SIMILAR PATTERNS OF AMINO ACIDS FOR 5BPH_B_ACTB404

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)

(Bacillus
subtilis) 		PF00135
(COesterase) 		4 TYR A 136
GLY A 191
SER A 194
LEU A 198
 None
 1.14A 5bphB-1c7jA:
undetectable		 5bphB-1c7jA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h0h FORMATE
DEHYDROGENASE
SUBUNIT ALPHA

(Desulfovibrio
gigas) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 TYR A 812
ARG A 331
GLY A 282
SER A 825
 None
 1.08A 5bphB-1h0hA:
undetectable		 5bphB-1h0hA:
15.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1iov D-ALA:D-ALA LIGASE

(Escherichia
coli) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		7 TYR A 210
LYS A 215
TYR A 216
ARG A 255
GLY A 276
SER A 281
LEU A 282
 None
POB  A 321 (-2.5A)
None
POB  A 321 (-3.2A)
POB  A 321 (-3.2A)
POB  A 321 ( 2.2A)
POB  A 321 (-3.7A)
 0.79A 5bphB-1iovA:
18.3		 5bphB-1iovA:
73.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jbi COCHLIN

(Homo sapiens) 		PF03815
(LCCL) 		4 TYR A  75
GLY A  71
SER A  94
LEU A  69
 None
 1.05A 5bphB-1jbiA:
undetectable		 5bphB-1jbiA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k1x 4-ALPHA-GLUCANOTRANS
FERASE

(Thermococcus
litoralis) 		PF03065
(Glyco_hydro_57)
PF09094
(DUF1925)
PF09095
(DUF1926) 		4 TYR A 560
TYR A 518
SER A 419
LEU A 488
 None
 1.12A 5bphB-1k1xA:
undetectable		 5bphB-1k1xA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kya LACCASE

(Trametes
versicolor) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 TYR A 209
ARG A 121
SER A 202
LEU A 203
 None
 1.07A 5bphB-1kyaA:
undetectable		 5bphB-1kyaA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l2q MONOMETHYLAMINE
METHYLTRANSFERASE

(Methanosarcina
barkeri) 		PF05369
(MtmB) 		4 TYR A 429
GLY A 380
SER A 146
LEU A 149
 None
 1.10A 5bphB-1l2qA:
undetectable		 5bphB-1l2qA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhz METHANE
MONOOXYGENASE
HYDROXYLASE

(Methylosinus
trichosporium) 		PF02332
(Phenol_Hydrox) 		4 TYR D 137
GLY D 250
SER D 201
LEU D 204
 None
 1.05A 5bphB-1mhzD:
undetectable		 5bphB-1mhzD:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mty METHANE
MONOOXYGENASE
HYDROXYLASE

(Methylococcus
capsulatus) 		PF02332
(Phenol_Hydrox) 		4 TYR D 137
GLY D 250
SER D 201
LEU D 204
 None
 1.05A 5bphB-1mtyD:
undetectable		 5bphB-1mtyD:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1muu GDP-MANNOSE
6-DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		4 TYR A 211
GLY A  92
SER A  88
LEU A  94
 None
 0.92A 5bphB-1muuA:
4.3		 5bphB-1muuA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qwk ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1

(Caenorhabditis
elegans) 		PF00248
(Aldo_ket_red) 		4 TYR A 111
GLY A  95
SER A  99
LEU A 100
 None
 1.02A 5bphB-1qwkA:
undetectable		 5bphB-1qwkA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t6t PUTATIVE PROTEIN

(Aquifex
aeolicus) 		PF01751
(Toprim) 		4 TYR 1  51
GLY 1  48
SER 1  47
LEU 1  46
 None
 1.21A 5bphB-1t6t1:
4.0		 5bphB-1t6t1:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1to0 HYPOTHETICAL UPF0247
PROTEIN YYDA

