SIMILAR PATTERNS OF AMINO ACIDS FOR 5C0O_G_SAMG301_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dot DUCK OVOTRANSFERRIN

(Anas
platyrhynchos) 		PF00405
(Transferrin) 		3 GLU A  80
HIS A 250
ASP A 302
 None
FE  A 687 (-3.2A)
None
 0.81A 5c0oG-1dotA:
undetectable		 5c0oG-1dotA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f0x D-LACTATE
DEHYDROGENASE

(Escherichia
coli) 		PF01565
(FAD_binding_4)
PF09330
(Lact-deh-memb) 		3 GLU A 172
HIS A 222
ASP A 248
 None
 0.82A 5c0oG-1f0xA:
undetectable		 5c0oG-1f0xA:
17.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1i9g HYPOTHETICAL PROTEIN
RV2118C

(Mycobacterium
tuberculosis) 		PF08704
(GCD14)
PF14801
(GCD14_N) 		3 GLU A 131
HIS A 136
ASP A 178
 SAM  A 301 (-2.6A)
SAM  A 301 (-3.7A)
SAM  A 301 (-3.4A)
 0.29A 5c0oG-1i9gA:
28.6		 5c0oG-1i9gA:
38.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iu4 MICROBIAL
TRANSGLUTAMINASE

(Streptomyces
mobaraensis) 		PF09017
(Transglut_prok) 		3 GLU A  28
HIS A 289
ASP A  18
 None
 0.69A 5c0oG-1iu4A:
undetectable		 5c0oG-1iu4A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE

(Pyrococcus
furiosus) 		PF00152
(tRNA-synt_2) 		3 GLU A 101
HIS A 110
ASP A  52
 None
 0.81A 5c0oG-1nnhA:
undetectable		 5c0oG-1nnhA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nnt OVOTRANSFERRIN

(Gallus gallus) 		PF00405
(Transferrin) 		3 GLU A  80
HIS A 250
ASP A 302
 None
FE  A 333 ( 3.5A)
None
 0.80A 5c0oG-1nntA:
undetectable		 5c0oG-1nntA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qvp DIPHTHERIA TOXIN
REPRESSOR

(Corynebacterium
diphtheriae) 		PF04023
(FeoA) 		3 GLU A 212
HIS A 201
ASP A 177
 None
 0.81A 5c0oG-1qvpA:
undetectable		 5c0oG-1qvpA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r8g HYPOTHETICAL PROTEIN
YBDK

(Escherichia
coli) 		PF04107
(GCS2) 		3 GLU A 237
HIS A 136
ASP A 226
 None
 0.76A 5c0oG-1r8gA:
undetectable		 5c0oG-1r8gA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uf2 CORE PROTEIN P3

(Rice dwarf
virus) 		PF09231
(RDV-p3) 		3 GLU A 115
HIS A 110
ASP A 913
 None
 0.57A 5c0oG-1uf2A:
undetectable		 5c0oG-1uf2A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6m GALACTOSE-BINDING
LECTIN

(Arachis
hypogaea) 		PF00139
(Lectin_legB) 		3 GLU A 121
HIS A 137
ASP A 146
 MN  A1238 (-2.7A)
MN  A1238 (-3.5A)
None
 0.87A 5c0oG-1v6mA:
undetectable		 5c0oG-1v6mA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w0h 3'-5' EXONUCLEASE
ERI1

(Homo sapiens) 		PF00929
(RNase_T) 		3 GLU A 136
HIS A 293
ASP A 230
 AMP  A1002 ( 2.6A)
AMP  A1002 (-3.9A)
None
 0.77A 5c0oG-1w0hA:
undetectable		 5c0oG-1w0hA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x3l HYPOTHETICAL PROTEIN
PH0495

