SIMILAR PATTERNS OF AMINO ACIDS FOR 5BPH_A_ACTA403

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
12as ASPARAGINE
SYNTHETASE

(Escherichia
coli) 		PF03590
(AsnA) 		4 TYR A 218
GLY A  50
SER A  49
LEU A  48
 ASN  A 331 (-4.3A)
None
None
None
 1.19A 5bphA-12asA:
undetectable		 5bphA-12asA:
24.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ehi D-ALANINE:D-LACTATE
LIGASE

(Leuconostoc
mesenteroides) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 TYR A 255
LYS A 260
GLY A 322
SER A 327
 None
PHY  A 782 ( 2.6A)
PHY  A 782 (-3.5A)
PHY  A 782 (-2.6A)
 0.77A 5bphA-1ehiA:
36.2		 5bphA-1ehiA:
31.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus) 		PF03572
(Peptidase_S41)
PF13180
(PDZ_2) 		4 ARG A 153
GLY A 409
SER A 410
LEU A 149
 None
 1.28A 5bphA-1fc9A:
undetectable		 5bphA-1fc9A:
23.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1iov D-ALA:D-ALA LIGASE

(Escherichia
coli) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 LYS A 215
ARG A 255
GLY A 276
LEU A 282
 POB  A 321 (-2.5A)
POB  A 321 (-3.2A)
POB  A 321 (-3.2A)
POB  A 321 (-3.7A)
 0.90A 5bphA-1iovA:
18.3		 5bphA-1iovA:
73.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1iov D-ALA:D-ALA LIGASE

(Escherichia
coli) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		5 TYR A 210
LYS A 215
GLY A 276
SER A 281
LEU A 282
 None
POB  A 321 (-2.5A)
POB  A 321 (-3.2A)
POB  A 321 ( 2.2A)
POB  A 321 (-3.7A)
 0.77A 5bphA-1iovA:
18.3		 5bphA-1iovA:
73.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jsd HAEMAGGLUTININ (HA1
CHAIN)

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 TYR A  78
GLY A 266
SER A 265
LEU A  41
 None
 1.23A 5bphA-1jsdA:
undetectable		 5bphA-1jsdA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mt5 FATTY-ACID AMIDE
HYDROLASE

(Rattus
norvegicus) 		PF01425
(Amidase) 		4 TYR A 100
ARG A 285
GLY A 226
SER A 227
 None
 1.25A 5bphA-1mt5A:
2.0		 5bphA-1mt5A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1muu GDP-MANNOSE
6-DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		4 TYR A 211
GLY A  92
SER A  88
LEU A  94
 None
 0.90A 5bphA-1muuA:
4.0		 5bphA-1muuA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1taq TAQ DNA POLYMERASE

(Thermus
aquaticus) 		PF00476
(DNA_pol_A)
PF01367
(5_3_exonuc)
PF02739
(5_3_exonuc_N)
PF09281
(Taq-exonuc) 		4 TYR A  45
GLY A 279
SER A 280
LEU A 281
 None
 1.24A 5bphA-1taqA:
undetectable		 5bphA-1taqA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tfd TRANSFERRIN

(Oryctolagus
cuniculus) 		PF00405
(Transferrin) 		4 TYR A 188
ARG A 124
GLY A  65
SER A 125
 CO3  A 900 ( 3.6A)
CO3  A 900 (-3.5A)
None
CO3  A 900 (-4.1A)
 1.22A 5bphA-1tfdA:
undetectable		 5bphA-1tfdA:
25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wa8 ESAT-6 LIKE PROTEIN
ESXB

(Mycobacterium
bovis) 		PF06013
(WXG100) 		4 LYS A  65
GLY A  22
SER A  21
LEU A  24
 None
 1.14A 5bphA-1wa8A:
undetectable		 5bphA-1wa8A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp. KM) 		PF00480
(ROK) 		4 TYR A 198
GLY A 223
SER A 225
LEU A 149
 None
 1.25A 5bphA-1woqA:
undetectable		 5bphA-1woqA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x52 PELOTA HOMOLOG

