SIMILAR PATTERNS OF AMINO ACIDS FOR 4Z69_A_DIFA1007
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dwu | RIBOSOMAL PROTEIN L1 (Methanothermococcusthermolithotrophicus) |
PF00687(Ribosomal_L1) | 5 | ARG A 126LEU A 123LEU A 85ILE A 80ALA A 95 | None | 1.46A | 4z69A-1dwuA:0.3 | 4z69A-1dwuA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fui | L-FUCOSE ISOMERASE (Escherichiacoli) |
PF02952(Fucose_iso_C)PF07881(Fucose_iso_N1)PF07882(Fucose_iso_N2) | 5 | ARG A 494LEU A 491LEU A 379ILE A 387ALA A 370 | None | 1.35A | 4z69A-1fuiA:1.7 | 4z69A-1fuiA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gk2 | HISTIDINEAMMONIA-LYASE (Pseudomonasputida) |
PF00221(Lyase_aromatic) | 5 | ARG A 247LEU A 293LEU A 501ILE A 219ALA A 254 | None | 0.80A | 4z69A-1gk2A:2.4 | 4z69A-1gk2A:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hbx | ETS-DOMAIN PROTEINELK-4 (Homo sapiens) |
PF00178(Ets) | 5 | ARG G 43LEU G 44LEU G 11ILE G 24ALA G 38 | None | 1.36A | 4z69A-1hbxG:undetectable | 4z69A-1hbxG:12.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 6 | ARG A 218LEU A 219LEU A 260ILE A 264SER A 287ALA A 291 | CIT A2001 (-4.0A)NoneNoneNoneNoneCIT A2001 ( 3.9A) | 1.13A | 4z69A-1tf0A:37.7 | 4z69A-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 7 | LYS A 199TRP A 214LEU A 219LEU A 260ILE A 264SER A 287ALA A 291 | CIT A2001 ( 2.7A)NoneNoneNoneNoneNoneCIT A2001 ( 3.9A) | 0.64A | 4z69A-1tf0A:37.7 | 4z69A-1tf0A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v72 | ALDOLASE (Pseudomonasputida) |
PF01212(Beta_elim_lyase) | 5 | ARG A 127LEU A 126LEU A 176ILE A 147ALA A 164 | None | 1.19A | 4z69A-1v72A:0.0 | 4z69A-1v72A:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xng | NH(3)-DEPENDENTNAD(+) SYNTHETASE (Helicobacterpylori) |
PF02540(NAD_synthase) | 5 | ARG A 170LEU A 8LEU A 44ILE A 156ALA A 168 | None | 1.48A | 4z69A-1xngA:2.4 | 4z69A-1xngA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fjl | 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATEPHOSPHODIESTERASEGAMMA 1 (Rattusnorvegicus) |
PF00169(PH) | 5 | ARG A 144LEU A 24ILE A 29SER A 27ALA A 147 | None | 1.46A | 4z69A-2fjlA:undetectable | 4z69A-2fjlA:13.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jjm | GLYCOSYLTRANSFERASE, GROUP 1FAMILY PROTEIN (Bacillusanthracis) |
PF00534(Glycos_transf_1)PF13439(Glyco_transf_4) | 5 | LEU A 90LEU A 74ILE A 37SER A 76ALA A 79 | None | 1.36A | 4z69A-2jjmA:0.0 | 4z69A-2jjmA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kvc | PUTATIVEUNCHARACTERIZEDPROTEIN (Mycobacteriumtuberculosis) |
PF11829(DUF3349) | 5 | ARG A 37LEU A 93LEU A 15SER A 28ALA A 30 | None | 1.46A | 4z69A-2kvcA:undetectable | 4z69A-2kvcA:9.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nxx | ECDYSONE RECEPTOR(ECR, NRH1) (Triboliumcastaneum) |
PF00104(Hormone_recep) | 5 | ARG E 489LEU E 485LEU E 511SER E 509ALA E 505 | None | 1.30A | 4z69A-2nxxE:0.0 | 4z69A-2nxxE:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w38 | SIALIDASE (Pseudomonasaeruginosa) |
PF13088(BNR_2) | 5 | ARG A 260ARG A 198LEU A 255SER A 240ALA A 238 | None | 1.37A | 4z69A-2w38A:undetectable | 4z69A-2w38A:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ajb | PEROXISOMALBIOGENESIS FACTOR 19PEROXISOMALBIOGENESIS FACTOR 3 (Homo sapiens) |
PF04882(Peroxin-3)no annotation | 5 | LEU B 26LEU A 107ILE A 103SER A 88ALA A 91 | None | 1.38A | 4z69A-3ajbB:undetectable | 4z69A-3ajbB:7.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c0k | UPF0064 PROTEIN YCCW (Escherichiacoli) |
