SIMILAR PATTERNS OF AMINO ACIDS FOR 5BOJ_B_4TXB201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhb BACTERIORHODOPSIN

(Halobacterium
salinarum) 		PF01036
(Bac_rhodopsin) 		4 LEU A  25
THR A  55
LEU A  22
THR A  17
 None
 0.96A 5bojB-1bhbA:
undetectable		 5bojB-1bhbA:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gke TRANSTHYRETIN

(Rattus
norvegicus) 		PF00576
(Transthyretin) 		7 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.51A 5bojB-1gkeA:
21.2		 5bojB-1gkeA:
83.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hww ALPHA-MANNOSIDASE II

(Drosophila
melanogaster) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid) 		4 LEU A 651
THR A 606
LEU A 746
SER A 757
 None
 0.97A 5bojB-1hwwA:
undetectable		 5bojB-1hwwA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k25 LOW-AFFINITY
PENICILLIN-BINDING
PROTEIN 2X

(Streptococcus
pneumoniae) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer)
PF03793
(PASTA) 		4 LEU A 585
ALA A 291
LEU A 293
THR A 305
 None
 0.78A 5bojB-1k25A:
0.0		 5bojB-1k25A:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nsa PROCARBOXYPEPTIDASE
B

(Sus scrofa) 		PF00246
(Peptidase_M14)
PF02244
(Propep_M14) 		4 LEU A 108
THR A  41
LEU A  49
SER A  36
 None
 1.02A 5bojB-1nsaA:
undetectable		 5bojB-1nsaA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Thermus
thermophilus) 		PF01467
(CTP_transf_like) 		4 THR A  31
ALA A  33
LEU A  35
SER A   8
 None
None
PNS  A1161 (-3.7A)
PNS  A1161 (-3.0A)
 0.80A 5bojB-1od6A:
undetectable		 5bojB-1od6A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qhv PROTEIN (ADENOVIRUS
FIBRE)

(Human
mastadenovirus
C) 		PF00541
(Adeno_knob) 		4 THR A 435
ALA A 437
LEU A 439
THR A 422
 None
 0.80A 5bojB-1qhvA:
undetectable		 5bojB-1qhvA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rzv GLYCOGEN SYNTHASE 1

(Agrobacterium
tumefaciens) 		PF00534
(Glycos_transf_1)
PF08323
(Glyco_transf_5) 		4 LEU A 430
THR A 437
ALA A 433
SER A 423
 None
 0.95A 5bojB-1rzvA:
undetectable		 5bojB-1rzvA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s2n EXTRACELLULAR
SUBTILISIN-LIKE
SERINE PROTEINASE

(Vibrio sp.
PA-44) 		PF00082
(Peptidase_S8) 		4 LEU A 129
THR A 175
ALA A 154
THR A 219
 None
None
PMS  A1284 ( 3.8A)
PMS  A1284 (-4.6A)
 1.01A 5bojB-1s2nA:
undetectable		 5bojB-1s2nA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sn2 TRANSTHYRETIN

(Sparus aurata) 		PF00576
(Transthyretin) 		6 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
THR A 119
 None
 0.63A 5bojB-1sn2A:
20.9		 5bojB-1sn2A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tfp TRANSTHYRETIN

(Gallus gallus) 		PF00576
(Transthyretin) 		6 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
THR A 119
 None
 0.65A 5bojB-1tfpA:
18.9		 5bojB-1tfpA:
73.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uun MSPA

(Mycolicibacterium
smegmatis) 		PF09203
(MspA) 		4 LEU A  62
ALA A 164
LEU A 166
THR A 176
 None
 0.60A 5bojB-1uunA:
undetectable		 5bojB-1uunA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wyd HYPOTHETICAL
ASPARTYL-TRNA
SYNTHETASE

(Sulfurisphaera
tokodaii) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		4 THR A 147
ALA A 143
LEU A 139
SER A 138
 None
 1.03A 5bojB-1wydA:
undetectable		 5bojB-1wydA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yr2 PROLYL
OLIGOPEPTIDASE

(Novosphingobium
capsulatum) 		PF00326
(Peptidase_S9)
PF02897
(Peptidase_S9_N) 		4 LEU A 684
ALA A 649
LEU A 651
SER A 596
 None
 0.71A 5bojB-1yr2A:
undetectable		 5bojB-1yr2A:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b6n PROTEINASE K

