SIMILAR PATTERNS OF AMINO ACIDS FOR 5BMV_C_VLBC507_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bja TRANSCRIPTION
REGULATORY PROTEIN
MOTA

(Escherichia
virus T4) 		PF09114
(MotA_activ) 		4 VAL A  49
ASN A  50
ILE A  53
VAL A  37
 None
 0.72A 5bmvC-1bjaA:
undetectable		 5bmvC-1bjaA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bu8 PROTEIN (PANCREATIC
LIPASE RELATED
PROTEIN 2)

(Rattus
norvegicus) 		PF00151
(Lipase)
PF01477
(PLAT) 		4 VAL A 124
ILE A 128
PHE A  72
VAL A  74
 None
 0.67A 5bmvC-1bu8A:
undetectable		 5bmvC-1bu8A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bu8 PROTEIN (PANCREATIC
LIPASE RELATED
PROTEIN 2)

(Rattus
norvegicus) 		PF00151
(Lipase)
PF01477
(PLAT) 		4 VAL A 124
ILE A 128
PHE A  72
VAL A 104
 None
 0.77A 5bmvC-1bu8A:
undetectable		 5bmvC-1bu8A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dcu FRUCTOSE-1,6-BISPHOS
PHATASE

(Pisum sativum) 		PF00316
(FBPase) 		4 VAL A  41
ILE A  45
PHE A 125
VAL A 123
 None
 0.78A 5bmvC-1dcuA:
undetectable		 5bmvC-1dcuA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dg4 DNAK

(Escherichia
coli) 		PF00012
(HSP70) 		4 VAL A 474
ILE A 472
VAL A 436
ILE A 438
 None
 0.80A 5bmvC-1dg4A:
undetectable		 5bmvC-1dg4A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dl5 PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Thermotoga
maritima) 		PF01135
(PCMT) 		5 VAL A 154
ASN A 176
ILE A 175
PHE A 186
ILE A  82
 None
 1.33A 5bmvC-1dl5A:
undetectable		 5bmvC-1dl5A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dl5 PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Thermotoga
maritima) 		PF01135
(PCMT) 		5 VAL A 154
ASN A 176
PHE A 186
VAL A 173
ILE A  82
 None
 1.40A 5bmvC-1dl5A:
undetectable		 5bmvC-1dl5A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1goj KINESIN HEAVY CHAIN

(Neurospora
crassa) 		PF00225
(Kinesin) 		4 VAL A 111
ILE A 115
VAL A  84
ILE A 304
 None
 0.75A 5bmvC-1gojA:
undetectable		 5bmvC-1gojA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gqr ACETYLCHOLINESTERASE

(Tetronarce
californica) 		PF00135
(COesterase) 		5 VAL A 113
ILE A 196
PHE A 219
VAL A 194
ILE A 184
 None
 1.39A 5bmvC-1gqrA:
undetectable		 5bmvC-1gqrA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gxh COLICIN E8 IMMUNITY
PROTEIN

(Escherichia
coli) 		PF01320
(Colicin_Pyocin) 		4 PRO A  63
VAL A  66
ILE A  70
ILE A  23
 None
 0.79A 5bmvC-1gxhA:
undetectable		 5bmvC-1gxhA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h32 CYTOCHROME C

(Rhodovulum
sulfidophilum) 		PF00034
(Cytochrom_C) 		4 PRO B   5
VAL B   8
ILE B  10
VAL B  81
 None
 0.68A 5bmvC-1h32B:
undetectable		 5bmvC-1h32B:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hcy ARTHROPODAN
HEMOCYANIN

(Panulirus
interruptus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 VAL A 416
ILE A 464
PHE A 478
VAL A 584
 None
 0.60A 5bmvC-1hcyA:
undetectable		 5bmvC-1hcyA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E SMALL SUBUNIT