PF10672(Methyltrans_SAM) | 5 | LEU A 128LEU A 144ILE A 153SER A 142ALA A 138 | None | 1.48A | 4z69A-3c0kA:undetectable | 4z69A-3c0kA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fo5 | THIOESTERASE,ADIPOSE ASSOCIATED,ISOFORM BFIT2 (Homo sapiens) |
PF01852(START) | 5 | ARG A 447LEU A 508ILE A 506SER A 493ALA A 470 | None1PE A 2 (-4.7A)NoneNoneNone | 1.45A | 4z69A-3fo5A:undetectable | 4z69A-3fo5A:16.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hf9 | PROTEASOME (ALPHASUBUNIT) PRCA (Mycobacteriumtuberculosis) |
no annotation | 5 | ARG A 182LEU A 181ILE A 225SER A 228ALA A 232 | None | 1.36A | 4z69A-3hf9A:undetectable | 4z69A-3hf9A:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hhd | FATTY ACID SYNTHASE (Homo sapiens) |
PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | ARG A 515LEU A 566LEU A 797ILE A 800ALA A 814 | None | 1.30A | 4z69A-3hhdA:undetectable | 4z69A-3hhdA:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i1a | SPECTINOMYCINPHOSPHOTRANSFERASE (Legionellapneumophila) |
PF01636(APH) | 5 | ARG A 306LEU A 297ILE A 161SER A 176ALA A 172 | None | 1.50A | 4z69A-3i1aA:2.6 | 4z69A-3i1aA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3swd | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Escherichiacoli) |
PF00275(EPSP_synthase) | 5 | ARG A 103LEU A 100LEU A 56SER A 58ALA A 62 | None | 1.34A | 4z69A-3swdA:undetectable | 4z69A-3swdA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3toy | MANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY PROTEIN (Bradyrhizobiumsp. ORS 278) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | TRP A 349LEU A 345LEU A 272ILE A 278SER A 105 | None | 1.37A | 4z69A-3toyA:undetectable | 4z69A-3toyA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a3u | NADH:FLAVINOXIDOREDUCTASE/NADHOXIDASE (Zymomonasmobilis) |
PF00724(Oxidored_FMN) | 5 | LEU A 205LEU A 253ILE A 255SER A 251ALA A 247 | None | 1.22A | 4z69A-4a3uA:undetectable | 4z69A-4a3uA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dd5 | ACETYL-COAACETYLTRANSFERASE (Clostridioidesdifficile) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | ARG A 98LEU A 97LEU A 261ILE A 11ALA A 103 | None | 1.42A | 4z69A-4dd5A:undetectable | 4z69A-4dd5A:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dd5 | ACETYL-COAACETYLTRANSFERASE (Clostridioidesdifficile) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | ARG A 98LEU A 392LEU A 261ILE A 11ALA A 103 | None | 1.21A | 4z69A-4dd5A:undetectable | 4z69A-4dd5A:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fwv | TTC1975 PEPTIDASE (Meiothermustaiwanensis) |
PF13654(AAA_32) | 5 | ARG A 36LEU A 39LEU A 67ILE A 311ALA A 62 | None | 1.36A | 4z69A-4fwvA:3.1 | 4z69A-4fwvA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hbq | MUCOSAL ADDRESSINCELL ADHESIONMOLECULE 1 (Homo sapiens) |
PF09085(Adhes-Ig_like) | 5 | LEU A 129LEU A 103ILE A 199SER A 99ALA A 111 | None | 1.20A | 4z69A-4hbqA:undetectable | 4z69A-4hbqA:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4id0 | GLUTATHIONES-TRANSFERASE-LIKEPROTEIN YIBF (Pseudomonasfluorescens) |
PF13410(GST_C_2)PF13417(GST_N_3) | 5 | LEU A 184LEU A 100ILE A 104SER A 160ALA A 162 | None | 1.06A | 4z69A-4id0A:2.1 | 4z69A-4id0A:15.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ks9 | MALONYL-COADECARBOXYLASE (Cupriavidusmetallidurans) |
PF05292(MCD)PF17408(MCD_N) | 5 | TRP A 425LEU A 375LEU A 349ILE A 345ALA A 392 | None | 1.36A | 4z69A-4ks9A:undetectable | 4z69A-4ks9A:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lu1 | MAF-LIKE PROTEINYCEF (Escherichiacoli) |
