SIMILAR PATTERNS OF AMINO ACIDS FOR 5BMV_C_VLBC507_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP1)
PROTEIN (CRICKET
PARALYSIS VIRUS,
VP3)

(Cricket
paralysis virus) 		PF08762
(CRPV_capsid)
no annotation 		4 ASP A 197
TYR C 257
PRO A 253
TYR A  96
 None
 1.14A 5bmvB-1b35A:
undetectable		 5bmvB-1b35A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhq CD11B

(Homo sapiens) 		PF00092
(VWA) 		4 LYS 1 187
ASP 1 134
PRO 1 193
LEU 1 198
 None
 1.30A 5bmvB-1bhq1:
undetectable		 5bmvB-1bhq1:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ed3 CLASS I MAJOR
HISTOCOMPATIBILITY
ANTIGEN RT1-AA

(Rattus
norvegicus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 ASP A  77
TYR A  99
TYR A 152
LEU A 156
 None
 1.35A 5bmvB-1ed3A:
undetectable		 5bmvB-1ed3A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h76 SEROTRANSFERRIN

(Sus scrofa) 		PF00405
(Transferrin) 		4 ASP A 461
TYR A 655
TYR A 663
LEU A 659
 None
 1.32A 5bmvB-1h76A:
undetectable		 5bmvB-1h76A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i60 IOLI PROTEIN

(Bacillus
subtilis) 		PF01261
(AP_endonuc_2) 		4 ASP A  49
PRO A  40
TYR A  42
LEU A  16
 None
 1.36A 5bmvB-1i60A:
undetectable		 5bmvB-1i60A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1js4 ENDO/EXOCELLULASE E4

(Thermobifida
fusca) 		PF00759
(Glyco_hydro_9)
PF00942
(CBM_3) 		4 ASP A 419
TYR A 363
TYR A 429
LEU A 402
 None
 1.35A 5bmvB-1js4A:
undetectable		 5bmvB-1js4A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k1x 4-ALPHA-GLUCANOTRANS
FERASE

(Thermococcus
litoralis) 		PF03065
(Glyco_hydro_57)
PF09094
(DUF1925)
PF09095
(DUF1926) 		4 LYS A 622
ASP A 481
PRO A 367
TYR A 365
 None
 1.24A 5bmvB-1k1xA:
undetectable		 5bmvB-1k1xA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lla HEMOCYANIN (SUBUNIT
TYPE II)

(Limulus
polyphemus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 ASP A 578
PRO A 110
TYR A 107
LEU A 520
 NA  A 631 (-3.6A)
None
None
None
 1.28A 5bmvB-1llaA:
undetectable		 5bmvB-1llaA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mpx ALPHA-AMINO ACID
ESTER HYDROLASE

(Xanthomonas
citri) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C) 		4 ASP A 501
TYR A 420
PRO A 629
LEU A 421
 None
 1.35A 5bmvB-1mpxA:
3.3		 5bmvB-1mpxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE

(Synechocystis
sp.) 		PF00834
(Ribul_P_3_epim) 		4 LYS A  76
TYR A  77
PRO A  51
LEU A  69
 None
 1.30A 5bmvB-1tqjA:
undetectable		 5bmvB-1tqjA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u0x NITROPHORIN 4

(Rhodnius
prolixus) 		PF02087
(Nitrophorin) 		4 LYS A 162
ASP A  27
PRO A  33
LEU A  31
 None
 1.24A 5bmvB-1u0xA:
undetectable		 5bmvB-1u0xA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2v ACTIN-RELATED
PROTEIN 3
ARP2/3 COMPLEX 34KDA
SUBUNIT

(Bos taurus) 		PF00022
(Actin)
PF04045
(P34-Arc) 		4 LYS A  99
ASP D  37
TYR A 100
LEU A  19
 None
 1.34A 5bmvB-1u2vA:
undetectable		 5bmvB-1u2vA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		4 LYS A1083
TYR A1080
TYR A1065
LEU A1077
 None
 1.21A 5bmvB-2b39A:
undetectable		 5bmvB-2b39A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c6y FORKHEAD BOX PROTEIN
K2

