SIMILAR PATTERNS OF AMINO ACIDS FOR 5C6P_A_4YHA601

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c7t BETA-N-ACETYLHEXOSAM
INIDASE

(Serratia
marcescens) 		PF00728
(Glyco_hydro_20)
PF02838
(Glyco_hydro_20b)
PF03173
(CHB_HEX)
PF03174
(CHB_HEX_C) 		4 ALA A 157
SER A 154
GLN A  34
SER A  36
 None
 1.19A 5c6pA-1c7tA:
0.0		 5c6pA-1c7tA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6y METHYL-COENZYME M
REDUCTASE I BETA
SUBUNIT
METHYL-COENZYME M
REDUCTASE SUBUNIT
GAMMA

(Methanosarcina
barkeri) 		PF02240
(MCR_gamma)
PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		4 ALA B2210
SER B2209
SER C3066
ASP B2009
 None
None
OCS  C3065 ( 4.1A)
None
 1.09A 5c6pA-1e6yB:
0.0		 5c6pA-1e6yB:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fbw ENDO-1,4-BETA-GLUCAN
ASE F

([Clostridium]
cellulolyticum) 		PF02011
(Glyco_hydro_48) 		4 ALA A 404
GLN A 553
ASP A 117
PRO A 118
 None
 1.03A 5c6pA-1fbwA:
0.0		 5c6pA-1fbwA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fvf SEC1

(Doryteuthis
pealeii) 		PF00995
(Sec1) 		4 ALA A 248
SER A 550
GLN A 368
SER A 478
 None
 1.22A 5c6pA-1fvfA:
0.0		 5c6pA-1fvfA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gkr NON-ATP DEPENDENT
L-SELECTIVE
HYDANTOINASE

(Paenarthrobacter
aurescens) 		PF01979
(Amidohydro_1) 		4 ALA A 369
GLN A 382
SER A 385
PRO A  54
 None
 1.11A 5c6pA-1gkrA:
0.0		 5c6pA-1gkrA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gq2 MALIC ENZYME

(Columba livia) 		PF00390
(malic)
PF03949
(Malic_M) 		4 ALA A 289
SER A 285
SER A 468
PRO A 514
 None
 1.09A 5c6pA-1gq2A:
0.0		 5c6pA-1gq2A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kwc 2,3-DIHYDROXYBIPHENY
L DIOXYGENASE

(Pseudomonas sp.
KKS102) 		PF00903
(Glyoxalase) 		4 ALA B 145
SER B 247
ASP B 243
PRO B 265
 None
None
BPY  B 401 (-3.9A)
None
 1.14A 5c6pA-1kwcB:
undetectable		 5c6pA-1kwcB:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nhy ELONGATION FACTOR
1-GAMMA 1

(Saccharomyces
cerevisiae) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 ALA A 103
SER A 101
GLN A  95
ASP A 162
 None
 1.18A 5c6pA-1nhyA:
0.0		 5c6pA-1nhyA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pjb L-ALANINE
DEHYDROGENASE

(Phormidium
lapideum) 		PF01262
(AlaDh_PNT_C)
PF05222
(AlaDh_PNT_N) 		4 ALA A 136
SER A 133
GLN A 270
ASP A 265
 None
 0.89A 5c6pA-1pjbA:
0.0		 5c6pA-1pjbA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qb4 PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Escherichia
coli) 		PF00311
(PEPcase) 		4 ALA A 714
SER A 542
GLN A 613
PRO A 139
 None
 0.96A 5c6pA-1qb4A:
undetectable		 5c6pA-1qb4A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qnl ALIPHATIC AMIDASE
EXPRESSION-REGULATIN
G PROTEIN

(Pseudomonas
aeruginosa) 		PF13433
(Peripla_BP_5) 		4 ALA A 264
SER A 265
GLN A 356
SER A 339
 None
 1.00A 5c6pA-1qnlA:
undetectable		 5c6pA-1qnlA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vbg PYRUVATE,ORTHOPHOSPH
ATE DIKINASE