(Pyrococcus
horikoshii) 		PF05161
(MOFRL)
PF13660
(DUF4147) 		3 GLU A 346
HIS A 403
ASP A 299
 None
 0.77A 5c0oG-1x3lA:
4.8		 5c0oG-1x3lA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6t APOPTOTIC PROTEASE
ACTIVATING FACTOR 1

(Homo sapiens) 		PF00619
(CARD)
PF00931
(NB-ARC) 		3 GLU A  78
HIS A  77
ASP A 427
 None
 0.60A 5c0oG-1z6tA:
2.1		 5c0oG-1z6tA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zbu 3'-5' EXONUCLEASE
ERI1

(Homo sapiens) 		PF00929
(RNase_T) 		3 GLU A 136
HIS A 293
ASP A 230
 AMP  A1002 ( 2.7A)
AMP  A1002 (-4.0A)
None
 0.79A 5c0oG-1zbuA:
undetectable		 5c0oG-1zbuA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zoq INTERFERON
REGULATORY FACTOR 3

(Homo sapiens) 		PF10401
(IRF-3) 		3 GLU A 310
HIS A 290
ASP A 314
 None
 0.64A 5c0oG-1zoqA:
undetectable		 5c0oG-1zoqA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a8n CYTIDINE AND
DEOXYCYTIDYLATE
DEAMINASE

(Agrobacterium
tumefaciens) 		PF14437
(MafB19-deam) 		3 GLU A  55
HIS A  53
ASP A 104
 ZN  A 301 ( 4.0A)
ZN  A 301 (-3.1A)
None
 0.83A 5c0oG-2a8nA:
undetectable		 5c0oG-2a8nA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aw5 NADP-DEPENDENT MALIC
ENZYME

(Homo sapiens) 		PF00390
(malic)
PF03949
(Malic_M) 		3 GLU A  83
HIS A  23
ASP A  80
 None
 0.85A 5c0oG-2aw5A:
4.1		 5c0oG-2aw5A:
18.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2b25 HYPOTHETICAL PROTEIN

(Homo sapiens) 		PF08704
(GCD14) 		3 GLU A 135
HIS A 140
ASP A 192
 SAM  A 601 (-2.9A)
SAM  A 601 (-4.0A)
SAM  A 601 (-3.5A)
 0.32A 5c0oG-2b25A:
26.8		 5c0oG-2b25A:
30.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o7p RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBD

(Escherichia
coli) 		PF00383
(dCMP_cyt_deam_1)
PF01872
(RibD_C) 		3 GLU A  52
HIS A  50
ASP A 102
 None
 0.74A 5c0oG-2o7pA:
undetectable		 5c0oG-2o7pA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qed HYDROXYACYLGLUTATHIO
NE HYDROLASE

(Salmonella
enterica) 		PF00753
(Lactamase_B)
PF16123
(HAGH_C) 		3 GLU A  79
HIS A  54
ASP A 127
 None
None
FE  A 252 ( 2.3A)
 0.84A 5c0oG-2qedA:
undetectable		 5c0oG-2qedA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xr1 CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
100 KD SUBUNIT

(Methanosarcina
mazei) 		PF07521
(RMMBL)
PF07650
(KH_2)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7) 		3 GLU A  15
HIS A  12
ASP A  26
 None
 0.79A 5c0oG-2xr1A:
3.2		 5c0oG-2xr1A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE

(Flavobacterium
sp.) 		PF00144
(Beta-lactamase) 		3 GLU A  41
HIS A  38
ASP A 252
 None
None
SO4  A 509 (-3.5A)
 0.79A 5c0oG-2zm2A:
undetectable		 5c0oG-2zm2A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zo4 METALLO-BETA-LACTAMA
SE FAMILY PROTEIN

(Thermus
thermophilus) 		PF00753
(Lactamase_B) 		3 GLU A  95
HIS A  71
ASP A 190
 None
None
ZN  A 319 ( 2.4A)
 0.87A 5c0oG-2zo4A:
undetectable		 5c0oG-2zo4A:
27.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a77 INTERFERON
REGULATORY FACTOR 3