(Homo sapiens) 		PF00250
(Forkhead) 		4 ASP A  44
PRO A   4
TYR A   8
LEU A  11
 None
 1.24A 5bmvB-2c6yA:
undetectable		 5bmvB-2c6yA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eaa 7S GLOBULIN-3

(Vigna angularis) 		PF00190
(Cupin_1) 		4 ASP A 306
PRO A 335
TYR A 322
LEU A 301
 None
 1.35A 5bmvB-2eaaA:
undetectable		 5bmvB-2eaaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gnp TRANSCRIPTIONAL
REGULATOR

(Streptococcus
pneumoniae) 		PF04198
(Sugar-bind) 		4 LYS A 310
ASP A 315
TYR A  67
LEU A  64
 None
None
PEG  A 319 ( 3.8A)
PEG  A 319 ( 4.9A)
 1.21A 5bmvB-2gnpA:
undetectable		 5bmvB-2gnpA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nvv ACETYL-COA
HYDROLASE/TRANSFERAS
E FAMILY PROTEIN

(Porphyromonas
gingivalis) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		4 ASP A 172
TYR A 188
TYR A 282
LEU A 345
 ASP  A 172 ( 0.6A)
TYR  A 188 ( 1.3A)
TYR  A 282 ( 1.3A)
LEU  A 345 ( 0.6A)
 1.08A 5bmvB-2nvvA:
undetectable		 5bmvB-2nvvA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME

(Bos taurus) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 LYS A 471
TYR A 472
TYR A 525
LEU A 364
 CLU  A 808 (-3.7A)
CLU  A 808 (-3.4A)
None
None
 1.27A 5bmvB-2pncA:
undetectable		 5bmvB-2pncA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vl8 CYTOTOXIN L

(Paeniclostridium
sordellii) 		PF12918
(TcdB_N)
PF12919
(TcdA_TcdB) 		4 LYS A 119
ASP A 124
PRO A 291
LEU A 285
 None
 1.35A 5bmvB-2vl8A:
undetectable		 5bmvB-2vl8A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpw THIOSULFATE
REDUCTASE

(Thermus
thermophilus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 ASP A 673
TYR A 723
PRO A 447
LEU A 734
 None
None
None
MGD  A1765 (-4.9A)
 1.37A 5bmvB-2vpwA:
2.9		 5bmvB-2vpwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w55 XANTHINE
DEHYDROGENASE

(Rhodobacter
capsulatus) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 TYR B 319
PRO B 452
TYR B 624
LEU B 414
 None
 1.16A 5bmvB-2w55B:
undetectable		 5bmvB-2w55B:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x0i MALATE DEHYDROGENASE

(Archaeoglobus
fulgidus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 LYS A 115
ASP A 122
TYR A 331
LEU A 329
 None
 1.34A 5bmvB-2x0iA:
4.4		 5bmvB-2x0iA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xvg ALPHA XYLOSIDASE

(Cellvibrio
japonicus) 		PF01055
(Glyco_hydro_31)
PF16338
(DUF4968)
PF17137
(DUF5110) 		4 TYR A 261
PRO A 292
TYR A 299
LEU A 304
 None
 1.37A 5bmvB-2xvgA:
undetectable		 5bmvB-2xvgA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y89 PHOSPHORIBOSYL
ISOMERASE A

(Mycobacterium
tuberculosis) 		PF00977
(His_biosynth) 		4 ASP A  36
PRO A   8
TYR A 230
LEU A 229
 None
 1.25A 5bmvB-2y89A:
undetectable		 5bmvB-2y89A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE

(Mus musculus) 		PF05889
(SepSecS) 		4 ASP A 171
PRO A 430
TYR A 433
LEU A 364
 None
 1.15A 5bmvB-3bc8A:
undetectable		 5bmvB-3bc8A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdi UNCHARACTERIZED
PROTEIN TA0194

