SIMILAR PATTERNS OF AMINO ACIDS FOR 4ZE3_A_TPFA602_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a2o | CHEB METHYLESTERASE (Salmonellaenterica) |
PF00072(Response_reg)PF01339(CheB_methylest) | 4 | PHE A 199GLY A 167THR A 281LEU A 330 | None | 0.84A | 4ze3A-1a2oA:0.0 | 4ze3A-1a2oA:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c30 | CARBAMOYL PHOSPHATESYNTHETASE: LARGESUBUNIT (Escherichiacoli) |
PF02142(MGS)PF02786(CPSase_L_D2)PF02787(CPSase_L_D3) | 4 | PHE A 928GLY A1046THR A1043LEU A 907 | NoneNoneORN A4010 ( 4.9A)ORN A4010 (-4.0A) | 0.85A | 4ze3A-1c30A:0.0 | 4ze3A-1c30A:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1chd | CHEB METHYLESTERASE (Salmonellaenterica) |
PF01339(CheB_methylest) | 4 | PHE A 199GLY A 167THR A 281LEU A 330 | None | 0.84A | 4ze3A-1chdA:undetectable | 4ze3A-1chdA:16.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dfx | DESULFOFERRODOXIN (Desulfovibriodesulfuricans) |
PF01880(Desulfoferrodox)PF06397(Desulfoferrod_N) | 4 | TYR A 7ILE A 15GLY A 119THR A 41 | None | 0.85A | 4ze3A-1dfxA:undetectable | 4ze3A-1dfxA:13.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ej6 | LAMBDA1 (Reovirus sp.) |
no annotation | 4 | PHE B 831ILE B 522PHE B 733LEU B 864 | None | 0.80A | 4ze3A-1ej6B:0.7 | 4ze3A-1ej6B:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kho | ALPHA-TOXIN (Clostridiumperfringens) |
PF00882(Zn_dep_PLPC)PF01477(PLAT) | 4 | PHE A 192ILE A 179PHE A 196GLY A 231 | None | 0.88A | 4ze3A-1khoA:1.8 | 4ze3A-1khoA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l0q | SURFACE LAYERPROTEIN (Methanosarcinamazei) |
PF00801(PKD)PF10282(Lactonase) | 4 | PHE A 294ILE A 6GLY A 248THR A 217 | None | 0.89A | 4ze3A-1l0qA:undetectable | 4ze3A-1l0qA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1llc | L-LACTATEDEHYDROGENASE (Lactobacilluscasei) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | ILE A 281PHE A 200GLY A 193THR A 165 | None | 0.92A | 4ze3A-1llcA:undetectable | 4ze3A-1llcA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oa1 | HYDROXYLAMINEREDUCTASE (Desulfovibriovulgaris) |
PF03063(Prismane) | 4 | PHE A 61ILE A 41GLY A 65THR A 69 | None | 0.88A | 4ze3A-1oa1A:undetectable | 4ze3A-1oa1A:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rf5 | 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATESYNTHASE (Streptococcuspneumoniae) |
PF00275(EPSP_synthase) | 5 | PHE A 238ILE A 316PHE A 417GLY A 387LEU A 3 | None | 1.47A | 4ze3A-1rf5A:undetectable | 4ze3A-1rf5A:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tdt | TETRAHYDRODIPICOLINATE-N-SUCCINYLTRANSFERASE (Mycobacteriumbovis) |
PF00132(Hexapep)PF14602(Hexapep_2)PF14805(THDPS_N_2) | 4 | ILE A 177GLY A 153THR A 138LEU A 158 | None | 0.89A | 4ze3A-1tdtA:undetectable | 4ze3A-1tdtA:17.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ud9 | DNA POLYMERASESLIDING CLAMP A (Sulfurisphaeratokodaii) |
PF00705(PCNA_N)PF02747(PCNA_C) | 4 | TYR A 5PHE A 27ILE A 34LEU A 210 | None | 0.91A | 4ze3A-1ud9A:undetectable | 4ze3A-1ud9A:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1urj | MAJOR DNA-BINDINGPROTEIN (Humanalphaherpesvirus1) |
