SIMILAR PATTERNS OF AMINO ACIDS FOR 4ZBR_A_NPSA603_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b41 | ACETYLCHOLINESTERASE (Homo sapiens) |
PF00135(COesterase) | 5 | ALA A 31LEU A 17LEU A 33ALA A 62SER A 128 | None | 1.21A | 4zbrA-1b41A:undetectable | 4zbrA-1b41A:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1igq | TRANSCRIPTIONALREPRESSOR PROTEINKORB (Escherichiacoli) |
PF06613(KorB_C) | 5 | ARG A 316ALA A 318ASP A 338LEU A 334ALA A 345 | None | 1.07A | 4zbrA-1igqA:undetectable | 4zbrA-1igqA:7.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k1b | B-CELL LYMPHOMA3-ENCODED PROTEIN (Homo sapiens) |
PF00023(Ank)PF12796(Ank_2) | 5 | ALA A 200ASP A 158ALA A 171SER A 219ALA A 215 | None | 1.13A | 4zbrA-1k1bA:undetectable | 4zbrA-1k1bA:16.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ll2 | GLYCOGENIN-1 (Oryctolaguscuniculus) |
PF01501(Glyco_transf_8) | 5 | ALA A 153LEU A 167LEU A 84SER A 69ALA A 70 | None | 1.14A | 4zbrA-1ll2A:undetectable | 4zbrA-1ll2A:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p88 | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Escherichiacoli) |
PF00275(EPSP_synthase) | 5 | ALA A 138LEU A 108ALA A 104LEU A 135ALA A 132 | None | 1.22A | 4zbrA-1p88A:undetectable | 4zbrA-1p88A:17.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sk7 | HYPOTHETICAL PROTEINPA-HO (Pseudomonasaeruginosa) |
PF01126(Heme_oxygenase) | 5 | ARG A 80ALA A 84LEU A 147LEU A 54ALA A 51 | None | 1.18A | 4zbrA-1sk7A:undetectable | 4zbrA-1sk7A:17.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 8 | ARG A 209ALA A 213ASP A 324LEU A 327LEU A 347ALA A 350SER A 480LEU A 481 | DKA A1001 ( 4.6A)DKA A1001 ( 4.0A)DKA A1001 (-4.7A)DKA A1001 (-4.1A)DKA A1002 ( 4.3A)DKA A1002 ( 3.8A)DKA A1002 (-3.4A)None | 0.48A | 4zbrA-1tf0A:46.9 | 4zbrA-1tf0A:76.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 7 | ARG A 209ALA A 213LEU A 327LEU A 347ALA A 350LYS A 351SER A 480 | DKA A1001 ( 4.6A)DKA A1001 ( 4.0A)DKA A1001 (-4.1A)DKA A1002 ( 4.3A)DKA A1002 ( 3.8A)DKA A1002 (-2.6A)DKA A1002 (-3.4A) | 0.78A | 4zbrA-1tf0A:46.9 | 4zbrA-1tf0A:76.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tj7 | ARGININOSUCCINATELYASE (Escherichiacoli) |
PF00206(Lyase_1)PF14698(ASL_C2) | 5 | ASP A 337LEU A 336LEU A 135ALA A 131LEU A 346 | None | 1.16A | 4zbrA-1tj7A:undetectable | 4zbrA-1tj7A:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u6z | EXOPOLYPHOSPHATASE (Escherichiacoli) |
PF02541(Ppx-GppA) | 5 | ALA A 95LEU A 51SER A 20LEU A 47ALA A 48 | NoneNoneSO4 A 701 (-3.0A)NoneNone | 1.21A | 4zbrA-1u6zA:undetectable | 4zbrA-1u6zA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ulq | PUTATIVE ACETYL-COAACETYLTRANSFERASE (Thermusthermophilus) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | ALA A 259LEU A 21SER A 35LEU A 34ALA A 31 | None | 1.09A | 4zbrA-1ulqA:0.0 | 4zbrA-1ulqA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdw | TRYPTOPHAN SYNTHASEALPHA CHAIN (Pyrococcusfuriosus) |
PF00290(Trp_syntA) | 5 | ARG A 185ALA A 186ASP A 146LEU A 162ALA A 140 | None | 0.95A | 4zbrA-1wdwA:undetectable | 4zbrA-1wdwA:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wr6 | ADP-RIBOSYLATIONFACTOR BINDINGPROTEIN GGA3 (Homo sapiens) |
