SIMILAR PATTERNS OF AMINO ACIDS FOR 5BMV_C_VLBC507

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b35 PROTEIN (CRICKET
PARALYSIS VIRUS,
VP1)
PROTEIN (CRICKET
PARALYSIS VIRUS,
VP3)

(Cricket
paralysis virus) 		PF08762
(CRPV_capsid)
no annotation 		4 ASP A 197
TYR C 257
PRO A 253
TYR A  96
 None
 1.14A 5bmvB-1b35A:
undetectable		 5bmvB-1b35A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhq CD11B

(Homo sapiens) 		PF00092
(VWA) 		4 LYS 1 187
ASP 1 134
PRO 1 193
LEU 1 198
 None
 1.30A 5bmvB-1bhq1:
undetectable		 5bmvB-1bhq1:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ed3 CLASS I MAJOR
HISTOCOMPATIBILITY
ANTIGEN RT1-AA

(Rattus
norvegicus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 ASP A  77
TYR A  99
TYR A 152
LEU A 156
 None
 1.35A 5bmvB-1ed3A:
undetectable		 5bmvB-1ed3A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h76 SEROTRANSFERRIN

(Sus scrofa) 		PF00405
(Transferrin) 		4 ASP A 461
TYR A 655
TYR A 663
LEU A 659
 None
 1.32A 5bmvB-1h76A:
undetectable		 5bmvB-1h76A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i60 IOLI PROTEIN

(Bacillus
subtilis) 		PF01261
(AP_endonuc_2) 		4 ASP A  49
PRO A  40
TYR A  42
LEU A  16
 None
 1.36A 5bmvB-1i60A:
undetectable		 5bmvB-1i60A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1js4 ENDO/EXOCELLULASE E4

(Thermobifida
fusca) 		PF00759
(Glyco_hydro_9)
PF00942
(CBM_3) 		4 ASP A 419
TYR A 363
TYR A 429
LEU A 402
 None
 1.35A 5bmvB-1js4A:
undetectable		 5bmvB-1js4A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k1x 4-ALPHA-GLUCANOTRANS
FERASE

(Thermococcus
litoralis) 		PF03065
(Glyco_hydro_57)
PF09094
(DUF1925)
PF09095
(DUF1926) 		4 LYS A 622
ASP A 481
PRO A 367
TYR A 365
 None
 1.24A 5bmvB-1k1xA:
undetectable		 5bmvB-1k1xA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lla HEMOCYANIN (SUBUNIT
TYPE II)

(Limulus
polyphemus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 ASP A 578
PRO A 110
TYR A 107
LEU A 520
 NA  A 631 (-3.6A)
None
None
None
 1.28A 5bmvB-1llaA:
undetectable		 5bmvB-1llaA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mpx ALPHA-AMINO ACID
ESTER HYDROLASE

(Xanthomonas
citri) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C) 		4 ASP A 501
TYR A 420
PRO A 629
LEU A 421
 None
 1.35A 5bmvB-1mpxA:
3.3		 5bmvB-1mpxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tqj RIBULOSE-PHOSPHATE
3-EPIMERASE

(Synechocystis
sp.) 		PF00834
(Ribul_P_3_epim) 		4 LYS A  76
TYR A  77
PRO A  51
LEU A  69
 None
 1.30A 5bmvB-1tqjA:
undetectable		 5bmvB-1tqjA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u0x NITROPHORIN 4

(Rhodnius
prolixus) 		PF02087
(Nitrophorin) 		4 LYS A 162
ASP A  27
PRO A  33
LEU A  31
 None
 1.24A 5bmvB-1u0xA:
undetectable		 5bmvB-1u0xA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2v ACTIN-RELATED
PROTEIN 3
ARP2/3 COMPLEX 34KDA
SUBUNIT

(Bos taurus) 		PF00022
(Actin)
PF04045
(P34-Arc) 		4 LYS A  99
ASP D  37
TYR A 100
LEU A  19
 None
 1.34A 5bmvB-1u2vA:
undetectable		 5bmvB-1u2vA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		4 LYS A1083
TYR A1080
TYR A1065
LEU A1077
 None
 1.21A 5bmvB-2b39A:
undetectable		 5bmvB-2b39A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c6y FORKHEAD BOX PROTEIN
K2

(Homo sapiens) 		PF00250
(Forkhead) 		4 ASP A  44
PRO A   4
TYR A   8
LEU A  11
 None
 1.24A 5bmvB-2c6yA:
undetectable		 5bmvB-2c6yA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eaa 7S GLOBULIN-3

(Vigna angularis) 		PF00190
(Cupin_1) 		4 ASP A 306
PRO A 335
TYR A 322
LEU A 301
 None
 1.35A 5bmvB-2eaaA:
undetectable		 5bmvB-2eaaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gnp TRANSCRIPTIONAL
REGULATOR

(Streptococcus
pneumoniae) 		PF04198
(Sugar-bind) 		4 LYS A 310
ASP A 315
TYR A  67
LEU A  64
 None
None
PEG  A 319 ( 3.8A)
PEG  A 319 ( 4.9A)
 1.21A 5bmvB-2gnpA:
undetectable		 5bmvB-2gnpA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nvv ACETYL-COA
HYDROLASE/TRANSFERAS
E FAMILY PROTEIN

(Porphyromonas
gingivalis) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		4 ASP A 172
TYR A 188
TYR A 282
LEU A 345
 ASP  A 172 ( 0.6A)
TYR  A 188 ( 1.3A)
TYR  A 282 ( 1.3A)
LEU  A 345 ( 0.6A)
 1.08A 5bmvB-2nvvA:
undetectable		 5bmvB-2nvvA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME

(Bos taurus) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 LYS A 471
TYR A 472
TYR A 525
LEU A 364
 CLU  A 808 (-3.7A)
CLU  A 808 (-3.4A)
None
None
 1.27A 5bmvB-2pncA:
undetectable		 5bmvB-2pncA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vl8 CYTOTOXIN L

(Paeniclostridium
sordellii) 		PF12918
(TcdB_N)
PF12919
(TcdA_TcdB) 		4 LYS A 119
ASP A 124
PRO A 291
LEU A 285
 None
 1.35A 5bmvB-2vl8A:
undetectable		 5bmvB-2vl8A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpw THIOSULFATE
REDUCTASE

(Thermus
thermophilus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 ASP A 673
TYR A 723
PRO A 447
LEU A 734
 None
None
None
MGD  A1765 (-4.9A)
 1.37A 5bmvB-2vpwA:
2.9		 5bmvB-2vpwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w55 XANTHINE
DEHYDROGENASE

(Rhodobacter
capsulatus) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 TYR B 319
PRO B 452
TYR B 624
LEU B 414
 None
 1.16A 5bmvB-2w55B:
undetectable		 5bmvB-2w55B:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x0i MALATE DEHYDROGENASE

(Archaeoglobus
fulgidus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 LYS A 115
ASP A 122
TYR A 331
LEU A 329
 None
 1.34A 5bmvB-2x0iA:
4.4		 5bmvB-2x0iA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xvg ALPHA XYLOSIDASE

(Cellvibrio
japonicus) 		PF01055
(Glyco_hydro_31)
PF16338
(DUF4968)
PF17137
(DUF5110) 		4 TYR A 261
PRO A 292
TYR A 299
LEU A 304
 None
 1.37A 5bmvB-2xvgA:
undetectable		 5bmvB-2xvgA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y89 PHOSPHORIBOSYL
ISOMERASE A

(Mycobacterium
tuberculosis) 		PF00977
(His_biosynth) 		4 ASP A  36
PRO A   8
TYR A 230
LEU A 229
 None
 1.25A 5bmvB-2y89A:
undetectable		 5bmvB-2y89A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE

(Mus musculus) 		PF05889
(SepSecS) 		4 ASP A 171
PRO A 430
TYR A 433
LEU A 364
 None
 1.15A 5bmvB-3bc8A:
undetectable		 5bmvB-3bc8A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdi UNCHARACTERIZED
PROTEIN TA0194

(Thermoplasma
acidophilum) 		PF00561
(Abhydrolase_1)
PF12146
(Hydrolase_4) 		4 ASP A 141
TYR A 168
PRO A 132
LEU A 151
 None
 1.38A 5bmvB-3bdiA:
3.7		 5bmvB-3bdiA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c1o EUGENOL SYNTHASE

(Clarkia breweri) 		PF05368
(NmrA) 		4 ASP A 173
PRO A 242
TYR A 177
LEU A 246
 None
 1.13A 5bmvB-3c1oA:
6.2		 5bmvB-3c1oA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwk PENICILLIN-BINDING
PROTEIN 2

(Staphylococcus
aureus) 		PF00905
(Transpeptidase)
PF00912
(Transgly) 		4 ASP A 241
PRO A 231
TYR A 226
LEU A 227
 None
 1.32A 5bmvB-3dwkA:
undetectable		 5bmvB-3dwkA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)

(Streptococcus
pneumoniae) 		PF14506
(CppA_N)
PF14507
(CppA_C) 		4 LYS A  99
TYR A 104
PRO A 134
LEU A  88
 None
 0.98A 5bmvB-3e0rA:
undetectable		 5bmvB-3e0rA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f6t ASPARTATE
AMINOTRANSFERASE

(Lactobacillus
acidophilus) 		PF00155
(Aminotran_1_2) 		4 LYS A 329
ASP A 165
TYR A 302
TYR A 297
 None
 1.06A 5bmvB-3f6tA:
undetectable		 5bmvB-3f6tA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fky GLUTAMINE SYNTHETASE

(Saccharomyces
cerevisiae) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 ASP A  32
TYR A 342
PRO A 341
LEU A 343
 None
 1.28A 5bmvB-3fkyA:
undetectable		 5bmvB-3fkyA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fxg RHAMNONATE
DEHYDRATASE

(Fusarium
graminearum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ASP A 164
TYR A 331
PRO A 367
LEU A 379
 None
 1.34A 5bmvB-3fxgA:
undetectable		 5bmvB-3fxgA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT

(Vibrio
vulnificus) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF13588
(HSDR_N_2) 		4 ASP A 367
TYR A 110
TYR A 181
LEU A 114
 None
 0.83A 5bmvB-3h1tA:
undetectable		 5bmvB-3h1tA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06

(Sarcoptes
scabiei) 		PF00089
(Trypsin) 		4 ASP A 226
TYR A 219
TYR A  86
LEU A 215
 None
 1.37A 5bmvB-3h7tA:
undetectable		 5bmvB-3h7tA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hig AMILORIDE-SENSITIVE
AMINE OXIDASE

(Homo sapiens) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 LYS A 462
ASP A 466
TYR A 463
LEU A 378
 TPQ  A 461 ( 3.4A)
None
TPQ  A 461 ( 4.5A)
None
 1.32A 5bmvB-3higA:
undetectable		 5bmvB-3higA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ie1 RIBONUCLEASE
TTHA0252

(Thermus
thermophilus) 		PF00753
(Lactamase_B)
PF07521
(RMMBL)
PF10996
(Beta-Casp) 		4 ASP A  63
PRO A   5
TYR A 159
LEU A 184
 ZN  A 452 (-2.5A)
None
None
None
 1.29A 5bmvB-3ie1A:
undetectable		 5bmvB-3ie1A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iv0 SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ASP A 105
TYR A  89
TYR A  68
LEU A  90
 None
 1.25A 5bmvB-3iv0A:
1.5		 5bmvB-3iv0A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j3i CAPSID PROTEIN

(Penicillium
chrysogenum
virus) 		no annotation 4 ASP A 557
PRO A 308
TYR A 312
LEU A 212
 None
 0.83A 5bmvB-3j3iA:
undetectable		 5bmvB-3j3iA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jux PROTEIN TRANSLOCASE
SUBUNIT SECA

(Thermotoga
maritima) 		PF00271
(Helicase_C)
PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		4 LYS A 346
ASP A 350
TYR A 374
LEU A 378
 None
 1.23A 5bmvB-3juxA:
2.3		 5bmvB-3juxA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3keb PROBABLE THIOL
PEROXIDASE

(Chromobacterium
violaceum) 		no annotation 4 ASP A  58
PRO A 136
TYR A 133
LEU A 130
 None
 1.09A 5bmvB-3kebA:
undetectable		 5bmvB-3kebA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kk7 PUTATIVE CELL
INVASION PROTEIN
WITH MAC/PERFORIN
DOMAIN

(Bacteroides
thetaiotaomicron) 		PF01823
(MACPF) 		4 ASP A 423
TYR A 393
TYR A 530
LEU A 466
 None
 1.28A 5bmvB-3kk7A:
undetectable		 5bmvB-3kk7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kny HYPOTHETICAL PROTEIN
BT_3535

(Bacteroides
thetaiotaomicron) 		no annotation 4 LYS A 158
TYR A 156
PRO A 188
LEU A 213
 None
 1.22A 5bmvB-3knyA:
undetectable		 5bmvB-3knyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l40 BRCT-CONTAINING
PROTEIN 1

(Schizosaccharomyces
pombe) 		PF16770
(RTT107_BRCT_5) 		4 ASP A 819
TYR A 809
TYR A 778
LEU A 806
 None
 1.31A 5bmvB-3l40A:
undetectable		 5bmvB-3l40A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lcm PUTATIVE
OXIDOREDUCTASE

(Streptococcus
mutans) 		PF02525
(Flavodoxin_2) 		4 ASP A  97
PRO A 152
TYR A 106
LEU A 113
 None
None
NAP  A 198 (-4.2A)
None
 0.92A 5bmvB-3lcmA:
2.1		 5bmvB-3lcmA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mtr NEURAL CELL ADHESION
MOLECULE 1

(Homo sapiens) 		PF00041
(fn3)
PF07679
(I-set) 		4 ASP A 469
PRO A 446
TYR A 477
LEU A 464
 None
 1.32A 5bmvB-3mtrA:
undetectable		 5bmvB-3mtrA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mtt PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT BETA

(Homo sapiens) 		PF16454
(PI3K_P85_iSH2) 		4 LYS A 558
PRO A 565
TYR A 460
LEU A 563
 None
 1.34A 5bmvB-3mttA:
undetectable		 5bmvB-3mttA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzb NICKEL-BINDING
PERIPLASMIC PROTEIN

(Escherichia
coli) 		PF00496
(SBP_bac_5) 		4 ASP A 432
TYR A 451
PRO A 404
LEU A 455
 None
 1.36A 5bmvB-3mzbA:
undetectable		 5bmvB-3mzbA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nnm CURA

(Lyngbya
majuscula) 		PF05721
(PhyH) 		4 ASP A  59
TYR A 193
TYR A 266
LEU A 169
 None
 1.38A 5bmvB-3nnmA:
undetectable		 5bmvB-3nnmA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opb SWI5-DEPENDENT HO
EXPRESSION PROTEIN 4

(Saccharomyces
cerevisiae) 		PF11701
(UNC45-central) 		4 LYS A 535
ASP A 588
TYR A 536
LEU A 499
 None
 1.29A 5bmvB-3opbA:
undetectable		 5bmvB-3opbA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pfe SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE

(Legionella
pneumophila) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 ASP A  98
TYR A 132
TYR A  26
LEU A  23
 None
 1.21A 5bmvB-3pfeA:
3.8		 5bmvB-3pfeA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qvi HISTO-ASPARTIC
PROTEASE