(Thermoplasma
acidophilum) 		PF00561
(Abhydrolase_1)
PF12146
(Hydrolase_4) 		4 ASP A 141
TYR A 168
PRO A 132
LEU A 151
 None
 1.38A 5bmvB-3bdiA:
3.7		 5bmvB-3bdiA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c1o EUGENOL SYNTHASE

(Clarkia breweri) 		PF05368
(NmrA) 		4 ASP A 173
PRO A 242
TYR A 177
LEU A 246
 None
 1.13A 5bmvB-3c1oA:
6.2		 5bmvB-3c1oA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwk PENICILLIN-BINDING
PROTEIN 2

(Staphylococcus
aureus) 		PF00905
(Transpeptidase)
PF00912
(Transgly) 		4 ASP A 241
PRO A 231
TYR A 226
LEU A 227
 None
 1.32A 5bmvB-3dwkA:
undetectable		 5bmvB-3dwkA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)

(Streptococcus
pneumoniae) 		PF14506
(CppA_N)
PF14507
(CppA_C) 		4 LYS A  99
TYR A 104
PRO A 134
LEU A  88
 None
 0.98A 5bmvB-3e0rA:
undetectable		 5bmvB-3e0rA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f6t ASPARTATE
AMINOTRANSFERASE

(Lactobacillus
acidophilus) 		PF00155
(Aminotran_1_2) 		4 LYS A 329
ASP A 165
TYR A 302
TYR A 297
 None
 1.06A 5bmvB-3f6tA:
undetectable		 5bmvB-3f6tA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fky GLUTAMINE SYNTHETASE

(Saccharomyces
cerevisiae) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 ASP A  32
TYR A 342
PRO A 341
LEU A 343
 None
 1.28A 5bmvB-3fkyA:
undetectable		 5bmvB-3fkyA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fxg RHAMNONATE
DEHYDRATASE

(Fusarium
graminearum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ASP A 164
TYR A 331
PRO A 367
LEU A 379
 None
 1.34A 5bmvB-3fxgA:
undetectable		 5bmvB-3fxgA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT

(Vibrio
vulnificus) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF13588
(HSDR_N_2) 		4 ASP A 367
TYR A 110
TYR A 181
LEU A 114
 None
 0.83A 5bmvB-3h1tA:
undetectable		 5bmvB-3h1tA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06

(Sarcoptes
scabiei) 		PF00089
(Trypsin) 		4 ASP A 226
TYR A 219
TYR A  86
LEU A 215
 None
 1.37A 5bmvB-3h7tA:
undetectable		 5bmvB-3h7tA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hig AMILORIDE-SENSITIVE
AMINE OXIDASE

(Homo sapiens) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 LYS A 462
ASP A 466
TYR A 463
LEU A 378
 TPQ  A 461 ( 3.4A)
None
TPQ  A 461 ( 4.5A)
None
 1.32A 5bmvB-3higA:
undetectable		 5bmvB-3higA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ie1 RIBONUCLEASE
TTHA0252

(Thermus
thermophilus) 		PF00753
(Lactamase_B)
PF07521
(RMMBL)
PF10996
(Beta-Casp) 		4 ASP A  63
PRO A   5
TYR A 159
LEU A 184
 ZN  A 452 (-2.5A)
None
None
None
 1.29A 5bmvB-3ie1A:
undetectable		 5bmvB-3ie1A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iv0 SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ASP A 105
TYR A  89
TYR A  68
LEU A  90
 None
 1.25A 5bmvB-3iv0A:
1.5		 5bmvB-3iv0A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j3i CAPSID PROTEIN

(Penicillium
chrysogenum
virus) 		no annotation 4 ASP A 557
PRO A 308
TYR A 312
LEU A 212
 None
 0.83A 5bmvB-3j3iA:
undetectable		 5bmvB-3j3iA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jux PROTEIN TRANSLOCASE
SUBUNIT SECA