(Zea mays) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N)
PF02896
(PEP-utilizers_C) 		4 ALA A 571
SER A 572
ASP A 547
PRO A 546
 None
 1.01A 5c6pA-1vbgA:
undetectable		 5c6pA-1vbgA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w85 PYRUVATE
DEHYDROGENASE E1
COMPONENT, ALPHA
SUBUNIT

(Geobacillus
stearothermophilus) 		PF00676
(E1_dh) 		4 ALA A  87
SER A  88
GLN A  81
PRO A 295
 None
 0.79A 5c6pA-1w85A:
undetectable		 5c6pA-1w85A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ag1 BENZALDEHYDE LYASE

(Pseudomonas
fluorescens) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 ALA A 215
SER A 216
ASP A 302
PRO A 303
 None
 1.12A 5c6pA-2ag1A:
undetectable		 5c6pA-2ag1A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bjq MFP2A

(Ascaris suum) 		PF12150
(MFP2b) 		4 ALA A  48
GLN A 260
SER A 258
PRO A  23
 None
 1.03A 5c6pA-2bjqA:
undetectable		 5c6pA-2bjqA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bjr MFP2B

(Ascaris suum) 		PF12150
(MFP2b) 		4 ALA A  49
GLN A 270
SER A 268
PRO A  24
 None
 0.88A 5c6pA-2bjrA:
undetectable		 5c6pA-2bjrA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bod ENDOGLUCANASE E-2

(Thermobifida
fusca) 		PF01341
(Glyco_hydro_6) 		4 ALA X 151
SER X 149
GLN X  62
PRO X  68
 None
 1.20A 5c6pA-2bodX:
undetectable		 5c6pA-2bodX:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bod ENDOGLUCANASE E-2

(Thermobifida
fusca) 		PF01341
(Glyco_hydro_6) 		4 ALA X 283
GLN X  38
SER X  35
PRO X 242
 None
 1.16A 5c6pA-2bodX:
undetectable		 5c6pA-2bodX:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c3o PYRUVATE-FERREDOXIN
OXIDOREDUCTASE

(Desulfovibrio
africanus) 		PF01558
(POR)
PF01855
(POR_N)
PF02775
(TPP_enzyme_C)
PF10371
(EKR)
PF13484
(Fer4_16)
PF17147
(PFOR_II) 		4 ALA A1038
SER A1058
ASP A1102
PRO A1103
 None
 1.07A 5c6pA-2c3oA:
undetectable		 5c6pA-2c3oA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cev PROTEIN (ARGINASE)

([Bacillus]
caldovelox) 		PF00491
(Arginase) 		4 ALA A 123
SER A 176
ASP A 231
PRO A 232
 MN  A 302 ( 4.5A)
None
None
None
 0.79A 5c6pA-2cevA:
undetectable		 5c6pA-2cevA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e8e HYPOTHETICAL PROTEIN
AQ_1549

(Aquifex
aeolicus) 		PF02566
(OsmC) 		4 ALA A  14
SER A  12
SER A  18
PRO A  34
 None
 1.22A 5c6pA-2e8eA:
undetectable		 5c6pA-2e8eA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ef4 ARGINASE

(Thermus
thermophilus) 		PF00491
(Arginase) 		4 ALA A 120
SER A 170
ASP A 223
PRO A 224
 None
 0.83A 5c6pA-2ef4A:
undetectable		 5c6pA-2ef4A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fv0 UNSATURATED
GLUCURONYL HYDROLASE

(Bacillus sp.
GL1) 		PF07470
(Glyco_hydro_88) 		4 ALA A 281
SER A 280
GLN A 211
ASP A 266
 None
None
GAD  A 404 ( 3.2A)
None
 1.22A 5c6pA-2fv0A:
undetectable		 5c6pA-2fv0A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gs5 CONSERVED
HYPOTHETICAL PROTEIN

(Corynebacterium
diphtheriae) 		PF02622
(DUF179) 		4 ALA A 167
SER A 163
ASP A 172
PRO A 192
 None
 1.17A 5c6pA-2gs5A:
undetectable		 5c6pA-2gs5A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hdw HYPOTHETICAL PROTEIN
PA2218