(Plasmodium
falciparum) 		PF00026
(Asp) 		4 ASP A  67
TYR A  99
TYR A  56
LEU A  20
 ASP  A  67 ( 0.6A)
TYR  A  99 ( 1.3A)
TYR  A  56 ( 1.3A)
LEU  A  20 ( 0.5A)
 1.20A 5bmvB-3qviA:
undetectable		 5bmvB-3qviA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqe MALONYL-COA-[ACYL-CA
RRIER-PROTEIN]
TRANSACYLASE

(Coxiella
burnetii) 		PF00698
(Acyl_transf_1) 		4 ASP A 216
PRO A  65
TYR A  97
LEU A  94
 None
None
None
GLY  A 314 ( 4.6A)
 1.08A 5bmvB-3tqeA:
undetectable		 5bmvB-3tqeA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u8p CYTOCHROME B562
INTEGRAL FUSION WITH
ENHANCED GREEN
FLUORESCENT PROTEIN

(Aequorea
victoria;
Escherichia
coli) 		PF01353
(GFP)
PF07361
(Cytochrom_B562) 		4 LYS A 146
ASP A  36
TYR A 147
PRO A  87
 None
None
None
HEM  A 347 ( 4.9A)
 1.04A 5bmvB-3u8pA:
undetectable		 5bmvB-3u8pA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vh0 UNCHARACTERIZED
PROTEIN YNCE

(Escherichia
coli) 		no annotation 4 ASP A  66
TYR A  44
TYR A  72
LEU A  57
 None
 1.31A 5bmvB-3vh0A:
undetectable		 5bmvB-3vh0A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a6e HYDROXYINDOLE
O-METHYLTRANSFERASE

(Homo sapiens) 		PF00891
(Methyltransf_2)
PF16864
(Dimerisation2) 		4 LYS A  74
ASP A  65
PRO A  43
LEU A  37
 SO4  A1353 (-3.2A)
None
None
None
 1.28A 5bmvB-4a6eA:
undetectable		 5bmvB-4a6eA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ag6 TYPE IV SECRETORY
PATHWAY VIRB4
COMPONENTS-LIKE
PROTEIN

(Thermoanaerobacter
pseudethanolicus) 		PF01935
(DUF87) 		4 ASP A 511
TYR A 447
PRO A 273
LEU A 435
 None
 1.15A 5bmvB-4ag6A:
undetectable		 5bmvB-4ag6A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ak1 BT_4661

(Bacteroides
thetaiotaomicron) 		PF16319
(DUF4958) 		4 ASP A 341
TYR A 399
PRO A 371
LEU A 378
 None
 1.37A 5bmvB-4ak1A:
undetectable		 5bmvB-4ak1A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b9y ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B

(Cellvibrio
japonicus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16338
(DUF4968)
PF17137
(DUF5110) 		4 ASP A 165
TYR A 201
TYR A 242
LEU A 245
 None
 1.32A 5bmvB-4b9yA:
undetectable		 5bmvB-4b9yA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cbw ACTIN, ALPHA
SKELETAL MUSCLE,
ACTIN

(Plasmodium
berghei;
synthetic
construct) 		PF00022
(Actin) 		4 LYS A 337
ASP A 155
TYR A 338
PRO A  28
 ATP  A1379 ( 3.8A)
CA  A1377 ( 4.3A)
None
None
 1.36A 5bmvB-4cbwA:
undetectable		 5bmvB-4cbwA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ecn LEUCINE-RICH REPEAT
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF14660
(DUF4458) 		4 LYS A 303
ASP A 298
PRO A 368
TYR A 504
 None
 1.36A 5bmvB-4ecnA:
undetectable		 5bmvB-4ecnA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eco UNCHARACTERIZED
PROTEIN

(Bacteroides
eggerthii) 		no annotation 4 LYS A 304
ASP A 299
PRO A 366
TYR A 502
 None
 1.24A 5bmvB-4ecoA:
undetectable		 5bmvB-4ecoA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4efh ACTIN-1

(Acanthamoeba
castellanii) 		PF00022
(Actin) 		4 LYS A 336
ASP A 154
TYR A 337
PRO A  27
 ADP  A 403 (-3.6A)
CA  A 401 ( 4.4A)
None
None
 1.38A 5bmvB-4efhA:
undetectable		 5bmvB-4efhA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f62 GERANYLTRANSTRANSFER
ASE

(Marinomonas sp.
MED121) 		PF00348
(polyprenyl_synt) 		4 LYS A 277
ASP A 283
TYR A 208
LEU A 205
 None
 1.37A 5bmvB-4f62A:
undetectable		 5bmvB-4f62A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gys ALLOPHANATE
HYDROLASE

(Granulibacter
bethesdensis) 		PF01425
(Amidase) 		4 ASP A 293
TYR A 393
PRO A 252
LEU A 365
 None
 0.91A 5bmvB-4gysA:
undetectable		 5bmvB-4gysA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hxe PUTATIVE
UNCHARACTERIZED
PROTEIN PH0594

(Pyrococcus
horikoshii) 		PF00326
(Peptidase_S9)
PF07676
(PD40) 		4 ASP B 329
TYR B 275
TYR B 314
LEU B 286
 None
 1.37A 5bmvB-4hxeB:
undetectable		 5bmvB-4hxeB:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4inz SOLUBLE EPOXIDE
HYDROLASE

(Bacillus
megaterium) 		PF00561
(Abhydrolase_1) 		4 ASP A  97
PRO A 172
TYR A 187
LEU A 179
 PEG  A 302 ( 4.7A)
None
None
None
 1.21A 5bmvB-4inzA:
2.8		 5bmvB-4inzA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jso OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		4 ASP A  33
PRO A 174
TYR A 187
LEU A 207
 CA  A 606 ( 3.4A)
None
None
None
 1.24A 5bmvB-4jsoA:
undetectable		 5bmvB-4jsoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pzl ADENYLATE KINASE

(Francisella
tularensis) 		PF00406
(ADK)
PF05191
(ADK_lid) 		4 ASP A 104
TYR A 182
PRO A  87
LEU A   6
 None
 0.97A 5bmvB-4pzlA:
3.6		 5bmvB-4pzlA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9z UNCHARACTERIZED
PROTEIN

(Mycobacterium
avium) 		PF13622
(4HBT_3) 		4 ASP A   7
PRO A 177
TYR A 194
LEU A 191
 None
 1.33A 5bmvB-4r9zA:
undetectable		 5bmvB-4r9zA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rz2 SITE-DETERMINING
PROTEIN

(Geobacillus
thermodenitrificans) 		PF10609
(ParA) 		4 LYS A  93
TYR A 101
TYR A 133
LEU A  55
 None
 1.38A 5bmvB-4rz2A:
5.1		 5bmvB-4rz2A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3t PENICILLIN-BINDING
PROTEIN 2

(Neisseria
gonorrhoeae) 		PF00905
(Transpeptidase) 		4 TYR A 422
PRO A 308
TYR A 383
LEU A 424
 None
 1.29A 5bmvB-4u3tA:
undetectable		 5bmvB-4u3tA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w5z CHITINASE 60

(Moritella
marina) 		PF00704
(Glyco_hydro_18) 		4 ASP A 151
TYR A 194
PRO A 193
LEU A 195
 ACT  A 404 (-2.7A)
None
None
None
 1.38A 5bmvB-4w5zA:
undetectable		 5bmvB-4w5zA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xb1 319AA LONG
HYPOTHETICAL
HOMOSERINE
DEHYDROGENASE

(Pyrococcus
horikoshii) 		PF00742
(Homoserine_dh)
PF03447
(NAD_binding_3) 		4 ASP A 307
TYR A 101
PRO A 118
TYR A 123
 None
None
None
MPD  A1004 ( 4.8A)
 1.33A 5bmvB-4xb1A:
undetectable		 5bmvB-4xb1A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yfj AMINOGLYCOSIDE
3'-N-ACETYLTRANSFERA
SE