(Thermotoga
maritima) 		PF00271
(Helicase_C)
PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		4 LYS A 346
ASP A 350
TYR A 374
LEU A 378
 None
 1.23A 5bmvB-3juxA:
2.3		 5bmvB-3juxA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3keb PROBABLE THIOL
PEROXIDASE

(Chromobacterium
violaceum) 		no annotation 4 ASP A  58
PRO A 136
TYR A 133
LEU A 130
 None
 1.09A 5bmvB-3kebA:
undetectable		 5bmvB-3kebA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kk7 PUTATIVE CELL
INVASION PROTEIN
WITH MAC/PERFORIN
DOMAIN

(Bacteroides
thetaiotaomicron) 		PF01823
(MACPF) 		4 ASP A 423
TYR A 393
TYR A 530
LEU A 466
 None
 1.28A 5bmvB-3kk7A:
undetectable		 5bmvB-3kk7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kny HYPOTHETICAL PROTEIN
BT_3535

(Bacteroides
thetaiotaomicron) 		no annotation 4 LYS A 158
TYR A 156
PRO A 188
LEU A 213
 None
 1.22A 5bmvB-3knyA:
undetectable		 5bmvB-3knyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l40 BRCT-CONTAINING
PROTEIN 1

(Schizosaccharomyces
pombe) 		PF16770
(RTT107_BRCT_5) 		4 ASP A 819
TYR A 809
TYR A 778
LEU A 806
 None
 1.31A 5bmvB-3l40A:
undetectable		 5bmvB-3l40A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lcm PUTATIVE
OXIDOREDUCTASE

(Streptococcus
mutans) 		PF02525
(Flavodoxin_2) 		4 ASP A  97
PRO A 152
TYR A 106
LEU A 113
 None
None
NAP  A 198 (-4.2A)
None
 0.92A 5bmvB-3lcmA:
2.1		 5bmvB-3lcmA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mtr NEURAL CELL ADHESION
MOLECULE 1

(Homo sapiens) 		PF00041
(fn3)
PF07679
(I-set) 		4 ASP A 469
PRO A 446
TYR A 477
LEU A 464
 None
 1.32A 5bmvB-3mtrA:
undetectable		 5bmvB-3mtrA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mtt PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT BETA

(Homo sapiens) 		PF16454
(PI3K_P85_iSH2) 		4 LYS A 558
PRO A 565
TYR A 460
LEU A 563
 None
 1.34A 5bmvB-3mttA:
undetectable		 5bmvB-3mttA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzb NICKEL-BINDING
PERIPLASMIC PROTEIN

(Escherichia
coli) 		PF00496
(SBP_bac_5) 		4 ASP A 432
TYR A 451
PRO A 404
LEU A 455
 None
 1.36A 5bmvB-3mzbA:
undetectable		 5bmvB-3mzbA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nnm CURA

(Lyngbya
majuscula) 		PF05721
(PhyH) 		4 ASP A  59
TYR A 193
TYR A 266
LEU A 169
 None
 1.38A 5bmvB-3nnmA:
undetectable		 5bmvB-3nnmA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opb SWI5-DEPENDENT HO
EXPRESSION PROTEIN 4

(Saccharomyces
cerevisiae) 		PF11701
(UNC45-central) 		4 LYS A 535
ASP A 588
TYR A 536
LEU A 499
 None
 1.29A 5bmvB-3opbA:
undetectable		 5bmvB-3opbA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pfe SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE

(Legionella
pneumophila) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 ASP A  98
TYR A 132
TYR A  26
LEU A  23
 None
 1.21A 5bmvB-3pfeA:
3.8		 5bmvB-3pfeA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qvi HISTO-ASPARTIC
PROTEASE