(Galdieria
partita) 		PF00101
(RuBisCO_small) 		4 PRO B  80
VAL B  83
ILE B  87
ILE B  34
 None
 0.78A 5bmvC-1iwaB:
undetectable		 5bmvC-1iwaB:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j32 ASPARTATE
AMINOTRANSFERASE

(Phormidium
lapideum) 		PF00155
(Aminotran_1_2) 		5 PRO A 128
VAL A 131
ILE A 111
VAL A 117
ILE A 119
 None
 1.47A 5bmvC-1j32A:
2.5		 5bmvC-1j32A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jn5 TAP

(Homo sapiens) 		PF02136
(NTF2) 		4 VAL B 387
PHE B 479
VAL B 481
ILE B 483
 None
 0.59A 5bmvC-1jn5B:
undetectable		 5bmvC-1jn5B:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k5c ENDOPOLYGALACTURONAS
E

(Chondrostereum
purpureum) 		PF00295
(Glyco_hydro_28) 		4 VAL A 162
ILE A 164
PHE A 155
VAL A 124
 None
 0.73A 5bmvC-1k5cA:
undetectable		 5bmvC-1k5cA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k5c ENDOPOLYGALACTURONAS
E

(Chondrostereum
purpureum) 		PF00295
(Glyco_hydro_28) 		4 VAL A 162
ILE A 164
PHE A 155
VAL A 157
 None
 0.66A 5bmvC-1k5cA:
undetectable		 5bmvC-1k5cA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m0w GLUTATHIONE
SYNTHETASE

(Saccharomyces
cerevisiae) 		PF03199
(GSH_synthase)
PF03917
(GSH_synth_ATP) 		4 VAL A  18
ASN A  19
VAL A  46
ILE A  48
 None
 0.65A 5bmvC-1m0wA:
undetectable		 5bmvC-1m0wA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n26 IL-6 RECEPTOR ALPHA
CHAIN

(Homo sapiens) 		PF00047
(ig)
PF09240
(IL6Ra-bind) 		4 VAL A 217
ILE A 260
VAL A 271
ILE A 203
 None
 0.80A 5bmvC-1n26A:
undetectable		 5bmvC-1n26A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qfh PROTEIN (GELATION
FACTOR)

(Dictyostelium
discoideum) 		PF00630
(Filamin) 		5 VAL A 717
ILE A 674
PHE A 691
VAL A 693
ILE A 695
 None
 1.37A 5bmvC-1qfhA:
undetectable		 5bmvC-1qfhA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rgy BETA-LACTAMASE

(Citrobacter
freundii) 		PF00144
(Beta-lactamase) 		4 VAL A  12
ASN A  13
ILE A  16
VAL A  30
 None
 0.78A 5bmvC-1rgyA:
undetectable		 5bmvC-1rgyA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sky F1-ATPASE

(Bacillus sp.
PS3) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		5 PRO B 331
VAL B 334
ASN B 333
ILE B 337
ILE B 168
 None
 1.45A 5bmvC-1skyB:
3.0		 5bmvC-1skyB:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1spi FRUCTOSE
1,6-BISPHOSPHATASE

(Spinacia
oleracea) 		PF00316
(FBPase) 		4 VAL A  43
ILE A  47
PHE A 127
VAL A 125
 None
 0.73A 5bmvC-1spiA:
undetectable		 5bmvC-1spiA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1thg LIPASE 2

(Galactomyces
candidus) 		PF00135
(COesterase) 		5 VAL A 126
ILE A 213
PHE A 242
VAL A 211
ILE A 201
 None
 1.43A 5bmvC-1thgA:
2.4		 5bmvC-1thgA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2h AORTIC
PREFERENTIALLY
EXPRESSED PROTEIN 1

(Homo sapiens) 		PF07679
(I-set) 		4 PRO A  20
VAL A  43
ILE A  41
VAL A  51
 None
 0.67A 5bmvC-1u2hA:
undetectable		 5bmvC-1u2hA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ulv GLUCODEXTRANASE

