SIMILAR PATTERNS OF AMINO ACIDS FOR 4Z4F_A_IPHA902_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bxk | PROTEIN(DTDP-GLUCOSE4,6-DEHYDRATASE) (Escherichiacoli) |
PF16363(GDP_Man_Dehyd) | 4 | LYS A 277PRO A 278LEU A 270GLU A 271 | None | 1.04A | 4z4fA-1bxkA:2.3 | 4z4fA-1bxkA:16.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cli | PROTEIN(PHOSPHORIBOSYL-AMINOIMIDAZOLESYNTHETASE) (Escherichiacoli) |
PF00586(AIRS)PF02769(AIRS_C) | 4 | LEU A 222PRO A 189LEU A 73TYR A 194 | None | 1.02A | 4z4fA-1cliA:2.0 | 4z4fA-1cliA:16.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ebd | DIHYDROLIPOAMIDEDEHYDROGENASE (Geobacillusstearothermophilus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | LEU A 170PRO A 54LEU A 191GLU A 190 | None | 1.07A | 4z4fA-1ebdA:undetectable | 4z4fA-1ebdA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fp9 | 4-ALPHA-GLUCANOTRANSFERASE (Thermusthermophilus) |
PF02446(Glyco_hydro_77) | 4 | LEU A 438PRO A 378LEU A 418TYR A 417 | None | 0.99A | 4z4fA-1fp9A:undetectable | 4z4fA-1fp9A:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1guz | MALATE DEHYDROGENASE (Chlorobaculumtepidum;Prosthecochlorisvibrioformis) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | LEU A 171PRO A 267LEU A 291TYR A 257 | None | 1.07A | 4z4fA-1guzA:undetectable | 4z4fA-1guzA:15.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gv0 | MALATE DEHYDROGENASE (Chlorobaculumtepidum) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | LEU A 171PRO A 267LEU A 291TYR A 257 | None | 1.06A | 4z4fA-1gv0A:undetectable | 4z4fA-1gv0A:16.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hcy | ARTHROPODANHEMOCYANIN (Panulirusinterruptus) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 4 | LEU A 18PRO A 135LEU A 119TYR A 120 | None | 0.97A | 4z4fA-1hcyA:0.0 | 4z4fA-1hcyA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jig | DLP-2 (Bacillusanthracis) |
PF00210(Ferritin) | 4 | LEU A 21TYR A 54LEU A 105TYR A 102 | None | 1.04A | 4z4fA-1jigA:undetectable | 4z4fA-1jigA:10.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1knb | ADENOVIRUS TYPE 5FIBER PROTEIN (HumanmastadenovirusC) |
PF00541(Adeno_knob) | 4 | LYS A 528PRO A 529GLU A 566TYR A 563 | None | 0.86A | 4z4fA-1knbA:undetectable | 4z4fA-1knbA:11.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m3u | 3-METHYL-2-OXOBUTANOATEHYDROXYMETHYLTRANSFERASE (Escherichiacoli) |
PF02548(Pantoate_transf) | 4 | LEU A 213LYS A 231GLU A 250TYR A 256 | None | 0.93A | 4z4fA-1m3uA:undetectable | 4z4fA-1m3uA:14.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ni6 | HEME OXYGENASE 1 (Homo sapiens) |
PF01126(Heme_oxygenase) | 4 | LEU A 49PRO A 106LEU A 217GLU A 216 | None | 1.05A | 4z4fA-1ni6A:undetectable | 4z4fA-1ni6A:13.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pvm | CONSERVEDHYPOTHETICAL PROTEINTA0289 (Thermoplasmaacidophilum) |
PF00571(CBS)PF09151(DUF1936) | 4 | LEU A 100PRO A 80LEU A 95TYR A 94 | None | 0.85A | 4z4fA-1pvmA:undetectable | 4z4fA-1pvmA:11.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qhv | PROTEIN (ADENOVIRUSFIBRE) (HumanmastadenovirusC) |
PF00541(Adeno_knob) | 4 | LYS A 528PRO A 529GLU A 567TYR A 564 | None | 0.96A | 4z4fA-1qhvA:undetectable | 4z4fA-1qhvA:11.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qiu | ADENOVIRUS FIBRE (HumanmastadenovirusC) |