(Serratia sp.
GF96) 		PF00082
(Peptidase_S8) 		4 LEU A 133
THR A 179
ALA A 158
THR A 223
 None
 1.03A 5bojB-2b6nA:
undetectable		 5bojB-2b6nA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bdw HYPOTHETICAL PROTEIN
K11E8.1D

(Caenorhabditis
elegans) 		PF00069
(Pkinase) 		4 THR A 305
ALA A 309
LEU A 313
SER A 314
 None
 1.03A 5bojB-2bdwA:
undetectable		 5bojB-2bdwA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN

(Torpedo
marmorata) 		PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb) 		4 THR E 468
ALA E 464
LEU E 460
SER E 459
 None
 0.99A 5bojB-2bg9E:
undetectable		 5bojB-2bg9E:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2csd TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24)
PF14520
(HHH_5) 		4 LEU A 207
THR A 198
LEU A 209
SER A 210
 None
 0.98A 5bojB-2csdA:
undetectable		 5bojB-2csdA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7b OBSCURIN

(Homo sapiens) 		PF07679
(I-set) 		4 LEU A  18
THR A  87
ALA A  89
LEU A  91
 None
 0.86A 5bojB-2e7bA:
undetectable		 5bojB-2e7bA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyq TRANSCRIPTION-REPAIR
COUPLING FACTOR

(Escherichia
coli) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02559
(CarD_CdnL_TRCF)
PF03461
(TRCF) 		4 LEU A 939
ALA A 910
LEU A 784
SER A 906
 EPE  A1151 (-4.0A)
None
None
EPE  A1152 (-2.8A)
 0.99A 5bojB-2eyqA:
undetectable		 5bojB-2eyqA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2

(Mus musculus) 		PF00076
(RRM_1)
PF07078
(FYTT) 		4 LEU A 149
THR A  73
ALA A  75
LEU A  77
 None
 0.83A 5bojB-2f3jA:
undetectable		 5bojB-2f3jA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f5a PROTEIN (ANTIBODY
2F5 (LIGHT CHAIN))

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.84A 5bojB-2f5aL:
undetectable		 5bojB-2f5aL:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ftp HYDROXYMETHYLGLUTARY
L-COA LYASE

(Pseudomonas
aeruginosa) 		PF00682
(HMGL-like) 		4 THR A  76
ALA A  78
LEU A  80
SER A  49
 None
 0.85A 5bojB-2ftpA:
undetectable		 5bojB-2ftpA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h8h PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC

(Homo sapiens) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		4 LYS A 295
LEU A 297
THR A 338
SER A 330
 H8H  A 534 (-3.7A)
None
H8H  A 534 (-3.1A)
None
 0.81A 5bojB-2h8hA:
undetectable		 5bojB-2h8hA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iou PERTACTIN
EXTRACELLULAR DOMAIN

(Bordetella
bronchiseptica) 		PF03212
(Pertactin) 		4 THR G 129
ALA G 131
SER G 101
THR G  99
 None
 0.94A 5bojB-2iouG:
undetectable		 5bojB-2iouG:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iyo 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING

(Lactococcus
lactis) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 LEU A 205
THR A 236
LEU A 211
SER A 212
 None
 1.01A 5bojB-2iyoA:
undetectable		 5bojB-2iyoA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jre C60-1 PDZ DOMAIN
PEPTIDE

(-) 		PF00595
(PDZ) 		4 LYS A  68
LEU A  70
LEU A  99
SER A  15
 None
 0.80A 5bojB-2jreA:
undetectable		 5bojB-2jreA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kfu RV1827 PTHR 22

(Mycobacterium
tuberculosis) 		PF00498
(FHA) 		4 LEU A  89
THR A  77
ALA A  79
SER A 115
 None
 0.65A 5bojB-2kfuA:
undetectable		 5bojB-2kfuA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kkl UNCHARACTERIZED
PROTEIN MB1858

(Mycobacterium
bovis) 		PF00498
(FHA) 		4 LEU A  89
THR A  77
ALA A  79
SER A  95
 None
 0.88A 5bojB-2kklA:
undetectable		 5bojB-2kklA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mi6 TRANSCRIPTION
TERMINATION/ANTITERM
INATION PROTEIN NUSG

