SIMILAR PATTERNS OF AMINO ACIDS FOR 4ZJZ_A_BEZA1001
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d4e | FLAVOCYTOCHROME CFUMARATE REDUCTASE (Shewanellaoneidensis) |
PF00890(FAD_binding_2)PF14537(Cytochrom_c3_2) | 4 | ALA A 532GLY A 557ALA A 140GLY A 137 | None | 0.69A | 4zjzA-1d4eA:undetectable | 4zjzA-1d4eA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f8r | L-AMINO ACID OXIDASE (Calloselasmarhodostoma) |
PF01593(Amino_oxidase) | 4 | ALA A 455GLY A 473ALA A 48GLY A 45 | None | 0.70A | 4zjzA-1f8rA:undetectable | 4zjzA-1f8rA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fl2 | ALKYL HYDROPEROXIDEREDUCTASE SUBUNIT F (Escherichiacoli) |
PF07992(Pyr_redox_2) | 4 | ALA A 486GLY A 504ALA A 227GLY A 224 | None | 0.68A | 4zjzA-1fl2A:undetectable | 4zjzA-1fl2A:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gz2 | OVOCLEIDIN-17 (Gallus gallus) |
PF00059(Lectin_C) | 5 | ALA A 71VAL A 75PHE A 19GLY A 70ALA A 60 | NoneNoneNoneNoneSEP A 61 ( 3.7A) | 1.35A | 4zjzA-1gz2A:undetectable | 4zjzA-1gz2A:14.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j3b | ATP-DEPENDENTPHOSPHOENOLPYRUVATECARBOXYKINASE (Thermusthermophilus) |
PF01293(PEPCK_ATP) | 4 | VAL A 212PHE A 263GLY A 107ALA A 106 | None | 0.60A | 4zjzA-1j3bA:undetectable | 4zjzA-1j3bA:24.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m64 | FLAVOCYTOCHROME C3 (Shewanellafrigidimarina) |
PF00890(FAD_binding_2)PF14537(Cytochrom_c3_2) | 4 | ALA A 532GLY A 557ALA A 141GLY A 138 | None | 0.63A | 4zjzA-1m64A:undetectable | 4zjzA-1m64A:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mzj | BETA-KETOACYLSYNTHASE III (Streptomycessp. R1128) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | PRO A 335VAL A 302GLY A 18ALA A 71GLY A 16 | None | 1.04A | 4zjzA-1mzjA:undetectable | 4zjzA-1mzjA:23.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) |
PF01593(Amino_oxidase) | 4 | ALA A 466GLY A 482ALA A 28GLY A 25 | None | 0.68A | 4zjzA-1sezA:undetectable | 4zjzA-1sezA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tdf | THIOREDOXINREDUCTASE (Escherichiacoli) |
PF07992(Pyr_redox_2) | 4 | ALA A 284GLY A 302ALA A 20GLY A 17 | None | 0.63A | 4zjzA-1tdfA:undetectable | 4zjzA-1tdfA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tdk | L-AMINO ACID OXIDASE (Gloydius halys) |
PF01593(Amino_oxidase) | 4 | ALA A 455GLY A 473ALA A 48GLY A 45 | None | 0.68A | 4zjzA-1tdkA:undetectable | 4zjzA-1tdkA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v6a | L-LACTATEDEHYDROGENASE ACHAIN (Cyprinus carpio) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | ALA A 256VAL A 136GLY A 253ALA A 34GLY A 32 | None | 1.24A | 4zjzA-1v6aA:2.0 | 4zjzA-1v6aA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vrq | SARCOSINE OXIDASEALPHA SUBUNIT (Corynebacteriumsp. U-96) |
PF01571(GCV_T)PF08669(GCV_T_C)PF12831(FAD_oxidored)PF13510(Fer2_4) | 4 | ALA A 415GLY A 431ALA A 142GLY A 139 | None | 0.65A | 4zjzA-1vrqA:undetectable | 4zjzA-1vrqA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wnb | PUTATIVE BETAINEALDEHYDEDEHYDROGENASE (Escherichiacoli) |