PF02545(Maf) | 5 | ARG A 185LEU A 184LEU A 17ILE A 66ALA A 179 | None | 1.31A | 4z69A-4lu1A:undetectable | 4z69A-4lu1A:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o06 | PROBABLE 26SPROTEASOMEREGULATORY SUBUNITP27 (Saccharomycescerevisiae) |
PF00595(PDZ) | 5 | LEU A 213LEU A 186ILE A 160SER A 200ALA A 149 | NoneNoneNonePG4 A 301 (-2.9A)None | 1.30A | 4z69A-4o06A:undetectable | 4z69A-4o06A:10.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qik | ROQUIN-1 (Homo sapiens) |
no annotation | 5 | LEU A 381LEU A 360ILE A 363SER A 160ALA A 157 | NoneNoneNone A D 17 ( 4.1A)None | 1.47A | 4z69A-4qikA:2.7 | 4z69A-4qikA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tr2 | SUBTILISIN-LIKE 1SERINE PROTEASE (Plasmodiumvivax) |
PF00082(Peptidase_S8) | 5 | LEU A 170LEU A 186ILE A 193SER A 184ALA A 180 | None | 1.23A | 4z69A-4tr2A:undetectable | 4z69A-4tr2A:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wsb | POLYMERASE PB2 (Influenza Avirus) |
PF00604(Flu_PB2) | 5 | ARG C 299LEU C 298LEU C 280ILE C 266SER C 282 | None | 1.36A | 4z69A-4wsbC:undetectable | 4z69A-4wsbC:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wsi | MAGUK P55 SUBFAMILYMEMBER 5 (Homo sapiens) |
PF00595(PDZ)PF00625(Guanylate_kin)PF07653(SH3_2) | 5 | ARG A 498LEU A 499LEU A 484ILE A 595ALA A 651 | None | 1.47A | 4z69A-4wsiA:undetectable | 4z69A-4wsiA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zqg | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Moraxellacatarrhalis) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 5 | LYS A 143LEU A 244LEU A 163ILE A 181ALA A 173 | None | 1.46A | 4z69A-4zqgA:2.3 | 4z69A-4zqgA:20.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 5 | LEU A 218LEU A 259ILE A 263SER A 286ALA A 290 | NonePG4 A 602 ( 4.5A)NonePG4 A 602 (-3.9A)PG4 A 602 (-3.4A) | 0.56A | 4z69A-5dqfA:38.4 | 4z69A-5dqfA:76.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 5 | LYS A 198LEU A 259ILE A 263SER A 286ALA A 290 | PG4 A 602 ( 4.3A)PG4 A 602 ( 4.5A)NonePG4 A 602 (-3.9A)PG4 A 602 (-3.4A) | 0.94A | 4z69A-5dqfA:38.4 | 4z69A-5dqfA:76.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 5 | LYS A 198TRP A 213LEU A 259ILE A 263ALA A 290 | PG4 A 602 ( 4.3A)NonePG4 A 602 ( 4.5A)NonePG4 A 602 (-3.4A) | 1.17A | 4z69A-5dqfA:38.4 | 4z69A-5dqfA:76.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 5 | TRP A 213ARG A 217LEU A 218LEU A 259ILE A 263 | None CL A 617 ( 4.6A)NonePG4 A 602 ( 4.5A)None | 1.14A | 4z69A-5dqfA:38.4 | 4z69A-5dqfA:76.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 5 | TRP A 213LEU A 218LEU A 259ILE A 263ALA A 290 | NoneNonePG4 A 602 ( 4.5A)NonePG4 A 602 (-3.4A) | 0.79A | 4z69A-5dqfA:38.4 | 4z69A-5dqfA:76.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 6 | LYS A 199TRP A 214LEU A 219LEU A 260SER A 287ALA A 291 | None | 0.93A | 4z69A-5ghkA:36.3 | 4z69A-5ghkA:79.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 5 | TRP A 214ARG A 218LEU A 219LEU A 260ALA A 291 | None | 0.95A | 4z69A-5ghkA:36.3 | 4z69A-5ghkA:79.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzt | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 5 | LEU B1156LEU B1174ILE B1172SER B1134ALA B1078 | None | 1.17A | 4z69A-5gztB:undetectable | 4z69A-5gztB:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzu | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 5 | LEU A1156LEU A1174ILE A1172SER A1134ALA A1078 | None | 1.18A | 4z69A-5gzuA:undetectable | 4z69A-5gzuA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hmp | UNCONVENTIONALMYOSIN-VC (Homo sapiens) |