PF03127(GAT) | 5 | LEU A 276LEU A 262ALA A 266SER A 287LEU A 286 | None | 1.01A | 4zbrA-1wr6A:2.4 | 4zbrA-1wr6A:12.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x9d | ENDOPLASMICRETICULUMMANNOSYL-OLIGOSACCHARIDE1,2-ALPHA-MANNOSIDASE (Homo sapiens) |
PF01532(Glyco_hydro_47) | 5 | LEU A 408ALA A 355SER A 346LEU A 345ALA A 342 | None | 1.16A | 4zbrA-1x9dA:2.6 | 4zbrA-1x9dA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yd8 | ADP-RIBOSYLATIONFACTOR BINDINGPROTEIN GGA3 (Homo sapiens) |
PF03127(GAT) | 5 | LEU G 276LEU G 262ALA G 266SER G 287LEU G 286 | None | 1.16A | 4zbrA-1yd8G:undetectable | 4zbrA-1yd8G:11.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zel | HYPOTHETICAL PROTEINRV2827C (Mycobacteriumtuberculosis) |
PF09407(AbiEi_1)PF13338(AbiEi_4) | 5 | ALA A 106LEU A 154LEU A 183ALA A 182SER A 193 | None | 1.14A | 4zbrA-1zelA:undetectable | 4zbrA-1zelA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ahw | PUTATIVE ENZYME YDIF (Escherichiacoli) |
PF01144(CoA_trans) | 6 | ALA A 91LEU A 154ALA A 106SER A 80LEU A 82ALA A 83 | None | 1.25A | 4zbrA-2ahwA:undetectable | 4zbrA-2ahwA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b8n | GLYCERATE KINASE,PUTATIVE (Thermotogamaritima) |
PF05161(MOFRL)PF13660(DUF4147) | 5 | ALA A 27LEU A 32ALA A 55SER A 122ALA A 48 | None | 1.21A | 4zbrA-2b8nA:undetectable | 4zbrA-2b8nA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cul | GLUCOSE-INHIBITEDDIVISION PROTEINA-RELATED PROTEIN,PROBABLEOXIDOREDUCTASE (Thermusthermophilus) |
PF01134(GIDA) | 5 | LEU A 81LEU A 22ALA A 23LEU A 223ALA A 224 | None | 1.20A | 4zbrA-2culA:undetectable | 4zbrA-2culA:17.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dpn | GLYCEROL KINASE (Thermusthermophilus) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | ALA A 288LEU A 299LEU A 247LEU A 253ALA A 252 | None | 1.20A | 4zbrA-2dpnA:undetectable | 4zbrA-2dpnA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fez | PROBABLE REGULATORYPROTEIN EMBR (Mycobacteriumtuberculosis) |
PF00486(Trans_reg_C)PF00498(FHA)PF03704(BTAD) | 5 | ALA A 178LEU A 211ALA A 214SER A 265ALA A 262 | None | 1.18A | 4zbrA-2fezA:undetectable | 4zbrA-2fezA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fgg | HYPOTHETICAL PROTEINRV2632C/MT2708 (Mycobacteriumtuberculosis) |
PF08962(DUF1876) | 5 | ALA A 26ALA A 43SER A 66LEU A 65ALA A 62 | None | 1.03A | 4zbrA-2fggA:undetectable | 4zbrA-2fggA:9.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fon | PEROXISOMAL ACYL-COAOXIDASE 1A (Solanumlycopersicum) |
PF01756(ACOX)PF02770(Acyl-CoA_dh_M)PF14749(Acyl-CoA_ox_N) | 5 | ARG A 597ALA A 308ASP A 326LEU A 7SER A 602 | None | 1.15A | 4zbrA-2fonA:undetectable | 4zbrA-2fonA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h5g | DELTA1-PYRROLINE-5-CARBOXYLATE SYNTHETASE (Homo sapiens) |
PF00171(Aldedh) | 5 | ALA A 492LEU A 392ALA A 393LEU A 524ALA A 523 | None | 1.07A | 4zbrA-2h5gA:undetectable | 4zbrA-2h5gA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jjx | URIDYLATE KINASE (Bacillusanthracis) |
