SIMILAR PATTERNS OF AMINO ACIDS FOR 4ZJ8_A_SUVA2001_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ahi | 7ALPHA-HYDROXYSTEROIDDEHYDROGENASE (Escherichiacoli) |
PF13561(adh_short_C2) | 4 | ILE A 192PRO A 221ILE A 16VAL A 93 | NAI A 302 (-4.1A)NoneNoneNone | 1.00A | 4zj8A-1ahiA:6.1 | 4zj8A-1ahiA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cbk | PROTEIN(7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN-PYROPHOSPHOKINASE) (Haemophilusinfluenzae) |
PF01288(HPPK) | 4 | ILE A 113PRO A 114ILE A 125VAL A 124 | None | 0.72A | 4zj8A-1cbkA:undetectable | 4zj8A-1cbkA:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gji | C-REL PROTO-ONCOGENEPROTEIN (Gallus gallus) |
PF00554(RHD_DNA_bind)PF16179(RHD_dimer) | 4 | TRP A 224PRO A 246ILE A 205VAL A 190 | None | 0.93A | 4zj8A-1gjiA:undetectable | 4zj8A-1gjiA:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ii2 | PHOSPHOENOLPYRUVATECARBOXYKINASE (Trypanosomacruzi) |
PF01293(PEPCK_ATP) | 4 | TRP A 62ILE A 50ILE A 155VAL A 77 | None | 0.93A | 4zj8A-1ii2A:undetectable | 4zj8A-1ii2A:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ksi | COPPER AMINE OXIDASE (Pisum sativum) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3) | 4 | ILE A 31HIS A 39ILE A 41VAL A 21 | None | 0.99A | 4zj8A-1ksiA:undetectable | 4zj8A-1ksiA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q3x | MANNAN-BINDINGLECTIN SERINEPROTEASE 2 (Homo sapiens) |
PF00084(Sushi)PF00089(Trypsin) | 4 | TRP A 678ILE A 533ILE A 497VAL A 460 | None | 0.98A | 4zj8A-1q3xA:undetectable | 4zj8A-1q3xA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qnh | PEPTIDYL-PROLYLCIS-TRANS ISOMERASE (Plasmodiumfalciparum) |
PF00160(Pro_isomerase) | 4 | ILE A 64PRO A 65ILE A 13VAL A 163 | None | 1.01A | 4zj8A-1qnhA:undetectable | 4zj8A-1qnhA:13.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uls | PUTATIVE3-OXOACYL-ACYLCARRIER PROTEINREDUCTASE (Thermusthermophilus) |
PF13561(adh_short_C2) | 4 | ILE A 181PRO A 209ILE A 10VAL A 82 | None | 0.96A | 4zj8A-1ulsA:4.9 | 4zj8A-1ulsA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zjy | R-SPECIFIC ALCOHOLDEHYDROGENASE (Lactobacillusbrevis) |
PF13561(adh_short_C2) | 4 | ILE A 190PRO A 219ILE A 11VAL A 87 | NAI A1270 (-4.6A)NoneNoneNone | 1.01A | 4zj8A-1zjyA:5.3 | 4zj8A-1zjyA:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ac5 | MAPKINASE-INTERACTINGSERINE/THREONINEKINASE 2 (Homo sapiens) |
PF00069(Pkinase) | 4 | TRP A 334ILE A 345ILE A 211VAL A 189 | None | 0.93A | 4zj8A-2ac5A:undetectable | 4zj8A-2ac5A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ayn | UBIQUITINCARBOXYL-TERMINALHYDROLASE 14 (Homo sapiens) |
PF00443(UCH) | 4 | ILE A 169PRO A 171HIS A 179ILE A 151 | None | 0.98A | 4zj8A-2aynA:undetectable | 4zj8A-2aynA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cmt | PEPTIDYL-PROLYLCIS-TRANS ISOMERASEE (Schistosomamansoni) |
PF00160(Pro_isomerase) | 4 | ILE A 64PRO A 65ILE A 19VAL A 163 | None | 0.99A | 4zj8A-2cmtA:undetectable | 4zj8A-2cmtA:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e3u | HYPOTHETICAL PROTEINPH1566 (Pyrococcushorikoshii) |
