SIMILAR PATTERNS OF AMINO ACIDS FOR 4ZJZ_A_BEZA1001

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d4e FLAVOCYTOCHROME C
FUMARATE REDUCTASE


(Shewanella
oneidensis)
PF00890
(FAD_binding_2)
PF14537
(Cytochrom_c3_2)
4 ALA A 532
GLY A 557
ALA A 140
GLY A 137
None
0.69A 4zjzA-1d4eA:
undetectable
4zjzA-1d4eA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f8r L-AMINO ACID OXIDASE

(Calloselasma
rhodostoma)
PF01593
(Amino_oxidase)
4 ALA A 455
GLY A 473
ALA A  48
GLY A  45
None
0.70A 4zjzA-1f8rA:
undetectable
4zjzA-1f8rA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fl2 ALKYL HYDROPEROXIDE
REDUCTASE SUBUNIT F


(Escherichia
coli)
PF07992
(Pyr_redox_2)
4 ALA A 486
GLY A 504
ALA A 227
GLY A 224
None
0.68A 4zjzA-1fl2A:
undetectable
4zjzA-1fl2A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gz2 OVOCLEIDIN-17

(Gallus gallus)
PF00059
(Lectin_C)
5 ALA A  71
VAL A  75
PHE A  19
GLY A  70
ALA A  60
None
None
None
None
SEP  A  61 ( 3.7A)
1.35A 4zjzA-1gz2A:
undetectable
4zjzA-1gz2A:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3b ATP-DEPENDENT
PHOSPHOENOLPYRUVATE
CARBOXYKINASE


(Thermus
thermophilus)
PF01293
(PEPCK_ATP)
4 VAL A 212
PHE A 263
GLY A 107
ALA A 106
None
0.60A 4zjzA-1j3bA:
undetectable
4zjzA-1j3bA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m64 FLAVOCYTOCHROME C3

(Shewanella
frigidimarina)
PF00890
(FAD_binding_2)
PF14537
(Cytochrom_c3_2)
4 ALA A 532
GLY A 557
ALA A 141
GLY A 138
None
0.63A 4zjzA-1m64A:
undetectable
4zjzA-1m64A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mzj BETA-KETOACYLSYNTHAS
E III


(Streptomyces
sp. R1128)
PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III)
5 PRO A 335
VAL A 302
GLY A  18
ALA A  71
GLY A  16
None
1.04A 4zjzA-1mzjA:
undetectable
4zjzA-1mzjA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sez PROTOPORPHYRINOGEN
OXIDASE,
MITOCHONDRIAL


(Nicotiana
tabacum)
PF01593
(Amino_oxidase)
4 ALA A 466
GLY A 482
ALA A  28
GLY A  25
None
0.68A 4zjzA-1sezA:
undetectable
4zjzA-1sezA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tdf THIOREDOXIN
REDUCTASE


(Escherichia
coli)
PF07992
(Pyr_redox_2)
4 ALA A 284
GLY A 302
ALA A  20
GLY A  17
None
0.63A 4zjzA-1tdfA:
undetectable
4zjzA-1tdfA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tdk L-AMINO ACID OXIDASE

(Gloydius halys)
PF01593
(Amino_oxidase)
4 ALA A 455
GLY A 473
ALA A  48
GLY A  45
None
0.68A 4zjzA-1tdkA:
undetectable
4zjzA-1tdkA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6a L-LACTATE
DEHYDROGENASE A
CHAIN


(Cyprinus carpio)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
5 ALA A 256
VAL A 136
GLY A 253
ALA A  34
GLY A  32
None
1.24A 4zjzA-1v6aA:
2.0
4zjzA-1v6aA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrq SARCOSINE OXIDASE
ALPHA SUBUNIT


(Corynebacterium
sp. U-96)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF12831
(FAD_oxidored)
PF13510
(Fer2_4)
4 ALA A 415
GLY A 431
ALA A 142
GLY A 139
None
0.65A 4zjzA-1vrqA:
undetectable
4zjzA-1vrqA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wnb PUTATIVE BETAINE
ALDEHYDE
DEHYDROGENASE