(Mycobacterium
tuberculosis) 		no annotation 4 THR A  16
ALA A  27
LEU A  42
SER A  30
 None
 1.05A 5bojB-2mi6A:
undetectable		 5bojB-2mi6A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nlz CEPHALOSPORIN
ACYLASE

(Bacillus
halodurans) 		PF01019
(G_glu_transpept) 		4 LEU A 208
ALA A  57
LEU A 142
SER A 141
 None
 0.99A 5bojB-2nlzA:
undetectable		 5bojB-2nlzA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pv7 T-PROTEIN [INCLUDES:
CHORISMATE MUTASE
(EC 5.4.99.5) (CM)
AND PREPHENATE
DEHYDROGENASE (EC
1.3.1.12) (PDH)]

(Haemophilus
influenzae) 		PF02153
(PDH) 		4 LEU A 199
ALA A 175
LEU A 177
SER A 151
 None
None
None
NAD  A 400 (-3.8A)
 0.93A 5bojB-2pv7A:
undetectable		 5bojB-2pv7A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7g UROCANATE HYDRATASE

(Pseudomonas
putida) 		PF01175
(Urocanase)
PF17391
(Urocanase_N)
PF17392
(Urocanase_C) 		4 LEU A 171
THR A 265
ALA A 173
LEU A 194
 None
NAD  A3001 (-4.2A)
NAD  A3001 ( 4.4A)
None
 0.98A 5bojB-2v7gA:
1.4		 5bojB-2v7gA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9t SLIT HOMOLOG 2
PROTEIN N-PRODUCT

(Homo sapiens) 		PF01462
(LRRNT)
PF01463
(LRRCT)
PF13855
(LRR_8) 		4 LEU B 363
THR B 415
ALA B 391
LEU B 367
 None
 0.83A 5bojB-2v9tB:
undetectable		 5bojB-2v9tB:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9u MSPA

(Mycolicibacterium
smegmatis) 		PF09203
(MspA) 		4 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.58A 5bojB-2v9uA:
3.1		 5bojB-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyg 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING

(Klebsiella
pneumoniae) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 LEU A 204
THR A 235
LEU A 210
SER A 211
 None
 0.79A 5bojB-2zygA:
undetectable		 5bojB-2zygA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afg SUBTILISIN-LIKE
SERINE PROTEASE

(Thermococcus
kodakarensis) 		PF00082
(Peptidase_S8)
PF04151
(PPC) 		4 LEU A 248
THR A 299
ALA A 277
THR A 358
 None
 1.04A 5bojB-3afgA:
undetectable		 5bojB-3afgA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdw NKG2-A/NKG2-B TYPE
II INTEGRAL MEMBRANE
PROTEIN

(Homo sapiens) 		PF00059
(Lectin_C) 		4 LEU B 216
ALA B 209
LEU B 211
SER B 173
 None
 0.93A 5bojB-3bdwB:
undetectable		 5bojB-3bdwB:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LYS A  46
ALA A  44
LEU A  40
SER A  41
 None
 0.80A 5bojB-3bjlA:
undetectable		 5bojB-3bjlA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3blw ISOCITRATE
DEHYDROGENASE [NAD]
SUBUNIT 1

(Saccharomyces
cerevisiae) 		PF00180
(Iso_dh) 		4 LEU A 125
THR A 235
SER A 177
THR A 179
 None
 0.79A 5bojB-3blwA:
undetectable		 5bojB-3blwA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3d LYSOZYME

(Escherichia
virus Lambda) 		PF00959
(Phage_lysozyme) 		4 LEU A  12
LEU A  15
SER A  18
THR A  21
 None
 0.99A 5bojB-3d3dA:
undetectable		 5bojB-3d3dA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3deg GTP-BINDING PROTEIN
LEPA

(Escherichia
coli) 		PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF03144
(GTP_EFTU_D2)
PF06421
(LepA_C) 		4 LEU C 237
THR C  60
LEU C 258
SER C 208
 None
 0.76A 5bojB-3degC:
undetectable		 5bojB-3degC:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epd POLIOVIRUS RECEPTOR

