SIMILAR PATTERNS OF AMINO ACIDS FOR 5BPH_D_ACTD403_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e08 CYTOCHROME C553

(Desulfovibrio
vulgaris) 		PF00034
(Cytochrom_C) 		4 TYR E   7
GLY E  33
SER E  77
LEU E  79
 HEM  E  80 ( 4.9A)
None
None
None
 1.25A 5bphD-1e08E:
undetectable		 5bphD-1e08E:
15.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ehi D-ALANINE:D-LACTATE
LIGASE

(Leuconostoc
mesenteroides) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 TYR A 255
LYS A 260
GLY A 322
SER A 327
 None
PHY  A 782 ( 2.6A)
PHY  A 782 (-3.5A)
PHY  A 782 (-2.6A)
 0.72A 5bphD-1ehiA:
35.2		 5bphD-1ehiA:
31.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1iov D-ALA:D-ALA LIGASE

(Escherichia
coli) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		6 TYR A 210
LYS A 215
ARG A 255
GLY A 276
SER A 281
LEU A 282
 None
POB  A 321 (-2.5A)
POB  A 321 (-3.2A)
POB  A 321 (-3.2A)
POB  A 321 ( 2.2A)
POB  A 321 (-3.7A)
 0.83A 5bphD-1iovA:
42.4		 5bphD-1iovA:
73.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iqr PHOTOLYASE

(Thermus
thermophilus) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		4 TYR A 256
ARG A 102
GLY A 101
SER A  96
 None
None
PO4  A 422 ( 4.7A)
PO4  A 422 (-2.6A)
 1.22A 5bphD-1iqrA:
2.3		 5bphD-1iqrA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jsd HAEMAGGLUTININ (HA1
CHAIN)

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 TYR A  78
GLY A 266
SER A 265
LEU A  41
 None
 1.21A 5bphD-1jsdA:
undetectable		 5bphD-1jsdA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1muu GDP-MANNOSE
6-DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		4 TYR A 211
GLY A  92
SER A  88
LEU A  94
 None
 0.93A 5bphD-1muuA:
4.0		 5bphD-1muuA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ryl HYPOTHETICAL PROTEIN
YFBM

(Escherichia
coli) 		PF08974
(DUF1877) 		4 TYR A   6
GLY A  36
SER A  35
LEU A  34
 None
 1.30A 5bphD-1rylA:
undetectable		 5bphD-1rylA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1to0 HYPOTHETICAL UPF0247
PROTEIN YYDA

(Bacillus
subtilis) 		PF02590
(SPOUT_MTase) 		4 LYS A  83
GLY A  80
SER A 126
LEU A 125
 None
 1.04A 5bphD-1to0A:
1.5		 5bphD-1to0A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uhz STAUFEN (RNA BINDING
PROTEIN) HOMOLOG 2

(Mus musculus) 		PF00035
(dsrm) 		4 TYR A  26
LYS A  62
GLY A   7
LEU A  12
 None
 0.98A 5bphD-1uhzA:
undetectable		 5bphD-1uhzA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vcj NEURAMINIDASE

(Influenza B
virus) 		PF00064
(Neur) 		4 ARG A 300
GLY A 351
SER A 366
LEU A 323
 None
 1.26A 5bphD-1vcjA:
undetectable		 5bphD-1vcjA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wa8 ESAT-6 LIKE PROTEIN
ESXB

(Mycobacterium
bovis) 		PF06013
(WXG100) 		4 LYS A  65
GLY A  22
SER A  21
LEU A  24
 None
 1.20A 5bphD-1wa8A:
undetectable		 5bphD-1wa8A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp. KM) 		PF00480
(ROK) 		4 TYR A 198
GLY A 223
SER A 225
LEU A 149
 None
 1.22A 5bphD-1woqA:
undetectable		 5bphD-1woqA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zch HYPOTHETICAL
OXIDOREDUCTASE YCND

(Bacillus
subtilis) 		PF00881
(Nitroreductase) 		4 ARG A 139
GLY A 136
SER A 159
LEU A 158
 None
FMN  A 301 (-3.5A)
FMN  A 301 ( 3.9A)
None
 0.94A 5bphD-1zchA:
undetectable		 5bphD-1zchA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2amc PHENYLALANYL-TRNA
SYNTHETASE ALPHA
CHAIN
PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Thermus
thermophilus;
Thermus
thermophilus) 		PF01409
(tRNA-synt_2d)
PF01409
(tRNA-synt_2d)
PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		4 TYR B 612
GLY B 595
SER A  94
LEU A  95
 None
 1.02A 5bphD-2amcB:
undetectable		 5bphD-2amcB:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ap1 PUTATIVE REGULATOR
PROTEIN

