SIMILAR PATTERNS OF AMINO ACIDS FOR 5AGK_A_H4BA760
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c4k | PROTEIN (ORNITHINEDECARBOXYLASE) (Lactobacillussp. 30A) |
PF01276(OKR_DC_1)PF03709(OKR_DC_1_N)PF03711(OKR_DC_1_C) | 4 | VAL A 667TRP A 673PHE A 681GLU A 649 | None | 1.35A | 5agkA-1c4kA:0.05agkB-1c4kA:0.0 | 5agkA-1c4kA:19.075agkB-1c4kA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dvk | PRP18 (Saccharomycescerevisiae) |
PF02840(Prp18) | 4 | ARG A 123TRP A 242PHE A 239GLU A 241 | None | 1.48A | 5agkA-1dvkA:1.75agkB-1dvkA:2.1 | 5agkA-1dvkA:17.185agkB-1dvkA:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fhu | O-SUCCINYLBENZOATESYNTHASE (Escherichiacoli) |
PF13378(MR_MLE_C) | 4 | ARG A 2VAL A 87TRP A 66GLU A 76 | None | 1.49A | 5agkA-1fhuA:0.05agkB-1fhuA:0.8 | 5agkA-1fhuA:25.235agkB-1fhuA:25.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1flg | PROTEIN(QUINOPROTEINETHANOLDEHYDROGENASE) (Pseudomonasaeruginosa) |
PF01011(PQQ)PF13360(PQQ_2) | 4 | VAL A 41TRP A 521PHE A 501GLU A 519 | None | 1.22A | 5agkA-1flgA:0.05agkB-1flgA:0.0 | 5agkA-1flgA:19.675agkB-1flgA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h2t | 80 KDA NUCLEAR CAPBINDING PROTEIN (Homo sapiens) |
PF02854(MIF4G)PF09088(MIF4G_like)PF09090(MIF4G_like_2) | 4 | MET C 291VAL C 216PHE C 360GLU C 353 | None | 1.28A | 5agkA-1h2tC:0.05agkB-1h2tC:0.0 | 5agkA-1h2tC:19.485agkB-1h2tC:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kex | NEUROPILIN-1 (Homo sapiens) |
PF00754(F5_F8_type_C) | 4 | ARG A 130TRP A 97PHE A 131GLU A 95 | None | 1.44A | 5agkA-1kexA:undetectable5agkB-1kexA:0.0 | 5agkA-1kexA:16.835agkB-1kexA:16.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kh2 | ARGININOSUCCINATESYNTHETASE (Thermusthermophilus) |
PF00764(Arginosuc_synth) | 4 | ARG A 282VAL A 226PHE A 220GLU A 222 | None | 1.35A | 5agkA-1kh2A:0.05agkB-1kh2A:0.1 | 5agkA-1kh2A:22.655agkB-1kh2A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l5j | ACONITATE HYDRATASE2 (Escherichiacoli) |
PF00330(Aconitase)PF06434(Aconitase_2_N)PF11791(Aconitase_B_N) | 4 | ARG A 340TRP A 155PHE A 156GLU A 154 | None | 1.34A | 5agkA-1l5jA:0.05agkB-1l5jA:0.0 | 5agkA-1l5jA:19.285agkB-1l5jA:19.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lzx | NITRIC-OXIDESYNTHASE (Rattusnorvegicus) |
PF02898(NO_synthase) | 4 | MET A 336ARG A 596VAL A 677TRP A 678 | H4B A 760 ( 3.8A)H4B A 760 (-3.5A)H4B A 760 (-4.6A)H4B A 760 ( 3.6A) | 0.43A | 5agkA-1lzxA:63.55agkB-1lzxA:62.6 | 5agkA-1lzxA:100.005agkB-1lzxA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mhz | METHANEMONOOXYGENASEHYDROXYLASE (Methylosinustrichosporium) |