(Homo sapiens) 		PF07686
(V-set)
PF08205
(C2-set_2) 		4 THR R  65
ALA R  67
SER R 120
THR R 122
 None
 0.90A 5bojB-3epdR:
undetectable		 5bojB-3epdR:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f7o SERINE PROTEASE

(Purpureocillium
lilacinum) 		PF00082
(Peptidase_S8) 		4 LEU A 136
THR A 182
ALA A 161
THR A 226
 None
CA  A 286 (-3.6A)
None
None
 1.05A 5bojB-3f7oA:
undetectable		 5bojB-3f7oA:
18.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fc8 TRANSTHYRETIN

(Homo sapiens) 		PF00576
(Transthyretin) 		7 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
SER A 117
THR A 119
 IFA  A3000 (-3.0A)
IFA  A3000 ( 4.7A)
IFA  A3000 (-4.9A)
IFA  A3000 (-3.1A)
IFA  A3000 (-4.1A)
IFA  A3000 (-3.9A)
IFA  A3000 ( 4.9A)
 0.46A 5bojB-3fc8A:
22.8		 5bojB-3fc8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gcw PROPROTEIN
CONVERTASE
SUBTILISIN/KEXIN
TYPE 9

(Homo sapiens) 		PF00082
(Peptidase_S8) 		4 LEU A 289
THR A 335
ALA A 314
THR A 385
 None
 1.03A 5bojB-3gcwA:
undetectable		 5bojB-3gcwA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE

(Staphylococcus
aureus) 		PF00698
(Acyl_transf_1) 		4 LYS A 152
LEU A 173
LEU A 147
SER A 146
 None
 1.04A 5bojB-3im9A:
undetectable		 5bojB-3im9A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m7g TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13404
(HTH_AsnC-type) 		4 LEU A 207
THR A 198
LEU A 209
SER A 210
 None
 0.87A 5bojB-3m7gA:
undetectable		 5bojB-3m7gA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pqj BIOFILM
GROWTH-ASSOCIATED
REPRESSOR

(Xylella
fastidiosa) 		PF12840
(HTH_20) 		4 LEU A  72
LEU A  69
SER A  66
THR A  64
 None
 1.02A 5bojB-3pqjA:
undetectable		 5bojB-3pqjA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6s CERJ

(Streptomyces
tendae) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.93A 5bojB-3t6sA:
undetectable		 5bojB-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uxj NADPH-DEPENDENT
7-CYANO-7-DEAZAGUANI
NE REDUCTASE

(Vibrio cholerae) 		PF14489
(QueF)
PF14819
(QueF_N) 		4 LYS A  96
LEU A 100
LEU A  35
SER A  34
 NAP  A 291 (-3.1A)
None
None
None
 0.95A 5bojB-3uxjA:
undetectable		 5bojB-3uxjA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aq9 ACETYLCHOLINE
RECEPTOR GAMMA
SUBUNIT

(Torpedo
marmorata) 		PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb) 		4 THR E 468
ALA E 464
LEU E 460
SER E 459
 None
 0.92A 5bojB-4aq9E:
undetectable		 5bojB-4aq9E:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bed HEMOCYANIN KLH1

(Megathura
crenulata) 		PF00264
(Tyrosinase)
PF14830
(Haemocyan_bet_s) 		4 THR A 759
ALA A 761
LEU A 763
THR A 604
 None
 0.97A 5bojB-4bedA:
undetectable		 5bojB-4bedA:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bug ANCILLARY PROTEIN 1

(Streptococcus
pyogenes) 		PF08341
(TED) 		4 LEU A 608
THR A 681
LEU A 711
THR A 699
 None
 0.98A 5bojB-4bugA:
6.7		 5bojB-4bugA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cak INTEGRIN ALPHA-IIB

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 THR A 548
ALA A 550
LEU A 552
SER A 483
 None
 0.81A 5bojB-4cakA:
undetectable		 5bojB-4cakA:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ctd OUTER MEMBRANE
PROTEIN G

(Escherichia
coli) 		PF09381
(Porin_OmpG) 		4 LEU A 167
ALA A 195
LEU A 197
THR A 210
 None
None
None
CL  A1274 (-4.2A)
 0.62A 5bojB-4ctdA:
undetectable		 5bojB-4ctdA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d9i DIAMINOPROPIONATE
AMMONIA-LYASE