PF00696(AA_kinase) | 6 | ALA A 149LEU A 158LEU A 210ALA A 156LEU A 204ALA A 205 | None | 1.45A | 4zbrA-2jjxA:undetectable | 4zbrA-2jjxA:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k3o | TUSP1 (Nephilaantipodiana) |
PF12042(RP1-2) | 5 | ALA A 78LEU A 15ALA A 16LEU A 107ALA A 108 | None | 1.19A | 4zbrA-2k3oA:1.9 | 4zbrA-2k3oA:12.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l6h | FOCAL ADHESIONKINASE 1, LINKER,PAXILLIN (Gallus gallus;unidentified) |
PF03623(Focal_AT) | 5 | ALA A 121LEU A 125LEU A 21LEU A 51ALA A 50 | None | 1.10A | 4zbrA-2l6hA:5.0 | 4zbrA-2l6hA:14.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l7b | APOLIPOPROTEIN E (Homo sapiens) |
PF01442(Apolipoprotein) | 5 | ASP A 153ALA A 100SER A 263LEU A 261ALA A 259 | None | 1.10A | 4zbrA-2l7bA:3.0 | 4zbrA-2l7bA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nql | ISOMERASE/LACTONIZING ENZYME (Agrobacteriumfabrum) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 381ASP A 355LEU A 354LEU A 13ALA A 320 | None | 1.19A | 4zbrA-2nqlA:undetectable | 4zbrA-2nqlA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oce | HYPOTHETICAL PROTEINPA5201 (Pseudomonasaeruginosa) |
PF00575(S1)PF09371(Tex_N)PF12836(HHH_3)PF16921(Tex_YqgF) | 5 | ALA A 505ASP A 456LEU A 510ALA A 508LEU A 558 | None | 1.20A | 4zbrA-2oceA:undetectable | 4zbrA-2oceA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oi8 | PUTATIVE REGULATORYPROTEIN SCO4313 (Streptomycescoelicolor) |
PF00440(TetR_N) | 5 | ALA A 138LEU A 214LEU A 92SER A 85ALA A 82 | None | 0.98A | 4zbrA-2oi8A:3.2 | 4zbrA-2oi8A:17.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q5o | PHENYLPYRUVATEDECARBOXYLASE (Azospirillumbrasilense) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | ALA A 141LEU A 3ALA A 170LEU A 7ALA A 4 | None | 1.15A | 4zbrA-2q5oA:undetectable | 4zbrA-2q5oA:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v0j | BIFUNCTIONAL PROTEINGLMU (Haemophilusinfluenzae) |
PF00132(Hexapep)PF12804(NTP_transf_3) | 5 | ASP A 208LEU A 184ALA A 185LEU A 198ALA A 83 | None | 1.12A | 4zbrA-2v0jA:undetectable | 4zbrA-2v0jA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xdr | BETAINE ALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00171(Aldedh) | 5 | ALA A 75LEU A 113ALA A 110LEU A 167ALA A 164 | None | 1.19A | 4zbrA-2xdrA:undetectable | 4zbrA-2xdrA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yzw | ADP-RIBOSYLGLYCOHYDROLASE (Thermusthermophilus) |
PF03747(ADP_ribosyl_GH) | 5 | ALA A 135LEU A 16ALA A 290LEU A 65ALA A 66 | None | 1.14A | 4zbrA-2yzwA:undetectable | 4zbrA-2yzwA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqp | PROBABLE SECDFPROTEIN-EXPORTMEMBRANE PROTEIN (Thermusthermophilus) |
PF02355(SecD_SecF)PF07549(Sec_GG) | 5 | ALA A 625LEU A 388ALA A 392LEU A 403ALA A 400 | None | 1.02A | 4zbrA-3aqpA:undetectable | 4zbrA-3aqpA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cax | UNCHARACTERIZEDPROTEIN PF0695 (Pyrococcusfuriosus) |
PF01814(Hemerythrin)PF13596(PAS_10) | 5 | ALA A 240LEU A 142SER A 248LEU A 247ALA A 139 | None | 1.13A | 4zbrA-3caxA:3.2 | 4zbrA-3caxA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cin | MYO-INOSITOL-1-PHOSPHATESYNTHASE-RELATEDPROTEIN (Thermotogamaritima) |
