SIMILAR PATTERNS OF AMINO ACIDS FOR 5A06_D_SORD1342_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6v | METHYL-COENZYME MREDUCTASE I ALPHASUBUNITMETHYL-COENZYME MREDUCTASE I BETASUBUNIT (Methanopyruskandleri;Methanopyruskandleri) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N)PF02241(MCR_beta)PF02783(MCR_beta_N) | 4 | ARG B 384ARG A 464ASP B 229TYR B 191 | None | 1.27A | 5a06D-1e6vB:undetectable | 5a06D-1e6vB:22.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1evj | GLUCOSE-FRUCTOSEOXIDOREDUCTASE (Zymomonasmobilis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 6 | LYS A 129ARG A 157ARG A 200ASP A 213TYR A 217TYR A 296 | NAD A 500 (-3.4A)NAD A 500 (-3.9A)NAD A 500 (-3.0A)NoneNoneNAD A 500 (-4.8A) | 0.27A | 5a06D-1evjA:48.3 | 5a06D-1evjA:49.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ezf | FARNESYL-DIPHOSPHATEFARNESYLTRANSFERASE (Homo sapiens) |
PF00494(SQS_PSY) | 4 | ARG A 218PHE A 230ARG A 228ASP A 84 | None | 1.49A | 5a06D-1ezfA:undetectable | 5a06D-1ezfA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ezv | UBIQUINOL-CYTOCHROMEC REDUCTASE COMPLEXCORE PROTEIN I (Saccharomycescerevisiae) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 4 | PHE A 290ARG A 334ASP A 312TYR A 287 | None | 1.33A | 5a06D-1ezvA:undetectable | 5a06D-1ezvA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f7u | ARGINYL-TRNASYNTHETASE (Saccharomycescerevisiae) |
PF00750(tRNA-synt_1d)PF03485(Arg_tRNA_synt_N)PF05746(DALR_1) | 4 | ARG A 358ARG A 270ASP A 191TYR A 188 | ARG A 800 ( 4.6A)NoneNoneARG A 800 (-4.0A) | 1.50A | 5a06D-1f7uA:2.8 | 5a06D-1f7uA:21.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1h6d | PRECURSOR FORM OFGLUCOSE-FRUCTOSEOXIDOREDUCTASE (Zymomonasmobilis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 6 | LYS A 181ARG A 209ARG A 252ASP A 265TYR A 269TYR A 348 | GOL A 600 ( 2.5A)NDP A 500 (-4.0A)NDP A 500 ( 2.8A)GOL A 600 (-2.9A)GOL A 600 ( 4.3A)NDP A 500 (-4.8A) | 0.38A | 5a06D-1h6dA:48.5 | 5a06D-1h6dA:44.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nnt | OVOTRANSFERRIN (Gallus gallus) |
PF00405(Transferrin) | 4 | PHE A 65ARG A 332TYR A 72TYR A 42 | None | 1.39A | 5a06D-1nntA:undetectable | 5a06D-1nntA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rcw | CT610 (Chlamydiatrachomatis) |
PF03070(TENA_THI-4) | 4 | LYS A 152PHE A 214TYR A 27TYR A 141 | None | 1.36A | 5a06D-1rcwA:undetectable | 5a06D-1rcwA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wzc | MANNOSYL-3-PHOSPHOGLYCERATE PHOSPHATASE (Pyrococcushorikoshii) |
PF08282(Hydrolase_3) | 4 | LYS A 42ARG A 170ASP A 10TYR A 50 | PO4 A 401 ( 4.9A)NonePO4 A 401 ( 4.6A)None | 1.45A | 5a06D-1wzcA:5.1 | 5a06D-1wzcA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y3n | ALGQ1 (Sphingomonassp. A1) |
PF01547(SBP_bac_1) | 4 | ARG A 20ARG A 255ASP A 269TYR A 379 | MAV A 495 (-4.1A)BEM A 494 ( 4.8A)NoneNone | 1.41A | 5a06D-1y3nA:undetectable | 5a06D-1y3nA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ydw | AX110P-LIKE PROTEIN (Arabidopsisthaliana) |
PF01408(GFO_IDH_MocA) | 5 | LYS A 102PHE A 162ARG A 174ASP A 187TYR A 191 | None | 1.13A | 5a06D-1ydwA:37.4 | 5a06D-1ydwA:24.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ydw | AX110P-LIKE PROTEIN (Arabidopsisthaliana) |
