SIMILAR PATTERNS OF AMINO ACIDS FOR 5BPH_C_ACTC403

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
12as ASPARAGINE
SYNTHETASE

(Escherichia
coli) 		PF03590
(AsnA) 		4 TYR A 218
GLY A  50
SER A  49
LEU A  48
 ASN  A 331 (-4.3A)
None
None
None
 1.20A 5bphC-12asA:
undetectable		 5bphC-12asA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dmw PHENYLALANINE
HYDROXYLASE

(Homo sapiens) 		PF00351
(Biopterin_H) 		4 TYR A 198
GLY A 352
SER A 350
LEU A 354
 None
 1.38A 5bphC-1dmwA:
0.0		 5bphC-1dmwA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e08 CYTOCHROME C553

(Desulfovibrio
vulgaris) 		PF00034
(Cytochrom_C) 		4 TYR E   7
GLY E  33
SER E  77
LEU E  79
 HEM  E  80 ( 4.9A)
None
None
None
 1.30A 5bphC-1e08E:
undetectable		 5bphC-1e08E:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6y METHYL-COENZYME M
REDUCTASE SUBUNIT
ALPHA

(Methanosarcina
barkeri) 		PF02249
(MCR_alpha)
PF02745
(MCR_alpha_N) 		4 TYR A1498
GLY A1446
SER A1445
LEU A1444
 None
 1.46A 5bphC-1e6yA:
undetectable		 5bphC-1e6yA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8x MYOSIN II HEAVY
CHAIN FUSED TO
ALPHA-ACTININ 3

(Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		4 TYR A 705
GLY A 749
SER A  95
LEU A 751
 None
 1.32A 5bphC-1g8xA:
undetectable		 5bphC-1g8xA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h14 ENDO-1,4-BETA-XYLANA
SE

(Pseudoalteromonas
haloplanktis) 		PF01270
(Glyco_hydro_8) 		4 TYR A 329
GLY A 311
SER A 314
LEU A 313
 None
 1.35A 5bphC-1h14A:
undetectable		 5bphC-1h14A:
21.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1iov D-ALA:D-ALA LIGASE

(Escherichia
coli) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 TYR A 210
GLY A 276
SER A 281
LEU A 282
 None
POB  A 321 (-3.2A)
POB  A 321 ( 2.2A)
POB  A 321 (-3.7A)
 0.76A 5bphC-1iovA:
24.3		 5bphC-1iovA:
73.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jsd HAEMAGGLUTININ (HA1
CHAIN)

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 TYR A  78
GLY A 266
SER A 265
LEU A  41
 None
 1.22A 5bphC-1jsdA:
undetectable		 5bphC-1jsdA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1muu GDP-MANNOSE
6-DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		4 TYR A 211
GLY A  92
SER A  88
LEU A  94
 None
 0.92A 5bphC-1muuA:
4.0		 5bphC-1muuA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1phz PROTEIN
(PHENYLALANINE
HYDROXYLASE)

(Rattus
norvegicus) 		PF00351
(Biopterin_H)
PF01842
(ACT) 		4 TYR A 198
GLY A 352
SER A 350
LEU A 354
 None
 1.42A 5bphC-1phzA:
0.0		 5bphC-1phzA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pks PHOSPHATIDYLINOSITOL
3-KINASE P85-ALPHA
SUBUNIT SH3 DOMAIN

(Homo sapiens) 		PF07653
(SH3_2) 		4 TYR A   8
GLY A  35
SER A  36
LEU A  37
 None
 1.33A 5bphC-1pksA:
undetectable		 5bphC-1pksA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1taq TAQ DNA POLYMERASE

(Thermus
aquaticus) 		PF00476
(DNA_pol_A)
PF01367
(5_3_exonuc)
PF02739
(5_3_exonuc_N)
PF09281
(Taq-exonuc) 		4 TYR A  45
GLY A 279
SER A 280
LEU A 281
 None
 1.26A 5bphC-1taqA:
undetectable		 5bphC-1taqA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1us4 PUTATIVE GLUR0
LIGAND BINDING CORE