(Homo sapiens) 		PF03465
(eRF1_3) 		4 TYR A  29
GLY A 108
SER A 104
LEU A 106
 None
 1.28A 5bphA-1x52A:
undetectable		 5bphA-1x52A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yy5 FMS1 PROTEIN

(Saccharomyces
cerevisiae) 		PF01593
(Amino_oxidase) 		4 TYR A  59
GLY A 368
SER A 364
LEU A 363
 None
 1.20A 5bphA-1yy5A:
3.5		 5bphA-1yy5A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT

(Lactococcus
lactis) 		PF13393
(tRNA-synt_His) 		4 LYS A 138
ARG A 103
GLY A 133
LEU A 131
 None
 1.07A 5bphA-1z7mA:
undetectable		 5bphA-1z7mA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2amc PHENYLALANYL-TRNA
SYNTHETASE ALPHA
CHAIN
PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Thermus
thermophilus;
Thermus
thermophilus) 		PF01409
(tRNA-synt_2d)
PF01409
(tRNA-synt_2d)
PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		4 TYR B 612
GLY B 595
SER A  94
LEU A  95
 None
 1.05A 5bphA-2amcB:
undetectable		 5bphA-2amcB:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ap1 PUTATIVE REGULATOR
PROTEIN

(Salmonella
enterica) 		PF00480
(ROK) 		4 TYR A 229
GLY A 254
SER A 256
LEU A 130
 None
 1.14A 5bphA-2ap1A:
undetectable		 5bphA-2ap1A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2azk GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE

(Sulfolobus
solfataricus) 		PF00348
(polyprenyl_synt) 		4 ARG A  45
GLY A 162
SER A 163
LEU A 164
 None
 1.22A 5bphA-2azkA:
undetectable		 5bphA-2azkA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bi7 UDP-GALACTOPYRANOSE
MUTASE

(Klebsiella
pneumoniae) 		PF03275
(GLF)
PF13450
(NAD_binding_8) 		4 TYR A 249
ARG A 343
GLY A 342
LEU A 344
 None
FAD  A1385 (-4.1A)
FAD  A1385 (-3.4A)
FAD  A1385 ( 4.7A)
 1.29A 5bphA-2bi7A:
4.0		 5bphA-2bi7A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bru NAD(P)
TRANSHYDROGENASE
SUBUNIT ALPHA

(Escherichia
coli) 		PF01262
(AlaDh_PNT_C)
PF05222
(AlaDh_PNT_N) 		4 ARG A1140
GLY A1317
SER A1323
LEU A1319
 None
 1.11A 5bphA-2bruA:
2.8		 5bphA-2bruA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c0k HEMOGLOBIN

(Gasterophilus
intestinalis) 		PF00042
(Globin) 		4 LYS A   1
GLY A  82
SER A  78
LEU A  77
 None
 1.19A 5bphA-2c0kA:
undetectable		 5bphA-2c0kA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d5r CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 7

(Homo sapiens) 		PF04857
(CAF1) 		4 LYS A  11
GLY A 222
SER A 229
LEU A 232
 None
 1.19A 5bphA-2d5rA:
undetectable		 5bphA-2d5rA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fv0 UNSATURATED
GLUCURONYL HYDROLASE

(Bacillus sp.
GL1) 		PF07470
(Glyco_hydro_88) 		4 TYR A 356
GLY A  90
SER A  94
LEU A  95
 None
 0.94A 5bphA-2fv0A:
undetectable		 5bphA-2fv0A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iab HYPOTHETICAL PROTEIN

(Streptomyces
avermitilis) 		PF01243
(Putative_PNPOx) 		4 ARG A 142
GLY A 141
SER A 140
LEU A 139
 None
 1.28A 5bphA-2iabA:
undetectable		 5bphA-2iabA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nx2 HYPOTHETICAL PROTEIN
YPSA