(Escherichia
coli)
PF00171
(Aldedh)
4 ALA A  47
GLY A 195
ALA A 194
GLY A   9
None
0.67A 4zjzA-1wnbA:
1.5
4zjzA-1wnbA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wom SIGMA FACTOR SIGB
REGULATION PROTEIN
RSBQ


(Bacillus
subtilis)
PF12697
(Abhydrolase_6)
4 ALA A  24
VAL A  78
PHE A  92
GLY A  94
None
0.55A 4zjzA-1womA:
3.9
4zjzA-1womA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xdi RV3303C-LPDA

(Mycobacterium
tuberculosis)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 GLY A  14
ALA A  13
GLY A 332
MET A 336
None
FAD  A 999 (-3.5A)
None
None
0.65A 4zjzA-1xdiA:
undetectable
4zjzA-1xdiA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y56 HYPOTHETICAL PROTEIN
PH1363


(Pyrococcus
horikoshii)
PF07992
(Pyr_redox_2)
PF13510
(Fer2_4)
4 ALA A 347
GLY A 363
ALA A 121
GLY A 118
None
0.62A 4zjzA-1y56A:
undetectable
4zjzA-1y56A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ytl ACETYL-COA
DECARBOXYLASE/SYNTHA
SE COMPLEX EPSILON
SUBUNIT 2


(Archaeoglobus
fulgidus)
PF02552
(CO_dh)
4 VAL A  54
PHE A  74
GLY A  43
MET A  46
None
0.69A 4zjzA-1ytlA:
3.3
4zjzA-1ytlA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yy5 FMS1 PROTEIN

(Saccharomyces
cerevisiae)
PF01593
(Amino_oxidase)
4 ALA A 477
GLY A 496
ALA A  23
GLY A  20
None
0.69A 4zjzA-1yy5A:
undetectable
4zjzA-1yy5A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a87 THIOREDOXIN
REDUCTASE


(Mycobacterium
tuberculosis)
PF07992
(Pyr_redox_2)
4 ALA A 286
GLY A 304
ALA A  29
GLY A  26
None
0.69A 4zjzA-2a87A:
undetectable
4zjzA-2a87A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE


(Pseudomonas sp.
SY-77-1)
PF01804
(Penicil_amidase)
5 PRO C 379
PHE C 355
GLY C 365
ALA C 364
GLY C 362
None
1.29A 4zjzA-2advC:
undetectable
4zjzA-2advC:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ag1 BENZALDEHYDE LYASE

(Pseudomonas
fluorescens)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
5 ALA A 431
VAL A 390
GLY A  59
ALA A  56
GLY A 426
None
0.93A 4zjzA-2ag1A:
3.1
4zjzA-2ag1A:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cdu NADPH OXIDASE

(Lactobacillus
sanfranciscensis)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 ALA A 280
GLY A 307
ALA A  15
GLY A  12
None
0.67A 4zjzA-2cduA:
undetectable
4zjzA-2cduA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvj THIOREDOXIN
REDUCTASE RELATED
PROTEIN


(Thermus
thermophilus)
PF00890
(FAD_binding_2)
PF07992
(Pyr_redox_2)
4 ALA A 141
GLY A 159
ALA A  16
GLY A  13
None
0.66A 4zjzA-2cvjA:
undetectable
4zjzA-2cvjA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gah HETEROTETRAMERIC
SARCOSINE OXIDASE
ALPHA-SUBUNIT


(Stenotrophomonas
maltophilia)
PF01571
(GCV_T)
PF07992
(Pyr_redox_2)
PF08669
(GCV_T_C)
PF13510
(Fer2_4)
4 ALA A 139
GLY A 417
ALA A 418
GLY A 250
NAD  A 999 (-3.2A)
NAD  A 999 (-3.2A)
NAD  A 999 (-3.8A)
NAD  A 999 (-3.3A)
0.54A 4zjzA-2gahA:
undetectable
4zjzA-2gahA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gah HETEROTETRAMERIC
SARCOSINE OXIDASE
ALPHA-SUBUNIT


