SIMILAR PATTERNS OF AMINO ACIDS FOR 5AJQ_A_DB8A800_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c6v PROTEIN (SIV
INTEGRASE)

(Simian
immunodeficiency
virus) 		PF00665
(rve) 		4 VAL A 180
ILE A 162
ASN A 155
VAL A  73
 None
 1.27A 5ajqA-1c6vA:
undetectable		 5ajqA-1c6vA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d6t RIBONUCLEASE P

(Staphylococcus
aureus) 		PF00825
(Ribonuclease_P) 		4 VAL A  25
ILE A  18
ASN A  37
VAL A 111
 None
 1.32A 5ajqA-1d6tA:
undetectable		 5ajqA-1d6tA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ded CYCLODEXTRIN
GLUCANOTRANSFERASE

(Bacillus sp.
1011) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		4 VAL A 228
ILE A 215
ASN A 247
VAL A 252
 None
 1.02A 5ajqA-1dedA:
0.0		 5ajqA-1dedA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ecw GAG POLYPROTEIN

(Simian
immunodeficiency
virus) 		PF00540
(Gag_p17) 		4 VAL A  82
ILE A  88
ASN A  53
VAL A   7
 None
 1.23A 5ajqA-1ecwA:
undetectable		 5ajqA-1ecwA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE

(Homo sapiens) 		PF00884
(Sulfatase) 		4 VAL A 241
ILE A  67
ASN A 311
VAL A 329
 None
 1.32A 5ajqA-1fsuA:
0.0		 5ajqA-1fsuA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gu1 3-DEHYDROQUINATE
DEHYDRATASE

(Streptomyces
coelicolor) 		PF01220
(DHquinase_II) 		4 VAL A  63
ILE A  76
ASN A  95
VAL A 122
 None
 1.31A 5ajqA-1gu1A:
0.0		 5ajqA-1gu1A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hn0 CHONDROITIN ABC
LYASE I

(Proteus
vulgaris) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF09092
(Lyase_N)
PF09093
(Lyase_catalyt) 		4 VAL A 944
ILE A 979
ASN A 976
VAL A 992
 None
 1.20A 5ajqA-1hn0A:
0.3		 5ajqA-1hn0A:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hu3 EIF4GII

(Homo sapiens) 		PF02854
(MIF4G) 		4 VAL A 782
ILE A 792
ASN A 832
VAL A 817
 None
 1.27A 5ajqA-1hu3A:
undetectable		 5ajqA-1hu3A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ni3 YCHF GTP-BINDING
PROTEIN

(Schizosaccharomyces
pombe) 		PF01926
(MMR_HSR1)
PF06071
(YchF-GTPase_C) 		4 VAL A 138
ILE A 141
ASN A 243
VAL A 123
 None
 1.25A 5ajqA-1ni3A:
0.0		 5ajqA-1ni3A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oz7 ECHICETIN B-CHAIN

(Echis carinatus) 		PF00059
(Lectin_C) 		4 VAL B 118
ILE B  66
ASN B 101
VAL B  48
 None
 1.14A 5ajqA-1oz7B:
0.0		 5ajqA-1oz7B:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1phz PROTEIN
(PHENYLALANINE
HYDROXYLASE)

(Rattus
norvegicus) 		PF00351
(Biopterin_H)
PF01842
(ACT) 		4 VAL A 118
ILE A  38
ASN A 426
VAL A 412
 None
 1.26A 5ajqA-1phzA:
0.5		 5ajqA-1phzA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pox PYRUVATE OXIDASE

(Lactobacillus
plantarum) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 VAL A 149
ILE A 168
ASN A 127
VAL A 165
 None
 1.35A 5ajqA-1poxA:
undetectable		 5ajqA-1poxA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rj6 CARBONIC ANHYDRASE
XIV

