SIMILAR PATTERNS OF AMINO ACIDS FOR 4ZE3_A_TPFA602_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a2o CHEB METHYLESTERASE

(Salmonella
enterica)
PF00072
(Response_reg)
PF01339
(CheB_methylest)
4 PHE A 199
GLY A 167
THR A 281
LEU A 330
None
0.84A 4ze3A-1a2oA:
0.0
4ze3A-1a2oA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c30 CARBAMOYL PHOSPHATE
SYNTHETASE: LARGE
SUBUNIT


(Escherichia
coli)
PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3)
4 PHE A 928
GLY A1046
THR A1043
LEU A 907
None
None
ORN  A4010 ( 4.9A)
ORN  A4010 (-4.0A)
0.85A 4ze3A-1c30A:
0.0
4ze3A-1c30A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1chd CHEB METHYLESTERASE

(Salmonella
enterica)
PF01339
(CheB_methylest)
4 PHE A 199
GLY A 167
THR A 281
LEU A 330
None
0.84A 4ze3A-1chdA:
undetectable
4ze3A-1chdA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dfx DESULFOFERRODOXIN

(Desulfovibrio
desulfuricans)
PF01880
(Desulfoferrodox)
PF06397
(Desulfoferrod_N)
4 TYR A   7
ILE A  15
GLY A 119
THR A  41
None
0.85A 4ze3A-1dfxA:
undetectable
4ze3A-1dfxA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ej6 LAMBDA1

(Reovirus sp.)
no annotation 4 PHE B 831
ILE B 522
PHE B 733
LEU B 864
None
0.80A 4ze3A-1ej6B:
0.7
4ze3A-1ej6B:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kho ALPHA-TOXIN

(Clostridium
perfringens)
PF00882
(Zn_dep_PLPC)
PF01477
(PLAT)
4 PHE A 192
ILE A 179
PHE A 196
GLY A 231
None
0.88A 4ze3A-1khoA:
1.8
4ze3A-1khoA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l0q SURFACE LAYER
PROTEIN


(Methanosarcina
mazei)
PF00801
(PKD)
PF10282
(Lactonase)
4 PHE A 294
ILE A   6
GLY A 248
THR A 217
None
0.89A 4ze3A-1l0qA:
undetectable
4ze3A-1l0qA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1llc L-LACTATE
DEHYDROGENASE


(Lactobacillus
casei)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 ILE A 281
PHE A 200
GLY A 193
THR A 165
None
0.92A 4ze3A-1llcA:
undetectable
4ze3A-1llcA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oa1 HYDROXYLAMINE
REDUCTASE


(Desulfovibrio
vulgaris)
PF03063
(Prismane)
4 PHE A  61
ILE A  41
GLY A  65
THR A  69
None
0.88A 4ze3A-1oa1A:
undetectable
4ze3A-1oa1A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rf5 5-ENOLPYRUVYLSHIKIMA
TE-3-PHOSPHATE
SYNTHASE


(Streptococcus
pneumoniae)
PF00275
(EPSP_synthase)
5 PHE A 238
ILE A 316
PHE A 417
GLY A 387
LEU A   3
None
1.47A 4ze3A-1rf5A:
undetectable
4ze3A-1rf5A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tdt TETRAHYDRODIPICOLINA
TE-N-SUCCINYLTRANSFE
RASE


(Mycobacterium
bovis)
PF00132
(Hexapep)
PF14602
(Hexapep_2)
PF14805
(THDPS_N_2)
4 ILE A 177
GLY A 153
THR A 138
LEU A 158
None
0.89A 4ze3A-1tdtA:
undetectable
4ze3A-1tdtA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ud9 DNA POLYMERASE
SLIDING CLAMP A


(Sulfurisphaera
tokodaii)
PF00705
(PCNA_N)
PF02747
(PCNA_C)
4 TYR A   5
PHE A  27
ILE A  34
LEU A 210
None
0.91A 4ze3A-1ud9A:
undetectable
4ze3A-1ud9A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1urj MAJOR DNA-BINDING
PROTEIN