PF00171(Aldedh) | 4 | ALA A 47GLY A 195ALA A 194GLY A 9 | None | 0.67A | 4zjzA-1wnbA:1.5 | 4zjzA-1wnbA:23.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wom | SIGMA FACTOR SIGBREGULATION PROTEINRSBQ (Bacillussubtilis) |
PF12697(Abhydrolase_6) | 4 | ALA A 24VAL A 78PHE A 92GLY A 94 | None | 0.55A | 4zjzA-1womA:3.9 | 4zjzA-1womA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xdi | RV3303C-LPDA (Mycobacteriumtuberculosis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | GLY A 14ALA A 13GLY A 332MET A 336 | NoneFAD A 999 (-3.5A)NoneNone | 0.65A | 4zjzA-1xdiA:undetectable | 4zjzA-1xdiA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y56 | HYPOTHETICAL PROTEINPH1363 (Pyrococcushorikoshii) |
PF07992(Pyr_redox_2)PF13510(Fer2_4) | 4 | ALA A 347GLY A 363ALA A 121GLY A 118 | None | 0.62A | 4zjzA-1y56A:undetectable | 4zjzA-1y56A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ytl | ACETYL-COADECARBOXYLASE/SYNTHASE COMPLEX EPSILONSUBUNIT 2 (Archaeoglobusfulgidus) |
PF02552(CO_dh) | 4 | VAL A 54PHE A 74GLY A 43MET A 46 | None | 0.69A | 4zjzA-1ytlA:3.3 | 4zjzA-1ytlA:17.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yy5 | FMS1 PROTEIN (Saccharomycescerevisiae) |
PF01593(Amino_oxidase) | 4 | ALA A 477GLY A 496ALA A 23GLY A 20 | None | 0.69A | 4zjzA-1yy5A:undetectable | 4zjzA-1yy5A:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a87 | THIOREDOXINREDUCTASE (Mycobacteriumtuberculosis) |
PF07992(Pyr_redox_2) | 4 | ALA A 286GLY A 304ALA A 29GLY A 26 | None | 0.69A | 4zjzA-2a87A:undetectable | 4zjzA-2a87A:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2adv | GLUTARYL 7-AMINOCEPHALOSPORANICACID ACYLASE (Pseudomonas sp.SY-77-1) |
PF01804(Penicil_amidase) | 5 | PRO C 379PHE C 355GLY C 365ALA C 364GLY C 362 | None | 1.29A | 4zjzA-2advC:undetectable | 4zjzA-2advC:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ag1 | BENZALDEHYDE LYASE (Pseudomonasfluorescens) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | ALA A 431VAL A 390GLY A 59ALA A 56GLY A 426 | None | 0.93A | 4zjzA-2ag1A:3.1 | 4zjzA-2ag1A:25.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cdu | NADPH OXIDASE (Lactobacillussanfranciscensis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | ALA A 280GLY A 307ALA A 15GLY A 12 | None | 0.67A | 4zjzA-2cduA:undetectable | 4zjzA-2cduA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cvj | THIOREDOXINREDUCTASE RELATEDPROTEIN (Thermusthermophilus) |
PF00890(FAD_binding_2)PF07992(Pyr_redox_2) | 4 | ALA A 141GLY A 159ALA A 16GLY A 13 | None | 0.66A | 4zjzA-2cvjA:undetectable | 4zjzA-2cvjA:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gah | HETEROTETRAMERICSARCOSINE OXIDASEALPHA-SUBUNIT (Stenotrophomonasmaltophilia) |
PF01571(GCV_T)PF07992(Pyr_redox_2)PF08669(GCV_T_C)PF13510(Fer2_4) | 4 | ALA A 139GLY A 417ALA A 418GLY A 250 | NAD A 999 (-3.2A)NAD A 999 (-3.2A)NAD A 999 (-3.8A)NAD A 999 (-3.3A) | 0.54A | 4zjzA-2gahA:undetectable | 4zjzA-2gahA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gah | HETEROTETRAMERICSARCOSINE OXIDASEALPHA-SUBUNIT (Stenotrophomonasmaltophilia) |