(Mus musculus) 		PF00194
(Carb_anhydrase) 		4 VAL A 211
ILE A  31
ASN A 110
VAL A  38
 None
 1.20A 5ajqA-1rj6A:
undetectable		 5ajqA-1rj6A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1so8 3-HYDROXYACYL-COA
DEHYDROGENASE TYPE
II

(Homo sapiens) 		PF00106
(adh_short) 		4 VAL A  87
ILE A  15
ASN A 152
VAL A 128
 None
 1.22A 5ajqA-1so8A:
undetectable		 5ajqA-1so8A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tfe ELONGATION FACTOR TS

(Thermus
thermophilus) 		PF00889
(EF_TS) 		4 VAL A 108
ILE A 173
ASN A  77
VAL A  74
 None
 1.35A 5ajqA-1tfeA:
undetectable		 5ajqA-1tfeA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ujc PHOSPHOHISTIDINE
PHOSPHATASE SIXA

(Escherichia
coli) 		PF00300
(His_Phos_1) 		4 VAL A  43
ILE A 133
ASN A 147
VAL A   3
 None
 1.20A 5ajqA-1ujcA:
undetectable		 5ajqA-1ujcA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v02 DHURRINASE

(Sorghum bicolor) 		PF00232
(Glyco_hydro_1) 		4 VAL A 447
ILE A 387
ASN A 405
VAL A 436
 None
 1.23A 5ajqA-1v02A:
undetectable		 5ajqA-1v02A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vfg POLY A POLYMERASE

(Aquifex
aeolicus) 		PF01743
(PolyA_pol) 		4 VAL A  35
ILE A  15
ASN A 116
VAL A   2
 None
 1.33A 5ajqA-1vfgA:
undetectable		 5ajqA-1vfgA:
25.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wa3 2-KETO-3-DEOXY-6-PHO
SPHOGLUCONATE
ALDOLASE

(Thermotoga
maritima) 		PF01081
(Aldolase) 		4 VAL A 172
ILE A 200
ASN A 163
VAL A 177
 None
 1.30A 5ajqA-1wa3A:
undetectable		 5ajqA-1wa3A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140

(Agrobacterium
fabrum) 		PF02586
(SRAP) 		4 VAL A 120
ILE A 158
ASN A  99
VAL A 200
 None
 0.97A 5ajqA-2aegA:
undetectable		 5ajqA-2aegA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bb0 IMIDAZOLONEPROPIONAS
E

(Bacillus
subtilis) 		PF01979
(Amidohydro_1) 		4 VAL A 268
ILE A 365
ASN A 360
VAL A 292
 None
 1.26A 5ajqA-2bb0A:
undetectable		 5ajqA-2bb0A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsn PHOSPHODIESTERASE-NU
CLEOTIDE
PYROPHOSPHATASE

(Xanthomonas
citri) 		PF01663
(Phosphodiest) 		4 VAL A 184
ILE A  51
ASN A  68
VAL A 230
 None
 1.08A 5ajqA-2gsnA:
undetectable		 5ajqA-2gsnA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mk2 PHOSPHATIDYLINOSITOL
3,4,5-TRISPHOSPHATE
5-PHOSPHATASE 2

(Homo sapiens) 		PF00017
(SH2) 		4 VAL A  52
ILE A  91
ASN A  98
VAL A  73
 None
 1.07A 5ajqA-2mk2A:
undetectable		 5ajqA-2mk2A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2muy ATP-DEPENDENT ZINC
METALLOPROTEASE FTSH

(Escherichia
coli) 		PF06480
(FtsH_ext) 		4 VAL A  88
ILE A  56
ASN A  80
VAL A  46
 None
 1.31A 5ajqA-2muyA:
undetectable		 5ajqA-2muyA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nzt HEXOKINASE-2

(Homo sapiens) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 VAL A 393
ILE A 257
ASN A 235
VAL A  61
 None
None
GLC  A1001 (-3.6A)
UNX  A   4 (-4.1A)
 1.22A 5ajqA-2nztA:
undetectable		 5ajqA-2nztA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okv PROBABLE
D-TYROSYL-TRNA(TYR)
DEACYLASE 1