(Bacillus
subtilis) 		PF06908
(DUF1273) 		4 TYR A 164
GLY A  42
SER A   0
LEU A   1
 None
 1.20A 5bphA-2nx2A:
2.3		 5bphA-2nx2A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2plc PHOSPHATIDYLINOSITOL
-SPECIFIC
PHOSPHOLIPASE C

(Listeria
monocytogenes) 		PF00388
(PI-PLC-X) 		4 LYS A 293
GLY A 271
SER A  40
LEU A  39
 None
 0.97A 5bphA-2plcA:
undetectable		 5bphA-2plcA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ppq HOMOSERINE KINASE

(Agrobacterium
fabrum) 		PF01636
(APH) 		4 TYR A 176
ARG A 270
GLY A 271
LEU A 267
 None
 1.27A 5bphA-2ppqA:
undetectable		 5bphA-2ppqA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vl8 CYTOTOXIN L

(Paeniclostridium
sordellii) 		PF12918
(TcdB_N)
PF12919
(TcdA_TcdB) 		4 TYR A 330
GLY A 292
SER A 509
LEU A 290
 None
 1.27A 5bphA-2vl8A:
undetectable		 5bphA-2vl8A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w59 IGY FCU3-4

(Gallus gallus) 		PF07654
(C1-set) 		4 ARG A 448
GLY A 426
SER A 425
LEU A 424
 None
 1.28A 5bphA-2w59A:
undetectable		 5bphA-2w59A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wsu PUTATIVE FIBER
PROTEIN

(Porcine
mastadenovirus
B) 		PF00337
(Gal-bind_lectin) 		4 ARG A 453
GLY A 455
SER A 431
LEU A 432
 None
 1.06A 5bphA-2wsuA:
undetectable		 5bphA-2wsuA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ww2 ALPHA-1,2-MANNOSIDAS
E

(Bacteroides
thetaiotaomicron) 		PF07971
(Glyco_hydro_92) 		4 TYR A  75
GLY A  37
SER A 640
LEU A  35
 None
None
MPD  A 759 (-3.9A)
MPD  A 759 ( 4.0A)
 1.19A 5bphA-2ww2A:
undetectable		 5bphA-2ww2A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yf0 MYOTUBULARIN-RELATED
PROTEIN 6

(Homo sapiens) 		PF06602
(Myotub-related) 		4 LYS A 250
GLY A 254
SER A 208
LEU A 207
 None
 1.12A 5bphA-2yf0A:
undetectable		 5bphA-2yf0A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zal L-ASPARAGINASE

(Escherichia
coli) 		PF01112
(Asparaginase_2) 		4 TYR A  28
ARG A 149
GLY A  71
LEU A 148
 None
None
NA  A 800 ( 4.4A)
None
 1.04A 5bphA-2zalA:
undetectable		 5bphA-2zalA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b86 GENERAL
ODORANT-BINDING
PROTEIN LUSH

(Drosophila
melanogaster) 		PF01395
(PBP_GOBP) 		4 TYR A 107
LYS A 111
GLY A  34
LEU A  31
 None
 1.23A 5bphA-3b86A:
undetectable		 5bphA-3b86A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bga BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		4 TYR A 124
GLY A 486
SER A 448
LEU A 449
 None
 1.06A 5bphA-3bgaA:
undetectable		 5bphA-3bgaA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjq PHAGE-RELATED
PROTEIN

(Bordetella
bronchiseptica) 		PF03864
(Phage_cap_E) 		4 TYR A 136
GLY A 263
SER A 299
LEU A 298
 None
 1.14A 5bphA-3bjqA:
undetectable		 5bphA-3bjqA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmn PUTATIVE HYDROLASE