(Salmonella
enterica) 		PF00480
(ROK) 		4 TYR A 229
GLY A 254
SER A 256
LEU A 130
 None
 1.13A 5bphD-2ap1A:
undetectable		 5bphD-2ap1A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bru NAD(P)
TRANSHYDROGENASE
SUBUNIT ALPHA

(Escherichia
coli) 		PF01262
(AlaDh_PNT_C)
PF05222
(AlaDh_PNT_N) 		4 ARG A1140
GLY A1317
SER A1323
LEU A1319
 None
 1.26A 5bphD-2bruA:
3.5		 5bphD-2bruA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bvg 6-HYDROXY-D-NICOTINE
OXIDASE

(Paenarthrobacter
nicotinovorans) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 ARG A 317
GLY A 408
SER A 407
LEU A 400
 None
 1.26A 5bphD-2bvgA:
undetectable		 5bphD-2bvgA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c0k HEMOGLOBIN

(Gasterophilus
intestinalis) 		PF00042
(Globin) 		4 LYS A   1
GLY A  82
SER A  78
LEU A  77
 None
 1.12A 5bphD-2c0kA:
undetectable		 5bphD-2c0kA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cc3 PROTEIN VIRB8

(Agrobacterium
tumefaciens) 		PF04335
(VirB8) 		4 LYS A 201
ARG A 210
SER A 204
LEU A 205
 None
 1.23A 5bphD-2cc3A:
undetectable		 5bphD-2cc3A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d5r CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 7

(Homo sapiens) 		PF04857
(CAF1) 		4 LYS A  11
GLY A 222
SER A 229
LEU A 232
 None
 1.21A 5bphD-2d5rA:
undetectable		 5bphD-2d5rA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dgk GLUTAMATE
DECARBOXYLASE BETA

(Escherichia
coli) 		PF00282
(Pyridoxal_deC) 		4 TYR A 347
GLY A 210
SER A 246
LEU A 250
 None
 1.17A 5bphD-2dgkA:
undetectable		 5bphD-2dgkA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fv0 UNSATURATED
GLUCURONYL HYDROLASE

(Bacillus sp.
GL1) 		PF07470
(Glyco_hydro_88) 		4 TYR A 356
GLY A  90
SER A  94
LEU A  95
 None
 1.02A 5bphD-2fv0A:
undetectable		 5bphD-2fv0A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lef PROTEIN (LYMPHOID
ENHANCER-BINDING
FACTOR)

(Mus musculus) 		PF00505
(HMG_box) 		4 TYR A  52
LYS A  51
SER A  45
LEU A  44
 None
 1.31A 5bphD-2lefA:
undetectable		 5bphD-2lefA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lm4 SUCCINATE
DEHYDROGENASE
ASSEMBLY FACTOR 2,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF03937
(Sdh5) 		4 TYR A  61
GLY A  44
SER A  43
LEU A  42
 None
 1.13A 5bphD-2lm4A:
undetectable		 5bphD-2lm4A:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nx2 HYPOTHETICAL PROTEIN
YPSA

(Bacillus
subtilis) 		PF06908
(DUF1273) 		4 TYR A 164
GLY A  42
SER A   0
LEU A   1
 None
 1.25A 5bphD-2nx2A:
2.6		 5bphD-2nx2A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 ARG A 918
GLY A1036
SER A1033
LEU A1034
 None
 1.05A 5bphD-2p4iA:
undetectable		 5bphD-2p4iA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2paj PUTATIVE
CYTOSINE/GUANINE
DEAMINASE

(unidentified) 		PF01979
(Amidohydro_1) 		4 TYR A 410
LYS A 405
ARG A 396
GLY A 393
 None
 1.24A 5bphD-2pajA:
undetectable		 5bphD-2pajA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v8j PECTATE LYASE

