SIMILAR PATTERNS OF AMINO ACIDS FOR 5B8I_C_FK5C201_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d0n HORSE PLASMA
GELSOLIN

(Equus caballus) 		PF00626
(Gelsolin) 		4 SER A 728
PRO A 727
PHE A 729
GLU A 725
 None
 1.23A 5b8iA-1d0nA:
undetectable		 5b8iA-1d0nA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d2k CHITINASE 1

(Coccidioides
immitis) 		PF00704
(Glyco_hydro_18) 		4 TRP A 245
SER A 242
PRO A 266
PHE A 241
 None
 1.21A 5b8iA-1d2kA:
0.2		 5b8iA-1d2kA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d7w MYELOPEROXIDASE

(Homo sapiens) 		PF03098
(An_peroxidase) 		4 SER C 368
PRO C 244
PHE C 366
GLU C 242
 None
None
None
HEM  A 605 (-2.1A)
 1.27A 5b8iA-1d7wC:
undetectable		 5b8iA-1d7wC:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eqn DNA PRIMASE

(Escherichia
coli) 		PF08275
(Toprim_N)
PF10410
(DnaB_bind)
PF13155
(Toprim_2) 		4 LEU A 407
SER A 369
PRO A 367
PHE A 371
 None
 1.20A 5b8iA-1eqnA:
0.1		 5b8iA-1eqnA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1imj CCG1-INTERACTING
FACTOR B

(Homo sapiens) 		PF12697
(Abhydrolase_6) 		4 LEU A  69
SER A 117
PRO A 119
PHE A 120
 None
 0.78A 5b8iA-1imjA:
undetectable		 5b8iA-1imjA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iv8 MALTOOLIGOSYL
TREHALOSE SYNTHASE

(Sulfolobus
acidocaldarius) 		PF00128
(Alpha-amylase)
PF09196
(DUF1953) 		4 SER A 458
PRO A 461
PHE A 460
GLU A 463
 None
None
MLY  A 558 ( 4.4A)
MLY  A 558 ( 3.0A)
 1.19A 5b8iA-1iv8A:
0.1		 5b8iA-1iv8A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j93 UROPORPHYRINOGEN
DECARBOXYLASE

(Nicotiana
tabacum) 		PF01208
(URO-D) 		4 LEU A 258
SER A 228
PRO A 230
PHE A 227
 None
 1.15A 5b8iA-1j93A:
undetectable		 5b8iA-1j93A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lzk HEROIN ESTERASE

(Rhodococcus sp.) 		PF07859
(Abhydrolase_3) 		4 SER A  98
PRO A 100
PHE A 101
GLU A 104
 None
 1.18A 5b8iA-1lzkA:
undetectable		 5b8iA-1lzkA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q32 TYROSYL-DNA
PHOSPHODIESTERASE

(Saccharomyces
cerevisiae) 		PF06087
(Tyr-DNA_phospho) 		4 LEU A 492
SER A 266
PRO A 232
PHE A 233
 None
 1.14A 5b8iA-1q32A:
undetectable		 5b8iA-1q32A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rp1 PANCREATIC LIPASE
RELATED PROTEIN 1

(Canis lupus) 		PF00151
(Lipase)
PF01477
(PLAT) 		4 LEU A 264
SER A 152
PRO A 177
GLU A 179
 None
 1.28A 5b8iA-1rp1A:
undetectable		 5b8iA-1rp1A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wql ETHYLBENZENE
DIOXYGENASE SMALL
SUBUNIT
IRON-SULFUR PROTEIN
LARGE SUBUNIT OF
CUMENE DIOXYGENASE

(Pseudomonas
fluorescens) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A)
PF00866
(Ring_hydroxyl_B) 		4 LEU A 254
SER A 247
PRO A 249
GLU B  85
 None
 1.22A 5b8iA-1wqlA:
undetectable		 5b8iA-1wqlA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wwr TRNA ADENOSINE
DEAMINASE TADA