PF00013(KH_1) | 4 | ILE A 128HIS A 194ILE A 144VAL A 164 | None | 0.99A | 4zj8A-2e3uA:undetectable | 4zj8A-2e3uA:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f6k | METAL-DEPENDENTHYDROLASE (Lactobacillusplantarum) |
PF04909(Amidohydro_2) | 4 | ILE A 203PRO A 204HIS A 9ILE A 53 | NoneNone MN A 402 (-3.5A)None | 0.96A | 4zj8A-2f6kA:undetectable | 4zj8A-2f6kA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fei | CD2-ASSOCIATEDPROTEIN (Homo sapiens) |
PF14604(SH3_9) | 4 | ILE A 11PRO A 12ILE A 26VAL A 6 | None | 0.91A | 4zj8A-2feiA:undetectable | 4zj8A-2feiA:10.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fei | CD2-ASSOCIATEDPROTEIN (Homo sapiens) |
PF14604(SH3_9) | 4 | ILE A 11PRO A 12ILE A 26VAL A 53 | None | 1.01A | 4zj8A-2feiA:undetectable | 4zj8A-2feiA:10.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fzl | DNA REPAIR PROTEINRAD25, XPB (Archaeoglobusfulgidus) |
PF16203(ERCC3_RAD25_C) | 4 | ILE A 418HIS A 376ILE A 408VAL A 410 | None | 0.93A | 4zj8A-2fzlA:3.0 | 4zj8A-2fzlA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hw6 | MAPKINASE-INTERACTINGSERINE/THREONINE-PROTEIN KINASE 1 (Homo sapiens) |
PF00069(Pkinase) | 4 | TRP A 299ILE A 310ILE A 176VAL A 154 | None | 0.97A | 4zj8A-2hw6A:2.3 | 4zj8A-2hw6A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i0s | AROMATIC AMINEDEHYDROGENASE (Alcaligenesfaecalis) |
PF06433(Me-amine-dh_H) | 4 | ILE A 229PRO A 230ILE A 207VAL A 219 | None | 0.96A | 4zj8A-2i0sA:undetectable | 4zj8A-2i0sA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nty | RAC-LIKE GTP-BINDINGPROTEIN ARAC5 (Arabidopsisthaliana) |
PF00071(Ras) | 4 | ILE C 154PRO C 153ILE C 101VAL C 96 | None | 1.00A | 4zj8A-2ntyC:4.4 | 4zj8A-2ntyC:15.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pb9 | PHOSPHOMETHYLPYRIMIDINE KINASE (Pyrococcusfuriosus) |
PF10120(ThiP_synth) | 4 | ILE A 292PRO A 293HIS A 423ILE A 369 | None | 0.98A | 4zj8A-2pb9A:undetectable | 4zj8A-2pb9A:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ph3 | 3-OXOACYL-[ACYLCARRIER PROTEIN]REDUCTASE (Thermusthermophilus) |
PF13561(adh_short_C2) | 4 | ILE A 185PRO A 213ILE A 6VAL A 85 | None | 0.98A | 4zj8A-2ph3A:6.1 | 4zj8A-2ph3A:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2poy | PEPTIDYL-PROLYLCIS-TRANS ISOMERASE (Cryptosporidiumparvum) |
PF00160(Pro_isomerase) | 4 | ILE A 80PRO A 81ILE A 28VAL A 179 | None | 0.97A | 4zj8A-2poyA:undetectable | 4zj8A-2poyA:15.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v26 | MYOSIN VI (Sus scrofa) |
PF00063(Myosin_head) | 4 | ILE A 571HIS A 581ILE A 525VAL A 547 | None | 0.98A | 4zj8A-2v26A:2.1 | 4zj8A-2v26A:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xhc | TRANSCRIPTIONANTITERMINATIONPROTEIN NUSG (Thermotogamaritima) |
PF00467(KOW)PF02357(NusG) | 4 | ILE A 144PRO A 136ILE A 151VAL A 102 | None | 1.00A | 4zj8A-2xhcA:undetectable | 4zj8A-2xhcA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ai2 | NADPH-SORBOSEREDUCTASE (Gluconobacterfrateurii) |