(Homo sapiens) 		PF10401
(IRF-3) 		3 GLU A 310
HIS A 290
ASP A 314
 None
 0.68A 5c0oG-3a77A:
undetectable		 5c0oG-3a77A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aco PROTEIN KINASE C AND
CASEIN KINASE
SUBSTRATE IN NEURONS
PROTEIN 2

(Homo sapiens) 		PF00611
(FCH) 		3 GLU A  52
HIS A  97
ASP A 256
 None
 0.86A 5c0oG-3acoA:
undetectable		 5c0oG-3acoA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3act CELLOBIOSE
PHOSPHORYLASE

(Cellulomonas
gilvus) 		PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36) 		3 GLU A 517
HIS A 478
ASP A 574
 None
 0.81A 5c0oG-3actA:
undetectable		 5c0oG-3actA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ago RIBONUCLEASE U2

(Ustilago
sphaerogena) 		PF00545
(Ribonuclease) 		3 GLU A  62
HIS A  41
ASP A 108
 3AM  A 115 (-2.9A)
3AM  A 115 (-3.8A)
3AM  A 115 (-2.9A)
 0.49A 5c0oG-3agoA:
undetectable		 5c0oG-3agoA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cax UNCHARACTERIZED
PROTEIN PF0695

(Pyrococcus
furiosus) 		PF01814
(Hemerythrin)
PF13596
(PAS_10) 		3 GLU A 304
HIS A 301
ASP A 344
 None
 0.74A 5c0oG-3caxA:
undetectable		 5c0oG-3caxA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cc1 PUTATIVE
ALPHA-N-ACETYLGALACT
OSAMINIDASE

(Bacillus
halodurans) 		PF16499
(Melibiase_2) 		3 GLU A 299
HIS A 421
ASP A 245
 None
 0.85A 5c0oG-3cc1A:
undetectable		 5c0oG-3cc1A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6b GLUTARYL-COA
DEHYDROGENASE

(Burkholderia
pseudomallei) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		3 GLU A  88
HIS A  30
ASP A  15
 None
 0.69A 5c0oG-3d6bA:
undetectable		 5c0oG-3d6bA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dy5 ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN

(Plexaura
homomalla) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		3 GLU A 648
HIS A 653
ASP A 640
 None
 0.87A 5c0oG-3dy5A:
undetectable		 5c0oG-3dy5A:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE

(Bifidobacterium
adolescentis) 		PF02811
(PHP) 		3 GLU A 230
HIS A  17
ASP A 205
 None
FE  A 303 (-3.3A)
None
 0.81A 5c0oG-3e0fA:
undetectable		 5c0oG-3e0fA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e4f AMINOGLYCOSIDE
N3-ACETYLTRANSFERASE

(Bacillus
anthracis) 		PF02522
(Antibiotic_NAT) 		3 GLU A 186
HIS A 183
ASP A 220
 None
 0.83A 5c0oG-3e4fA:
2.6		 5c0oG-3e4fA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3etc AMP-BINDING PROTEIN

(Methanosarcina
acetivorans) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 GLU A 398
HIS A 432
ASP A 385
 None
 0.76A 5c0oG-3etcA:
3.9		 5c0oG-3etcA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f2b DNA-DIRECTED DNA
POLYMERASE III ALPHA
CHAIN

(Geobacillus
kaustophilus) 		PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		3 GLU A 698
HIS A 346
ASP A 671
 None
MG  A   7 (-3.4A)
None
 0.79A 5c0oG-3f2bA:
undetectable		 5c0oG-3f2bA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fzg 16S RRNA METHYLASE

(Escherichia
coli) 		PF07091
(FmrO) 		3 GLU A 142
HIS A  83
ASP A 112
 SAM  A 300 ( 4.6A)
SAM  A 300 (-4.4A)
None
 0.80A 5c0oG-3fzgA:
10.3		 5c0oG-3fzgA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gw4 UNCHARACTERIZED
PROTEIN