(Homo sapiens) 		PF02580
(Tyr_Deacylase) 		4 VAL A   5
ILE A  74
ASN A  51
VAL A  46
 MG  A1201 ( 4.9A)
None
None
None
 1.14A 5ajqA-2okvA:
undetectable		 5ajqA-2okvA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN

(Cupriavidus
pinatubonensis) 		PF02627
(CMD) 		4 VAL A  13
ILE A  27
ASN A 183
VAL A  40
 None
None
None
PEG  A 199 (-4.5A)
 1.32A 5ajqA-2prrA:
undetectable		 5ajqA-2prrA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pts ADENYLOSUCCINATE
LYASE

(Escherichia
coli) 		PF00206
(Lyase_1)
PF08328
(ASL_C) 		4 VAL A  12
ILE A 350
ASN A 345
VAL A 320
 None
 1.33A 5ajqA-2ptsA:
undetectable		 5ajqA-2ptsA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pts ADENYLOSUCCINATE
LYASE

(Escherichia
coli) 		PF00206
(Lyase_1)
PF08328
(ASL_C) 		4 VAL A 320
ILE A 350
ASN A 313
VAL A  12
 None
 1.23A 5ajqA-2ptsA:
undetectable		 5ajqA-2ptsA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q1w PUTATIVE NUCLEOTIDE
SUGAR EPIMERASE/
DEHYDRATASE

(Bordetella
bronchiseptica) 		PF01370
(Epimerase) 		4 VAL A  95
ILE A  55
ASN A  62
VAL A 101
 None
NAD  A 501 (-3.9A)
None
None
 1.34A 5ajqA-2q1wA:
undetectable		 5ajqA-2q1wA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ral SERINE-ASPARTATE
REPEAT-CONTAINING
PROTEIN G

(Staphylococcus
epidermidis) 		PF10425
(SdrG_C_C) 		4 VAL A 488
ILE A 453
ASN A 466
VAL A 526
 None
 1.16A 5ajqA-2ralA:
undetectable		 5ajqA-2ralA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL

(Homo sapiens) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 VAL A 111
ILE A 138
ASN A 268
VAL A 116
 None
 1.28A 5ajqA-2wd9A:
undetectable		 5ajqA-2wd9A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)

(Synechococcus
elongatus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 VAL A 310
ILE A 173
ASN A 170
VAL A 163
 None
 1.33A 5ajqA-3b20A:
undetectable		 5ajqA-3b20A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dmy PROTEIN FDRA

(Escherichia
coli) 		PF00549
(Ligase_CoA)
PF02629
(CoA_binding) 		4 VAL A 151
ILE A 123
ASN A 135
VAL A 170
 None
 1.27A 5ajqA-3dmyA:
undetectable		 5ajqA-3dmyA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e57 UNCHARACTERIZED
PROTEIN TM1382

(Thermotoga
maritima) 		PF00293
(NUDIX) 		4 VAL A   9
ILE A  58
ASN A 133
VAL A 142
 None
 1.31A 5ajqA-3e57A:
undetectable		 5ajqA-3e57A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ed3 PROTEIN
DISULFIDE-ISOMERASE
MPD1

(Saccharomyces
cerevisiae) 		PF00085
(Thioredoxin) 		4 VAL A 179
ILE A 163
ASN A 209
VAL A 235
 None
 1.26A 5ajqA-3ed3A:
undetectable		 5ajqA-3ed3A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fbt CHORISMATE MUTASE
AND SHIKIMATE
5-DEHYDROGENASE
FUSION PROTEIN

