SIMILAR PATTERNS OF AMINO ACIDS FOR 4ZBQ_A_DIFA601_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a4s BETAINE ALDEHYDE
DEHYDROGENASE

(Gadus morhua) 		PF00171
(Aldedh) 		5 VAL A 325
PHE A 381
LEU A 376
GLY A 337
LEU A 331
 None
 1.31A 4zbqA-1a4sA:
undetectable		 4zbqA-1a4sA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)

(Escherichia
coli) 		PF00549
(Ligase_CoA)
PF08442
(ATP-grasp_2) 		5 LEU B 173
VAL B 174
LEU B 110
GLY B 160
LEU B 167
 None
 1.06A 4zbqA-1cqiB:
2.1		 4zbqA-1cqiB:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gnx BETA-GLUCOSIDASE

(Streptomyces
sp.) 		PF00232
(Glyco_hydro_1) 		5 LEU A  83
SER A 431
LEU A 429
ARG A 403
SER A 463
 None
 1.22A 4zbqA-1gnxA:
0.0		 4zbqA-1gnxA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ib1 SEROTONIN
N-ACETYLTRANSFERASE

(Ovis aries) 		PF00583
(Acetyltransf_1) 		5 LEU E 164
VAL E 165
LEU E 140
GLY E 172
LEU E 158
 COT  E 401 (-4.6A)
None
None
None
COT  E 401 ( 4.8A)
 1.15A 4zbqA-1ib1E:
undetectable		 4zbqA-1ib1E:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jfx 1,4-BETA-N-ACETYLMUR
AMIDASE M1

(Streptomyces
coelicolor) 		PF01183
(Glyco_hydro_25) 		5 PHE A 123
LEU A  97
GLY A  72
SER A  70
ARG A  66
 None
None
None
CL  A1008 (-3.2A)
None
 1.31A 4zbqA-1jfxA:
undetectable		 4zbqA-1jfxA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jig DLP-2

(Bacillus
anthracis) 		PF00210
(Ferritin) 		5 LEU A 142
VAL A  99
LEU A  21
SER A 103
LEU A 135
 None
 1.16A 4zbqA-1jigA:
undetectable		 4zbqA-1jigA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		5 LEU A1076
LEU A1106
GLY A1137
SER A1115
LEU A1113
 None
 1.04A 4zbqA-1jl5A:
undetectable		 4zbqA-1jl5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfw CHITINASE B

(Arthrobacter
sp. TAD20) 		PF00704
(Glyco_hydro_18) 		5 VAL A  21
ASN A  20
PHE A 430
GLY A 408
LEU A 325
 None
 1.29A 4zbqA-1kfwA:
undetectable		 4zbqA-1kfwA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1paq TRANSLATION
INITIATION FACTOR
EIF-2B EPSILON
SUBUNIT

(Saccharomyces
cerevisiae) 		PF02020
(W2) 		5 LEU A 655
PHE A 622
LEU A 635
GLY A 619
SER A 661
 None
 1.32A 4zbqA-1paqA:
undetectable		 4zbqA-1paqA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ps6 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE

(Escherichia
coli) 		PF04166
(PdxA) 		5 LEU A  76
VAL A  36
LEU A 101
GLY A 119
LEU A 116
 None
 1.23A 4zbqA-1ps6A:
undetectable		 4zbqA-1ps6A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rj6 CARBONIC ANHYDRASE
XIV

(Mus musculus) 		PF00194
(Carb_anhydrase) 		5 LEU A 241
VAL A 242
ASN A 244
GLY A 104
LEU A 226
 None
 1.00A 4zbqA-1rj6A:
undetectable		 4zbqA-1rj6A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rkt PROTEIN YFIR