PF01658(Inos-1-P_synth)PF07994(NAD_binding_5) | 5 | ALA A 167LEU A 202ALA A 178LEU A 196ALA A 197 | None | 1.15A | 4zbrA-3cinA:undetectable | 4zbrA-3cinA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e1s | EXODEOXYRIBONUCLEASEV, SUBUNIT RECD (Deinococcusradiodurans) |
PF13538(UvrD_C_2)PF13604(AAA_30)PF14490(HHH_4) | 6 | ALA A 309LEU A 283LEU A 708ALA A 707LEU A 479ALA A 478 | None | 1.30A | 4zbrA-3e1sA:undetectable | 4zbrA-3e1sA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ek5 | URIDYLATE KINASE (Xanthomonascampestris) |
PF00696(AA_kinase) | 5 | ALA A 150LEU A 159LEU A 210LEU A 204ALA A 205 | None | 1.17A | 4zbrA-3ek5A:undetectable | 4zbrA-3ek5A:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eya | PYRUVATEDEHYDROGENASE[CYTOCHROME] (Escherichiacoli) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | ALA A 228LEU A 269ALA A 266LEU A 336ALA A 335 | None | 1.18A | 4zbrA-3eyaA:undetectable | 4zbrA-3eyaA:23.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3go9 | INSULINASE FAMILYPROTEASE (Yersinia pestis) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 5 | ASP A 300LEU A 301LEU A 383LYS A 379LEU A 386 | PEG A 607 (-3.3A)NoneNoneNoneNone | 1.13A | 4zbrA-3go9A:undetectable | 4zbrA-3go9A:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h90 | FERROUS-IRON EFFLUXPUMP FIEF (Escherichiacoli) |
PF01545(Cation_efflux)PF16916(ZT_dimer) | 5 | ALA A 82ALA A 149SER A 204LEU A 205ALA A 201 | None | 1.06A | 4zbrA-3h90A:2.5 | 4zbrA-3h90A:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjr | EXTRACELLULAR SERINEPROTEASE (Aeromonassobria) |
PF00082(Peptidase_S8)PF01483(P_proprotein) | 5 | ALA A 352LEU A 423ALA A 62LEU A 364ALA A 422 | None | 1.10A | 4zbrA-3hjrA:undetectable | 4zbrA-3hjrA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iup | PUTATIVENADPH:QUINONEOXIDOREDUCTASE (Cupriaviduspinatubonensis) |
no annotation | 5 | ALA A 240LEU A 235ALA A 234LEU A 264ALA A 263 | None | 1.12A | 4zbrA-3iupA:undetectable | 4zbrA-3iupA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j3i | CAPSID PROTEIN (Penicilliumchrysogenumvirus) |
no annotation | 5 | ASP A 820LEU A 817ALA A 811LEU A 878ALA A 918 | None | 1.13A | 4zbrA-3j3iA:undetectable | 4zbrA-3j3iA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k5w | CARBOHYDRATE KINASE (Helicobacterpylori) |
PF01256(Carb_kinase)PF03853(YjeF_N) | 5 | LEU A 241ALA A 296SER A 261LEU A 257ALA A 256 | None | 1.21A | 4zbrA-3k5wA:undetectable | 4zbrA-3k5wA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lkd | TYPE IRESTRICTION-MODIFICATION SYSTEMMETHYLTRANSFERASESUBUNIT (Streptococcusthermophilus) |
PF02384(N6_Mtase)PF12161(HsdM_N) | 5 | ALA A 103ASP A 110LEU A 67SER A 62LEU A 63 | None | 1.12A | 4zbrA-3lkdA:undetectable | 4zbrA-3lkdA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oja | ANOPHELESPLASMODIUM-RESPONSIVE LEUCINE-RICHREPEAT PROTEIN 1LEUCINE-RICH IMMUNEMOLECULE 1 (Anophelesgambiae) |