PF01571(GCV_T)PF07992(Pyr_redox_2)PF08669(GCV_T_C)PF13510(Fer2_4) | 4 | ALA A 416GLY A 432ALA A 143GLY A 140 | None | 0.67A | 4zjzA-2gahA:undetectable | 4zjzA-2gahA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2po3 | 4-DEHYDRASE (Streptomycesvenezuelae) |
PF01041(DegT_DnrJ_EryC1) | 5 | ALA A1209VAL A1061PHE A1196GLY A1208ALA A1076 | NoneNoneNoneNoneT4K A1500 ( 3.1A) | 1.46A | 4zjzA-2po3A:3.8 | 4zjzA-2po3A:24.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q0l | THIOREDOXINREDUCTASE (Helicobacterpylori) |
PF07992(Pyr_redox_2) | 4 | ALA A 279GLY A 297ALA A 16GLY A 13 | None | 0.66A | 4zjzA-2q0lA:undetectable | 4zjzA-2q0lA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q7v | THIOREDOXINREDUCTASE (Deinococcusradiodurans) |
PF07992(Pyr_redox_2) | 4 | ALA A 282GLY A 300ALA A 23GLY A 20 | None | 0.66A | 4zjzA-2q7vA:undetectable | 4zjzA-2q7vA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qjj | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Novosphingobiumaromaticivorans) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | GLY A 288ALA A 289GLY A 291MET A 91 | None | 0.66A | 4zjzA-2qjjA:undetectable | 4zjzA-2qjjA:22.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2v7b | BENZOATE-COENZYME ALIGASE (Paraburkholderiaxenovorans) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 5 | ALA A 231PRO A 261PHE A 278GLY A 280MET A 288 | None | 0.55A | 4zjzA-2v7bA:62.1 | 4zjzA-2v7bA:60.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vdc | GLUTAMATE SYNTHASE[NADPH] SMALL CHAIN (Azospirillumbrasilense) |
PF07992(Pyr_redox_2)PF14691(Fer4_20) | 4 | ALA G 440GLY G 457ALA G 162GLY G 159 | None | 0.68A | 4zjzA-2vdcG:undetectable | 4zjzA-2vdcG:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w0p | FILAMIN-A (Homo sapiens) |
PF00630(Filamin) | 5 | ALA A2266VAL A2241GLY A2267ALA A2268GLY A2269 | None | 1.28A | 4zjzA-2w0pA:undetectable | 4zjzA-2w0pA:12.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x4g | NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE (Pseudomonasaeruginosa) |
PF01370(Epimerase) | 5 | ALA A 221VAL A 183GLY A 222ALA A 28GLY A 25 | None | 1.17A | 4zjzA-2x4gA:3.9 | 4zjzA-2x4gA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zxh | TRNA URIDINE5-CARBOXYMETHYLAMINOMETHYL MODIFICATIONENZYME MNMG (Aquifexaeolicus) |
PF01134(GIDA)PF13932(GIDA_assoc) | 4 | ALA A 375GLY A 391ALA A 22GLY A 19 | None | 0.66A | 4zjzA-2zxhA:undetectable | 4zjzA-2zxhA:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cty | THIOREDOXINREDUCTASE (Thermoplasmaacidophilum) |
PF07992(Pyr_redox_2) | 4 | ALA A 286GLY A 304ALA A 31GLY A 28 | None | 0.67A | 4zjzA-3ctyA:undetectable | 4zjzA-3ctyA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3egl | DEGV FAMILY PROTEIN (Corynebacteriumglutamicum) |
PF02645(DegV) | 5 | ALA A 208PHE A 206ALA A 102GLY A 104MET A 108 | None | 1.03A | 4zjzA-3eglA:4.6 | 4zjzA-3eglA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3egl | DEGV FAMILY PROTEIN (Corynebacteriumglutamicum) |