PF02332(Phenol_Hydrox) | 4 | VAL D 28TRP D 31PHE D 35GLU D 132 | None | 1.40A | 5agkA-1mhzD:undetectable5agkB-1mhzD:undetectable | 5agkA-1mhzD:20.855agkB-1mhzD:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mns | MANDELATE RACEMASE (Pseudomonasputida) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ARG A 318VAL A 163PHE A 160GLU A 157 | None | 1.40A | 5agkA-1mnsA:undetectable5agkB-1mnsA:0.7 | 5agkA-1mnsA:21.595agkB-1mnsA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mzb | FERRIC UPTAKEREGULATION PROTEIN (Pseudomonasaeruginosa) |
PF01475(FUR) | 4 | ARG A 69VAL A 54PHE A 79GLU A 36 | None | 1.01A | 5agkA-1mzbA:undetectable5agkB-1mzbA:2.3 | 5agkA-1mzbA:16.595agkB-1mzbA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pdu | NUCLEAR HORMONERECEPTOR HR38 (Drosophilamelanogaster) |
PF00104(Hormone_recep) | 4 | MET A 440VAL A 401TRP A 435PHE A 432 | None | 1.00A | 5agkA-1pduA:undetectable5agkB-1pduA:undetectable | 5agkA-1pduA:21.055agkB-1pduA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rhc | F420-DEPENDENTALCOHOLDEHYDROGENASE (Methanoculleusthermophilus) |
PF00296(Bac_luciferase) | 4 | MET A 282VAL A 232PHE A 321GLU A 293 | None | 1.43A | 5agkA-1rhcA:undetectable5agkB-1rhcA:0.1 | 5agkA-1rhcA:20.145agkB-1rhcA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t1j | HYPOTHETICAL PROTEIN (Pseudomonasaeruginosa) |
PF09152(DUF1937) | 4 | ARG A 2VAL A 28TRP A 110PHE A 117 | None | 1.48A | 5agkA-1t1jA:undetectable5agkB-1t1jA:undetectable | 5agkA-1t1jA:16.385agkB-1t1jA:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tki | TITIN (Homo sapiens) |
PF00069(Pkinase) | 4 | VAL A 122TRP A 277PHE A 254GLU A 250 | None | 1.50A | 5agkA-1tkiA:undetectable5agkB-1tkiA:undetectable | 5agkA-1tkiA:20.235agkB-1tkiA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vmk | PURINE NUCLEOSIDEPHOSPHORYLASE (Thermotogamaritima) |
PF01048(PNP_UDP_1) | 4 | VAL A 221TRP A 162PHE A 265GLU A 161 | None | 1.43A | 5agkA-1vmkA:undetectable5agkB-1vmkA:undetectable | 5agkA-1vmkA:21.485agkB-1vmkA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wf0 | TAR DNA-BINDINGPROTEIN-43 (Homo sapiens) |
PF00076(RRM_1) | 4 | MET A 17VAL A 35PHE A 26GLU A 21 | None | 1.08A | 5agkA-1wf0A:undetectable5agkB-1wf0A:undetectable | 5agkA-1wf0A:11.855agkB-1wf0A:11.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wql | ETHYLBENZENEDIOXYGENASE SMALLSUBUNIT (Pseudomonasfluorescens) |
PF00866(Ring_hydroxyl_B) | 4 | ARG B 156VAL B 128PHE B 163GLU B 26 | None | 1.13A | 5agkA-1wqlB:undetectable5agkB-1wqlB:undetectable | 5agkA-1wqlB:19.795agkB-1wqlB:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b39 | C3 (Bos taurus) |
PF00207(A2M)PF01759(NTR)PF01821(ANATO)PF01835(A2M_N)PF07677(A2M_recep)PF07678(A2M_comp)PF07703(A2M_N_2)PF10569(Thiol-ester_cl) | 4 | ARG A 708VAL A1424PHE A 722GLU A 693 | None | 1.07A | 5agkA-2b39A:undetectable5agkB-2b39A:2.3 | 5agkA-2b39A:13.585agkB-2b39A:13.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b4x | ANTITHROMBIN-III (Homo sapiens) |