PF00560(LRR_1)PF13855(LRR_8) | 5 | ASP B 681LEU B 680LEU A 487ALA A 483LEU B 690 | None | 1.13A | 4zbrA-3ojaB:undetectable | 4zbrA-3ojaB:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rij | SC_2CX5 (Thermusthermophilus) |
PF04073(tRNA_edit) | 5 | ALA A 60LEU A 85LEU A 95ALA A 87ALA A 94 | None | 1.19A | 4zbrA-3rijA:undetectable | 4zbrA-3rijA:15.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT M (Escherichiacoli) |
no annotation | 5 | ALA M 394LEU M 478ALA M 347LEU M 355ALA M 352 | None | 1.14A | 4zbrA-3rkoM:undetectable | 4zbrA-3rkoM:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rx8 | CELLULASE (Alicyclobacillusacidocaldarius) |
PF00759(Glyco_hydro_9)PF02927(CelD_N) | 5 | ALA A 427LEU A 423LEU A 415LEU A 531ALA A 530 | None | 0.98A | 4zbrA-3rx8A:undetectable | 4zbrA-3rx8A:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3snx | PUTATIVE SUSD-LIKECARBOHYDRATE BINDINGPROTEIN (Bacteroidesthetaiotaomicron) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 6 | ARG A 146ALA A 142ASP A 199LEU A 202LEU A 49ALA A 46 | None | 1.40A | 4zbrA-3snxA:undetectable | 4zbrA-3snxA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tsd | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Bacillusanthracis) |
PF00478(IMPDH)PF00571(CBS) | 5 | ALA A 225ASP A 251LEU A 250LEU A 240ALA A 239 | None | 1.20A | 4zbrA-3tsdA:undetectable | 4zbrA-3tsdA:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3udu | 3-ISOPROPYLMALATEDEHYDROGENASE (Campylobacterjejuni) |
PF00180(Iso_dh) | 5 | ALA A 42LEU A 9ALA A 10SER A 93LEU A 56 | None | 1.17A | 4zbrA-3uduA:undetectable | 4zbrA-3uduA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v0t | PERAKINE REDUCTASE (Rauvolfiaserpentina) |
PF00248(Aldo_ket_red) | 5 | LEU A 181LEU A 264ALA A 263LEU A 293ALA A 292 | None | 1.11A | 4zbrA-3v0tA:undetectable | 4zbrA-3v0tA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v2h | D-BETA-HYDROXYBUTYRATE DEHYDROGENASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 5 | ALA A 237ASP A 239LEU A 22ALA A 25ALA A 5 | None | 1.18A | 4zbrA-3v2hA:undetectable | 4zbrA-3v2hA:17.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zxy | SUBTILISIN-LIKEPROTEIN (Prochlorondidemni) |
PF00082(Peptidase_S8) | 5 | LEU A 146ALA A 228SER A 254LEU A 282ALA A 279 | None | 1.12A | 4zbrA-3zxyA:undetectable | 4zbrA-3zxyA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4abx | DNA REPAIR PROTEINRECN (Deinococcusradiodurans) |
no annotation | 5 | ASP A 314LEU A 313LEU A 226SER A 324LEU A 323 | None | 1.15A | 4zbrA-4abxA:3.6 | 4zbrA-4abxA:15.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b52 | BACILLOLYSIN (Paenibacilluspolymyxa) |
PF01447(Peptidase_M4)PF02868(Peptidase_M4_C) | 5 | ALA A 274LEU A 263ALA A 258SER A 297ALA A 294 | None | 1.13A | 4zbrA-4b52A:2.1 | 4zbrA-4b52A:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ckg | ARF-GAP WITHCOILED-COIL, ANKREPEAT AND PHDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00169(PH)PF16746(BAR_3) | 5 | LEU A 159ALA A 155SER A 133LEU A 134ALA A 162 | None | 0.90A | 4zbrA-4ckgA:2.0 | 4zbrA-4ckgA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fso | PROBABLE PORIN (Pseudomonasaeruginosa) |