(Yersinia
enterocolitica) 		PF06917
(Pectate_lyase_2) 		4 LYS A   5
ARG A 498
SER A  77
LEU A  76
 None
 1.23A 5bphD-2v8jA:
undetectable		 5bphD-2v8jA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vk4 PYRUVATE
DECARBOXYLASE

(Kluyveromyces
lactis) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 TYR A 299
GLY A 286
SER A 284
LEU A 217
 None
 1.18A 5bphD-2vk4A:
undetectable		 5bphD-2vk4A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vl8 CYTOTOXIN L

(Paeniclostridium
sordellii) 		PF12918
(TcdB_N)
PF12919
(TcdA_TcdB) 		4 TYR A 330
GLY A 292
SER A 509
LEU A 290
 None
 1.22A 5bphD-2vl8A:
undetectable		 5bphD-2vl8A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wsu PUTATIVE FIBER
PROTEIN

(Porcine
mastadenovirus
B) 		PF00337
(Gal-bind_lectin) 		4 ARG A 453
GLY A 455
SER A 431
LEU A 432
 None
 1.02A 5bphD-2wsuA:
undetectable		 5bphD-2wsuA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x04 POLYADENYLATE-BINDIN
G PROTEIN 1

(Homo sapiens) 		PF00658
(PABP) 		4 ARG A 565
GLY A 543
SER A 544
LEU A 545
 None
 1.21A 5bphD-2x04A:
undetectable		 5bphD-2x04A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yf0 MYOTUBULARIN-RELATED
PROTEIN 6

(Homo sapiens) 		PF06602
(Myotub-related) 		4 LYS A 250
GLY A 254
SER A 208
LEU A 207
 None
 1.13A 5bphD-2yf0A:
undetectable		 5bphD-2yf0A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b86 GENERAL
ODORANT-BINDING
PROTEIN LUSH

(Drosophila
melanogaster) 		PF01395
(PBP_GOBP) 		4 TYR A 107
LYS A 111
GLY A  34
LEU A  31
 None
 1.26A 5bphD-3b86A:
undetectable		 5bphD-3b86A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjq PHAGE-RELATED
PROTEIN

(Bordetella
bronchiseptica) 		PF03864
(Phage_cap_E) 		4 TYR A 136
GLY A 263
SER A 299
LEU A 298
 None
 1.21A 5bphD-3bjqA:
undetectable		 5bphD-3bjqA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bwn L-TRYPTOPHAN
AMINOTRANSFERASE

(Arabidopsis
thaliana) 		PF04864
(Alliinase_C) 		4 TYR A 199
GLY A  30
SER A 365
LEU A 367
 None
 1.30A 5bphD-3bwnA:
undetectable		 5bphD-3bwnA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmn PUTATIVE HYDROLASE

(Chloroflexus
aurantiacus) 		PF10103
(Zincin_2) 		4 TYR A 168
GLY A 180
SER A 181
LEU A 182
 None
 1.22A 5bphD-3cmnA:
undetectable		 5bphD-3cmnA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3y UNCHARACTERIZED
PROTEIN

(Enterococcus
faecalis) 		PF05193
(Peptidase_M16_C) 		4 TYR A 258
ARG A 338
SER A 331
LEU A 334
 None
 1.07A 5bphD-3d3yA:
undetectable		 5bphD-3d3yA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d5e PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE

(Homo sapiens) 		PF03403
(PAF-AH_p_II) 		4 TYR A 144
GLY A  66
SER A  87
LEU A 138
 None
 1.08A 5bphD-3d5eA:
undetectable		 5bphD-3d5eA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f08 UNCHARACTERIZED
PROTEIN Q6HG14

(Bacillus
thuringiensis) 		PF10604
(Polyketide_cyc2) 		4 ARG A  46
GLY A  23
SER A  26
LEU A  27
 None
 1.31A 5bphD-3f08A:
undetectable		 5bphD-3f08A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fmc PUTATIVE
SUCCINYLGLUTAMATE
DESUCCINYLASE /
ASPARTOACYLASE

(Shewanella
amazonensis) 		PF04952
(AstE_AspA) 		4 TYR A 289
LYS A 359
GLY A 173
SER A 176
 None
 1.30A 5bphD-3fmcA:
1.8		 5bphD-3fmcA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1l CYTOCHROME B
MITOCHONDRIAL
UBIQUINOL-CYTOCHROME
C REDUCTASE 14 KDA
PROTEIN