PF00079(Serpin) | 4 | VAL I 375TRP I 225PHE I 274GLU I 378 | None | 1.49A | 5agkA-2b4xI:undetectable5agkB-2b4xI:undetectable | 5agkA-2b4xI:22.015agkB-2b4xI:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fja | ADENYLYLSULFATEREDUCTASE, SUBUNIT AADENYLYLSULFATEREDUCTASE, SUBUNIT B (Archaeoglobusfulgidus) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C)PF12139(APS-reductase_C)PF13187(Fer4_9) | 4 | ARG A 62VAL A 367TRP B 788GLU A 360 | None | 1.34A | 5agkA-2fjaA:undetectable5agkB-2fjaA:undetectable | 5agkA-2fjaA:22.295agkB-2fjaA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vy0 | ENDO-BETA-1,3-GLUCANASE (Pyrococcusfuriosus) |
PF00722(Glyco_hydro_16) | 4 | VAL A 245TRP A 252PHE A 254GLU A 251 | NoneNoneNoneMRD A1301 (-4.3A) | 1.42A | 5agkA-2vy0A:undetectable5agkB-2vy0A:undetectable | 5agkA-2vy0A:20.005agkB-2vy0A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w4o | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE TYPE IV (Homo sapiens) |
PF00069(Pkinase) | 4 | ARG A 278VAL A 269TRP A 266PHE A 261 | None | 1.43A | 5agkA-2w4oA:undetectable5agkB-2w4oA:undetectable | 5agkA-2w4oA:20.265agkB-2w4oA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xhy | 6-PHOSPHO-BETA-GLUCOSIDASE BGLA (Escherichiacoli) |
PF00232(Glyco_hydro_1) | 4 | ARG A 159VAL A 164PHE A 98GLU A 108 | None | 1.48A | 5agkA-2xhyA:undetectable5agkB-2xhyA:undetectable | 5agkA-2xhyA:20.635agkB-2xhyA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xvg | ALPHA XYLOSIDASE (Cellvibriojaponicus) |
PF01055(Glyco_hydro_31)PF16338(DUF4968)PF17137(DUF5110) | 4 | ARG A 697VAL A 717PHE A 698GLU A 722 | None | 1.30A | 5agkA-2xvgA:undetectable5agkB-2xvgA:undetectable | 5agkA-2xvgA:19.685agkB-2xvgA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ywb | GMP SYNTHASE[GLUTAMINE-HYDROLYZING] (Thermusthermophilus) |
PF00117(GATase)PF00958(GMP_synt_C) | 4 | ARG A 211VAL A 239PHE A 309GLU A 305 | None | 1.31A | 5agkA-2ywbA:undetectable5agkB-2ywbA:undetectable | 5agkA-2ywbA:21.545agkB-2ywbA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z11 | RIBOSOMAL-PROTEIN-ALANINEACETYLTRANSFERASE (Thermusthermophilus) |
PF13302(Acetyltransf_3) | 4 | VAL A 64TRP A 66PHE A 4GLU A 6 | None | 1.44A | 5agkA-2z11A:undetectable5agkB-2z11A:undetectable | 5agkA-2z11A:17.585agkB-2z11A:17.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b7f | GLYCOSYL HYDROLASE,BNR REPEAT (Cupriaviduspinatubonensis) |
no annotation | 4 | VAL A 314TRP A 293TRP A 374GLU A 372 | NoneNoneNoneEDO A 404 ( 3.8A) | 1.41A | 5agkA-3b7fA:undetectable5agkB-3b7fA:undetectable | 5agkA-3b7fA:20.875agkB-3b7fA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bit | FACT COMPLEX SUBUNITSPT16 (Saccharomycescerevisiae) |
PF00557(Peptidase_M24)PF14826(FACT-Spt16_Nlob) | 4 | ARG A 105VAL A 35TRP A 147PHE A 117 | None | 1.49A | 5agkA-3bitA:undetectable5agkB-3bitA:undetectable | 5agkA-3bitA:23.515agkB-3bitA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d2w | TAR DNA-BINDINGPROTEIN 43 (Mus musculus) |