PF03573(OprD) | 5 | ARG A 236ALA A 293SER A 232LEU A 260ALA A 261 | NoneNoneNoneC8E A 504 ( 4.7A)None | 1.21A | 4zbrA-4fsoA:undetectable | 4zbrA-4fsoA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hb1 | DHP1 (syntheticconstruct) |
no annotation | 5 | LEU A 4LEU A 114ALA A 118LEU A 14ALA A 111 | None | 1.10A | 4zbrA-4hb1A:2.1 | 4zbrA-4hb1A:10.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l62 | TRANSCRIPTIONALREGULATOR (Pseudomonasaeruginosa) |
PF00440(TetR_N)PF16925(TetR_C_13) | 5 | ASP A 71LEU A 67LEU A 136LEU A 140ALA A 158 | None | 1.19A | 4zbrA-4l62A:5.1 | 4zbrA-4l62A:15.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m8s | PUTATIVE3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (Neisseriameningitidis) |
PF13561(adh_short_C2) | 5 | ALA A 227ASP A 229LEU A 28ALA A 31ALA A 11 | None | 1.12A | 4zbrA-4m8sA:undetectable | 4zbrA-4m8sA:16.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mtn | TRANSCRIPTIONTERMINATION FACTORNUSA (Planctopiruslimnophila) |
PF00575(S1)PF08529(NusA_N)PF13184(KH_5)PF14520(HHH_5) | 5 | ALA A 259LEU A 252LEU A 303LEU A 299ALA A 199 | None | 1.15A | 4zbrA-4mtnA:undetectable | 4zbrA-4mtnA:20.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 5 | ALA A 213LEU A 327LEU A 347SER A 480LEU A 481 | NPS A 602 (-3.3A)NPS A 602 ( 4.7A)NPS A 602 ( 4.2A)NoneNone | 0.55A | 4zbrA-4po0A:50.2 | 4zbrA-4po0A:71.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 6 | ARG A 209ALA A 213ASP A 324LEU A 327LEU A 347LEU A 481 | NPS A 602 (-3.6A)NPS A 602 (-3.3A)NPS A 602 ( 4.4A)NPS A 602 ( 4.7A)NPS A 602 ( 4.2A)None | 0.73A | 4zbrA-4po0A:50.2 | 4zbrA-4po0A:71.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rsx | TYPE III EFFECTORHOPA1 (Pseudomonassyringae groupgenomosp. 3) |
no annotation | 5 | ALA A 140LEU A 349SER A 363LEU A 360ALA A 348 | None | 1.21A | 4zbrA-4rsxA:2.0 | 4zbrA-4rsxA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wjm | RIBOKINASE:CARBOHYDRATE KINASE, PFKB (Brucellaabortus) |
PF00294(PfkB) | 5 | ARG A 287ALA A 288LEU A 42ALA A 303ALA A 257 | EDO A 404 (-3.6A)NoneNoneNoneNone | 1.12A | 4zbrA-4wjmA:undetectable | 4zbrA-4wjmA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x82 | ZINC TRANSPORTERZIP4 (Pteropus alecto) |
no annotation | 5 | ALA B 92LEU B 46LEU B 180LEU B 176ALA B 177 | None | 1.08A | 4zbrA-4x82B:undetectable | 4zbrA-4x82B:19.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xci | THERMOSOME SUBUNITALPHA (Sulfolobussolfataricus) |
PF00118(Cpn60_TCP1) | 5 | ALA A 127LEU A 427ALA A 431LEU A 449ALA A 424 | None | 1.06A | 4zbrA-4xciA:undetectable | 4zbrA-4xciA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xci | THERMOSOME SUBUNITALPHA (Sulfolobussolfataricus) |
PF00118(Cpn60_TCP1) | 5 | ALA A 514LEU A 78LEU A 103LEU A 449ALA A 448 | None | 1.04A | 4zbrA-4xciA:undetectable | 4zbrA-4xciA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xcm | CELL WALL-BINDINGENDOPEPTIDASE-RELATED PROTEIN (Thermusthermophilus) |