(Pseudomonas
aeruginosa) 		PF00583
(Acetyltransf_1) 		4 ASP A 109
PRO A 151
TYR A 156
LEU A 155
 None
SO4  A 204 ( 4.6A)
None
SO4  A 201 ( 4.4A)
 1.05A 5bmvB-4yfjA:
undetectable		 5bmvB-4yfjA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z8n RETICULOCYTE-BINDING
PROTEIN 2A

(Plasmodium
vivax) 		no annotation 4 LYS A 192
TYR A 205
TYR A 410
LEU A 294
 None
 1.35A 5bmvB-4z8nA:
undetectable		 5bmvB-4z8nA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zdl O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE

(Homo sapiens) 		PF05889
(SepSecS) 		4 ASP A 171
PRO A 430
TYR A 433
LEU A 364
 None
 1.08A 5bmvB-4zdlA:
undetectable		 5bmvB-4zdlA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zkt BOTULINUM NEUROTOXIN
TYPE E,
NONTOXIC-NONHEMAGGLU
TININ COMPONENT,
NTNH

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07953
(Toxin_R_bind_N)
PF08470
(NTNH_C) 		4 ASP B 711
TYR B 318
TYR B 178
LEU B 322
 None
 1.11A 5bmvB-4zktB:
undetectable		 5bmvB-4zktB:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dld UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Burkholderia
vietnamiensis) 		PF02350
(Epimerase_2) 		4 ASP A 290
PRO A 255
TYR A 244
LEU A 260
 EDO  A 503 (-3.2A)
None
None
None
 1.30A 5bmvB-5dldA:
7.3		 5bmvB-5dldA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dqs ELONGATION FACTOR
1-GAMMA

(Homo sapiens) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 ASP A 143
PRO A 178
TYR A 172
LEU A 209
 None
 1.10A 5bmvB-5dqsA:
undetectable		 5bmvB-5dqsA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5epg ALDEHYDE OXIDASE

(Homo sapiens) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		4 TYR A 898
PRO A1011
TYR A1164
LEU A 973
 None
 1.29A 5bmvB-5epgA:
undetectable		 5bmvB-5epgA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gk2 KETOSYNTHASE STLD

(Photorhabdus
laumondii) 		PF08541
(ACP_syn_III_C) 		4 LYS A  49
TYR A  50
PRO A  18
TYR A  53
 None
 1.37A 5bmvB-5gk2A:
undetectable		 5bmvB-5gk2A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gy0 GLUCANASE

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9)
PF00942
(CBM_3) 		4 ASP A 430
TYR A 375
TYR A 440
LEU A 414
 None
 1.37A 5bmvB-5gy0A:
undetectable		 5bmvB-5gy0A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hly INHIBIN BETA A CHAIN

(Homo sapiens) 		PF00019
(TGF_beta)
PF00688
(TGFb_propeptide) 		4 LYS A 134
ASP A 239
PRO A 291
LEU A 157
 None
 1.37A 5bmvB-5hlyA:
undetectable		 5bmvB-5hlyA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hmn AAC3-I

(uncultured
bacterium) 		PF00583
(Acetyltransf_1) 		4 ASP A  86
PRO A 130
TYR A 135
LEU A 134
 PG4  A 202 (-3.7A)
COA  A 201 (-3.9A)
COA  A 201 (-4.8A)
COA  A 201 (-3.9A)
 1.15A 5bmvB-5hmnA:
undetectable		 5bmvB-5hmnA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hsi PUTATIVE
DECARBOXYLASE

(Lactobacillus
brevis) 		PF00282
(Pyridoxal_deC) 		4 LYS A 606
ASP A 612
TYR A 508
LEU A 481
 None
 1.35A 5bmvB-5hsiA:
undetectable		 5bmvB-5hsiA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kbp GLYCOSYL HYDROLASE,
FAMILY 38

(Enterococcus
faecalis) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid) 		4 ASP A 125
TYR A  19
TYR A 569
LEU A 754
 None
 1.06A 5bmvB-5kbpA:
undetectable		 5bmvB-5kbpA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mq6 PYRIDINE
NUCLEOTIDE-DISULFIDE
OXIDOREDUCTASE-LIKE
PROTEIN

(Thermothelomyces
thermophila) 		PF07992
(Pyr_redox_2) 		4 LYS A 153
TYR A 137
TYR A 148
LEU A 143
 None
 1.31A 5bmvB-5mq6A:
undetectable		 5bmvB-5mq6A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oyp STRUCTURAL PROTEIN
VP2

(Sacbrood virus) 		no annotation 4 TYR B 110
PRO B  85
TYR B 222
LEU B 112
 None
 1.07A 5bmvB-5oypB:
undetectable		 5bmvB-5oypB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7

(Homo sapiens) 		PF00293
(NUDIX) 		4 TYR A  33
PRO A 113
TYR A  38
LEU A  36
 None
 1.32A 5bmvB-5t3pA:
undetectable		 5bmvB-5t3pA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tea INORGANIC
PYROPHOSPHATASE

(Neisseria
gonorrhoeae) 		PF00719
(Pyrophosphatase) 		4 ASP A  99
PRO A  54
TYR A  57
LEU A  74
 None
 1.26A 5bmvB-5teaA:
undetectable		 5bmvB-5teaA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tta PUTATIVE EXPORTED
PROTEIN

(Clostridioides
difficile) 		no annotation 4 ASP A 218
TYR A 156
PRO A 114
LEU A 106
 None
 1.10A 5bmvB-5ttaA:
undetectable		 5bmvB-5ttaA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v6h PDZ
DOMAIN-CONTAINING
PROTEIN GIPC2
UNCONVENTIONAL
MYOSIN-VI

(Mus musculus) 		no annotation 4 ASP A 251
TYR B1059
TYR B1089
LEU B1086
 None
 1.38A 5bmvB-5v6hA:
undetectable		 5bmvB-5v6hA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5whs CATALASE-PEROXIDASE

(Neurospora
crassa) 		no annotation 4 ASP A 395
TYR A 405
TYR A 346
LEU A 342
 None
 1.37A 5bmvB-5whsA:
undetectable		 5bmvB-5whsA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yh5 NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Staphylococcus
aureus) 		no annotation 4 ASP A 443
TYR A 458
PRO A 412
LEU A 462
 None
 1.32A 5bmvB-5yh5A:
undetectable		 5bmvB-5yh5A:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni) 		no annotation 4 ASP A 194
TYR A 277
PRO A 248
LEU A 251
 None
 1.16A 5bmvB-6b2wA:
undetectable		 5bmvB-6b2wA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bf6 INSULIN-DEGRADING
ENZYME

(Homo sapiens) 		no annotation 4 LYS A 571
TYR A 634
PRO A 532
LEU A 616
 None
 1.33A 5bmvB-6bf6A:
undetectable		 5bmvB-6bf6A:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c4r STAPHYLOPINE
DEHYDROGENASE

(Staphylococcus
aureus) 		no annotation 4 LYS A  75
ASP A  29
TYR A  44
LEU A  43
 None
 1.35A 5bmvB-6c4rA:
undetectable		 5bmvB-6c4rA:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dk2 -

(-) 		no annotation 4 ASP A  87
PRO A 144
TYR A 140
LEU A 136
 None
EDO  A 610 ( 4.9A)
None
None
 1.26A 5bmvB-6dk2A:
undetectable		 5bmvB-6dk2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6egx STRUCTURAL PROTEIN
VP2

(Sacbrood virus) 		no annotation 4 TYR B 110
PRO B  85
TYR B 222
LEU B 112
 None
 1.17A 5bmvB-6egxB:
undetectable		 5bmvB-6egxB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eh1 STRUCTURAL PROTEIN
VP2