(Thermus
thermophilus) 		PF16868
(NMT1_3) 		4 TYR A 109
GLY A  26
SER A  25
LEU A  76
 None
GLU  A1313 ( 3.8A)
None
None
 1.37A 5bphC-1us4A:
2.9		 5bphC-1us4A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v0z NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 TYR A 288
GLY A 364
SER A 367
LEU A 362
 None
 1.38A 5bphC-1v0zA:
undetectable		 5bphC-1v0zA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w2w 5-METHYLTHIORIBOSE-1
-PHOSPHATE ISOMERASE
5-METHYLTHIORIBOSE-1
-PHOSPHATE ISOMERASE

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF01008
(IF-2B)
PF01008
(IF-2B) 		4 TYR B 244
GLY A 184
SER A 185
LEU A 186
 None
 1.37A 5bphC-1w2wB:
3.1		 5bphC-1w2wB:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp. KM) 		PF00480
(ROK) 		4 TYR A 198
GLY A 223
SER A 225
LEU A 149
 None
 1.23A 5bphC-1woqA:
undetectable		 5bphC-1woqA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x52 PELOTA HOMOLOG

(Homo sapiens) 		PF03465
(eRF1_3) 		4 TYR A  29
GLY A 108
SER A 104
LEU A 106
 None
 1.23A 5bphC-1x52A:
undetectable		 5bphC-1x52A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zuo HYPOTHETICAL PROTEIN
LOC92912

(Homo sapiens) 		PF00179
(UQ_con) 		4 TYR A 346
GLY A 294
SER A 293
LEU A 292
 None
 1.39A 5bphC-1zuoA:
undetectable		 5bphC-1zuoA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2amc PHENYLALANYL-TRNA
SYNTHETASE ALPHA
CHAIN
PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Thermus
thermophilus;
Thermus
thermophilus) 		PF01409
(tRNA-synt_2d)
PF01409
(tRNA-synt_2d)
PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		4 TYR B 612
GLY B 595
SER A  94
LEU A  95
 None
 1.03A 5bphC-2amcB:
undetectable		 5bphC-2amcB:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ap1 PUTATIVE REGULATOR
PROTEIN

(Salmonella
enterica) 		PF00480
(ROK) 		4 TYR A 229
GLY A 254
SER A 256
LEU A 130
 None
 1.13A 5bphC-2ap1A:
undetectable		 5bphC-2ap1A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d5r CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 7

(Homo sapiens) 		PF04857
(CAF1) 		4 TYR A  88
GLY A 228
SER A 231
LEU A 232
 None
 1.41A 5bphC-2d5rA:
undetectable		 5bphC-2d5rA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2frx HYPOTHETICAL PROTEIN
YEBU

(Escherichia
coli) 		PF01189
(Methyltr_RsmB-F)
PF13636
(Methyltranf_PUA)
PF17125
(Methyltr_RsmF_N) 		4 TYR A 464
GLY A  95
SER A  94
LEU A  93
 None
 1.44A 5bphC-2frxA:
undetectable		 5bphC-2frxA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fv0 UNSATURATED
GLUCURONYL HYDROLASE

(Bacillus sp.
GL1) 		PF07470
(Glyco_hydro_88) 		4 TYR A 356
GLY A  90
SER A  94
LEU A  95
 None
 0.95A 5bphC-2fv0A:
undetectable		 5bphC-2fv0A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2je1 ACIDIC LEUCINE-RICH
NUCLEAR
PHOSPHOPROTEIN 32
FAMILY MEMBER A

(Homo sapiens) 		PF14580
(LRR_9) 		4 TYR A 131
GLY A  97
SER A  96
LEU A 120
 None
 1.41A 5bphC-2je1A:
undetectable		 5bphC-2je1A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nx2 HYPOTHETICAL PROTEIN
YPSA