(Plasmodium
falciparum) 		PF00026
(Asp) 		4 ASP A  67
TYR A  99
TYR A  56
LEU A  20
 ASP  A  67 ( 0.6A)
TYR  A  99 ( 1.3A)
TYR  A  56 ( 1.3A)
LEU  A  20 ( 0.5A)
 1.20A 5bmvB-3qviA:
undetectable		 5bmvB-3qviA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqe MALONYL-COA-[ACYL-CA
RRIER-PROTEIN]
TRANSACYLASE

(Coxiella
burnetii) 		PF00698
(Acyl_transf_1) 		4 ASP A 216
PRO A  65
TYR A  97
LEU A  94
 None
None
None
GLY  A 314 ( 4.6A)
 1.08A 5bmvB-3tqeA:
undetectable		 5bmvB-3tqeA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u8p CYTOCHROME B562
INTEGRAL FUSION WITH
ENHANCED GREEN
FLUORESCENT PROTEIN

(Aequorea
victoria;
Escherichia
coli) 		PF01353
(GFP)
PF07361
(Cytochrom_B562) 		4 LYS A 146
ASP A  36
TYR A 147
PRO A  87
 None
None
None
HEM  A 347 ( 4.9A)
 1.04A 5bmvB-3u8pA:
undetectable		 5bmvB-3u8pA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vh0 UNCHARACTERIZED
PROTEIN YNCE

(Escherichia
coli) 		no annotation 4 ASP A  66
TYR A  44
TYR A  72
LEU A  57
 None
 1.31A 5bmvB-3vh0A:
undetectable		 5bmvB-3vh0A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a6e HYDROXYINDOLE
O-METHYLTRANSFERASE

(Homo sapiens) 		PF00891
(Methyltransf_2)
PF16864
(Dimerisation2) 		4 LYS A  74
ASP A  65
PRO A  43
LEU A  37
 SO4  A1353 (-3.2A)
None
None
None
 1.28A 5bmvB-4a6eA:
undetectable		 5bmvB-4a6eA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ag6 TYPE IV SECRETORY
PATHWAY VIRB4
COMPONENTS-LIKE
PROTEIN

(Thermoanaerobacter
pseudethanolicus) 		PF01935
(DUF87) 		4 ASP A 511
TYR A 447
PRO A 273
LEU A 435
 None
 1.15A 5bmvB-4ag6A:
undetectable		 5bmvB-4ag6A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ak1 BT_4661

(Bacteroides
thetaiotaomicron) 		PF16319
(DUF4958) 		4 ASP A 341
TYR A 399
PRO A 371
LEU A 378
 None
 1.37A 5bmvB-4ak1A:
undetectable		 5bmvB-4ak1A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B

(Cellvibrio
japonicus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16338
(DUF4968)
PF17137
(DUF5110) 		4 ASP A 165
TYR A 201
TYR A 242
LEU A 245
 None
 1.32A 5bmvB-4b9yA:
undetectable		 5bmvB-4b9yA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cbw ACTIN, ALPHA
SKELETAL MUSCLE,
ACTIN

(Plasmodium
berghei;
synthetic
construct) 		PF00022
(Actin) 		4 LYS A 337
ASP A 155
TYR A 338
PRO A  28
 ATP  A1379 ( 3.8A)
CA  A1377 ( 4.3A)
None
None
 1.36A 5bmvB-4cbwA:
undetectable		 5bmvB-4cbwA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ecn LEUCINE-RICH REPEAT
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF14660
(DUF4458) 		4 LYS A 303
ASP A 298
PRO A 368
TYR A 504
 None
 1.36A 5bmvB-4ecnA:
undetectable		 5bmvB-4ecnA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eco UNCHARACTERIZED
PROTEIN

(Bacteroides
eggerthii) 		no annotation 4 LYS A 304
ASP A 299
PRO A 366
TYR A 502
 None
 1.24A 5bmvB-4ecoA:
undetectable		 5bmvB-4ecoA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4efh ACTIN-1

(Acanthamoeba
castellanii) 		PF00022
(Actin) 		4 LYS A 336
ASP A 154
TYR A 337
PRO A  27
 ADP  A 403 (-3.6A)
CA  A 401 ( 4.4A)
None
None
 1.38A 5bmvB-4efhA:
undetectable		 5bmvB-4efhA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f62 GERANYLTRANSTRANSFER
ASE