(Pseudomonas
aeruginosa) 		PF02129
(Peptidase_S15) 		4 ALA A 158
SER A 113
ASP A 131
PRO A 132
 None
 1.12A 5c6pA-2hdwA:
undetectable		 5c6pA-2hdwA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hih LIPASE 46 KDA FORM

(Staphylococcus
hyicus) 		no annotation 4 ALA A 182
SER A 183
SER A 124
ASP A 314
 None
 1.07A 5c6pA-2hihA:
undetectable		 5c6pA-2hihA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i6u ORNITHINE
CARBAMOYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 ALA A 193
SER A 189
GLN A 105
ASP A   8
 None
 1.22A 5c6pA-2i6uA:
undetectable		 5c6pA-2i6uA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipa PROTEIN ARSC

(Bacillus
subtilis) 		PF01451
(LMWPc) 		4 ALA B  37
SER B  36
SER B  82
PRO B  90
 None
 1.15A 5c6pA-2ipaB:
undetectable		 5c6pA-2ipaB:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kxq E3 UBIQUITIN-PROTEIN
LIGASE SMURF2

(Homo sapiens) 		PF00397
(WW) 		4 ALA A 332
SER A 331
GLN A 324
PRO A 300
 None
 1.09A 5c6pA-2kxqA:
undetectable		 5c6pA-2kxqA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l41 RRM DOMAIN FROM
NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3

(Saccharomyces
cerevisiae) 		PF00076
(RRM_1) 		4 GLN A  48
SER A  49
ASP A  45
PRO A   1
 None
 1.09A 5c6pA-2l41A:
undetectable		 5c6pA-2l41A:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5t PEZT
PUTATIVE
TRANSCRIPTIONAL
REGULATOR PEZA

(Streptococcus
pneumoniae) 		PF06414
(Zeta_toxin)
no annotation 		4 GLN B 234
SER B 233
ASP B 206
PRO A  69
 None
 1.19A 5c6pA-2p5tB:
undetectable		 5c6pA-2p5tB:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q3q UNCHARACTERIZED
PROTEIN AT1G24000

(Arabidopsis
thaliana) 		PF00407
(Bet_v_1) 		4 ALA A  23
SER A  22
SER A  81
ASP A 114
 None
 1.00A 5c6pA-2q3qA:
undetectable		 5c6pA-2q3qA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9q 2'-DEOXYCYTIDINE
5'-TRIPHOSPHATE
DEAMINASE

(Agrobacterium
fabrum) 		PF06559
(DCD) 		4 ALA A 109
GLN A 166
SER A 165
ASP A 135
 None
 1.17A 5c6pA-2r9qA:
undetectable		 5c6pA-2r9qA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uv8 FATTY ACID SYNTHASE
SUBUNIT BETA (FAS1)

(Saccharomyces
cerevisiae) 		PF00698
(Acyl_transf_1)
PF01575
(MaoC_dehydratas)
PF08354
(DUF1729)
PF13452
(MaoC_dehydrat_N)
PF16073
(SAT) 		4 ALA G 509
SER G 510
ASP G 538
PRO G 537
 None
 1.05A 5c6pA-2uv8G:
undetectable		 5c6pA-2uv8G:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zj4 GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING] 1

(Homo sapiens) 		PF01380
(SIS) 		4 ALA A 660
GLN A 325
SER A 321
ASP A 668
 None
 1.02A 5c6pA-2zj4A:
undetectable		 5c6pA-2zj4A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aay PUTATIVE THIOSULFATE
SULFURTRANSFERASE

(Mycobacterium
tuberculosis) 		PF00581
(Rhodanese) 		4 ALA A  92
SER A 240
GLN A  52
ASP A  28
 None
None
GOL  A 701 (-3.6A)
None
 1.18A 5c6pA-3aayA:
undetectable		 5c6pA-3aayA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cg1 UPF0100 PROTEIN
PF0080