PF00076(RRM_1) | 4 | MET A 202VAL A 220PHE A 211GLU A 206 | None | 0.98A | 5agkA-3d2wA:undetectable5agkB-3d2wA:undetectable | 5agkA-3d2wA:12.225agkB-3d2wA:12.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ddl | XANTHORHODOPSIN (Salinibacterruber) |
PF01036(Bac_rhodopsin) | 4 | VAL A 16TRP A 70PHE A 88GLU A 71 | None | 1.47A | 5agkA-3ddlA:undetectable5agkB-3ddlA:2.0 | 5agkA-3ddlA:20.145agkB-3ddlA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gs3 | SYMPLEKIN (Drosophilamelanogaster) |
PF11935(DUF3453) | 4 | ARG A 27VAL A 56PHE A 67GLU A 65 | None | 1.50A | 5agkA-3gs3A:undetectable5agkB-3gs3A:undetectable | 5agkA-3gs3A:20.285agkB-3gs3A:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gyx | ADENYLYLSULFATEREDUCTASE (Desulfovibriogigas) |
PF00890(FAD_binding_2)PF12139(APS-reductase_C)PF13187(Fer4_9) | 4 | ARG A 66VAL A 387TRP B 88GLU A 380 | None | 1.28A | 5agkA-3gyxA:undetectable5agkB-3gyxA:2.7 | 5agkA-3gyxA:20.985agkB-3gyxA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ma6 | CALMODULIN-DOMAINPROTEIN KINASE 1 (Toxoplasmagondii) |
PF00069(Pkinase) | 4 | ARG A 269VAL A 260TRP A 257PHE A 252 | None | 1.43A | 5agkA-3ma6A:undetectable5agkB-3ma6A:undetectable | 5agkA-3ma6A:21.555agkB-3ma6A:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n3k | UBIQUITINCARBOXYL-TERMINALHYDROLASE 8 (Homo sapiens) |
PF00443(UCH) | 4 | ARG A 944TRP A1001PHE A 946GLU A 908 | None | 1.45A | 5agkA-3n3kA:undetectable5agkB-3n3kA:undetectable | 5agkA-3n3kA:19.835agkB-3n3kA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nkz | FLAGELLAR PROTEINFLIT (Yersiniaenterocolitica) |
PF05400(FliT) | 4 | MET A 38ARG A 69VAL A 44GLU A 37 | NoneNonePG4 A 122 ( 4.2A)None | 1.34A | 5agkA-3nkzA:undetectable5agkB-3nkzA:2.6 | 5agkA-3nkzA:15.335agkB-3nkzA:15.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3owc | PROBABLEACETYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00583(Acetyltransf_1) | 4 | ARG A 175VAL A 92PHE A 121GLU A 119 | None | 1.23A | 5agkA-3owcA:undetectable5agkB-3owcA:1.6 | 5agkA-3owcA:16.475agkB-3owcA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rjy | ENDOGLUCANASEFNCEL5A (Fervidobacteriumnodosum) |
PF00150(Cellulase) | 4 | VAL A 149TRP A 146PHE A 162GLU A 187 | None | 1.29A | 5agkA-3rjyA:undetectable5agkB-3rjyA:1.3 | 5agkA-3rjyA:21.275agkB-3rjyA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ti8 | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | VAL A 240TRP A 239PHE A 305GLU A 265 | None | 1.44A | 5agkA-3ti8A:undetectable5agkB-3ti8A:undetectable | 5agkA-3ti8A:22.645agkB-3ti8A:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqu | NON-CANONICAL PURINENTP PYROPHOSPHATASE (Coxiellaburnetii) |