(Aquifex
aeolicus) 		PF14437
(MafB19-deam) 		4 LEU A 139
SER A 100
PRO A 131
PHE A  99
 None
 1.30A 5b8iA-1wwrA:
undetectable		 5b8iA-1wwrA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x5e THIOREDOXIN DOMAIN
CONTAINING PROTEIN 1

(Homo sapiens) 		PF00085
(Thioredoxin) 		4 LEU A  21
SER A 121
PRO A 123
PHE A 120
 None
 1.22A 5b8iA-1x5eA:
undetectable		 5b8iA-1x5eA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xng NH(3)-DEPENDENT
NAD(+) SYNTHETASE

(Helicobacter
pylori) 		PF02540
(NAD_synthase) 		4 LEU A 224
PRO A 205
PHE A 160
GLU A 163
 None
 1.28A 5b8iA-1xngA:
undetectable		 5b8iA-1xngA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xrs D-LYSINE
5,6-AMINOMUTASE
ALPHA SUBUNIT

(Acetoanaerobium
sticklandii) 		PF09043
(Lys-AminoMut_A) 		4 LEU A   5
PRO A 365
PHE A 364
GLU A 321
 None
 1.02A 5b8iA-1xrsA:
undetectable		 5b8iA-1xrsA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yve ACETOHYDROXY ACID
ISOMEROREDUCTASE

(Spinacia
oleracea) 		PF01450
(IlvC)
PF07991
(IlvN) 		4 LEU I 144
SER I 295
PRO I 251
GLU I 311
 None
None
NDP  I 600 (-4.7A)
None
 1.30A 5b8iA-1yveI:
undetectable		 5b8iA-1yveI:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aj7 HYPOTHETICAL PROTEIN
BH3618

(Bacillus
halodurans) 		PF02623
(FliW) 		4 LEU A 139
SER A  66
PRO A  69
PHE A  65
 None
FMT  A 157 (-3.6A)
None
None
 0.99A 5b8iA-2aj7A:
undetectable		 5b8iA-2aj7A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i0z NAD(FAD)-UTILIZING
DEHYDROGENASES

(Bacillus cereus) 		PF03486
(HI0933_like) 		4 LEU A  41
PRO A 104
PHE A 103
GLU A  97
 None
 1.26A 5b8iA-2i0zA:
undetectable		 5b8iA-2i0zA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iqt FRUCTOSE-BISPHOSPHAT
E ALDOLASE CLASS 1

(Porphyromonas
gingivalis) 		PF00274
(Glycolytic) 		4 LEU A 107
PRO A 119
PHE A 120
GLU A 122
 None
 1.25A 5b8iA-2iqtA:
undetectable		 5b8iA-2iqtA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r8a LONG-CHAIN FATTY
ACID TRANSPORT
PROTEIN

(Escherichia
coli) 		PF03349
(Toluene_X) 		4 LEU A  68
SER A 116
PHE A 158
GLU A 156
 None
 1.27A 5b8iA-2r8aA:
undetectable		 5b8iA-2r8aA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA

(Desulfovibrio
vulgaris) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 SER A 169
PRO A 208
PHE A 210
GLU A 204
 None
 1.30A 5b8iA-2v4jA:
undetectable		 5b8iA-2v4jA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vbf BRANCHED-CHAIN
ALPHA-KETOACID
DECARBOXYLASE

(Lactococcus
lactis) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 LEU A 359
TRP A 360
SER A 380
PHE A 381
 LEU  A 359 ( 0.5A)
TRP  A 360 ( 0.5A)
SER  A 380 ( 0.0A)
PHE  A 381 ( 1.3A)
 1.29A 5b8iA-2vbfA:
undetectable		 5b8iA-2vbfA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xpz LEUKOTRIENE A-4
HYDROLASE