PF13561(adh_short_C2) | 4 | ILE A 190PRO A 230ILE A 12VAL A 90 | NDP A 270 (-4.3A)NoneNoneNone | 1.00A | 4zj8A-3ai2A:6.0 | 4zj8A-3ai2A:18.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ajz | ANCESTRAL CONGERINCON-ANC (-) |
PF00337(Gal-bind_lectin) | 4 | TRP A 66ILE A 39ILE A 85VAL A 17 | GAL A 133 (-3.7A)NoneNoneNone | 0.93A | 4zj8A-3ajzA:undetectable | 4zj8A-3ajzA:15.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3anx | SPERMIDINE SYNTHASE (Thermusthermophilus) |
PF01564(Spermine_synth)PF17284(Spermine_synt_N) | 4 | ILE A 227HIS A 10ILE A 48VAL A 46 | None | 0.91A | 4zj8A-3anxA:undetectable | 4zj8A-3anxA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cgd | PYRIDINENUCLEOTIDE-DISULFIDEOXIDOREDUCTASE,CLASS I (Bacillusanthracis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | ILE A 297PRO A 298ILE A 264VAL A 266 | NoneNAD A 818 (-4.0A)NoneNone | 0.81A | 4zj8A-3cgdA:4.2 | 4zj8A-3cgdA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e9m | OXIDOREDUCTASE,GFO/IDH/MOCA FAMILY (Enterococcusfaecalis) |
PF01408(GFO_IDH_MocA) | 4 | ILE A 71PRO A 72ILE A 281VAL A 284 | None | 0.89A | 4zj8A-3e9mA:7.3 | 4zj8A-3e9mA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f9i | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Rickettsiaprowazekii) |
PF13561(adh_short_C2) | 4 | ILE A 181PRO A 209ILE A 11VAL A 81 | None | 0.95A | 4zj8A-3f9iA:6.0 | 4zj8A-3f9iA:18.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gde | DNA LIGASE (Archaeoglobusfulgidus) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 4 | ILE A 407PRO A 408HIS A 258ILE A 339 | None | 0.85A | 4zj8A-3gdeA:undetectable | 4zj8A-3gdeA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7o | GROUP 3 ALLERGENSMIPP-S YV6023A04 (Sarcoptesscabiei) |
PF00089(Trypsin) | 4 | TRP A 221ILE A 91ILE A 54VAL A 18 | None | 0.82A | 4zj8A-3h7oA:undetectable | 4zj8A-3h7oA:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7o | GROUP 3 ALLERGENSMIPP-S YV6023A04 (Sarcoptesscabiei) |
PF00089(Trypsin) | 4 | TRP A 221ILE A 91ILE A 56VAL A 16 | None | 0.90A | 4zj8A-3h7oA:undetectable | 4zj8A-3h7oA:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3htz | ALANYL-TRNASYNTHETASE (Aquifexaeolicus) |
PF01411(tRNA-synt_2c) | 4 | TRP A 140ILE A 175HIS A 20VAL A 117 | None | 0.86A | 4zj8A-3htzA:3.0 | 4zj8A-3htzA:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ipw | HYDROLASE TATDFAMILY PROTEIN (Entamoebahistolytica) |
PF01026(TatD_DNase) | 4 | PRO A 299HIS A 220ILE A 47VAL A 75 | None | 0.83A | 4zj8A-3ipwA:undetectable | 4zj8A-3ipwA:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | PRE-MRNA-SPLICINGFACTOR SPP42 (Schizosaccharomycespombe) |
PF08082(PRO8NT)PF08083(PROCN)PF10596(U6-snRNA_bdg)PF10597(U5_2-snRNA_bdg)PF10598(RRM_4)PF12134(PRP8_domainIV) | 4 | TRP A1478PRO A 971ILE A1254VAL A1219 | None | 0.94A | 4zj8A-3jb9A:undetectable | 4zj8A-3jb9A:12.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k4h | PUTATIVETRANSCRIPTIONALREGULATOR (Bacilluscytotoxicus) |