(Pyrococcus
furiosus) 		PF13531
(SBP_bac_11) 		4 ALA A  78
SER A  42
ASP A 160
PRO A 161
 None
WO4  A 701 (-3.0A)
WO4  A 701 (-2.7A)
WO4  A 701 (-3.7A)
 1.16A 5c6pA-3cg1A:
undetectable		 5c6pA-3cg1A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cg3 UPF0100 PROTEIN
PH0151

(Pyrococcus
horikoshii) 		PF13531
(SBP_bac_11) 		4 ALA A  73
SER A  37
ASP A 155
PRO A 156
 None
WO4  A 701 (-2.4A)
WO4  A 701 (-2.8A)
WO4  A 701 (-3.7A)
 1.16A 5c6pA-3cg3A:
undetectable		 5c6pA-3cg3A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cvg PUTATIVE METAL
BINDING PROTEIN

(Coccidioides
immitis) 		PF12849
(PBP_like_2) 		4 ALA A 173
SER A 172
GLN A  49
ASP A 123
 CA  A 401 ( 3.8A)
CA  A 401 ( 3.8A)
None
None
 1.22A 5c6pA-3cvgA:
undetectable		 5c6pA-3cvgA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eev CHLORAMPHENICOL
ACETYLTRANSFERASE

(Vibrio cholerae) 		PF00132
(Hexapep) 		4 ALA A 207
SER A 205
SER A 187
PRO A 180
 None
 0.96A 5c6pA-3eevA:
undetectable		 5c6pA-3eevA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fo5 THIOESTERASE,
ADIPOSE ASSOCIATED,
ISOFORM BFIT2

(Homo sapiens) 		PF01852
(START) 		4 ALA A 550
SER A 425
SER A 394
PRO A 374
 GOL  A 595 (-4.3A)
None
None
None
 1.14A 5c6pA-3fo5A:
undetectable		 5c6pA-3fo5A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ln3 DIHYDRODIOL
DEHYDROGENASE

(Mus musculus) 		PF00248
(Aldo_ket_red) 		4 ALA A  37
SER A  34
SER A  67
ASP A  43
 MLY  A  33 ( 3.4A)
MLY  A  31 ( 4.0A)
MLY  A  68 ( 3.1A)
MLY  A  68 ( 2.8A)
 1.20A 5c6pA-3ln3A:
undetectable		 5c6pA-3ln3A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n23 SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1

(Sus scrofa) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF13246
(Cation_ATPase) 		4 ALA A 448
SER A 447
SER A 215
PRO A 587
 None
 1.04A 5c6pA-3n23A:
0.0		 5c6pA-3n23A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ohn OUTER MEMBRANE USHER
PROTEIN FIMD

(Escherichia
coli) 		PF00577
(Usher) 		4 ALA A 611
SER A 620
SER A 640
PRO A 282
 None
 0.72A 5c6pA-3ohnA:
undetectable		 5c6pA-3ohnA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ouk PROBABLE CONSERVED
TRANSMEMBRANE
PROTEIN

(Mycobacterium
tuberculosis) 		no annotation 4 ALA A 186
SER A 187
SER A 205
PRO A 199
 None
 1.21A 5c6pA-3oukA:
undetectable		 5c6pA-3oukA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p1u SUSD HOMOLOG

(Parabacteroides
distasonis) 		PF12741
(SusD-like) 		4 ALA A 436
SER A 410
ASP A 318
PRO A 319
 None
 1.07A 5c6pA-3p1uA:
undetectable		 5c6pA-3p1uA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pbk FATTY ACYL-ADENYLATE
LIGASE

(Escherichia
coli) 		PF00501
(AMP-binding) 		4 ALA A 118
SER A 115
SER A 548
PRO A 191
 None
 1.22A 5c6pA-3pbkA:
undetectable		 5c6pA-3pbkA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pzl AGMATINE
UREOHYDROLASE

(Thermoplasma
volcanium) 		PF00491
(Arginase) 		4 ALA A 145
SER A 183
ASP A 234
PRO A 235
 MN  A 315 ( 4.9A)
None
None
None
 0.75A 5c6pA-3pzlA:
undetectable		 5c6pA-3pzlA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qh4 ESTERASE LIPW