PF00877(NLPC_P60)PF01476(LysM) | 5 | ALA A 215LEU A 192LEU A 209SER A 129LEU A 132 | None | 1.16A | 4zbrA-4xcmA:undetectable | 4zbrA-4xcmA:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xri | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF03810(IBN_N)PF13513(HEAT_EZ) | 5 | ALA A 143LEU A 104LEU A 155SER A 208ALA A 204 | None | 1.06A | 4zbrA-4xriA:undetectable | 4zbrA-4xriA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ypl | LON PROTEASE (Meiothermustaiwanensis) |
PF00004(AAA)PF05362(Lon_C) | 5 | ALA A 684LEU A 769ALA A 597SER A 678ALA A 679 | NoneNoneNone4KZ A 801 (-1.4A)4KZ A 801 (-3.5A) | 1.12A | 4zbrA-4yplA:2.2 | 4zbrA-4yplA:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zz7 | METHYLMALONATE-SEMIALDEHYDEDEHYDROGENASE (Oceanimonasdoudoroffii) |
PF00171(Aldedh) | 5 | ALA A 286ASP A 370LEU A 368LEU A 268ALA A 264 | None | 1.12A | 4zbrA-4zz7A:undetectable | 4zbrA-4zz7A:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5arm | CSP3 (Methylosinustrichosporium) |
no annotation | 5 | ALA A 68LEU A 87ALA A 91LEU A 21ALA A 128 | None | 1.18A | 4zbrA-5armA:undetectable | 4zbrA-5armA:13.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b8h | TYPE IIIPANTOTHENATE KINASE (Burkholderiacenocepacia) |
PF03309(Pan_kinase) | 5 | ALA A 135LEU A 146LEU A 212ALA A 208ALA A 215 | None | 0.95A | 4zbrA-5b8hA:undetectable | 4zbrA-5b8hA:18.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 8 | ALA A 212ASP A 323LEU A 326LEU A 346ALA A 349SER A 479LEU A 480ALA A 481 | CZE A 613 ( 3.7A)CZE A 613 ( 4.7A)CZE A 613 ( 4.7A)CZE A 613 ( 3.8A)CZE A 613 ( 4.7A)NoneNoneCZE A 613 ( 4.6A) | 0.40A | 4zbrA-5dqfA:55.4 | 4zbrA-5dqfA:99.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 6 | ARG A 208ALA A 212LEU A 346SER A 479LEU A 480ALA A 481 | CZE A 613 ( 3.5A)CZE A 613 ( 3.7A)CZE A 613 ( 3.8A)NoneNoneCZE A 613 ( 4.6A) | 0.83A | 4zbrA-5dqfA:55.4 | 4zbrA-5dqfA:99.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 7 | ALA A 213ASP A 324LEU A 327LEU A 347ALA A 350SER A 480LEU A 481 | None | 0.38A | 4zbrA-5ghkA:47.5 | 4zbrA-5ghkA:76.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gw5 | T-COMPLEX PROTEIN 1SUBUNIT DELTA (Saccharomycescerevisiae) |
PF00118(Cpn60_TCP1) | 6 | ALA d 127LEU d 425ALA d 429SER d 445LEU d 447ALA d 444 | None | 1.35A | 4zbrA-5gw5d:undetectable | 4zbrA-5gw5d:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gw5 | T-COMPLEX PROTEIN 1SUBUNIT ETA (Saccharomycescerevisiae) |
PF00118(Cpn60_TCP1) | 5 | ALA h 510LEU h 83LEU h 108LEU h 446ALA h 445 | None | 1.03A | 4zbrA-5gw5h:undetectable | 4zbrA-5gw5h:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kij | ENDOPLASMICRETICULUMMANNOSYL-OLIGOSACCHARIDE1,2-ALPHA-MANNOSIDASE (Homo sapiens) |
PF01532(Glyco_hydro_47) | 5 | LEU A 408ALA A 355SER A 346LEU A 345ALA A 342 | None | 1.19A | 4zbrA-5kijA:undetectable | 4zbrA-5kijA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ko3 | ORF1A (Middle Eastrespiratorysyndrome-relatedcoronavirus) |
PF08715(Viral_protease) | 5 | ALA A 136ASP A 144LEU A 151ALA A 150LYS A 87 | ACT A 405 ( 3.6A)NoneACT A 405 ( 4.5A)NoneACT A 402 (-2.6A) | 1.21A | 4zbrA-5ko3A:undetectable | 4zbrA-5ko3A:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n3u | PHYCOCYANOBILINLYASE SUBUNIT ALPHA (Nostoc sp. PCC7120) |