(Escherichia
coli) 		PF00291
(PALP) 		4 LYS A  61
LEU A  63
LEU A 372
THR A 225
 None
 1.04A 5bojB-4d9iA:
undetectable		 5bojB-4d9iA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dmo N-HYDROXYARYLAMINE
O-ACETYLTRANSFERASE

(Bacillus cereus) 		PF00797
(Acetyltransf_2) 		4 LEU A 233
THR A 221
ALA A 226
LEU A 228
 None
 0.95A 5bojB-4dmoA:
undetectable		 5bojB-4dmoA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gfj TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24)
PF14520
(HHH_5) 		4 LEU A 207
THR A 198
LEU A 209
SER A 210
 None
 0.91A 5bojB-4gfjA:
undetectable		 5bojB-4gfjA:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gga CELL DIVISION CYCLE
PROTEIN 20 HOMOLOG

(Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 THR A 457
ALA A 459
SER A 448
THR A 450
 None
 0.68A 5bojB-4ggaA:
undetectable		 5bojB-4ggaA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 14

(Thermus
thermophilus) 		PF00361
(Proton_antipo_M) 		4 THR N 123
ALA N 120
LEU N 116
SER N 115
 None
 1.02A 5bojB-4heaN:
undetectable		 5bojB-4heaN:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hfo BIOGENIC
AMINE-BINDING
PROTEIN

(Rhodnius
prolixus) 		PF02087
(Nitrophorin) 		4 LEU A 187
LEU A  46
SER A  22
THR A  20
 None
 1.04A 5bojB-4hfoA:
undetectable		 5bojB-4hfoA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iv6 ACYL-COA
DEHYDROGENASE FADE3

(Mycolicibacterium
smegmatis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 THR A 250
ALA A 322
LEU A 320
THR A 325
 None
 1.05A 5bojB-4iv6A:
undetectable		 5bojB-4iv6A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mr0 PLASMIN AND
FIBRONECTIN-BINDING
PROTEIN A

(Streptococcus
pneumoniae) 		PF12708
(Pectate_lyase_3)
PF13229
(Beta_helix) 		4 LYS A 426
LEU A 424
ALA A 470
THR A 503
 None
CA  A 702 ( 4.5A)
None
None
 0.79A 5bojB-4mr0A:
undetectable		 5bojB-4mr0A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n14 CELL DIVISION CYCLE
PROTEIN 20 HOMOLOG

(Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 THR A 457
ALA A 459
SER A 448
THR A 450
 None
 0.72A 5bojB-4n14A:
undetectable		 5bojB-4n14A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o38 CYCLIN-G-ASSOCIATED
KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		4 LYS A  69
LEU A  71
THR A 123
SER A 106
 None
 0.69A 5bojB-4o38A:
undetectable		 5bojB-4o38A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pgw UNCHARACTERIZED
PROTEIN YETJ

(Bacillus
subtilis) 		PF01027
(Bax1-I) 		4 LEU A  81
THR A  23
ALA A  27
LEU A  31
 None
 1.04A 5bojB-4pgwA:
undetectable		 5bojB-4pgwA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qyb UNCHARACTERIZED
PROTEIN

(Burkholderia
cenocepacia) 		PF10765
(DUF2591) 		4 LEU A  98
ALA A 102
SER A  94
THR A 105
 None
 0.86A 5bojB-4qybA:
undetectable		 5bojB-4qybA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tr6 DNA POLYMERASE III
SUBUNIT BETA

(Bacillus
subtilis) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 LEU A 373
LEU A 361
SER A 352
THR A 354
 None
 0.66A 5bojB-4tr6A:
undetectable		 5bojB-4tr6A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v1r ALPHA-1,6-MANNANASE

(Bacteroides
thetaiotaomicron) 		PF03663
(Glyco_hydro_76) 		4 THR A 202
ALA A 206
LEU A 210
SER A 211
 None
 1.00A 5bojB-4v1rA:
undetectable		 5bojB-4v1rA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v23 MATRIX PROTEIN

(Respiratory
syncytial virus) 		PF03393
(Pneumo_matrix) 		4 THR A  15
ALA A  17
SER A 116
THR A 118
 None
 0.74A 5bojB-4v23A:
undetectable		 5bojB-4v23A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zr8 UROPORPHYRINOGEN
DECARBOXYLASE