(Mycobacterium
marinum) 		PF07859
(Abhydrolase_3) 		4 ALA A 209
SER A 162
ASP A 254
PRO A 255
 None
 0.87A 5c6pA-3qh4A:
undetectable		 5c6pA-3qh4A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tpa HEME-BINDING PROTEIN
A

(Glaesserella
parasuis) 		PF00496
(SBP_bac_5) 		4 SER A 428
GLN A 454
ASP A 418
PRO A 152
 None
 0.91A 5c6pA-3tpaA:
undetectable		 5c6pA-3tpaA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wiw GLYCOSYL HYDROLASE
FAMILY 88

(Pedobacter
heparinus) 		PF07470
(Glyco_hydro_88) 		4 ALA A 308
SER A 307
GLN A 236
ASP A 293
 None
None
EPE  A 501 ( 4.3A)
None
 1.20A 5c6pA-3wiwA:
undetectable		 5c6pA-3wiwA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zbv ANGIOGENIN-2

(Mus musculus) 		PF00074
(RnaseA) 		4 ALA A  95
SER A  96
GLN A  76
PRO A  18
 None
 1.08A 5c6pA-3zbvA:
undetectable		 5c6pA-3zbvA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zpx LIPASE

(Ustilago maydis) 		PF03583
(LIP) 		4 ALA A 236
SER A 239
GLN A  98
SER A 269
 None
 1.12A 5c6pA-3zpxA:
undetectable		 5c6pA-3zpxA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0h ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE

(Arabidopsis
thaliana) 		PF00202
(Aminotran_3)
PF13500
(AAA_26) 		4 ALA A 485
SER A 487
ASP A 506
PRO A 507
 None
 1.12A 5c6pA-4a0hA:
undetectable		 5c6pA-4a0hA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c1t SUGAR TRANSPORTER
SOLUTE-BINDING
PROTEIN

(Bifidobacterium
animalis) 		PF01547
(SBP_bac_1) 		4 ALA A 261
SER A 260
GLN A  71
ASP A 284
 None
 1.14A 5c6pA-4c1tA:
undetectable		 5c6pA-4c1tA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cca SYNTAXIN-BINDING
PROTEIN 2

(Homo sapiens) 		PF00995
(Sec1) 		4 ALA A 251
SER A 545
GLN A 369
SER A 473
 None
 1.16A 5c6pA-4ccaA:
undetectable		 5c6pA-4ccaA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4egj D-ALANINE--D-ALANINE
LIGASE

(Paraburkholderia
xenovorans) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ALA A  13
SER A  26
ASP A  48
PRO A  49
 None
 1.20A 5c6pA-4egjA:
undetectable		 5c6pA-4egjA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eyo EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Rhodopseudomonas
palustris) 		PF13458
(Peripla_BP_6) 		4 ALA A 225
SER A 222
SER A 167
ASP A 199
 None
HC4  A 401 (-2.4A)
None
None
 0.98A 5c6pA-4eyoA:
undetectable		 5c6pA-4eyoA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f4f THREONINE SYNTHASE

(Brucella
melitensis) 		PF00291
(PALP)
PF14821
(Thr_synth_N) 		4 SER A 170
SER A 307
ASP A 384
PRO A 385
 None
PLP  A 501 (-3.3A)
None
None
 0.81A 5c6pA-4f4fA:
undetectable		 5c6pA-4f4fA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f53 SUSD HOMOLOG

(Bacteroides
ovatus) 		PF12741
(SusD-like) 		4 ALA A 285
SER A 338
ASP A 414
PRO A 415
 None
 1.00A 5c6pA-4f53A:
undetectable		 5c6pA-4f53A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ga4 PUTATIVE THYMIDINE
PHOSPHORYLASE

(Thermococcus
kodakarensis) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C) 		4 ALA A 249
SER A 264
ASP A 256
PRO A 257
 None
 0.97A 5c6pA-4ga4A:
undetectable		 5c6pA-4ga4A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ga6 PUTATIVE THYMIDINE
PHOSPHORYLASE