(Bacillus
subtilis) 		PF06908
(DUF1273) 		4 TYR A 164
GLY A  42
SER A   0
LEU A   1
 None
 1.18A 5bphC-2nx2A:
2.2		 5bphC-2nx2A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgx UBIQUITIN-CONJUGATIN
G ENZYME E2 Q1

(Homo sapiens) 		PF00179
(UQ_con) 		4 TYR A 146
GLY A  94
SER A  93
LEU A  92
 None
 1.44A 5bphC-2qgxA:
undetectable		 5bphC-2qgxA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qos COMPLEMENT COMPONENT
8, GAMMA POLYPEPTIDE

(Homo sapiens) 		PF00061
(Lipocalin) 		4 TYR C 161
GLY C 144
SER C 143
LEU C 142
 None
 1.32A 5bphC-2qosC:
undetectable		 5bphC-2qosC:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2toh TYROSINE
3-MONOOXYGENASE

(Rattus
norvegicus) 		PF00351
(Biopterin_H) 		4 TYR A 244
GLY A 398
SER A 396
LEU A 400
 None
 1.44A 5bphC-2tohA:
undetectable		 5bphC-2tohA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vl8 CYTOTOXIN L

(Paeniclostridium
sordellii) 		PF12918
(TcdB_N)
PF12919
(TcdA_TcdB) 		4 TYR A 330
GLY A 292
SER A 509
LEU A 290
 None
 1.20A 5bphC-2vl8A:
undetectable		 5bphC-2vl8A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vr3 CLUMPING FACTOR A

(Staphylococcus
aureus) 		PF10425
(SdrG_C_C) 		4 TYR A 394
GLY A 414
SER A 507
LEU A 505
 None
 1.39A 5bphC-2vr3A:
undetectable		 5bphC-2vr3A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ww2 ALPHA-1,2-MANNOSIDAS
E

(Bacteroides
thetaiotaomicron) 		PF07971
(Glyco_hydro_92) 		4 TYR A  75
GLY A  37
SER A 640
LEU A  35
 None
None
MPD  A 759 (-3.9A)
MPD  A 759 ( 4.0A)
 1.22A 5bphC-2ww2A:
undetectable		 5bphC-2ww2A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xr7 MALONYLTRANSFERASE

(Nicotiana
tabacum) 		PF02458
(Transferase) 		4 TYR A  26
GLY A 365
SER A 364
LEU A 363
 None
 1.46A 5bphC-2xr7A:
undetectable		 5bphC-2xr7A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3any ETHANOLAMINE
AMMONIA-LYASE LIGHT
CHAIN

(Escherichia
coli) 		PF05985
(EutC) 		4 TYR B 133
GLY B 227
SER B 170
LEU B 169
 None
None
None
B12  B 601 ( 4.4A)
 1.45A 5bphC-3anyB:
undetectable		 5bphC-3anyB:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bga BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		4 TYR A 124
GLY A 486
SER A 448
LEU A 449
 None
 1.06A 5bphC-3bgaA:
undetectable		 5bphC-3bgaA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjq PHAGE-RELATED
PROTEIN

(Bordetella
bronchiseptica) 		PF03864
(Phage_cap_E) 		4 TYR A 136
GLY A 263
SER A 299
LEU A 298
 None
 1.12A 5bphC-3bjqA:
undetectable		 5bphC-3bjqA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bwn L-TRYPTOPHAN
AMINOTRANSFERASE

(Arabidopsis
thaliana) 		PF04864
(Alliinase_C) 		4 TYR A 199
GLY A  30
SER A 365
LEU A 367
 None
 1.28A 5bphC-3bwnA:
undetectable		 5bphC-3bwnA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmn PUTATIVE HYDROLASE