(Gallus gallus;
Gallus gallus) 		PF00032
(Cytochrom_B_C)
PF00033
(Cytochrome_B)
PF02271
(UCR_14kD) 		4 TYR F  20
GLY C 371
SER C 322
LEU C 321
 None
 1.17A 5bphD-3h1lF:
undetectable		 5bphD-3h1lF:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjn THYMIDYLATE KINASE

(Thermotoga
maritima) 		PF02223
(Thymidylate_kin) 		4 LYS A  45
GLY A  38
SER A  67
LEU A  70
 None
 1.25A 5bphD-3hjnA:
3.5		 5bphD-3hjnA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hnp OXIDOREDUCTASE

(Bacillus cereus) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 TYR A 155
GLY A 170
SER A 174
LEU A 175
 None
 0.83A 5bphD-3hnpA:
6.0		 5bphD-3hnpA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihm STYRENE
MONOOXYGENASE A

(Pseudomonas
putida) 		no annotation 4 ARG A 340
GLY A 280
SER A 333
LEU A 336
 None
 1.11A 5bphD-3ihmA:
2.2		 5bphD-3ihmA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ima CYSTEINE PROTEINASE
INHIBITOR

(Colocasia
esculenta) 		PF16845
(SQAPI) 		4 TYR B  71
LYS B  69
GLY B  65
LEU B  38
 None
 1.13A 5bphD-3imaB:
undetectable		 5bphD-3imaB:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k30 HISTAMINE
DEHYDROGENASE

(Pimelobacter
simplex) 		PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2) 		4 TYR A 535
GLY A 443
SER A 434
LEU A 439
 None
 1.07A 5bphD-3k30A:
7.9		 5bphD-3k30A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kew DHHA1 DOMAIN PROTEIN

(Clostridium
perfringens) 		PF01411
(tRNA-synt_2c)
PF07973
(tRNA_SAD) 		4 TYR A 157
LYS A 155
GLY A 187
LEU A 190
 None
 1.20A 5bphD-3kewA:
undetectable		 5bphD-3kewA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lwu SUCCINYLGLUTAMATE
DESUCCINYLASE/ASPART
OACYLASE

(Shewanella
frigidimarina) 		PF04952
(AstE_AspA) 		4 TYR A 291
LYS A 361
GLY A 175
SER A 178
 UNL  A 373 ( 4.4A)
UNL  A 373 ( 2.9A)
UNL  A 373 ( 3.5A)
None
 1.22A 5bphD-3lwuA:
undetectable		 5bphD-3lwuA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mcx SUSD SUPERFAMILY
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ARG A 189
GLY A 161
SER A 171
LEU A 172
 None
 1.07A 5bphD-3mcxA:
undetectable		 5bphD-3mcxA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3myv SUSD SUPERFAMILY
PROTEIN

(Bacteroides
vulgatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ARG A 183
GLY A 155
SER A 165
LEU A 166
 None
 0.96A 5bphD-3myvA:
undetectable		 5bphD-3myvA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pfd ACYL-COA
DEHYDROGENASE

(Mycolicibacterium
thermoresistibile) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 TYR A 372
GLY A 215
SER A  92
LEU A  95
 FDA  A 390 (-4.9A)
None
None
None
 0.88A 5bphD-3pfdA:
undetectable		 5bphD-3pfdA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pfo PUTATIVE
ACETYLORNITHINE
DEACETYLASE

(Rhodopseudomonas
palustris) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 TYR A 386
GLY A 183
SER A 186
LEU A 185
 None
 1.28A 5bphD-3pfoA:
undetectable		 5bphD-3pfoA:
23.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3r5x D-ALANINE--D-ALANINE
LIGASE

(Bacillus
anthracis) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ARG A 246
GLY A 266
SER A 271
LEU A 272
 None
 0.25A 5bphD-3r5xA:
15.2		 5bphD-3r5xA:
37.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3srz TOXIN A

(Clostridioides
difficile) 		PF12918
(TcdB_N)
PF12919
(TcdA_TcdB) 		4 TYR A 329
GLY A 291
SER A 508
LEU A 289
 None
 1.23A 5bphD-3srzA:
undetectable		 5bphD-3srzA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w01 HEPTAPRENYLGLYCERYL
PHOSPHATE SYNTHASE