(Saccharomyces
cerevisiae) 		PF01433
(Peptidase_M1)
PF09127
(Leuk-A4-hydro_C) 		4 LEU A 394
SER A 408
PRO A 404
PHE A 407
 None
 1.27A 5b8iA-2xpzA:
undetectable		 5b8iA-2xpzA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z0v SH3-CONTAINING
GRB2-LIKE PROTEIN 3

(Homo sapiens) 		PF03114
(BAR) 		4 LEU A 135
SER A 177
PHE A 179
GLU A 183
 None
 1.23A 5b8iA-2z0vA:
undetectable		 5b8iA-2z0vA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3axi OLIGO-1,6-GLUCOSIDAS
E IMA1

(Saccharomyces
cerevisiae) 		PF00128
(Alpha-amylase) 		4 LEU A 226
PRO A 249
PHE A 254
GLU A 253
 None
 1.28A 5b8iA-3axiA:
undetectable		 5b8iA-3axiA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b89 16S RRNA METHYLASE

(Escherichia
coli) 		PF07091
(FmrO) 		4 LEU A 136
PRO A 142
PHE A 143
GLU A 146
 None
 1.22A 5b8iA-3b89A:
undetectable		 5b8iA-3b89A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b8i PA4872 OXALOACETATE
DECARBOXYLASE

(Pseudomonas
aeruginosa) 		PF13714
(PEP_mutase) 		4 LEU A 260
PRO A 272
PHE A 271
GLU A 274
 None
 1.29A 5b8iA-3b8iA:
undetectable		 5b8iA-3b8iA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddl XANTHORHODOPSIN

(Salinibacter
ruber) 		PF01036
(Bac_rhodopsin) 		4 LEU A 196
TRP A 200
PRO A 204
GLU A 141
 None
RET  A1301 (-3.9A)
RET  A1301 ( 4.2A)
RET  A1301 ( 3.8A)
 1.21A 5b8iA-3ddlA:
undetectable		 5b8iA-3ddlA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fr8 PUTATIVE KETOL-ACID
REDUCTOISOMERASE
(OS05G0573700
PROTEIN)

(Oryza sativa) 		PF01450
(IlvC)
PF07991
(IlvN) 		4 LEU A 144
SER A 295
PRO A 251
GLU A 311
 None
 1.26A 5b8iA-3fr8A:
undetectable		 5b8iA-3fr8A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gby UNCHARACTERIZED
PROTEIN CT1051

(Chlorobaculum
tepidum) 		PF00571
(CBS) 		4 SER A   5
PRO A  80
PHE A   4
GLU A  82
 None
EPE  A 127 (-3.9A)
None
EPE  A 127 (-4.5A)
 1.27A 5b8iA-3gbyA:
undetectable		 5b8iA-3gbyA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gxa OUTER MEMBRANE
LIPOPROTEIN GNA1946

(Neisseria
meningitidis) 		PF03180
(Lipoprotein_9) 		4 SER A 152
PRO A 151
PHE A 154
GLU A 194
 None
 1.28A 5b8iA-3gxaA:
undetectable		 5b8iA-3gxaA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ir1 OUTER MEMBRANE
LIPOPROTEIN GNA1946

(Neisseria
meningitidis) 		PF03180
(Lipoprotein_9) 		4 SER A 152
PRO A 151
PHE A 154
GLU A 194
 None
 1.28A 5b8iA-3ir1A:
undetectable		 5b8iA-3ir1A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kao TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE

(Staphylococcus
aureus) 		PF01791
(DeoC) 		4 SER A 195
PRO A 197
PHE A 199
GLU A 147
 None
 1.29A 5b8iA-3kaoA:
undetectable		 5b8iA-3kaoA:
21.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ll8 SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2B
CATALYTIC SUBUNIT
ALPHA ISOFORM

(Homo sapiens) 		PF00149
(Metallophos) 		5 LEU A 343
TRP A 352
SER A 353
PHE A 356
GLU A 359
 None
 0.83A 5b8iA-3ll8A:
56.7		 5b8iA-3ll8A:
73.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ll8 SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2B
CATALYTIC SUBUNIT
ALPHA ISOFORM