(Bacillus
subtilis) 		PF00440
(TetR_N) 		5 LEU A  92
PHE A 151
LEU A 142
SER A  87
LEU A  75
 None
 1.33A 4zbqA-1rktA:
2.9		 4zbqA-1rktA:
17.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		7 ASN A 391
PHE A 403
LEU A 407
ARG A 410
GLY A 434
ARG A 485
SER A 489
 None
 0.70A 4zbqA-1tf0A:
46.6		 4zbqA-1tf0A:
76.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		7 ASN A 391
PHE A 403
LEU A 407
GLY A 434
LEU A 453
ARG A 485
SER A 489
 None
 0.67A 4zbqA-1tf0A:
46.6		 4zbqA-1tf0A:
76.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		5 LEU A 387
ASN A 391
ARG A 410
ARG A 485
SER A 489
 None
 1.02A 4zbqA-1tf0A:
46.6		 4zbqA-1tf0A:
76.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		5 LEU A 387
ASN A 391
ARG A 410
LEU A 430
SER A 489
 None
 1.32A 4zbqA-1tf0A:
46.6		 4zbqA-1tf0A:
76.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ur1 ENDOXYLANASE

(Cellvibrio
mixtus) 		PF00331
(Glyco_hydro_10) 		5 LEU A  56
PHE A  93
LEU A  41
GLY A  48
SER A 331
 None
 1.21A 4zbqA-1ur1A:
undetectable		 4zbqA-1ur1A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w8s FRUCTOSE-BISPHOSPHAT
E ALDOLASE CLASS I

(Thermoproteus
tenax) 		PF01791
(DeoC) 		5 LEU A 221
VAL A 220
PHE A 213
LEU A 247
GLY A 203
 None
None
None
None
FBP  A 270 (-3.2A)
 1.33A 4zbqA-1w8sA:
undetectable		 4zbqA-1w8sA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wck BCLA PROTEIN

(Bacillus
anthracis) 		PF01391
(Collagen) 		5 LEU A  97
LEU A 151
GLY A 149
SER A 146
SER A 205
 None
 1.35A 4zbqA-1wckA:
undetectable		 4zbqA-1wckA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wf3 GTP-BINDING PROTEIN

(Thermus
thermophilus) 		PF01926
(MMR_HSR1)
PF07650
(KH_2) 		5 LEU A 163
VAL A 160
LEU A  50
GLY A  29
LEU A  24
 None
 1.35A 4zbqA-1wf3A:
undetectable		 4zbqA-1wf3A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a1f URIDYLATE KINASE

(Haemophilus
influenzae) 		PF00696
(AA_kinase) 		5 LEU A  86
VAL A  82
LEU A  18
GLY A  53
LEU A  57
 None
 1.32A 4zbqA-2a1fA:
undetectable		 4zbqA-2a1fA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f1s VIRAL CASP8 AND
FADD-LIKE APOPTOSIS
REGULATOR

(Molluscum
contagiosum
virus) 		PF01335
(DED) 		5 LEU A 141
VAL A 140
LEU A  27
GLY A 104
ARG A  97
 None
 1.05A 4zbqA-2f1sA:
undetectable		 4zbqA-2f1sA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fkj OUTER SURFACE
PROTEIN A

(Borreliella
burgdorferi) 		PF00820
(Lipoprotein_1) 		5 LEU A  41
VAL A  42
LEU A  88
GLY A  74
LEU A  34
 None
 1.25A 4zbqA-2fkjA:
undetectable		 4zbqA-2fkjA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2joe HYPOTHETICAL
LIPOPROTEIN YEHR

(Escherichia
coli) 		PF06998
(DUF1307) 		5 VAL A  30
PHE A  93
LEU A  96
GLY A 112
SER A  35
 None
 1.21A 4zbqA-2joeA:
undetectable		 4zbqA-2joeA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2khz C-MYC-RESPONSIVE
PROTEIN RCL

(Rattus
norvegicus) 		PF05014
(Nuc_deoxyrib_tr) 		5 ARG A 109
GLY A  16
SER A  87
ARG A 114
SER A 112
 None
 1.15A 4zbqA-2khzA:
undetectable		 4zbqA-2khzA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2osa N-CHIMAERIN