PF02645(DegV) | 4 | ALA A 208VAL A 238ALA A 102GLY A 100 | NoneNoneNonePLM A 275 ( 4.2A) | 0.55A | 4zjzA-3eglA:4.6 | 4zjzA-3eglA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqn | GLUCAN1,3-BETA-GLUCOSIDASE (Phanerochaetechrysosporium) |
PF12708(Pectate_lyase_3) | 4 | ALA A 444GLY A 476ALA A 477GLY A 479 | None | 0.64A | 4zjzA-3eqnA:undetectable | 4zjzA-3eqnA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3es5 | PUTATIVE CAPSIDPROTEIN (Penicilliumstoloniferumvirus F) |
no annotation | 4 | ALA A 121VAL A 142GLY A 182GLY A 186 | None | 0.61A | 4zjzA-3es5A:undetectable | 4zjzA-3es5A:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g05 | TRNA URIDINE5-CARBOXYMETHYLAMINOMETHYL MODIFICATIONENZYME MNMG (Escherichiacoli) |
PF01134(GIDA)PF13932(GIDA_assoc) | 4 | ALA A 368GLY A 384ALA A 21GLY A 18 | NoneNoneNoneSO4 A 551 (-4.8A) | 0.69A | 4zjzA-3g05A:undetectable | 4zjzA-3g05A:23.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iha | SALT-TOLERANTGLUTAMINASE (Micrococcusluteus) |
PF04960(Glutaminase) | 4 | ALA A 119VAL A 179GLY A 116ALA A 111 | None | 0.65A | 4zjzA-3ihaA:undetectable | 4zjzA-3ihaA:24.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ju8 | SUCCINYLGLUTAMICSEMIALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00171(Aldedh) | 4 | ALA A 47GLY A 194ALA A 193GLY A 9 | None | 0.67A | 4zjzA-3ju8A:undetectable | 4zjzA-3ju8A:24.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jz4 | SUCCINATE-SEMIALDEHYDE DEHYDROGENASE[NADP+] (Escherichiacoli) |
PF00171(Aldedh) | 4 | ALA A 55GLY A 203ALA A 202GLY A 16 | None | 0.68A | 4zjzA-3jz4A:3.5 | 4zjzA-3jz4A:24.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kd9 | COENZYME A DISULFIDEREDUCTASE (Pyrococcushorikoshii) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | ALA A 278GLY A 305ALA A 18GLY A 15 | None | 0.67A | 4zjzA-3kd9A:2.3 | 4zjzA-3kd9A:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lg3 | ISOCITRATE LYASE (Yersinia pestis) |
PF00463(ICL) | 5 | ALA A 100VAL A 121ALA A 97GLY A 93MET A 91 | None | 1.39A | 4zjzA-3lg3A:undetectable | 4zjzA-3lg3A:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lt3 | POSSIBLEMEMBRANE-ASSOCIATEDSERINE PROTEASE (Mycobacteriumtuberculosis) |
PF13365(Trypsin_2) | 5 | VAL A 331PHE A 359GLY A 360ALA A 361GLY A 369 | None | 1.21A | 4zjzA-3lt3A:undetectable | 4zjzA-3lt3A:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m6m | RPFF PROTEIN (Xanthomonascampestris) |
PF00378(ECH_1) | 5 | ALA A 142PHE A 44GLY A 139ALA A 135MET A 31 | None | 0.85A | 4zjzA-3m6mA:undetectable | 4zjzA-3m6mA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ml0 | PENICILLIN GACYLASE, ALPHASUBUNIT (Alcaligenesfaecalis) |
PF01804(Penicil_amidase) | 4 | ALA A 32PRO A 15VAL A 7GLY A 30 | None | 0.64A | 4zjzA-3ml0A:undetectable | 4zjzA-3ml0A:17.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nks | PROTOPORPHYRINOGENOXIDASE (Homo sapiens) |
PF01593(Amino_oxidase) | 4 | ALA A 447GLY A 463ALA A 17GLY A 14 | None | 0.64A | 4zjzA-3nksA:undetectable | 4zjzA-3nksA:24.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3npe | 9-CIS-EPOXYCAROTENOID DIOXYGENASE 1,CHLOROPLASTIC (Zea mays) |