(Stenotrophomonas
maltophilia)
PF01571
(GCV_T)
PF07992
(Pyr_redox_2)
PF08669
(GCV_T_C)
PF13510
(Fer2_4)
4 ALA A 416
GLY A 432
ALA A 143
GLY A 140
None
0.67A 4zjzA-2gahA:
undetectable
4zjzA-2gahA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po3 4-DEHYDRASE

(Streptomyces
venezuelae)
PF01041
(DegT_DnrJ_EryC1)
5 ALA A1209
VAL A1061
PHE A1196
GLY A1208
ALA A1076
None
None
None
None
T4K  A1500 ( 3.1A)
1.46A 4zjzA-2po3A:
3.8
4zjzA-2po3A:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q0l THIOREDOXIN
REDUCTASE


(Helicobacter
pylori)
PF07992
(Pyr_redox_2)
4 ALA A 279
GLY A 297
ALA A  16
GLY A  13
None
0.66A 4zjzA-2q0lA:
undetectable
4zjzA-2q0lA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q7v THIOREDOXIN
REDUCTASE


(Deinococcus
radiodurans)
PF07992
(Pyr_redox_2)
4 ALA A 282
GLY A 300
ALA A  23
GLY A  20
None
0.66A 4zjzA-2q7vA:
undetectable
4zjzA-2q7vA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qjj MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME


(Novosphingobium
aromaticivorans)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 GLY A 288
ALA A 289
GLY A 291
MET A  91
None
0.66A 4zjzA-2qjjA:
undetectable
4zjzA-2qjjA:
22.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2v7b BENZOATE-COENZYME A
LIGASE


(Paraburkholderia
xenovorans)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
5 ALA A 231
PRO A 261
PHE A 278
GLY A 280
MET A 288
None
0.55A 4zjzA-2v7bA:
62.1
4zjzA-2v7bA:
60.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vdc GLUTAMATE SYNTHASE
[NADPH] SMALL CHAIN


(Azospirillum
brasilense)
PF07992
(Pyr_redox_2)
PF14691
(Fer4_20)
4 ALA G 440
GLY G 457
ALA G 162
GLY G 159
None
0.68A 4zjzA-2vdcG:
undetectable
4zjzA-2vdcG:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w0p FILAMIN-A

(Homo sapiens)
PF00630
(Filamin)
5 ALA A2266
VAL A2241
GLY A2267
ALA A2268
GLY A2269
None
1.28A 4zjzA-2w0pA:
undetectable
4zjzA-2w0pA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x4g NUCLEOSIDE-DIPHOSPHA
TE-SUGAR EPIMERASE


(Pseudomonas
aeruginosa)
PF01370
(Epimerase)
5 ALA A 221
VAL A 183
GLY A 222
ALA A  28
GLY A  25
None
1.17A 4zjzA-2x4gA:
3.9
4zjzA-2x4gA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zxh TRNA URIDINE
5-CARBOXYMETHYLAMINO
METHYL MODIFICATION
ENZYME MNMG


(Aquifex
aeolicus)
PF01134
(GIDA)
PF13932
(GIDA_assoc)
4 ALA A 375
GLY A 391
ALA A  22
GLY A  19
None
0.66A 4zjzA-2zxhA:
undetectable
4zjzA-2zxhA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cty THIOREDOXIN
REDUCTASE


(Thermoplasma
acidophilum)
PF07992
(Pyr_redox_2)
4 ALA A 286
GLY A 304
ALA A  31
GLY A  28
None
0.67A 4zjzA-3ctyA:
undetectable
4zjzA-3ctyA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egl DEGV FAMILY PROTEIN

(Corynebacterium
glutamicum)
PF02645
(DegV)
5 ALA A 208
PHE A 206
ALA A 102
GLY A 104
MET A 108
None
1.03A 4zjzA-3eglA:
4.6
4zjzA-3eglA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egl DEGV FAMILY PROTEIN

