SIMILAR PATTERNS OF AMINO ACIDS FOR 5A7M_A_ACTA1923_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cu1 PROTEIN
(PROTEASE/HELICASE
NS3)

(Hepacivirus C) 		PF02907
(Peptidase_S29)
PF07652
(Flavi_DEAD) 		3 ASP A 285
ARG A 316
TYR A 223
 None
 0.73A 5a7mA-1cu1A:
undetectable		 5a7mA-1cu1A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k0g P-AMINOBENZOATE
SYNTHASE COMPONENT I

(Escherichia
coli) 		PF00425
(Chorismate_bind)
PF04715
(Anth_synt_I_N) 		3 ASP A 208
ARG A 374
TYR A 203
 None
 1.05A 5a7mA-1k0gA:
undetectable		 5a7mA-1k0gA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1llc L-LACTATE
DEHYDROGENASE

(Lactobacillus
casei) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		3 ASP A 234
ARG A 233
TYR A 237
 None
 0.82A 5a7mA-1llcA:
undetectable		 5a7mA-1llcA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m5y SURVIVAL PROTEIN
SURA

(Escherichia
coli) 		PF00639
(Rotamase)
PF09312
(SurA_N)
PF13616
(Rotamase_3) 		3 ASP A 121
ARG A 117
TYR A 120
 None
 1.03A 5a7mA-1m5yA:
undetectable		 5a7mA-1m5yA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nd4 AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E

(Klebsiella
pneumoniae) 		PF01636
(APH) 		3 ASP A 216
ARG A 217
TYR A 218
 None
 1.02A 5a7mA-1nd4A:
undetectable		 5a7mA-1nd4A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1odu PUTATIVE
ALPHA-L-FUCOSIDASE

(Thermotoga
maritima) 		PF01120
(Alpha_L_fucos) 		3 ASP A 190
ARG A 186
TYR A 187
 None
 1.05A 5a7mA-1oduA:
4.3		 5a7mA-1oduA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1orq POTASSIUM CHANNEL

(Aeropyrum
pernix) 		PF00520
(Ion_trans) 		3 ASP C  72
ARG C  76
TYR C  73
 None
 0.97A 5a7mA-1orqC:
undetectable		 5a7mA-1orqC:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qk1 CREATINE KINASE,
UBIQUITOUS
MITOCHONDRIAL

(Homo sapiens) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		3 ASP A 357
ARG A 361
TYR A 354
 None
 0.93A 5a7mA-1qk1A:
undetectable		 5a7mA-1qk1A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rv9 CONSERVED
HYPOTHETICAL PROTEIN
NMB0706

(Neisseria
meningitidis) 		PF02578
(Cu-oxidase_4) 		3 ASP A 117
ARG A 240
TYR A 239
 None
 0.93A 5a7mA-1rv9A:
2.3		 5a7mA-1rv9A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xzz INOSITOL
1,4,5-TRISPHOSPHATE
RECEPTOR TYPE 1

(Mus musculus) 		PF08709
(Ins145_P3_rec) 		3 ASP A 174
ARG A 170
TYR A 117
 None
GOL  A1001 (-4.8A)
None
 0.98A 5a7mA-1xzzA:
undetectable		 5a7mA-1xzzA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y6z HEAT SHOCK PROTEIN,
PUTATIVE

(Plasmodium
falciparum) 		PF00183
(HSP90) 		3 ASP A 100
ARG A  77
TYR A  74
 None
 1.00A 5a7mA-1y6zA:
undetectable		 5a7mA-1y6zA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aaf ARGININE DEIMINASE

(Pseudomonas
aeruginosa) 		PF02274
(Amidinotransf) 		3 ASP A 373
ARG A 374
TYR A 372
 None
 1.04A 5a7mA-2aafA:
undetectable		 5a7mA-2aafA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bde CYTOSOLIC IMP-GMP
SPECIFIC
5'-NUCLEOTIDASE

(Legionella
pneumophila) 		PF05761
(5_nucleotid) 		3 ASP A 253
ARG A 249
TYR A 252
 None
 1.00A 5a7mA-2bdeA:
3.0		 5a7mA-2bdeA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bpa PROTEIN (SUBUNIT OF
BACTERIOPHAGE
PHIX174)