(Arthrobacter
globiformis) 		PF00723
(Glyco_hydro_15)
PF09136
(Glucodextran_B)
PF09137
(Glucodextran_N)
PF09985
(Glucodextran_C) 		4 VAL A 928
ILE A 846
PHE A 822
VAL A 811
 None
 0.59A 5bmvC-1ulvA:
undetectable		 5bmvC-1ulvA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5b 3-ISOPROPYLMALATE
DEHYDROGENASE

(Bacillus
coagulans) 		PF00180
(Iso_dh) 		4 PRO A  15
ILE A  22
PHE A  38
VAL A   7
 None
 0.78A 5bmvC-1v5bA:
undetectable		 5bmvC-1v5bA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vhe AMINOPEPTIDASE/GLUCA
NASE HOMOLOG

(Bacillus
subtilis) 		PF05343
(Peptidase_M42) 		4 ILE A 343
PHE A 234
VAL A 236
ILE A 185
 None
 0.72A 5bmvC-1vheA:
3.7		 5bmvC-1vheA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE

(Saccharomyces
cerevisiae) 		PF00171
(Aldedh) 		4 VAL A 162
ASN A 163
ILE A 166
ILE A 129
 None
 0.54A 5bmvC-1vluA:
undetectable		 5bmvC-1vluA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vma CELL DIVISION
PROTEIN FTSY

(Thermotoga
maritima) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 VAL A  94
ILE A 180
VAL A 203
ILE A 207
 None
 0.76A 5bmvC-1vmaA:
4.1		 5bmvC-1vmaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vqt OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Thermotoga
maritima) 		PF00215
(OMPdecase) 		4 VAL A  62
ILE A  66
PHE A  77
VAL A  79
 None
 0.79A 5bmvC-1vqtA:
undetectable		 5bmvC-1vqtA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vsq MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT

(Escherichia
coli) 		PF03830
(PTSIIB_sorb) 		4 PRO C 247
VAL C 250
VAL C 263
ILE C 169
 None
 0.67A 5bmvC-1vsqC:
3.1		 5bmvC-1vsqC:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wlh GELATION FACTOR

(Dictyostelium
discoideum) 		PF00630
(Filamin) 		5 VAL A 615
ILE A 574
PHE A 591
VAL A 593
ILE A 595
 None
 1.45A 5bmvC-1wlhA:
undetectable		 5bmvC-1wlhA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wy1 HYPOTHETICAL PROTEIN
PH0671

(Pyrococcus
horikoshii) 		PF01923
(Cob_adeno_trans) 		4 ASN A  31
ILE A  27
PHE A 136
ILE A  76
 None
 0.70A 5bmvC-1wy1A:
undetectable		 5bmvC-1wy1A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xrc S-ADENOSYLMETHIONINE
SYNTHETASE

(Escherichia
coli) 		PF00438
(S-AdoMet_synt_N)
PF02772
(S-AdoMet_synt_M)
PF02773
(S-AdoMet_synt_C) 		4 VAL A  52
ILE A  95
VAL A  26
ILE A  22
 None
 0.80A 5bmvC-1xrcA:
undetectable		 5bmvC-1xrcA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yxm PEROXISOMAL TRANS
2-ENOYL COA
REDUCTASE

(Homo sapiens) 		PF13561
(adh_short_C2) 		4 VAL A 243
PHE A 103
VAL A 105
ILE A 157
 None
 0.80A 5bmvC-1yxmA:
7.2		 5bmvC-1yxmA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zcl PROTEIN TYROSINE
PHOSPHATASE 4A1

(Rattus
norvegicus) 		PF00782
(DSPc) 		4 PRO A 112
VAL A 115
VAL A  12
ILE A  21
 None
 0.64A 5bmvC-1zclA:
undetectable		 5bmvC-1zclA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zpv ACT DOMAIN PROTEIN

(Streptococcus
pneumoniae) 		PF13740
(ACT_6) 		4 VAL A   7
ILE A   5
VAL A  19
ILE A  15
 None
 0.80A 5bmvC-1zpvA:
undetectable		 5bmvC-1zpvA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zpv ACT DOMAIN PROTEIN