PF03055(RPE65) | 4 | ALA A 117PRO A 114GLY A 216GLY A 220 | None | 0.65A | 4zjzA-3npeA:undetectable | 4zjzA-3npeA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q4d | MANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY POSSIBLECHLOROMUCONATECYCLOISOMERASE (Cytophagahutchinsonii) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ALA A 352VAL A 330ALA A 303GLY A 300 | None | 0.65A | 4zjzA-3q4dA:1.4 | 4zjzA-3q4dA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r9u | THIOREDOXINREDUCTASE (Campylobacterjejuni) |
PF07992(Pyr_redox_2) | 4 | ALA A 279GLY A 297ALA A 16GLY A 13 | None | 0.62A | 4zjzA-3r9uA:undetectable | 4zjzA-3r9uA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tr5 | PEPTIDE CHAINRELEASE FACTOR 3 (Coxiellaburnetii) |
PF00009(GTP_EFTU)PF16658(RF3_C) | 4 | ALA A 317VAL A 285PHE A 383GLY A 294 | None | 0.58A | 4zjzA-3tr5A:undetectable | 4zjzA-3tr5A:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ty7 | PUTATIVE ALDEHYDEDEHYDROGENASESAV2122 (Staphylococcusaureus) |
PF00171(Aldedh) | 5 | ALA A 160VAL A 167GLY A 164ALA A 136GLY A 138 | None | 1.26A | 4zjzA-3ty7A:2.5 | 4zjzA-3ty7A:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4at0 | 3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE (Rhodococcusjostii) |
PF00890(FAD_binding_2) | 4 | ALA A 454GLY A 479ALA A 36GLY A 33 | None | 0.65A | 4zjzA-4at0A:undetectable | 4zjzA-4at0A:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bvl | PHB DEPOLYMERASEPHAZ7 (Paucimonaslemoignei) |
PF01674(Lipase_2) | 5 | ALA A 276VAL A 63GLY A 275ALA A 238GLY A 305 | None | 1.14A | 4zjzA-4bvlA:4.1 | 4zjzA-4bvlA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c2k | 3-KETOACYL-COATHIOLASE,MITOCHONDRIAL (Homo sapiens) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 4 | VAL A 208GLY A 18ALA A 19GLY A 22 | None | 0.63A | 4zjzA-4c2kA:undetectable | 4zjzA-4c2kA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cnk | L-AMINO ACID OXIDASE (Streptococcuscristatus) |
PF03486(HI0933_like) | 4 | ALA A 360GLY A 382ALA A 18GLY A 15 | None | 0.67A | 4zjzA-4cnkA:undetectable | 4zjzA-4cnkA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g97 | RESPONSE REGULATORRECEIVER (Brucellaabortus) |
PF00072(Response_reg) | 5 | ALA A 190VAL A 215PHE A 217GLY A 200ALA A 203 | None | 1.07A | 4zjzA-4g97A:5.1 | 4zjzA-4g97A:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gcm | THIOREDOXINREDUCTASE (Staphylococcusaureus) |
PF07992(Pyr_redox_2) | 4 | ALA A 275GLY A 293ALA A 20GLY A 17 | None | 0.67A | 4zjzA-4gcmA:undetectable | 4zjzA-4gcmA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4guc | PROTEIN BA_2500 (Bacillusanthracis) |
PF16723(DUF5065) | 4 | ALA A 138VAL A 90PHE A 76ALA A 66 | None | 0.70A | 4zjzA-4gucA:undetectable | 4zjzA-4gucA:13.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hsu | LYSINE-SPECIFICHISTONE DEMETHYLASE1B (Homo sapiens) |
PF01593(Amino_oxidase)PF04433(SWIRM)PF07496(zf-CW) | 4 | ALA A 793GLY A 812ALA A 397GLY A 394 | None | 0.66A | 4zjzA-4hsuA:undetectable | 4zjzA-4hsuA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iv5 | ASPARTATECARBAMOYLTRANSFERASE, PUTATIVE (Trypanosomacruzi) |