PF13377(Peripla_BP_3) | 4 | ILE A 134HIS A 171ILE A 203VAL A 207 | None | 0.90A | 4zj8A-3k4hA:5.9 | 4zj8A-3k4hA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kom | TRANSKETOLASE (Francisellatularensis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | ILE A 5HIS A 234ILE A 243VAL A 218 | None | 0.94A | 4zj8A-3komA:undetectable | 4zj8A-3komA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pym | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE3 (Saccharomycescerevisiae) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ILE A 72HIS A 109ILE A 92VAL A 2 | None | 1.01A | 4zj8A-3pymA:7.3 | 4zj8A-3pymA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r1o | ODORANT BINDINGPROTEIN, ANTENNAL (Anophelesgambiae) |
PF01395(PBP_GOBP) | 4 | ILE A 118HIS A 18ILE A 50VAL A 107 | NoneNonePLM A 128 ( 4.9A)PLM A 128 ( 4.7A) | 0.96A | 4zj8A-3r1oA:undetectable | 4zj8A-3r1oA:13.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s9b | VIPERA RUSSELLIPROTEINASE RVV-VGAMMA (Daboiasiamensis) |
PF00089(Trypsin) | 4 | TRP A 237ILE A 103ILE A 66VAL A 31 | None | 0.99A | 4zj8A-3s9bA:undetectable | 4zj8A-3s9bA:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tju | GRANZYME H (Homo sapiens) |
PF00089(Trypsin) | 4 | TRP A 233ILE A 104ILE A 65VAL A 33 | None | 0.86A | 4zj8A-3tjuA:undetectable | 4zj8A-3tjuA:17.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zw1 | BAMBL LECTIN (Burkholderiaambifaria) |
PF07938(Fungal_lectin) | 4 | TRP A 34ILE A 14ILE A 24VAL A 46 | None | 0.94A | 4zj8A-3zw1A:undetectable | 4zj8A-3zw1A:10.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4anj | UNCONVENTIONALMYOSIN-VI, GREENFLUORESCENT PROTEIN (Aequoreavictoria;Sus scrofa) |
PF00063(Myosin_head)PF01353(GFP) | 4 | ILE A 571HIS A 581ILE A 525VAL A 547 | None | 1.00A | 4zj8A-4anjA:3.6 | 4zj8A-4anjA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bzg | ALDOSE 1-EPIMERASE (Bacillussubtilis) |
PF01263(Aldose_epim) | 5 | ILE A 66PRO A 67HIS A 106ILE A 127VAL A 145 | None | 1.49A | 4zj8A-4bzgA:undetectable | 4zj8A-4bzgA:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cp8 | ALLOPHANATEHYDROLASE (Pseudomonas sp.ADP) |
PF01425(Amidase) | 4 | ILE A 192PRO A 193ILE A 151VAL A 397 | None | 0.85A | 4zj8A-4cp8A:undetectable | 4zj8A-4cp8A:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4csd | FUCOSE-BINDINGLECTIN PROTEIN (Ralstoniasolanacearum) |
PF07938(Fungal_lectin) | 4 | TRP A 36ILE A 16ILE A 26VAL A 48 | MFU A 304 (-3.9A)NoneNoneNone | 0.93A | 4zj8A-4csdA:undetectable | 4zj8A-4csdA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4csd | FUCOSE-BINDINGLECTIN PROTEIN (Ralstoniasolanacearum) |
PF07938(Fungal_lectin) | 4 | TRP A 127ILE A 107ILE A 117VAL A 139 | MFU A 306 (-3.9A)NoneNoneNone | 0.91A | 4zj8A-4csdA:undetectable | 4zj8A-4csdA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4csd | FUCOSE-BINDINGLECTIN PROTEIN (Ralstoniasolanacearum) |
PF07938(Fungal_lectin) | 4 | TRP A 218ILE A 198ILE A 208VAL A 230 | MFU A 302 (-4.0A)NoneNoneNone | 0.94A | 4zj8A-4csdA:undetectable | 4zj8A-4csdA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e7n | SNAKE-VENOMTHROMBIN-LIKE ENZYME (Gloydius halys) |