(Sacbrood virus) 		no annotation 4 TYR B 110
PRO B  85
TYR B 222
LEU B 112
 None
 1.03A 5bmvB-6eh1B:
undetectable		 5bmvB-6eh1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bja TRANSCRIPTION
REGULATORY PROTEIN
MOTA

(Escherichia
virus T4) 		PF09114
(MotA_activ) 		4 VAL A  49
ASN A  50
ILE A  53
VAL A  37
 None
 0.72A 5bmvC-1bjaA:
undetectable		 5bmvC-1bjaA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bu8 PROTEIN (PANCREATIC
LIPASE RELATED
PROTEIN 2)

(Rattus
norvegicus) 		PF00151
(Lipase)
PF01477
(PLAT) 		4 VAL A 124
ILE A 128
PHE A  72
VAL A  74
 None
 0.67A 5bmvC-1bu8A:
undetectable		 5bmvC-1bu8A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bu8 PROTEIN (PANCREATIC
LIPASE RELATED
PROTEIN 2)

(Rattus
norvegicus) 		PF00151
(Lipase)
PF01477
(PLAT) 		4 VAL A 124
ILE A 128
PHE A  72
VAL A 104
 None
 0.77A 5bmvC-1bu8A:
undetectable		 5bmvC-1bu8A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dcu FRUCTOSE-1,6-BISPHOS
PHATASE

(Pisum sativum) 		PF00316
(FBPase) 		4 VAL A  41
ILE A  45
PHE A 125
VAL A 123
 None
 0.78A 5bmvC-1dcuA:
undetectable		 5bmvC-1dcuA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dg4 DNAK

(Escherichia
coli) 		PF00012
(HSP70) 		4 VAL A 474
ILE A 472
VAL A 436
ILE A 438
 None
 0.80A 5bmvC-1dg4A:
undetectable		 5bmvC-1dg4A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dl5 PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Thermotoga
maritima) 		PF01135
(PCMT) 		5 VAL A 154
ASN A 176
ILE A 175
PHE A 186
ILE A  82
 None
 1.33A 5bmvC-1dl5A:
undetectable		 5bmvC-1dl5A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dl5 PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Thermotoga
maritima) 		PF01135
(PCMT) 		5 VAL A 154
ASN A 176
PHE A 186
VAL A 173
ILE A  82
 None
 1.40A 5bmvC-1dl5A:
undetectable		 5bmvC-1dl5A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1goj KINESIN HEAVY CHAIN

(Neurospora
crassa) 		PF00225
(Kinesin) 		4 VAL A 111
ILE A 115
VAL A  84
ILE A 304
 None
 0.75A 5bmvC-1gojA:
undetectable		 5bmvC-1gojA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gqr ACETYLCHOLINESTERASE

(Tetronarce
californica) 		PF00135
(COesterase) 		5 VAL A 113
ILE A 196
PHE A 219
VAL A 194
ILE A 184
 None
 1.39A 5bmvC-1gqrA:
undetectable		 5bmvC-1gqrA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gxh COLICIN E8 IMMUNITY
PROTEIN

(Escherichia
coli) 		PF01320
(Colicin_Pyocin) 		4 PRO A  63
VAL A  66
ILE A  70
ILE A  23
 None
 0.79A 5bmvC-1gxhA:
undetectable		 5bmvC-1gxhA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h32 CYTOCHROME C

(Rhodovulum
sulfidophilum) 		PF00034
(Cytochrom_C) 		4 PRO B   5
VAL B   8
ILE B  10
VAL B  81
 None
 0.68A 5bmvC-1h32B:
undetectable		 5bmvC-1h32B:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hcy ARTHROPODAN
HEMOCYANIN

(Panulirus
interruptus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 VAL A 416
ILE A 464
PHE A 478
VAL A 584
 None
 0.60A 5bmvC-1hcyA:
undetectable		 5bmvC-1hcyA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E SMALL SUBUNIT

(Galdieria
partita) 		PF00101
(RuBisCO_small) 		4 PRO B  80
VAL B  83
ILE B  87
ILE B  34
 None
 0.78A 5bmvC-1iwaB:
undetectable		 5bmvC-1iwaB:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j32 ASPARTATE
AMINOTRANSFERASE

(Phormidium
lapideum) 		PF00155
(Aminotran_1_2) 		5 PRO A 128
VAL A 131
ILE A 111
VAL A 117
ILE A 119
 None
 1.47A 5bmvC-1j32A:
2.5		 5bmvC-1j32A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jn5 TAP

(Homo sapiens) 		PF02136
(NTF2) 		4 VAL B 387
PHE B 479
VAL B 481
ILE B 483
 None
 0.59A 5bmvC-1jn5B:
undetectable		 5bmvC-1jn5B:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k5c ENDOPOLYGALACTURONAS
E

(Chondrostereum
purpureum) 		PF00295
(Glyco_hydro_28) 		4 VAL A 162
ILE A 164
PHE A 155
VAL A 124
 None
 0.73A 5bmvC-1k5cA:
undetectable		 5bmvC-1k5cA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k5c ENDOPOLYGALACTURONAS
E

(Chondrostereum
purpureum) 		PF00295
(Glyco_hydro_28) 		4 VAL A 162
ILE A 164
PHE A 155
VAL A 157
 None
 0.66A 5bmvC-1k5cA:
undetectable		 5bmvC-1k5cA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m0w GLUTATHIONE
SYNTHETASE

(Saccharomyces
cerevisiae) 		PF03199
(GSH_synthase)
PF03917
(GSH_synth_ATP) 		4 VAL A  18
ASN A  19
VAL A  46
ILE A  48
 None
 0.65A 5bmvC-1m0wA:
undetectable		 5bmvC-1m0wA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n26 IL-6 RECEPTOR ALPHA
CHAIN

(Homo sapiens) 		PF00047
(ig)
PF09240
(IL6Ra-bind) 		4 VAL A 217
ILE A 260
VAL A 271
ILE A 203
 None
 0.80A 5bmvC-1n26A:
undetectable		 5bmvC-1n26A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qfh PROTEIN (GELATION
FACTOR)

(Dictyostelium
discoideum) 		PF00630
(Filamin) 		5 VAL A 717
ILE A 674
PHE A 691
VAL A 693
ILE A 695
 None
 1.37A 5bmvC-1qfhA:
undetectable		 5bmvC-1qfhA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rgy BETA-LACTAMASE

(Citrobacter
freundii) 		PF00144
(Beta-lactamase) 		4 VAL A  12
ASN A  13
ILE A  16
VAL A  30
 None
 0.78A 5bmvC-1rgyA:
undetectable		 5bmvC-1rgyA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sky F1-ATPASE

(Bacillus sp.
PS3) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		5 PRO B 331
VAL B 334
ASN B 333
ILE B 337
ILE B 168
 None
 1.45A 5bmvC-1skyB:
3.0		 5bmvC-1skyB:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1spi FRUCTOSE
1,6-BISPHOSPHATASE

(Spinacia
oleracea) 		PF00316
(FBPase) 		4 VAL A  43
ILE A  47
PHE A 127
VAL A 125
 None
 0.73A 5bmvC-1spiA:
undetectable		 5bmvC-1spiA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1thg LIPASE 2

(Galactomyces
candidus) 		PF00135
(COesterase) 		5 VAL A 126
ILE A 213
PHE A 242
VAL A 211
ILE A 201
 None
 1.43A 5bmvC-1thgA:
2.4		 5bmvC-1thgA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2h AORTIC
PREFERENTIALLY
EXPRESSED PROTEIN 1

(Homo sapiens) 		PF07679
(I-set) 		4 PRO A  20
VAL A  43
ILE A  41
VAL A  51
 None
 0.67A 5bmvC-1u2hA:
undetectable		 5bmvC-1u2hA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ulv GLUCODEXTRANASE