PF00541(Adeno_knob)PF00608(Adeno_shaft) | 4 | LYS A 528PRO A 529GLU A 567TYR A 564 | None | 0.98A | 4z4fA-1qiuA:undetectable | 4z4fA-1qiuA:16.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tt4 | PUTATIVE CYTOPLASMICPROTEIN (Salmonellaenterica) |
PF04107(GCS2) | 4 | LEU A 264PRO A 269LEU A 150TYR A 149 | None | 1.06A | 4z4fA-1tt4A:undetectable | 4z4fA-1tt4A:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xi8 | MOLYBDENUM COFACTORBIOSYNTHESIS PROTEIN (Pyrococcusfuriosus) |
PF00994(MoCF_biosynth)PF03453(MoeA_N)PF03454(MoeA_C) | 4 | LEU A 315LYS A 182PRO A 183GLU A 221 | None | 0.91A | 4z4fA-1xi8A:4.6 | 4z4fA-1xi8A:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z1w | TRICORN PROTEASEINTERACTING FACTORF3 (Thermoplasmaacidophilum) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 4 | LEU A 461LYS A 401PRO A 402TYR A 364 | None | 0.86A | 4z4fA-1z1wA:3.8 | 4z4fA-1z1wA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zk7 | MERCURIC REDUCTASE (Pseudomonasaeruginosa) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | LEU A 170PRO A 49LEU A 191GLU A 190 | NoneNoneNoneFAD A 666 ( 4.7A) | 1.07A | 4z4fA-1zk7A:undetectable | 4z4fA-1zk7A:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dh4 | YPL069C (Saccharomycescerevisiae) |
PF00348(polyprenyl_synt) | 4 | TYR A 216LYS A 220LEU A 283GLU A 284 | None | 0.95A | 4z4fA-2dh4A:undetectable | 4z4fA-2dh4A:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2erq | VASCULARAPOPTOSIS-INDUCINGPROTEIN 1 (Crotalus atrox) |
PF00200(Disintegrin)PF01421(Reprolysin)PF08516(ADAM_CR) | 4 | LEU A 383PRO A 388LEU A 195TYR A 194 | None | 0.93A | 4z4fA-2erqA:4.3 | 4z4fA-2erqA:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2esf | CARBONIC ANHYDRASE 2 (Escherichiacoli) |
PF00484(Pro_CA) | 4 | LEU A 134LYS A 129LEU A 149GLU A 153 | None | 1.06A | 4z4fA-2esfA:3.6 | 4z4fA-2esfA:12.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g1s | RENIN (Homo sapiens) |
PF00026(Asp) | 4 | LEU A 241PRO A 261LEU A 293TYR A 279 | None | 0.72A | 4z4fA-2g1sA:undetectable | 4z4fA-2g1sA:16.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hq4 | HYPOTHETICAL PROTEINPH1570 (Pyrococcushorikoshii) |
PF09638(Ph1570) | 4 | LEU A 35TYR A 39LEU A 65GLU A 66 | None | 0.95A | 4z4fA-2hq4A:undetectable | 4z4fA-2hq4A:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jjf | L-LYSINE EPSILONAMINOTRANSFERASE (Mycobacteriumtuberculosis) |
PF00202(Aminotran_3) | 4 | LEU A 335LYS A 92PRO A 93GLU A 126 | None | 0.93A | 4z4fA-2jjfA:2.8 | 4z4fA-2jjfA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mbm | TOP7 FOLD PROTEINTOP7M13 (syntheticconstruct) |
no annotation | 4 | LEU A 25TYR A 26LEU A 33GLU A 32 | None | 0.83A | 4z4fA-2mbmA:undetectable | 4z4fA-2mbmA:10.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mf4 | HYBRID POLYKETIDESYNTHASE-NONRIBOSOMAL PEPTIDESYNTHETASE (Streptomycesvirginiae) |