(Bacillus
subtilis) 		PF02590
(SPOUT_MTase) 		4 LYS A  83
GLY A  80
SER A 126
LEU A 125
 None
 1.15A 5bphB-1to0A:
undetectable		 5bphB-1to0A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uky URIDYLATE KINASE

(Saccharomyces
cerevisiae) 		PF00406
(ADK) 		4 LYS A  29
ARG A 107
GLY A  48
SER A  46
 ADP  A 205 ( 2.7A)
ADP  A 206 (-3.3A)
ADP  A 206 ( 3.7A)
ADP  A 206 ( 4.6A)
 1.21A 5bphB-1ukyA:
2.9		 5bphB-1ukyA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5c CHITOSANASE

(Bacillus sp.
(in: Bacteria)) 		PF01270
(Glyco_hydro_8) 		4 TYR A 276
GLY A 288
SER A 284
LEU A 367
 None
 1.12A 5bphB-1v5cA:
undetectable		 5bphB-1v5cA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vs0 PUTATIVE DNA
LIGASE-LIKE PROTEIN
RV0938/MT0965

(Mycobacterium
tuberculosis) 		PF01068
(DNA_ligase_A_M)
PF04679
(DNA_ligase_A_C) 		4 TYR A 574
LYS A 618
GLY A 480
LEU A 595
 None
APK  A 481 ( 2.9A)
APK  A 481 ( 2.5A)
None
 0.86A 5bphB-1vs0A:
undetectable		 5bphB-1vs0A:
25.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w99 PESTICIDIAL CRYSTAL
PROTEIN CRY4BA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 LYS A 380
TYR A 379
GLY A 403
LEU A 405
 None
 1.09A 5bphB-1w99A:
undetectable		 5bphB-1w99A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT

(Homo sapiens) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 TYR A 694
GLY A 627
SER A 630
LEU A 632
 None
 1.01A 5bphB-1z68A:
2.4		 5bphB-1z68A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zak ADENYLATE KINASE

(Zea mays) 		PF00406
(ADK) 		4 LYS A  18
ARG A  94
GLY A  37
SER A  35
 AP5  A 223 (-2.7A)
AP5  A 223 (-2.9A)
AP5  A 223 (-3.6A)
None
 1.03A 5bphB-1zakA:
2.1		 5bphB-1zakA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zch HYPOTHETICAL
OXIDOREDUCTASE YCND

(Bacillus
subtilis) 		PF00881
(Nitroreductase) 		4 ARG A 139
GLY A 136
SER A 159
LEU A 158
 None
FMN  A 301 (-3.5A)
FMN  A 301 ( 3.9A)
None
 0.96A 5bphB-1zchA:
undetectable		 5bphB-1zchA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2amc PHENYLALANYL-TRNA
SYNTHETASE ALPHA
CHAIN
PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Thermus
thermophilus;
Thermus
thermophilus) 		PF01409
(tRNA-synt_2d)
PF01409
(tRNA-synt_2d)
PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		4 TYR B 612
GLY B 595
SER A  94
LEU A  95
 None
 1.06A 5bphB-2amcB:
undetectable		 5bphB-2amcB:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ap1 PUTATIVE REGULATOR
PROTEIN

(Salmonella
enterica) 		PF00480
(ROK) 		4 TYR A 229
GLY A 254
SER A 256
LEU A 130
 None
 1.17A 5bphB-2ap1A:
undetectable		 5bphB-2ap1A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c0k HEMOGLOBIN

(Gasterophilus
intestinalis) 		PF00042
(Globin) 		4 LYS A   1
GLY A  82
SER A  78
LEU A  77
 None
 1.03A 5bphB-2c0kA:
undetectable		 5bphB-2c0kA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dgk GLUTAMATE
DECARBOXYLASE BETA