(Homo sapiens) 		PF00149
(Metallophos) 		5 LEU A 343
TRP A 352
SER A 353
PRO A 355
PHE A 356
 None
 0.52A 5b8iA-3ll8A:
56.7		 5b8iA-3ll8A:
73.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lmb UNCHARACTERIZED
PROTEIN

(Oleispira
antarctica) 		PF09500
(YiiD_C) 		4 LEU A  61
SER A 152
PRO A 151
GLU A 146
 None
 1.20A 5b8iA-3lmbA:
undetectable		 5b8iA-3lmbA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nks PROTOPORPHYRINOGEN
OXIDASE

(Homo sapiens) 		PF01593
(Amino_oxidase) 		4 LEU A 326
SER A 350
PRO A 354
PHE A 353
 None
 0.95A 5b8iA-3nksA:
undetectable		 5b8iA-3nksA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3orj SUGAR-BINDING
PROTEIN

(Bacteroides
ovatus) 		no annotation 4 TRP A 355
SER A 329
PHE A 331
GLU A 412
 None
 1.24A 5b8iA-3orjA:
undetectable		 5b8iA-3orjA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF16569
(GramPos_pilinBB)
PF16570
(GramPos_pilinD3) 		4 LEU A 256
TRP A 230
PHE A 231
GLU A 332
 None
 1.12A 5b8iA-3pf2A:
undetectable		 5b8iA-3pf2A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s9j MEMBER OF DUF4221
FAMILY

(Bacteroides
vulgatus) 		PF13970
(DUF4221) 		4 LEU A 197
SER A 112
PRO A 113
GLU A  61
 None
FMT  A 408 (-4.3A)
FMT  A 408 ( 4.4A)
GOL  A 418 (-3.7A)
 1.29A 5b8iA-3s9jA:
undetectable		 5b8iA-3s9jA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3shq UBLCP1

(Drosophila
melanogaster) 		PF00240
(ubiquitin)
PF03031
(NIF) 		4 LEU A 306
SER A 266
PRO A 264
PHE A 260
 None
 1.30A 5b8iA-3shqA:
undetectable		 5b8iA-3shqA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vqr PUTATIVE
OXIDOREDUCTASE

(Aeropyrum
pernix) 		PF01266
(DAO) 		4 LEU A 141
SER A 333
PRO A 337
PHE A 339
 None
 1.16A 5b8iA-3vqrA:
undetectable		 5b8iA-3vqrA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0k DNA DAMAGE-BINDING
PROTEIN 2

(Danio rerio) 		PF00400
(WD40) 		4 LEU D 450
SER D 144
PRO D 145
PHE D 447
 None
 1.17A 5b8iA-4a0kD:
undetectable		 5b8iA-4a0kD:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b2q ATP SYNTHASE SUBUNIT
BETA, MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 LEU D 217
SER D 182
PHE D 181
GLU D 247
 None
 0.93A 5b8iA-4b2qD:
undetectable		 5b8iA-4b2qD:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fsf PENICILLIN-BINDING
PROTEIN 3

(Pseudomonas
aeruginosa) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		4 LEU A 235
SER A 538
PRO A 540
PHE A 542
 None
 1.17A 5b8iA-4fsfA:
undetectable		 5b8iA-4fsfA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fyp VEGETATIVE STORAGE
PROTEIN 1

(Arabidopsis
thaliana) 		PF03767
(Acid_phosphat_B) 		4 LEU A 164
SER A 132
PRO A 134
GLU A 159
 None
 1.28A 5b8iA-4fypA:
undetectable		 5b8iA-4fypA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hq1 PROBABLE RECEPTOR
PROTEIN KINASE TMK1