PF00550(PP-binding) | 4 | LEU A6750TYR A6751LEU A6772GLU A6775 | None | 1.02A | 4z4fA-2mf4A:2.1 | 4z4fA-2mf4A:8.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qae | DIHYDROLIPOYLDEHYDROGENASE (Trypanosomacruzi) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | LEU A 168PRO A 48LEU A 189GLU A 188 | None | 1.03A | 4z4fA-2qaeA:undetectable | 4z4fA-2qaeA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v4j | SULFITE REDUCTASE,DISSIMILATORY-TYPESUBUNIT BETASULFITE REDUCTASE,DISSIMILATORY-TYPESUBUNIT GAMMA (Desulfovibriovulgaris;Desulfovibriovulgaris) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr)PF04358(DsrC) | 4 | LEU C 53TYR C 56LEU C 98GLU B 223 | None | 1.02A | 4z4fA-2v4jC:undetectable | 4z4fA-2v4jC:8.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzs | PUTATIVEALPHA-1,2-MANNOSIDASE (Bacteroidesthetaiotaomicron) |
PF07971(Glyco_hydro_92) | 4 | LEU A 372TYR A 376PRO A 383LEU A 403 | None | 0.85A | 4z4fA-2wzsA:undetectable | 4z4fA-2wzsA:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x1i | 4-ALPHA-GLUCANOTRANSFERASE (Thermusbrockianus) |
PF02446(Glyco_hydro_77) | 4 | LEU A 438PRO A 378LEU A 418TYR A 417 | None | 0.92A | 4z4fA-2x1iA:undetectable | 4z4fA-2x1iA:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z3k | LEUCYL/PHENYLALANYL-TRNA-PROTEINTRANSFERASE (Escherichiacoli) |
PF03588(Leu_Phe_trans) | 4 | LEU A 38PRO A 48LEU A 123TYR A 120 | None | 0.98A | 4z4fA-2z3kA:undetectable | 4z4fA-2z3kA:15.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zc0 | ALANINE GLYOXYLATETRANSAMINASE (Thermococcuslitoralis) |
PF00155(Aminotran_1_2) | 4 | LYS A 330PRO A 331LEU A 319GLU A 320 | None | 0.80A | 4z4fA-2zc0A:2.3 | 4z4fA-2zc0A:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3adr | PUTATIVEUNCHARACTERIZEDPROTEIN ST1585 (Sulfurisphaeratokodaii) |
PF00753(Lactamase_B) | 4 | LEU A 142TYR A 144LYS A 81GLU A 128 | None | 1.07A | 4z4fA-3adrA:undetectable | 4z4fA-3adrA:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cvd | PLASTOCYANIN (Phormidiumlaminosum) |
PF00127(Copper-bind) | 4 | LEU A 55PRO A 81LEU A 59TYR A 85 | None | 1.06A | 4z4fA-3cvdA:undetectable | 4z4fA-3cvdA:11.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ffr | PHOSPHOSERINEAMINOTRANSFERASESERC (Cytophagahutchinsonii) |
PF00266(Aminotran_5) | 4 | LEU A 171PRO A 174LEU A 55GLU A 56 | None | 1.02A | 4z4fA-3ffrA:undetectable | 4z4fA-3ffrA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgt | PUTATIVEPHOSPHOLIPASE B-LIKE2 40 KDA FORM (Mus musculus) |
PF04916(Phospholip_B) | 4 | LEU B 255TYR B 427LEU B 422GLU B 421 | None | 0.98A | 4z4fA-3fgtB:undetectable | 4z4fA-3fgtB:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3glq | ADENOSYLHOMOCYSTEINASE (Burkholderiapseudomallei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | TYR A 425LEU A 207GLU A 211TYR A 208 | None | 1.04A | 4z4fA-3glqA:undetectable | 4z4fA-3glqA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h11 | CASP8 AND FADD-LIKEAPOPTOSIS REGULATOR (Homo sapiens) |
PF00656(Peptidase_C14) | 4 | LEU A 477TYR A 479LEU A 274TYR A 276 | None | 1.07A | 4z4fA-3h11A:4.2 | 4z4fA-3h11A:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jr7 | UNCHARACTERIZED EGVFAMILY PROTEINCOG1307 ([Ruminococcus]gnavus) |
PF02645(DegV) | 4 | LEU A 183LYS A 206PRO A 207GLU A 181 | None | 0.79A | 4z4fA-3jr7A:undetectable | 4z4fA-3jr7A:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lad | DIHYDROLIPOAMIDEDEHYDROGENASE (Azotobactervinelandii) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | LEU A 174PRO A 55LEU A 195GLU A 194 | None | 0.98A | 4z4fA-3ladA:undetectable | 4z4fA-3ladA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ldr | FRUCTOSYLTRANSFERASE (Aspergillusjaponicus) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 4 | PRO A 28LEU A 534GLU A 535TYR A 619 | None | 1.05A | 4z4fA-3ldrA:undetectable | 4z4fA-3ldrA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lwu | SUCCINYLGLUTAMATEDESUCCINYLASE/ASPARTOACYLASE (Shewanellafrigidimarina) |