(Escherichia
virus phiX174) 		PF02305
(Phage_F) 		3 ASP 1 104
ARG 1 157
TYR 1 102
 None
 0.97A 5a7mA-2bpa1:
undetectable		 5a7mA-2bpa1:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2csg PUTATIVE CYTOPLASMIC
PROTEIN

(Salmonella
enterica) 		PF07350
(DUF1479) 		3 ASP A 186
ARG A 187
TYR A 361
 ICT  A 501 (-2.6A)
ICT  A 501 (-3.6A)
SIN  A 502 (-4.2A)
 0.58A 5a7mA-2csgA:
undetectable		 5a7mA-2csgA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2czo BUD EMERGENCE
PROTEIN 1

(Saccharomyces
cerevisiae) 		PF00787
(PX) 		3 ASP A 320
ARG A 316
TYR A 317
 None
 0.83A 5a7mA-2czoA:
undetectable		 5a7mA-2czoA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dbn HYPOTHETICAL PROTEIN
YBIU

(Escherichia
coli) 		PF07350
(DUF1479) 		3 ASP A 186
ARG A 187
TYR A 361
 None
None
SO4  A 703 ( 4.2A)
 0.76A 5a7mA-2dbnA:
undetectable		 5a7mA-2dbnA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dgx KIAA0430 PROTEIN

(Homo sapiens) 		PF00076
(RRM_1) 		3 ASP A 563
ARG A 565
TYR A 564
 None
 0.98A 5a7mA-2dgxA:
undetectable		 5a7mA-2dgxA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ejw HOMOSERINE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00742
(Homoserine_dh)
PF03447
(NAD_binding_3) 		3 ASP A 301
ARG A 304
TYR A 119
 None
 0.99A 5a7mA-2ejwA:
undetectable		 5a7mA-2ejwA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ezl TRANSPOSASE

(Escherichia
virus Mu) 		PF02316
(HTH_Tnp_Mu_1) 		3 ASP A 147
ARG A 146
TYR A 150
 None
 1.05A 5a7mA-2ezlA:
undetectable		 5a7mA-2ezlA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iag PROSTACYCLIN
SYNTHASE

(Homo sapiens) 		PF00067
(p450) 		3 ASP A 381
ARG A 378
TYR A  73
 None
 0.94A 5a7mA-2iagA:
undetectable		 5a7mA-2iagA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2klx GLUTAREDOXIN

(Bartonella
henselae) 		PF00462
(Glutaredoxin) 		3 ASP A  66
ARG A  17
TYR A  69
 None
 0.88A 5a7mA-2klxA:
undetectable		 5a7mA-2klxA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l9v PRE-MRNA-PROCESSING
FACTOR 40 HOMOLOG A

(Homo sapiens) 		PF01846
(FF) 		3 ASP A  46
ARG A  48
TYR A  49
 None
 1.01A 5a7mA-2l9vA:
undetectable		 5a7mA-2l9vA:
7.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o8r POLYPHOSPHATE KINASE

(Porphyromonas
gingivalis) 		PF02503
(PP_kinase)
PF13089
(PP_kinase_N)
PF13090
(PP_kinase_C) 		3 ASP A 270
ARG A 272
TYR A 228
 None
 0.95A 5a7mA-2o8rA:
undetectable		 5a7mA-2o8rA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qr4 PEPTIDASE M3B,
OLIGOENDOPEPTIDASE F

(Enterococcus
faecium) 		PF01432
(Peptidase_M3)
PF08439
(Peptidase_M3_N) 		3 ASP A  31
ARG A  98
TYR A  34
 None
 1.04A 5a7mA-2qr4A:
undetectable		 5a7mA-2qr4A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x8r GLYCOSYL HYDROLASE

(Aspergillus
fumigatus) 		PF01183
(Glyco_hydro_25) 		3 ASP A  75
ARG A  73
TYR A 116
 None
 0.90A 5a7mA-2x8rA:
3.9		 5a7mA-2x8rA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xty QNRB1

(Klebsiella
pneumoniae) 		PF00805
(Pentapeptide)
PF13599
(Pentapeptide_4) 		3 ASP A  70
ARG A  90
TYR A  46
 None
 0.84A 5a7mA-2xtyA:
undetectable		 5a7mA-2xtyA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xz3 MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
ENVELOPE
GLYCOPROTEIN