PF00747(Viral_DNA_bp) | 4 | PHE A 97GLY A 141THR A 139LEU A 176 | None | 0.87A | 4ze3A-1urjA:undetectable | 4ze3A-1urjA:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wom | SIGMA FACTOR SIGBREGULATION PROTEINRSBQ (Bacillussubtilis) |
PF12697(Abhydrolase_6) | 4 | PHE A 41ILE A 21GLY A 262LEU A 214 | None | 0.78A | 4ze3A-1womA:undetectable | 4ze3A-1womA:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x8v | CYTOCHROME P450 51 (Mycobacteriumtuberculosis) |
PF00067(p450) | 4 | TYR A 76PHE A 83THR A 260LEU A 321 | ESL A 471 ( 3.8A)NoneHEM A 470 (-3.6A)HEM A 470 (-4.1A) | 0.93A | 4ze3A-1x8vA:35.3 | 4ze3A-1x8vA:28.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2epk | N-ACETYL-BETA-D-GLUCOSAMINIDASE (Streptococcusgordonii) |
PF00728(Glyco_hydro_20) | 4 | ILE X 618GLY X 342THR X 344LEU X 495 | None | 0.89A | 4ze3A-2epkX:undetectable | 4ze3A-2epkX:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fna | CONSERVEDHYPOTHETICAL PROTEIN (Sulfolobussolfataricus) |
PF01637(ATPase_2) | 4 | ILE A 45PHE A 208THR A 246LEU A 2 | NoneNoneADP A 500 (-3.5A)ADP A 500 ( 4.9A) | 0.93A | 4ze3A-2fnaA:1.4 | 4ze3A-2fnaA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iqi | HYPOTHETICAL PROTEINXCC0632 (Xanthomonascampestris) |
PF03886(ABC_trans_aux) | 4 | TYR A 123PHE A 103ILE A 109GLY A 197 | None | 0.92A | 4ze3A-2iqiA:undetectable | 4ze3A-2iqiA:16.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o7r | CXE CARBOXYLESTERASE (Actinidiaeriantha) |
PF07859(Abhydrolase_3) | 4 | PHE A 104ILE A 103GLY A 92LEU A 222 | NoneNone4PA A 369 (-3.5A)None | 0.76A | 4ze3A-2o7rA:undetectable | 4ze3A-2o7rA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ozj | CUPIN 2, CONSERVEDBARREL (Desulfitobacteriumhafniense) |
no annotation | 4 | TYR A 61ILE A 63PHE A 44GLY A 97 | None | 0.81A | 4ze3A-2ozjA:undetectable | 4ze3A-2ozjA:12.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2reb | REC A (Escherichiacoli) |
PF00154(RecA) | 4 | TYR A 65ILE A 192GLY A 71THR A 242 | None | 0.85A | 4ze3A-2rebA:undetectable | 4ze3A-2rebA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rfo | NUCLEOPORIN NIC96 (Saccharomycescerevisiae) |
PF04097(Nic96) | 4 | TYR A 556PHE A 534ILE A 537GLY A 509 | None | 0.87A | 4ze3A-2rfoA:undetectable | 4ze3A-2rfoA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wed | PENICILLOPEPSIN (Penicilliumjanthinellum) |
PF00026(Asp) | 4 | ILE A 260PHE A 208GLY A 210LEU A 219 | None | 0.90A | 4ze3A-2wedA:undetectable | 4ze3A-2wedA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2whk | MANNANENDO-1,4-BETA-MANNOSIDASE (Bacillussubtilis) |
PF02156(Glyco_hydro_26) | 5 | PHE A 243ILE A 249PHE A 276GLY A 268LEU A 313 | None | 1.38A | 4ze3A-2whkA:undetectable | 4ze3A-2whkA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wlc | POLYSIALIC ACIDO-ACETYLTRANSFERASE (Neisseriameningitidis) |