(Chloroflexus
aurantiacus) 		PF10103
(Zincin_2) 		4 TYR A 168
GLY A 180
SER A 181
LEU A 182
 None
 1.25A 5bphA-3cmnA:
undetectable		 5bphA-3cmnA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3euj CHROMOSOME PARTITION
PROTEIN MUKB, LINKER

([Haemophilus]
ducreyi) 		PF04310
(MukB)
PF13558
(SbcCD_C) 		4 TYR A1371
GLY A1362
SER A1337
LEU A1340
 None
 1.26A 5bphA-3eujA:
undetectable		 5bphA-3eujA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f08 UNCHARACTERIZED
PROTEIN Q6HG14

(Bacillus
thuringiensis) 		PF10604
(Polyketide_cyc2) 		4 ARG A  46
GLY A  23
SER A  26
LEU A  27
 None
 1.26A 5bphA-3f08A:
undetectable		 5bphA-3f08A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fmc PUTATIVE
SUCCINYLGLUTAMATE
DESUCCINYLASE /
ASPARTOACYLASE

(Shewanella
amazonensis) 		PF04952
(AstE_AspA) 		4 TYR A 289
LYS A 359
GLY A 173
SER A 176
 None
 1.26A 5bphA-3fmcA:
2.5		 5bphA-3fmcA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1l CYTOCHROME B
MITOCHONDRIAL
UBIQUINOL-CYTOCHROME
C REDUCTASE 14 KDA
PROTEIN

(Gallus gallus;
Gallus gallus) 		PF00032
(Cytochrom_B_C)
PF00033
(Cytochrome_B)
PF02271
(UCR_14kD) 		4 TYR F  20
GLY C 371
SER C 322
LEU C 321
 None
 1.20A 5bphA-3h1lF:
undetectable		 5bphA-3h1lF:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hig AMILORIDE-SENSITIVE
AMINE OXIDASE

(Homo sapiens) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 TYR A 627
LYS A  79
ARG A 517
LEU A 632
 None
CA  A 802 (-3.6A)
None
None
 1.25A 5bphA-3higA:
undetectable		 5bphA-3higA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hnp OXIDOREDUCTASE

(Bacillus cereus) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 TYR A 155
GLY A 170
SER A 174
LEU A 175
 None
 0.87A 5bphA-3hnpA:
undetectable		 5bphA-3hnpA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jvv TWITCHING MOBILITY
PROTEIN

(Pseudomonas
aeruginosa) 		PF00437
(T2SSE) 		4 ARG A 276
GLY A 133
SER A 134
LEU A 268
 ACP  A 400 (-3.5A)
ACP  A 400 (-3.9A)
ACP  A 400 (-3.5A)
ACP  A 400 (-4.6A)
 1.20A 5bphA-3jvvA:
undetectable		 5bphA-3jvvA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k30 HISTAMINE
DEHYDROGENASE

(Pimelobacter
simplex) 		PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2) 		4 TYR A 535
GLY A 443
SER A 434
LEU A 439
 None
 1.17A 5bphA-3k30A:
7.8		 5bphA-3k30A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kew DHHA1 DOMAIN PROTEIN

(Clostridium
perfringens) 		PF01411
(tRNA-synt_2c)
PF07973
(tRNA_SAD) 		4 TYR A 157
LYS A 155
GLY A 187
LEU A 190
 None
 1.15A 5bphA-3kewA:
undetectable		 5bphA-3kewA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kio RIBONUCLEASE H2
SUBUNIT A

(Mus musculus) 		PF01351
(RNase_HII) 		4 ARG A  13
GLY A  12
SER A  98
LEU A  97
 None
 0.87A 5bphA-3kioA:
undetectable		 5bphA-3kioA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3krz NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE

(Thermoanaerobacter
pseudethanolicus) 		PF00724
(Oxidored_FMN) 		4 TYR A 112
ARG A  66
GLY A  33
SER A  30
 None
 1.24A 5bphA-3krzA:
undetectable		 5bphA-3krzA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lwu SUCCINYLGLUTAMATE
DESUCCINYLASE/ASPART
OACYLASE