(Deinococcus
radiodurans) 		PF13424
(TPR_12) 		3 GLU A  93
HIS A  71
ASP A 103
 None
 0.58A 5c0oG-3gw4A:
undetectable		 5c0oG-3gw4A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hf1 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B

(Homo sapiens) 		PF00268
(Ribonuc_red_sm) 		3 GLU A 194
HIS A 231
ASP A 100
 FE  A 401 (-2.5A)
FE  A 401 (-3.2A)
None
 0.84A 5c0oG-3hf1A:
undetectable		 5c0oG-3hf1A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hf1 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT M2 B

(Homo sapiens) 		PF00268
(Ribonuc_red_sm) 		3 GLU A 228
HIS A 231
ASP A 100
 FE  A 401 (-2.9A)
FE  A 401 (-3.2A)
None
 0.82A 5c0oG-3hf1A:
undetectable		 5c0oG-3hf1A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iu0 PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE

(Streptomyces
mobaraensis) 		PF09017
(Transglut_prok) 		3 GLU A  74
HIS A 335
ASP A  64
 None
 0.77A 5c0oG-3iu0A:
undetectable		 5c0oG-3iu0A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iu5 PROTEIN POLYBROMO-1

(Homo sapiens) 		PF00439
(Bromodomain) 		3 GLU A  52
HIS A  51
ASP A  59
 None
 0.84A 5c0oG-3iu5A:
undetectable		 5c0oG-3iu5A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ivr PUTATIVE
LONG-CHAIN-FATTY-ACI
D COA LIGASE

(Rhodopseudomonas
palustris) 		PF00501
(AMP-binding) 		3 GLU A 350
HIS A 379
ASP A 337
 None
 0.75A 5c0oG-3ivrA:
2.6		 5c0oG-3ivrA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfo NUCLEOPORIN NUP133

(Saccharomyces
cerevisiae) 		no annotation 3 GLU A1012
HIS A1060
ASP A1067
 None
 0.55A 5c0oG-3kfoA:
undetectable		 5c0oG-3kfoA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lgx D-ALANINE--POLY(PHOS
PHORIBITOL) LIGASE
SUBUNIT 1

(Streptococcus
pyogenes) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 GLU A 345
HIS A 378
ASP A 332
 None
 0.75A 5c0oG-3lgxA:
2.2		 5c0oG-3lgxA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m3w PROTEIN KINASE C AND
CASEIN KINASE II
SUBSTRATE PROTEIN 3

(Mus musculus) 		PF00611
(FCH) 		3 GLU A  50
HIS A  95
ASP A 254
 None
 0.86A 5c0oG-3m3wA:
undetectable		 5c0oG-3m3wA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mc2 INHIBITOR OF
CARBONIC ANHYDRASE

(Mus musculus) 		PF00405
(Transferrin) 		3 GLU A  83
HIS A 249
ASP A 297
 None
 0.78A 5c0oG-3mc2A:
undetectable		 5c0oG-3mc2A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6o GUANINE NUCLEOTIDE
EXCHANGE FACTOR

(Legionella
pneumophila) 		PF14860
(DrrA_P4M) 		3 GLU A 631
HIS A 496
ASP A 577
 None
 0.79A 5c0oG-3n6oA:
undetectable		 5c0oG-3n6oA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3om5 LEVANSUCRASE

(Bacillus
megaterium) 		PF02435
(Glyco_hydro_68) 		3 GLU A 327
HIS A 266
ASP A 330
 None
 0.87A 5c0oG-3om5A:
undetectable		 5c0oG-3om5A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p2c PUTATIVE GLYCOSYL
HYDROLASE