(Chloroflexus
aurantiacus) 		PF10103
(Zincin_2) 		4 TYR A 168
GLY A 180
SER A 181
LEU A 182
 None
 1.23A 5bphC-3cmnA:
undetectable		 5bphC-3cmnA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dte IRRE PROTEIN

(Deinococcus
deserti) 		PF06114
(Peptidase_M78) 		4 TYR A  25
GLY A  31
SER A  36
LEU A  37
 None
 1.39A 5bphC-3dteA:
undetectable		 5bphC-3dteA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3euj CHROMOSOME PARTITION
PROTEIN MUKB, LINKER

([Haemophilus]
ducreyi) 		PF04310
(MukB)
PF13558
(SbcCD_C) 		4 TYR A1371
GLY A1362
SER A1337
LEU A1340
 None
 1.33A 5bphC-3eujA:
undetectable		 5bphC-3eujA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g5s METHYLENETETRAHYDROF
OLATE--TRNA-(URACIL-
5-)-METHYLTRANSFERAS
E TRMFO

(Thermus
thermophilus) 		PF01134
(GIDA) 		4 TYR A 103
GLY A  75
SER A  76
LEU A  77
 None
 1.46A 5bphC-3g5sA:
2.0		 5bphC-3g5sA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1l CYTOCHROME B
MITOCHONDRIAL
UBIQUINOL-CYTOCHROME
C REDUCTASE 14 KDA
PROTEIN

(Gallus gallus;
Gallus gallus) 		PF00032
(Cytochrom_B_C)
PF00033
(Cytochrome_B)
PF02271
(UCR_14kD) 		4 TYR F  20
GLY C 371
SER C 322
LEU C 321
 None
 1.19A 5bphC-3h1lF:
undetectable		 5bphC-3h1lF:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT

(Vibrio
vulnificus) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF13588
(HSDR_N_2) 		4 TYR A 374
GLY A 365
SER A 361
LEU A 362
 None
 1.42A 5bphC-3h1tA:
2.3		 5bphC-3h1tA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hnp OXIDOREDUCTASE

(Bacillus cereus) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 TYR A 155
GLY A 170
SER A 174
LEU A 175
 None
 0.89A 5bphC-3hnpA:
6.1		 5bphC-3hnpA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k30 HISTAMINE
DEHYDROGENASE

(Pimelobacter
simplex) 		PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2) 		4 TYR A 535
GLY A 443
SER A 434
LEU A 439
 None
 1.12A 5bphC-3k30A:
7.8		 5bphC-3k30A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m62 UBIQUITIN
CONJUGATION FACTOR
E4

(Saccharomyces
cerevisiae) 		PF04564
(U-box)
PF10408
(Ufd2P_core) 		4 TYR A 368
GLY A 353
SER A 352
LEU A 351
 None
 1.34A 5bphC-3m62A:
undetectable		 5bphC-3m62A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37

(Mycoplasma
genitalium) 		PF06646
(Mycoplasma_p37) 		4 TYR A 320
GLY A  61
SER A  60
LEU A  59
 None
 1.39A 5bphC-3myuA:
undetectable		 5bphC-3myuA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo sapiens) 		PF00057
(Ldl_recept_a)
PF00090
(TSP_1)
PF01823
(MACPF) 		4 TYR B 165
GLY B 119
SER B 120
LEU B 121
 None
 1.25A 5bphC-3ojyB:
undetectable		 5bphC-3ojyB:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pfo PUTATIVE
ACETYLORNITHINE
DEACETYLASE

(Rhodopseudomonas
palustris) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 TYR A 386
GLY A 183
SER A 186
LEU A 185
 None
 1.30A 5bphC-3pfoA:
3.7		 5bphC-3pfoA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rg2 ENTEROBACTIN
SYNTHASE COMPONENT E
(ENTE),
2,3-DIHYDRO-2,3-DIHY
DROXYBENZOATE
SYNTHETASE,
ISOCHROISMATASE
(ENTB)