(Homo sapiens) 		PF00620
(RhoGAP) 		5 LEU A 450
VAL A 448
PHE A 459
LEU A 383
SER A 366
 None
 1.34A 4zbqA-2osaA:
undetectable		 4zbqA-2osaA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4y URIDYLATE KINASE

(Escherichia
coli) 		PF00696
(AA_kinase) 		5 LEU A  89
VAL A  85
LEU A  21
GLY A  56
LEU A  60
 None
None
None
GTP  A1243 (-3.3A)
None
 1.27A 4zbqA-2v4yA:
undetectable		 4zbqA-2v4yA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vdc GLUTAMATE SYNTHASE
[NADPH] LARGE CHAIN

(Azospirillum
brasilense) 		PF00310
(GATase_2)
PF01493
(GXGXG)
PF01645
(Glu_synthase)
PF04898
(Glu_syn_central) 		5 VAL A 758
PHE A 498
LEU A 730
GLY A 494
LEU A 622
 None
 1.31A 4zbqA-2vdcA:
undetectable		 4zbqA-2vdcA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2waw MOBA RELATE PROTEIN

(Mycobacterium
sp. DSM 3803) 		PF12804
(NTP_transf_3) 		5 LEU A 161
PHE A 146
LEU A  89
GLY A  98
LEU A 101
 None
 1.33A 4zbqA-2wawA:
undetectable		 4zbqA-2wawA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2we9 MOBA-RELATED PROTEIN

(Mycobacterium
tuberculosis) 		PF12804
(NTP_transf_3) 		5 LEU A 161
PHE A 146
LEU A  89
GLY A  98
LEU A 101
 None
 1.30A 4zbqA-2we9A:
undetectable		 4zbqA-2we9A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wgy CYTOCHROME P450 130

(Mycobacterium
tuberculosis) 		PF00067
(p450) 		5 VAL A 380
PHE A 144
GLY A 253
LEU A 259
ARG A 266
 None
IPA  A1408 (-4.0A)
None
None
None
 1.10A 4zbqA-2wgyA:
3.2		 4zbqA-2wgyA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2woz KELCH REPEAT AND BTB
DOMAIN-CONTAINING
PROTEIN 10

(Rattus
norvegicus) 		PF01344
(Kelch_1) 		5 VAL A 442
ASN A 441
PHE A 488
GLY A 453
SER A 338
 None
 1.12A 4zbqA-2wozA:
undetectable		 4zbqA-2wozA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2woz KELCH REPEAT AND BTB
DOMAIN-CONTAINING
PROTEIN 10

(Rattus
norvegicus) 		PF01344
(Kelch_1) 		5 VAL A 442
ASN A 441
PHE A 488
GLY A 454
SER A 338
 None
 1.36A 4zbqA-2wozA:
undetectable		 4zbqA-2wozA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xf2 CATALASE

(Penicillium
janthinellum) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		5 VAL A 539
ASN A 540
GLY A 593
LEU A 597
SER A 614
 None
 1.32A 4zbqA-2xf2A:
undetectable		 4zbqA-2xf2A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yh2 ESTERASE

(Pyrobaculum
calidifontis) 		PF07859
(Abhydrolase_3) 		5 ASN A 161
PHE A  87
LEU A 190
GLY A  86
LEU A 256
 None
 1.31A 4zbqA-2yh2A:
undetectable		 4zbqA-2yh2A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zkm 1-PHOSPHATIDYLINOSIT
OL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-2

(Homo sapiens) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		5 LEU X 131
VAL X 134
LEU X  17
GLY X  44
LEU X  47
 None
 1.16A 4zbqA-2zkmX:
undetectable		 4zbqA-2zkmX:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zqq METHYLGLUTACONYL-COA
HYDRATASE

(Homo sapiens) 		PF00378
(ECH_1) 		5 LEU A 224
GLY A 252
LEU A 243
ARG A 241
SER A 239
 None
 1.18A 4zbqA-2zqqA:
undetectable		 4zbqA-2zqqA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwv PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE

(Thermus
thermophilus) 		PF05175
(MTS) 		5 LEU A 107
ASN A  53
GLY A  57
SER A  60
LEU A  38
 None
 1.27A 4zbqA-2zwvA:
1.2		 4zbqA-2zwvA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3agr NUCLEOSIDE
TRIPHOSPHATE
HYDROLASE

(Neospora
caninum) 		PF01150
(GDA1_CD39) 		5 VAL A  91
LEU A 132
GLY A 127
LEU A 182
SER A 163
 None
 1.28A 4zbqA-3agrA:
undetectable		 4zbqA-3agrA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eex OUTER SURFACE
PROTEIN A

(Borreliella
burgdorferi) 		PF00820
(Lipoprotein_1) 		5 LEU A  41
VAL A  42
LEU A  88
GLY A  74
LEU A  34
 None
 1.26A 4zbqA-3eexA:
undetectable		 4zbqA-3eexA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gvz UNCHARACTERIZED
PROTEIN CV2077

(Chromobacterium
violaceum) 		PF03417
(AAT) 		5 LEU A 143
VAL A  91
PHE A 134
LEU A 163
LEU A 123
 None
 1.36A 4zbqA-3gvzA:
undetectable		 4zbqA-3gvzA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9q SHEATH

(Pseudomonas
aeruginosa) 		PF04984
(Phage_sheath_1)
PF17482
(Phage_sheath_1C) 		5 LEU A 128
VAL A 129
GLY A 132
SER A 201
LEU A 156
 None
 1.24A 4zbqA-3j9qA:
undetectable		 4zbqA-3j9qA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ju1 ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN

(Shewanella
oneidensis) 		PF16113
(ECH_2) 		5 VAL A 166
PHE A 105
LEU A  87
GLY A  82
LEU A 162
 None
FMT  A 403 (-2.8A)
None
FMT  A 403 ( 4.3A)
None
 1.34A 4zbqA-3ju1A:
0.9		 4zbqA-3ju1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l12 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE

(Ruegeria
pomeroyi) 		PF03009
(GDPD) 		5 LEU A 202
VAL A 183
PHE A  50
LEU A 128
LEU A 149
 None
 1.30A 4zbqA-3l12A:
undetectable		 4zbqA-3l12A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lu2 LMO2462 PROTEIN

(Listeria
monocytogenes) 		PF01244
(Peptidase_M19) 		5 LEU A 104
PHE A 153
LEU A 114
GLY A 154
LEU A 161
 None
 1.34A 4zbqA-3lu2A:
undetectable		 4zbqA-3lu2A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lvv GLUTAMATE--CYSTEINE
LIGASE

(Saccharomyces
cerevisiae) 		PF03074
(GCS) 		5 LEU A 489
VAL A 488
PHE A 271
GLY A  48
LEU A 267
 None
None
None
ADP  A 694 (-3.6A)
None
 1.34A 4zbqA-3lvvA:
undetectable		 4zbqA-3lvvA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n0l SERINE
HYDROXYMETHYLTRANSFE
RASE

(Campylobacter
jejuni) 		PF00464
(SHMT) 		5 PHE A 316
LEU A 383
GLY A 354
LEU A 357
SER A 376
 None
 1.22A 4zbqA-3n0lA:
2.1		 4zbqA-3n0lA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pz2 GERANYLGERANYL
TRANSFERASE TYPE-2
SUBUNIT BETA

(Rattus
norvegicus) 		PF00432
(Prenyltrans) 		5 LEU B  59
VAL B  56
LEU B  18
GLY B 277
SER B 299
 None
 1.35A 4zbqA-3pz2B:
undetectable		 4zbqA-3pz2B:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5k FALCILYSIN

(Plasmodium
falciparum) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF08367
(M16C_assoc) 		5 LEU A 871
VAL A 875
LEU A1075
SER A1012
SER A1008
 None
 1.33A 4zbqA-3s5kA:
undetectable		 4zbqA-3s5kA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3urh DIHYDROLIPOYL
DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 LEU A 188
VAL A 185
GLY A  45
LEU A  53
SER A 192
 None
None
FAD  A 500 (-3.4A)
None
None
 1.19A 4zbqA-3urhA:
undetectable		 4zbqA-3urhA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4buc UDP-N-ACETYLMURAMOYL
ALANINE--D-GLUTAMATE
LIGASE