(Streptococcus
pneumoniae) 		PF13740
(ACT_6) 		4 VAL A  19
ILE A  15
VAL A   7
ILE A   5
 None
 0.69A 5bmvC-1zpvA:
undetectable		 5bmvC-1zpvA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zun SULFATE
ADENYLYLTRANSFERASE
SUBUNIT 2

(Pseudomonas
syringae) 		PF01507
(PAPS_reduct) 		5 PRO A 184
VAL A 182
ILE A 180
VAL A  22
ILE A  19
 None
 1.38A 5bmvC-1zunA:
undetectable		 5bmvC-1zunA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ak3 ADENYLATE KINASE
ISOENZYME-3

(Bos taurus) 		PF00406
(ADK)
PF05191
(ADK_lid) 		4 VAL A  21
ILE A  25
VAL A 206
ILE A 202
 None
 0.78A 5bmvC-2ak3A:
4.3		 5bmvC-2ak3A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ash QUEUINE
TRNA-RIBOSYLTRANSFER
ASE

(Thermotoga
maritima) 		PF01702
(TGT) 		4 VAL A 342
ILE A 346
VAL A 253
ILE A 249
 None
 0.78A 5bmvC-2ashA:
undetectable		 5bmvC-2ashA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b67 COG0778:
NITROREDUCTASE

(Streptococcus
pneumoniae) 		PF00881
(Nitroreductase) 		5 PRO A  23
VAL A  26
ILE A  30
PHE A  47
VAL A  49
 None
 0.59A 5bmvC-2b67A:
undetectable		 5bmvC-2b67A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bku IMPORTIN BETA-1
SUBUNIT

(Saccharomyces
cerevisiae) 		PF03810
(IBN_N)
PF13513
(HEAT_EZ) 		4 PRO B 497
VAL B 500
ILE B 504
PHE B 545
 None
 0.72A 5bmvC-2bkuB:
undetectable		 5bmvC-2bkuB:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bmf RNA HELICASE

(Dengue virus) 		PF07652
(Flavi_DEAD) 		5 PRO A 239
VAL A 257
ILE A 220
VAL A 208
ILE A 212
 None
 1.31A 5bmvC-2bmfA:
undetectable		 5bmvC-2bmfA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bv5 TYROSINE-PROTEIN
PHOSPHATASE,
NON-RECEPTOR TYPE 5

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 VAL A 454
PHE A 432
VAL A 372
ILE A 468
 None
 0.74A 5bmvC-2bv5A:
undetectable		 5bmvC-2bv5A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1i PEPTIDOGLYCAN GLCNAC
DEACETYLASE

(Streptococcus
pneumoniae) 		PF01522
(Polysacc_deac_1) 		4 VAL A 313
ILE A 316
PHE A 299
VAL A 301
 None
 0.71A 5bmvC-2c1iA:
undetectable		 5bmvC-2c1iA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2drh 361AA LONG
HYPOTHETICAL
D-AMINOPEPTIDASE

(Pyrococcus
horikoshii) 		PF03576
(Peptidase_S58) 		5 PRO A  80
ILE A  96
PHE A 284
VAL A 282
ILE A 280
 None
 1.09A 5bmvC-2drhA:
undetectable		 5bmvC-2drhA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f2a GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Staphylococcus
aureus) 		PF01425
(Amidase) 		4 PRO A  22
VAL A  25
ILE A  29
ILE A  15
 None
 0.74A 5bmvC-2f2aA:
undetectable		 5bmvC-2f2aA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fhx SPM-1

(Pseudomonas
aeruginosa) 		PF00753
(Lactamase_B) 		4 PRO B 297
VAL B 300
ASN B 301
ILE B 304
 None
 0.71A 5bmvC-2fhxB:
undetectable		 5bmvC-2fhxB:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fnu AMINOTRANSFERASE