PF00185(OTCace)PF02729(OTCace_N) | 4 | PRO A 203GLY A 139ALA A 138GLY A 173 | None | 0.64A | 4zjzA-4iv5A:4.3 | 4zjzA-4iv5A:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jnq | THIOREDOXINREDUCTASE (Brucellamelitensis) |
PF07992(Pyr_redox_2) | 4 | ALA A 284GLY A 302ALA A 20GLY A 17 | None | 0.63A | 4zjzA-4jnqA:undetectable | 4zjzA-4jnqA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4knt | MULTICOPPER OXIDASETYPE 1 (Nitrosomonaseuropaea) |
PF07732(Cu-oxidase_3) | 4 | PHE A 120GLY A 257ALA A 256GLY A 219 | CU A 407 ( 4.9A)NoneNoneNone | 0.68A | 4zjzA-4kntA:undetectable | 4zjzA-4kntA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lm8 | EXTRACELLULAR IRONOXIDE RESPIRATORYSYSTEM SURFACEDECAHEME CYTOCHROMEC COMPONENT MTRC (Shewanellaoneidensis) |
PF14522(Cytochrome_C7) | 5 | ALA A 385PRO A 544VAL A 539PHE A 436GLY A 381 | None | 1.06A | 4zjzA-4lm8A:undetectable | 4zjzA-4lm8A:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o6r | ALDEHYDEDEHYDROGENASE (Burkholderiacenocepacia) |
PF00171(Aldedh) | 4 | ALA A 48GLY A 196ALA A 195GLY A 9 | None | 0.69A | 4zjzA-4o6rA:3.3 | 4zjzA-4o6rA:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o9x | TCDB2, TCCC3 (Photorhabdusluminescens) |
PF03534(SpvB)PF12255(TcdB_toxin_midC)PF12256(TcdB_toxin_midN) | 4 | ALA A1626GLY A1608ALA A1607GLY A1968 | None | 0.65A | 4zjzA-4o9xA:undetectable | 4zjzA-4o9xA:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxl | CYTOSOLIC ALDEHYDEDEHYDROGENASE RF2C (Zea mays) |
PF00171(Aldedh) | 4 | ALA A 67GLY A 217ALA A 216GLY A 28 | None | 0.70A | 4zjzA-4pxlA:undetectable | 4zjzA-4pxlA:22.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4rlq | BENZOATE-COENZYME ALIGASE (Rhodopseudomonaspalustris) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 8 | ALA A 221PRO A 251VAL A 256PHE A 272GLY A 274ALA A 275GLY A 278MET A 282 | None | 0.09A | 4zjzA-4rlqA:72.7 | 4zjzA-4rlqA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4wv3 | ANTHRANILATE-COALIGASE (Stigmatellaaurantiaca) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | VAL A 251PHE A 263ALA A 266GLY A 269 | None | 0.54A | 4zjzA-4wv3A:57.8 | 4zjzA-4wv3A:42.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xvg | ALKYL HYDROPEROXIDEREDUCTASE SUBUNIT F (Escherichiacoli) |
PF07992(Pyr_redox_2)PF13192(Thioredoxin_3) | 4 | ALA A 486GLY A 504ALA A 227GLY A 224 | None | 0.67A | 4zjzA-4xvgA:undetectable | 4zjzA-4xvgA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ywe | PUTATIVE ALDEHYDEDEHYDROGENASE (Burkholderiacenocepacia) |
PF00171(Aldedh) | 4 | ALA A 49GLY A 197ALA A 196GLY A 10 | None | 0.68A | 4zjzA-4yweA:undetectable | 4zjzA-4yweA:23.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ywo | MERCURIC REDUCTASE (Metallosphaerasedula) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | ALA A 290GLY A 307ALA A 16GLY A 13 | None | 0.66A | 4zjzA-4ywoA:undetectable | 4zjzA-4ywoA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5afu | DYNACTIN (Sus scrofa) |