(Thermotoga
maritima) 		PF08245
(Mur_ligase_M) 		5 LEU A 100
LEU A 108
GLY A  24
ARG A 104
SER A 103
 None
 1.21A 4zbqA-4bucA:
undetectable		 4zbqA-4bucA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fjo MITOTIC SPINDLE
ASSEMBLY CHECKPOINT
PROTEIN MAD2B

(Mus musculus) 		PF02301
(HORMA) 		5 LEU C  29
VAL C  25
PHE C 100
LEU C 201
SER C 131
 None
 1.30A 4zbqA-4fjoC:
undetectable		 4zbqA-4fjoC:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ha6 PYRIDOXINE 4-OXIDASE

(Mesorhizobium
loti) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		5 VAL A 491
LEU A 247
GLY A  24
SER A 272
LEU A 275
 None
None
FAD  A 601 (-3.2A)
None
FAD  A 601 ( 4.8A)
 1.27A 4zbqA-4ha6A:
2.5		 4zbqA-4ha6A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hyj RHODOPSIN

(Exiguobacterium
sibiricum) 		PF01036
(Bac_rhodopsin) 		5 LEU A  94
VAL A  95
LEU A 180
GLY A 102
LEU A 111
 None
 1.19A 4zbqA-4hyjA:
2.8		 4zbqA-4hyjA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jb7 ACCESSORY
COLONIZATION FACTOR
ACFC

(Vibrio cholerae) 		PF13531
(SBP_bac_11) 		5 LEU A 224
VAL A 223
PHE A 220
GLY A  76
LEU A  28
 None
 1.30A 4zbqA-4jb7A:
undetectable		 4zbqA-4jb7A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jb7 ACCESSORY
COLONIZATION FACTOR
ACFC

(Vibrio cholerae) 		PF13531
(SBP_bac_11) 		5 LEU A 224
VAL A 223
PHE A 220
LEU A  38
GLY A  76
 None
 1.03A 4zbqA-4jb7A:
undetectable		 4zbqA-4jb7A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k7g 3-HYDROXYPROLINE
DEHYDRATSE

(Agrobacterium
vitis) 		PF05544
(Pro_racemase) 		5 LEU B 142
VAL B 141
LEU B 264
GLY B 257
ARG B 306
 None
None
None
PYC  B 904 (-3.7A)
None
 1.12A 4zbqA-4k7gB:
undetectable		 4zbqA-4k7gB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n40 PROTEIN ECT2

(Homo sapiens) 		PF00533
(BRCT)
PF12738
(PTCB-BRCT) 		5 LEU A 150
VAL A 187
PHE A 155
LEU A 161
GLY A 154
 None
 1.33A 4zbqA-4n40A:
undetectable		 4zbqA-4n40A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0f SERINE PROTEASE
INHIBITOR 4, ISOFORM
B

(Drosophila
melanogaster) 		PF00079
(Serpin) 		5 VAL A 338
PHE A 108
LEU A 104
GLY A  50
ARG A 161
 None
 1.35A 4zbqA-4p0fA:
undetectable		 4zbqA-4p0fA:
21.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4po0 SERUM ALBUMIN

(Oryctolagus
cuniculus) 		PF00273
(Serum_albumin) 		10 LEU A 387
VAL A 388
ASN A 391
PHE A 403
LEU A 407
ARG A 410
GLY A 434
LEU A 453
ARG A 485
SER A 489
 NPS  A 601 ( 4.7A)
NPS  A 601 ( 3.7A)
NPS  A 601 (-4.3A)
None
NPS  A 601 ( 4.9A)
NPS  A 601 (-4.5A)
None
NPS  A 601 (-4.7A)
None
NPS  A 601 (-3.1A)
 0.71A 4zbqA-4po0A:
50.2		 4zbqA-4po0A:
71.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qtu PUTATIVE
METHYLTRANSFERASE
BUD23