(Thermococcus
kodakarensis) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C) 		4 ALA A 249
SER A 264
ASP A 256
PRO A 257
 None
AMP  A 601 (-2.5A)
AMP  A 601 (-3.2A)
None
 1.07A 5c6pA-4ga6A:
undetectable		 5c6pA-4ga6A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ilf THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC

(Salmonella
enterica) 		PF10411
(DsbC_N)
PF13098
(Thioredoxin_2) 		4 SER A 138
GLN A 131
SER A 130
ASP A  95
 None
 1.19A 5c6pA-4ilfA:
undetectable		 5c6pA-4ilfA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l9f TRANSCRIPTIONAL
REGULATOR, PPSR

(Rhodobacter
sphaeroides) 		PF00989
(PAS) 		4 ALA A 179
SER A 177
ASP A 254
PRO A 255
 None
 1.16A 5c6pA-4l9fA:
undetectable		 5c6pA-4l9fA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgn CELLULOSE-BINDING,
FAMILY II

(Acidothermus
cellulolyticus) 		no annotation 4 ALA A 195
SER A 200
ASP A 135
PRO A 136
 None
 0.92A 5c6pA-4lgnA:
undetectable		 5c6pA-4lgnA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m8g TUMOR SUPPRESSOR
CANDIDATE 3

(Homo sapiens) 		PF04756
(OST3_OST6) 		4 SER A  88
SER A  44
ASP A 123
PRO A 119
 None
 1.08A 5c6pA-4m8gA:
undetectable		 5c6pA-4m8gA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mn8 FLG22
LRR RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE FLS2

(;
Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF00669
(Flagellin_N)
PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 ALA A 200
GLN C  65
SER C  75
ASP A 220
 None
 1.10A 5c6pA-4mn8A:
undetectable		 5c6pA-4mn8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nap EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 7

(Desulfovibrio
alaskensis) 		PF03480
(DctP) 		4 ALA A 120
SER A 124
GLN A  50
ASP A 214
 None
None
None
DTR  A 401 (-3.3A)
 1.22A 5c6pA-4napA:
undetectable		 5c6pA-4napA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ogc HNH ENDONUCLEASE
DOMAIN PROTEIN

(Actinomyces
naeslundii) 		PF01844
(HNH) 		4 ALA A 255
SER A 254
ASP A 396
PRO A 397
 None
 1.08A 5c6pA-4ogcA:
undetectable		 5c6pA-4ogcA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgq GLYCEROL-1-PHOSPHATE
DEHYDROGENASE

(Methanocaldococcus
jannaschii) 		PF13685
(Fe-ADH_2) 		4 ALA A 221
SER A 222
SER A 113
PRO A 110
 K  A 402 ( 3.6A)
13P  A 404 (-2.6A)
NDP  A 401 (-2.6A)
EDO  A 405 (-4.0A)
 1.11A 5c6pA-4rgqA:
undetectable		 5c6pA-4rgqA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkm MCCA

(Wolinella
succinogenes) 		no annotation 4 SER A 294
GLN A 241
SER A 284
PRO A 190
 None
 1.15A 5c6pA-4rkmA:
undetectable		 5c6pA-4rkmA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tkt AT-LESS POLYKETIDE
SYNTHASE

(Streptomyces
platensis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 ALA A3500
SER A3498
SER A3350
PRO A3153
 None
 1.18A 5c6pA-4tktA:
undetectable		 5c6pA-4tktA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4twe N-ACETYLATED-ALPHA-L
INKED ACIDIC
DIPEPTIDASE-LIKE
PROTEIN

(Homo sapiens) 		PF02225
(PA)
PF04253
(TFR_dimer)
PF04389
(Peptidase_M28) 		4 ALA A  71
SER A 346
SER A 412
PRO A 379
 None
None
None
ZN  A 802 ( 4.7A)
 1.08A 5c6pA-4tweA:
undetectable		 5c6pA-4tweA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ufc GH95

(Bacteroides
ovatus) 		PF14498
(Glyco_hyd_65N_2) 		4 ALA A 382
GLN A 345
SER A 343
PRO A 393
 None
 1.05A 5c6pA-4ufcA:
undetectable		 5c6pA-4ufcA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x1z VP1