(Escherichia
coli) 		PF00282
(Pyridoxal_deC) 		4 TYR A 347
GLY A 210
SER A 246
LEU A 250
 None
 1.16A 5bphB-2dgkA:
undetectable		 5bphB-2dgkA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2etv IRON(III) ABC
TRANSPORTER,
PERIPLASMIC
IRON-BINDING
PROTEIN, PUTATIVE

(Thermotoga
maritima) 		PF01497
(Peripla_BP_2) 		4 TYR A 116
GLY A 139
SER A 137
LEU A 149
 EDO  A  21 ( 4.0A)
None
None
None
 1.19A 5bphB-2etvA:
2.4		 5bphB-2etvA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fep CATABOLITE CONTROL
PROTEIN A

(Bacillus
subtilis) 		PF13377
(Peripla_BP_3) 		4 TYR A 222
TYR A  76
GLY A 125
SER A 148
 SO4  A4397 (-4.2A)
SO4  A4397 (-4.5A)
None
None
 1.05A 5bphB-2fepA:
6.3		 5bphB-2fepA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fv0 UNSATURATED
GLUCURONYL HYDROLASE

(Bacillus sp.
GL1) 		PF07470
(Glyco_hydro_88) 		4 TYR A 356
GLY A  90
SER A  94
LEU A  95
 None
 1.04A 5bphB-2fv0A:
undetectable		 5bphB-2fv0A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ix8 ELONGATION FACTOR 3A

(Saccharomyces
cerevisiae) 		PF00005
(ABC_tran) 		4 LYS A1903
GLY A1467
SER A1897
LEU A1896
 None
 1.11A 5bphB-2ix8A:
undetectable		 5bphB-2ix8A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lm4 SUCCINATE
DEHYDROGENASE
ASSEMBLY FACTOR 2,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF03937
(Sdh5) 		4 TYR A  61
GLY A  44
SER A  43
LEU A  42
 None
 1.11A 5bphB-2lm4A:
undetectable		 5bphB-2lm4A:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 ARG A 918
GLY A1036
SER A1033
LEU A1034
 None
 1.07A 5bphB-2p4iA:
undetectable		 5bphB-2p4iA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qf5 CELL SHAPE
DETERMINING PROTEIN
MREC

(Streptococcus
pneumoniae) 		PF04085
(MreC) 		4 LYS A 181
TYR A 190
GLY A 224
SER A 179
 None
 1.04A 5bphB-2qf5A:
undetectable		 5bphB-2qf5A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qt6 LACCASE

(Lentinus
tigrinus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 TYR A 209
ARG A 121
SER A 202
LEU A 203
 None
 1.02A 5bphB-2qt6A:
undetectable		 5bphB-2qt6A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR

(Bacteroides
fragilis) 		PF05406
(WGR) 		4 TYR A  83
LYS A  81
SER A 108
LEU A 106
 None
 0.96A 5bphB-2ra8A:
undetectable		 5bphB-2ra8A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2weu TRYPTOPHAN
5-HALOGENASE

(Streptomyces
rugosporus) 		PF04820
(Trp_halogenase) 		4 TYR A 166
TYR A 506
GLY A 141
LEU A 143
 None
 1.18A 5bphB-2weuA:
undetectable		 5bphB-2weuA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wsu PUTATIVE FIBER
PROTEIN

(Porcine
mastadenovirus
B) 		PF00337
(Gal-bind_lectin) 		4 ARG A 453
GLY A 455
SER A 431
LEU A 432
 None
 1.10A 5bphB-2wsuA:
undetectable		 5bphB-2wsuA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA

(Homo sapiens) 		PF04321
(RmlD_sub_bind) 		4 TYR A 186
GLY A 314
SER A 318
LEU A 319
 None
 1.18A 5bphB-2ydyA:
4.3		 5bphB-2ydyA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yf0 MYOTUBULARIN-RELATED
PROTEIN 6

(Homo sapiens) 		PF06602
(Myotub-related) 		4 LYS A 250
GLY A 254
SER A 208
LEU A 207
 None
 0.96A 5bphB-2yf0A:
undetectable		 5bphB-2yf0A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z8z LIPASE