(Clostridium
acetobutylicum) 		PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		4 VAL A 274
ILE A 242
ASN A 237
VAL A 230
 None
 1.25A 5ajqA-3fbtA:
undetectable		 5ajqA-3fbtA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3feo MBT
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF02820
(MBT) 		4 VAL A  28
ILE A  43
ASN A  94
VAL A 148
 None
 1.33A 5ajqA-3feoA:
undetectable		 5ajqA-3feoA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k30 HISTAMINE
DEHYDROGENASE

(Pimelobacter
simplex) 		PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2) 		4 VAL A 298
ILE A 313
ASN A  27
VAL A  18
 None
 1.35A 5ajqA-3k30A:
undetectable		 5ajqA-3k30A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kcu PROBABLE FORMATE
TRANSPORTER 1

(Escherichia
coli) 		PF01226
(Form_Nir_trans) 		4 VAL A 149
ILE A 221
ASN A 213
VAL A 157
 None
 1.07A 5ajqA-3kcuA:
undetectable		 5ajqA-3kcuA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l0g NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE

(Ehrlichia
chaffeensis) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 VAL A  82
ILE A  98
ASN A  57
VAL A  63
 None
 0.89A 5ajqA-3l0gA:
undetectable		 5ajqA-3l0gA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mqt MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Shewanella
pealeana) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 VAL A  29
ILE A 102
ASN A  65
VAL A  70
 None
 1.08A 5ajqA-3mqtA:
undetectable		 5ajqA-3mqtA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mws HIV-1 PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 VAL A  13
ILE A  33
ASN A  88
VAL A  62
 None
 1.25A 5ajqA-3mwsA:
undetectable		 5ajqA-3mwsA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nku DRRA

(Legionella
pneumophila) 		no annotation 4 VAL A  94
ILE A 160
ASN A 134
VAL A 129
 None
 1.32A 5ajqA-3nkuA:
undetectable		 5ajqA-3nkuA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p5n RIBOFLAVIN UPTAKE
PROTEIN

(Staphylococcus
aureus) 		PF12822
(ECF_trnsprt) 		4 VAL A 134
ILE A 129
ASN A 164
VAL A 157
 None
None
RBF  A 190 (-3.3A)
None
 1.03A 5ajqA-3p5nA:
undetectable		 5ajqA-3p5nA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9h TUMOR SUSCEPTIBILITY
GENE 101 PROTEIN

(Homo sapiens) 		PF05743
(UEV) 		4 VAL A 141
ILE A  72
ASN A  69
VAL A  61
 None
 1.07A 5ajqA-3p9hA:
undetectable		 5ajqA-3p9hA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qfh EPIDERMIN LEADER
PEPTIDE PROCESSING
SERINE PROTEASE EPIP

(Staphylococcus
aureus) 		PF00082
(Peptidase_S8) 		4 VAL A 323
ILE A 230
ASN A 242
VAL A 245
 None
 1.30A 5ajqA-3qfhA:
undetectable		 5ajqA-3qfhA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r6k VP1 PROTEIN

(Norwalk virus) 		PF08435
(Calici_coat_C) 		4 VAL A 376
ILE A 368
ASN A 291
VAL A 294
 None
 1.31A 5ajqA-3r6kA:
undetectable		 5ajqA-3r6kA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rjy ENDOGLUCANASE
FNCEL5A

(Fervidobacterium
nodosum) 		PF00150
(Cellulase) 		4 VAL A 223
ILE A 164
ASN A 178
VAL A 216
 None
 1.08A 5ajqA-3rjyA:
undetectable		 5ajqA-3rjyA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3stg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE

(Neisseria
meningitidis) 		PF00793
(DAHP_synth_1) 		4 VAL A  17
ILE A   3
ASN A   6
VAL A 107
 None
 1.12A 5ajqA-3stgA:
undetectable		 5ajqA-3stgA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u1k POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE 1, MITOCHONDRIAL

(Homo sapiens) 		PF00013
(KH_1)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		4 VAL A 217
ILE A 134
ASN A 171
VAL A 188
 None
 1.34A 5ajqA-3u1kA:
undetectable		 5ajqA-3u1kA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vth HYDROGENASE
MATURATION FACTOR