(Escherichia
coli;
Bovine leukemia
virus) 		PF00429
(TLV_coat)
PF13416
(SBP_bac_8) 		3 ASP A 442
ARG A 438
TYR A 445
 None
EDO  A1493 (-3.8A)
None
 0.94A 5a7mA-2xz3A:
undetectable		 5a7mA-2xz3A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN

(Chromobacterium
violaceum) 		PF03536
(VRP3) 		3 ASP A 201
ARG A 213
TYR A 212
 None
SO4  A   1 (-3.8A)
None
 0.85A 5a7mA-3bo6A:
undetectable		 5a7mA-3bo6A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6k PUTATIVE
AMINOTRANSFERASE

(Corynebacterium
diphtheriae) 		PF12897
(Aminotran_MocR) 		3 ASP A 139
ARG A 140
TYR A 138
 None
None
EDO  A 422 (-3.9A)
 1.02A 5a7mA-3d6kA:
4.2		 5a7mA-3d6kA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fmx TARTRATE
DEHYDROGENASE/DECARB
OXYLASE

(Pseudomonas
putida) 		PF00180
(Iso_dh) 		3 ASP X 317
ARG X 319
TYR X 320
 None
 0.91A 5a7mA-3fmxX:
2.4		 5a7mA-3fmxX:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwf CYCLOHEXANONE
MONOOXYGENASE

(Rhodococcus sp.
HI-31) 		PF00743
(FMO-like) 		3 ASP A  95
ARG A  99
TYR A  92
 None
 0.91A 5a7mA-3gwfA:
undetectable		 5a7mA-3gwfA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhs PHENOLOXIDASE
SUBUNIT 1

(Manduca sexta) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		3 ASP B 647
ARG B 648
TYR B 644
 None
 0.80A 5a7mA-3hhsB:
undetectable		 5a7mA-3hhsB:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5g MYOSIN HEAVY CHAIN
ISOFORM A

(Doryteuthis
pealeii) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF02736
(Myosin_N) 		3 ASP A 157
ARG A 141
TYR A 160
 None
 1.03A 5a7mA-3i5gA:
undetectable		 5a7mA-3i5gA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9v NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 3

(Thermus
thermophilus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4)
PF10588
(NADH-G_4Fe-4S_3)
PF13510
(Fer2_4) 		3 ASP 3 752
ARG 3 455
TYR 3 454
 None
 0.82A 5a7mA-3i9v3:
3.7		 5a7mA-3i9v3:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jbb ALLOPHYCOCYANIN BETA
CHAIN

(Halomicronema
hongdechloris) 		PF00502
(Phycobilisome) 		3 ASP B  84
ARG B  83
TYR B  87
 CYC  B 201 (-2.7A)
None
CYC  B 201 (-4.2A)
 1.03A 5a7mA-3jbbB:
undetectable		 5a7mA-3jbbB:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3khj INOSINE-5-MONOPHOSPH
ATE DEHYDROGENASE

(Cryptosporidium
parvum) 		PF00478
(IMPDH) 		3 ASP A 260
ARG A 256
TYR A 257
 None
 0.98A 5a7mA-3khjA:
5.9		 5a7mA-3khjA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ml0 PENICILLIN G
ACYLASE, ALPHA
SUBUNIT

(Alcaligenes
faecalis) 		PF01804
(Penicil_amidase) 		3 ASP A  93
ARG A  96
TYR A  23
 None
 0.87A 5a7mA-3ml0A:
undetectable		 5a7mA-3ml0A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mpi GLUTARYL-COA
DEHYDROGENASE

(Desulfococcus
multivorans) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		3 ASP A 233
ARG A 236
TYR A 104
 None
GRA  A 402 ( 4.1A)
None
 1.04A 5a7mA-3mpiA:
undetectable		 5a7mA-3mpiA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n9x PHOSPHOTRANSFERASE

(Plasmodium
berghei) 		PF00069
(Pkinase) 		3 ASP A  68
ARG A  71
TYR A  39
 None
 1.05A 5a7mA-3n9xA:
undetectable		 5a7mA-3n9xA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3npf PUTATIVE
DIPEPTIDYL-PEPTIDASE
VI

(Bacteroides
ovatus) 		PF00877
(NLPC_P60) 		3 ASP A  78
ARG A 220
TYR A  80
 None
GOL  A 329 (-3.5A)
GOL  A 329 (-4.7A)
 1.06A 5a7mA-3npfA:
undetectable		 5a7mA-3npfA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ol2 PLEXIN-B1