(Helicobacter
pylori) 		PF01041
(DegT_DnrJ_EryC1) 		4 PRO A 348
ILE A 288
VAL A 365
ILE A 361
 None
 0.79A 5bmvC-2fnuA:
undetectable		 5bmvC-2fnuA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gwo DUAL SPECIFICITY
PROTEIN PHOSPHATASE
13

(Homo sapiens) 		PF00782
(DSPc) 		4 VAL A 119
ILE A 123
VAL A  76
ILE A 102
 None
 0.72A 5bmvC-2gwoA:
undetectable		 5bmvC-2gwoA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h7w CHAGASIN

(Trypanosoma
cruzi) 		PF09394
(Inhibitor_I42) 		4 VAL A  75
ILE A  24
PHE A 103
VAL A  85
 None
 0.78A 5bmvC-2h7wA:
undetectable		 5bmvC-2h7wA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hig 6-PHOSPHO-1-FRUCTOKI
NASE

(Trypanosoma
brucei) 		PF00365
(PFK) 		4 VAL A 115
ILE A 119
PHE A 194
VAL A 196
 None
 0.77A 5bmvC-2higA:
undetectable		 5bmvC-2higA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iex DIHYDROXYNAPTHOIC
ACID SYNTHETASE

(Geobacillus
kaustophilus) 		PF00378
(ECH_1) 		4 PRO A  38
VAL A  41
ASN A  42
ILE A  45
 None
 0.43A 5bmvC-2iexA:
undetectable		 5bmvC-2iexA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iq7 ENDOPOLYGALACTURONAS
E

(Colletotrichum
lupini) 		PF00295
(Glyco_hydro_28) 		4 VAL A 188
ILE A 190
PHE A 180
VAL A 182
 None
 0.79A 5bmvC-2iq7A:
undetectable		 5bmvC-2iq7A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3e T7I23.11 PROTEIN

(Arabidopsis
thaliana) 		PF04548
(AIG1) 		4 VAL A  53
ASN A  54
ILE A  57
VAL A  77
 None
 0.77A 5bmvC-2j3eA:
4.1		 5bmvC-2j3eA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mbg RALA-BINDING PROTEIN
1

(Homo sapiens) 		PF00620
(RhoGAP) 		5 PRO A 260
VAL A 220
ILE A 217
PHE A 213
ILE A 230
 None
 1.48A 5bmvC-2mbgA:
undetectable		 5bmvC-2mbgA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4z METAL-DEPENDENT
HYDROLASES OF THE
BETA-LACTAMASE
SUPERFAMILY II

(Caldanaerobacter
subterraneus) 		PF00753
(Lactamase_B) 		4 VAL A  47
ILE A  45
PHE A 146
VAL A 184
 None
 0.66A 5bmvC-2p4zA:
undetectable		 5bmvC-2p4zA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2paa PHOSPHOGLYCERATE
KINASE, TESTIS
SPECIFIC

(Mus musculus) 		PF00162
(PGK) 		5 PRO A 282
ASN A 323
ILE A 326
PHE A 232
VAL A 280
 None
 1.37A 5bmvC-2paaA:
undetectable		 5bmvC-2paaA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ph7 UNCHARACTERIZED
PROTEIN AF_2093

(Archaeoglobus
fulgidus) 		no annotation 5 PRO A 203
VAL A 201
PHE A 118
VAL A 114
ILE A 110
 None
 1.42A 5bmvC-2ph7A:
undetectable		 5bmvC-2ph7A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pok PEPTIDASE,
M20/M25/M40 FAMILY

(Streptococcus
pneumoniae) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 PRO A 341
VAL A 344
ILE A 348
VAL A 333
 None
 0.44A 5bmvC-2pokA:
undetectable		 5bmvC-2pokA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q4x SEED MATURATION
PROTEIN PM36 HOMOLOG