(Corynebacterium
glutamicum)
PF02645
(DegV)
4 ALA A 208
VAL A 238
ALA A 102
GLY A 100
None
None
None
PLM  A 275 ( 4.2A)
0.55A 4zjzA-3eglA:
4.6
4zjzA-3eglA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eqn GLUCAN
1,3-BETA-GLUCOSIDASE


(Phanerochaete
chrysosporium)
PF12708
(Pectate_lyase_3)
4 ALA A 444
GLY A 476
ALA A 477
GLY A 479
None
0.64A 4zjzA-3eqnA:
undetectable
4zjzA-3eqnA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3es5 PUTATIVE CAPSID
PROTEIN


(Penicillium
stoloniferum
virus F)
no annotation 4 ALA A 121
VAL A 142
GLY A 182
GLY A 186
None
0.61A 4zjzA-3es5A:
undetectable
4zjzA-3es5A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g05 TRNA URIDINE
5-CARBOXYMETHYLAMINO
METHYL MODIFICATION
ENZYME MNMG


(Escherichia
coli)
PF01134
(GIDA)
PF13932
(GIDA_assoc)
4 ALA A 368
GLY A 384
ALA A  21
GLY A  18
None
None
None
SO4  A 551 (-4.8A)
0.69A 4zjzA-3g05A:
undetectable
4zjzA-3g05A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iha SALT-TOLERANT
GLUTAMINASE


(Micrococcus
luteus)
PF04960
(Glutaminase)
4 ALA A 119
VAL A 179
GLY A 116
ALA A 111
None
0.65A 4zjzA-3ihaA:
undetectable
4zjzA-3ihaA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ju8 SUCCINYLGLUTAMIC
SEMIALDEHYDE
DEHYDROGENASE


(Pseudomonas
aeruginosa)
PF00171
(Aldedh)
4 ALA A  47
GLY A 194
ALA A 193
GLY A   9
None
0.67A 4zjzA-3ju8A:
undetectable
4zjzA-3ju8A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jz4 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
[NADP+]


(Escherichia
coli)
PF00171
(Aldedh)
4 ALA A  55
GLY A 203
ALA A 202
GLY A  16
None
0.68A 4zjzA-3jz4A:
3.5
4zjzA-3jz4A:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kd9 COENZYME A DISULFIDE
REDUCTASE


(Pyrococcus
horikoshii)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 ALA A 278
GLY A 305
ALA A  18
GLY A  15
None
0.67A 4zjzA-3kd9A:
2.3
4zjzA-3kd9A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lg3 ISOCITRATE LYASE

(Yersinia pestis)
PF00463
(ICL)
5 ALA A 100
VAL A 121
ALA A  97
GLY A  93
MET A  91
None
1.39A 4zjzA-3lg3A:
undetectable
4zjzA-3lg3A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lt3 POSSIBLE
MEMBRANE-ASSOCIATED
SERINE PROTEASE


(Mycobacterium
tuberculosis)
PF13365
(Trypsin_2)
5 VAL A 331
PHE A 359
GLY A 360
ALA A 361
GLY A 369
None
1.21A 4zjzA-3lt3A:
undetectable
4zjzA-3lt3A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m6m RPFF PROTEIN

(Xanthomonas
campestris)
PF00378
(ECH_1)
5 ALA A 142
PHE A  44
GLY A 139
ALA A 135
MET A  31
None
0.85A 4zjzA-3m6mA:
undetectable
4zjzA-3m6mA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ml0 PENICILLIN G
ACYLASE, ALPHA
SUBUNIT


(Alcaligenes
faecalis)
PF01804
(Penicil_amidase)
4 ALA A  32
PRO A  15
VAL A   7
GLY A  30
None
0.64A 4zjzA-3ml0A:
undetectable
4zjzA-3ml0A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nks PROTOPORPHYRINOGEN
OXIDASE