PF00089(Trypsin) | 4 | TRP A 237ILE A 103ILE A 66VAL A 31 | None | 0.95A | 4zj8A-4e7nA:undetectable | 4zj8A-4e7nA:15.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eyv | PEPTIDYL-PROLYLCIS-TRANS ISOMERASE (Serendipitaindica) |
PF00160(Pro_isomerase) | 4 | ILE A 57PRO A 58ILE A 12VAL A 156 | None | 0.94A | 4zj8A-4eyvA:undetectable | 4zj8A-4eyvA:13.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fn5 | ELONGATION FACTOR G1 (Pseudomonasaeruginosa) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF03144(GTP_EFTU_D2)PF03764(EFG_IV)PF14492(EFG_II) | 4 | TRP A 193PRO A 276ILE A 15VAL A 110 | None | 1.00A | 4zj8A-4fn5A:5.5 | 4zj8A-4fn5A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fxg | MANNAN-BINDINGLECTIN SERINEPROTEASE 2 B CHAIN (Homo sapiens) |
PF00089(Trypsin) | 4 | TRP H 678ILE H 533ILE H 497VAL H 460 | None | 1.00A | 4zj8A-4fxgH:undetectable | 4zj8A-4fxgH:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h16 | SHORT CHAIN ALCOHOLDEHYDROGENASE-RELATED DEHYDROGENASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 4 | ILE A 184PRO A 226ILE A 14VAL A 81 | None | 1.01A | 4zj8A-4h16A:2.5 | 4zj8A-4h16A:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l22 | PHOSPHORYLASE (Streptococcusmutans) |
PF00343(Phosphorylase) | 4 | ILE A 319HIS A 369ILE A 375VAL A 381 | None | 0.89A | 4zj8A-4l22A:18.5 | 4zj8A-4l22A:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mbo | SERINE-RICH REPEATADHESIONGLYCOPROTEIN (SRR1) (Streptococcusagalactiae) |
PF10425(SdrG_C_C) | 4 | ILE A 382HIS A 409ILE A 440VAL A 465 | None | 0.87A | 4zj8A-4mboA:undetectable | 4zj8A-4mboA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mpt | PUTATIVELEU/ILE/VAL-BINDINGPROTEIN (Bordetellapertussis) |
PF13458(Peripla_BP_6) | 4 | ILE A 103PRO A 102ILE A 64VAL A 88 | None | 1.01A | 4zj8A-4mptA:5.3 | 4zj8A-4mptA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mv3 | BIOTIN CARBOXYLASE (Haemophilusinfluenzae) |
PF00289(Biotin_carb_N)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | ILE A 158HIS A 236ILE A 287VAL A 131 | NoneACP A 501 ( 3.9A)ACP A 501 ( 4.3A)ACP A 501 ( 4.5A) | 1.01A | 4zj8A-4mv3A:undetectable | 4zj8A-4mv3A:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nbr | HYPOTHETICAL3-OXOACYL-(ACYL-CARRIER PROTEIN)REDUCTASE (Brucellaabortus) |
PF13561(adh_short_C2) | 4 | ILE A 205PRO A 233ILE A 24VAL A 99 | None | 0.93A | 4zj8A-4nbrA:5.6 | 4zj8A-4nbrA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nbt | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Acholeplasmalaidlawii) |
PF13561(adh_short_C2) | 4 | ILE A 181PRO A 209ILE A 11VAL A 79 | NAD A 301 (-4.4A)NoneNoneNone | 0.96A | 4zj8A-4nbtA:5.4 | 4zj8A-4nbtA:17.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nbw | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Plesiocystispacifica) |
PF13561(adh_short_C2) | 4 | ILE A 203PRO A 231ILE A 17VAL A 94 | NAD A 301 (-4.2A)NoneNoneNone | 0.99A | 4zj8A-4nbwA:5.5 | 4zj8A-4nbwA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o8m | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Actinobacillussuccinogenes) |