(Caldanaerobacter
subterraneus) 		PF00708
(Acylphosphatase)
PF01300
(Sua5_yciO_yrdC)
PF07503
(zf-HYPF) 		4 VAL A  29
ILE A  16
ASN A  44
VAL A  23
 None
None
PO4  A 803 (-3.4A)
PO4  A 803 (-4.1A)
 1.07A 5ajqA-3vthA:
undetectable		 5ajqA-3vthA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wso F-BOX ONLY PROTEIN
44

(Homo sapiens) 		PF04300
(FBA)
PF12937
(F-box-like) 		4 VAL A 178
ILE A 158
ASN A  80
VAL A 139
 None
 1.31A 5ajqA-3wsoA:
0.5		 5ajqA-3wsoA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wt2 PROTEIN
DISULFIDE-ISOMERASE

(Humicola
insolens) 		PF00085
(Thioredoxin)
PF13848
(Thioredoxin_6) 		4 VAL A 392
ILE A 358
ASN A 344
VAL A 339
 None
 1.34A 5ajqA-3wt2A:
undetectable		 5ajqA-3wt2A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zpx LIPASE

(Ustilago maydis) 		PF03583
(LIP) 		4 VAL A 263
ILE A 290
ASN A 226
VAL A 238
 None
 1.35A 5ajqA-3zpxA:
0.0		 5ajqA-3zpxA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b60 FIBRONECTIN-BINDING
PROTEIN A

(Staphylococcus
aureus) 		PF10425
(SdrG_C_C) 		4 VAL A 217
ILE A 320
ASN A 252
VAL A 312
 None
 1.21A 5ajqA-4b60A:
undetectable		 5ajqA-4b60A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bbm CYCLIN-DEPENDENT
KINASE-LIKE 2

(Homo sapiens) 		PF00069
(Pkinase) 		4 VAL A  79
ILE A  29
ASN A   6
VAL A  10
 None
 1.15A 5ajqA-4bbmA:
23.9		 5ajqA-4bbmA:
28.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bhy ALANINE RACEMASE

(Aeromonas
hydrophila) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 VAL A 307
ILE A 293
ASN A 290
VAL A 322
 None
 1.18A 5ajqA-4bhyA:
undetectable		 5ajqA-4bhyA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cg4 PYRIN

(Homo sapiens) 		PF00622
(SPRY)
PF13765
(PRY) 		4 VAL A 691
ILE A 720
ASN A 733
VAL A 659
 None
 1.29A 5ajqA-4cg4A:
undetectable		 5ajqA-4cg4A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d7a TRNA
THREONYLCARBAMOYLADE
NOSINE DEHYDRATASE

(Escherichia
coli) 		PF00899
(ThiF) 		4 VAL A 125
ILE A 139
ASN A 145
VAL A 114
 None
 1.34A 5ajqA-4d7aA:
undetectable		 5ajqA-4d7aA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4efi 3-OXOACYL-(ACYL-CARR
IER PROTEIN)
SYNTHASE

(Paraburkholderia
xenovorans) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 VAL A 210
ILE A 161
ASN A 128
VAL A 336
 None
None
None
UNL  A 401 ( 4.9A)
 1.26A 5ajqA-4efiA:
undetectable		 5ajqA-4efiA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ell RETINOBLASTOMA-ASSOC
IATED PROTEIN

(Homo sapiens) 		PF01857
(RB_B)
PF01858
(RB_A) 		4 VAL A 493
ILE A 536
ASN A 541
VAL A 456
 None
 1.35A 5ajqA-4ellA:
undetectable		 5ajqA-4ellA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f9o HEXOKINASE-1