(Pseudomonas sp.
MIS38) 		PF00353
(HemolysinCabind) 		4 TYR A 331
LYS A   2
GLY A  10
SER A  14
 None
 1.21A 5bphB-2z8zA:
undetectable		 5bphB-2z8zA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a14 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE

(Thermotoga
maritima) 		PF02670
(DXP_reductoisom)
PF08436
(DXP_redisom_C)
PF13288
(DXPR_C) 		4 LYS A 289
TYR A 290
GLY A 166
LEU A 168
 None
None
MPD  A 800 ( 4.8A)
None
 1.12A 5bphB-3a14A:
5.7		 5bphB-3a14A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bpk NITRILOTRIACETATE
MONOOXYGENASE
COMPONENT B

(Bacillus cereus) 		PF01613
(Flavin_Reduct) 		4 TYR A  46
TYR A  15
ARG A 184
GLY A 187
 None
 1.21A 5bphB-3bpkA:
undetectable		 5bphB-3bpkA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bv6 METAL-DEPENDENT
HYDROLASE

(Vibrio cholerae) 		PF13483
(Lactamase_B_3) 		4 TYR A 234
GLY A 226
SER A 249
LEU A 248
 None
 1.08A 5bphB-3bv6A:
undetectable		 5bphB-3bv6A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3y UNCHARACTERIZED
PROTEIN

(Enterococcus
faecalis) 		PF05193
(Peptidase_M16_C) 		4 TYR A 258
ARG A 338
SER A 331
LEU A 334
 None
 1.10A 5bphB-3d3yA:
undetectable		 5bphB-3d3yA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fmc PUTATIVE
SUCCINYLGLUTAMATE
DESUCCINYLASE /
ASPARTOACYLASE

(Shewanella
amazonensis) 		PF04952
(AstE_AspA) 		4 TYR A 289
LYS A 359
GLY A 173
SER A 176
 None
 1.17A 5bphB-3fmcA:
2.1		 5bphB-3fmcA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1l CYTOCHROME B
MITOCHONDRIAL
UBIQUINOL-CYTOCHROME
C REDUCTASE 14 KDA
PROTEIN

(Gallus gallus;
Gallus gallus) 		PF00032
(Cytochrom_B_C)
PF00033
(Cytochrome_B)
PF02271
(UCR_14kD) 		4 TYR F  20
GLY C 371
SER C 322
LEU C 321
 None
 1.07A 5bphB-3h1lF:
undetectable		 5bphB-3h1lF:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hnp OXIDOREDUCTASE

(Bacillus cereus) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 TYR A 155
GLY A 170
SER A 174
LEU A 175
 None
 0.84A 5bphB-3hnpA:
6.3		 5bphB-3hnpA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihm STYRENE
MONOOXYGENASE A

(Pseudomonas
putida) 		no annotation 4 ARG A 340
GLY A 280
SER A 333
LEU A 336
 None
 1.05A 5bphB-3ihmA:
undetectable		 5bphB-3ihmA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kew DHHA1 DOMAIN PROTEIN

(Clostridium
perfringens) 		PF01411
(tRNA-synt_2c)
PF07973
(tRNA_SAD) 		4 TYR A 157
LYS A 155
GLY A 187
LEU A 190
 None
 1.13A 5bphB-3kewA:
undetectable		 5bphB-3kewA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lwu SUCCINYLGLUTAMATE
DESUCCINYLASE/ASPART
OACYLASE

(Shewanella
frigidimarina) 		PF04952
(AstE_AspA) 		4 TYR A 291
LYS A 361
GLY A 175
SER A 178
 UNL  A 373 ( 4.4A)
UNL  A 373 ( 2.9A)
UNL  A 373 ( 3.5A)
None
 1.14A 5bphB-3lwuA:
undetectable		 5bphB-3lwuA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mcx SUSD SUPERFAMILY
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ARG A 189
GLY A 161
SER A 171
LEU A 172
 None
 1.03A 5bphB-3mcxA:
undetectable		 5bphB-3mcxA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ml0 PENICILLIN G
ACYLASE, BETA
SUBUNIT