(Human
alphaherpesvirus
1)
PF00747
(Viral_DNA_bp)
4 PHE A  97
GLY A 141
THR A 139
LEU A 176
None
0.87A 4ze3A-1urjA:
undetectable
4ze3A-1urjA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wom SIGMA FACTOR SIGB
REGULATION PROTEIN
RSBQ


(Bacillus
subtilis)
PF12697
(Abhydrolase_6)
4 PHE A  41
ILE A  21
GLY A 262
LEU A 214
None
0.78A 4ze3A-1womA:
undetectable
4ze3A-1womA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x8v CYTOCHROME P450 51

(Mycobacterium
tuberculosis)
PF00067
(p450)
4 TYR A  76
PHE A  83
THR A 260
LEU A 321
ESL  A 471 ( 3.8A)
None
HEM  A 470 (-3.6A)
HEM  A 470 (-4.1A)
0.93A 4ze3A-1x8vA:
35.3
4ze3A-1x8vA:
28.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2epk N-ACETYL-BETA-D-GLUC
OSAMINIDASE


(Streptococcus
gordonii)
PF00728
(Glyco_hydro_20)
4 ILE X 618
GLY X 342
THR X 344
LEU X 495
None
0.89A 4ze3A-2epkX:
undetectable
4ze3A-2epkX:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fna CONSERVED
HYPOTHETICAL PROTEIN


(Sulfolobus
solfataricus)
PF01637
(ATPase_2)
4 ILE A  45
PHE A 208
THR A 246
LEU A   2
None
None
ADP  A 500 (-3.5A)
ADP  A 500 ( 4.9A)
0.93A 4ze3A-2fnaA:
1.4
4ze3A-2fnaA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iqi HYPOTHETICAL PROTEIN
XCC0632


(Xanthomonas
campestris)
PF03886
(ABC_trans_aux)
4 TYR A 123
PHE A 103
ILE A 109
GLY A 197
None
0.92A 4ze3A-2iqiA:
undetectable
4ze3A-2iqiA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o7r CXE CARBOXYLESTERASE

(Actinidia
eriantha)
PF07859
(Abhydrolase_3)
4 PHE A 104
ILE A 103
GLY A  92
LEU A 222
None
None
4PA  A 369 (-3.5A)
None
0.76A 4ze3A-2o7rA:
undetectable
4ze3A-2o7rA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ozj CUPIN 2, CONSERVED
BARREL


(Desulfitobacterium
hafniense)
no annotation 4 TYR A  61
ILE A  63
PHE A  44
GLY A  97
None
0.81A 4ze3A-2ozjA:
undetectable
4ze3A-2ozjA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2reb REC A

(Escherichia
coli)
PF00154
(RecA)
4 TYR A  65
ILE A 192
GLY A  71
THR A 242
None
0.85A 4ze3A-2rebA:
undetectable
4ze3A-2rebA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rfo NUCLEOPORIN NIC96

(Saccharomyces
cerevisiae)
PF04097
(Nic96)
4 TYR A 556
PHE A 534
ILE A 537
GLY A 509
None
0.87A 4ze3A-2rfoA:
undetectable
4ze3A-2rfoA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wed PENICILLOPEPSIN

(Penicillium
janthinellum)
PF00026
(Asp)
4 ILE A 260
PHE A 208
GLY A 210
LEU A 219
None
0.90A 4ze3A-2wedA:
undetectable
4ze3A-2wedA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2whk MANNAN
ENDO-1,4-BETA-MANNOS
IDASE


(Bacillus
subtilis)
PF02156
(Glyco_hydro_26)
5 PHE A 243
ILE A 249
PHE A 276
GLY A 268
LEU A 313
None
1.38A 4ze3A-2whkA:
undetectable
4ze3A-2whkA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wlc POLYSIALIC ACID
O-ACETYLTRANSFERASE


(Neisseria
meningitidis)
PF00132
(Hexapep)
4 ILE A 139
GLY A 104
THR A  86
LEU A 109
None
EDO  A1218 (-3.5A)
None
None
0.79A 4ze3A-2wlcA:
undetectable
4ze3A-2wlcA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a21 PUTATIVE SECRETED
ALPHA-GALACTOSIDASE