(Homo sapiens) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 VAL A 841
ILE A 705
ASN A 683
VAL A 509
 None
None
BGC  A1003 (-3.9A)
None
 1.24A 5ajqA-4f9oA:
undetectable		 5ajqA-4f9oA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g3t OXIDOREDUCTASE DPRE1

(Mycolicibacterium
smegmatis) 		PF01565
(FAD_binding_4)
PF04030
(ALO) 		4 VAL A 414
ILE A 358
ASN A 392
VAL A 395
 None
 1.31A 5ajqA-4g3tA:
undetectable		 5ajqA-4g3tA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k90 EXTRACELLULAR
METALLOPROTEINASE
MEP

(Aspergillus
fumigatus) 		PF07504
(FTP) 		4 VAL B 126
ILE B  78
ASN B 117
VAL B  46
 None
 1.14A 5ajqA-4k90B:
undetectable		 5ajqA-4k90B:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kk1 TUBEROUS SCLEROSIS 1
PROTEIN HOMOLOG

(Schizosaccharomyces
pombe) 		PF04388
(Hamartin) 		4 VAL A  75
ILE A  57
ASN A  12
VAL A   7
 None
 1.18A 5ajqA-4kk1A:
undetectable		 5ajqA-4kk1A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lry PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
DIHYDROXYACETONE-BIN
DING SUBUNIT DHAK

(Escherichia
coli) 		PF02733
(Dak1) 		4 VAL A 215
ILE A 187
ASN A 283
VAL A 150
 None
 1.22A 5ajqA-4lryA:
undetectable		 5ajqA-4lryA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m75 U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM1
U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM2

(Saccharomyces
cerevisiae) 		PF01423
(LSM) 		4 VAL B  17
ILE B  60
ASN B  37
VAL A 110
 None
 1.21A 5ajqA-4m75B:
undetectable		 5ajqA-4m75B:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mki ENERGY-COUPLING
FACTOR TRANSPORTER
ATP-BINDING PROTEIN
ECFA2

(Caldanaerobacter
subterraneus) 		no annotation 4 VAL B  76
ILE B  64
ASN B  67
VAL B  85
 None
 1.02A 5ajqA-4mkiB:
undetectable		 5ajqA-4mkiB:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mnp N-ACETYLNEURAMINATE-
BINDING PROTEIN

(Fusobacterium
nucleatum) 		PF03480
(DctP) 		4 VAL A  99
ILE A  89
ASN A  93
VAL A 305
 None
 1.31A 5ajqA-4mnpA:
undetectable		 5ajqA-4mnpA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4na3 POLYKETIDE SYNTHASE
PKSJ

(Bacillus
subtilis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 VAL A 502
ILE A 585
ASN A 460
VAL A 463
 None
 1.25A 5ajqA-4na3A:
undetectable		 5ajqA-4na3A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6x PHOSPHOLIPASE D
STSICTOX-BETAIC1

(Sicarius
terrosus) 		no annotation 4 VAL A 242
ILE A 228
ASN A   8
VAL A 256
 None
 1.34A 5ajqA-4q6xA:
undetectable		 5ajqA-4q6xA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiq D-XYLOSE-PROTON
SYMPORTER

(Escherichia
coli) 		PF00083
(Sugar_tr) 		4 VAL A 140
ILE A  69
ASN A 419
VAL A 412
 None
 1.28A 5ajqA-4qiqA:
undetectable		 5ajqA-4qiqA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4roa SERPIN 2

(Anopheles
gambiae) 		PF00079
(Serpin) 		4 VAL A 132
ILE A 189
ASN A 123
VAL A 151
 None
 1.20A 5ajqA-4roaA:
undetectable		 5ajqA-4roaA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wqm TOLUENE-4-MONOOXYGEN
ASE ELECTRON
TRANSFER COMPONENT

(Pseudomonas
mendocina) 		PF00111
(Fer2)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 VAL A 203
ILE A 320
ASN A 313
VAL A 305
 None
 1.17A 5ajqA-4wqmA:
undetectable		 5ajqA-4wqmA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x04 SOLUTE BINDING
PROTEIN