PF00022(Actin) | 4 | ALA A 348PRO A 11VAL A 13GLY A 27 | None | 0.69A | 4zjzA-5afuA:undetectable | 4zjzA-5afuA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ez3 | ACYL-COADEHYDROGENASE (Brucellamelitensis) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M) | 4 | ALA A 503PHE A 519GLY A 358ALA A 359 | None | 0.70A | 4zjzA-5ez3A:undetectable | 4zjzA-5ez3A:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fus | PUTATIVE ENOYL COAHYDRATASE (Burkholderiacenocepacia) |
PF00378(ECH_1) | 4 | ALA A 139PHE A 44GLY A 136ALA A 132 | DAO A1285 ( 4.0A)DAO A1285 (-3.5A)NoneNone | 0.65A | 4zjzA-5fusA:undetectable | 4zjzA-5fusA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g4g | VCP-LIKE ATPASE (Thermoplasmaacidophilum) |
PF00004(AAA)PF02359(CDC48_N)PF02933(CDC48_2) | 4 | ALA A 686VAL A 658PHE A 701GLY A 683 | None | 0.65A | 4zjzA-5g4gA:2.3 | 4zjzA-5g4gA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hx9 | BETA-LACTAMASE (Burkholderiavietnamiensis) |
PF13354(Beta-lactamase2) | 5 | ALA A 281VAL A 261GLY A 224ALA A 223GLY A 220 | None | 1.43A | 4zjzA-5hx9A:undetectable | 4zjzA-5hx9A:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l3d | LYSINE-SPECIFICHISTONE DEMETHYLASE1A (Homo sapiens) |
PF01593(Amino_oxidase)PF04433(SWIRM) | 4 | ALA A 799GLY A 818ALA A 293GLY A 290 | None | 0.68A | 4zjzA-5l3dA:undetectable | 4zjzA-5l3dA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l46 | DIMETHYLGLYCINEDEHYDROGENASE,MITOCHONDRIAL (Homo sapiens) |
PF01266(DAO)PF01571(GCV_T)PF08669(GCV_T_C)PF16350(FAO_M) | 5 | PRO A 737VAL A 746PHE A 754GLY A 756ALA A 759 | None | 1.07A | 4zjzA-5l46A:undetectable | 4zjzA-5l46A:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lae | PEROXISOMALN(1)-ACETYL-SPERMINE/SPERMIDINEOXIDASE,PEROXISOMALN(1)-ACETYL-SPERMINE/SPERMIDINE OXIDASE (Mus musculus) |
PF01593(Amino_oxidase) | 4 | ALA A 463GLY A 482ALA A 20GLY A 17 | None | 0.65A | 4zjzA-5laeA:undetectable | 4zjzA-5laeA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lpc | VANADIUM-DEPENDENTBROMOPEROXIDASE (Acaryochlorismarina) |
no annotation | 5 | PRO A 152VAL A 157GLY A 606ALA A 526GLY A 420 | None | 1.08A | 4zjzA-5lpcA:undetectable | 4zjzA-5lpcA:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m5j | THIOREDOXINREDUCTASE (Giardiaintestinalis) |
PF07992(Pyr_redox_2) | 4 | ALA A 281GLY A 299ALA A 21GLY A 18 | None | 0.69A | 4zjzA-5m5jA:undetectable | 4zjzA-5m5jA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nii | THIOREDOXINREDUCTASE (Desulfovibriovulgaris) |
no annotation | 4 | ALA A 264GLY A 281ALA A 18GLY A 15 | None | 0.69A | 4zjzA-5niiA:undetectable | 4zjzA-5niiA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5odr | HETERODISULFIDEREDUCTASE, SUBUNIT A (Methanothermococcusthermolithotrophicus) |
PF07992(Pyr_redox_2)PF13187(Fer4_9) | 4 | ALA A 154GLY A 539ALA A 540GLY A 329 | FAD A 701 (-3.4A)FAD A 701 (-3.2A)FAD A 701 (-3.8A)FAD A 701 (-3.1A) | 0.51A | 4zjzA-5odrA:3.2 | 4zjzA-5odrA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5odr | HETERODISULFIDEREDUCTASE, SUBUNIT A (Methanothermococcusthermolithotrophicus) |