(Homo sapiens) 		PF01403
(Sema)
PF01437
(PSI) 		3 ASP B 496
ARG B 430
TYR B 498
 None
 0.86A 5a7mA-3ol2B:
undetectable		 5a7mA-3ol2B:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pig BETA-FRUCTOFURANOSID
ASE

(Bifidobacterium
longum) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		3 ASP A 432
ARG A 404
TYR A 443
 None
 1.03A 5a7mA-3pigA:
undetectable		 5a7mA-3pigA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppl ASPARTATE
AMINOTRANSFERASE

(Corynebacterium
glutamicum) 		PF12897
(Aminotran_MocR) 		3 ASP A 143
ARG A 144
TYR A 142
 UNL  A 600 ( 2.8A)
UNL  A 600 ( 3.5A)
PLP  A 500 (-3.8A)
 1.05A 5a7mA-3pplA:
4.8		 5a7mA-3pplA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u9i MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME,
C-TERMINAL DOMAIN
PROTEIN

(Roseiflexus sp.
RS-1) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASP A 114
ARG A 118
TYR A  51
 None
 0.75A 5a7mA-3u9iA:
3.7		 5a7mA-3u9iA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v8d CHOLESTEROL
7-ALPHA-MONOOXYGENAS
E

(Homo sapiens) 		PF00067
(p450) 		3 ASP A 385
ARG A 382
TYR A  75
 None
 1.02A 5a7mA-3v8dA:
undetectable		 5a7mA-3v8dA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vil BETA-GLUCOSIDASE

(Neotermes
koshunensis) 		PF00232
(Glyco_hydro_1) 		3 ASP A 218
ARG A 353
TYR A 219
 None
 0.93A 5a7mA-3vilA:
4.7		 5a7mA-3vilA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w0k BIFUNCTIONAL
ENDOMANNANASE/ENDOGL
UCANASE

(Caldanaerobius
polysaccharolyticus) 		PF00150
(Cellulase) 		3 ASP A  44
ARG A  85
TYR A  45
 None
 1.01A 5a7mA-3w0kA:
4.2		 5a7mA-3w0kA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w5f BETA-GALACTOSIDASE

(Solanum
lycopersicum) 		PF01301
(Glyco_hydro_35) 		3 ASP A 378
ARG A 380
TYR A 381
 None
 1.03A 5a7mA-3w5fA:
3.4		 5a7mA-3w5fA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wel ALPHA-GLUCOSIDASE

(Beta vulgaris) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16863
(NtCtMGAM_N) 		3 ASP A 575
ARG A 572
TYR A 578
 None
 0.98A 5a7mA-3welA:
2.5		 5a7mA-3welA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C

(Lethenteron
camtschaticum) 		PF01462
(LRRNT)
PF13855
(LRR_8) 		3 ASP A  74
ARG A 120
TYR A  99
 None
 0.99A 5a7mA-3wo9A:
undetectable		 5a7mA-3wo9A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aef NEOPULLULANASE
(ALPHA-AMYLASE II)

(Pyrococcus
furiosus) 		PF00128
(Alpha-amylase)
PF02903
(Alpha-amylase_N)
PF16561
(AMPK1_CBM) 		3 ASP A 460
ARG A 457
TYR A  91
 None
 0.98A 5a7mA-4aefA:
4.6		 5a7mA-4aefA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ays AMYLOSUCRASE

(Deinococcus
radiodurans) 		PF00128
(Alpha-amylase) 		3 ASP A  95
ARG A  96
TYR A  93
 None
 1.01A 5a7mA-4aysA:
3.2		 5a7mA-4aysA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cbx ACTIN-2

(Plasmodium
berghei) 		PF00022
(Actin) 		3 ASP A 184
ARG A 183
TYR A 187
 None
 0.98A 5a7mA-4cbxA:
undetectable		 5a7mA-4cbxA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ev4 CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1

(Serratia
fonticola) 		PF13354
(Beta-lactamase2) 		3 ASP A  98
ARG A  96
TYR A  97
 None
 0.99A 5a7mA-4ev4A:
undetectable		 5a7mA-4ev4A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gcr GAMMA-B CRYSTALLIN