(Acinetobacter
baumannii) 		PF01208
(URO-D) 		4 LEU A 292
THR A  21
ALA A 326
LEU A 328
 None
 0.96A 5bojB-4zr8A:
undetectable		 5bojB-4zr8A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ztu DNA POLYMERASE
SUBUNIT GAMMA-2,
MITOCHONDRIAL

(Homo sapiens) 		PF03129
(HGTP_anticodon) 		4 LEU B 347
THR B 235
LEU B  91
SER B  90
 None
 0.98A 5bojB-4ztuB:
undetectable		 5bojB-4ztuB:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zv9 UNCHARACTERIZED
PROTEIN

(Escherichia
coli) 		PF01738
(DLH) 		4 LYS A  90
LEU A  88
THR A  98
LEU A 129
 None
 1.04A 5bojB-4zv9A:
undetectable		 5bojB-4zv9A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM

(Escherichia
coli) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF11974
(MG1) 		4 LEU A 850
THR A 827
LEU A 823
SER A 791
 None
 0.84A 5bojB-5a42A:
3.0		 5bojB-5a42A:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b7n MTA/SAH NUCLEOSIDASE

(Aeromonas
hydrophila) 		PF01048
(PNP_UDP_1) 		4 LEU A  80
THR A  87
ALA A  83
THR A  76
 None
 0.96A 5bojB-5b7nA:
undetectable		 5bojB-5b7nA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c53 POL GAMMA B

(Homo sapiens) 		PF03129
(HGTP_anticodon) 		4 LEU B 347
THR B 235
LEU B  91
SER B  90
 None
 1.01A 5bojB-5c53B:
undetectable		 5bojB-5c53B:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ere EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Desulfohalobium
retbaense) 		PF13458
(Peripla_BP_6) 		4 LEU A 511
THR A 591
ALA A 589
SER A 578
 None
 0.65A 5bojB-5ereA:
undetectable		 5bojB-5ereA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fd2 SERINE/THREONINE-PRO
TEIN KINASE B-RAF

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LYS A 483
LEU A 485
THR A 529
LEU A 525
 5XJ  A 801 (-3.8A)
None
5XJ  A 801 (-3.4A)
None
 0.86A 5bojB-5fd2A:
undetectable		 5bojB-5fd2A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ggy IRON(III) ABC
TRANSPORTER,
PERIPLASMIC
IRON-COMPOUND-BINDIN
G PROTEIN

(Vibrio cholerae) 		PF01497
(Peripla_BP_2) 		4 THR A 309
ALA A 305
LEU A 301
SER A 300
 None
 0.96A 5bojB-5ggyA:
undetectable		 5bojB-5ggyA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h9k LIPOCALIN AI-4

(Rhodnius
prolixus) 		PF03973
(Triabin) 		4 LEU A 108
LEU A 124
SER A  36
THR A  34
 None
 0.96A 5bojB-5h9kA:
undetectable		 5bojB-5h9kA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hm5 TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24)
PF14520
(HHH_5) 		4 LEU A 207
THR A 198
LEU A 209
SER A 210
 None
 0.92A 5bojB-5hm5A:
undetectable		 5bojB-5hm5A:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hpi P-HYDROXYBENZOATE
HYDROXYLASE
TRANSCRIPTIONAL
ACTIVATOR

(Acinetobacter
sp. ADP1) 		PF01614
(IclR) 		4 LEU A 260
ALA A 224
LEU A 238
THR A 161
 None
None
None
3HB  A 301 (-3.6A)
 1.02A 5bojB-5hpiA:
undetectable		 5bojB-5hpiA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5khn RND TRANSPORTER

(Burkholderia
multivorans) 		no annotation 4 LEU B 841
THR B 848
ALA B 844
THR B 759
 None
 0.87A 5bojB-5khnB:
undetectable		 5bojB-5khnB:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kis RHS2

(Yersinia
entomophaga) 		no annotation 4 LEU B 165
ALA B 161
LEU B 167
THR B 159
 None
 1.02A 5bojB-5kisB:
undetectable		 5bojB-5kisB:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lq4 CYAGOX