(Arthrobacter
globiformis) 		PF00723
(Glyco_hydro_15)
PF09136
(Glucodextran_B)
PF09137
(Glucodextran_N)
PF09985
(Glucodextran_C) 		4 VAL A 928
ILE A 846
PHE A 822
VAL A 811
 None
 0.59A 5bmvC-1ulvA:
undetectable		 5bmvC-1ulvA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5b 3-ISOPROPYLMALATE
DEHYDROGENASE

(Bacillus
coagulans) 		PF00180
(Iso_dh) 		4 PRO A  15
ILE A  22
PHE A  38
VAL A   7
 None
 0.78A 5bmvC-1v5bA:
undetectable		 5bmvC-1v5bA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vhe AMINOPEPTIDASE/GLUCA
NASE HOMOLOG

(Bacillus
subtilis) 		PF05343
(Peptidase_M42) 		4 ILE A 343
PHE A 234
VAL A 236
ILE A 185
 None
 0.72A 5bmvC-1vheA:
3.7		 5bmvC-1vheA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE

(Saccharomyces
cerevisiae) 		PF00171
(Aldedh) 		4 VAL A 162
ASN A 163
ILE A 166
ILE A 129
 None
 0.54A 5bmvC-1vluA:
undetectable		 5bmvC-1vluA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vma CELL DIVISION
PROTEIN FTSY

(Thermotoga
maritima) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 VAL A  94
ILE A 180
VAL A 203
ILE A 207
 None
 0.76A 5bmvC-1vmaA:
4.1		 5bmvC-1vmaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vqt OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Thermotoga
maritima) 		PF00215
(OMPdecase) 		4 VAL A  62
ILE A  66
PHE A  77
VAL A  79
 None
 0.79A 5bmvC-1vqtA:
undetectable		 5bmvC-1vqtA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vsq MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT

(Escherichia
coli) 		PF03830
(PTSIIB_sorb) 		4 PRO C 247
VAL C 250
VAL C 263
ILE C 169
 None
 0.67A 5bmvC-1vsqC:
3.1		 5bmvC-1vsqC:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wlh GELATION FACTOR

(Dictyostelium
discoideum) 		PF00630
(Filamin) 		5 VAL A 615
ILE A 574
PHE A 591
VAL A 593
ILE A 595
 None
 1.45A 5bmvC-1wlhA:
undetectable		 5bmvC-1wlhA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wy1 HYPOTHETICAL PROTEIN
PH0671

(Pyrococcus
horikoshii) 		PF01923
(Cob_adeno_trans) 		4 ASN A  31
ILE A  27
PHE A 136
ILE A  76
 None
 0.70A 5bmvC-1wy1A:
undetectable		 5bmvC-1wy1A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xrc S-ADENOSYLMETHIONINE
SYNTHETASE

(Escherichia
coli) 		PF00438
(S-AdoMet_synt_N)
PF02772
(S-AdoMet_synt_M)
PF02773
(S-AdoMet_synt_C) 		4 VAL A  52
ILE A  95
VAL A  26
ILE A  22
 None
 0.80A 5bmvC-1xrcA:
undetectable		 5bmvC-1xrcA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yxm PEROXISOMAL TRANS
2-ENOYL COA
REDUCTASE

(Homo sapiens) 		PF13561
(adh_short_C2) 		4 VAL A 243
PHE A 103
VAL A 105
ILE A 157
 None
 0.80A 5bmvC-1yxmA:
7.2		 5bmvC-1yxmA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zcl PROTEIN TYROSINE
PHOSPHATASE 4A1

(Rattus
norvegicus) 		PF00782
(DSPc) 		4 PRO A 112
VAL A 115
VAL A  12
ILE A  21
 None
 0.64A 5bmvC-1zclA:
undetectable		 5bmvC-1zclA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zpv ACT DOMAIN PROTEIN

(Streptococcus
pneumoniae) 		PF13740
(ACT_6) 		4 VAL A   7
ILE A   5
VAL A  19
ILE A  15
 None
 0.80A 5bmvC-1zpvA:
undetectable		 5bmvC-1zpvA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zpv ACT DOMAIN PROTEIN

(Streptococcus
pneumoniae) 		PF13740
(ACT_6) 		4 VAL A  19
ILE A  15
VAL A   7
ILE A   5
 None
 0.69A 5bmvC-1zpvA:
undetectable		 5bmvC-1zpvA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zun SULFATE
ADENYLYLTRANSFERASE
SUBUNIT 2

(Pseudomonas
syringae) 		PF01507
(PAPS_reduct) 		5 PRO A 184
VAL A 182
ILE A 180
VAL A  22
ILE A  19
 None
 1.38A 5bmvC-1zunA:
undetectable		 5bmvC-1zunA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ak3 ADENYLATE KINASE
ISOENZYME-3

(Bos taurus) 		PF00406
(ADK)
PF05191
(ADK_lid) 		4 VAL A  21
ILE A  25
VAL A 206
ILE A 202
 None
 0.78A 5bmvC-2ak3A:
4.3		 5bmvC-2ak3A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ash QUEUINE
TRNA-RIBOSYLTRANSFER
ASE

(Thermotoga
maritima) 		PF01702
(TGT) 		4 VAL A 342
ILE A 346
VAL A 253
ILE A 249
 None
 0.78A 5bmvC-2ashA:
undetectable		 5bmvC-2ashA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b67 COG0778:
NITROREDUCTASE

(Streptococcus
pneumoniae) 		PF00881
(Nitroreductase) 		5 PRO A  23
VAL A  26
ILE A  30
PHE A  47
VAL A  49
 None
 0.59A 5bmvC-2b67A:
undetectable		 5bmvC-2b67A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bku IMPORTIN BETA-1
SUBUNIT

(Saccharomyces
cerevisiae) 		PF03810
(IBN_N)
PF13513
(HEAT_EZ) 		4 PRO B 497
VAL B 500
ILE B 504
PHE B 545
 None
 0.72A 5bmvC-2bkuB:
undetectable		 5bmvC-2bkuB:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bmf RNA HELICASE

(Dengue virus) 		PF07652
(Flavi_DEAD) 		5 PRO A 239
VAL A 257
ILE A 220
VAL A 208
ILE A 212
 None
 1.31A 5bmvC-2bmfA:
undetectable		 5bmvC-2bmfA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bv5 TYROSINE-PROTEIN
PHOSPHATASE,
NON-RECEPTOR TYPE 5

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 VAL A 454
PHE A 432
VAL A 372
ILE A 468
 None
 0.74A 5bmvC-2bv5A:
undetectable		 5bmvC-2bv5A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1i PEPTIDOGLYCAN GLCNAC
DEACETYLASE

(Streptococcus
pneumoniae) 		PF01522
(Polysacc_deac_1) 		4 VAL A 313
ILE A 316
PHE A 299
VAL A 301
 None
 0.71A 5bmvC-2c1iA:
undetectable		 5bmvC-2c1iA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2drh 361AA LONG
HYPOTHETICAL
D-AMINOPEPTIDASE

(Pyrococcus
horikoshii) 		PF03576
(Peptidase_S58) 		5 PRO A  80
ILE A  96
PHE A 284
VAL A 282
ILE A 280
 None
 1.09A 5bmvC-2drhA:
undetectable		 5bmvC-2drhA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f2a GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Staphylococcus
aureus) 		PF01425
(Amidase) 		4 PRO A  22
VAL A  25
ILE A  29
ILE A  15
 None
 0.74A 5bmvC-2f2aA:
undetectable		 5bmvC-2f2aA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fhx SPM-1

(Pseudomonas
aeruginosa) 		PF00753
(Lactamase_B) 		4 PRO B 297
VAL B 300
ASN B 301
ILE B 304
 None
 0.71A 5bmvC-2fhxB:
undetectable		 5bmvC-2fhxB:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fnu AMINOTRANSFERASE