(Bos taurus) 		PF00030
(Crystall) 		3 ASP A  64
ARG A   9
TYR A  65
 None
 1.02A 5a7mA-4gcrA:
undetectable		 5a7mA-4gcrA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB

(Acinetobacter
baumannii) 		PF01636
(APH) 		3 ASP A 224
ARG A 225
TYR A 226
 None
 1.03A 5a7mA-4gkhA:
undetectable		 5a7mA-4gkhA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gxt A CONSERVED
FUNCTIONALLY UNKNOWN
PROTEIN

(Anaerococcus
prevotii) 		PF12710
(HAD) 		3 ASP A 246
ARG A 249
TYR A 177
 None
 0.99A 5a7mA-4gxtA:
3.4		 5a7mA-4gxtA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iyp IMMUNOGLOBULIN-BINDI
NG PROTEIN 1
SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
CATALYTIC SUBUNIT
ALPHA ISOFORM

(Homo sapiens;
Homo sapiens) 		PF04177
(TAP42)
PF00149
(Metallophos) 		3 ASP C 131
ARG A 221
TYR C 130
 None
 0.96A 5a7mA-4iypC:
undetectable		 5a7mA-4iypC:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kem MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Azospirillum
lipoferum) 		PF13378
(MR_MLE_C) 		3 ASP A 257
ARG A 258
TYR A 256
 None
 1.02A 5a7mA-4kemA:
3.3		 5a7mA-4kemA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lec PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21A

(Homo sapiens) 		PF10294
(Methyltransf_16) 		3 ASP A 180
ARG A 176
TYR A 177
 None
 0.92A 5a7mA-4lecA:
2.3		 5a7mA-4lecA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m29 BETA-XYLOSIDASE

(Caulobacter
vibrioides) 		PF01229
(Glyco_hydro_39) 		3 ASP A 438
ARG A 435
TYR A 295
 None
 0.79A 5a7mA-4m29A:
5.1		 5a7mA-4m29A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mt4 CMEC

(Campylobacter
jejuni) 		PF02321
(OEP) 		3 ASP A 132
ARG A 131
TYR A 287
 None
 0.93A 5a7mA-4mt4A:
undetectable		 5a7mA-4mt4A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nzs BETA-KETOTHIOLASE
BKTB

(Cupriavidus
necator) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		3 ASP A 313
ARG A 373
TYR A 374
 None
 0.58A 5a7mA-4nzsA:
undetectable		 5a7mA-4nzsA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q65 DIPEPTIDE PERMEASE D

(Escherichia
coli) 		PF00854
(PTR2) 		3 ASP A 133
ARG A 135
TYR A 129
 None
 0.89A 5a7mA-4q65A:
undetectable		 5a7mA-4q65A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgk UNCHARACTERIZED
PROTEIN

(Yersinia pestis) 		PF07350
(DUF1479) 		3 ASP A 183
ARG A 184
TYR A 356
 EDO  A 505 ( 4.3A)
None
None
 0.73A 5a7mA-4rgkA:
undetectable		 5a7mA-4rgkA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4sli INTRAMOLECULAR
TRANS-SIALIDASE

(Macrobdella
decora) 		PF02973
(Sialidase)
PF13088
(BNR_2) 		3 ASP A 732
ARG A 673
TYR A 731
 None
CNP  A 760 (-3.0A)
None
 0.96A 5a7mA-4sliA:
undetectable		 5a7mA-4sliA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4usq PYRIDINE
NUCLEOTIDE-DISULFIDE
OXIDOREDUCTASE

(Cellvibrio sp.
BR) 		PF13738
(Pyr_redox_3) 		3 ASP A  15
ARG A 131
TYR A  37
 None
 0.66A 5a7mA-4usqA:
2.5		 5a7mA-4usqA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wph UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7

(Homo sapiens) 		PF12436
(USP7_ICP0_bdg) 		3 ASP A 789
ARG A 793
TYR A 786
 None
 0.81A 5a7mA-4wphA:
undetectable		 5a7mA-4wphA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x6k ANHYDROSIALIDASE

([Ruminococcus]
gnavus) 		PF13088
(BNR_2) 		3 ASP A 696
ARG A 637
TYR A 695
 None
3XR  A 802 (-3.0A)
None
 0.98A 5a7mA-4x6kA:
undetectable		 5a7mA-4x6kA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9e DEOXYGUANOSINETRIPHO
SPHATE
TRIPHOSPHOHYDROLASE