(Staphylococcus
aureus) 		PF01884
(PcrB) 		4 TYR A 213
LYS A  17
GLY A  38
LEU A  13
 None
 1.00A 5bphD-3w01A:
undetectable		 5bphD-3w01A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bc7 ALKYLDIHYDROXYACETON
EPHOSPHATE SYNTHASE,
PEROXISOMAL

(Cavia porcellus) 		PF01565
(FAD_binding_4)
PF02913
(FAD-oxidase_C) 		4 ARG A 623
GLY A 618
SER A 242
LEU A 622
 None
 1.23A 5bphD-4bc7A:
undetectable		 5bphD-4bc7A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c7v TRANSKETOLASE

(Lactobacillus
salivarius) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 TYR A 623
GLY A 540
SER A 586
LEU A 584
 None
 1.24A 5bphD-4c7vA:
5.3		 5bphD-4c7vA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cpn NEURAMINIDASE

(Influenza B
virus) 		PF00064
(Neur) 		4 ARG A 299
GLY A 350
SER A 365
LEU A 322
 None
 1.26A 5bphD-4cpnA:
undetectable		 5bphD-4cpnA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN

(Parabacteroides
merdae) 		PF14725
(DUF4466) 		4 TYR A 231
GLY A 294
SER A 227
LEU A 226
 None
 1.07A 5bphD-4ei0A:
undetectable		 5bphD-4ei0A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eps HYPOTHETICAL PROTEIN

(Bacteroides
ovatus) 		PF13149
(Mfa_like_1) 		4 TYR A 509
GLY A 459
SER A 458
LEU A 461
 None
 1.26A 5bphD-4epsA:
undetectable		 5bphD-4epsA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ewj ENOLASE 2

(Streptococcus
suis) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		4 TYR A 408
GLY A 206
SER A 400
LEU A 399
 None
 1.28A 5bphD-4ewjA:
undetectable		 5bphD-4ewjA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gei THIOREDOXIN-INTERACT
ING PROTEIN

(Homo sapiens) 		PF00339
(Arrestin_N) 		4 TYR A 123
GLY A 108
SER A  23
LEU A 105
 None
 1.06A 5bphD-4geiA:
undetectable		 5bphD-4geiA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gtr PROTEIN
FARNESYLTRANSFERASE/
GERANYLGERANYLTRANSF
ERASE TYPE-1 SUBUNIT
ALPHA

(Rattus
norvegicus) 		PF01239
(PPTA) 		4 TYR A 292
ARG A 253
SER A 251
LEU A 256
 None
 1.29A 5bphD-4gtrA:
undetectable		 5bphD-4gtrA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gwn MEPRIN A SUBUNIT
BETA

(Homo sapiens) 		PF00629
(MAM)
PF01400
(Astacin) 		4 ARG A 293
GLY A 349
SER A 411
LEU A 412
 None
 1.06A 5bphD-4gwnA:
undetectable		 5bphD-4gwnA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igl YENB
YENC2

(Yersinia
entomophaga;
Yersinia
entomophaga) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN)
no annotation 		4 TYR A1343
GLY B 190
SER B 187
LEU B 188
 None
 1.22A 5bphD-4iglA:
undetectable		 5bphD-4iglA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jqt PUTATIVE GLYCOSYL
HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF06439
(DUF1080) 		4 TYR A  69
LYS A  67
GLY A  33
LEU A  25
 None
None
EDO  A 503 (-3.6A)
None
 1.23A 5bphD-4jqtA:
undetectable		 5bphD-4jqtA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ll1 THIOREDOXIN-INTERACT
ING PROTEIN

(Homo sapiens) 		PF00339
(Arrestin_N)
PF02752
(Arrestin_C) 		4 TYR A 123
GLY A 108
SER A  23
LEU A 105
 None
 1.18A 5bphD-4ll1A:
undetectable		 5bphD-4ll1A:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mu6 KINECTIN 1 (KINESIN
RECEPTOR)

(Legionella
pneumophila) 		no annotation 4 TYR A 270
GLY A  31
SER A  28
LEU A  27
 None
 1.28A 5bphD-4mu6A:
undetectable		 5bphD-4mu6A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mx8 PERIPLASMIC BINDING
PROTEIN