PF00132(Hexapep) | 4 | ILE A 139GLY A 104THR A 86LEU A 109 | NoneEDO A1218 (-3.5A)NoneNone | 0.79A | 4ze3A-2wlcA:undetectable | 4ze3A-2wlcA:17.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a21 | PUTATIVE SECRETEDALPHA-GALACTOSIDASE (Streptomycesavermitilis) |
PF00652(Ricin_B_lectin)PF16499(Melibiase_2) | 4 | TYR A 357ILE A 381GLY A 421LEU A 261 | NoneGOL A 915 (-4.7A)NoneNone | 0.87A | 4ze3A-3a21A:undetectable | 4ze3A-3a21A:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c8e | YGHU, GLUTATHIONES-TRANSFERASEHOMOLOGUE (Escherichiacoli) |
PF02798(GST_N)PF13410(GST_C_2) | 4 | ILE A 82GLY A 55THR A 59LEU A 47 | GSH A 289 (-3.7A)NoneNoneNone | 0.92A | 4ze3A-3c8eA:undetectable | 4ze3A-3c8eA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | TYR A 65ILE A 192GLY A 71THR A 242 | NoneNoneADP A 502 (-3.3A)None | 0.89A | 4ze3A-3cmtA:undetectable | 4ze3A-3cmtA:15.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | TYR A1065ILE A1192GLY A1071THR A1242 | NoneNoneADP A1502 (-3.4A)None | 0.90A | 4ze3A-3cmtA:undetectable | 4ze3A-3cmtA:15.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | TYR A2065ILE A2192GLY A2071THR A2242 | NoneNoneADP A2502 (-3.4A)None | 0.90A | 4ze3A-3cmtA:undetectable | 4ze3A-3cmtA:15.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | TYR A3065ILE A3192GLY A3071THR A3242 | NoneNoneADP A3502 (-3.4A)None | 0.89A | 4ze3A-3cmtA:undetectable | 4ze3A-3cmtA:15.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | TYR A4065ILE A4192GLY A4071THR A4242 | NoneNoneADP A4502 (-3.2A)None | 0.90A | 4ze3A-3cmtA:undetectable | 4ze3A-3cmtA:15.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmv | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | TYR A1065ILE A1192GLY A1071THR A1242 | NoneNoneANP A1400 (-3.1A)None | 0.89A | 4ze3A-3cmvA:undetectable | 4ze3A-3cmvA:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmv | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | TYR A2065ILE A2192GLY A2071THR A2242 | NoneNoneANP A2400 (-3.7A)None | 0.92A | 4ze3A-3cmvA:undetectable | 4ze3A-3cmvA:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d8b | FIDGETIN-LIKEPROTEIN 1 (Homo sapiens) |
PF00004(AAA)PF09336(Vps4_C) | 4 | PHE A 486ILE A 539PHE A 524LEU A 559 | None | 0.83A | 4ze3A-3d8bA:undetectable | 4ze3A-3d8bA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dy5 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | TYR A 171ILE A 143GLY A 139LEU A 292 | None | 0.78A | 4ze3A-3dy5A:2.1 | 4ze3A-3dy5A:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewn | THIJ/PFPI FAMILYPROTEIN (Pseudomonassyringae groupgenomosp. 3) |
PF01965(DJ-1_PfpI) | 4 | PHE A 76ILE A 56PHE A 211LEU A 160 | None | 0.86A | 4ze3A-3ewnA:undetectable | 4ze3A-3ewnA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fmb | DIMERIC PROTEIN OFUNKNOWN FUNCTION ANDFERREDOXIN-LIKE FOLD (Bacteroidesfragilis) |
PF07876(Dabb) | 4 | PHE A 8ILE A 57GLY A 82LEU A 33 | None | 0.73A | 4ze3A-3fmbA:undetectable | 4ze3A-3fmbA:14.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g0o | 3-HYDROXYISOBUTYRATEDEHYDROGENASE (Salmonellaenterica) |