PF04952(AstE_AspA) | 4 | LEU A 288TYR A 287PRO A 204LEU A 201 | None | 0.91A | 4z4fA-3lwuA:2.1 | 4z4fA-3lwuA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mwc | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Kosmotogaolearia) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 249PRO A 237LEU A 217GLU A 216 | None | 0.79A | 4z4fA-3mwcA:undetectable | 4z4fA-3mwcA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oad | RENIN (Homo sapiens) |
PF00026(Asp) | 4 | LEU B 246PRO B 266LEU B 298TYR B 284 | None | 0.68A | 4z4fA-3oadB:undetectable | 4z4fA-3oadB:10.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p4e | PHOSPHORIBOSYLFORMYLGLYCINAMIDINECYCLO-LIGASE (Vibrio cholerae) |
PF00586(AIRS)PF02769(AIRS_C) | 4 | LEU A 222PRO A 190LEU A 74TYR A 195 | None | 1.01A | 4z4fA-3p4eA:undetectable | 4z4fA-3p4eA:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qr1 | PHOSPHOLIPASE C-BETA(PLC-BETA) (Doryteuthispealeii) |
PF00168(C2)PF00387(PI-PLC-Y)PF00388(PI-PLC-X)PF09279(EF-hand_like) | 4 | LEU A 303TYR A 304LEU A 223TYR A 222 | None | 0.81A | 4z4fA-3qr1A:undetectable | 4z4fA-3qr1A:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT M (Escherichiacoli) |
no annotation | 4 | LEU M 244LYS M 234PRO M 236LEU M 259 | None | 0.98A | 4z4fA-3rkoM:undetectable | 4z4fA-3rkoM:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tad | LIPRIN-ALPHA-2 (Homo sapiens) |
PF00536(SAM_1)PF07647(SAM_2) | 4 | LEU A 909TYR A1016LEU A 885GLU A 886 | None | 0.89A | 4z4fA-3tadA:undetectable | 4z4fA-3tadA:16.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tl2 | MALATE DEHYDROGENASE (Bacillusanthracis) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | LEU A 177PRO A 273LEU A 297TYR A 263 | None | 1.01A | 4z4fA-3tl2A:2.4 | 4z4fA-3tl2A:16.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tos | CALS11 (Micromonosporaechinospora) |
PF05711(TylF) | 4 | TYR A 193PRO A 195LEU A 200GLU A 201 | NoneSAH A 258 (-4.1A)NoneNone | 0.99A | 4z4fA-3tosA:undetectable | 4z4fA-3tosA:15.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3urh | DIHYDROLIPOYLDEHYDROGENASE (Sinorhizobiummeliloti) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | LEU A 169PRO A 48LEU A 190GLU A 189 | NoneNoneNoneFAD A 500 ( 4.5A) | 1.07A | 4z4fA-3urhA:undetectable | 4z4fA-3urhA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wg6 | CONJUGATEDPOLYKETONE REDUCTASEC1 (Candidaparapsilosis) |
PF00248(Aldo_ket_red) | 4 | LEU A 145TYR A 104PRO A 103TYR A 122 | None | 1.06A | 4z4fA-3wg6A:undetectable | 4z4fA-3wg6A:15.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zzf | ACETYLGLUTAMATEKINASE (Saccharomycescerevisiae) |
PF00696(AA_kinase) | 4 | LEU A 120TYR A 124PRO A 130LEU A 183 | None | 0.99A | 4z4fA-3zzfA:undetectable | 4z4fA-3zzfA:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zzi | ACETYLGLUTAMATEKINASE (Saccharomycescerevisiae) |