(Xylanimonas
cellulosilytica) 		PF01497
(Peripla_BP_2) 		4 TYR A  17
GLY A 110
SER A 130
LEU A 129
 None
 1.10A 5bphD-4mx8A:
3.3		 5bphD-4mx8A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nae HEPTAPRENYLGLYCERYL
PHOSPHATE SYNTHASE

(Geobacillus
kaustophilus) 		PF01884
(PcrB) 		4 TYR A 213
LYS A  17
GLY A  38
LEU A  13
 None
 1.04A 5bphD-4naeA:
undetectable		 5bphD-4naeA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o9x TCDB2, TCCC3

(Photorhabdus
luminescens) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN) 		4 TYR A1365
GLY A1700
SER A1697
LEU A1698
 None
 1.24A 5bphD-4o9xA:
undetectable		 5bphD-4o9xA:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkr TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Arthrobacter
sp. FB24) 		PF13377
(Peripla_BP_3) 		4 TYR A  84
GLY A 305
SER A  91
LEU A 301
 LBT  A 401 ( 3.7A)
None
None
None
 1.22A 5bphD-4rkrA:
4.6		 5bphD-4rkrA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tz5 PUTATIVE SECRETED
PROTEIN

(Streptomyces
sp. SirexAA-E) 		no annotation 4 TYR A 505
GLY A 576
SER A 573
LEU A 574
 BGC  A 702 (-4.6A)
None
None
BGC  A 702 ( 4.0A)
 1.02A 5bphD-4tz5A:
undetectable		 5bphD-4tz5A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zo6 LIN1840 PROTEIN

(Listeria
innocua) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 ARG A 508
GLY A 148
SER A 476
LEU A 477
 None
 1.14A 5bphD-4zo6A:
4.4		 5bphD-4zo6A:
18.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4zqi D-ALANINE--D-ALANINE
LIGASE

(Yersinia pestis) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ARG A 255
GLY A 276
SER A 281
LEU A 282
 None
 0.57A 5bphD-4zqiA:
45.8		 5bphD-4zqiA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a29 EXOPOLYGALACTURONATE
LYASE

(Vibrio
vulnificus) 		PF06917
(Pectate_lyase_2) 		4 TYR A 481
GLY A 442
SER A 443
LEU A 444
 None
None
EDO  A1580 (-4.3A)
None
 1.23A 5bphD-5a29A:
undetectable		 5bphD-5a29A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a31 ANAPHASE-PROMOTING
COMPLEX SUBUNIT 5

(Homo sapiens) 		PF12862
(ANAPC5) 		4 ARG O 298
GLY O 297
SER O 299
LEU O 283
 None
 1.26A 5bphD-5a31O:
undetectable		 5bphD-5a31O:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5amz THAUMATIN-1

(Thaumatococcus
daniellii) 		PF00314
(Thaumatin) 		4 TYR A 199
GLY A  48
SER A  91
LEU A  92
 None
 1.16A 5bphD-5amzA:
undetectable		 5bphD-5amzA:
20.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dmx D-ALANINE--D-ALANINE
LIGASE

(Acinetobacter
baumannii) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ARG A 253
GLY A 274
SER A 279
LEU A 280
 None
 0.62A 5bphD-5dmxA:
31.4		 5bphD-5dmxA:
53.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7q ACYL-COA SYNTHETASE

(Streptomyces
platensis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 TYR A 144
GLY A 151
SER A  45
LEU A  42
 None
 1.25A 5bphD-5e7qA:
4.1		 5bphD-5e7qA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f4z EPOXIDE HYDROLASE

(Streptomyces
carzinostaticus) 		PF06441
(EHN) 		4 TYR A 169
GLY A 186
SER A 185
LEU A 184
 None
 1.25A 5bphD-5f4zA:
undetectable		 5bphD-5f4zA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fca ACID
SPHINGOMYELINASE-LIK
E PHOSPHODIESTERASE
3A

(Mus musculus) 		PF00149
(Metallophos) 		4 LYS A 383
GLY A 304
SER A 300
LEU A 307
 None
 1.28A 5bphD-5fcaA:
undetectable		 5bphD-5fcaA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis) 		PF13416
(SBP_bac_8) 		4 TYR A  74
GLY A 327
SER A  92
LEU A  95
 None
 1.24A 5bphD-5gx8A:
undetectable		 5bphD-5gx8A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h2t TREHALOSE SYNTHASE