PF03446(NAD_binding_2)PF14833(NAD_binding_11) | 4 | PHE A 60GLY A 10THR A 32LEU A 45 | None | 0.92A | 4ze3A-3g0oA:undetectable | 4ze3A-3g0oA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hd6 | AMMONIUM TRANSPORTERRH TYPE C (Homo sapiens) |
PF00909(Ammonium_transp) | 4 | TYR A 241GLY A 180THR A 183LEU A 170 | None | 0.92A | 4ze3A-3hd6A:undetectable | 4ze3A-3hd6A:23.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hfw | PROTEINADP-RIBOSYLARGININEHYDROLASE (Homo sapiens) |
PF03747(ADP_ribosyl_GH) | 4 | TYR A 279ILE A 309GLY A 171LEU A 195 | None | 0.91A | 4ze3A-3hfwA:undetectable | 4ze3A-3hfwA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hrd | NICOTINATEDEHYDROGENASEFAD-SUBUNIT (Eubacteriumbarkeri) |
PF00941(FAD_binding_5)PF03450(CO_deh_flav_C) | 4 | PHE C 77ILE C 80GLY C 112LEU C 148 | FAD C 900 (-4.2A)NoneFAD C 900 ( 4.3A)None | 0.87A | 4ze3A-3hrdC:undetectable | 4ze3A-3hrdC:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i9v | NADH-QUINONEOXIDOREDUCTASESUBUNIT 1 (Thermusthermophilus) |
PF01512(Complex1_51K)PF10531(SLBB)PF10589(NADH_4Fe-4S) | 4 | ILE 1 149PHE 1 169GLY 1 130LEU 1 224 | None | 0.85A | 4ze3A-3i9v1:undetectable | 4ze3A-3i9v1:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iz3 | VIRAL STRUCTURALPROTEIN 5 (Cypovirus 1) |
no annotation | 4 | PHE D 31ILE D 19PHE D 179THR D 233 | None | 0.77A | 4ze3A-3iz3D:undetectable | 4ze3A-3iz3D:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jaz | VIRAL STRUCTURALPROTEIN 5 (Cypovirus 1) |
no annotation | 4 | PHE D 31ILE D 19PHE D 179THR D 233 | None | 0.92A | 4ze3A-3jazD:undetectable | 4ze3A-3jazD:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jr3 | NAD-DEPENDENTDEACETYLASE (Thermotogamaritima) |
PF02146(SIR2) | 4 | ILE A 245PHE A 6THR A 18LEU A 187 | None | 0.90A | 4ze3A-3jr3A:undetectable | 4ze3A-3jr3A:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kt4 | PKHD-TYPEHYDROXYLASE TPA1 (Saccharomycescerevisiae) |
PF10637(Ofd1_CTDD)PF13661(2OG-FeII_Oxy_4) | 4 | PHE A 129ILE A 168GLY A 56LEU A 189 | None | 0.93A | 4ze3A-3kt4A:undetectable | 4ze3A-3kt4A:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l8k | DIHYDROLIPOYLDEHYDROGENASE (Sulfolobussolfataricus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | PHE A 189ILE A 185PHE A 74THR A 164 | None | 0.88A | 4ze3A-3l8kA:undetectable | 4ze3A-3l8kA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lpp | SUCRASE-ISOMALTASE (Homo sapiens) |
PF00088(Trefoil)PF01055(Glyco_hydro_31)PF16863(NtCtMGAM_N) | 4 | PHE A 589ILE A 594GLY A 243THR A 229 | None | 0.83A | 4ze3A-3lppA:undetectable | 4ze3A-3lppA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m3p | GLUTAMINE AMIDOTRANSFERASE (Methylobacillusflagellatus) |
PF00117(GATase) | 4 | PHE A 144ILE A 146GLY A 172LEU A 128 | None | 0.91A | 4ze3A-3m3pA:undetectable | 4ze3A-3m3pA:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3omb | EXTRACELLULARSOLUTE-BINDINGPROTEIN, FAMILY 1 (Bifidobacteriumlongum) |