(Homo sapiens)
PF01593
(Amino_oxidase)
4 ALA A 447
GLY A 463
ALA A  17
GLY A  14
None
0.64A 4zjzA-3nksA:
undetectable
4zjzA-3nksA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3npe 9-CIS-EPOXYCAROTENOI
D DIOXYGENASE 1,
CHLOROPLASTIC


(Zea mays)
PF03055
(RPE65)
4 ALA A 117
PRO A 114
GLY A 216
GLY A 220
None
0.65A 4zjzA-3npeA:
undetectable
4zjzA-3npeA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE


(Cytophaga
hutchinsonii)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 ALA A 352
VAL A 330
ALA A 303
GLY A 300
None
0.65A 4zjzA-3q4dA:
1.4
4zjzA-3q4dA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r9u THIOREDOXIN
REDUCTASE


(Campylobacter
jejuni)
PF07992
(Pyr_redox_2)
4 ALA A 279
GLY A 297
ALA A  16
GLY A  13
None
0.62A 4zjzA-3r9uA:
undetectable
4zjzA-3r9uA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr5 PEPTIDE CHAIN
RELEASE FACTOR 3


(Coxiella
burnetii)
PF00009
(GTP_EFTU)
PF16658
(RF3_C)
4 ALA A 317
VAL A 285
PHE A 383
GLY A 294
None
0.58A 4zjzA-3tr5A:
undetectable
4zjzA-3tr5A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ty7 PUTATIVE ALDEHYDE
DEHYDROGENASE
SAV2122


(Staphylococcus
aureus)
PF00171
(Aldedh)
5 ALA A 160
VAL A 167
GLY A 164
ALA A 136
GLY A 138
None
1.26A 4zjzA-3ty7A:
2.5
4zjzA-3ty7A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4at0 3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E


(Rhodococcus
jostii)
PF00890
(FAD_binding_2)
4 ALA A 454
GLY A 479
ALA A  36
GLY A  33
None
0.65A 4zjzA-4at0A:
undetectable
4zjzA-4at0A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bvl PHB DEPOLYMERASE
PHAZ7


(Paucimonas
lemoignei)
PF01674
(Lipase_2)
5 ALA A 276
VAL A  63
GLY A 275
ALA A 238
GLY A 305
None
1.14A 4zjzA-4bvlA:
4.1
4zjzA-4bvlA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c2k 3-KETOACYL-COA
THIOLASE,
MITOCHONDRIAL


(Homo sapiens)
PF00108
(Thiolase_N)
PF02803
(Thiolase_C)
4 VAL A 208
GLY A  18
ALA A  19
GLY A  22
None
0.63A 4zjzA-4c2kA:
undetectable
4zjzA-4c2kA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cnk L-AMINO ACID OXIDASE

(Streptococcus
cristatus)
PF03486
(HI0933_like)
4 ALA A 360
GLY A 382
ALA A  18
GLY A  15
None
0.67A 4zjzA-4cnkA:
undetectable
4zjzA-4cnkA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g97 RESPONSE REGULATOR
RECEIVER


(Brucella
abortus)
PF00072
(Response_reg)
5 ALA A 190
VAL A 215
PHE A 217
GLY A 200
ALA A 203
None
1.07A 4zjzA-4g97A:
5.1
4zjzA-4g97A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gcm THIOREDOXIN
REDUCTASE


(Staphylococcus
aureus)
PF07992
(Pyr_redox_2)
4 ALA A 275
GLY A 293
ALA A  20
GLY A  17
None
0.67A 4zjzA-4gcmA:
undetectable
4zjzA-4gcmA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4guc PROTEIN BA_2500

(Bacillus
anthracis)
PF16723
(DUF5065)
4 ALA A 138
VAL A  90
PHE A  76
ALA A  66
None
0.70A 4zjzA-4gucA:
undetectable
4zjzA-4gucA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B


(Homo sapiens)
PF01593
(Amino_oxidase)
PF04433
(SWIRM)
PF07496
(zf-CW)
4 ALA A 793
GLY A 812
ALA A 397
GLY A 394
None
0.66A 4zjzA-4hsuA:
undetectable
4zjzA-4hsuA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iv5 ASPARTATE
CARBAMOYLTRANSFERASE
, PUTATIVE