no annotation | 5 | ALA A 120LEU A 155LEU A 112ALA A 154ALA A 108 | None | 1.17A | 4zbrA-5n3uA:undetectable | 4zbrA-5n3uA:8.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n3u | PHYCOCYANOBILINLYASE SUBUNIT ALPHA (Nostoc sp. PCC7120) |
no annotation | 5 | ALA A 233LEU A 215ALA A 214LEU A 244ALA A 243 | None | 1.11A | 4zbrA-5n3uA:undetectable | 4zbrA-5n3uA:8.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nd1 | CAPSID PROTEIN (Rosellinianecatrixquadrivirus 1) |
no annotation | 5 | ALA A 524LEU A 519LEU A 65SER A 61LEU A 60 | None | 1.06A | 4zbrA-5nd1A:undetectable | 4zbrA-5nd1A:7.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 9 | ARG A 208ALA A 212ASP A 323LEU A 326LEU A 346ALA A 349LYS A 350SER A 479LEU A 480 | None | 0.60A | 4zbrA-5oriA:50.7 | 4zbrA-5oriA:75.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ud6 | DIHYDRODIPICOLINATESYNTHASE (Cyanidioschyzonmerolae) |
no annotation | 5 | ALA A 268ASP A 286LEU A 295LEU A 257ALA A 256 | None | 1.22A | 4zbrA-5ud6A:undetectable | 4zbrA-5ud6A:9.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vrq | ANKYRINREPEAT-CONTAININGPROTEIN (Legionellapneumophila) |
no annotation | 5 | ALA A 101LEU A 169ALA A 172LEU A 160ALA A 161 | None | 1.15A | 4zbrA-5vrqA:undetectable | 4zbrA-5vrqA:9.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wuf | PUTATIVE MEMBRANEPROTEIN (Colwelliapsychrerythraea) |
PF03458(UPF0126) | 5 | ALA A 190LEU A 92ALA A 96LEU A 153ALA A 154 | None | 1.07A | 4zbrA-5wufA:undetectable | 4zbrA-5wufA:17.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xde | THERMOPHILICDIBENZOTHIOPHENEDESULFURIZATIONENZYME C (Paenibacillussp. A11-2) |
PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N)PF08028(Acyl-CoA_dh_2) | 5 | ALA A 382LEU A 258ALA A 85SER A 204LEU A 205 | None | 0.85A | 4zbrA-5xdeA:3.6 | 4zbrA-5xdeA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 8 | ARG A 209ALA A 213ASP A 324LEU A 327LEU A 347ALA A 350SER A 480LEU A 481 | None | 0.46A | 4zbrA-5yxeA:45.8 | 4zbrA-5yxeA:14.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6a2f | - (-) |
no annotation | 5 | ALA A 64LEU A 79LEU A 96LEU A 90ALA A 91 | NoneLLP A 34 ( 3.9A)NoneNoneNone | 1.20A | 4zbrA-6a2fA:undetectable | 4zbrA-6a2fA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ane | POLY(ETHYLENETEREPHTHALATE)HYDROLASE (Ideonellasakaiensis) |
no annotation | 5 | ALA A 53LEU A 104ALA A 108SER A 148LEU A 149 | None | 1.20A | 4zbrA-6aneA:undetectable | 4zbrA-6aneA:8.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bfi | VIN1 (Oscarellapearsei) |
no annotation | 5 | ASP A 326LEU A 325LEU A 349ALA A 353LEU A 335 | None | 1.17A | 4zbrA-6bfiA:4.7 | 4zbrA-6bfiA:9.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ehs | HYDROGENASE-2 LARGECHAIN (Escherichiacoli) |
no annotation | 5 | LEU L 185ALA L 130SER L 121LEU L 123ALA L 122 | None | 1.19A | 4zbrA-6ehsL:undetectable | 4zbrA-6ehsL:8.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f72 | MTVAO615 (Thermothelomycesthermophila) |
no annotation | 5 | ALA A 287LEU A 264LEU A 278ALA A 266ALA A 277 | None | 1.07A | 4zbrA-6f72A:undetectable | 4zbrA-6f72A:9.76 |