PF01547(SBP_bac_1) | 4 | PHE A 486ILE A 485PHE A 220GLY A 246 | None | 0.87A | 4ze3A-3ombA:undetectable | 4ze3A-3ombA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3onq | REGULATOR OFPOLYKETIDE SYNTHASEEXPRESSION (Bifidobacteriumadolescentis) |
PF13556(HTH_30) | 4 | ILE A 71GLY A 57THR A 140LEU A 137 | None | 0.80A | 4ze3A-3onqA:undetectable | 4ze3A-3onqA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qfk | UNCHARACTERIZEDPROTEIN (Staphylococcusaureus) |
PF00149(Metallophos)PF02872(5_nucleotid_C) | 4 | PHE A 88ILE A 52PHE A 134LEU A 260 | None | 0.81A | 4ze3A-3qfkA:undetectable | 4ze3A-3qfkA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tk8 | 2,3,4,5-TETRAHYDROPYRIDINE-2,6-DICARBOXYLATEN-SUCCINYLTRANSFERASE (Burkholderiapseudomallei) |
PF00132(Hexapep)PF14602(Hexapep_2)PF14805(THDPS_N_2) | 4 | ILE A 216GLY A 192THR A 177LEU A 197 | None | 0.88A | 4ze3A-3tk8A:undetectable | 4ze3A-3tk8A:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v8b | PUTATIVEDEHYDROGENASE,POSSIBLY3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 4 | ILE A 92GLY A 117THR A 121LEU A 35 | None | 0.93A | 4ze3A-3v8bA:undetectable | 4ze3A-3v8bA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x0v | L-LYSINE OXIDASE (Trichodermaviride) |
PF01593(Amino_oxidase) | 4 | TYR A 92ILE A 90GLY A 230THR A 51 | None | 0.87A | 4ze3A-3x0vA:undetectable | 4ze3A-3x0vA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4awe | ENDO-BETA-D-1,4-MANNANASE (Neurosporasitophila) |
PF00150(Cellulase) | 4 | PHE A 54ILE A 115PHE A 346GLY A 42 | None | 0.89A | 4ze3A-4aweA:undetectable | 4ze3A-4aweA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4db1 | MYOSIN-7 (Homo sapiens) |
PF00063(Myosin_head)PF02736(Myosin_N) | 4 | PHE A 312ILE A 356GLY A 425LEU A 399 | None | 0.81A | 4ze3A-4db1A:undetectable | 4ze3A-4db1A:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4djt | GTP-BINDING NUCLEARPROTEIN GSP1 (Encephalitozooncuniculi) |
PF00071(Ras) | 4 | ILE A 85PHE A 49GLY A 159LEU A 183 | None | 0.86A | 4ze3A-4djtA:undetectable | 4ze3A-4djtA:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eff | AROMATIC-AMINO-ACIDAMINOTRANSFERASE (Burkholderiapseudomallei) |
PF00155(Aminotran_1_2) | 4 | PHE A 342ILE A 343GLY A 354LEU A 398 | None | 0.82A | 4ze3A-4effA:undetectable | 4ze3A-4effA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdu | PUTATIVE MULTIPLEINOSITOLPOLYPHOSPHATEHISTIDINEPHOSPHATASE 1 (Bacteroidesthetaiotaomicron) |
PF00328(His_Phos_2) | 4 | PHE A 408ILE A 392GLY A 335THR A 339 | None | 0.91A | 4ze3A-4fduA:undetectable | 4ze3A-4fduA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g59 | M152 PROTEIN (Muridbetaherpesvirus1) |
PF11624(M157) | 4 | PHE C 78PHE C 95GLY C 147THR C 118 | None | 0.90A | 4ze3A-4g59C:undetectable | 4ze3A-4g59C:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gbs | PUTATIVE LIPOPROTEIN (Bacteroidesfragilis) |
PF14064(HmuY) | 4 | TYR A 219PHE A 215ILE A 198PHE A 43 | None | 0.88A | 4ze3A-4gbsA:undetectable | 4ze3A-4gbsA:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4has | SORTING NEXIN-27 (Homo sapiens) |