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8) 		4 LEU A 214
PRO A 182
PHE A 185
GLU A 184
 None
None
None
FUC  A 505 (-3.5A)
 1.23A 5b8iA-4hq1A:
undetectable		 5b8iA-4hq1A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ifr 2-AMINO-3-CARBOXYMUC
ONATE 6-SEMIALDEHYDE
DECARBOXYLASE

(Pseudomonas
fluorescens) 		PF04909
(Amidohydro_2) 		5 LEU A  32
TRP A  58
PRO A  60
PHE A  62
GLU A  65
 None
 1.14A 5b8iA-4ifrA:
undetectable		 5b8iA-4ifrA:
21.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4il1 CALMODULIN,
CALCINEURIN SUBUNIT
B TYPE 1,
SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2B
CATALYTIC SUBUNIT
ALPHA ISOFORM

(Rattus
norvegicus) 		PF00149
(Metallophos)
PF13499
(EF-hand_7) 		6 LEU A 676
TRP A 685
SER A 686
PRO A 688
PHE A 689
GLU A 692
 None
 0.75A 5b8iA-4il1A:
52.8		 5b8iA-4il1A:
40.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4it7 CPI

(Ascaris
lumbricoides) 		PF00031
(Cystatin) 		4 LEU A  21
PRO A  97
PHE A 101
GLU A  99
 None
 1.14A 5b8iA-4it7A:
undetectable		 5b8iA-4it7A:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jjj CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Thermobifida
fusca) 		PF02011
(Glyco_hydro_48) 		4 LEU A 604
SER A 548
PRO A 547
GLU A  40
 None
ZN  A 735 (-3.9A)
None
CBK  A 702 ( 3.4A)
 1.17A 5b8iA-4jjjA:
undetectable		 5b8iA-4jjjA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ly4 PEPTIDOGLYCAN
DEACETYLASE

(Helicobacter
pylori) 		PF01522
(Polysacc_deac_1) 		4 LEU A 111
PRO A  70
PHE A  69
GLU A  40
 None
 1.28A 5b8iA-4ly4A:
undetectable		 5b8iA-4ly4A:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mg4 PHOSPHONOMUTASE

(Burkholderia
cenocepacia) 		PF13714
(PEP_mutase) 		4 LEU A 113
SER A 116
PRO A 118
PHE A 117
 None
 1.30A 5b8iA-4mg4A:
undetectable		 5b8iA-4mg4A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mnp N-ACETYLNEURAMINATE-
BINDING PROTEIN

(Fusobacterium
nucleatum) 		PF03480
(DctP) 		4 LEU A 139
PRO A 282
PHE A 283
GLU A 286
 None
 1.06A 5b8iA-4mnpA:
undetectable		 5b8iA-4mnpA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nkq GRANULOCYTE-MACROPHA
GE
COLONY-STIMULATING
FACTOR RECEPTOR
SUBUNIT ALPHA

(Homo sapiens) 		PF09240
(IL6Ra-bind) 		4 TRP B 287
SER B 288
PHE B 199
GLU B 197
 None
 1.27A 5b8iA-4nkqB:
undetectable		 5b8iA-4nkqB:
21.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ora SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2B
CATALYTIC SUBUNIT
BETA ISOFORM

(Homo sapiens) 		PF00149
(Metallophos) 		6 LEU A 352
TRP A 361
SER A 362
PRO A 364
PHE A 365
GLU A 368
 None
 0.72A 5b8iA-4oraA:
55.7		 5b8iA-4oraA:
52.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4orb SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2B
CATALYTIC SUBUNIT
ALPHA ISOFORM

(Mus musculus) 		PF00149
(Metallophos) 		6 LEU A 343
TRP A 352
SER A 353
PRO A 355
PHE A 356
GLU A 359
 None
 0.64A 5b8iA-4orbA:
55.9		 5b8iA-4orbA:
69.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ozd 14.4 KDA SALIVARY
PROTEIN