(Trypanosoma
cruzi)
PF00185
(OTCace)
PF02729
(OTCace_N)
4 PRO A 203
GLY A 139
ALA A 138
GLY A 173
None
0.64A 4zjzA-4iv5A:
4.3
4zjzA-4iv5A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jnq THIOREDOXIN
REDUCTASE


(Brucella
melitensis)
PF07992
(Pyr_redox_2)
4 ALA A 284
GLY A 302
ALA A  20
GLY A  17
None
0.63A 4zjzA-4jnqA:
undetectable
4zjzA-4jnqA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4knt MULTICOPPER OXIDASE
TYPE 1


(Nitrosomonas
europaea)
PF07732
(Cu-oxidase_3)
4 PHE A 120
GLY A 257
ALA A 256
GLY A 219
CU  A 407 ( 4.9A)
None
None
None
0.68A 4zjzA-4kntA:
undetectable
4zjzA-4kntA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC


(Shewanella
oneidensis)
PF14522
(Cytochrome_C7)
5 ALA A 385
PRO A 544
VAL A 539
PHE A 436
GLY A 381
None
1.06A 4zjzA-4lm8A:
undetectable
4zjzA-4lm8A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o6r ALDEHYDE
DEHYDROGENASE


(Burkholderia
cenocepacia)
PF00171
(Aldedh)
4 ALA A  48
GLY A 196
ALA A 195
GLY A   9
None
0.69A 4zjzA-4o6rA:
3.3
4zjzA-4o6rA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o9x TCDB2, TCCC3

(Photorhabdus
luminescens)
PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN)
4 ALA A1626
GLY A1608
ALA A1607
GLY A1968
None
0.65A 4zjzA-4o9xA:
undetectable
4zjzA-4o9xA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxl CYTOSOLIC ALDEHYDE
DEHYDROGENASE RF2C


(Zea mays)
PF00171
(Aldedh)
4 ALA A  67
GLY A 217
ALA A 216
GLY A  28
None
0.70A 4zjzA-4pxlA:
undetectable
4zjzA-4pxlA:
22.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4rlq BENZOATE-COENZYME A
LIGASE


(Rhodopseudomonas
palustris)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
8 ALA A 221
PRO A 251
VAL A 256
PHE A 272
GLY A 274
ALA A 275
GLY A 278
MET A 282
None
0.09A 4zjzA-4rlqA:
72.7
4zjzA-4rlqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wv3 ANTHRANILATE-COA
LIGASE


(Stigmatella
aurantiaca)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
4 VAL A 251
PHE A 263
ALA A 266
GLY A 269
None
0.54A 4zjzA-4wv3A:
57.8
4zjzA-4wv3A:
42.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xvg ALKYL HYDROPEROXIDE
REDUCTASE SUBUNIT F


(Escherichia
coli)
PF07992
(Pyr_redox_2)
PF13192
(Thioredoxin_3)
4 ALA A 486
GLY A 504
ALA A 227
GLY A 224
None
0.67A 4zjzA-4xvgA:
undetectable
4zjzA-4xvgA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ywe PUTATIVE ALDEHYDE
DEHYDROGENASE


(Burkholderia
cenocepacia)
PF00171
(Aldedh)
4 ALA A  49
GLY A 197
ALA A 196
GLY A  10
None
0.68A 4zjzA-4yweA:
undetectable
4zjzA-4yweA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ywo MERCURIC REDUCTASE

(Metallosphaera
sedula)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 ALA A 290
GLY A 307
ALA A  16
GLY A  13
None
0.66A 4zjzA-4ywoA:
undetectable
4zjzA-4ywoA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5afu DYNACTIN

(Sus scrofa)
PF00022
(Actin)
4 ALA A 348
PRO A  11
VAL A  13
GLY A  27
None
0.69A 4zjzA-5afuA:
undetectable
4zjzA-5afuA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ez3 ACYL-COA
DEHYDROGENASE