PF00787(PX) | 4 | TYR A 251ILE A 174GLY A 262LEU A 216 | None | 0.88A | 4ze3A-4hasA:undetectable | 4ze3A-4hasA:12.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hjl | NAPHTHALENE1,2-DIOXYGENASESUBUNIT ALPHA (Pseudomonas sp.C18) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A) | 4 | PHE A 432GLY A 247THR A 243LEU A 443 | None | 0.91A | 4ze3A-4hjlA:undetectable | 4ze3A-4hjlA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i3f | SERINE HYDROLASECCSP0084 (Cycloclasticussp. P1) |
PF12697(Abhydrolase_6) | 4 | PHE A 63PHE A 193GLY A 33LEU A 140 | NoneNone CL A 301 (-4.0A)None | 0.92A | 4ze3A-4i3fA:undetectable | 4ze3A-4i3fA:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mll | BETA-LACTAMASE OXA-1 (Escherichiacoli) |
PF00905(Transpeptidase) | 4 | PHE A 243ILE A 233PHE A 229GLY A 211 | None | 0.80A | 4ze3A-4mllA:undetectable | 4ze3A-4mllA:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nf0 | PROBABLEC4-DICARBOXYLATE-BINDING PROTEIN (Pseudomonasaeruginosa) |
PF03480(DctP) | 4 | PHE A 182ILE A 172GLY A 208LEU A 216 | None | 0.92A | 4ze3A-4nf0A:undetectable | 4ze3A-4nf0A:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqf | PROTEIN RECA (Mycobacteriumtuberculosis) |
PF00154(RecA) | 4 | TYR A 66ILE A 193GLY A 72THR A 243 | EDO A 402 (-4.8A)NoneGOL A 401 (-3.4A)None | 0.84A | 4ze3A-4oqfA:undetectable | 4ze3A-4oqfA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p05 | ARYLSULFATESULFOTRANSFERASEASST (Escherichiacoli) |
PF05935(Arylsulfotrans)PF17425(Arylsulfotran_N) | 4 | TYR A 488PHE A 449ILE A 504GLY A 517 | None | 0.91A | 4ze3A-4p05A:undetectable | 4ze3A-4p05A:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p7h | MYOSIN-7,GREENFLUORESCENT PROTEIN (Aequoreavictoria;Homo sapiens) |
PF00063(Myosin_head)PF01353(GFP)PF02736(Myosin_N) | 4 | PHE A 312ILE A 356GLY A 425LEU A 399 | None | 0.78A | 4ze3A-4p7hA:undetectable | 4ze3A-4p7hA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pua | GLUTATHIONES-TRANSFERASE (Streptococcuspneumoniae) |
PF02798(GST_N)PF13410(GST_C_2) | 4 | ILE A 80GLY A 53THR A 57LEU A 75 | GSH A 302 ( 3.8A)NoneNoneNone | 0.79A | 4ze3A-4puaA:undetectable | 4ze3A-4puaA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q5w | MATERNAL PROTEINTUDOR (Drosophilamelanogaster) |
PF00567(TUDOR) | 4 | ILE A2086GLY A2062THR A2064LEU A2046 | None | 0.90A | 4ze3A-4q5wA:undetectable | 4ze3A-4q5wA:15.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rz2 | SITE-DETERMININGPROTEIN (Geobacillusthermodenitrificans) |
PF10609(ParA) | 4 | PHE A 284ILE A 119PHE A 151LEU A 78 | None | 0.84A | 4ze3A-4rz2A:undetectable | 4ze3A-4rz2A:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wy5 | ESTERASE (Rhizomucormiehei) |
PF07859(Abhydrolase_3) | 4 | ILE A 134PHE A 91GLY A 163LEU A 240 | None | 0.82A | 4ze3A-4wy5A:undetectable | 4ze3A-4wy5A:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xnu | INTEGRAL MEMBRANEPROTEIN-DOPAMINETRANSPORTER (Drosophilamelanogaster) |
