB:undetectable | 5cdpA-5n1tB:9.945cdpB-5n1tB:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vrf | CADMIUM AND ZINCEFFLUX PUMP FIEF (Shewanellaoneidensis) |
no annotation | 4 | GLY B 182ASP B 181ARG B 106GLY B 104 | None | 0.97A | 5cdpA-5vrfB:undetectable5cdpB-5vrfB:undetectable | 5cdpA-5vrfB:9.915cdpB-5vrfB:16.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wvb | CHITINASE (Ostriniafurnacalis) |
no annotation | 4 | SER A 103GLY A 174ASP A 215GLY A 130 | NoneNoneNAG A 504 (-3.8A)None | 0.85A | 5cdpA-5wvbA:undetectable5cdpB-5wvbA:undetectable | 5cdpA-5wvbA:13.375cdpB-5wvbA:15.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x9w | DNA MISMATCH REPAIRPROTEIN MUTS (Neisseriagonorrhoeae) |
no annotation | 4 | SER A 145GLU A 150GLY A 83GLY A 189 | None | 0.85A | 5cdpA-5x9wA:undetectable5cdpB-5x9wA:undetectable | 5cdpA-5x9wA:21.335cdpB-5x9wA:12.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xvs | GDP/UDP-N,N'-DIACETYLBACILLOSAMINE2-EPIMERASE(HYDROLYZING) (Acinetobacterbaumannii) |
no annotation | 4 | SER A 290GLY A 354ASP A 179GLY A 352 | UDP A 402 (-2.4A)NoneNoneNone | 0.97A | 5cdpA-5xvsA:undetectable5cdpB-5xvsA:2.8 | 5cdpA-5xvsA:9.595cdpB-5xvsA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yh1 | - (-) |
no annotation | 4 | GLU A 549GLY A 367ASP A 364GLY A 499 | NoneNone MN A 805 ( 4.7A)None | 0.97A | 5cdpA-5yh1A:3.45cdpB-5yh1A:3.0 | 5cdpA-5yh1A:undetectable5cdpB-5yh1A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yhh | UNCHARACTERIZEDCONSERVED PROTEINYIIM (Geobacillusstearothermophilus) |
no annotation | 4 | GLU A 181GLY A 165ASP A 101GLY A 167 | None | 0.98A | 5cdpA-5yhhA:undetectable5cdpB-5yhhA:undetectable | 5cdpA-5yhhA:11.145cdpB-5yhhA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ykb | TREHALOSE SYNTHASE (Deinococcusradiodurans) |
no annotation | 4 | GLU A 386GLY A 100ASP A 101ARG A 207 | None | 0.90A | 5cdpA-5ykbA:undetectable5cdpB-5ykbA:undetectable | 5cdpA-5ykbA:20.885cdpB-5ykbA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c7s | PUTATIVE RIFAMPINMONOOXYGENASE (Nocardiafarcinica) |
no annotation | 4 | SER A 318GLU A 322GLY A 308ARG A 427 | None | 0.79A | 5cdpA-6c7sA:2.85cdpB-6c7sA:undetectable | 5cdpA-6c7sA:13.355cdpB-6c7sA:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fos | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A1PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A2 (Cyanidioschyzonmerolae) |
no annotation | 4 | SER A 716GLY A 573ASP A 572GLY B 559 | NoneSF4 A3001 ( 4.0A)NoneNone | 0.72A | 5cdpA-6fosA:undetectable5cdpB-6fosA:undetectable | 5cdpA-6fosA:9.845cdpB-6fosA:16.93 |