(Escherichia
coli) 		PF01966
(HD) 		3 ASP A 495
ARG A 499
TYR A 492
 None
 0.96A 5a7mA-4x9eA:
undetectable		 5a7mA-4x9eA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhb SIALIDASE B

(Streptococcus
pneumoniae) 		PF02012
(BNR)
PF02973
(Sialidase)
PF13088
(BNR_2) 		3 ASP A 672
ARG A 619
TYR A 671
 None
NHE  A 702 (-2.9A)
None
 1.00A 5a7mA-4xhbA:
undetectable		 5a7mA-4xhbA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhc ALPHA-L-RHAMNOSIDASE

(Klebsiella
oxytoca) 		PF17389
(Bac_rhamnosid6H) 		3 ASP A 290
ARG A 361
TYR A 293
 None
 0.92A 5a7mA-4xhcA:
undetectable		 5a7mA-4xhcA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yeq LAMININ SUBUNIT
ALPHA-2

(Homo sapiens) 		PF00052
(Laminin_B) 		3 ASP U 141
ARG U 147
TYR U 138
 None
 0.71A 5a7mA-4yeqU:
undetectable		 5a7mA-4yeqU:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zaa FDC1

(Aspergillus
niger) 		PF01977
(UbiD) 		3 ASP A 407
ARG A 363
TYR A 409
 None
 0.91A 5a7mA-4zaaA:
undetectable		 5a7mA-4zaaA:
21.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5a7m BETA-XYLOSIDASE

(Trichoderma
reesei) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 ASP A  95
ARG A  96
TYR A 429
 ZN  A1903 ( 2.1A)
ACT  A1923 (-4.1A)
ACT  A1923 ( 4.2A)
 0.01A 5a7mA-5a7mA:
74.7		 5a7mA-5a7mA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c6u AMINOTRANSFERASE

(Mycobacterium
tuberculosis) 		PF12897
(Aminotran_MocR) 		3 ASP A 140
ARG A 141
TYR A 139
 None
None
PLP  A 501 ( 3.6A)
 1.04A 5a7mA-5c6uA:
undetectable		 5a7mA-5c6uA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d9a POLYMERASE ACIDIC
PROTEIN

(Influenza C
virus) 		PF00603
(Flu_PA) 		3 ASP A 482
ARG A 464
TYR A 462
 None
 0.79A 5a7mA-5d9aA:
undetectable		 5a7mA-5d9aA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eb0 YFIB

(Pseudomonas
aeruginosa) 		PF00691
(OmpA) 		3 ASP A 102
ARG A 155
TYR A 104
 None
 1.03A 5a7mA-5eb0A:
undetectable		 5a7mA-5eb0A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5epo 7-ALPHA-HYDROXYSTERO
ID DEYDROGENASE

(Clostridium
sardiniense) 		PF13561
(adh_short_C2) 		3 ASP A  99
ARG A 155
TYR A 158
 None
TUD  A 302 (-4.2A)
TUD  A 302 ( 4.5A)
 1.02A 5a7mA-5epoA:
5.5		 5a7mA-5epoA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo sapiens) 		PF03071
(GNT-I)
PF15711
(ILEI) 		3 ASP A 179
ARG A 207
TYR A 152
 None
 0.90A 5a7mA-5gggA:
undetectable		 5a7mA-5gggA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ggk PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo sapiens) 		PF15711
(ILEI) 		3 ASP A 179
ARG A 207
TYR A 152
 MBE  A 301 ( 3.0A)
MBE  A 301 (-3.9A)
MBE  A 301 (-4.2A)
 0.95A 5a7mA-5ggkA:
undetectable		 5a7mA-5ggkA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hmm EXODEOXYRIBONUCLEASE

(Escherichia
virus T5) 		PF01367
(5_3_exonuc)
PF02739
(5_3_exonuc_N) 		3 ASP A 187
ARG A 222
TYR A 181
 None
 0.91A 5a7mA-5hmmA:
undetectable		 5a7mA-5hmmA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jir OOP FAMILY OMPA-OMPF
PORIN

(Treponema
pallidum) 		no annotation 3 ASP B 129
ARG B 126
TYR B 336
 GOL  B 501 ( 4.1A)
None
None
 0.90A 5a7mA-5jirB:
undetectable		 5a7mA-5jirB:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxu DYP-TYPE PEROXIDASE
FAMILY