(Bacteroides
ovatus) 		PF06824
(Glyco_hydro_125) 		3 GLU A 340
HIS A 348
ASP A 273
 None
 0.76A 5c0oG-3p2cA:
undetectable		 5c0oG-3p2cA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8t ASNS-LIKE
ASPARAGINYL-TRNA
SYNTHETASE RELATED
PROTEIN

(Pyrococcus
abyssi) 		PF00152
(tRNA-synt_2) 		3 GLU A 101
HIS A 110
ASP A  52
 None
 0.84A 5c0oG-3p8tA:
undetectable		 5c0oG-3p8tA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qde CELLOBIOSE
PHOSPHORYLASE

(Ruminiclostridium
thermocellum) 		PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36) 		3 GLU A 510
HIS A 471
ASP A 567
 None
 0.82A 5c0oG-3qdeA:
undetectable		 5c0oG-3qdeA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s4d LACTOSE
PHOSPHORYLASE

(Cellulomonas
uda) 		PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36) 		3 GLU A 517
HIS A 478
ASP A 574
 None
 0.83A 5c0oG-3s4dA:
undetectable		 5c0oG-3s4dA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tfw PUTATIVE
O-METHYLTRANSFERASE

(Klebsiella
pneumoniae) 		PF01596
(Methyltransf_3) 		3 GLU A  93
HIS A  98
ASP A 141
 None
 0.47A 5c0oG-3tfwA:
18.3		 5c0oG-3tfwA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u7i FMN-DEPENDENT
NADH-AZOREDUCTASE 1

(Bacillus
anthracis) 		PF02525
(Flavodoxin_2) 		3 GLU A 161
HIS A 164
ASP A 154
 None
CL  A 222 (-4.8A)
None
 0.64A 5c0oG-3u7iA:
undetectable		 5c0oG-3u7iA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uaq LBPB B-LOBE

(Moraxella bovis) 		PF01298
(TbpB_B_D)
PF17484
(TbpB_A) 		3 GLU A  78
HIS A  75
ASP A 214
 None
 0.73A 5c0oG-3uaqA:
undetectable		 5c0oG-3uaqA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3urh DIHYDROLIPOYL
DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		3 GLU A  57
HIS A  60
ASP A 396
 None
 0.65A 5c0oG-3urhA:
3.0		 5c0oG-3urhA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wv4 NON-RIBOSOMAL
PEPTIDE SYNTHETASE

(Streptomyces
halstedii) 		PF00501
(AMP-binding) 		3 GLU A 373
HIS A 408
ASP A 360
 None
 0.74A 5c0oG-3wv4A:
2.6		 5c0oG-3wv4A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ae5 SIGNAL TRANSDUCTION
PROTEIN TRAP

(Staphylococcus
aureus) 		no annotation 3 GLU A  39
HIS A  24
ASP A  42
 None
 0.64A 5c0oG-4ae5A:
undetectable		 5c0oG-4ae5A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4atf BETA-AGARASE B

(Zobellia
galactanivorans) 		PF00722
(Glyco_hydro_16) 		3 GLU A 184
HIS A 215
ASP A 173
 GAL  A1357 (-4.1A)
GAL  A1357 (-3.3A)
GAL  A1357 (-2.8A)
 0.86A 5c0oG-4atfA:
undetectable		 5c0oG-4atfA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bfr PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC S
SUBUNIT BETA ISOFORM

(Mus musculus) 		PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd) 		3 GLU A1008
HIS A 934
ASP A 807
 None
None
J82  A2000 ( 4.9A)
 0.72A 5c0oG-4bfrA:
undetectable		 5c0oG-4bfrA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bws THIOREDOXIN-LIKE
PROTEIN 4A

(Homo sapiens) 		PF02966
(DIM1) 		3 GLU A  65
HIS A   9
ASP A  33
 None
 0.73A 5c0oG-4bwsA:
undetectable		 5c0oG-4bwsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3o HYDROGENASE-1 LARGE
SUBUNIT