PF03480(DctP) | 4 | TRP A 125ILE A 105ILE A 138VAL A 240 | None | 0.91A | 4zj8A-4o8mA:undetectable | 4zj8A-4o8mA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p9a | POLYMERASE PA (Influenza Avirus) |
PF00603(Flu_PA) | 4 | TRP A 317ILE A 545ILE A 505VAL A 521 | None | 0.95A | 4zj8A-4p9aA:undetectable | 4zj8A-4p9aA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q73 | PROLINEDEHYDROGENASE (Bradyrhizobiumdiazoefficiens) |
PF00171(Aldedh)PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 4 | ILE A 663PRO A 656ILE A 741VAL A 729 | None | 0.95A | 4zj8A-4q73A:3.6 | 4zj8A-4q73A:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qiw | DNA-DIRECTED RNAPOLYMERASE (Thermococcuskodakarensis) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 4 | ILE A 332HIS A 507ILE A 501VAL A 487 | None | 1.01A | 4zj8A-4qiwA:5.1 | 4zj8A-4qiwA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qlz | SJCHGC07024 PROTEIN (Schistosomajaponicum) |
PF00719(Pyrophosphatase) | 4 | ILE A 126PRO A 48HIS A 68ILE A 277 | None | 1.01A | 4zj8A-4qlzA:undetectable | 4zj8A-4qlzA:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r1n | 3-HYDROXYBUTYRYL-COADEHYDROGENASE (Clostridiumbutyricum) |
PF00725(3HCDH)PF02737(3HCDH_N) | 4 | ILE A 89HIS A 138ILE A 16VAL A 6 | None | 1.00A | 4zj8A-4r1nA:4.9 | 4zj8A-4r1nA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rnc | ESTERASE (Rhodococcus sp.ECU1013) |
PF12697(Abhydrolase_6) | 4 | ILE A 107HIS A 62ILE A 14VAL A 85 | None | 0.96A | 4zj8A-4rncA:undetectable | 4zj8A-4rncA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rpc | PUTATIVE ALPHA/BETAHYDROLASE (Desulfitobacteriumhafniense) |
PF12697(Abhydrolase_6) | 4 | ILE A 50PRO A 51ILE A 108VAL A 83 | None | 0.98A | 4zj8A-4rpcA:3.3 | 4zj8A-4rpcA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rvp | SUPEROXIDE DISMUTASE (Sedum alfredii) |
PF00080(Sod_Cu) | 4 | PRO A 54HIS A 58ILE A 111VAL A 109 | None | 0.98A | 4zj8A-4rvpA:undetectable | 4zj8A-4rvpA:14.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4s0v | HUMAN OREXINRECEPTOR TYPE 2FUSION PROTEIN TO P.ABYSII GLYCOGENSYNTHASE (Homo sapiens;Pyrococcusabyssi) |
PF00001(7tm_1)PF00534(Glycos_transf_1) | 6 | TRP A 120ILE A 130PRO A 131HIS A 224ILE A 320VAL A 353 | NoneSUV A2001 (-4.8A)SUV A2001 (-4.0A)SUV A2001 ( 4.8A)SUV A2001 (-4.1A)SUV A2001 ( 4.9A) | 0.38A | 4zj8A-4s0vA:46.2 | 4zj8A-4s0vA:83.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s12 | N-ACETYLMURAMIC ACID6-PHOSPHATE ETHERASE (Yersiniaenterocolitica) |
PF01380(SIS) | 4 | ILE A 172PRO A 171ILE A 7VAL A 183 | None | 1.01A | 4zj8A-4s12A:undetectable | 4zj8A-4s12A:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wd9 | NISIN BIOSYNTHESISPROTEIN NISB (Lactococcuslactis) |
PF04738(Lant_dehydr_N)PF14028(Lant_dehydr_C) | 4 | ILE A 224HIS A 511ILE A 514VAL A 519 | None | 1.00A | 4zj8A-4wd9A:undetectable | 4zj8A-4wd9A:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x1v | CD2-ASSOCIATEDPROTEIN (Homo sapiens) |