(Citrobacter
koseri) 		PF03480
(DctP) 		4 VAL A 291
ILE A 156
ASN A 222
VAL A 226
 None
 1.28A 5ajqA-4x04A:
undetectable		 5ajqA-4x04A:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x54 OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY

(Brucella ovis) 		PF13561
(adh_short_C2) 		4 VAL A  77
ILE A  89
ASN A 108
VAL A  30
 None
 1.09A 5ajqA-4x54A:
undetectable		 5ajqA-4x54A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhj ENVELOPE
GLYCOPROTEIN H

(Human
alphaherpesvirus
3) 		PF02489
(Herpes_glycop_H)
PF17488
(Herpes_glycoH_C) 		4 VAL A 696
ILE A 693
ASN A 674
VAL A 658
 None
 1.17A 5ajqA-4xhjA:
undetectable		 5ajqA-4xhjA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yj5 PYRUVATE KINASE PKM

(Homo sapiens) 		PF00224
(PK)
PF02887
(PK_C) 		4 VAL A 511
ILE A 451
ASN A 491
VAL A 530
 None
 1.17A 5ajqA-4yj5A:
undetectable		 5ajqA-4yj5A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zm4 AMINOTRANSFERASE

(Streptomyces
pactum) 		PF00202
(Aminotran_3) 		4 VAL A  41
ILE A  57
ASN A  61
VAL A  35
 None
 1.32A 5ajqA-4zm4A:
undetectable		 5ajqA-4zm4A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE

(Sulfolobus
acidocaldarius) 		no annotation 4 VAL A  91
ILE A 229
ASN A 175
VAL A 156
 None
 1.28A 5ajqA-5a7tA:
undetectable		 5ajqA-5a7tA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ap9 LIPASE

(Thermomyces
lanuginosus) 		PF01764
(Lipase_3)
PF03893
(Lipase3_N) 		4 VAL A   2
ILE A 196
ASN A  11
VAL A 230
 None
 1.31A 5ajqA-5ap9A:
undetectable		 5ajqA-5ap9A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c0s HEMAGGLUTININ,
ENVELOPE
GLYCOPROTEIN,
FIBRITIN FUSION
PROTEIN

(Escherichia
virus T4;
Human
immunodeficiency
virus 1;
Influenza A
virus) 		PF00509
(Hemagglutinin)
PF07921
(Fibritin_C) 		4 VAL A 103
ILE A  96
ASN A 186
VAL A  30
 None
 1.24A 5ajqA-5c0sA:
undetectable		 5ajqA-5c0sA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cdh MAJOR ACID
PHOSPHATASE

(Legionella
pneumophila) 		PF00328
(His_Phos_2) 		4 VAL A 287
ILE A 321
ASN A 304
VAL A  29
 None
None
1PE  A 405 (-3.6A)
None
 1.33A 5ajqA-5cdhA:
undetectable		 5ajqA-5cdhA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cjf CARBONIC ANHYDRASE
14

(Homo sapiens) 		PF00194
(Carb_anhydrase) 		4 VAL A 211
ILE A  31
ASN A 110
VAL A  38
 None
 1.30A 5ajqA-5cjfA:
undetectable		 5ajqA-5cjfA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cjs DESIGNED INFLUENZA
HEMAGGLUTININ STEM
#4454, HA1
DESIGNED INFLUENZA
HEMAGGLUTININ STEM
#4454, HA2

(synthetic
construct) 		PF00509
(Hemagglutinin) 		4 VAL D  55
ILE D  48
ASN D 104
VAL C  40
 None
 1.17A 5ajqA-5cjsD:
undetectable		 5ajqA-5cjsD:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e3v ADENYLOSUCCINATE
LYASE