(Escherichia
coli) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF13193
(AMP-binding_C) 		4 TYR A 207
GLY A 242
SER A 243
LEU A 244
 None
 1.39A 5bphC-3rg2A:
3.8		 5bphC-3rg2A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3srz TOXIN A

(Clostridioides
difficile) 		PF12918
(TcdB_N)
PF12919
(TcdA_TcdB) 		4 TYR A 329
GLY A 291
SER A 508
LEU A 289
 None
 1.24A 5bphC-3srzA:
undetectable		 5bphC-3srzA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tf7 42F3 MUT7 SCFV (42F3
ALPHA CHAIN, LINKER,
42F3 BETA CHAIN)

(Mus musculus) 		PF07686
(V-set) 		4 TYR C  35
GLY C  98
SER C  93
LEU C 101
 None
 1.45A 5bphC-3tf7C:
undetectable		 5bphC-3tf7C:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v4c ALDEHYDE
DEHYDROGENASE
(NADP+)

(Sinorhizobium
meliloti) 		PF00171
(Aldedh) 		4 TYR A 466
GLY A 243
SER A 240
LEU A 264
 None
 1.27A 5bphC-3v4cA:
3.6		 5bphC-3v4cA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4avc LYSINE
ACETYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF00027
(cNMP_binding)
PF13302
(Acetyltransf_3) 		4 TYR A 182
GLY A 297
SER A 275
LEU A 274
 None
 1.25A 5bphC-4avcA:
undetectable		 5bphC-4avcA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bju N-ACETYLGLUCOSAMINE-
PHOSPHATE MUTASE

(Aspergillus
fumigatus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I) 		4 TYR A 292
GLY A 210
SER A 211
LEU A 212
 None
 1.40A 5bphC-4bjuA:
undetectable		 5bphC-4bjuA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo sapiens) 		PF00995
(Sec1) 		4 TYR A 186
GLY A   8
SER A   6
LEU A  12
 None
 1.37A 5bphC-4bx9A:
undetectable		 5bphC-4bx9A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN

(Parabacteroides
merdae) 		PF14725
(DUF4466) 		4 TYR A 231
GLY A 294
SER A 227
LEU A 226
 None
 1.08A 5bphC-4ei0A:
undetectable		 5bphC-4ei0A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eps HYPOTHETICAL PROTEIN

(Bacteroides
ovatus) 		PF13149
(Mfa_like_1) 		4 TYR A 153
GLY A 274
SER A 184
LEU A 185
 GOL  A 608 ( 3.9A)
None
None
None
 1.31A 5bphC-4epsA:
undetectable		 5bphC-4epsA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eps HYPOTHETICAL PROTEIN

(Bacteroides
ovatus) 		PF13149
(Mfa_like_1) 		4 TYR A 509
GLY A 459
SER A 458
LEU A 461
 None
 1.22A 5bphC-4epsA:
undetectable		 5bphC-4epsA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gei THIOREDOXIN-INTERACT
ING PROTEIN

(Homo sapiens) 		PF00339
(Arrestin_N) 		4 TYR A 123
GLY A 108
SER A  23
LEU A 105
 None
 1.15A 5bphC-4geiA:
undetectable		 5bphC-4geiA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gmj CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 7

(Homo sapiens) 		PF04857
(CAF1) 		4 TYR B  88
GLY B 228
SER B 231
LEU B 232
 None
 1.41A 5bphC-4gmjB:
undetectable		 5bphC-4gmjB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h98 DIHYDROFOLATE
REDUCTASE

([Candida]
glabrata) 		PF00186
(DHFR_1) 		4 TYR A  35
GLY A 199
SER A 170
LEU A 173
 None
 1.08A 5bphC-4h98A:
undetectable		 5bphC-4h98A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igl YENB
YENC2