(Streptomyces
avermitilis)
PF00652
(Ricin_B_lectin)
PF16499
(Melibiase_2)
4 TYR A 357
ILE A 381
GLY A 421
LEU A 261
None
GOL  A 915 (-4.7A)
None
None
0.87A 4ze3A-3a21A:
undetectable
4ze3A-3a21A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8e YGHU, GLUTATHIONE
S-TRANSFERASE
HOMOLOGUE


(Escherichia
coli)
PF02798
(GST_N)
PF13410
(GST_C_2)
4 ILE A  82
GLY A  55
THR A  59
LEU A  47
GSH  A 289 (-3.7A)
None
None
None
0.92A 4ze3A-3c8eA:
undetectable
4ze3A-3c8eA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmt PROTEIN RECA

(Escherichia
coli)
PF00154
(RecA)
4 TYR A  65
ILE A 192
GLY A  71
THR A 242
None
None
ADP  A 502 (-3.3A)
None
0.89A 4ze3A-3cmtA:
undetectable
4ze3A-3cmtA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmt PROTEIN RECA

(Escherichia
coli)
PF00154
(RecA)
4 TYR A1065
ILE A1192
GLY A1071
THR A1242
None
None
ADP  A1502 (-3.4A)
None
0.90A 4ze3A-3cmtA:
undetectable
4ze3A-3cmtA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmt PROTEIN RECA

(Escherichia
coli)
PF00154
(RecA)
4 TYR A2065
ILE A2192
GLY A2071
THR A2242
None
None
ADP  A2502 (-3.4A)
None
0.90A 4ze3A-3cmtA:
undetectable
4ze3A-3cmtA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmt PROTEIN RECA

(Escherichia
coli)
PF00154
(RecA)
4 TYR A3065
ILE A3192
GLY A3071
THR A3242
None
None
ADP  A3502 (-3.4A)
None
0.89A 4ze3A-3cmtA:
undetectable
4ze3A-3cmtA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmt PROTEIN RECA

(Escherichia
coli)
PF00154
(RecA)
4 TYR A4065
ILE A4192
GLY A4071
THR A4242
None
None
ADP  A4502 (-3.2A)
None
0.90A 4ze3A-3cmtA:
undetectable
4ze3A-3cmtA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmv PROTEIN RECA

(Escherichia
coli)
PF00154
(RecA)
4 TYR A1065
ILE A1192
GLY A1071
THR A1242
None
None
ANP  A1400 (-3.1A)
None
0.89A 4ze3A-3cmvA:
undetectable
4ze3A-3cmvA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmv PROTEIN RECA

(Escherichia
coli)
PF00154
(RecA)
4 TYR A2065
ILE A2192
GLY A2071
THR A2242
None
None
ANP  A2400 (-3.7A)
None
0.92A 4ze3A-3cmvA:
undetectable
4ze3A-3cmvA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d8b FIDGETIN-LIKE
PROTEIN 1


(Homo sapiens)
PF00004
(AAA)
PF09336
(Vps4_C)
4 PHE A 486
ILE A 539
PHE A 524
LEU A 559
None
0.83A 4ze3A-3d8bA:
undetectable
4ze3A-3d8bA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dy5 ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN


(Plexaura
homomalla)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
4 TYR A 171
ILE A 143
GLY A 139
LEU A 292
None
0.78A 4ze3A-3dy5A:
2.1
4ze3A-3dy5A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ewn THIJ/PFPI FAMILY
PROTEIN


(Pseudomonas
syringae group
genomosp. 3)
PF01965
(DJ-1_PfpI)
4 PHE A  76
ILE A  56
PHE A 211
LEU A 160
None
0.86A 4ze3A-3ewnA:
undetectable
4ze3A-3ewnA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fmb DIMERIC PROTEIN OF
UNKNOWN FUNCTION AND
FERREDOXIN-LIKE FOLD