PF00696(AA_kinase)PF04768(NAT) | 4 | LEU A 120TYR A 124PRO A 130LEU A 183 | None | 1.04A | 4z4fA-3zziA:3.4 | 4z4fA-3zziA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4as3 | PHOSPHORYLCHOLINEPHOSPHATASE (Pseudomonasaeruginosa) |
no annotation | 4 | LEU A 60LEU A 79GLU A 77TYR A 82 | None | 1.01A | 4z4fA-4as3A:2.3 | 4z4fA-4as3A:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e2o | ALPHA-AMYLASE (Geobacillusthermoleovorans) |
PF00128(Alpha-amylase) | 4 | LEU A 476PRO A 441LEU A 446TYR A 462 | None | 1.01A | 4z4fA-4e2oA:2.0 | 4z4fA-4e2oA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eq5 | DNA LIGASE (Thermococcussibiricus) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 4 | LEU A 405PRO A 435GLU A 398TYR A 401 | None | 0.89A | 4z4fA-4eq5A:undetectable | 4z4fA-4eq5A:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4erc | DUAL SPECIFICITYPROTEIN PHOSPHATASE23 (Homo sapiens) |
PF00782(DSPc) | 4 | LEU A 39PRO A 47LEU A 56TYR A 28 | None | 1.06A | 4z4fA-4ercA:2.6 | 4z4fA-4ercA:10.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f1n | KPAGO (Vanderwaltozymapolyspora) |
PF02171(Piwi) | 4 | LEU A1026PRO A1038LEU A1075TYR A1081 | None | 1.00A | 4z4fA-4f1nA:36.9 | 4z4fA-4f1nA:27.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fek | PUTATIVE DIFLAVINFLAVOPROTEIN A 5 (Nostoc sp. PCC7120) |
no annotation | 4 | LEU A 99PRO A 58LEU A 68TYR A 67 | None | 0.88A | 4z4fA-4fekA:undetectable | 4z4fA-4fekA:14.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g3a | CLIP-ASSOCIATINGPROTEIN (Drosophilamelanogaster) |
PF12348(CLASP_N) | 4 | LEU A 192TYR A 196LEU A 221GLU A 222 | None | 0.98A | 4z4fA-4g3aA:undetectable | 4z4fA-4g3aA:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gn2 | OXACILLINASE (Pseudomonasaeruginosa) |
PF00905(Transpeptidase) | 4 | LEU A 79PRO A 105LEU A 120TYR A 116 | None | 0.99A | 4z4fA-4gn2A:undetectable | 4z4fA-4gn2A:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4guz | PROBABLE ARYLAMINEN-ACETYL TRANSFERASE (Mycobacteroidesabscessus) |
PF00797(Acetyltransf_2) | 4 | LEU A 29PRO A 135LEU A 117GLU A 120 | None | 0.83A | 4z4fA-4guzA:undetectable | 4z4fA-4guzA:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ikh | GLUTATHIONES-TRANSFERASE (Pseudomonasprotegens) |
PF00043(GST_C)PF02798(GST_N) | 4 | LEU A 23PRO A 231LEU A 38GLU A 39 | None | 0.96A | 4z4fA-4ikhA:undetectable | 4z4fA-4ikhA:15.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4js5 | EXODEOXYRIBONUCLEASEI (Escherichiacoli) |
PF00929(RNase_T)PF08411(Exonuc_X-T_C) | 4 | LEU A 467PRO A 59LEU A 447GLU A 446 | None | 0.99A | 4z4fA-4js5A:undetectable | 4z4fA-4js5A:20.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4krf | PROTEIN ARGONAUTE-1 (Homo sapiens) |
PF02170(PAZ)PF02171(Piwi)PF08699(ArgoL1)PF16486(ArgoN)PF16487(ArgoMid)PF16488(ArgoL2) | 5 | LEU A 648TYR A 652PRO A 659LEU A 692TYR A 696 | None | 0.35A | 4z4fA-4krfA:61.7 | 4z4fA-4krfA:82.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lcc | BETA-2-MICROGLOBULIN, MHC CLASSI-RELATED PROTEIN (Bos taurus) |
PF00129(MHC_I)PF07654(C1-set) | 4 | LEU C 64TYR C 28PRO C 345TYR C 10 | None | 0.90A | 4z4fA-4lccC:undetectable | 4z4fA-4lccC:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mf6 | GLUTATHIONES-TRANSFERASE DOMAIN (Paraburkholderiagraminis) |