(Saccharomyces
cerevisiae) 		PF08241
(Methyltransf_11) 		5 LEU B  60
LEU B  83
GLY B  75
LEU B  91
ARG B  89
 SAM  B 301 (-4.0A)
None
None
None
None
 1.26A 4zbqA-4qtuB:
undetectable		 4zbqA-4qtuB:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s2t PROTEIN APP-1

(Caenorhabditis
elegans) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
PF16188
(Peptidase_M24_C)
PF16189
(Creatinase_N_2) 		5 LEU P 446
VAL P 445
ASN P 442
PHE P 438
GLY P 532
 None
 1.00A 4zbqA-4s2tP:
undetectable		 4zbqA-4s2tP:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uw2 CSM1

(Thermococcus
onnurineus) 		PF01966
(HD) 		5 LEU A 745
VAL A 746
LEU A 705
GLY A 734
LEU A 741
 None
 0.94A 4zbqA-4uw2A:
undetectable		 4zbqA-4uw2A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4woe TAUROCYAMINE KINASE

(Schistosoma
mansoni) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		5 LEU A 579
VAL A 580
ARG A 484
GLY A 488
LEU A 606
 None
None
ADP  A 802 (-3.0A)
None
None
 0.93A 4zbqA-4woeA:
undetectable		 4zbqA-4woeA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xn3 TAIL SPIKE PROTEIN

(Salmonella
virus HK620) 		no annotation 5 VAL A 545
LEU A 559
GLY A 548
SER A 577
LEU A 576
 None
 1.11A 4zbqA-4xn3A:
undetectable		 4zbqA-4xn3A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yc7 FORMIN-LIKE PROTEIN
2

(Homo sapiens) 		PF06367
(Drf_FH3)
PF06371
(Drf_GBD) 		5 LEU B 140
VAL B 137
PHE B 125
LEU B 110
GLY B 132
 None
 1.36A 4zbqA-4yc7B:
undetectable		 4zbqA-4yc7B:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yhc STEROL REGULATORY
ELEMENT-BINDING
PROTEIN
CLEAVAGE-ACTIVATING
PROTEIN

(Schizosaccharomyces
pombe) 		no annotation 5 LEU A 631
VAL A 620
LEU A 642
GLY A 614
SER A 612
 None
 1.24A 4zbqA-4yhcA:
undetectable		 4zbqA-4yhcA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zu2 PUTATIVE
ISOHEXENYLGLUTACONYL
-COA HYDRATASE

(Pseudomonas
aeruginosa) 		PF00378
(ECH_1) 		5 VAL A 123
PHE A  64
LEU A  22
GLY A 117
LEU A  94
 None
 1.02A 4zbqA-4zu2A:
2.4		 4zbqA-4zu2A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a9t PUTATIVE
DEHYDROGENASE

(Amycolatopsis
orientalis) 		PF03446
(NAD_binding_2) 		5 LEU A  65
VAL A  67
LEU A  24
GLY A  17
SER A  62
 None
 1.30A 4zbqA-5a9tA:
undetectable		 4zbqA-5a9tA:
18.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus) 		PF00273
(Serum_albumin) 		7 ASN A 390
PHE A 402
ARG A 409
GLY A 430
LEU A 452
ARG A 484
SER A 488
 None
 1.34A 4zbqA-5dqfA:
55.7		 4zbqA-5dqfA:
99.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus) 		PF00273
(Serum_albumin) 		6 LEU A 386
ASN A 390
ARG A 409
GLY A 430
ARG A 484
SER A 488
 None
 1.12A 4zbqA-5dqfA:
55.7		 4zbqA-5dqfA:
99.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus) 		PF00273
(Serum_albumin) 		7 LEU A 386
VAL A 387
ASN A 390
ARG A 409
SER A 448
ARG A 484
SER A 488
 None
 0.66A 4zbqA-5dqfA:
55.7		 4zbqA-5dqfA:
99.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus) 		PF00273
(Serum_albumin) 		10 VAL A 387
ASN A 390
PHE A 402
LEU A 406
ARG A 409
GLY A 433
SER A 448
LEU A 452
ARG A 484
SER A 488
 None
 0.29A 4zbqA-5dqfA:
55.7		 4zbqA-5dqfA:
99.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ewu MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF02514
(CobN-Mg_chel) 		6 LEU A1030
VAL A1031
ASN A1085
PHE A1197
LEU A1201
SER A1227
 None
 1.48A 4zbqA-5ewuA:
undetectable		 4zbqA-5ewuA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eyt ADENYLOSUCCINATE
LYASE