(Shewanella
frigidimarina) 		PF04952
(AstE_AspA) 		4 TYR A 291
LYS A 361
GLY A 175
SER A 178
 UNL  A 373 ( 4.4A)
UNL  A 373 ( 2.9A)
UNL  A 373 ( 3.5A)
None
 1.23A 5bphA-3lwuA:
2.0		 5bphA-3lwuA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mcx SUSD SUPERFAMILY
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ARG A 189
GLY A 161
SER A 171
LEU A 172
 None
 1.26A 5bphA-3mcxA:
undetectable		 5bphA-3mcxA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3myv SUSD SUPERFAMILY
PROTEIN

(Bacteroides
vulgatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ARG A 183
GLY A 155
SER A 165
LEU A 166
 None
 1.14A 5bphA-3myvA:
undetectable		 5bphA-3myvA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odn DALLY-LIKE PROTEIN

(Drosophila
melanogaster) 		PF01153
(Glypican) 		4 LYS A 153
GLY A 148
SER A 281
LEU A 150
 None
 1.23A 5bphA-3odnA:
undetectable		 5bphA-3odnA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo sapiens) 		PF00057
(Ldl_recept_a)
PF00090
(TSP_1)
PF01823
(MACPF) 		4 TYR B 165
GLY B 119
SER B 120
LEU B 121
 None
 1.23A 5bphA-3ojyB:
undetectable		 5bphA-3ojyB:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p56 RIBONUCLEASE H2
SUBUNIT A

(Homo sapiens) 		PF01351
(RNase_HII) 		4 ARG A  13
GLY A  12
SER A  97
LEU A  96
 None
 0.86A 5bphA-3p56A:
undetectable		 5bphA-3p56A:
22.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3r5x D-ALANINE--D-ALANINE
LIGASE

(Bacillus
anthracis) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ARG A 246
GLY A 266
SER A 271
LEU A 272
 None
 0.59A 5bphA-3r5xA:
33.3		 5bphA-3r5xA:
37.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B

(Bacillus
subtilis) 		PF12705
(PDDEXK_1) 		4 TYR B 655
ARG B   9
GLY B   8
SER B  12
 None
 1.12A 5bphA-3u44B:
2.5		 5bphA-3u44B:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ukn NOVEL PROTEIN
SIMILAR TO
VERTEBRATE POTASSIUM
VOLTAGE-GATED
CHANNEL, SUBFAMILY H
(EAG-RELATED) FAMILY

(Danio rerio) 		PF00027
(cNMP_binding) 		4 ARG A 717
GLY A 715
SER A 712
LEU A 713
 None
 1.23A 5bphA-3uknA:
undetectable		 5bphA-3uknA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v4c ALDEHYDE
DEHYDROGENASE
(NADP+)

(Sinorhizobium
meliloti) 		PF00171
(Aldedh) 		4 TYR A 466
GLY A 243
SER A 240
LEU A 264
 None
 1.27A 5bphA-3v4cA:
3.6		 5bphA-3v4cA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w01 HEPTAPRENYLGLYCERYL
PHOSPHATE SYNTHASE

(Staphylococcus
aureus) 		PF01884
(PcrB) 		4 TYR A 213
LYS A  17
GLY A  38
LEU A  13
 None
 1.02A 5bphA-3w01A:
undetectable		 5bphA-3w01A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wdb PROBABLE
ATP-DEPENDENT CLP
PROTEASE ATP-BINDING
SUBUNIT

(Mycobacterium
tuberculosis) 		PF02861
(Clp_N) 		4 ARG A  60
GLY A  58
SER A  55
LEU A  56
 None
 1.19A 5bphA-3wdbA:
undetectable		 5bphA-3wdbA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4avc LYSINE
ACETYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF00027
(cNMP_binding)
PF13302
(Acetyltransf_3) 		4 TYR A 182
GLY A 297
SER A 275
LEU A 274
 None
 1.26A 5bphA-4avcA:
undetectable		 5bphA-4avcA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ce4 MRPL39