(Rabbit
hemorrhagic
disease virus) 		PF00915
(Calici_coat) 		4 ALA A 397
SER A 319
SER A 329
PRO A 447
 None
None
None
NA  A 605 (-4.5A)
 0.94A 5c6pA-4x1zA:
undetectable		 5c6pA-4x1zA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9x DEGV
DOMAIN-CONTAINING
PROTEIN MW1315

(Staphylococcus
aureus) 		PF02645
(DegV) 		4 ALA A 265
SER A 264
GLN A  41
SER A  10
 None
EDO  A 302 (-2.7A)
None
None
 0.87A 5c6pA-4x9xA:
undetectable		 5c6pA-4x9xA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xky DIHYDRODIPICOLINATE
SYNTHASE

(Bacteroides
thetaiotaomicron) 		PF00701
(DHDPS) 		4 ALA A 106
GLN A  52
SER A  51
ASP A  82
 None
 0.95A 5c6pA-4xkyA:
undetectable		 5c6pA-4xkyA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah5 LEUCINE--TRNA LIGASE

(Agrobacterium
tumefaciens) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF13603
(tRNA-synt_1_2) 		4 SER A  43
SER A 105
ASP A 582
PRO A 583
 None
 1.17A 5c6pA-5ah5A:
undetectable		 5c6pA-5ah5A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aog CATIONIC PEROXIDASE
SPC4

(Sorghum bicolor) 		PF00141
(peroxidase) 		4 ALA A 206
GLN A 302
SER A 301
ASP A 307
 None
 1.14A 5c6pA-5aogA:
undetectable		 5c6pA-5aogA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5awm STRESS-ACTIVATED
PROTEIN KINASE JNK

(Drosophila
melanogaster) 		PF00069
(Pkinase) 		4 ALA A 290
SER A 291
GLN A 284
ASP A 281
 None
 1.22A 5c6pA-5awmA:
undetectable		 5c6pA-5awmA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cwi DESIGNED HELICAL
REPEAT PROTEIN

(synthetic
construct) 		no annotation 4 ALA A 154
GLN A  92
SER A  91
ASP A 150
 None
 1.23A 5c6pA-5cwiA:
3.0		 5c6pA-5cwiA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzs SHIKIMATE
DEHYDROGENASE
(NADP(+))

(Clostridioides
difficile) 		PF08501
(Shikimate_dh_N) 		4 ALA A 133
SER A 130
SER A 160
ASP A 139
 None
 1.22A 5c6pA-5dzsA:
undetectable		 5c6pA-5dzsA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5efv PHI ETA ORF 56-LIKE
PROTEIN

(Staphylococcus
virus 11) 		no annotation 4 ALA A 227
SER A 267
GLN A 165
SER A 166
 None
 1.07A 5c6pA-5efvA:
undetectable		 5c6pA-5efvA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fn1 COAT PROTEIN

(Pepino mosaic
virus) 		PF00286
(Flexi_CP) 		4 ALA A  95
SER A  94
GLN A 203
ASP A 163
 None
U  B   1 ( 3.1A)
U  B   3 ( 2.6A)
U  B   2 ( 4.1A)
 1.13A 5c6pA-5fn1A:
undetectable		 5c6pA-5fn1A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hc8 PRENYLTRANSFERENCE
FOR PROTEIN

(Lavandula
lanata) 		PF01255
(Prenyltransf) 		4 ALA A 250
SER A  84
ASP A 277
PRO A 276
 None
 1.14A 5c6pA-5hc8A:
undetectable		 5c6pA-5hc8A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j9c PEROXIREDOXIN ASP F3

(Aspergillus
fumigatus) 		PF08534
(Redoxin) 		4 ALA A  39
SER A  40
ASP A 114
PRO A 115
 None
 1.16A 5c6pA-5j9cA:
undetectable		 5c6pA-5j9cA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j9c PEROXIREDOXIN ASP F3

(Aspergillus
fumigatus) 		PF08534
(Redoxin) 		4 ALA A  39
SER A  40
SER A 122
ASP A 114
 None
 1.07A 5c6pA-5j9cA:
undetectable		 5c6pA-5j9cA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jzw AEROLYSIN