PF00043(GST_C)PF02798(GST_N) | 4 | LEU A 23PRO A 231LEU A 38GLU A 39 | None | 0.78A | 4z4fA-4mf6A:undetectable | 4z4fA-4mf6A:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n78 | CYTOPLASMICFMR1-INTERACTINGPROTEIN 1 (Homo sapiens) |
PF05994(FragX_IP)PF07159(DUF1394) | 5 | LEU A 852TYR A 855PRO A 853LEU A 847GLU A 846 | None | 1.47A | 4z4fA-4n78A:undetectable | 4z4fA-4n78A:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nax | GLUTATHIONES-TRANSFERASE,N-TERMINAL DOMAINPROTEIN (Pseudomonasputida) |
PF00043(GST_C)PF02798(GST_N) | 4 | LEU A 23PRO A 230LEU A 38GLU A 39 | None | 0.90A | 4z4fA-4naxA:undetectable | 4z4fA-4naxA:15.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nhz | PUTATIVE GLUTATHIONES-TRANSFERASE ENZYMEWITHTHIOREDOXIN-LIKEDOMAIN (Bradyrhizobiumsp. BTAi1) |
PF00043(GST_C)PF02798(GST_N) | 4 | LEU A 23PRO A 231LEU A 38GLU A 39 | None | 0.90A | 4z4fA-4nhzA:undetectable | 4z4fA-4nhzA:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pmn | TAT-SECRETED PROTEINRV2525C (Mycobacteriumtuberculosis) |
PF08924(DUF1906) | 4 | LEU A 127TYR A 65LYS A 79PRO A 80 | GOL A 302 (-4.9A)NoneMES A 301 (-2.7A)None | 1.05A | 4z4fA-4pmnA:undetectable | 4z4fA-4pmnA:13.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pmr | TAT-SECRETED PROTEINRV2525C (Mycobacteriumtuberculosis) |
PF08924(DUF1906) | 4 | LEU A 127TYR A 65LYS A 79PRO A 80 | NoneNoneEPE A 301 (-2.8A)None | 1.05A | 4z4fA-4pmrA:2.4 | 4z4fA-4pmrA:12.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u7l | LEUCINE-RICH REPEATSANDIMMUNOGLOBULIN-LIKEDOMAINS PROTEIN 1 (Homo sapiens) |
PF01463(LRRCT)PF13855(LRR_8) | 4 | LEU A 80PRO A 68LEU A 101TYR A 98 | None | 0.97A | 4z4fA-4u7lA:undetectable | 4z4fA-4u7lA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u8h | CRYPTOCHROME-2 (Mus musculus) |
PF00875(DNA_photolyase)PF03441(FAD_binding_7) | 4 | LEU A 290TYR A 291LYS A 295GLU A 253 | None | 1.04A | 4z4fA-4u8hA:2.9 | 4z4fA-4u8hA:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xdy | KETOL-ACIDREDUCTOISOMERASE (unculturedarchaeonGZfos26G2) |
PF01450(IlvC)PF07991(IlvN) | 4 | LEU A 102PRO A 124GLU A 95TYR A 94 | None | 0.99A | 4z4fA-4xdyA:undetectable | 4z4fA-4xdyA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zyj | DNMZ (Streptomycespeucetius) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | LEU A 88LYS A 22PRO A 21LEU A 18 | None | 0.97A | 4z4fA-4zyjA:undetectable | 4z4fA-4zyjA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a4j | FORMATE--TETRAHYDROFOLATE LIGASE (Tepidanaerobacteracetatoxydans) |
PF01268(FTHFS) | 4 | TYR A 44LYS A 255PRO A 256GLU A 33 | EDO A1562 (-4.5A)EDO A1562 (-3.2A)NoneNone | 0.70A | 4z4fA-5a4jA:6.5 | 4z4fA-5a4jA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cs0 | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF08326(ACC_central) | 4 | LEU A 838TYR A 840LEU A 918TYR A 914 | None | 0.95A | 4z4fA-5cs0A:undetectable | 4z4fA-5cs0A:14.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5csa | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF00364(Biotin_lipoyl)PF08326(ACC_central) | 4 | LEU A 838TYR A 840LEU A 918TYR A 914 | None | 1.04A | 4z4fA-5csaA:2.3 | 4z4fA-5csaA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5csl | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF00289(Biotin_carb_N)PF00364(Biotin_lipoyl)PF01039(Carboxyl_trans)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2)PF08326(ACC_central) | 4 | LEU A 838TYR A 840LEU A 918TYR A 914 | None | 1.06A | 4z4fA-5cslA:3.4 | 4z4fA-5cslA:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gnb | SPIKE GLYCOPROTEIN (HumancoronavirusHKU1) |