PF14604(SH3_9) | 4 | ILE A 120PRO A 121ILE A 135VAL A 115 | None | 0.97A | 4zj8A-4x1vA:undetectable | 4zj8A-4x1vA:8.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x8n | SET1/ASH2 HISTONEMETHYLTRANSFERASECOMPLEX SUBUNIT ASH2 (Homo sapiens) |
PF00622(SPRY) | 4 | PRO A 470HIS A 292ILE A 300VAL A 307 | None | 0.97A | 4zj8A-4x8nA:undetectable | 4zj8A-4x8nA:15.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xsr | ALR3699 PROTEIN (Nostoc sp. PCC7120) |
no annotation | 4 | PRO B 327HIS B 205ILE B 294VAL B 316 | None | 0.98A | 4zj8A-4xsrB:9.9 | 4zj8A-4xsrB:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z38 | MLNA (Bacillusvelezensis) |
no annotation | 4 | ILE A 481PRO A 478HIS A 542ILE A 502 | None | 0.91A | 4zj8A-4z38A:undetectable | 4zj8A-4z38A:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zlr | BRAIN TUMOR PROTEIN (Drosophilamelanogaster) |
PF01436(NHL) | 4 | ILE A 984HIS A 977ILE A 961VAL A1007 | NoneSO4 A1103 (-3.9A) U C 4 ( 4.6A)None | 0.92A | 4zj8A-4zlrA:undetectable | 4zj8A-4zlrA:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxc | HYDROQUINONEDIOXYGENASE LARGESUBUNITHYDROQUINONEDIOXYGENASE SMALLSUBUNIT (Pseudomonas sp.WBC-3) |
no annotation | 4 | ILE W 337PRO W 336ILE W 287VAL A 21 | None | 0.99A | 4zj8A-4zxcW:undetectable | 4zj8A-4zxcW:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cad | SM80.1 VICILIN (Solanummelongena) |
PF00190(Cupin_1) | 4 | ILE A 72HIS A 65ILE A 84VAL A 208 | NonePCA A 403 (-3.9A)NoneNone | 0.79A | 4zj8A-5cadA:undetectable | 4zj8A-5cadA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cb0 | UNIVERSAL STRESSPROTEIN E (Escherichiacoli) |
PF00582(Usp) | 4 | TRP A 150ILE A 265HIS A 244ILE A 238 | Z6X A 401 (-4.0A)Z6X A 401 ( 4.1A)NoneNone | 0.97A | 4zj8A-5cb0A:undetectable | 4zj8A-5cb0A:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cvv | (ISO)EUGENOLO-METHYLTRANSFERASE (Clarkia breweri) |
PF00891(Methyltransf_2)PF08100(Dimerisation) | 4 | ILE A 155HIS A 237ILE A 175VAL A 138 | None | 0.97A | 4zj8A-5cvvA:undetectable | 4zj8A-5cvvA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5djs | TETRATRICOPEPTIDETPR_2 REPEAT PROTEIN (Thermobaculumterrenum) |
PF13181(TPR_8)PF13844(Glyco_transf_41) | 4 | TRP A 246ILE A 271ILE A 97VAL A 93 | None | 0.89A | 4zj8A-5djsA:14.6 | 4zj8A-5djsA:23.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ip9 | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB1 (Saccharomycescerevisiae) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04990(RNA_pol_Rpb1_7)PF04992(RNA_pol_Rpb1_6)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 4 | ILE A 586PRO A 583ILE A 531VAL A 617 | None | 1.01A | 4zj8A-5ip9A:5.8 | 4zj8A-5ip9A:14.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kf7 | BIFUNCTIONAL PROTEINPUTA (Sinorhizobiummeliloti) |
PF00171(Aldedh)PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 4 | ILE A 712PRO A 705ILE A 790VAL A 778 | NoneNAD A2002 (-4.3A)NoneNone | 1.01A | 4zj8A-5kf7A:undetectable | 4zj8A-5kf7A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kf7 | BIFUNCTIONAL PROTEINPUTA (Sinorhizobiummeliloti) |