(Aeromonas
hydrophila) 		PF01117
(Aerolysin)
PF03440
(APT) 		4 ALA A 423
GLN A 212
SER A 213
PRO A 419
 None
 1.17A 5c6pA-5jzwA:
undetectable		 5c6pA-5jzwA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lm7 TRANSCRIPTION
TERMINATION/ANTITERM
INATION PROTEIN NUSA

(Escherichia
coli) 		PF00575
(S1)
PF08529
(NusA_N)
PF13184
(KH_5) 		4 ALA A 308
SER A 295
GLN A 349
ASP A 342
 None
 1.17A 5c6pA-5lm7A:
undetectable		 5c6pA-5lm7A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nri D-ALANINE--D-ALANINE
LIGASE

(Burkholderia
pseudomallei) 		no annotation 4 ALA A  13
SER A  26
ASP A  48
PRO A  49
 None
 1.19A 5c6pA-5nriA:
undetectable		 5c6pA-5nriA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ocy ACPA E4 FAB FRAGMENT
- HEAVY CHAIN
ACPA E4 FAB FRAGMENT
- LIGHT CHAIN

(Homo sapiens) 		no annotation 4 ALA L  44
SER L  43
ASP H 108
PRO H 109
 None
 1.20A 5c6pA-5ocyL:
undetectable		 5c6pA-5ocyL:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8j CYCLIC GMP-AMP
SYNTHASE

(Homo sapiens) 		PF03281
(Mab-21) 		4 ALA A 222
SER A 221
SER A 435
ASP A 227
 None
 1.05A 5c6pA-5v8jA:
undetectable		 5c6pA-5v8jA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vmb SERINE
HYDROXYMETHYLTRANSFE
RASE

(Acinetobacter
baumannii) 		PF00464
(SHMT) 		4 ALA A 148
SER A 321
ASP A 351
PRO A 352
 None
 1.14A 5c6pA-5vmbA:
undetectable		 5c6pA-5vmbA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w0m TERMINAL
URIDYLYLTRANSFERASE
7

(Homo sapiens) 		PF00098
(zf-CCHC)
PF03828
(PAP_assoc) 		4 ALA A1172
SER A1170
ASP A1280
PRO A1281
 None
SO4  A1401 (-2.8A)
None
None
 0.99A 5c6pA-5w0mA:
undetectable		 5c6pA-5w0mA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w40 POPP2 PROTEIN

(Ralstonia
solanacearum) 		PF03421
(Acetyltransf_14) 		4 SER A 447
SER A 317
ASP A 182
PRO A 183
 None
COA  A 502 (-4.8A)
None
None
 1.16A 5c6pA-5w40A:
undetectable		 5c6pA-5w40A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yj6 DOCKERIN TYPE I
REPEAT-CONTAINING
PROTEIN

(Ruminiclostridium
thermocellum) 		no annotation 4 ALA A 432
GLN A 587
ASP A 147
PRO A 148
 None
 1.11A 5c6pA-5yj6A:
undetectable		 5c6pA-5yj6A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6acd -

(-) 		no annotation 4 ALA A 857
SER A 861
ASP A 790
PRO A 791
 None
 1.18A 5c6pA-6acdA:
undetectable		 5c6pA-6acdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cc4 SOLUBLE CYTOCHROME
B562, LIPID II
FLIPPASE MURJ
CHIMERA

(Escherichia
coli) 		no annotation 4 ALA A  69
SER A  73
SER A -47
ASP A -52
 None
 1.10A 5c6pA-6cc4A:
8.9		 5c6pA-6cc4A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f49 -

(-) 		no annotation 4 ALA A  94
GLN A  65
ASP A 123
PRO A 124
 None
 1.09A 5c6pA-6f49A:
undetectable		 5c6pA-6f49A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6frv GLUCOAMYLASE

(Aspergillus
niger) 		no annotation 4 ALA A 191
SER A 188
SER A 233
ASP A 238
 None
 1.20A 5c6pA-6frvA:
undetectable		 5c6pA-6frvA:
10.91