(Marinomonas sp.
MED121) 		PF00348
(polyprenyl_synt) 		4 LYS A 277
ASP A 283
TYR A 208
LEU A 205
 None
 1.37A 5bmvB-4f62A:
undetectable		 5bmvB-4f62A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gys ALLOPHANATE
HYDROLASE

(Granulibacter
bethesdensis) 		PF01425
(Amidase) 		4 ASP A 293
TYR A 393
PRO A 252
LEU A 365
 None
 0.91A 5bmvB-4gysA:
undetectable		 5bmvB-4gysA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hxe PUTATIVE
UNCHARACTERIZED
PROTEIN PH0594

(Pyrococcus
horikoshii) 		PF00326
(Peptidase_S9)
PF07676
(PD40) 		4 ASP B 329
TYR B 275
TYR B 314
LEU B 286
 None
 1.37A 5bmvB-4hxeB:
undetectable		 5bmvB-4hxeB:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4inz SOLUBLE EPOXIDE
HYDROLASE

(Bacillus
megaterium) 		PF00561
(Abhydrolase_1) 		4 ASP A  97
PRO A 172
TYR A 187
LEU A 179
 PEG  A 302 ( 4.7A)
None
None
None
 1.21A 5bmvB-4inzA:
2.8		 5bmvB-4inzA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jso OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		4 ASP A  33
PRO A 174
TYR A 187
LEU A 207
 CA  A 606 ( 3.4A)
None
None
None
 1.24A 5bmvB-4jsoA:
undetectable		 5bmvB-4jsoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pzl ADENYLATE KINASE

(Francisella
tularensis) 		PF00406
(ADK)
PF05191
(ADK_lid) 		4 ASP A 104
TYR A 182
PRO A  87
LEU A   6
 None
 0.97A 5bmvB-4pzlA:
3.6		 5bmvB-4pzlA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9z UNCHARACTERIZED
PROTEIN

(Mycobacterium
avium) 		PF13622
(4HBT_3) 		4 ASP A   7
PRO A 177
TYR A 194
LEU A 191
 None
 1.33A 5bmvB-4r9zA:
undetectable		 5bmvB-4r9zA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rz2 SITE-DETERMINING
PROTEIN

(Geobacillus
thermodenitrificans) 		PF10609
(ParA) 		4 LYS A  93
TYR A 101
TYR A 133
LEU A  55
 None
 1.38A 5bmvB-4rz2A:
5.1		 5bmvB-4rz2A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3t PENICILLIN-BINDING
PROTEIN 2

(Neisseria
gonorrhoeae) 		PF00905
(Transpeptidase) 		4 TYR A 422
PRO A 308
TYR A 383
LEU A 424
 None
 1.29A 5bmvB-4u3tA:
undetectable		 5bmvB-4u3tA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w5z CHITINASE 60

(Moritella
marina) 		PF00704
(Glyco_hydro_18) 		4 ASP A 151
TYR A 194
PRO A 193
LEU A 195
 ACT  A 404 (-2.7A)
None
None
None
 1.38A 5bmvB-4w5zA:
undetectable		 5bmvB-4w5zA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xb1 319AA LONG
HYPOTHETICAL
HOMOSERINE
DEHYDROGENASE

(Pyrococcus
horikoshii) 		PF00742
(Homoserine_dh)
PF03447
(NAD_binding_3) 		4 ASP A 307
TYR A 101
PRO A 118
TYR A 123
 None
None
None
MPD  A1004 ( 4.8A)
 1.33A 5bmvB-4xb1A:
undetectable		 5bmvB-4xb1A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yfj AMINOGLYCOSIDE
3'-N-ACETYLTRANSFERA
SE