(Cyanothece sp.
PCC 7425) 		PF00881
(Nitroreductase) 		4 THR A 381
ALA A 377
LEU A 373
SER A 372
 FMN  A 901 (-4.6A)
None
None
None
 1.05A 5bojB-5lq4A:
undetectable		 5bojB-5lq4A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mq6 PYRIDINE
NUCLEOTIDE-DISULFIDE
OXIDOREDUCTASE-LIKE
PROTEIN

(Thermothelomyces
thermophila) 		PF07992
(Pyr_redox_2) 		4 LEU A 197
ALA A 216
LEU A 214
SER A  77
 None
 0.64A 5bojB-5mq6A:
undetectable		 5bojB-5mq6A:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzs FERRIC ENTEROBACTIN
RECEPTOR

(Pseudomonas
aeruginosa) 		no annotation 4 LEU A 342
THR A 370
LEU A 374
SER A 402
 None
 0.67A 5bojB-5mzsA:
undetectable		 5bojB-5mzsA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4a INTRAFLAGELLAR
TRANSPORT PROTEIN 80

(Chlamydomonas
reinhardtii) 		no annotation 4 THR A 428
ALA A 430
LEU A 432
THR A 423
 None
 0.55A 5bojB-5n4aA:
undetectable		 5bojB-5n4aA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o60 50S RIBOSOMAL
PROTEIN L10

(Mycolicibacterium
smegmatis) 		PF00466
(Ribosomal_L10) 		4 LEU I  56
THR I  50
ALA I  52
THR I  77
 None
 0.99A 5bojB-5o60I:
undetectable		 5bojB-5o60I:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo sapiens) 		no annotation 4 LEU B 147
THR B 124
LEU B 128
THR B 119
 None
 0.78A 5bojB-5ofbB:
undetectable		 5bojB-5ofbB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opt RIBOSOMAL PROTEIN
S25, PUTATIVE

(Trypanosoma
cruzi) 		no annotation 4 LYS a  84
LEU a  81
ALA a  83
SER a  72
 A  E2065 ( 3.4A)
None
None
None
 0.88A 5bojB-5opta:
undetectable		 5bojB-5opta:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5te6 LIGHT CHAIN OF N6

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.97A 5bojB-5te6L:
undetectable		 5bojB-5te6L:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tj6 HIGH CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL

(Aplysia
californica) 		PF00520
(Ion_trans)
PF03493
(BK_channel_a) 		4 THR A 853
ALA A 851
LEU A 847
SER A 846
 None
 1.04A 5bojB-5tj6A:
undetectable		 5bojB-5tj6A:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v3n MONOPOLIN COMPLEX
SUBUNIT CSM1

(Saccharomyces
cerevisiae) 		PF12539
(Csm1) 		4 LYS A 119
ALA A 135
SER A 162
THR A 160
 None
 0.90A 5bojB-5v3nA:
undetectable		 5bojB-5v3nA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vfr 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT
11

(Homo sapiens) 		no annotation 4 THR X 422
ALA X 418
LEU X 414
SER X 413
 None
 0.90A 5bojB-5vfrX:
undetectable		 5bojB-5vfrX:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yax SCFV1 ANTIBODY

(Homo sapiens) 		no annotation 4 THR A1092
ALA A1090
SER A1022
THR A1020
 None
 0.95A 5bojB-5yaxA:
undetectable		 5bojB-5yaxA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yp3 DIPEPTIDYL
AMINOPEPTIDASE 4

(Pseudoxanthomonas
mexicana) 		no annotation 4 LEU A 377
THR A 373
LEU A 364
SER A 355
 None
 0.85A 5bojB-5yp3A:
undetectable		 5bojB-5yp3A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c6y JC57-14 LIGHT CHAIN

(Macaca mulatta) 		no annotation 4 LEU B 135
THR B 172
SER B 162
THR B 164
 None
 0.85A 5bojB-6c6yB:
undetectable		 5bojB-6c6yB:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f3d INTERLEUKIN-1
RECEPTOR-ASSOCIATED
KINASE 4

(Homo sapiens) 		no annotation 4 LYS A 213
LEU A 215
LEU A 258
SER A 253
 CJT  A 502 (-3.0A)
None
None
None
 1.02A 5bojB-6f3dA:
undetectable		 5bojB-6f3dA:
16.54