(Alcaligenes
faecalis) 		PF01804
(Penicil_amidase) 		4 TYR B 351
GLY B 371
SER B 386
LEU B 385
 None
 1.15A 5bphB-3ml0B:
undetectable		 5bphB-3ml0B:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3myv SUSD SUPERFAMILY
PROTEIN

(Bacteroides
vulgatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ARG A 183
GLY A 155
SER A 165
LEU A 166
 None
 0.95A 5bphB-3myvA:
undetectable		 5bphB-3myvA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nzq BIOSYNTHETIC
ARGININE
DECARBOXYLASE

(Escherichia
coli) 		PF02784
(Orn_Arg_deC_N) 		4 TYR A 120
TYR A 335
GLY A 311
LEU A 122
 None
None
SO4  A 701 ( 3.8A)
None
 1.16A 5bphB-3nzqA:
undetectable		 5bphB-3nzqA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nzq BIOSYNTHETIC
ARGININE
DECARBOXYLASE

(Escherichia
coli) 		PF02784
(Orn_Arg_deC_N) 		4 TYR A 120
TYR A 335
GLY A 311
SER A 361
 None
None
SO4  A 701 ( 3.8A)
None
 0.99A 5bphB-3nzqA:
undetectable		 5bphB-3nzqA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pfd ACYL-COA
DEHYDROGENASE

(Mycolicibacterium
thermoresistibile) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 TYR A 372
GLY A 215
SER A  92
LEU A  95
 FDA  A 390 (-4.9A)
None
None
None
 0.96A 5bphB-3pfdA:
undetectable		 5bphB-3pfdA:
24.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3r5x D-ALANINE--D-ALANINE
LIGASE

(Bacillus
anthracis) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ARG A 246
GLY A 266
SER A 271
LEU A 272
 None
 0.27A 5bphB-3r5xA:
32.9		 5bphB-3r5xA:
37.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s9v ABIETADIENE
SYNTHASE,
CHLOROPLASTIC

(Abies grandis) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 TYR A 140
TYR A 287
GLY A 532
SER A 232
 None
 1.20A 5bphB-3s9vA:
undetectable		 5bphB-3s9vA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqg METHYL COENZYME M
REDUCTASE, ALPHA
SUBUNIT

(uncultured
archaeon) 		PF02249
(MCR_alpha)
PF02745
(MCR_alpha_N) 		4 TYR A 507
TYR A 494
GLY A 475
LEU A 443
 None
 1.21A 5bphB-3sqgA:
undetectable		 5bphB-3sqgA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos taurus) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 TYR C1213
GLY C 664
SER C 906
LEU C 905
 None
 1.06A 5bphB-3sr6C:
undetectable		 5bphB-3sr6C:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3usz EXO-1,3/1,4-BETA-GLU
CANASE

(Pseudoalteromonas
sp. BB1) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C) 		4 LYS A 585
TYR A 586
SER A 621
LEU A 620
 None
 0.86A 5bphB-3uszA:
3.9		 5bphB-3uszA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w5f BETA-GALACTOSIDASE

(Solanum
lycopersicum) 		PF01301
(Glyco_hydro_35) 		4 TYR A 470
GLY A 558
SER A 540
LEU A 500
 None
 1.04A 5bphB-3w5fA:
undetectable		 5bphB-3w5fA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1b LACCASE

(Lentinus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 TYR A 230
ARG A 142
SER A 223
LEU A 224
 None
 1.05A 5bphB-3x1bA:
undetectable		 5bphB-3x1bA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zla NUCLEOPROTEIN