PF01725(Ham1p_like) | 4 | VAL A 162TRP A 140PHE A 118GLU A 141 | None | 1.26A | 5agkA-3tquA:undetectable5agkB-3tquA:undetectable | 5agkA-3tquA:19.055agkB-3tquA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uxm | THYMIDYLATE KINASE (Pseudomonasaeruginosa) |
PF02223(Thymidylate_kin) | 4 | ARG A 109VAL A 166PHE A 162GLU A 156 | NoneNoneNone MG A 213 (-3.2A) | 1.32A | 5agkA-3uxmA:undetectable5agkB-3uxmA:undetectable | 5agkA-3uxmA:20.295agkB-3uxmA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fnq | ALPHA-GALACTOSIDASEAGAB (Geobacillusstearothermophilus) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 4 | ARG A 373VAL A 412TRP A 383PHE A 370 | None | 1.50A | 5agkA-4fnqA:undetectable5agkB-4fnqA:undetectable | 5agkA-4fnqA:20.735agkB-4fnqA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g76 | PHOSPHODIESTERASE (Pseudomonasaeruginosa) |
PF14859(Colicin_M) | 4 | MET A 258VAL A 265TRP A 62PHE A 85 | None | 1.31A | 5agkA-4g76A:undetectable5agkB-4g76A:undetectable | 5agkA-4g76A:19.865agkB-4g76A:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l37 | ARYLPHORIN (Bombyx mori) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 4 | VAL B 351TRP B 355PHE B 327GLU B 424 | None | 1.08A | 5agkA-4l37B:undetectable5agkB-4l37B:undetectable | 5agkA-4l37B:20.695agkB-4l37B:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pne | METHYLTRANSFERASE-LIKE PROTEIN (Saccharopolysporaspinosa) |
PF08241(Methyltransf_11) | 4 | ARG A 75VAL A 79PHE A 141GLU A 162 | None | 1.30A | 5agkA-4pneA:undetectable5agkB-4pneA:undetectable | 5agkA-4pneA:21.365agkB-4pneA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xj6 | VC0179-LIKE PROTEIN (Escherichiacoli) |
no annotation | 4 | ARG A 276VAL A 305PHE A 264GLU A 266 | None | 1.17A | 5agkA-4xj6A:undetectable5agkB-4xj6A:undetectable | 5agkA-4xj6A:21.065agkB-4xj6A:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xj6 | VC0179-LIKE PROTEIN (Escherichiacoli) |
no annotation | 4 | VAL A 305TRP A 263PHE A 264GLU A 266 | None | 1.08A | 5agkA-4xj6A:undetectable5agkB-4xj6A:undetectable | 5agkA-4xj6A:21.065agkB-4xj6A:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ylr | TUBULINPOLYGLUTAMYLASETTLL7 (Homo sapiens) |
PF03133(TTL) | 4 | VAL A 288TRP A 292PHE A 277GLU A 279 | None | 1.39A | 5agkA-4ylrA:undetectable5agkB-4ylrA:undetectable | 5agkA-4ylrA:22.815agkB-4ylrA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ypl | LON PROTEASE (Meiothermustaiwanensis) |
PF00004(AAA)PF05362(Lon_C) | 4 | MET A 713ARG A 709VAL A 762GLU A 705 | None | 1.31A | 5agkA-4yplA:undetectable5agkB-4yplA:undetectable | 5agkA-4yplA:21.245agkB-4yplA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zva | DIGUANYLATE CYCLASEDOSC (Escherichiacoli) |
PF11563(Protoglobin) | 4 | MET A 8VAL A 84TRP A 12GLU A 11 | None | 1.30A | 5agkA-4zvaA:undetectable5agkB-4zvaA:2.1 | 5agkA-4zvaA:18.865agkB-4zvaA:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5by3 | BTGH115A (Bacteroidesthetaiotaomicron) |