(Salmonella
enterica) 		PF00374
(NiFeSe_Hases) 		3 GLU A 461
HIS A 115
ASP A 577
 None
 0.81A 5c0oG-4c3oA:
undetectable		 5c0oG-4c3oA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2

(Neurospora
crassa) 		PF00929
(RNase_T)
PF13423
(UCH_1) 		3 GLU A 497
HIS A 556
ASP A 481
 None
 0.68A 5c0oG-4czwA:
undetectable		 5c0oG-4czwA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ex4 MALATE SYNTHASE G

(Mycobacterium
leprae) 		PF01274
(Malate_synthase) 		3 GLU A 264
HIS A 239
ASP A 107
 None
 0.82A 5c0oG-4ex4A:
undetectable		 5c0oG-4ex4A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h5y LIDA PROTEIN,
SUBSTRATE OF THE
DOT/ICM SYSTEM

(Legionella
pneumophila) 		no annotation 3 GLU A 160
HIS A 157
ASP A  81
 None
 0.84A 5c0oG-4h5yA:
undetectable		 5c0oG-4h5yA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hy3 PHOSPHOGLYCERATE
OXIDOREDUCTASE

(Rhizobium etli) 		PF02826
(2-Hacid_dh_C) 		3 GLU A 273
HIS A 292
ASP A 247
 None
 0.77A 5c0oG-4hy3A:
4.9		 5c0oG-4hy3A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ijr D-ARABINOSE
DEHYDROGENASE
[NAD(P)+] HEAVY
CHAIN

(Saccharomyces
cerevisiae) 		PF00248
(Aldo_ket_red) 		3 GLU A  72
HIS A  44
ASP A 141
 None
 0.87A 5c0oG-4ijrA:
undetectable		 5c0oG-4ijrA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j3z MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Jannaschia sp.
CCS1) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 GLU A 335
HIS A 310
ASP A 168
 None
 0.84A 5c0oG-4j3zA:
undetectable		 5c0oG-4j3zA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nqf NUCLEOTIDYLTRANSFERA
SE

(Agrobacterium
fabrum) 		PF05168
(HEPN) 		3 GLU A 199
HIS A 217
ASP A 170
 None
 0.86A 5c0oG-4nqfA:
undetectable		 5c0oG-4nqfA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oet PUTATIVE PEPTIDE
ABC-TRANSPORT SYSTEM
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Campylobacter
jejuni) 		PF00496
(SBP_bac_5) 		3 GLU A  12
HIS A 481
ASP A 218
 None
 0.57A 5c0oG-4oetA:
undetectable		 5c0oG-4oetA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 GLU A 759
HIS A 761
ASP A 727
 None
NAG  A1109 (-4.2A)
None
 0.81A 5c0oG-4pj6A:
undetectable		 5c0oG-4pj6A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pl7 ACTIN,THYMOSIN
BETA-4

(Homo sapiens;
Komagataella
phaffii) 		PF00022
(Actin)
PF01290
(Thymosin) 		3 GLU A 259
HIS A 263
ASP A 222
 None
 0.87A 5c0oG-4pl7A:
undetectable		 5c0oG-4pl7A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgk UNCHARACTERIZED
PROTEIN

(Yersinia pestis) 		PF07350
(DUF1479) 		3 GLU A 343
HIS A 267
ASP A 325
 None
 0.86A 5c0oG-4rgkA:
undetectable		 5c0oG-4rgkA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4whx BRANCHED-CHAIN-AMINO
-ACID TRANSAMINASE

(Burkholderia
pseudomallei) 		PF01063
(Aminotran_4) 		3 GLU A  39
HIS A  59
ASP A 219
 LLP  A 161 ( 3.9A)
LLP  A 161 ( 4.9A)
None
 0.67A 5c0oG-4whxA:
undetectable		 5c0oG-4whxA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9e DEOXYGUANOSINETRIPHO
SPHATE
TRIPHOSPHOHYDROLASE