(Bunyamwera
orthobunyavirus) 		PF00952
(Bunya_nucleocap) 		4 TYR A  43
GLY A  97
SER A  96
LEU A  95
 None
 1.13A 5bphB-3zlaA:
undetectable		 5bphB-3zlaA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zxs CRYPTOCHROME B

(Rhodobacter
sphaeroides) 		PF04244
(DPRP) 		4 TYR A 387
GLY A 370
SER A 407
LEU A 366
 FAD  A1509 (-3.5A)
None
FAD  A1509 ( 4.4A)
FAD  A1509 ( 4.2A)
 1.14A 5bphB-3zxsA:
2.6		 5bphB-3zxsA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cw5 DFNA

(Bacillus
velezensis) 		PF03060
(NMO) 		4 TYR A 700
GLY A 692
SER A 571
LEU A 690
 None
 1.12A 5bphB-4cw5A:
undetectable		 5bphB-4cw5A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e6s ZINC FINGER AND SCAN
DOMAIN-CONTAINING
PROTEIN 10

(Mus musculus) 		PF02023
(SCAN) 		4 TYR A  17
GLY A  22
SER A  26
LEU A  27
 None
 1.03A 5bphB-4e6sA:
undetectable		 5bphB-4e6sA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN

(Parabacteroides
merdae) 		PF14725
(DUF4466) 		4 TYR A 231
GLY A 294
SER A 227
LEU A 226
 None
 1.01A 5bphB-4ei0A:
undetectable		 5bphB-4ei0A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4epz TRANSCRIPTION
ANTI-TERMINATOR
ANTAGONIST UPXZ

(Bacteroides
uniformis) 		PF06603
(UpxZ) 		4 LYS A  79
GLY A  68
SER A  44
LEU A  41
 None
 1.06A 5bphB-4epzA:
undetectable		 5bphB-4epzA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eqv INVERTASE 2

(Saccharomyces
cerevisiae) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 TYR A 468
TYR A 266
SER A 307
LEU A 308
 None
 1.05A 5bphB-4eqvA:
undetectable		 5bphB-4eqvA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gei THIOREDOXIN-INTERACT
ING PROTEIN

(Homo sapiens) 		PF00339
(Arrestin_N) 		4 TYR A 123
GLY A 108
SER A  23
LEU A 105
 None
 1.07A 5bphB-4geiA:
undetectable		 5bphB-4geiA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gwn MEPRIN A SUBUNIT
BETA

(Homo sapiens) 		PF00629
(MAM)
PF01400
(Astacin) 		4 ARG A 293
GLY A 349
SER A 411
LEU A 412
 None
 1.10A 5bphB-4gwnA:
undetectable		 5bphB-4gwnA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h98 DIHYDROFOLATE
REDUCTASE

([Candida]
glabrata) 		PF00186
(DHFR_1) 		4 TYR A  35
GLY A 199
SER A 170
LEU A 173
 None
 1.12A 5bphB-4h98A:
undetectable		 5bphB-4h98A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hoz SUCROSE ISOMERASE

(Erwinia
rhapontici) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		4 TYR A  81
TYR A  54
SER A 409
LEU A 411
 None
 1.17A 5bphB-4hozA:
undetectable		 5bphB-4hozA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH

(Vibrio
parahaemolyticus) 		PF02386
(TrkH) 		4 TYR A 130
GLY A  84
SER A 105
LEU A 109
 None
 1.16A 5bphB-4j9uA:
undetectable		 5bphB-4j9uA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ll1 THIOREDOXIN-INTERACT
ING PROTEIN

(Homo sapiens) 		PF00339
(Arrestin_N)
PF02752
(Arrestin_C) 		4 TYR A 123
GLY A 108
SER A  23
LEU A 105
 None
 1.19A 5bphB-4ll1A:
undetectable		 5bphB-4ll1A:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mx8 PERIPLASMIC BINDING
PROTEIN