(Phlebotomus
duboscqi) 		PF01395
(PBP_GOBP) 		4 LEU A  21
SER A   4
PRO A   3
GLU A   1
 None
 1.27A 5b8iA-4ozdA:
undetectable		 5b8iA-4ozdA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxn UNCHARACTERIZED
PROTEIN

(Zea mays) 		PF00171
(Aldedh) 		4 LEU A 172
TRP A 188
SER A 221
GLU A  53
 None
 1.29A 5b8iA-4pxnA:
undetectable		 5b8iA-4pxnA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q88 UNCHARACTERIZED
PROTEIN

(Bacteroides
vulgatus) 		PF07470
(Glyco_hydro_88) 		4 TRP A  81
SER A  51
PHE A  52
GLU A 104
 None
 1.23A 5b8iA-4q88A:
undetectable		 5b8iA-4q88A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r89 UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF08774
(VRR_NUC) 		4 LEU A 262
SER A 286
PRO A 288
GLU A 323
 None
 1.21A 5b8iA-4r89A:
undetectable		 5b8iA-4r89A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rdc AMINO ACID/AMIDE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, HAAT FAMILY

(Trichormus
variabilis) 		PF13458
(Peripla_BP_6) 		4 LEU A 380
SER A 170
PRO A 172
GLU A 208
 None
 1.27A 5b8iA-4rdcA:
undetectable		 5b8iA-4rdcA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rs1 GRANULOCYTE-MACROPHA
GE
COLONY-STIMULATING
FACTOR RECEPTOR
SUBUNIT ALPHA

(Homo sapiens) 		PF09240
(IL6Ra-bind) 		4 TRP B 287
SER B 288
PHE B 199
GLU B 197
 None
 1.27A 5b8iA-4rs1B:
undetectable		 5b8iA-4rs1B:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4us5 LUCIFERASE-LIKE
MONOOXYGENASE

(Streptomyces
bottropensis) 		PF00296
(Bac_luciferase) 		4 LEU A 219
PRO A 280
PHE A 277
GLU A 275
 None
 1.20A 5b8iA-4us5A:
undetectable		 5b8iA-4us5A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4us5 LUCIFERASE-LIKE
MONOOXYGENASE

(Streptomyces
bottropensis) 		PF00296
(Bac_luciferase) 		4 LEU A 331
SER A   4
PHE A  39
GLU A   7
 None
None
None
NA  A1335 (-3.2A)
 1.23A 5b8iA-4us5A:
undetectable		 5b8iA-4us5A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v1r ALPHA-1,6-MANNANASE

(Bacteroides
thetaiotaomicron) 		PF03663
(Glyco_hydro_76) 		4 LEU A  87
SER A 377
PHE A 376
GLU A 359
 None
 1.13A 5b8iA-4v1rA:
undetectable		 5b8iA-4v1rA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wrl MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR

(Homo sapiens) 		PF00047
(ig) 		4 LEU A 148
SER A 139
PHE A 156
GLU A 135
 None
 1.07A 5b8iA-4wrlA:
undetectable		 5b8iA-4wrlA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wrm MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR

(Homo sapiens) 		PF00047
(ig)
PF13927
(Ig_3) 		4 LEU A 148
SER A 139
PHE A 156
GLU A 135
 None
 1.08A 5b8iA-4wrmA:
undetectable		 5b8iA-4wrmA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xru HEN1

(Capnocytophaga
gingivalis) 		no annotation 4 LEU C  15
SER C 160
PRO C 113
GLU C 157
 None
 1.29A 5b8iA-4xruC:
undetectable		 5b8iA-4xruC:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E

(Rattus
norvegicus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		4 LEU A 964
PRO A1263
PHE A1005
GLU A1261
 None
None
None
URC  A3007 (-2.9A)
 1.28A 5b8iA-4yswA:
undetectable		 5b8iA-4yswA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zb6 PCURE2P4

(Phanerochaete
chrysosporium) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 LEU A 151
SER A 172
PHE A 171
GLU A  28
 None
 1.10A 5b8iA-4zb6A:
undetectable		 5b8iA-4zb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zb8 PCURE2P6