PF07992(Pyr_redox_2)PF13187(Fer4_9) | 4 | VAL A 68PHE A 80ALA A 47GLY A 50 | None | 0.66A | 4zjzA-5odrA:3.2 | 4zjzA-5odrA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5td3 | CATECHOL1,2-DIOXYGENASE (Burkholderiavietnamiensis) |
PF00775(Dioxygenase_C)PF04444(Dioxygenase_N) | 5 | PRO A 144VAL A 146GLY A 286ALA A 283GLY A 282 | None | 1.12A | 4zjzA-5td3A:undetectable | 4zjzA-5td3A:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ts5 | AMINE OXIDASE (Bothrops atrox) |
PF01593(Amino_oxidase) | 4 | ALA A 455GLY A 473ALA A 48GLY A 45 | None | 0.68A | 4zjzA-5ts5A:undetectable | 4zjzA-5ts5A:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u63 | THIOREDOXINREDUCTASE (Haemophilusinfluenzae) |
PF07992(Pyr_redox_2) | 4 | ALA A 284GLY A 302ALA A 21GLY A 18 | None | 0.65A | 4zjzA-5u63A:undetectable | 4zjzA-5u63A:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5usx | THIOREDOXINREDUCTASE (Vibriovulnificus) |
PF07992(Pyr_redox_2) | 4 | ALA A 284GLY A 302ALA A 21GLY A 18 | None | 0.68A | 4zjzA-5usxA:undetectable | 4zjzA-5usxA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uth | THIOREDOXINREDUCTASE (Mycolicibacteriumsmegmatis) |
PF07992(Pyr_redox_2) | 4 | ALA A 278GLY A 296ALA A 22GLY A 19 | None | 0.63A | 4zjzA-5uthA:undetectable | 4zjzA-5uthA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uxv | SENSORY TRANSDUCTIONREGULATORY PROTEIN (Bartonellaquintana) |
no annotation | 5 | ALA A 190VAL A 215PHE A 217GLY A 200ALA A 203 | None | 1.07A | 4zjzA-5uxvA:4.7 | 4zjzA-5uxvA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5voh | NADH OXIDASE (Lactobacillusbrevis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | ALA A 277GLY A 304ALA A 15GLY A 12 | None | 0.65A | 4zjzA-5vohA:undetectable | 4zjzA-5vohA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w4c | THIOREDOXINREDUCTASE (Cryptococcusneoformans) |
no annotation | 4 | ALA A 314GLY A 332ALA A 45GLY A 42 | None | 0.70A | 4zjzA-5w4cA:undetectable | 4zjzA-5w4cA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x5t | ALPHA-KETOGLUTARICSEMIALDEHYDEDEHYDROGENASE (Azospirillumbrasilense) |
PF00171(Aldedh) | 4 | ALA A 54GLY A 202ALA A 201GLY A 15 | None | 0.68A | 4zjzA-5x5tA:undetectable | 4zjzA-5x5tA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z2g | L-AMINO ACID OXIDASE (Naja atra) |
no annotation | 4 | ALA A 471GLY A 489ALA A 67GLY A 64 | None | 0.70A | 4zjzA-5z2gA:undetectable | 4zjzA-5z2gA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bwt | THIOREDOXINREDUCTASE (Francisellatularensis) |
no annotation | 4 | ALA A 282GLY A 300ALA A 19GLY A 16 | None | 0.66A | 4zjzA-6bwtA:undetectable | 4zjzA-6bwtA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d9y | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Paraburkholderiaphymatum) |
no annotation | 4 | ALA A 162GLY A 147ALA A 146GLY A 150 | None | 0.68A | 4zjzA-6d9yA:undetectable | 4zjzA-6d9yA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f8y | THREONYLCARBAMOYL-AMP SYNTHASE (Pyrococcusabyssi) |
no annotation | 4 | ALA A 141PHE A 31GLY A 40ALA A 41 | THR A 401 (-4.7A)NoneNoneNone | 0.69A | 4zjzA-6f8yA:2.1 | 4zjzA-6f8yA:undetectable |