(Arabidopsis
thaliana) 		PF03070
(TENA_THI-4) 		5 PRO A 158
VAL A 159
PHE A  40
VAL A  28
ILE A  30
 None
 1.18A 5bmvC-2q4xA:
undetectable		 5bmvC-2q4xA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qlv CARBON CATABOLITE
DEREPRESSING PROTEIN
KINASE

(Saccharomyces
cerevisiae) 		PF16579
(AdenylateSensor) 		4 PRO A 515
VAL A 518
ILE A 522
VAL A 582
 None
 0.66A 5bmvC-2qlvA:
undetectable		 5bmvC-2qlvA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r6r CELL DIVISION
PROTEIN FTSZ

(Aquifex
aeolicus) 		PF00091
(Tubulin)
PF12327
(FtsZ_C) 		4 VAL 1 275
ILE 1 279
VAL 1 305
ILE 1 303
 None
 0.65A 5bmvC-2r6r1:
26.8		 5bmvC-2r6r1:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r6r CELL DIVISION
PROTEIN FTSZ

(Aquifex
aeolicus) 		PF00091
(Tubulin)
PF12327
(FtsZ_C) 		4 VAL 1 305
ILE 1 303
VAL 1 275
ILE 1 279
 None
 0.72A 5bmvC-2r6r1:
26.8		 5bmvC-2r6r1:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9v ATP SYNTHASE SUBUNIT
ALPHA

(Thermotoga
maritima) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		5 PRO A 332
VAL A 335
ASN A 334
ILE A 338
ILE A 169
 None
 1.47A 5bmvC-2r9vA:
undetectable		 5bmvC-2r9vA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rhq PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Staphylococcus
haemolyticus) 		PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		4 VAL B 420
ASN B 421
ILE B 424
VAL B 472
 None
 0.69A 5bmvC-2rhqB:
undetectable		 5bmvC-2rhqB:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vga PROTEIN A41

(Vaccinia virus) 		PF02250
(Orthopox_35kD) 		4 VAL A  18
ILE A  16
VAL A 106
ILE A 108
 None
 0.76A 5bmvC-2vgaA:
undetectable		 5bmvC-2vgaA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vtx NPM-A PROTEIN

(Xenopus laevis) 		PF03066
(Nucleoplasmin) 		4 VAL A  50
ILE A 113
PHE A 102
VAL A  63
 None
 0.71A 5bmvC-2vtxA:
undetectable		 5bmvC-2vtxA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w0m SSO2452

(Sulfolobus
solfataricus) 		PF06745
(ATPase) 		4 VAL A 110
ASN A 111
ILE A 114
VAL A 153
 None
 0.75A 5bmvC-2w0mA:
undetectable		 5bmvC-2w0mA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3j CARBOHYDRATE BINDING
MODULE

(uncultured
bacterium) 		PF16990
(CBM_35) 		4 VAL A  71
ILE A  78
VAL A  97
ILE A  57
 None
 0.64A 5bmvC-2w3jA:
undetectable		 5bmvC-2w3jA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3n CARBONIC ANHYDRASE 2

(Cryptococcus
neoformans) 		PF00484
(Pro_CA) 		4 VAL A 184
ILE A 190
VAL A 119
ILE A  66
 None
 0.74A 5bmvC-2w3nA:
undetectable		 5bmvC-2w3nA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wok CLAVULANIC ACID
BIOSYNTHESIS
OLIGOPEPTIDE BINDING
PROTEIN 2

(Streptomyces
clavuligerus) 		PF00496
(SBP_bac_5) 		4 VAL A 490
ASN A 491
ILE A 494
VAL A 468
 None
 0.78A 5bmvC-2wokA:
undetectable		 5bmvC-2wokA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xdq LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Thermosynechococcus
elongatus) 		PF00148
(Oxidored_nitro) 		5 PRO B 213
ASN B 167
ILE B 200
VAL B 143
ILE B 147
 None
 1.47A 5bmvC-2xdqB:
2.3		 5bmvC-2xdqB:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y5w KINESIN HEAVY CHAIN