(Yersinia
entomophaga;
Yersinia
entomophaga) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN)
no annotation 		4 TYR A1343
GLY B 190
SER B 187
LEU B 188
 None
 1.25A 5bphC-4iglA:
undetectable		 5bphC-4iglA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l35 CRUXRHODOPSIN-3

(Haloarcula
vallismortis) 		PF01036
(Bac_rhodopsin) 		4 TYR A  41
GLY A 232
SER A 230
LEU A 234
 None
 1.31A 5bphC-4l35A:
undetectable		 5bphC-4l35A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lc3 PUTATIVE
UDP-4-AMINO-4-DEOXY-
L-ARABINOSE--OXOGLUT
ARATE
AMINOTRANSFERASE

(Burkholderia
cenocepacia) 		PF01041
(DegT_DnrJ_EryC1) 		4 TYR A 324
GLY A 136
SER A 135
LEU A 134
 EDO  A 403 ( 4.0A)
None
None
None
 1.40A 5bphC-4lc3A:
undetectable		 5bphC-4lc3A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mx8 PERIPLASMIC BINDING
PROTEIN

(Xylanimonas
cellulosilytica) 		PF01497
(Peripla_BP_2) 		4 TYR A  17
GLY A 110
SER A 130
LEU A 129
 None
 1.10A 5bphC-4mx8A:
4.2		 5bphC-4mx8A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o9x TCDB2, TCCC3

(Photorhabdus
luminescens) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN) 		4 TYR A1365
GLY A1700
SER A1697
LEU A1698
 None
 1.29A 5bphC-4o9xA:
undetectable		 5bphC-4o9xA:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0s CROSSOVER JUNCTION
ENDONUCLEASE MUS81

(Homo sapiens) 		PF02732
(ERCC4) 		4 TYR A 507
GLY A 533
SER A 521
LEU A 520
 None
 1.41A 5bphC-4p0sA:
undetectable		 5bphC-4p0sA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qb9 ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN

(Mycolicibacterium
smegmatis) 		PF13527
(Acetyltransf_9)
PF13530
(SCP2_2) 		4 TYR A 101
GLY A  81
SER A  83
LEU A 118
 None
None
PAR  A 500 (-4.4A)
PAR  A 500 ( 4.5A)
 1.32A 5bphC-4qb9A:
undetectable		 5bphC-4qb9A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qok MEL5 TCR CHAIN BETA

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 TYR E  36
GLY E 101
SER E  94
LEU E 103
 None
 1.41A 5bphC-4qokE:
undetectable		 5bphC-4qokE:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ri1 UDP-4-AMINO-4,6-DIDE
OXY-N-ACETYL-BETA-L-
ALTROSAMINE
N-ACETYLTRANSFERASE

(Helicobacter
pylori) 		PF13420
(Acetyltransf_4) 		4 TYR A 138
GLY A  77
SER A  78
LEU A  91
 ACO  A1301 (-4.5A)
None
None
None
 1.33A 5bphC-4ri1A:
undetectable		 5bphC-4ri1A:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkr TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Arthrobacter
sp. FB24) 		PF13377
(Peripla_BP_3) 		4 TYR A  84
GLY A 305
SER A  91
LEU A 301
 LBT  A 401 ( 3.7A)
None
None
None
 1.21A 5bphC-4rkrA:
4.7		 5bphC-4rkrA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rwy ANTIBODY 8ANC131
HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 TYR H 194
GLY H 134
SER H 187
LEU H 189
 None
 1.15A 5bphC-4rwyH:
undetectable		 5bphC-4rwyH:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tz5 PUTATIVE SECRETED
PROTEIN

(Streptomyces
sp. SirexAA-E) 		no annotation 4 TYR A 505
GLY A 575
SER A 573
LEU A 574
 BGC  A 702 (-4.6A)
None
None
BGC  A 702 ( 4.0A)
 1.30A 5bphC-4tz5A:
undetectable		 5bphC-4tz5A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tz5 PUTATIVE SECRETED
PROTEIN