(Thermomonospora
curvata) 		no annotation 4 ARG A 372
GLY A 458
SER A 459
LEU A 460
 None
 1.30A 5bphD-5h2tA:
undetectable		 5bphD-5h2tA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hu7 PUTATIVE POLYKETIDE
SYNTHASE

(Brevibacillus
brevis) 		PF14765
(PS-DH) 		4 LYS A3111
GLY A3131
SER A3102
LEU A3114
 None
 1.10A 5bphD-5hu7A:
undetectable		 5bphD-5hu7A:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ic7 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		no annotation 4 ARG A 497
GLY A 479
SER A 427
LEU A 468
 None
 0.96A 5bphD-5ic7A:
undetectable		 5bphD-5ic7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii) 		PF00150
(Cellulase) 		4 TYR A 268
GLY A 312
SER A 311
LEU A 314
 None
 1.07A 5bphD-5ihsA:
undetectable		 5bphD-5ihsA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F

(Escherichia
coli) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF00975
(Thioesterase)
PF13193
(AMP-binding_C) 		4 TYR A 631
GLY A 776
SER A 756
LEU A 745
 None
 1.21A 5bphD-5ja1A:
3.4		 5bphD-5ja1A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l26 NUCLEOSIDE PERMEASE

(Neisseria
wadsworthii) 		PF01773
(Nucleos_tra2_N)
PF07662
(Nucleos_tra2_C)
PF07670
(Gate) 		4 TYR A 342
GLY A 321
SER A 322
LEU A 323
 None
 1.28A 5bphD-5l26A:
undetectable		 5bphD-5l26A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqp CONDENSIN COMPLEX
SUBUNIT 3

(Saccharomyces
cerevisiae) 		no annotation 4 TYR A 839
LYS A 848
SER A 889
LEU A 885
 None
 1.27A 5bphD-5oqpA:
undetectable		 5bphD-5oqpA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uxn PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE

(Pseudomonas
aeruginosa) 		no annotation 4 TYR A 387
ARG A 447
GLY A 100
LEU A 443
 None
 1.29A 5bphD-5uxnA:
undetectable		 5bphD-5uxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v1w GLYCOSIDE HYDROLASE

(Bacillus
halodurans) 		PF03639
(Glyco_hydro_81) 		4 TYR A 176
GLY A  82
SER A  83
LEU A  84
 None
 1.27A 5bphD-5v1wA:
undetectable		 5bphD-5v1wA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vob FAB 8I21 HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 TYR H 203
GLY H 143
SER H 196
LEU H 198
 None
 1.25A 5bphD-5vobH:
undetectable		 5bphD-5vobH:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wqs BETA-AMYLASE

(Ipomoea batatas) 		no annotation 4 TYR A 155
GLY A 139
SER A 137
LEU A 136
 None
 1.06A 5bphD-5wqsA:
undetectable		 5bphD-5wqsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zal ENDORIBONUCLEASE
DICER

(Homo sapiens) 		no annotation 4 TYR A1335
GLY A1341
SER A1344
LEU A1343
 None
 1.12A 5bphD-5zalA:
undetectable		 5bphD-5zalA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG

(Homo sapiens) 		no annotation 4 TYR A 275
GLY A 299
SER A 304
LEU A 301
 None
 1.19A 5bphD-6au8A:
undetectable		 5bphD-6au8A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bvg PROTEIN-N(PI)-PHOSPH
OHISTIDINE-SUGAR
PHOSPHOTRANSFERASE
(ENZYME II OF THE
PHOSPHOTRANSFERASE
SYSTEM) (PTS SYSTEM
GLUCOSE-SPECIFIC
IIBC COMPONENT)

(Bacillus cereus) 		no annotation 4 TYR A 372
GLY A 352
SER A 314
LEU A 318
 None
 1.14A 5bphD-6bvgA:
undetectable		 5bphD-6bvgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dgb IS607 FAMILY
TRANSPOSASE IS1535

(Mycobacterium
tuberculosis) 		no annotation 4 TYR A  55
ARG A 100
GLY A  95
SER A  59
 None
 1.23A 5bphD-6dgbA:
5.4		 5bphD-6dgbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1

(Homo sapiens) 		no annotation 4 LYS A 364
GLY A 342
SER A 338
LEU A 339
 None
 1.24A 5bphD-6f9nA:
undetectable		 5bphD-6f9nA:
undetectable