PF00209(SNF) | 4 | PHE A 325ILE A 116PHE A 319THR A 535 | 41U A 605 ( 4.7A)NoneNoneNone | 0.92A | 4ze3A-4xnuA:undetectable | 4ze3A-4xnuA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z37 | PUTATIVE MIXEDPOLYKETIDESYNTHASE/NON-RIBOSOMAL PEPTIDESYNTHETASE (Brevibacillusbrevis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 4 | TYR A2526PHE A2365ILE A2355GLY A2381 | None | 0.90A | 4ze3A-4z37A:undetectable | 4ze3A-4z37A:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a6b | N-ACETYL-BETA-D-GLUCOSAMINIDASE (Streptococcuspneumoniae) |
PF00728(Glyco_hydro_20) | 4 | ILE D 617GLY D 341THR D 343LEU D 494 | None | 0.82A | 4ze3A-5a6bD:undetectable | 4ze3A-5a6bD:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b1q | U14 PROTEIN (Humanbetaherpesvirus6B) |
PF04637(Herpes_pp85) | 4 | PHE A 316PHE A 20GLY A 85LEU A 63 | None | 0.82A | 4ze3A-5b1qA:undetectable | 4ze3A-5b1qA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cml | OSMC FAMILY PROTEIN (Rhodothermusmarinus) |
PF12146(Hydrolase_4) | 4 | PHE A 34ILE A 106PHE A 38LEU A 224 | None | 0.71A | 4ze3A-5cmlA:undetectable | 4ze3A-5cmlA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d7z | LACTOYLGLUTATHIONELYASE (Zea mays) |
PF00903(Glyoxalase) | 4 | ILE A 90PHE A 143THR A 38LEU A 79 | None | 0.92A | 4ze3A-5d7zA:undetectable | 4ze3A-5d7zA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e0e | CYTOCHROME P450FAMILY 2 SUBFAMILY B (Neotoma lepida) |
PF00067(p450) | 4 | TYR A 79ILE A 84GLY A 366LEU A 52 | None | 0.90A | 4ze3A-5e0eA:29.9 | 4ze3A-5e0eA:24.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5fsa | CYP51 VARIANT1 (Candidaalbicans) |
PF00067(p450) | 7 | TYR A 118PHE A 126ILE A 131PHE A 228GLY A 307THR A 311LEU A 376 | X2N A 590 ( 4.0A)X2N A 590 (-4.8A)X2N A 590 (-4.2A)X2N A 590 (-4.9A)X2N A 590 (-3.5A)HEM A 580 (-3.6A)X2N A 590 (-4.3A) | 0.51A | 4ze3A-5fsaA:57.7 | 4ze3A-5fsaA:59.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gyz | LUCIFERIN4-MONOOXYGENASE (Photinuspyralis) |
PF00501(AMP-binding) | 4 | ILE A 434GLY A 341THR A 345LEU A 418 | AMP A 501 ( 4.5A)7BV A 500 (-3.9A)NoneNone | 0.84A | 4ze3A-5gyzA:undetectable | 4ze3A-5gyzA:22.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hs1 | LANOSTEROL 14-ALPHADEMETHYLASE (Saccharomycescerevisiae) |
PF00067(p450) | 7 | TYR A 126PHE A 134ILE A 139PHE A 236GLY A 314THR A 318LEU A 380 | VOR A 602 ( 3.8A)VOR A 602 (-4.7A)VOR A 602 (-4.3A)VOR A 602 (-4.4A)VOR A 602 (-3.0A)HEM A 601 (-3.4A)VOR A 602 (-4.0A) | 0.45A | 4ze3A-5hs1A:63.3 | 4ze3A-5hs1A:99.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jbo | BETA-GLUCOSIDASE (Trichodermaharzianum) |
PF00232(Glyco_hydro_1) | 4 | PHE A 275ILE A 274GLY A 312THR A 383 | None | 0.90A | 4ze3A-5jboA:undetectable | 4ze3A-5jboA:21.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jlc | LANOSTEROL 14-ALPHADEMETHYLASE ([Candida]glabrata) |