(Bacteroides
fragilis)
PF07876
(Dabb)
4 PHE A   8
ILE A  57
GLY A  82
LEU A  33
None
0.73A 4ze3A-3fmbA:
undetectable
4ze3A-3fmbA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g0o 3-HYDROXYISOBUTYRATE
DEHYDROGENASE


(Salmonella
enterica)
PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11)
4 PHE A  60
GLY A  10
THR A  32
LEU A  45
None
0.92A 4ze3A-3g0oA:
undetectable
4ze3A-3g0oA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hd6 AMMONIUM TRANSPORTER
RH TYPE C


(Homo sapiens)
PF00909
(Ammonium_transp)
4 TYR A 241
GLY A 180
THR A 183
LEU A 170
None
0.92A 4ze3A-3hd6A:
undetectable
4ze3A-3hd6A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hfw PROTEIN
ADP-RIBOSYLARGININE
HYDROLASE


(Homo sapiens)
PF03747
(ADP_ribosyl_GH)
4 TYR A 279
ILE A 309
GLY A 171
LEU A 195
None
0.91A 4ze3A-3hfwA:
undetectable
4ze3A-3hfwA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrd NICOTINATE
DEHYDROGENASE
FAD-SUBUNIT


(Eubacterium
barkeri)
PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C)
4 PHE C  77
ILE C  80
GLY C 112
LEU C 148
FAD  C 900 (-4.2A)
None
FAD  C 900 ( 4.3A)
None
0.87A 4ze3A-3hrdC:
undetectable
4ze3A-3hrdC:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9v NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 1


(Thermus
thermophilus)
PF01512
(Complex1_51K)
PF10531
(SLBB)
PF10589
(NADH_4Fe-4S)
4 ILE 1 149
PHE 1 169
GLY 1 130
LEU 1 224
None
0.85A 4ze3A-3i9v1:
undetectable
4ze3A-3i9v1:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iz3 VIRAL STRUCTURAL
PROTEIN 5


(Cypovirus 1)
no annotation 4 PHE D  31
ILE D  19
PHE D 179
THR D 233
None
0.77A 4ze3A-3iz3D:
undetectable
4ze3A-3iz3D:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jaz VIRAL STRUCTURAL
PROTEIN 5


(Cypovirus 1)
no annotation 4 PHE D  31
ILE D  19
PHE D 179
THR D 233
None
0.92A 4ze3A-3jazD:
undetectable
4ze3A-3jazD:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jr3 NAD-DEPENDENT
DEACETYLASE


(Thermotoga
maritima)
PF02146
(SIR2)
4 ILE A 245
PHE A   6
THR A  18
LEU A 187
None
0.90A 4ze3A-3jr3A:
undetectable
4ze3A-3jr3A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kt4 PKHD-TYPE
HYDROXYLASE TPA1


(Saccharomyces
cerevisiae)
PF10637
(Ofd1_CTDD)
PF13661
(2OG-FeII_Oxy_4)
4 PHE A 129
ILE A 168
GLY A  56
LEU A 189
None
0.93A 4ze3A-3kt4A:
undetectable
4ze3A-3kt4A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l8k DIHYDROLIPOYL
DEHYDROGENASE


(Sulfolobus
solfataricus)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 PHE A 189
ILE A 185
PHE A  74
THR A 164
None
0.88A 4ze3A-3l8kA:
undetectable
4ze3A-3l8kA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpp SUCRASE-ISOMALTASE

(Homo sapiens)
PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N)
4 PHE A 589
ILE A 594
GLY A 243
THR A 229
None
0.83A 4ze3A-3lppA:
undetectable
4ze3A-3lppA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m3p GLUTAMINE AMIDO
TRANSFERASE


(Methylobacillus
flagellatus)
PF00117
(GATase)
4 PHE A 144
ILE A 146
GLY A 172
LEU A 128
None
0.91A 4ze3A-3m3pA:
undetectable
4ze3A-3m3pA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1