(Phanerochaete
chrysosporium) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 LEU A 150
SER A 171
PHE A 170
GLU A  27
 None
 1.14A 5b8iA-4zb8A:
undetectable		 5b8iA-4zb8A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aee ALPHA-GLUCOSIDASE
YIHQ

(Escherichia
coli) 		PF01055
(Glyco_hydro_31) 		4 SER A 151
PRO A 183
PHE A 181
GLU A 134
 None
 1.13A 5b8iA-5aeeA:
undetectable		 5b8iA-5aeeA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dqf SERUM ALBUMIN

(Equus caballus) 		PF00273
(Serum_albumin) 		4 LEU A 345
SER A 219
PRO A 223
PHE A 222
 None
 1.30A 5b8iA-5dqfA:
undetectable		 5b8iA-5dqfA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ed1 DOUBLE-STRANDED
RNA-SPECIFIC EDITASE
1

(Homo sapiens) 		PF02137
(A_deamin) 		4 LEU A 323
SER A 543
PRO A 579
PHE A 542
 None
 1.10A 5b8iA-5ed1A:
undetectable		 5b8iA-5ed1A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hsi PUTATIVE
DECARBOXYLASE

(Lactobacillus
brevis) 		PF00282
(Pyridoxal_deC) 		4 LEU A 289
SER A 174
PRO A 176
PHE A 177
 None
 1.28A 5b8iA-5hsiA:
undetectable		 5b8iA-5hsiA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i5p TRAP TRANSPORTER
SOLUTE BINDING
PROTEIN

(uncultured
marine
bacterium) 		PF03480
(DctP) 		4 LEU A 140
TRP A  48
SER A  49
PRO A  47
 None
None
None
PEG  A 402 (-3.4A)
 1.19A 5b8iA-5i5pA:
undetectable		 5b8iA-5i5pA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Saccharomyces
cerevisiae) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 LEU B 850
PRO B1089
PHE B1087
GLU B1070
 None
 1.29A 5b8iA-5ip9B:
undetectable		 5b8iA-5ip9B:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j62 PUTATIVE REDUCTASE

(Clostridioides
difficile) 		PF00881
(Nitroreductase) 		4 LEU A 114
SER A  99
PRO A 188
PHE A  97
 None
 1.12A 5b8iA-5j62A:
undetectable		 5b8iA-5j62A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5joe TITIN

(Homo sapiens) 		PF07679
(I-set) 		4 LEU A  34
TRP A  36
PRO A  45
PHE A  49
 None
 0.88A 5b8iA-5joeA:
undetectable		 5b8iA-5joeA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jqk PEPTIDASE, PUTATIVE

(Plasmodium
falciparum) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
PF16188
(Peptidase_M24_C)
PF16189
(Creatinase_N_2) 		4 LEU A 354
SER A 369
PHE A 388
GLU A 414
 None
 1.21A 5b8iA-5jqkA:
undetectable		 5b8iA-5jqkA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k8f ACETYL-COENZYME A
SYNTHETASE

(Cryptococcus
neoformans) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N) 		4 LEU A 102
SER A 302
PRO A 283
PHE A 285
 None
 1.23A 5b8iA-5k8fA:
undetectable		 5b8iA-5k8fA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m30 TYPE VI SECRETION
PROTEIN

(Escherichia
coli) 		PF05936
(T6SS_VasE) 		4 LEU A  54
PRO A 182
PHE A 184
GLU A 296
 None
 0.83A 5b8iA-5m30A:
undetectable		 5b8iA-5m30A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mwn TYPE VI SECRETION
PROTEIN

(Escherichia
coli) 		PF05936
(T6SS_VasE) 		4 LEU A  54
PRO A 182
PHE A 184
GLU A 296
 None
 0.91A 5b8iA-5mwnA:
undetectable		 5b8iA-5mwnA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5okl AFAMIN