(Streptomyces
sp. SirexAA-E) 		no annotation 4 TYR A 505
GLY A 576
SER A 573
LEU A 574
 BGC  A 702 (-4.6A)
None
None
BGC  A 702 ( 4.0A)
 1.07A 5bphC-4tz5A:
undetectable		 5bphC-4tz5A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v06 TRYPTOPHAN
5-HYDROXYLASE 2

(Homo sapiens) 		PF00351
(Biopterin_H) 		4 TYR A 231
GLY A 385
SER A 383
LEU A 387
 None
 1.38A 5bphC-4v06A:
undetectable		 5bphC-4v06A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wed ABC TRANSPORTER,
PERIPLASMIC
SOLUTE-BINDING
PROTEIN

(Sinorhizobium
meliloti) 		PF00496
(SBP_bac_5) 		4 TYR A 479
GLY A 431
SER A 432
LEU A 433
 None
 1.28A 5bphC-4wedA:
undetectable		 5bphC-4wedA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a29 EXOPOLYGALACTURONATE
LYASE

(Vibrio
vulnificus) 		PF06917
(Pectate_lyase_2) 		4 TYR A 481
GLY A 442
SER A 443
LEU A 444
 None
None
EDO  A1580 (-4.3A)
None
 1.26A 5bphC-5a29A:
undetectable		 5bphC-5a29A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5amz THAUMATIN-1

(Thaumatococcus
daniellii) 		PF00314
(Thaumatin) 		4 TYR A 199
GLY A  47
SER A  91
LEU A  92
 None
 1.18A 5bphC-5amzA:
undetectable		 5bphC-5amzA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5amz THAUMATIN-1

(Thaumatococcus
daniellii) 		PF00314
(Thaumatin) 		4 TYR A 199
GLY A  48
SER A  91
LEU A  92
 None
 1.20A 5bphC-5amzA:
undetectable		 5bphC-5amzA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czr CADHERIN-RELATED
FAMILY MEMBER 2

(Homo sapiens) 		PF00028
(Cadherin) 		4 TYR A 180
GLY A 169
SER A 170
LEU A 171
 None
 1.36A 5bphC-5czrA:
undetectable		 5bphC-5czrA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7g IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650

(Bacteroides
ovatus) 		no annotation 4 TYR A 313
GLY A 245
SER A 246
LEU A 287
 None
 1.38A 5bphC-5e7gA:
undetectable		 5bphC-5e7gA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650

(Bacteroides
ovatus) 		PF01833
(TIG) 		4 TYR A 313
GLY A 245
SER A 246
LEU A 287
 None
 1.38A 5bphC-5e7hA:
undetectable		 5bphC-5e7hA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7q ACYL-COA SYNTHETASE

(Streptomyces
platensis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 TYR A 144
GLY A 151
SER A  45
LEU A  42
 None
 1.30A 5bphC-5e7qA:
4.0		 5bphC-5e7qA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fgn LIPOOLIGOSACCHARIDE
PHOSPHOETHANOLAMINE
TRANSFERASE A

(Neisseria
meningitidis) 		PF00884
(Sulfatase)
PF08019
(DUF1705) 		4 TYR A 387
GLY A 475
SER A 456
LEU A 457
 None
 1.33A 5bphC-5fgnA:
undetectable		 5bphC-5fgnA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gnx BETA-GLUCOSIDASE

(metagenome) 		PF00232
(Glyco_hydro_1) 		4 TYR A 402
GLY A 439
SER A 438
LEU A 382
 None
 1.43A 5bphC-5gnxA:
undetectable		 5bphC-5gnxA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis) 		PF13416
(SBP_bac_8) 		4 TYR A  74
GLY A 327
SER A  92
LEU A  95
 None
 1.25A 5bphC-5gx8A:
undetectable		 5bphC-5gx8A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i5h INNER MEMBRANE
PROTEIN YEJM