(Helicobacter
pylori) 		PF01041
(DegT_DnrJ_EryC1) 		4 PRO A 348
ILE A 288
VAL A 365
ILE A 361
 None
 0.79A 5bmvC-2fnuA:
undetectable		 5bmvC-2fnuA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gwo DUAL SPECIFICITY
PROTEIN PHOSPHATASE
13

(Homo sapiens) 		PF00782
(DSPc) 		4 VAL A 119
ILE A 123
VAL A  76
ILE A 102
 None
 0.72A 5bmvC-2gwoA:
undetectable		 5bmvC-2gwoA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h7w CHAGASIN

(Trypanosoma
cruzi) 		PF09394
(Inhibitor_I42) 		4 VAL A  75
ILE A  24
PHE A 103
VAL A  85
 None
 0.78A 5bmvC-2h7wA:
undetectable		 5bmvC-2h7wA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hig 6-PHOSPHO-1-FRUCTOKI
NASE

(Trypanosoma
brucei) 		PF00365
(PFK) 		4 VAL A 115
ILE A 119
PHE A 194
VAL A 196
 None
 0.77A 5bmvC-2higA:
undetectable		 5bmvC-2higA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iex DIHYDROXYNAPTHOIC
ACID SYNTHETASE

(Geobacillus
kaustophilus) 		PF00378
(ECH_1) 		4 PRO A  38
VAL A  41
ASN A  42
ILE A  45
 None
 0.43A 5bmvC-2iexA:
undetectable		 5bmvC-2iexA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iq7 ENDOPOLYGALACTURONAS
E

(Colletotrichum
lupini) 		PF00295
(Glyco_hydro_28) 		4 VAL A 188
ILE A 190
PHE A 180
VAL A 182
 None
 0.79A 5bmvC-2iq7A:
undetectable		 5bmvC-2iq7A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3e T7I23.11 PROTEIN

(Arabidopsis
thaliana) 		PF04548
(AIG1) 		4 VAL A  53
ASN A  54
ILE A  57
VAL A  77
 None
 0.77A 5bmvC-2j3eA:
4.1		 5bmvC-2j3eA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mbg RALA-BINDING PROTEIN
1

(Homo sapiens) 		PF00620
(RhoGAP) 		5 PRO A 260
VAL A 220
ILE A 217
PHE A 213
ILE A 230
 None
 1.48A 5bmvC-2mbgA:
undetectable		 5bmvC-2mbgA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4z METAL-DEPENDENT
HYDROLASES OF THE
BETA-LACTAMASE
SUPERFAMILY II

(Caldanaerobacter
subterraneus) 		PF00753
(Lactamase_B) 		4 VAL A  47
ILE A  45
PHE A 146
VAL A 184
 None
 0.66A 5bmvC-2p4zA:
undetectable		 5bmvC-2p4zA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2paa PHOSPHOGLYCERATE
KINASE, TESTIS
SPECIFIC

(Mus musculus) 		PF00162
(PGK) 		5 PRO A 282
ASN A 323
ILE A 326
PHE A 232
VAL A 280
 None
 1.37A 5bmvC-2paaA:
undetectable		 5bmvC-2paaA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ph7 UNCHARACTERIZED
PROTEIN AF_2093

(Archaeoglobus
fulgidus) 		no annotation 5 PRO A 203
VAL A 201
PHE A 118
VAL A 114
ILE A 110
 None
 1.42A 5bmvC-2ph7A:
undetectable		 5bmvC-2ph7A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pok PEPTIDASE,
M20/M25/M40 FAMILY

(Streptococcus
pneumoniae) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 PRO A 341
VAL A 344
ILE A 348
VAL A 333
 None
 0.44A 5bmvC-2pokA:
undetectable		 5bmvC-2pokA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q4x SEED MATURATION
PROTEIN PM36 HOMOLOG

(Arabidopsis
thaliana) 		PF03070
(TENA_THI-4) 		5 PRO A 158
VAL A 159
PHE A  40
VAL A  28
ILE A  30
 None
 1.18A 5bmvC-2q4xA:
undetectable		 5bmvC-2q4xA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qlv CARBON CATABOLITE
DEREPRESSING PROTEIN
KINASE

(Saccharomyces
cerevisiae) 		PF16579
(AdenylateSensor) 		4 PRO A 515
VAL A 518
ILE A 522
VAL A 582
 None
 0.66A 5bmvC-2qlvA:
undetectable		 5bmvC-2qlvA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r6r CELL DIVISION
PROTEIN FTSZ

(Aquifex
aeolicus) 		PF00091
(Tubulin)
PF12327
(FtsZ_C) 		4 VAL 1 275
ILE 1 279
VAL 1 305
ILE 1 303
 None
 0.65A 5bmvC-2r6r1:
26.8		 5bmvC-2r6r1:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r6r CELL DIVISION
PROTEIN FTSZ

(Aquifex
aeolicus) 		PF00091
(Tubulin)
PF12327
(FtsZ_C) 		4 VAL 1 305
ILE 1 303
VAL 1 275
ILE 1 279
 None
 0.72A 5bmvC-2r6r1:
26.8		 5bmvC-2r6r1:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9v ATP SYNTHASE SUBUNIT
ALPHA

(Thermotoga
maritima) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		5 PRO A 332
VAL A 335
ASN A 334
ILE A 338
ILE A 169
 None
 1.47A 5bmvC-2r9vA:
undetectable		 5bmvC-2r9vA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rhq PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Staphylococcus
haemolyticus) 		PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		4 VAL B 420
ASN B 421
ILE B 424
VAL B 472
 None
 0.69A 5bmvC-2rhqB:
undetectable		 5bmvC-2rhqB:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vga PROTEIN A41

(Vaccinia virus) 		PF02250
(Orthopox_35kD) 		4 VAL A  18
ILE A  16
VAL A 106
ILE A 108
 None
 0.76A 5bmvC-2vgaA:
undetectable		 5bmvC-2vgaA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vtx NPM-A PROTEIN

(Xenopus laevis) 		PF03066
(Nucleoplasmin) 		4 VAL A  50
ILE A 113
PHE A 102
VAL A  63
 None
 0.71A 5bmvC-2vtxA:
undetectable		 5bmvC-2vtxA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w0m SSO2452

(Sulfolobus
solfataricus) 		PF06745
(ATPase) 		4 VAL A 110
ASN A 111
ILE A 114
VAL A 153
 None
 0.75A 5bmvC-2w0mA:
undetectable		 5bmvC-2w0mA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3j CARBOHYDRATE BINDING
MODULE

(uncultured
bacterium) 		PF16990
(CBM_35) 		4 VAL A  71
ILE A  78
VAL A  97
ILE A  57
 None
 0.64A 5bmvC-2w3jA:
undetectable		 5bmvC-2w3jA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3n CARBONIC ANHYDRASE 2

(Cryptococcus
neoformans) 		PF00484
(Pro_CA) 		4 VAL A 184
ILE A 190
VAL A 119
ILE A  66
 None
 0.74A 5bmvC-2w3nA:
undetectable		 5bmvC-2w3nA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wok CLAVULANIC ACID
BIOSYNTHESIS
OLIGOPEPTIDE BINDING
PROTEIN 2

(Streptomyces
clavuligerus) 		PF00496
(SBP_bac_5) 		4 VAL A 490
ASN A 491
ILE A 494
VAL A 468
 None
 0.78A 5bmvC-2wokA:
undetectable		 5bmvC-2wokA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xdq LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Thermosynechococcus
elongatus) 		PF00148
(Oxidored_nitro) 		5 PRO B 213
ASN B 167
ILE B 200
VAL B 143
ILE B 147
 None
 1.47A 5bmvC-2xdqB:
2.3		 5bmvC-2xdqB:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y5w KINESIN HEAVY CHAIN