(Bifidobacterium
longum)
PF01547
(SBP_bac_1)
4 PHE A 486
ILE A 485
PHE A 220
GLY A 246
None
0.87A 4ze3A-3ombA:
undetectable
4ze3A-3ombA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3onq REGULATOR OF
POLYKETIDE SYNTHASE
EXPRESSION


(Bifidobacterium
adolescentis)
PF13556
(HTH_30)
4 ILE A  71
GLY A  57
THR A 140
LEU A 137
None
0.80A 4ze3A-3onqA:
undetectable
4ze3A-3onqA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qfk UNCHARACTERIZED
PROTEIN


(Staphylococcus
aureus)
PF00149
(Metallophos)
PF02872
(5_nucleotid_C)
4 PHE A  88
ILE A  52
PHE A 134
LEU A 260
None
0.81A 4ze3A-3qfkA:
undetectable
4ze3A-3qfkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tk8 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-SUCCINYLTRANSFERAS
E


(Burkholderia
pseudomallei)
PF00132
(Hexapep)
PF14602
(Hexapep_2)
PF14805
(THDPS_N_2)
4 ILE A 216
GLY A 192
THR A 177
LEU A 197
None
0.88A 4ze3A-3tk8A:
undetectable
4ze3A-3tk8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE


(Sinorhizobium
meliloti)
PF13561
(adh_short_C2)
4 ILE A  92
GLY A 117
THR A 121
LEU A  35
None
0.93A 4ze3A-3v8bA:
undetectable
4ze3A-3v8bA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x0v L-LYSINE OXIDASE

(Trichoderma
viride)
PF01593
(Amino_oxidase)
4 TYR A  92
ILE A  90
GLY A 230
THR A  51
None
0.87A 4ze3A-3x0vA:
undetectable
4ze3A-3x0vA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4awe ENDO-BETA-D-1,4-MANN
ANASE


(Neurospora
sitophila)
PF00150
(Cellulase)
4 PHE A  54
ILE A 115
PHE A 346
GLY A  42
None
0.89A 4ze3A-4aweA:
undetectable
4ze3A-4aweA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4db1 MYOSIN-7

(Homo sapiens)
PF00063
(Myosin_head)
PF02736
(Myosin_N)
4 PHE A 312
ILE A 356
GLY A 425
LEU A 399
None
0.81A 4ze3A-4db1A:
undetectable
4ze3A-4db1A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4djt GTP-BINDING NUCLEAR
PROTEIN GSP1


(Encephalitozoon
cuniculi)
PF00071
(Ras)
4 ILE A  85
PHE A  49
GLY A 159
LEU A 183
None
0.86A 4ze3A-4djtA:
undetectable
4ze3A-4djtA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eff AROMATIC-AMINO-ACID
AMINOTRANSFERASE


(Burkholderia
pseudomallei)
PF00155
(Aminotran_1_2)
4 PHE A 342
ILE A 343
GLY A 354
LEU A 398
None
0.82A 4ze3A-4effA:
undetectable
4ze3A-4effA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdu PUTATIVE MULTIPLE
INOSITOL
POLYPHOSPHATE
HISTIDINE
PHOSPHATASE 1


(Bacteroides
thetaiotaomicron)
PF00328
(His_Phos_2)
4 PHE A 408
ILE A 392
GLY A 335
THR A 339
None
0.91A 4ze3A-4fduA:
undetectable
4ze3A-4fduA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g59 M152 PROTEIN

(Murid
betaherpesvirus
1)
PF11624
(M157)
4 PHE C  78
PHE C  95
GLY C 147
THR C 118
None
0.90A 4ze3A-4g59C:
undetectable
4ze3A-4g59C:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gbs PUTATIVE LIPOPROTEIN

(Bacteroides
fragilis)
PF14064
(HmuY)
4 TYR A 219
PHE A 215
ILE A 198
PHE A  43
None
0.88A 4ze3A-4gbsA:
undetectable
4ze3A-4gbsA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4has SORTING NEXIN-27

(Homo sapiens)
PF00787
(PX)
4 TYR A 251
ILE A 174
GLY A 262
LEU A 216
None
0.88A 4ze3A-4hasA:
undetectable
4ze3A-4hasA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hjl NAPHTHALENE
1,2-DIOXYGENASE
SUBUNIT ALPHA