(Pseudomonas
aeruginosa) 		PF00583
(Acetyltransf_1) 		4 ASP A 109
PRO A 151
TYR A 156
LEU A 155
 None
SO4  A 204 ( 4.6A)
None
SO4  A 201 ( 4.4A)
 1.05A 5bmvB-4yfjA:
undetectable		 5bmvB-4yfjA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z8n RETICULOCYTE-BINDING
PROTEIN 2A

(Plasmodium
vivax) 		no annotation 4 LYS A 192
TYR A 205
TYR A 410
LEU A 294
 None
 1.35A 5bmvB-4z8nA:
undetectable		 5bmvB-4z8nA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zdl O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE

(Homo sapiens) 		PF05889
(SepSecS) 		4 ASP A 171
PRO A 430
TYR A 433
LEU A 364
 None
 1.08A 5bmvB-4zdlA:
undetectable		 5bmvB-4zdlA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zkt BOTULINUM NEUROTOXIN
TYPE E,
NONTOXIC-NONHEMAGGLU
TININ COMPONENT,
NTNH

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07953
(Toxin_R_bind_N)
PF08470
(NTNH_C) 		4 ASP B 711
TYR B 318
TYR B 178
LEU B 322
 None
 1.11A 5bmvB-4zktB:
undetectable		 5bmvB-4zktB:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Burkholderia
vietnamiensis) 		PF02350
(Epimerase_2) 		4 ASP A 290
PRO A 255
TYR A 244
LEU A 260
 EDO  A 503 (-3.2A)
None
None
None
 1.30A 5bmvB-5dldA:
7.3		 5bmvB-5dldA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dqs ELONGATION FACTOR
1-GAMMA

(Homo sapiens) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 ASP A 143
PRO A 178
TYR A 172
LEU A 209
 None
 1.10A 5bmvB-5dqsA:
undetectable		 5bmvB-5dqsA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5epg ALDEHYDE OXIDASE

(Homo sapiens) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		4 TYR A 898
PRO A1011
TYR A1164
LEU A 973
 None
 1.29A 5bmvB-5epgA:
undetectable		 5bmvB-5epgA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gk2 KETOSYNTHASE STLD

(Photorhabdus
laumondii) 		PF08541
(ACP_syn_III_C) 		4 LYS A  49
TYR A  50
PRO A  18
TYR A  53
 None
 1.37A 5bmvB-5gk2A:
undetectable		 5bmvB-5gk2A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gy0 GLUCANASE

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9)
PF00942
(CBM_3) 		4 ASP A 430
TYR A 375
TYR A 440
LEU A 414
 None
 1.37A 5bmvB-5gy0A:
undetectable		 5bmvB-5gy0A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hly INHIBIN BETA A CHAIN

(Homo sapiens) 		PF00019
(TGF_beta)
PF00688
(TGFb_propeptide) 		4 LYS A 134
ASP A 239
PRO A 291
LEU A 157
 None
 1.37A 5bmvB-5hlyA:
undetectable		 5bmvB-5hlyA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hmn AAC3-I

(uncultured
bacterium) 		PF00583
(Acetyltransf_1) 		4 ASP A  86
PRO A 130
TYR A 135
LEU A 134
 PG4  A 202 (-3.7A)
COA  A 201 (-3.9A)
COA  A 201 (-4.8A)
COA  A 201 (-3.9A)
 1.15A 5bmvB-5hmnA:
undetectable		 5bmvB-5hmnA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hsi PUTATIVE
DECARBOXYLASE

(Lactobacillus
brevis) 		PF00282
(Pyridoxal_deC) 		4 LYS A 606
ASP A 612
TYR A 508
LEU A 481
 None
 1.35A 5bmvB-5hsiA:
undetectable		 5bmvB-5hsiA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kbp GLYCOSYL HYDROLASE,
FAMILY 38

(Enterococcus
faecalis) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid) 		4 ASP A 125
TYR A  19
TYR A 569
LEU A 754
 None
 1.06A 5bmvB-5kbpA:
undetectable		 5bmvB-5kbpA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mq6 PYRIDINE
NUCLEOTIDE-DISULFIDE
OXIDOREDUCTASE-LIKE
PROTEIN