(Brucella
melitensis)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
4 ALA A 503
PHE A 519
GLY A 358
ALA A 359
None
0.70A 4zjzA-5ez3A:
undetectable
4zjzA-5ez3A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fus PUTATIVE ENOYL COA
HYDRATASE


(Burkholderia
cenocepacia)
PF00378
(ECH_1)
4 ALA A 139
PHE A  44
GLY A 136
ALA A 132
DAO  A1285 ( 4.0A)
DAO  A1285 (-3.5A)
None
None
0.65A 4zjzA-5fusA:
undetectable
4zjzA-5fusA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g4g VCP-LIKE ATPASE

(Thermoplasma
acidophilum)
PF00004
(AAA)
PF02359
(CDC48_N)
PF02933
(CDC48_2)
4 ALA A 686
VAL A 658
PHE A 701
GLY A 683
None
0.65A 4zjzA-5g4gA:
2.3
4zjzA-5g4gA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hx9 BETA-LACTAMASE

(Burkholderia
vietnamiensis)
PF13354
(Beta-lactamase2)
5 ALA A 281
VAL A 261
GLY A 224
ALA A 223
GLY A 220
None
1.43A 4zjzA-5hx9A:
undetectable
4zjzA-5hx9A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l3d LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1A


(Homo sapiens)
PF01593
(Amino_oxidase)
PF04433
(SWIRM)
4 ALA A 799
GLY A 818
ALA A 293
GLY A 290
None
0.68A 4zjzA-5l3dA:
undetectable
4zjzA-5l3dA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l46 DIMETHYLGLYCINE
DEHYDROGENASE,
MITOCHONDRIAL


(Homo sapiens)
PF01266
(DAO)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF16350
(FAO_M)
5 PRO A 737
VAL A 746
PHE A 754
GLY A 756
ALA A 759
None
1.07A 4zjzA-5l46A:
undetectable
4zjzA-5l46A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lae PEROXISOMAL
N(1)-ACETYL-SPERMINE
/SPERMIDINE
OXIDASE,PEROXISOMAL
N(1)-ACETYL-SPERMINE
/SPERMIDINE OXIDASE


(Mus musculus)
PF01593
(Amino_oxidase)
4 ALA A 463
GLY A 482
ALA A  20
GLY A  17
None
0.65A 4zjzA-5laeA:
undetectable
4zjzA-5laeA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lpc VANADIUM-DEPENDENT
BROMOPEROXIDASE


(Acaryochloris
marina)
no annotation 5 PRO A 152
VAL A 157
GLY A 606
ALA A 526
GLY A 420
None
1.08A 4zjzA-5lpcA:
undetectable
4zjzA-5lpcA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m5j THIOREDOXIN
REDUCTASE


(Giardia
intestinalis)
PF07992
(Pyr_redox_2)
4 ALA A 281
GLY A 299
ALA A  21
GLY A  18
None
0.69A 4zjzA-5m5jA:
undetectable
4zjzA-5m5jA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nii THIOREDOXIN
REDUCTASE


(Desulfovibrio
vulgaris)
no annotation 4 ALA A 264
GLY A 281
ALA A  18
GLY A  15
None
0.69A 4zjzA-5niiA:
undetectable
4zjzA-5niiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odr HETERODISULFIDE
REDUCTASE, SUBUNIT A


(Methanothermococcus
thermolithotrophicus)
PF07992
(Pyr_redox_2)
PF13187
(Fer4_9)
4 ALA A 154
GLY A 539
ALA A 540
GLY A 329
FAD  A 701 (-3.4A)
FAD  A 701 (-3.2A)
FAD  A 701 (-3.8A)
FAD  A 701 (-3.1A)
0.51A 4zjzA-5odrA:
3.2
4zjzA-5odrA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odr HETERODISULFIDE
REDUCTASE, SUBUNIT A