(Thermomonospora
curvata) 		PF04261
(Dyp_perox) 		3 ASP A 343
ARG A 257
TYR A 332
 None
 0.99A 5a7mA-5jxuA:
undetectable		 5a7mA-5jxuA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mg8 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
5

(Schizosaccharomyces
pombe) 		no annotation 3 ASP A 547
ARG A 533
TYR A 544
 None
 0.89A 5a7mA-5mg8A:
undetectable		 5a7mA-5mg8A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n8o DNA HELICASE I

(Escherichia
coli) 		PF07057
(TraI)
PF08751
(TrwC)
PF13604
(AAA_30) 		3 ASP A1468
ARG A1118
TYR A 926
 None
 0.99A 5a7mA-5n8oA:
undetectable		 5a7mA-5n8oA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oih -

(-) 		no annotation 3 ASP A 357
ARG A 354
TYR A 392
 None
 0.99A 5a7mA-5oihA:
undetectable		 5a7mA-5oihA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5thx FERREDOXIN--NADP
REDUCTASE

(Neisseria
gonorrhoeae) 		PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		3 ASP A 149
ARG A 145
TYR A 146
 NAP  A 301 (-3.2A)
NAP  A 301 (-3.5A)
NAP  A 301 (-4.2A)
 0.71A 5a7mA-5thxA:
3.3		 5a7mA-5thxA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wdx JFH-1 NS3

(Hepacivirus C) 		no annotation 3 ASP A 285
ARG A 316
TYR A 223
 None
 1.00A 5a7mA-5wdxA:
undetectable		 5a7mA-5wdxA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xep CHITINASE-3-LIKE
PROTEIN 1

(Mus musculus) 		no annotation 3 ASP A 147
ARG A 146
TYR A 150
 None
 0.85A 5a7mA-5xepA:
5.8		 5a7mA-5xepA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y33 ALGINATE LYASE

(Flavobacterium
sp. UMI-01) 		no annotation 3 ASP A 151
ARG A 156
TYR A 149
 None
 0.96A 5a7mA-5y33A:
undetectable		 5a7mA-5y33A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yay KN MOTIF AND ANKYRIN
REPEAT DOMAINS 1

(Mus musculus) 		no annotation 3 ASP A1146
ARG A1090
TYR A1091
 None
 1.01A 5a7mA-5yayA:
undetectable		 5a7mA-5yayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yud BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 1E

(Mus musculus) 		no annotation 3 ASP A 193
ARG A 192
TYR A 172
 None
 0.95A 5a7mA-5yudA:
undetectable		 5a7mA-5yudA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ayi HTH-TYPE
TRANSCRIPTIONAL
REGULATOR UIDR

(Escherichia
coli) 		no annotation 3 ASP A 161
ARG A 157
TYR A 164
 None
None
C3G  A 201 (-4.7A)
 0.91A 5a7mA-6ayiA:
undetectable		 5a7mA-6ayiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c1d UNCONVENTIONAL
MYOSIN-IB

(Rattus
norvegicus) 		no annotation 3 ASP P  89
ARG P  73
TYR P  92
 None
 0.80A 5a7mA-6c1dP:
undetectable		 5a7mA-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cyf -

(-) 		no annotation 3 ASP A 183
ARG A 185
TYR A 179
 None
 0.84A 5a7mA-6cyfA:
undetectable		 5a7mA-6cyfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6czs -

(-) 		no annotation 3 ASP A 235
ARG A 111
TYR A 109
 SO4  A 407 (-2.8A)
SO4  A 408 ( 3.2A)
None
 1.00A 5a7mA-6czsA:
undetectable		 5a7mA-6czsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6en4 SPLICING FACTOR 3B
SUBUNIT 3
SPLICING FACTOR 3B
SUBUNIT 1

(Homo sapiens;
Homo sapiens) 		no annotation
no annotation 		3 ASP C1301
ARG A 918
TYR C1298
 None
 0.90A 5a7mA-6en4C:
2.1		 5a7mA-6en4C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fyv DUAL SPECIFICITY
PROTEIN KINASE CLK4

(Homo sapiens) 		no annotation 3 ASP A 312
ARG A 311
TYR A 305
 None
 0.99A 5a7mA-6fyvA:
undetectable		 5a7mA-6fyvA:
undetectable