(Drosophila
melanogaster) 		PF00225
(Kinesin) 		5 PRO A 116
VAL A 119
ASN A 120
VAL A 186
ILE A 190
 None
 1.35A 5bmvC-2y5wA:
undetectable		 5bmvC-2y5wA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE

(Bifidobacterium
longum) 		PF12905
(Glyco_hydro_101)
PF17451
(Glyco_hyd_101C) 		4 VAL A1233
PHE A1247
VAL A1250
ILE A1252
 None
 0.77A 5bmvC-2zxqA:
undetectable		 5bmvC-2zxqA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al0 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Thermotoga
maritima) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		5 PRO B 468
ASN B 472
ILE B 475
PHE B 454
VAL B 458
 C  E  56 ( 3.8A)
C  E  56 ( 4.0A)
None
None
None
 1.25A 5bmvC-3al0B:
undetectable		 5bmvC-3al0B:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3any ETHANOLAMINE
AMMONIA-LYASE HEAVY
CHAIN

(Escherichia
coli) 		PF06751
(EutB) 		5 VAL A 323
ASN A 324
ILE A 322
PHE A 321
ILE A 248
 None
2A3  A 602 ( 4.9A)
None
None
None
 1.41A 5bmvC-3anyA:
undetectable		 5bmvC-3anyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cvw RE11660P

(Drosophila
melanogaster) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		4 PRO A  89
VAL A  92
ILE A  96
VAL A  85
 None
 0.78A 5bmvC-3cvwA:
undetectable		 5bmvC-3cvwA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3czc RMPB

(Streptococcus
mutans) 		PF02302
(PTS_IIB) 		4 VAL A  55
ILE A  53
VAL A  22
ILE A  18
 None
 0.80A 5bmvC-3czcA:
undetectable		 5bmvC-3czcA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dob HEAT SHOCK 70 KDA
PROTEIN F44E5.5

(Caenorhabditis
elegans) 		PF00012
(HSP70) 		4 VAL A 443
ILE A 404
VAL A 489
ILE A 504
 None
 0.71A 5bmvC-3dobA:
undetectable		 5bmvC-3dobA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e48 PUTATIVE
NUCLEOSIDE-DIPHOSPHA
TE-SUGAR EPIMERASE

(Staphylococcus
aureus) 		PF13460
(NAD_binding_10) 		4 VAL A 181
ILE A 185
VAL A  70
ILE A 104
 None
 0.73A 5bmvC-3e48A:
2.1		 5bmvC-3e48A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eo4 UNCHARACTERIZED
PROTEIN MJ1062

(Methanocaldococcus
jannaschii) 		PF13302
(Acetyltransf_3) 		5 VAL A 419
ASN A 420
ILE A 431
VAL A 453
ILE A 354
 None
MES  A   8 (-3.4A)
None
None
None
 1.46A 5bmvC-3eo4A:
undetectable		 5bmvC-3eo4A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fyf PROTEIN BVU-3222

(Bacteroides
vulgatus) 		PF14059
(DUF4251) 		4 VAL A  90
ILE A  99
VAL A 152
ILE A 154
 None
 0.69A 5bmvC-3fyfA:
undetectable		 5bmvC-3fyfA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0x 78 KDA
GLUCOSE-REGULATED
PROTEIN HOMOLOG

(Saccharomyces
cerevisiae) 		PF00012
(HSP70) 		4 VAL A 485
ILE A 446
VAL A 531
ILE A 546
 None
 0.66A 5bmvC-3h0xA:
undetectable		 5bmvC-3h0xA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hl0 MALEYLACETATE
REDUCTASE

(Agrobacterium
fabrum) 		PF00465
(Fe-ADH) 		4 VAL A  23
ILE A  27
VAL A  90
ILE A 115
 None
 0.73A 5bmvC-3hl0A:
2.7		 5bmvC-3hl0A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ift GLYCINE CLEAVAGE
SYSTEM H PROTEIN