PF01408(GFO_IDH_MocA) | 4 | PHE A 243ARG A 174ASP A 187TYR A 191 | None | 1.40A | 5a06D-1ydwA:37.4 | 5a06D-1ydwA:24.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dc5 | GLUTATHIONES-TRANSFERASE, MU 7 (Mus musculus) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | ARG A 25PHE A 216ARG A 173TYR A 14 | None | 1.13A | 5a06D-2dc5A:undetectable | 5a06D-2dc5A:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e21 | TRNA(ILE)-LYSIDINESYNTHASE (Aquifexaeolicus) |
PF01171(ATP_bind_3) | 4 | ARG A 113PHE A 158ASP A 137TYR A 114 | ANP A 500 (-3.0A)NoneNoneNone | 1.43A | 5a06D-2e21A:undetectable | 5a06D-2e21A:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2glx | 1,5-ANHYDRO-D-FRUCTOSE REDUCTASE (Ensiferadhaerens) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | LYS A 94PHE A 232ARG A 163ASP A 176 | NDP A1500 ( 2.9A)NoneNDP A1500 (-3.0A)ACT A1502 ( 3.9A) | 1.22A | 5a06D-2glxA:39.0 | 5a06D-2glxA:29.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bga | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N)PF16353(DUF4981) | 4 | LYS A 635ARG A 892PHE A 737ASP A 735 | None | 1.15A | 5a06D-3bgaA:undetectable | 5a06D-3bgaA:16.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bol | 5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINEMETHYLTRANSFERASE (Thermotogamaritima) |
PF00809(Pterin_bind)PF02574(S-methyl_trans) | 4 | ARG A 402ARG A 166TYR A 125TYR A 430 | None | 1.44A | 5a06D-3bolA:2.0 | 5a06D-3bolA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cze | SUCROSE HYDROLASE (Xanthomonascitri) |
PF00128(Alpha-amylase) | 4 | ARG A 197ARG A 49ASP A 51TYR A 201 | None | 1.49A | 5a06D-3czeA:undetectable | 5a06D-3czeA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dec | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N)PF16353(DUF4981) | 4 | LYS A 611ARG A 868PHE A 713ASP A 711 | None | 1.16A | 5a06D-3decA:undetectable | 5a06D-3decA:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dzu | RETINOIC ACIDRECEPTOR RXR-ALPHAPEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens;Homo sapiens) |
PF00104(Hormone_recep)PF00105(zf-C4)PF00104(Hormone_recep)PF00105(zf-C4) | 4 | PHE A 159ARG A 202ASP D 337TYR A 169 | None | 1.25A | 5a06D-3dzuA:undetectable | 5a06D-3dzuA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f5f | MALTOSE-BINDINGPERIPLASMIC PROTEIN,HEPARAN SULFATE2-O-SULFOTRANSFERASE1 (Escherichiacoli;Gallus gallus) |
PF03567(Sulfotransfer_2)PF13416(SBP_bac_8) | 4 | LYS A1083ARG A1080ARG A1189ASP A1181 | A3P A 673 (-3.3A)NoneNoneNone | 1.46A | 5a06D-3f5fA:undetectable | 5a06D-3f5fA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g8y | SUSD/RAGB-ASSOCIATEDESTERASE-LIKEPROTEIN (Bacteroidesvulgatus) |
PF12715(Abhydrolase_7) | 4 | ARG A 287ARG A 340ASP A 341TYR A 387 | None | 1.45A | 5a06D-3g8yA:2.1 | 5a06D-3g8yA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qyj | ALR0039 PROTEIN (Nostoc sp. PCC7120) |
PF00561(Abhydrolase_1) | 4 | LYS A 79ARG A 105ASP A 210TYR A 136 | None | 1.43A | 5a06D-3qyjA:4.1 | 5a06D-3qyjA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2p | RETINOIC ACIDINDUCIBLE PROTEIN I (Anasplatyrhynchos) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | LYS A 738ARG A 463ASP A 461TYR A 625 | None | 1.47A | 5a06D-4a2pA:undetectable | 5a06D-4a2pA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2q | RETINOIC ACIDINDUCIBLE PROTEIN I (Anasplatyrhynchos) |