(Pseudomonas sp.
C18)
PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A)
4 PHE A 432
GLY A 247
THR A 243
LEU A 443
None
0.91A 4ze3A-4hjlA:
undetectable
4ze3A-4hjlA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i3f SERINE HYDROLASE
CCSP0084


(Cycloclasticus
sp. P1)
PF12697
(Abhydrolase_6)
4 PHE A  63
PHE A 193
GLY A  33
LEU A 140
None
None
CL  A 301 (-4.0A)
None
0.92A 4ze3A-4i3fA:
undetectable
4ze3A-4i3fA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mll BETA-LACTAMASE OXA-1

(Escherichia
coli)
PF00905
(Transpeptidase)
4 PHE A 243
ILE A 233
PHE A 229
GLY A 211
None
0.80A 4ze3A-4mllA:
undetectable
4ze3A-4mllA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN


(Pseudomonas
aeruginosa)
PF03480
(DctP)
4 PHE A 182
ILE A 172
GLY A 208
LEU A 216
None
0.92A 4ze3A-4nf0A:
undetectable
4ze3A-4nf0A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oqf PROTEIN RECA

(Mycobacterium
tuberculosis)
PF00154
(RecA)
4 TYR A  66
ILE A 193
GLY A  72
THR A 243
EDO  A 402 (-4.8A)
None
GOL  A 401 (-3.4A)
None
0.84A 4ze3A-4oqfA:
undetectable
4ze3A-4oqfA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p05 ARYLSULFATE
SULFOTRANSFERASE
ASST


(Escherichia
coli)
PF05935
(Arylsulfotrans)
PF17425
(Arylsulfotran_N)
4 TYR A 488
PHE A 449
ILE A 504
GLY A 517
None
0.91A 4ze3A-4p05A:
undetectable
4ze3A-4p05A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN


(Aequorea
victoria;
Homo sapiens)
PF00063
(Myosin_head)
PF01353
(GFP)
PF02736
(Myosin_N)
4 PHE A 312
ILE A 356
GLY A 425
LEU A 399
None
0.78A 4ze3A-4p7hA:
undetectable
4ze3A-4p7hA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pua GLUTATHIONE
S-TRANSFERASE


(Streptococcus
pneumoniae)
PF02798
(GST_N)
PF13410
(GST_C_2)
4 ILE A  80
GLY A  53
THR A  57
LEU A  75
GSH  A 302 ( 3.8A)
None
None
None
0.79A 4ze3A-4puaA:
undetectable
4ze3A-4puaA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q5w MATERNAL PROTEIN
TUDOR


(Drosophila
melanogaster)
PF00567
(TUDOR)
4 ILE A2086
GLY A2062
THR A2064
LEU A2046
None
0.90A 4ze3A-4q5wA:
undetectable
4ze3A-4q5wA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rz2 SITE-DETERMINING
PROTEIN


(Geobacillus
thermodenitrificans)
PF10609
(ParA)
4 PHE A 284
ILE A 119
PHE A 151
LEU A  78
None
0.84A 4ze3A-4rz2A:
undetectable
4ze3A-4rz2A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wy5 ESTERASE

(Rhizomucor
miehei)
PF07859
(Abhydrolase_3)
4 ILE A 134
PHE A  91
GLY A 163
LEU A 240
None
0.82A 4ze3A-4wy5A:
undetectable
4ze3A-4wy5A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xnu INTEGRAL MEMBRANE
PROTEIN-DOPAMINE
TRANSPORTER


(Drosophila
melanogaster)
PF00209
(SNF)
4 PHE A 325
ILE A 116
PHE A 319
THR A 535
41U  A 605 ( 4.7A)
None
None
None
0.92A 4ze3A-4xnuA:
undetectable
4ze3A-4xnuA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z37 PUTATIVE MIXED
POLYKETIDE
SYNTHASE/NON-RIBOSOM
AL PEPTIDE
SYNTHETASE