(Sus scrofa) 		no annotation 4 LYS c 156
ARG c 165
SER c 162
LEU c 163
 None
 1.12A 5bphA-4ce4c:
undetectable		 5bphA-4ce4c:
22.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4egj D-ALANINE--D-ALANINE
LIGASE

(Paraburkholderia
xenovorans) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ARG A 260
GLY A 281
SER A 286
LEU A 287
 None
 0.40A 5bphA-4egjA:
37.0		 5bphA-4egjA:
49.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ei0 UNCHARACTERIZED
HYPOTHETICAL PROTEIN

(Parabacteroides
merdae) 		PF14725
(DUF4466) 		4 TYR A 231
GLY A 294
SER A 227
LEU A 226
 None
 1.05A 5bphA-4ei0A:
undetectable		 5bphA-4ei0A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eps HYPOTHETICAL PROTEIN

(Bacteroides
ovatus) 		PF13149
(Mfa_like_1) 		4 TYR A 509
GLY A 459
SER A 458
LEU A 461
 None
 1.21A 5bphA-4epsA:
undetectable		 5bphA-4epsA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gei THIOREDOXIN-INTERACT
ING PROTEIN

(Homo sapiens) 		PF00339
(Arrestin_N) 		4 TYR A 123
GLY A 108
SER A  23
LEU A 105
 None
 1.17A 5bphA-4geiA:
undetectable		 5bphA-4geiA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h98 DIHYDROFOLATE
REDUCTASE

([Candida]
glabrata) 		PF00186
(DHFR_1) 		4 TYR A  35
GLY A 199
SER A 170
LEU A 173
 None
 1.02A 5bphA-4h98A:
undetectable		 5bphA-4h98A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l0c DEFORMYLASE

(Pseudomonas
putida) 		PF12697
(Abhydrolase_6) 		4 ARG A  57
GLY A  58
SER A  64
LEU A  67
 None
None
ACY  A 302 (-3.4A)
None
 1.28A 5bphA-4l0cA:
2.6		 5bphA-4l0cA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mx8 PERIPLASMIC BINDING
PROTEIN

(Xylanimonas
cellulosilytica) 		PF01497
(Peripla_BP_2) 		4 TYR A  17
GLY A 110
SER A 130
LEU A 129
 None
 1.14A 5bphA-4mx8A:
4.2		 5bphA-4mx8A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nae HEPTAPRENYLGLYCERYL
PHOSPHATE SYNTHASE

(Geobacillus
kaustophilus) 		PF01884
(PcrB) 		4 TYR A 213
LYS A  17
GLY A  38
LEU A  13
 None
 1.05A 5bphA-4naeA:
undetectable		 5bphA-4naeA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4piv FATTY ACID SYNTHASE

(Homo sapiens) 		PF08242
(Methyltransf_12)
PF08659
(KR) 		4 ARG A1953
GLY A1951
SER A1948
LEU A1949
 None
 1.29A 5bphA-4pivA:
undetectable		 5bphA-4pivA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pz7 MRNA-CAPPING ENZYME
SUBUNIT ALPHA

(Schizosaccharomyces
pombe) 		PF01331
(mRNA_cap_enzyme)
PF03919
(mRNA_cap_C) 		4 TYR A 230
ARG A  72
GLY A 125
LEU A  74
 None
GPL  A  67 (-4.6A)
None
None
 1.21A 5bphA-4pz7A:
undetectable		 5bphA-4pz7A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkr TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Arthrobacter
sp. FB24) 		PF13377
(Peripla_BP_3) 		4 TYR A  84
GLY A 305
SER A  91
LEU A 301
 LBT  A 401 ( 3.7A)
None
None
None
 1.24A 5bphA-4rkrA:
6.7		 5bphA-4rkrA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rwy ANTIBODY 8ANC131
HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 TYR H 194
GLY H 134
SER H 187
LEU H 189
 None
 1.19A 5bphA-4rwyH:
undetectable		 5bphA-4rwyH:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tz5 PUTATIVE SECRETED
PROTEIN