(Homo sapiens) 		no annotation 4 LEU A 349
SER A 223
PRO A 227
PHE A 226
 None
 1.19A 5b8iA-5oklA:
undetectable		 5b8iA-5oklA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tj6 HIGH CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL

(Aplysia
californica) 		PF00520
(Ion_trans)
PF03493
(BK_channel_a) 		4 LEU A 763
SER A 486
PRO A 490
PHE A 492
 None
 1.19A 5b8iA-5tj6A:
1.5		 5b8iA-5tj6A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7z ACID CERAMIDASE

(Homo sapiens) 		no annotation 4 LEU B 276
TRP B 248
PRO A 109
GLU A 115
 None
 1.10A 5b8iA-5u7zB:
undetectable		 5b8iA-5u7zB:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u8e ARGININE KINASE

(Polybetes
pythagoricus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 LEU A 275
SER A 260
PHE A 259
GLU A 254
 None
 1.30A 5b8iA-5u8eA:
undetectable		 5b8iA-5u8eA:
25.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uz5 U1 SMALL NUCLEAR
RIBONUCLEOPROTEIN
COMPONENT PRP42

(Saccharomyces
cerevisiae) 		no annotation 4 SER D 527
PRO D 530
PHE D 529
GLU D 532
 None
 0.95A 5b8iA-5uz5D:
undetectable		 5b8iA-5uz5D:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v3g PR DOMAIN ZINC
FINGER PROTEIN 9

(Homo sapiens) 		no annotation 4 TRP D 814
SER D 813
PRO D 802
PHE D 812
 None
 1.25A 5b8iA-5v3gD:
undetectable		 5b8iA-5v3gD:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7p OXAC

(Penicillium
oxalicum) 		no annotation 4 LEU A 140
SER A 136
PRO A 121
PHE A 135
 None
 1.30A 5b8iA-5w7pA:
undetectable		 5b8iA-5w7pA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w81 CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR

(Danio rerio) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane)
PF14396
(CFTR_R) 		4 LEU A 241
SER A 309
PHE A 312
GLU A 932
 None
 1.00A 5b8iA-5w81A:
undetectable		 5b8iA-5w81A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ydf PARAFIBROMIN

(Homo sapiens) 		no annotation 4 LEU A  57
SER A  31
PHE A  30
GLU A  29
 None
 1.18A 5b8iA-5ydfA:
undetectable		 5b8iA-5ydfA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yeu -

(-) 		no annotation 4 LEU A 283
SER A 242
PHE A 243
GLU A 363
 None
 1.15A 5b8iA-5yeuA:
undetectable		 5b8iA-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cip PYRUVATE-FERREDOXIN
OXIDOREDUCTASE

(Moorella
thermoacetica) 		no annotation 4 SER A 796
PRO A 790
PHE A 788
GLU A 727
 None
 1.27A 5b8iA-6cipA:
undetectable		 5b8iA-6cipA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cvz E3 UBIQUITIN-PROTEIN
LIGASE RFWD3

(Homo sapiens) 		no annotation 5 LEU A 588
SER A 616
PRO A 628
PHE A 617
GLU A 619
 None
 1.49A 5b8iA-6cvzA:
undetectable		 5b8iA-6cvzA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5z 24-STEROL
C-METHYLTRANSFERASE
UPF0434 FAMILY
PROTEIN

(Haloferax
volcanii) 		no annotation 4 LEU C  54
SER A  71
PHE A   7
GLU A   6
 None
None
SAH  A 301 (-3.5A)
None
 1.27A 5b8iA-6f5zC:
undetectable		 5b8iA-6f5zC:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4

(Mus musculus) 		no annotation 4 LEU M 457
SER M  62
PRO M  64
PHE M 110
 None
None
3PE  M 503 ( 4.6A)
None
 1.14A 5b8iA-6g2jM:
undetectable		 5b8iA-6g2jM:
11.14