(Schistosoma
mansoni) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		5 LEU A  36
PHE A 203
LEU A 217
GLY A 195
SER A 225
 None
 1.36A 4zbqA-5eytA:
undetectable		 4zbqA-5eytA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA

(Bacillus
thuringiensis) 		no annotation 5 LEU A 328
VAL A 324
LEU A 101
GLY A 318
SER A 108
 None
 1.17A 4zbqA-5gheA:
undetectable		 4zbqA-5gheA:
20.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus) 		PF00273
(Serum_albumin) 		5 LEU A  24
VAL A  25
PHE A  70
LEU A  74
GLY A 248
 None
 1.35A 4zbqA-5ghkA:
47.5		 4zbqA-5ghkA:
76.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus) 		PF00273
(Serum_albumin) 		6 LEU A 387
VAL A 388
ASN A 391
ARG A 410
ARG A 485
SER A 489
 None
 1.11A 4zbqA-5ghkA:
47.5		 4zbqA-5ghkA:
76.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus) 		PF00273
(Serum_albumin) 		5 LEU A 387
VAL A 388
LEU A 430
ARG A 485
SER A 489
 None
 1.33A 4zbqA-5ghkA:
47.5		 4zbqA-5ghkA:
76.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus) 		PF00273
(Serum_albumin) 		9 VAL A 388
ASN A 391
PHE A 403
LEU A 407
ARG A 410
GLY A 434
LEU A 453
ARG A 485
SER A 489
 None
 0.75A 4zbqA-5ghkA:
47.5		 4zbqA-5ghkA:
76.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gtm INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1

(Homo sapiens) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M)
PF02212
(GED) 		5 LEU A 323
VAL A 320
LEU A 111
GLY A  92
LEU A  87
 None
 1.13A 4zbqA-5gtmA:
2.8		 4zbqA-5gtmA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h64 SERINE/THREONINE-PRO
TEIN KINASE MTOR

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08771
(FRB_dom)
PF11865
(DUF3385) 		5 LEU A 869
VAL A 867
LEU A 891
GLY A 852
SER A 913
 None
 1.14A 4zbqA-5h64A:
undetectable		 4zbqA-5h64A:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ijx TYROSINE--TRNA
LIGASE,
MITOCHONDRIAL

(Coccidioides
posadasii) 		PF00579
(tRNA-synt_1b) 		5 VAL A  92
ASN A  93
LEU A 330
GLY A 283
LEU A 130
 None
 1.31A 4zbqA-5ijxA:
undetectable		 4zbqA-5ijxA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k7f TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Myxococcus
xanthus) 		PF00440
(TetR_N) 		5 LEU A 100
ASN A  97
PHE A 163
LEU A 138
LEU A  77
 None
 1.12A 4zbqA-5k7fA:
undetectable		 4zbqA-5k7fA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ko9 EMBRYONIC STEM
CELL-SPECIFIC
5-HYDROXYMETHYLCYTOS
INE-BINDING PROTEIN

(Homo sapiens) 		PF02586
(SRAP) 		5 LEU A 192
VAL A 191
PHE A  59
LEU A  54
SER A 194
 None
 1.30A 4zbqA-5ko9A:
undetectable		 4zbqA-5ko9A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mdx PHOTOSYSTEM II
PROTEIN D1