(Streptomyces
sp. SirexAA-E) 		no annotation 4 TYR A 505
GLY A 576
SER A 573
LEU A 574
 BGC  A 702 (-4.6A)
None
None
BGC  A 702 ( 4.0A)
 1.04A 5bphA-4tz5A:
undetectable		 5bphA-4tz5A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uar PROTEIN CBBY

(Rhodobacter
sphaeroides) 		PF13419
(HAD_2) 		4 ARG A 182
GLY A 180
SER A 177
LEU A 178
 None
 1.25A 5bphA-4uarA:
2.8		 5bphA-4uarA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upl SULFATASE FAMILY
PROTEIN

(Ruegeria
pomeroyi) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		4 ARG A 121
GLY A 119
SER A 116
LEU A 117
 None
 1.24A 5bphA-4uplA:
undetectable		 5bphA-4uplA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yfz OUTER CAPSID PROTEIN
VP4

(Rotavirus A) 		no annotation 4 LYS A 222
GLY A 184
SER A 180
LEU A 186
 None
None
NAG  A1002 (-4.1A)
None
 1.28A 5bphA-4yfzA:
undetectable		 5bphA-4yfzA:
17.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4zqi D-ALANINE--D-ALANINE
LIGASE

(Yersinia pestis) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ARG A 255
GLY A 276
SER A 281
LEU A 282
 None
 0.21A 5bphA-4zqiA:
46.0		 5bphA-4zqiA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a29 EXOPOLYGALACTURONATE
LYASE

(Vibrio
vulnificus) 		PF06917
(Pectate_lyase_2) 		4 TYR A 481
GLY A 442
SER A 443
LEU A 444
 None
None
EDO  A1580 (-4.3A)
None
 1.24A 5bphA-5a29A:
undetectable		 5bphA-5a29A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a31 ANAPHASE-PROMOTING
COMPLEX SUBUNIT 5

(Homo sapiens) 		PF12862
(ANAPC5) 		4 ARG O 298
GLY O 297
SER O 299
LEU O 283
 None
 1.25A 5bphA-5a31O:
undetectable		 5bphA-5a31O:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5amz THAUMATIN-1

(Thaumatococcus
daniellii) 		PF00314
(Thaumatin) 		4 TYR A 199
GLY A  47
SER A  91
LEU A  92
 None
 1.19A 5bphA-5amzA:
undetectable		 5bphA-5amzA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5amz THAUMATIN-1

(Thaumatococcus
daniellii) 		PF00314
(Thaumatin) 		4 TYR A 199
GLY A  48
SER A  91
LEU A  92
 None
 1.18A 5bphA-5amzA:
undetectable		 5bphA-5amzA:
20.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dmx D-ALANINE--D-ALANINE
LIGASE

(Acinetobacter
baumannii) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ARG A 253
GLY A 274
SER A 279
LEU A 280
 None
 0.46A 5bphA-5dmxA:
31.3		 5bphA-5dmxA:
53.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gx8 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Streptobacillus
moniliformis) 		PF13416
(SBP_bac_8) 		4 TYR A  74
GLY A 327
SER A  92
LEU A  95
 None
 1.23A 5bphA-5gx8A:
undetectable		 5bphA-5gx8A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hu7 PUTATIVE POLYKETIDE
SYNTHASE

(Brevibacillus
brevis) 		PF14765
(PS-DH) 		4 LYS A3111
GLY A3131
SER A3102
LEU A3114
 None
 1.20A 5bphA-5hu7A:
undetectable		 5bphA-5hu7A:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i5h INNER MEMBRANE
PROTEIN YEJM