(Escherichia
coli) 		PF01966
(HD) 		3 GLU A 129
HIS A 126
ASP A 118
 None
None
MG  A1000 ( 3.7A)
 0.81A 5c0oG-4x9eA:
undetectable		 5c0oG-4x9eA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xt8 RV2671

(Mycobacterium
tuberculosis) 		PF01872
(RibD_C) 		3 GLU A  76
HIS A 105
ASP A  33
 None
 0.87A 5c0oG-4xt8A:
undetectable		 5c0oG-4xt8A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b7i CRISPR-ASSOCIATED
NUCLEASE/HELICASE
CAS3 SUBTYPE
I-F/YPEST

(Pseudomonas
aeruginosa) 		no annotation 3 GLU A 150
HIS A 221
ASP A 145
 None
CA  A1101 (-3.5A)
None
 0.80A 5c0oG-5b7iA:
2.4		 5c0oG-5b7iA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7q ACYL-COA SYNTHETASE

(Streptomyces
platensis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 GLU A 359
HIS A 388
ASP A 346
 None
 0.79A 5c0oG-5e7qA:
undetectable		 5c0oG-5e7qA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e8k GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE 10,
MITOCHONDRIAL

(Arabidopsis
thaliana) 		PF00348
(polyprenyl_synt) 		3 GLU A  81
HIS A  84
ASP A  50
 None
 0.68A 5c0oG-5e8kA:
undetectable		 5c0oG-5e8kA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eio N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE/N-ACET
YL-GAMMA-AMINOADIPYL
-PHOSPHATE REDUCTASE

(Thermus
thermophilus) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		3 GLU A 212
HIS A 209
ASP A 100
 None
 0.81A 5c0oG-5eioA:
3.2		 5c0oG-5eioA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis) 		PF13402
(Peptidase_M60)
PF17291
(M60-like_N) 		3 GLU A 282
HIS A 285
ASP A 247
 None
 0.76A 5c0oG-5ev7A:
undetectable		 5c0oG-5ev7A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5giv CARBOXYPEPTIDASE 1

(Deinococcus
radiodurans) 		PF02074
(Peptidase_M32) 		3 GLU A 303
HIS A 266
ASP A 351
 None
ZN  A 601 (-3.4A)
None
 0.64A 5c0oG-5givA:
undetectable		 5c0oG-5givA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gms ESTERASE

(uncultured
bacterium) 		PF07859
(Abhydrolase_3) 		3 GLU A 239
HIS A 269
ASP A 244
 None
 0.85A 5c0oG-5gmsA:
3.4		 5c0oG-5gmsA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5guh PIWI

(Bombyx mori) 		PF02170
(PAZ)
PF02171
(Piwi) 		3 GLU A 578
HIS A 573
ASP A 605
 None
 0.60A 5c0oG-5guhA:
2.0		 5c0oG-5guhA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gy6 RIBONUCLEASE T1

(Hericium
erinaceus) 		PF00545
(Ribonuclease) 		3 GLU A  53
HIS A  34
ASP A  93
 ZN  A 201 (-2.0A)
ZN  A 201 (-3.1A)
None
 0.78A 5c0oG-5gy6A:
undetectable		 5c0oG-5gy6A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jem INTERFERON
REGULATORY FACTOR 3

(Homo sapiens) 		PF10401
(IRF-3) 		3 GLU A 310
HIS A 290
ASP A 314
 None
 0.59A 5c0oG-5jemA:
undetectable		 5c0oG-5jemA:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjq AMP-DEPENDENT
SYNTHETASE AND
LIGASE

(Streptomyces
sp. ML694-90F3) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 GLU A 417
HIS A 342
ASP A 326
 None
 0.71A 5c0oG-5jjqA:
4.4		 5c0oG-5jjqA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jpz SQUAMOUS CELL
CARCINOMA ANTIGEN
RECOGNIZED BY
T-CELLS 3