PF00067(p450) | 7 | TYR A 127PHE A 135ILE A 140PHE A 237GLY A 315THR A 319LEU A 381 | 1YN A 602 ( 3.8A)1YN A 602 ( 4.6A)1YN A 602 (-4.4A)1YN A 602 (-4.5A)1YN A 602 ( 3.6A)HEM A 601 ( 3.5A)1YN A 602 ( 4.7A) | 0.61A | 4ze3A-5jlcA:59.0 | 4ze3A-5jlcA:83.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kyv | LUCIFERIN4-MONOOXYGENASE (Photinuspyralis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | ILE A 434GLY A 341THR A 345LEU A 418 | SLU A 601 ( 4.3A)SLU A 601 (-4.0A)NoneNone | 0.85A | 4ze3A-5kyvA:undetectable | 4ze3A-5kyvA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lp5 | RODSHAPE-DETERMININGPROTEIN (MREC) (Helicobacterpylori) |
PF04085(MreC) | 4 | PHE C 204ILE C 203GLY C 136LEU C 114 | None | 0.89A | 4ze3A-5lp5C:undetectable | 4ze3A-5lp5C:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oyp | STRUCTURAL PROTEINVP3 (Sacbrood virus) |
no annotation | 4 | TYR C 172ILE C 116GLY C 87THR C 182 | None | 0.91A | 4ze3A-5oypC:undetectable | 4ze3A-5oypC:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uhk | O-GLCNACASETIM-BARREL DOMAIN (Homo sapiens) |
PF07555(NAGidase) | 4 | PHE A 145ILE A 198PHE A 191GLY A 140 | None | 0.87A | 4ze3A-5uhkA:undetectable | 4ze3A-5uhkA:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ujz | HEMAGGLUTININ HA1HEMAGGLUTININ HA2 (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | TYR B 522ILE A 9GLY B 513LEU A 321 | None | 0.84A | 4ze3A-5ujzB:undetectable | 4ze3A-5ujzB:14.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wka | BETA-GLUCOSIDASE (metagenome) |
no annotation | 4 | ILE A 284GLY A 288THR A 368LEU A 112 | None | 0.80A | 4ze3A-5wkaA:undetectable | 4ze3A-5wkaA:10.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wti | CRISPR-ASSOCIATEDPROTEIN (Bacillusthermoamylovorans) |
no annotation | 4 | ILE Z 800GLY Z 867THR Z 519LEU Z 477 | None | 0.91A | 4ze3A-5wtiZ:undetectable | 4ze3A-5wtiZ:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xaj | FABHM14C10 HEAVYCHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | TYR A 59ILE A 70PHE A 106GLY A 33 | None | 0.92A | 4ze3A-5xajA:undetectable | 4ze3A-5xajA:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xbp | 3NT OXYGENASE ALPHASUBUNIT (Diaphorobactersp. DS2) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A) | 4 | PHE A 430GLY A 245THR A 241LEU A 441 | None | 0.90A | 4ze3A-5xbpA:undetectable | 4ze3A-5xbpA:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xqo | PCRGLX PROTEIN (Penicilliumchrysogenum) |
no annotation | 4 | ILE A 411GLY A 387THR A 485LEU A 491 | None | 0.77A | 4ze3A-5xqoA:undetectable | 4ze3A-5xqoA:10.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6ay4 | CYP51, STEROL14ALPHA-DEMETHYLASE (Naegleriafowleri) |
no annotation | 5 | TYR A 107PHE A 114PHE A 292THR A 297LEU A 358 | TPF A 506 (-4.2A)TPF A 506 (-4.4A)TPF A 506 ( 4.0A)HEM A 501 (-3.4A)TPF A 506 ( 4.4A) | 1.36A | 4ze3A-6ay4A:42.9 | 4ze3A-6ay4A:33.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6azh | TETR FAMILYTRANSCRIPTIONALREGULATOR (Clostridiumperfringens) |
no annotation | 4 | PHE A 9ILE A 13GLY A 58LEU A 90 | None | 0.84A | 4ze3A-6azhA:2.7 | 4ze3A-6azhA:10.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fsa | - (-) |
no annotation | 4 | PHE A 312ILE A 356GLY A 425LEU A 399 | None | 0.89A | 4ze3A-6fsaA:undetectable | 4ze3A-6fsaA:undetectable |