PF00171(Aldedh)PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 4 | ILE A 929HIS A 869ILE A 833VAL A 832 | None | 1.01A | 4zj8A-5kf7A:undetectable | 4zj8A-5kf7A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kh0 | SMALL GTP-BINDINGPROTEIN (Thermosiphomelanesiensis) |
PF01926(MMR_HSR1) | 4 | ILE A 98PRO A 99ILE A 94VAL A 19 | None | 0.86A | 4zj8A-5kh0A:2.1 | 4zj8A-5kh0A:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n5p | PUTATIVECELLULOSOMALSCAFFOLDIN PROTEIN (Ruminococcusflavefaciens) |
no annotation | 4 | TRP A 748ILE A 853ILE B 717VAL B 720 | None | 0.94A | 4zj8A-5n5pA:undetectable | 4zj8A-5n5pA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nd5 | TRANSKETOLASE (Chlamydomonasreinhardtii) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | ILE A 59PRO A 86ILE A 282VAL A 95 | None | 0.94A | 4zj8A-5nd5A:undetectable | 4zj8A-5nd5A:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oms | CYTOCHROME P450 (Amycolatopsissp. ATCC 39116) |
no annotation | 4 | ILE A 278PRO A 279ILE A 108VAL A 112 | None | 0.99A | 4zj8A-5omsA:undetectable | 4zj8A-5omsA:8.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wpi | HSVA (Erwiniaamylovora) |
no annotation | 4 | TRP A 279PRO A 256ILE A 128VAL A 20 | TRP A 279 ( 0.5A)PRO A 256 ( 1.1A)ILE A 128 ( 0.7A)VAL A 20 ( 0.6A) | 0.94A | 4zj8A-5wpiA:undetectable | 4zj8A-5wpiA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wug | BETA-GLUCOSIDASE (Paenibacillusbarengoltzii) |
no annotation | 4 | PRO A 301HIS A 260ILE A 214VAL A 226 | None | 0.97A | 4zj8A-5wugA:3.4 | 4zj8A-5wugA:11.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xdr | PRE-MRNA-SPLICINGFACTOR ATP-DEPENDENTRNA HELICASE DHX15 (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF04408(HA2)PF07717(OB_NTP_bind) | 4 | ILE A 386PRO A 387ILE A 336VAL A 339 | None | 0.87A | 4zj8A-5xdrA:2.4 | 4zj8A-5xdrA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zvs | VP2 (Aquareovirus C) |
no annotation | 4 | TRP 2 875ILE 2 909HIS 2 932ILE 2 918 | None | 0.95A | 4zj8A-5zvs2:undetectable | 4zj8A-5zvs2:10.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bnp | UNCONVENTIONALMYOSIN-VI (Sus scrofa) |
no annotation | 4 | ILE I 571HIS I 581ILE I 525VAL I 547 | None | 0.93A | 4zj8A-6bnpI:undetectable | 4zj8A-6bnpI:9.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ejb | XYLOSYLTRANSFERASE 1 (Homo sapiens) |
no annotation | 4 | TRP A 555HIS A 335ILE A 568VAL A 569 | None | 0.87A | 4zj8A-6ejbA:4.5 | 4zj8A-6ejbA:8.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fd2 | PUTATIVE APRAMYCINBIOSYNTHETICOXIDOREDUCTASE 4 (Streptoalloteichustenebrarius) |
no annotation | 4 | ILE B 200HIS B 83ILE B 62VAL B 182 | None | 0.85A | 4zj8A-6fd2B:undetectable | 4zj8A-6fd2B:12.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g9o | VOLUME-REGULATEDANION CHANNELSUBUNIT LRRC8A (Mus musculus) |
no annotation | 4 | ILE A 500HIS A 431ILE A 456VAL A 459 | None | 0.92A | 4zj8A-6g9oA:3.4 | 4zj8A-6g9oA:8.43 |