(Escherichia
coli) 		PF00884
(Sulfatase)
PF11893
(DUF3413) 		4 TYR A 311
GLY A 320
SER A 323
LEU A 322
 None
 1.23A 5bphA-5i5hA:
undetectable		 5bphA-5i5hA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii) 		PF00150
(Cellulase) 		4 TYR A 268
GLY A 312
SER A 311
LEU A 314
 None
 1.01A 5bphA-5ihsA:
undetectable		 5bphA-5ihsA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzs FERRIC ENTEROBACTIN
RECEPTOR

(Pseudomonas
aeruginosa) 		no annotation 4 ARG A 296
GLY A 297
SER A 304
LEU A 305
 None
 1.02A 5bphA-5mzsA:
undetectable		 5bphA-5mzsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nri D-ALANINE--D-ALANINE
LIGASE

(Burkholderia
pseudomallei) 		no annotation 5 TYR A 215
ARG A 260
GLY A 281
SER A 286
LEU A 287
 None
DAL  A 402 (-4.1A)
DAL  A 402 (-4.3A)
DAL  A 402 (-3.6A)
DAL  A 402 (-3.8A)
 0.72A 5bphA-5nriA:
39.8		 5bphA-5nriA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1

(Glycine max) 		no annotation 4 TYR A 317
GLY A 258
SER A 261
LEU A 262
 None
 1.09A 5bphA-5tr0A:
undetectable		 5bphA-5tr0A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v1w GLYCOSIDE HYDROLASE

(Bacillus
halodurans) 		PF03639
(Glyco_hydro_81) 		4 TYR A 176
GLY A  82
SER A  83
LEU A  84
 None
 1.20A 5bphA-5v1wA:
undetectable		 5bphA-5v1wA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wqs BETA-AMYLASE

(Ipomoea batatas) 		no annotation 4 TYR A 155
GLY A 139
SER A 137
LEU A 136
 None
 1.12A 5bphA-5wqsA:
undetectable		 5bphA-5wqsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjy ATP-BINDING CASSETTE
SUB-FAMILY A MEMBER
1

(Homo sapiens) 		PF00005
(ABC_tran)
PF12698
(ABC2_membrane_3) 		4 ARG A1503
GLY A1502
SER A1392
LEU A1500
 None
 1.29A 5bphA-5xjyA:
undetectable		 5bphA-5xjyA:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xpg UNCHARACTERIZED
PROTEIN

(Thermus
thermophilus) 		no annotation 4 TYR A 171
ARG A 286
GLY A 612
LEU A 281
 None
 1.00A 5bphA-5xpgA:
6.0		 5bphA-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsy SODIUM CHANNEL
PROTEIN

(Electrophorus
electricus) 		PF00520
(Ion_trans)
PF06512
(Na_trans_assoc) 		4 TYR A1243
GLY A1202
SER A1205
LEU A1206
 None
 1.26A 5bphA-5xsyA:
undetectable		 5bphA-5xsyA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zal ENDORIBONUCLEASE
DICER

(Homo sapiens) 		no annotation 4 TYR A1335
GLY A1341
SER A1344
LEU A1343
 None
 1.04A 5bphA-5zalA:
undetectable		 5bphA-5zalA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6brs PUTATIVE ZINC
PROTEASE

(Pectobacterium
atrosepticum) 		no annotation 4 TYR A 700
GLY A 506
SER A 525
LEU A 524
 None
 1.28A 5bphA-6brsA:
undetectable		 5bphA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1

(Homo sapiens) 		no annotation 4 LYS A 364
GLY A 342
SER A 338
LEU A 339
 None
 1.08A 5bphA-6f9nA:
undetectable		 5bphA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus) 		no annotation 4 ARG A1289
GLY A1346
SER A1343
LEU A1344
 None
 1.22A 5bphA-6fb3A:
undetectable		 5bphA-6fb3A:
undetectable