(Arabidopsis
thaliana) 		PF00124
(Photo_RC) 		5 LEU A 117
VAL A 116
LEU A  91
GLY A 171
LEU A 159
 CLA  A 405 ( 4.7A)
None
None
None
None
 1.30A 4zbqA-5mdxA:
undetectable		 4zbqA-5mdxA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o71 UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25

(Homo sapiens) 		no annotation 5 LEU A 597
VAL A 598
PHE A 395
LEU A 593
SER A 186
 None
 0.94A 4zbqA-5o71A:
undetectable		 4zbqA-5o71A:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5or7 CAPSID PROTEIN

(Norwalk virus) 		no annotation 5 LEU A 429
VAL A 428
PHE A 487
LEU A 253
ARG A 431
 None
 1.20A 4zbqA-5or7A:
undetectable		 4zbqA-5or7A:
7.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus) 		no annotation 7 ASN A 390
PHE A 402
LEU A 406
ARG A 409
GLY A 433
ARG A 484
SER A 488
 None
 0.80A 4zbqA-5oriA:
50.9		 4zbqA-5oriA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus) 		no annotation 7 ASN A 390
PHE A 402
LEU A 406
GLY A 433
LEU A 452
ARG A 484
SER A 488
 None
 0.75A 4zbqA-5oriA:
50.9		 4zbqA-5oriA:
75.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		5 VAL A 537
LEU A 545
GLY A 424
SER A 469
LEU A 499
 None
 1.35A 4zbqA-5tf0A:
undetectable		 4zbqA-5tf0A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfa NAD-REDUCING
HYDROGENASE

(Hydrogenophilus
thermoluteolus) 		PF00374
(NiFeSe_Hases) 		5 LEU D 165
VAL D 166
LEU D 204
ARG D 207
GLY D 118
 None
 1.28A 4zbqA-5xfaD:
undetectable		 4zbqA-5xfaD:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxo PERIPLASMIC
BETA-GLUCOSIDASE

(Bacteroides
thetaiotaomicron) 		no annotation 5 VAL A 535
LEU A 543
GLY A 422
SER A 467
LEU A 497
 None
 1.19A 4zbqA-5xxoA:
undetectable		 4zbqA-5xxoA:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3t RANBP-TYPE AND
C3HC4-TYPE ZINC
FINGER-CONTAINING
PROTEIN 1
SHARPIN

(Mus musculus) 		no annotation 5 LEU C 206
SER A  14
LEU A  13
ARG C 278
SER C 282
 None
 1.22A 4zbqA-5y3tC:
undetectable		 4zbqA-5y3tC:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus) 		no annotation 9 LEU A 387
VAL A 388
ASN A 391
PHE A 403
LEU A 407
GLY A 434
LEU A 453
ARG A 485
SER A 489
 None
 0.91A 4zbqA-5yxeA:
45.7		 4zbqA-5yxeA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus) 		no annotation 6 LEU A 387
VAL A 388
LEU A 430
GLY A 434
ARG A 485
SER A 489
 None
 1.43A 4zbqA-5yxeA:
45.7		 4zbqA-5yxeA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus) 		no annotation 6 VAL A 388
ASN A 391
PHE A 403
LEU A 407
ARG A 410
GLY A 434
 None
 0.90A 4zbqA-5yxeA:
45.7		 4zbqA-5yxeA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3y DENN
DOMAIN-CONTAINING
PROTEIN 3

(Mus musculus) 		no annotation 5 LEU A 918
VAL A 916
ASN A 915
PHE A 941
GLY A 896
 None
 1.24A 4zbqA-6b3yA:
undetectable		 4zbqA-6b3yA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c13 -

(-) 		no annotation 5 LEU A1124
VAL A1126
LEU A1032
GLY A1035
SER A1116
 None
 1.16A 4zbqA-6c13A:
undetectable		 4zbqA-6c13A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ftl RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN

(Skeletonema
marinoi) 		no annotation 5 VAL A 269
PHE A 203
LEU A 166
GLY A 241
SER A 266
 None
 1.12A 4zbqA-6ftlA:
undetectable		 4zbqA-6ftlA:
7.72