(Mycobacterium
tuberculosis) 		PF01597
(GCV_H) 		4 PRO A  89
VAL A  92
ASN A  93
VAL A  61
 None
 0.77A 5bmvC-3iftA:
undetectable		 5bmvC-3iftA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iwk AMINOALDEHYDE
DEHYDROGENASE

(Pisum sativum) 		PF00171
(Aldedh) 		4 VAL A 345
ILE A 349
VAL A 375
ILE A 336
 None
 0.80A 5bmvC-3iwkA:
undetectable		 5bmvC-3iwkA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k4h PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Bacillus
cytotoxicus) 		PF13377
(Peripla_BP_3) 		5 VAL A  14
ILE A  73
PHE A  93
VAL A  61
ILE A  57
 None
 1.43A 5bmvC-3k4hA:
undetectable		 5bmvC-3k4hA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpp SUCRASE-ISOMALTASE

(Homo sapiens) 		PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N) 		4 ILE A 827
PHE A 842
VAL A 845
ILE A 847
 None
 0.77A 5bmvC-3lppA:
undetectable		 5bmvC-3lppA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lxu TRIPEPTIDYL-PEPTIDAS
E 2

(Drosophila
melanogaster) 		PF00082
(Peptidase_S8)
PF12580
(TPPII)
PF12583
(TPPII_N) 		4 VAL X 472
ILE X 476
VAL X 367
ILE X 394
 None
 0.78A 5bmvC-3lxuX:
undetectable		 5bmvC-3lxuX:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m05 UNCHARACTERIZED
PROTEIN PEPE_1480

(Pediococcus
pentosaceus) 		PF06153
(CdAMP_rec) 		4 VAL A  58
ILE A  62
VAL A   6
ILE A  50
 None
 0.76A 5bmvC-3m05A:
undetectable		 5bmvC-3m05A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mes CHOLINE KINASE

(Cryptosporidium
parvum) 		PF01633
(Choline_kinase) 		5 PRO A 103
ILE A 148
PHE A 107
VAL A  89
ILE A  91
 None
 1.20A 5bmvC-3mesA:
undetectable		 5bmvC-3mesA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n8e STRESS-70 PROTEIN,
MITOCHONDRIAL

(Homo sapiens) 		PF00012
(HSP70) 		4 VAL A 486
ILE A 447
VAL A 532
ILE A 547
 None
 0.67A 5bmvC-3n8eA:
undetectable		 5bmvC-3n8eA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n9i TRYPTOPHANYL-TRNA
SYNTHETASE

(Yersinia pestis) 		PF00579
(tRNA-synt_1b) 		4 PRO A 225
VAL A 228
ILE A 232
VAL A 293
 None
 0.71A 5bmvC-3n9iA:
undetectable		 5bmvC-3n9iA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nv0 NUCLEAR RNA EXPORT
FACTOR 2

(Caenorhabditis
elegans) 		no annotation 4 VAL A 216
ILE A 220
PHE A 320
VAL A 322
 None
 0.79A 5bmvC-3nv0A:
undetectable		 5bmvC-3nv0A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwn KINESIN-LIKE PROTEIN
KIF9

(Homo sapiens) 		PF00225
(Kinesin) 		4 VAL A 123
ILE A 127
VAL A 137
ILE A 222
 None
 0.73A 5bmvC-3nwnA:
undetectable		 5bmvC-3nwnA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)

(Corynebacterium
glutamicum) 		PF01370
(Epimerase)
PF08338
(DUF1731) 		4 PRO A 488
VAL A 491
ILE A 495
VAL A  93
 None
 0.57A 5bmvC-3oh8A:
4.8		 5bmvC-3oh8A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3orq N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
SYNTHETASE

(Staphylococcus
aureus) 		PF02222
(ATP-grasp)
PF02826
(2-Hacid_dh_C) 		4 VAL A 238
ASN A 239
ILE A 242
VAL A 196
 None
 0.66A 5bmvC-3orqA:
undetectable		 5bmvC-3orqA:
22.67