(Methanothermococcus
thermolithotrophicus)
PF07992
(Pyr_redox_2)
PF13187
(Fer4_9)
4 VAL A  68
PHE A  80
ALA A  47
GLY A  50
None
0.66A 4zjzA-5odrA:
3.2
4zjzA-5odrA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5td3 CATECHOL
1,2-DIOXYGENASE


(Burkholderia
vietnamiensis)
PF00775
(Dioxygenase_C)
PF04444
(Dioxygenase_N)
5 PRO A 144
VAL A 146
GLY A 286
ALA A 283
GLY A 282
None
1.12A 4zjzA-5td3A:
undetectable
4zjzA-5td3A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ts5 AMINE OXIDASE

(Bothrops atrox)
PF01593
(Amino_oxidase)
4 ALA A 455
GLY A 473
ALA A  48
GLY A  45
None
0.68A 4zjzA-5ts5A:
undetectable
4zjzA-5ts5A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u63 THIOREDOXIN
REDUCTASE


(Haemophilus
influenzae)
PF07992
(Pyr_redox_2)
4 ALA A 284
GLY A 302
ALA A  21
GLY A  18
None
0.65A 4zjzA-5u63A:
undetectable
4zjzA-5u63A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5usx THIOREDOXIN
REDUCTASE


(Vibrio
vulnificus)
PF07992
(Pyr_redox_2)
4 ALA A 284
GLY A 302
ALA A  21
GLY A  18
None
0.68A 4zjzA-5usxA:
undetectable
4zjzA-5usxA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uth THIOREDOXIN
REDUCTASE


(Mycolicibacterium
smegmatis)
PF07992
(Pyr_redox_2)
4 ALA A 278
GLY A 296
ALA A  22
GLY A  19
None
0.63A 4zjzA-5uthA:
undetectable
4zjzA-5uthA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uxv SENSORY TRANSDUCTION
REGULATORY PROTEIN


(Bartonella
quintana)
no annotation 5 ALA A 190
VAL A 215
PHE A 217
GLY A 200
ALA A 203
None
1.07A 4zjzA-5uxvA:
4.7
4zjzA-5uxvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5voh NADH OXIDASE

(Lactobacillus
brevis)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 ALA A 277
GLY A 304
ALA A  15
GLY A  12
None
0.65A 4zjzA-5vohA:
undetectable
4zjzA-5vohA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w4c THIOREDOXIN
REDUCTASE


(Cryptococcus
neoformans)
no annotation 4 ALA A 314
GLY A 332
ALA A  45
GLY A  42
None
0.70A 4zjzA-5w4cA:
undetectable
4zjzA-5w4cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x5t ALPHA-KETOGLUTARIC
SEMIALDEHYDE
DEHYDROGENASE


(Azospirillum
brasilense)
PF00171
(Aldedh)
4 ALA A  54
GLY A 202
ALA A 201
GLY A  15
None
0.68A 4zjzA-5x5tA:
undetectable
4zjzA-5x5tA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z2g L-AMINO ACID OXIDASE

(Naja atra)
no annotation 4 ALA A 471
GLY A 489
ALA A  67
GLY A  64
None
0.70A 4zjzA-5z2gA:
undetectable
4zjzA-5z2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bwt THIOREDOXIN
REDUCTASE


(Francisella
tularensis)
no annotation 4 ALA A 282
GLY A 300
ALA A  19
GLY A  16
None
0.66A 4zjzA-6bwtA:
undetectable
4zjzA-6bwtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d9y SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR


(Paraburkholderia
phymatum)
no annotation 4 ALA A 162
GLY A 147
ALA A 146
GLY A 150
None
0.68A 4zjzA-6d9yA:
undetectable
4zjzA-6d9yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f8y THREONYLCARBAMOYL-AM
P SYNTHASE


(Pyrococcus
abyssi)
no annotation 4 ALA A 141
PHE A  31
GLY A  40
ALA A  41
THR  A 401 (-4.7A)
None
None
None
0.69A 4zjzA-6f8yA:
2.1
4zjzA-6f8yA:
undetectable