(Homo sapiens) 		no annotation 3 GLU A 518
HIS A 526
ASP A 497
 None
 0.66A 5c0oG-5jpzA:
undetectable		 5c0oG-5jpzA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kgo FLAGELLAR BRAKE
PROTEIN YCGR

(Klebsiella
pneumoniae) 		no annotation 3 GLU D  28
HIS D  69
ASP D 140
 None
C2E  D 301 (-3.6A)
C2E  D 302 (-3.7A)
 0.68A 5c0oG-5kgoD:
undetectable		 5c0oG-5kgoD:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kk5 CRISPR-ASSOCIATED
ENDONUCLEASE CPF1

(Acidaminococcus
sp. BV3L6) 		no annotation 3 GLU A1099
HIS A1096
ASP A1207
 None
 0.84A 5c0oG-5kk5A:
undetectable		 5c0oG-5kk5A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oas MALATE SYNTHASE G

(Pseudomonas
aeruginosa) 		no annotation 3 GLU A 264
HIS A 239
ASP A 107
 None
 0.77A 5c0oG-5oasA:
undetectable		 5c0oG-5oasA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oo7 SLA2

(Chaetomium
thermophilum) 		no annotation 3 GLU A 135
HIS A 133
ASP A 153
 None
 0.80A 5c0oG-5oo7A:
undetectable		 5c0oG-5oo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sy5 ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
NEURONAL PAS
DOMAIN-CONTAINING
PROTEIN 1

(Mus musculus;
Mus musculus) 		PF00010
(HLH)
PF00989
(PAS)
PF14598
(PAS_11)
PF00010
(HLH)
PF00989
(PAS)
PF08447
(PAS_3) 		3 GLU A 223
HIS B 302
ASP A 217
 None
 0.81A 5c0oG-5sy5A:
undetectable		 5c0oG-5sy5A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tge PHAGE TERMINASE
LARGE SUBUNIT

(Thermus virus
P74-26) 		PF17289
(Terminase_6C) 		3 GLU A 404
HIS A 427
ASP A 294
 None
 0.87A 5c0oG-5tgeA:
undetectable		 5c0oG-5tgeA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj8 ORIGIN RECOGNITION
COMPLEX SUBUNIT 2

(Homo sapiens) 		PF04084
(ORC2) 		3 GLU E 387
HIS E 306
ASP E 333
 None
 0.82A 5c0oG-5uj8E:
undetectable		 5c0oG-5uj8E:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4

(Mus musculus) 		no annotation 3 GLU A 124
HIS A 156
ASP A 116
 None
 0.83A 5c0oG-5wnmA:
undetectable		 5c0oG-5wnmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wzk PUMILIO HOMOLOG 23

(Arabidopsis
thaliana) 		no annotation 3 GLU A 330
HIS A 327
ASP A 359
 G  B   6 ( 3.3A)
A  B   7 ( 3.3A)
None
 0.83A 5c0oG-5wzkA:
undetectable		 5c0oG-5wzkA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y7o UGGT

(Thermomyces
dupontii) 		PF06427
(UDP-g_GGTase) 		3 GLU A  93
HIS A  95
ASP A  66
 None
 0.75A 5c0oG-5y7oA:
undetectable		 5c0oG-5y7oA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6axe MALATE SYNTHASE G

(Mycobacterium
marinum) 		PF01274
(Malate_synthase) 		3 GLU A 263
HIS A 238
ASP A 107
 None
 0.83A 5c0oG-6axeA:
undetectable		 5c0oG-6axeA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6blj SERINE-TRNA LIGASE

(Naegleria
fowleri) 		no annotation 3 GLU A 449
HIS A 183
ASP A 391
 None
 0.78A 5c0oG-6bljA:
undetectable		 5c0oG-6bljA:
undetectable