(Thermothelomyces
thermophila) 		PF07992
(Pyr_redox_2) 		4 LYS A 153
TYR A 137
TYR A 148
LEU A 143
 None
 1.31A 5bmvB-5mq6A:
undetectable		 5bmvB-5mq6A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oyp STRUCTURAL PROTEIN
VP2

(Sacbrood virus) 		no annotation 4 TYR B 110
PRO B  85
TYR B 222
LEU B 112
 None
 1.07A 5bmvB-5oypB:
undetectable		 5bmvB-5oypB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7

(Homo sapiens) 		PF00293
(NUDIX) 		4 TYR A  33
PRO A 113
TYR A  38
LEU A  36
 None
 1.32A 5bmvB-5t3pA:
undetectable		 5bmvB-5t3pA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tea INORGANIC
PYROPHOSPHATASE

(Neisseria
gonorrhoeae) 		PF00719
(Pyrophosphatase) 		4 ASP A  99
PRO A  54
TYR A  57
LEU A  74
 None
 1.26A 5bmvB-5teaA:
undetectable		 5bmvB-5teaA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tta PUTATIVE EXPORTED
PROTEIN

(Clostridioides
difficile) 		no annotation 4 ASP A 218
TYR A 156
PRO A 114
LEU A 106
 None
 1.10A 5bmvB-5ttaA:
undetectable		 5bmvB-5ttaA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v6h PDZ
DOMAIN-CONTAINING
PROTEIN GIPC2
UNCONVENTIONAL
MYOSIN-VI

(Mus musculus) 		no annotation 4 ASP A 251
TYR B1059
TYR B1089
LEU B1086
 None
 1.38A 5bmvB-5v6hA:
undetectable		 5bmvB-5v6hA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5whs CATALASE-PEROXIDASE

(Neurospora
crassa) 		no annotation 4 ASP A 395
TYR A 405
TYR A 346
LEU A 342
 None
 1.37A 5bmvB-5whsA:
undetectable		 5bmvB-5whsA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yh5 NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Staphylococcus
aureus) 		no annotation 4 ASP A 443
TYR A 458
PRO A 412
LEU A 462
 None
 1.32A 5bmvB-5yh5A:
undetectable		 5bmvB-5yh5A:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni) 		no annotation 4 ASP A 194
TYR A 277
PRO A 248
LEU A 251
 None
 1.16A 5bmvB-6b2wA:
undetectable		 5bmvB-6b2wA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bf6 INSULIN-DEGRADING
ENZYME

(Homo sapiens) 		no annotation 4 LYS A 571
TYR A 634
PRO A 532
LEU A 616
 None
 1.33A 5bmvB-6bf6A:
undetectable		 5bmvB-6bf6A:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c4r STAPHYLOPINE
DEHYDROGENASE

(Staphylococcus
aureus) 		no annotation 4 LYS A  75
ASP A  29
TYR A  44
LEU A  43
 None
 1.35A 5bmvB-6c4rA:
undetectable		 5bmvB-6c4rA:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dk2 -

(-) 		no annotation 4 ASP A  87
PRO A 144
TYR A 140
LEU A 136
 None
EDO  A 610 ( 4.9A)
None
None
 1.26A 5bmvB-6dk2A:
undetectable		 5bmvB-6dk2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6egx STRUCTURAL PROTEIN
VP2

(Sacbrood virus) 		no annotation 4 TYR B 110
PRO B  85
TYR B 222
LEU B 112
 None
 1.17A 5bmvB-6egxB:
undetectable		 5bmvB-6egxB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eh1 STRUCTURAL PROTEIN
VP2

(Sacbrood virus) 		no annotation 4 TYR B 110
PRO B  85
TYR B 222
LEU B 112
 None
 1.03A 5bmvB-6eh1B:
undetectable		 5bmvB-6eh1B:
undetectable