(Brevibacillus
brevis)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc)
4 TYR A2526
PHE A2365
ILE A2355
GLY A2381
None
0.90A 4ze3A-4z37A:
undetectable
4ze3A-4z37A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a6b N-ACETYL-BETA-D-GLUC
OSAMINIDASE


(Streptococcus
pneumoniae)
PF00728
(Glyco_hydro_20)
4 ILE D 617
GLY D 341
THR D 343
LEU D 494
None
0.82A 4ze3A-5a6bD:
undetectable
4ze3A-5a6bD:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b1q U14 PROTEIN

(Human
betaherpesvirus
6B)
PF04637
(Herpes_pp85)
4 PHE A 316
PHE A  20
GLY A  85
LEU A  63
None
0.82A 4ze3A-5b1qA:
undetectable
4ze3A-5b1qA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cml OSMC FAMILY PROTEIN

(Rhodothermus
marinus)
PF12146
(Hydrolase_4)
4 PHE A  34
ILE A 106
PHE A  38
LEU A 224
None
0.71A 4ze3A-5cmlA:
undetectable
4ze3A-5cmlA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d7z LACTOYLGLUTATHIONE
LYASE


(Zea mays)
PF00903
(Glyoxalase)
4 ILE A  90
PHE A 143
THR A  38
LEU A  79
None
0.92A 4ze3A-5d7zA:
undetectable
4ze3A-5d7zA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B


(Neotoma lepida)
PF00067
(p450)
4 TYR A  79
ILE A  84
GLY A 366
LEU A  52
None
0.90A 4ze3A-5e0eA:
29.9
4ze3A-5e0eA:
24.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5fsa CYP51 VARIANT1

(Candida
albicans)
PF00067
(p450)
7 TYR A 118
PHE A 126
ILE A 131
PHE A 228
GLY A 307
THR A 311
LEU A 376
X2N  A 590 ( 4.0A)
X2N  A 590 (-4.8A)
X2N  A 590 (-4.2A)
X2N  A 590 (-4.9A)
X2N  A 590 (-3.5A)
HEM  A 580 (-3.6A)
X2N  A 590 (-4.3A)
0.51A 4ze3A-5fsaA:
57.7
4ze3A-5fsaA:
59.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gyz LUCIFERIN
4-MONOOXYGENASE


(Photinus
pyralis)
PF00501
(AMP-binding)
4 ILE A 434
GLY A 341
THR A 345
LEU A 418
AMP  A 501 ( 4.5A)
7BV  A 500 (-3.9A)
None
None
0.84A 4ze3A-5gyzA:
undetectable
4ze3A-5gyzA:
22.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5hs1 LANOSTEROL 14-ALPHA
DEMETHYLASE


(Saccharomyces
cerevisiae)
PF00067
(p450)
7 TYR A 126
PHE A 134
ILE A 139
PHE A 236
GLY A 314
THR A 318
LEU A 380
VOR  A 602 ( 3.8A)
VOR  A 602 (-4.7A)
VOR  A 602 (-4.3A)
VOR  A 602 (-4.4A)
VOR  A 602 (-3.0A)
HEM  A 601 (-3.4A)
VOR  A 602 (-4.0A)
0.45A 4ze3A-5hs1A:
63.3
4ze3A-5hs1A:
99.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jbo BETA-GLUCOSIDASE

(Trichoderma
harzianum)
PF00232
(Glyco_hydro_1)
4 PHE A 275
ILE A 274
GLY A 312
THR A 383
None
0.90A 4ze3A-5jboA:
undetectable
4ze3A-5jboA:
21.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5jlc LANOSTEROL 14-ALPHA
DEMETHYLASE


([Candida]
glabrata)
PF00067
(p450)
7 TYR A 127
PHE A 135
ILE A 140
PHE A 237
GLY A 315
THR A 319
LEU A 381
1YN  A 602 ( 3.8A)
1YN  A 602 ( 4.6A)
1YN  A 602 (-4.4A)
1YN  A 602 (-4.5A)
1YN  A 602 ( 3.6A)
HEM  A 601 ( 3.5A)
1YN  A 602 ( 4.7A)
0.61A 4ze3A-5jlcA:
59.0
4ze3A-5jlcA:
83.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kyv LUCIFERIN
4-MONOOXYGENASE