PF15979(Glyco_hydro_115) | 4 | ARG A 505VAL A 736TRP A 732GLU A 731 | None | 1.37A | 5agkA-5by3A:undetectable5agkB-5by3A:undetectable | 5agkA-5by3A:19.825agkB-5by3A:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c6g | AGR133CPSISTER CHROMATIDCOHESION PROTEIN 2 (Eremotheciumgossypii) |
PF10345(Cohesin_load)no annotation | 4 | VAL B 28TRP A 401PHE A 397GLU A 402 | None | 1.48A | 5agkA-5c6gB:undetectable5agkB-5c6gB:undetectable | 5agkA-5c6gB:18.695agkB-5c6gB:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fjn | L-AMINO ACIDDEAMINASE (Cosenzaeamyxofaciens) |
PF01266(DAO) | 4 | ARG A 316VAL A 438TRP A 439GLU A 418 | BE2 A1476 (-4.0A)BE2 A1476 ( 4.3A)BE2 A1476 ( 3.7A)None | 1.27A | 5agkA-5fjnA:undetectable5agkB-5fjnA:undetectable | 5agkA-5fjnA:23.275agkB-5fjnA:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kn8 | ADENINE DNAGLYCOSYLASE (Geobacillusstearothermophilus) |
PF00633(HHH)PF00730(HhH-GPD) | 4 | VAL A 92TRP A 83PHE A 61GLU A 84 | None | 1.35A | 5agkA-5kn8A:undetectable5agkB-5kn8A:undetectable | 5agkA-5kn8A:22.285agkB-5kn8A:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8t | 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACIDOXIDASE (Homo sapiens) |
PF00264(Tyrosinase) | 4 | ARG A 225TRP A 414PHE A 411GLU A 413 | None | 1.09A | 5agkA-5m8tA:undetectable5agkB-5m8tA:undetectable | 5agkA-5m8tA:20.005agkB-5m8tA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wq3 | CYTOKININ RIBOSIDE5'-MONOPHOSPHATEPHOSPHORIBOHYDROLASE (Corynebacteriumglutamicum) |
PF03641(Lysine_decarbox) | 4 | MET A 112ARG A 155VAL A 104PHE A 159 | None | 1.43A | 5agkA-5wq3A:undetectable5agkB-5wq3A:undetectable | 5agkA-5wq3A:24.235agkB-5wq3A:24.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x89 | ENDA-LIKEPROTEIN,TRNA-SPLICING ENDONUCLEASE (Methanopyruskandleri) |
no annotation | 4 | MET A 249VAL A 231PHE A 258GLU A 253 | None | 0.97A | 5agkA-5x89A:undetectable5agkB-5x89A:undetectable | 5agkA-5x89A:12.705agkB-5x89A:12.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xf7 | PROTEINDISULFIDE-ISOMERASE-LIKE PROTEIN OF THETESTIS (Homo sapiens) |
no annotation | 4 | ARG A 129VAL A 65PHE A 113GLU A 106 | None | 1.23A | 5agkA-5xf7A:undetectable5agkB-5xf7A:undetectable | 5agkA-5xf7A:10.855agkB-5xf7A:10.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwd | VH CHAIN OF 059-152VL CHAIN OF 059-152 (Homo sapiens) |
no annotation | 4 | MET H 105VAL D 98TRP D 91TRP H 49 | None | 1.18A | 5agkA-5xwdH:undetectable5agkB-5xwdH:undetectable | 5agkA-5xwdH:9.595agkB-5xwdH:9.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bk1 | UDP-GLYCOSYLTRANSFERASE 79 (Oryza sativa) |
no annotation | 4 | ARG A 331VAL A 317TRP A 316GLU A 322 | NoneUDP A 501 ( 4.8A)NoneNone | 1.28A | 5agkA-6bk1A:undetectable5agkB-6bk1A:undetectable | 5agkA-6bk1A:13.485agkB-6bk1A:13.48 |