(Salmonella
enterica) 		PF00206
(Lyase_1)
PF08328
(ASL_C) 		4 VAL A  12
ILE A 350
ASN A 345
VAL A 320
 None
 1.30A 5ajqA-5e3vA:
undetectable		 5ajqA-5e3vA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5euh PUTATIVE GGDEF
DOMAIN MEMBRANE
PROTEIN

(Pseudomonas
fluorescens) 		PF00990
(GGDEF) 		4 VAL A 498
ILE A 376
ASN A 407
VAL A 446
 None
 1.07A 5ajqA-5euhA:
undetectable		 5ajqA-5euhA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k0u CAPSID PROTEIN VP1
CAPSID PROTEIN VP2

(Rhinovirus C) 		PF00073
(Rhv) 		4 VAL A 233
ILE C 127
ASN C 222
VAL C 206
 None
 1.21A 5ajqA-5k0uA:
undetectable		 5ajqA-5k0uA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k9o HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 VAL F 384
ILE F 377
ASN F 433
VAL F  40
 None
 1.16A 5ajqA-5k9oF:
undetectable		 5ajqA-5k9oF:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kp9 EPN-01*

(Human
immunodeficiency
virus 1;
Thermotoga
maritima) 		PF01081
(Aldolase) 		4 VAL B 170
ILE B 198
ASN B 161
VAL B 175
 None
 1.26A 5ajqA-5kp9B:
undetectable		 5ajqA-5kp9B:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l2q SERINE/THREONINE-PRO
TEIN KINASE 40

(Homo sapiens) 		no annotation 4 VAL C 263
ILE C 177
ASN C 158
VAL C 163
 None
 1.21A 5ajqA-5l2qC:
21.4		 5ajqA-5l2qC:
27.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ncl CBK1 KINASE
ACTIVATOR PROTEIN
MOB2

(Saccharomyces
cerevisiae) 		no annotation 4 VAL B 148
ILE B 229
ASN B 138
VAL B 143
 None
 1.11A 5ajqA-5nclB:
undetectable		 5ajqA-5nclB:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri) 		no annotation 4 VAL A 609
ILE A 555
ASN A 544
VAL A 620
 None
 1.09A 5ajqA-5ny0A:
undetectable		 5ajqA-5ny0A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oom 39S RIBOSOMAL
PROTEIN L43,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 4 VAL b  47
ILE b  63
ASN b  66
VAL b  75
 None
 1.32A 5ajqA-5oomb:
undetectable		 5ajqA-5oomb:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ujz HEMAGGLUTININ HA1
HEMAGGLUTININ HA2

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 VAL B 555
ILE B 548
ASN B 604
VAL A  34
 None
 0.93A 5ajqA-5ujzB:
undetectable		 5ajqA-5ujzB:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r X-RAY REPAIR
CROSS-COMPLEMENTING
PROTEIN 6

(Homo sapiens) 		PF02735
(Ku)
PF03730
(Ku_C)
PF03731
(Ku_N) 		4 VAL A  86
ILE A 166
ASN A 152
VAL A 146
 None
 1.34A 5ajqA-5y3rA:
undetectable		 5ajqA-5y3rA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z2e DIHYDRODIPICOLINATE
REDUCTASE

(Paenisporosarcina
sp. TG-14) 		no annotation 4 VAL A  71
ILE A   6
ASN A  24
VAL A 243
 None
 1.09A 5ajqA-5z2eA:
undetectable		 5ajqA-5z2eA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zfh KALLIKREIN-7

(Mus musculus) 		no annotation 4 VAL A 171
ILE A 163
ASN A 189
VAL A 227
 None
 1.21A 5ajqA-5zfhA:
undetectable		 5ajqA-5zfhA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d8w HEMAGGLUTININ

(Influenza A
virus) 		no annotation 4 VAL A 384
ILE A 377
ASN A 433
VAL A  32
 None
 1.31A 5ajqA-6d8wA:
undetectable		 5ajqA-6d8wA:
17.00