PF00270(DEAD)PF00271(Helicase_C)PF16739(CARD_2) | 4 | LYS A 738ARG A 463ASP A 461TYR A 625 | None | 1.35A | 5a06D-4a2qA:undetectable | 5a06D-4a2qA:17.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aip | FE-REGULATED PROTEINB (Neisseriameningitidis) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | ARG A 385ARG A 462ASP A 464TYR A 125 | None | 0.91A | 5a06D-4aipA:undetectable | 5a06D-4aipA:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aqq | L2 PROTEIN III(PENTON BASE) (HumanmastadenovirusB) |
PF01686(Adeno_Penton_B) | 4 | ARG A 460PHE A 224ASP A 220TYR A 242 | None | 1.46A | 5a06D-4aqqA:undetectable | 5a06D-4aqqA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bg2 | PATF (Prochlorondidemni) |
no annotation | 4 | ARG A 239ASP A 190TYR A 138TYR A 300 | None | 1.49A | 5a06D-4bg2A:undetectable | 5a06D-4bg2A:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bzx | BIFUNCTIONAL ENZYMECYSN/CYSC (Mycobacteriumtuberculosis) |
PF01583(APS_kinase) | 4 | ARG A 530ARG A 592ASP A 550TYR A 583 | CIT A1623 (-3.9A)NoneEDO A1615 ( 4.0A)EDO A1615 ( 4.9A) | 1.29A | 5a06D-4bzxA:2.2 | 5a06D-4bzxA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gk8 | HISTIDINOL-PHOSPHATASE (Lactococcuslactis) |
PF02811(PHP) | 4 | ARG A 160PHE A 52ASP A 17TYR A 157 | GK8 A 305 (-3.0A)None ZN A 302 ( 2.2A)GK8 A 305 (-4.6A) | 1.40A | 5a06D-4gk8A:undetectable | 5a06D-4gk8A:21.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4h3v | OXIDOREDUCTASEDOMAIN PROTEIN (Kribbellaflavida) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | LYS A 103ARG A 178ASP A 191TYR A 335 | None | 1.15A | 5a06D-4h3vA:36.7 | 5a06D-4h3vA:30.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mqt | MUSCARINICACETYLCHOLINERECEPTOR M2 (Homo sapiens) |
PF00001(7tm_1) | 4 | ARG A 121PHE A 396TYR A 206TYR A 440 | None | 1.27A | 5a06D-4mqtA:undetectable | 5a06D-4mqtA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zd6 | HALOHYDRIN EPOXIDASEB (Corynebacteriumsp.) |
PF13561(adh_short_C2) | 4 | ARG A 135PHE A 170TYR A 19TYR A 131 | None CL A 301 (-4.8A)NoneNone | 1.41A | 5a06D-4zd6A:6.4 | 5a06D-4zd6A:23.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5a05 | ALDOSE-ALDOSEOXIDOREDUCTASE (Caulobactervibrioides) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 7 | LYS A 104ARG A 132PHE A 163ARG A 172ASP A 185TYR A 189TYR A 267 | BGC A1343 (-2.6A)NDP A1340 (-3.7A)GLC A1341 ( 3.6A)NDP A1340 (-2.8A)BGC A1343 ( 3.1A)BGC A1343 (-4.2A)BGC A1343 (-4.4A) | 0.11A | 5a06D-5a05A:57.5 | 5a06D-5a05A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a0d | SURFACE ANCHOREDPROTEIN (Clostridiumperfringens) |
PF08341(TED) | 4 | LYS A 111ARG A 212TYR A 123TYR A 193 | None | 1.34A | 5a06D-5a0dA:undetectable | 5a06D-5a0dA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8r | METHYL-COENZYME MREDUCTASE II SUBUNITALPHAMETHYL-COENZYME MREDUCTASE II SUBUNITGAMMA (Methanothermobactermarburgensis;Methanothermobactermarburgensis) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N)PF02241(MCR_beta)PF02783(MCR_beta_N) | 4 | ARG B 383ARG A 463ASP B 228TYR B 190 | None | 1.25A | 5a06D-5a8rB:undetectable | 5a06D-5a8rB:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eno | MULTIDRUG EFFLUXPUMP SUBUNITACRB,MULTIDRUGEFFLUX PUMP SUBUNITACRB (Escherichiacoli) |