PF00063(Myosin_head) | 5 | ARG A 398LEU A 401LEU A 364ILE A 577SER A 366 | DMS A 805 (-3.4A)NoneNoneNoneNone | 1.24A | 4z69A-5hmpA:2.6 | 4z69A-5hmpA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jh5 | LYSINE-SPECIFICDEMETHYLASE 2B (Homo sapiens) |
PF00646(F-box) | 5 | ARG A1219LEU A1218LEU A1186ILE A1225ALA A1221 | None | 1.09A | 4z69A-5jh5A:undetectable | 4z69A-5jh5A:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kk5 | CRISPR-ASSOCIATEDENDONUCLEASE CPF1 (Acidaminococcussp. BV3L6) |
no annotation | 5 | ARG A 341LEU A 340LEU A 477SER A 473ALA A 449 | None | 1.44A | 4z69A-5kk5A:undetectable | 4z69A-5kk5A:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nkm | PROTEIN SMG-9 (Caenorhabditiselegans) |
no annotation | 5 | LEU D 319LEU D 102ILE D 312SER D 104ALA D 107 | None | 1.10A | 4z69A-5nkmD:undetectable | 4z69A-5nkmD:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nnb | ISATIN HYDROLASE A (Labrenziaaggregata) |
no annotation | 5 | LEU A 176ARG A 180LEU A 120ILE A 106ALA A 126 | None | 1.23A | 4z69A-5nnbA:undetectable | 4z69A-5nnbA:7.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opq | 3,6-ANHYDRO-D-GALACTOSIDASE (Zobelliagalactanivorans) |
no annotation | 5 | TRP A 226LEU A 275LEU A 541ILE A 252ALA A 174 | None | 1.16A | 4z69A-5opqA:undetectable | 4z69A-5opqA:10.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 5 | ARG A 198LEU A 259ILE A 263SER A 286ALA A 290 | None | 1.23A | 4z69A-5oriA:36.9 | 4z69A-5oriA:74.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 6 | LEU A 218ARG A 217LEU A 259ILE A 263SER A 286ALA A 290 | None | 1.46A | 4z69A-5oriA:36.9 | 4z69A-5oriA:74.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 6 | TRP A 213ARG A 217LEU A 218LEU A 259SER A 286ALA A 290 | None | 1.07A | 4z69A-5oriA:36.9 | 4z69A-5oriA:74.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u4n | FRUCTOSE-1 (Neisseriagonorrhoeae) |
PF01116(F_bP_aldolase) | 5 | ARG A 290LEU A 282ILE A 245SER A 284ALA A 287 | EDO A 404 (-3.1A)NoneNoneNoneNone | 1.40A | 4z69A-5u4nA:undetectable | 4z69A-5u4nA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uvd | NUCLEOTIDYLTRANSFERASE-LIKE PROTEIN (Paracoccidioidesbrasiliensis) |
no annotation | 5 | LEU A 196ARG A 200LEU A 144ILE A 171SER A 169 | None | 1.34A | 4z69A-5uvdA:undetectable | 4z69A-5uvdA:9.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x2o | TASTE RECEPTOR, TYPE1, MEMBER 3 (Oryzias latipes) |
PF01094(ANF_receptor) | 5 | TRP B 456LEU B 461ILE B 324SER B 301ALA B 298 | None | 1.38A | 4z69A-5x2oB:undetectable | 4z69A-5x2oB:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xtb | NADH-UBIQUINONEOXIDOREDUCTASE 75KDA SUBUNIT,MITOCHONDRIAL (Homo sapiens) |
PF00384(Molybdopterin)PF09326(NADH_dhqG_C)PF10588(NADH-G_4Fe-4S_3)PF13510(Fer2_4) | 5 | LEU M 401LEU M 452ILE M 455SER M 495ALA M 497 | None | 1.28A | 4z69A-5xtbM:undetectable | 4z69A-5xtbM:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 5 | LYS A 195LEU A 219LEU A 260ILE A 264SER A 287 | None | 1.20A | 4z69A-5yxeA:37.2 | 4z69A-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 5 | LYS A 199LEU A 219LEU A 260ILE A 264SER A 287 | None | 0.84A | 4z69A-5yxeA:37.2 | 4z69A-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b9x | HEPATITIS B VIRUS XINTERACTING PROTEINRAGULATOR COMPLEXPROTEIN LAMTOR4 (Homo sapiens) |
no annotation | 5 | LEU D 55LEU E 130ILE E 158SER E 128ALA E 124 | None | 1.15A | 4z69A-6b9xD:undetectable | 4z69A-6b9xD:10.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d9y | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Paraburkholderiaphymatum) |
no annotation | 5 | ARG A 30LEU A 29LEU A 37ILE A 13ALA A 23 | None | 1.41A | 4z69A-6d9yA:undetectable | 4z69A-6d9yA:9.79 |