(Escherichia
coli) 		PF00884
(Sulfatase)
PF11893
(DUF3413) 		4 TYR A 311
GLY A 320
SER A 323
LEU A 322
 None
 1.29A 5bphC-5i5hA:
undetectable		 5bphC-5i5hA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii) 		PF00150
(Cellulase) 		4 TYR A 268
GLY A 312
SER A 311
LEU A 314
 None
 0.98A 5bphC-5ihsA:
undetectable		 5bphC-5ihsA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l26 NUCLEOSIDE PERMEASE

(Neisseria
wadsworthii) 		PF01773
(Nucleos_tra2_N)
PF07662
(Nucleos_tra2_C)
PF07670
(Gate) 		4 TYR A 342
GLY A 321
SER A 322
LEU A 323
 None
 1.27A 5bphC-5l26A:
undetectable		 5bphC-5l26A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nri D-ALANINE--D-ALANINE
LIGASE

(Burkholderia
pseudomallei) 		no annotation 4 TYR A 215
GLY A 281
SER A 286
LEU A 287
 None
DAL  A 402 (-4.3A)
DAL  A 402 (-3.6A)
DAL  A 402 (-3.8A)
 0.76A 5bphC-5nriA:
39.9		 5bphC-5nriA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1

(Glycine max) 		no annotation 4 TYR A 317
GLY A 258
SER A 261
LEU A 262
 None
 1.11A 5bphC-5tr0A:
undetectable		 5bphC-5tr0A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v1w GLYCOSIDE HYDROLASE

(Bacillus
halodurans) 		PF03639
(Glyco_hydro_81) 		4 TYR A 176
GLY A  82
SER A  83
LEU A  84
 None
 1.20A 5bphC-5v1wA:
undetectable		 5bphC-5v1wA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vob FAB 8I21 HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 TYR H 203
GLY H 143
SER H 196
LEU H 198
 None
 1.25A 5bphC-5vobH:
undetectable		 5bphC-5vobH:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wk1 MAJOR CAPSID PROTEIN

(Pseudoalteromonas
phage TW1) 		no annotation 4 TYR A 350
GLY A 291
SER A 248
LEU A 289
 None
 1.41A 5bphC-5wk1A:
undetectable		 5bphC-5wk1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wqs BETA-AMYLASE

(Ipomoea batatas) 		no annotation 4 TYR A 155
GLY A 139
SER A 137
LEU A 136
 None
 1.12A 5bphC-5wqsA:
undetectable		 5bphC-5wqsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsy SODIUM CHANNEL
PROTEIN

(Electrophorus
electricus) 		PF00520
(Ion_trans)
PF06512
(Na_trans_assoc) 		4 TYR A1243
GLY A1202
SER A1205
LEU A1206
 None
 1.25A 5bphC-5xsyA:
undetectable		 5bphC-5xsyA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yk7 MAINTENANCE OF
MITOCHONDRIAL
MORPHOLOGY PROTEIN 1

(Zygosaccharomyces
rouxii) 		no annotation 4 TYR A 261
GLY A 401
SER A 402
LEU A 403
 None
 1.45A 5bphC-5yk7A:
undetectable		 5bphC-5yk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yt4 GALECTIN-10

(Homo sapiens) 		no annotation 4 TYR A 100
GLY A  17
SER A  15
LEU A  14
 None
 1.44A 5bphC-5yt4A:
undetectable		 5bphC-5yt4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zal ENDORIBONUCLEASE
DICER

(Homo sapiens) 		no annotation 4 TYR A1335
GLY A1341
SER A1344
LEU A1343
 None
 1.02A 5bphC-5zalA:
undetectable		 5bphC-5zalA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6brs PUTATIVE ZINC
PROTEASE

(Pectobacterium
atrosepticum) 		no annotation 4 TYR A 700
GLY A 506
SER A 525
LEU A 524
 None
 1.25A 5bphC-6brsA:
undetectable		 5bphC-6brsA:
undetectable