PF00873(ACR_tran) | 4 | ARG A 185ARG A 620ASP A 276TYR A 772 | None | 1.11A | 5a06D-5enoA:undetectable | 5a06D-5enoA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f15 | 4-AMINO-4-DEOXY-L-ARABINOSE (L-ARA4N)TRANSFERASE (Cupriavidusmetallidurans) |
PF13231(PMT_2) | 4 | LYS A 203ARG A 270ASP A 158TYR A 345 | 5TR A 681 (-4.0A)5TR A 681 (-3.5A)None5TR A 681 (-4.5A) | 1.47A | 5a06D-5f15A:2.3 | 5a06D-5f15A:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h71 | ALGQ2 (Sphingomonassp.) |
PF01547(SBP_bac_1) | 4 | ARG A 20ARG A 255ASP A 269TYR A 379 | BEM A 502 ( 4.2A)MAW A 501 ( 4.8A)NoneNone | 1.39A | 5a06D-5h71A:undetectable | 5a06D-5h71A:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hqb | ALPHA-GLUCOSIDASE (Pseudoalteromonassp. K8) |
PF10566(Glyco_hydro_97)PF14508(GH97_N)PF14509(GH97_C) | 4 | ARG A 464ARG A 594ASP A 572TYR A 543 | None | 1.09A | 5a06D-5hqbA:2.3 | 5a06D-5hqbA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ht6 | HISTONE-LYSINEN-METHYLTRANSFERASE2E (Homo sapiens) |
PF00856(SET) | 4 | ARG A 106ARG A 95ASP A 93TYR A 55 | None | 1.41A | 5a06D-5ht6A:undetectable | 5a06D-5ht6A:14.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2h | O-METHYLTRANSFERASEFAMILY 2 (Planctopiruslimnophila) |
PF00891(Methyltransf_2)PF16864(Dimerisation2) | 4 | ARG A 274PHE A 319ASP A 126TYR A 327 | None | 1.30A | 5a06D-5i2hA:5.2 | 5a06D-5i2hA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iv8 | LPS BIOSYNTHESISPROTEIN (Klebsiellapneumoniae) |
PF04453(OstA_C) | 4 | ARG A 381PHE A 342ARG A 266ASP A 294 | None | 1.13A | 5a06D-5iv8A:undetectable | 5a06D-5iv8A:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iv9 | LPS-ASSEMBLY PROTEINLPTD (Klebsiellapneumoniae) |
PF03968(OstA)PF04453(OstA_C) | 4 | ARG A 358PHE A 319ARG A 243ASP A 271 | None | 1.32A | 5a06D-5iv9A:undetectable | 5a06D-5iv9A:16.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n28 | METHYL-COENZYME MREDUCTASE SUBUNITALPHAMETHYL-COENZYME MREDUCTASE, BETASUBUNIT (Methanotorrisformicicus;Methanotorrisformicicus) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N)PF02241(MCR_beta)PF02783(MCR_beta_N) | 4 | ARG B 384ARG A 463ASP B 228TYR B 190 | None | 1.23A | 5a06D-5n28B:undetectable | 5a06D-5n28B:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t3e | BACILLAMIDESYNTHETASEHETEROCYCLIZATIONDOMAIN (Thermoactinomycesvulgaris) |
PF00668(Condensation) | 4 | ARG A1168PHE A1014ASP A1133TYR A1121 | None | 1.27A | 5a06D-5t3eA:undetectable | 5a06D-5t3eA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uj1 | DNA TOPOISOMERASE 1 (Mycobacteriumtuberculosis) |
no annotation | 4 | ARG A 201ARG A 206ASP A 209TYR A 580 | None | 1.34A | 5a06D-5uj1A:2.3 | 5a06D-5uj1A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x55 | PROBABLE URACIL-DNAGLYCOSYLASE (Acanthamoebapolyphagamimivirus) |
PF03167(UDG) | 4 | ARG A 305ASP A 281TYR A 140TYR A 146 | None | 1.28A | 5a06D-5x55A:undetectable | 5a06D-5x55A:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y6q | ALDEHYDE OXIDASEMEDIUM SUBUNITALDEHYDE OXIDASELARGE SUBUNIT (Methylobacillussp. KY4400;Methylobacillussp. KY4400) |
no annotationno annotation | 4 | ARG C 445PHE B 292ARG B 321ASP C 648 | None | 1.44A | 5a06D-5y6qC:undetectable | 5a06D-5y6qC:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fk6 | RHODOPSIN (Bos taurus) |
no annotation | 4 | ARG A 135PHE A 261TYR A 223TYR A 306 | NoneBOG A 407 (-4.6A)NoneNone | 1.46A | 5a06D-6fk6A:undetectable | 5a06D-6fk6A:undetectable |