(Xylanimonas
cellulosilytica) 		PF01497
(Peripla_BP_2) 		4 TYR A  17
GLY A 110
SER A 130
LEU A 129
 None
 1.16A 5bphB-4mx8A:
3.8		 5bphB-4mx8A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4paf TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE

(Ruegeria
pomeroyi) 		PF03480
(DctP) 		4 LYS A  27
GLY A  58
SER A  53
LEU A  52
 None
 1.14A 5bphB-4pafA:
undetectable		 5bphB-4pafA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r4z PNGF-II

(Elizabethkingia
meningoseptica) 		PF09112
(N-glycanase_N)
PF09113
(N-glycanase_C) 		4 TYR A   8
GLY A 123
SER A  25
LEU A  34
 None
 1.10A 5bphB-4r4zA:
undetectable		 5bphB-4r4zA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tps SPORULATION
INHIBITOR OF
REPLICATION PROTEIN
SIRA
CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA

(Bacillus
subtilis;
Bacillus
subtilis) 		PF10747
(SirA)
PF11638
(DnaA_N) 		4 TYR B  58
TYR A  51
SER B  20
LEU B  19
 None
 1.15A 5bphB-4tpsB:
undetectable		 5bphB-4tpsB:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tz5 PUTATIVE SECRETED
PROTEIN

(Streptomyces
sp. SirexAA-E) 		no annotation 4 TYR A 505
GLY A 576
SER A 573
LEU A 574
 BGC  A 702 (-4.6A)
None
None
BGC  A 702 ( 4.0A)
 1.04A 5bphB-4tz5A:
undetectable		 5bphB-4tz5A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zo6 LIN1840 PROTEIN

(Listeria
innocua) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 ARG A 508
GLY A 148
SER A 476
LEU A 477
 None
 1.11A 5bphB-4zo6A:
4.5		 5bphB-4zo6A:
18.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4zqi D-ALANINE--D-ALANINE
LIGASE

(Yersinia pestis) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ARG A 255
GLY A 276
SER A 281
LEU A 282
 None
 0.63A 5bphB-4zqiA:
45.6		 5bphB-4zqiA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a29 EXOPOLYGALACTURONATE
LYASE

(Vibrio
vulnificus) 		PF06917
(Pectate_lyase_2) 		4 TYR A 481
GLY A 442
SER A 443
LEU A 444
 None
None
EDO  A1580 (-4.3A)
None
 1.21A 5bphB-5a29A:
undetectable		 5bphB-5a29A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5amz THAUMATIN-1

(Thaumatococcus
daniellii) 		PF00314
(Thaumatin) 		4 TYR A 199
GLY A  48
SER A  91
LEU A  92
 None
 1.13A 5bphB-5amzA:
undetectable		 5bphB-5amzA:
20.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dmx D-ALANINE--D-ALANINE
LIGASE

(Acinetobacter
baumannii) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ARG A 253
GLY A 274
SER A 279
LEU A 280
 None
 0.71A 5bphB-5dmxA:
31.3		 5bphB-5dmxA:
53.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ec3 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE

(Homo sapiens) 		PF00903
(Glyoxalase)
PF13669
(Glyoxalase_4) 		4 TYR A 295
GLY A 362
SER A 366
LEU A 367
 TYR  A 295 ( 1.3A)
GLY  A 362 ( 0.0A)
SER  A 366 ( 0.0A)
LEU  A 367 ( 0.6A)
 1.10A 5bphB-5ec3A:
undetectable		 5bphB-5ec3A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5grn PLATELET-DERIVED
GROWTH FACTOR
RECEPTOR ALPHA

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 ARG A 690
GLY A 893
SER A 890
LEU A 891
 None
 1.15A 5bphB-5grnA:
undetectable		 5bphB-5grnA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ic7 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		no annotation 4 ARG A 497
GLY A 479
SER A 427
LEU A 468
 None
 0.97A 5bphB-5ic7A:
undetectable		 5bphB-5ic7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii) 		PF00150
(Cellulase) 		4 TYR A 268
GLY A 312
SER A 311
LEU A 314
 None
 1.11A 5bphB-5ihsA:
undetectable		 5bphB-5ihsA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5inf CARBOXYL TRANSFERASE