(Photinus
pyralis)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
4 ILE A 434
GLY A 341
THR A 345
LEU A 418
SLU  A 601 ( 4.3A)
SLU  A 601 (-4.0A)
None
None
0.85A 4ze3A-5kyvA:
undetectable
4ze3A-5kyvA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lp5 ROD
SHAPE-DETERMINING
PROTEIN (MREC)


(Helicobacter
pylori)
PF04085
(MreC)
4 PHE C 204
ILE C 203
GLY C 136
LEU C 114
None
0.89A 4ze3A-5lp5C:
undetectable
4ze3A-5lp5C:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oyp STRUCTURAL PROTEIN
VP3


(Sacbrood virus)
no annotation 4 TYR C 172
ILE C 116
GLY C  87
THR C 182
None
0.91A 4ze3A-5oypC:
undetectable
4ze3A-5oypC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uhk O-GLCNACASE
TIM-BARREL DOMAIN


(Homo sapiens)
PF07555
(NAGidase)
4 PHE A 145
ILE A 198
PHE A 191
GLY A 140
None
0.87A 4ze3A-5uhkA:
undetectable
4ze3A-5uhkA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ujz HEMAGGLUTININ HA1
HEMAGGLUTININ HA2


(Influenza A
virus)
PF00509
(Hemagglutinin)
4 TYR B 522
ILE A   9
GLY B 513
LEU A 321
None
0.84A 4ze3A-5ujzB:
undetectable
4ze3A-5ujzB:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wka BETA-GLUCOSIDASE

(metagenome)
no annotation 4 ILE A 284
GLY A 288
THR A 368
LEU A 112
None
0.80A 4ze3A-5wkaA:
undetectable
4ze3A-5wkaA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wti CRISPR-ASSOCIATED
PROTEIN


(Bacillus
thermoamylovorans)
no annotation 4 ILE Z 800
GLY Z 867
THR Z 519
LEU Z 477
None
0.91A 4ze3A-5wtiZ:
undetectable
4ze3A-5wtiZ:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xaj FABHM14C10 HEAVY
CHAIN


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
4 TYR A  59
ILE A  70
PHE A 106
GLY A  33
None
0.92A 4ze3A-5xajA:
undetectable
4ze3A-5xajA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xbp 3NT OXYGENASE ALPHA
SUBUNIT


(Diaphorobacter
sp. DS2)
PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A)
4 PHE A 430
GLY A 245
THR A 241
LEU A 441
None
0.90A 4ze3A-5xbpA:
undetectable
4ze3A-5xbpA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xqo PCRGLX PROTEIN

(Penicillium
chrysogenum)
no annotation 4 ILE A 411
GLY A 387
THR A 485
LEU A 491
None
0.77A 4ze3A-5xqoA:
undetectable
4ze3A-5xqoA:
10.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ay4 CYP51, STEROL
14ALPHA-DEMETHYLASE


(Naegleria
fowleri)
no annotation 5 TYR A 107
PHE A 114
PHE A 292
THR A 297
LEU A 358
TPF  A 506 (-4.2A)
TPF  A 506 (-4.4A)
TPF  A 506 ( 4.0A)
HEM  A 501 (-3.4A)
TPF  A 506 ( 4.4A)
1.36A 4ze3A-6ay4A:
42.9
4ze3A-6ay4A:
33.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6azh TETR FAMILY
TRANSCRIPTIONAL
REGULATOR


(Clostridium
perfringens)
no annotation 4 PHE A   9
ILE A  13
GLY A  58
LEU A  90
None
0.84A 4ze3A-6azhA:
2.7
4ze3A-6azhA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fsa -

(-)
no annotation 4 PHE A 312
ILE A 356
GLY A 425
LEU A 399
None
0.89A 4ze3A-6fsaA:
undetectable
4ze3A-6fsaA:
undetectable