(Drosophila
melanogaster) 		PF00225
(Kinesin) 		5 PRO A 116
VAL A 119
ASN A 120
VAL A 186
ILE A 190
 None
 1.35A 5bmvC-2y5wA:
undetectable		 5bmvC-2y5wA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE

(Bifidobacterium
longum) 		PF12905
(Glyco_hydro_101)
PF17451
(Glyco_hyd_101C) 		4 VAL A1233
PHE A1247
VAL A1250
ILE A1252
 None
 0.77A 5bmvC-2zxqA:
undetectable		 5bmvC-2zxqA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al0 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Thermotoga
maritima) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		5 PRO B 468
ASN B 472
ILE B 475
PHE B 454
VAL B 458
 C  E  56 ( 3.8A)
C  E  56 ( 4.0A)
None
None
None
 1.25A 5bmvC-3al0B:
undetectable		 5bmvC-3al0B:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3any ETHANOLAMINE
AMMONIA-LYASE HEAVY
CHAIN

(Escherichia
coli) 		PF06751
(EutB) 		5 VAL A 323
ASN A 324
ILE A 322
PHE A 321
ILE A 248
 None
2A3  A 602 ( 4.9A)
None
None
None
 1.41A 5bmvC-3anyA:
undetectable		 5bmvC-3anyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cvw RE11660P

(Drosophila
melanogaster) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		4 PRO A  89
VAL A  92
ILE A  96
VAL A  85
 None
 0.78A 5bmvC-3cvwA:
undetectable		 5bmvC-3cvwA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3czc RMPB

(Streptococcus
mutans) 		PF02302
(PTS_IIB) 		4 VAL A  55
ILE A  53
VAL A  22
ILE A  18
 None
 0.80A 5bmvC-3czcA:
undetectable		 5bmvC-3czcA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dob HEAT SHOCK 70 KDA
PROTEIN F44E5.5

(Caenorhabditis
elegans) 		PF00012
(HSP70) 		4 VAL A 443
ILE A 404
VAL A 489
ILE A 504
 None
 0.71A 5bmvC-3dobA:
undetectable		 5bmvC-3dobA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e48 PUTATIVE
NUCLEOSIDE-DIPHOSPHA
TE-SUGAR EPIMERASE

(Staphylococcus
aureus) 		PF13460
(NAD_binding_10) 		4 VAL A 181
ILE A 185
VAL A  70
ILE A 104
 None
 0.73A 5bmvC-3e48A:
2.1		 5bmvC-3e48A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eo4 UNCHARACTERIZED
PROTEIN MJ1062

(Methanocaldococcus
jannaschii) 		PF13302
(Acetyltransf_3) 		5 VAL A 419
ASN A 420
ILE A 431
VAL A 453
ILE A 354
 None
MES  A   8 (-3.4A)
None
None
None
 1.46A 5bmvC-3eo4A:
undetectable		 5bmvC-3eo4A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fyf PROTEIN BVU-3222

(Bacteroides
vulgatus) 		PF14059
(DUF4251) 		4 VAL A  90
ILE A  99
VAL A 152
ILE A 154
 None
 0.69A 5bmvC-3fyfA:
undetectable		 5bmvC-3fyfA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0x 78 KDA
GLUCOSE-REGULATED
PROTEIN HOMOLOG

(Saccharomyces
cerevisiae) 		PF00012
(HSP70) 		4 VAL A 485
ILE A 446
VAL A 531
ILE A 546
 None
 0.66A 5bmvC-3h0xA:
undetectable		 5bmvC-3h0xA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hl0 MALEYLACETATE
REDUCTASE

(Agrobacterium
fabrum) 		PF00465
(Fe-ADH) 		4 VAL A  23
ILE A  27
VAL A  90
ILE A 115
 None
 0.73A 5bmvC-3hl0A:
2.7		 5bmvC-3hl0A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ift GLYCINE CLEAVAGE
SYSTEM H PROTEIN

(Mycobacterium
tuberculosis) 		PF01597
(GCV_H) 		4 PRO A  89
VAL A  92
ASN A  93
VAL A  61
 None
 0.77A 5bmvC-3iftA:
undetectable		 5bmvC-3iftA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iwk AMINOALDEHYDE
DEHYDROGENASE

(Pisum sativum) 		PF00171
(Aldedh) 		4 VAL A 345
ILE A 349
VAL A 375
ILE A 336
 None
 0.80A 5bmvC-3iwkA:
undetectable		 5bmvC-3iwkA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k4h PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Bacillus
cytotoxicus) 		PF13377
(Peripla_BP_3) 		5 VAL A  14
ILE A  73
PHE A  93
VAL A  61
ILE A  57
 None
 1.43A 5bmvC-3k4hA:
undetectable		 5bmvC-3k4hA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpp SUCRASE-ISOMALTASE

(Homo sapiens) 		PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N) 		4 ILE A 827
PHE A 842
VAL A 845
ILE A 847
 None
 0.77A 5bmvC-3lppA:
undetectable		 5bmvC-3lppA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lxu TRIPEPTIDYL-PEPTIDAS
E 2

(Drosophila
melanogaster) 		PF00082
(Peptidase_S8)
PF12580
(TPPII)
PF12583
(TPPII_N) 		4 VAL X 472
ILE X 476
VAL X 367
ILE X 394
 None
 0.78A 5bmvC-3lxuX:
undetectable		 5bmvC-3lxuX:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m05 UNCHARACTERIZED
PROTEIN PEPE_1480

(Pediococcus
pentosaceus) 		PF06153
(CdAMP_rec) 		4 VAL A  58
ILE A  62
VAL A   6
ILE A  50
 None
 0.76A 5bmvC-3m05A:
undetectable		 5bmvC-3m05A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mes CHOLINE KINASE

(Cryptosporidium
parvum) 		PF01633
(Choline_kinase) 		5 PRO A 103
ILE A 148
PHE A 107
VAL A  89
ILE A  91
 None
 1.20A 5bmvC-3mesA:
undetectable		 5bmvC-3mesA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n8e STRESS-70 PROTEIN,
MITOCHONDRIAL

(Homo sapiens) 		PF00012
(HSP70) 		4 VAL A 486
ILE A 447
VAL A 532
ILE A 547
 None
 0.67A 5bmvC-3n8eA:
undetectable		 5bmvC-3n8eA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n9i TRYPTOPHANYL-TRNA
SYNTHETASE

(Yersinia pestis) 		PF00579
(tRNA-synt_1b) 		4 PRO A 225
VAL A 228
ILE A 232
VAL A 293
 None
 0.71A 5bmvC-3n9iA:
undetectable		 5bmvC-3n9iA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nv0 NUCLEAR RNA EXPORT
FACTOR 2

(Caenorhabditis
elegans) 		no annotation 4 VAL A 216
ILE A 220
PHE A 320
VAL A 322
 None
 0.79A 5bmvC-3nv0A:
undetectable		 5bmvC-3nv0A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwn KINESIN-LIKE PROTEIN
KIF9

(Homo sapiens) 		PF00225
(Kinesin) 		4 VAL A 123
ILE A 127
VAL A 137
ILE A 222
 None
 0.73A 5bmvC-3nwnA:
undetectable		 5bmvC-3nwnA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oh8 NUCLEOSIDE-DIPHOSPHA
TE SUGAR EPIMERASE
(SULA FAMILY)

(Corynebacterium
glutamicum) 		PF01370
(Epimerase)
PF08338
(DUF1731) 		4 PRO A 488
VAL A 491
ILE A 495
VAL A  93
 None
 0.57A 5bmvC-3oh8A:
4.8		 5bmvC-3oh8A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3orq N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
SYNTHETASE

(Staphylococcus
aureus) 		PF02222
(ATP-grasp)
PF02826
(2-Hacid_dh_C) 		4 VAL A 238
ASN A 239
ILE A 242
VAL A 196
 None
 0.66A 5bmvC-3orqA:
undetectable		 5bmvC-3orqA:
22.67