(Streptomyces
ambofaciens) 		PF01039
(Carboxyl_trans) 		4 TYR A 380
GLY A 395
SER A 354
LEU A 398
 None
 1.00A 5bphB-5infA:
undetectable		 5bphB-5infA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lw7 ABC TRANSPORTER
ATP-BINDING PROTEIN

(Pyrococcus
abyssi) 		PF00005
(ABC_tran)
PF00037
(Fer4)
PF04068
(RLI) 		4 TYR B 170
GLY B 461
SER B 459
LEU B 463
 None
 1.18A 5bphB-5lw7B:
undetectable		 5bphB-5lw7B:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m99 ALPHA-AMYLASE

(Thermotoga
petrophila) 		PF00128
(Alpha-amylase) 		4 TYR B  60
TYR B  33
GLY B 352
LEU B 430
 EDO  B 609 (-4.9A)
None
None
None
 1.12A 5bphB-5m99B:
undetectable		 5bphB-5m99B:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nri D-ALANINE--D-ALANINE
LIGASE

(Burkholderia
pseudomallei) 		no annotation 4 TYR A 215
LYS A 220
TYR A 221
ARG A 260
 None
AMP  A 401 ( 4.2A)
None
DAL  A 402 (-4.1A)
 0.96A 5bphB-5nriA:
39.9		 5bphB-5nriA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wk1 CAPSID STABILIZING
PROTEIN

(Pseudoalteromonas
phage TW1) 		no annotation 4 LYS X  29
GLY X 140
SER X  94
LEU X 142
 None
 1.15A 5bphB-5wk1X:
undetectable		 5bphB-5wk1X:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wqs BETA-AMYLASE

(Ipomoea batatas) 		no annotation 4 TYR A 155
GLY A 139
SER A 137
LEU A 136
 None
 1.07A 5bphB-5wqsA:
undetectable		 5bphB-5wqsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xag TUBULIN TYROSINE
LIGASE

(Gallus gallus) 		no annotation 4 TYR F  14
TYR F  64
GLY F 334
LEU F 314
 None
 1.20A 5bphB-5xagF:
12.7		 5bphB-5xagF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ar3 GSI-IIC RT

(Geobacillus
stearothermophilus) 		no annotation 4 TYR A 325
GLY A 271
SER A 288
LEU A 284
 None
 1.10A 5bphB-6ar3A:
undetectable		 5bphB-6ar3A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG

(Homo sapiens) 		no annotation 4 TYR A 275
GLY A 299
SER A 304
LEU A 301
 None
 1.21A 5bphB-6au8A:
undetectable		 5bphB-6au8A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b0k IOTA-CARRAGEENAN
SULFATASE

(Pseudoalteromonas) 		no annotation 4 TYR A 229
GLY A 267
SER A 206
LEU A 271
 None
 1.01A 5bphB-6b0kA:
undetectable		 5bphB-6b0kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bf6 INSULIN-DEGRADING
ENZYME

(Homo sapiens) 		no annotation 4 TYR A 149
TYR A 249
GLY A  95
SER A 107
 None
 1.20A 5bphB-6bf6A:
undetectable		 5bphB-6bf6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fah CAFFEYL-COA
REDUCTASE-ETF
COMPLEX SUBUNIT CARE
CAFFEYL-COA
REDUCTASE-ETF
COMPLEX SUBUNIT CARD

(Acetobacterium
woodii;
Acetobacterium
woodii) 		no annotation
no annotation 		4 TYR A 374
GLY B 250
SER B 254
LEU B 256
 None
 1.19A 5bphB-6fahA:
3.8		 5bphB-6fahA:
undetectable