PF09408(Spike_rec_bind) | 4 | LEU A 409TYR A 414PRO A 341LEU A 401 | None | 1.05A | 4z4fA-5gnbA:undetectable | 4z4fA-5gnbA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gvs | PROBABLEATP-DEPENDENT RNAHELICASE DDX41 (Homo sapiens) |
PF00270(DEAD) | 4 | LEU A 284PRO A 189LEU A 244GLU A 245 | None | 0.91A | 4z4fA-5gvsA:undetectable | 4z4fA-5gvsA:13.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h67 | CHROMOSOME PARTITIONPROTEIN SMCCHROMOSOME PARTITIONPROTEIN SMC (Bacillussubtilis;Bacillussubtilis) |
PF02463(SMC_N)PF02463(SMC_N) | 4 | LEU B1004LYS B 999LEU A 195GLU A 199 | None | 0.94A | 4z4fA-5h67B:undetectable | 4z4fA-5h67B:11.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ikz | OXALATE BIOSYNTHETICCOMPONENT 1 (Burkholderiathailandensis) |
PF05853(BKACE) | 4 | LEU A 729LYS A 680PRO A 681GLU A 688 | None | 0.75A | 4z4fA-5ikzA:undetectable | 4z4fA-5ikzA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j6q | CELL WALL BINDINGPROTEIN CWP8 (Clostridioidesdifficile) |
PF04122(CW_binding_2) | 4 | LEU A 223TYR A 221LYS A 216GLU A 261 | None | 0.90A | 4z4fA-5j6qA:undetectable | 4z4fA-5j6qA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxm | PRIB (Streptomycessp. RM-5-8) |
PF11991(Trp_DMAT) | 4 | LEU A 35PRO A 81LEU A 76TYR A 386 | None | 0.99A | 4z4fA-5jxmA:undetectable | 4z4fA-5jxmA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k04 | UNCHARACTERIZEDPROTEIN (Candidaalbicans) |
PF09797(NatB_MDM20) | 4 | LEU A 406TYR A 404LEU A 372GLU A 369 | None | 1.02A | 4z4fA-5k04A:undetectable | 4z4fA-5k04A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tr3 | DIHYDROLIPOYLDEHYDROGENASE (Pseudomonasputida) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | LEU A 175PRO A 56LEU A 196GLU A 195 | NoneNoneNoneFAD A 501 ( 4.6A) | 1.04A | 4z4fA-5tr3A:undetectable | 4z4fA-5tr3A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v0i | TRYPTOPHAN--TRNALIGASE (Escherichiacoli) |
PF00579(tRNA-synt_1b) | 4 | LEU A 16TYR A 21LEU A 66TYR A 67 | None | 0.56A | 4z4fA-5v0iA:undetectable | 4z4fA-5v0iA:17.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vm9 | PROTEIN ARGONAUTE-3 (Homo sapiens) |
no annotation | 7 | LEU A 651TYR A 655LYS A 661PRO A 662LEU A 695GLU A 696TYR A 699 | None | 0.81A | 4z4fA-5vm9A:58.0 | 4z4fA-5vm9A:79.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5wea | PROTEIN ARGONAUTE-2 (Homo sapiens) |
no annotation | 6 | LEU A 650LYS A 660PRO A 661LEU A 694GLU A 695TYR A 698 | IPH A 901 (-4.7A)NoneNoneIPH A 901 (-3.9A)IPH A 901 (-3.6A)IPH A 901 ( 4.9A) | 0.91A | 4z4fA-5weaA:57.4 | 4z4fA-5weaA:99.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5wea | PROTEIN ARGONAUTE-2 (Homo sapiens) |
no annotation | 6 | LEU A 650TYR A 654PRO A 661LEU A 694GLU A 695TYR A 698 | IPH A 901 (-4.7A)NoneNoneIPH A 901 (-3.9A)IPH A 901 (-3.6A)IPH A 901 ( 4.9A) | 0.65A | 4z4fA-5weaA:57.4 | 4z4fA-5weaA:99.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x1y | MERCURIC REDUCTASE (Lysinibacillussphaericus) |
no annotation | 4 | LEU B 243PRO B 129LEU B 264GLU B 263 | NoneNoneFAD B 601 ( 4.9A)FAD B 601 ( 4.5A) | 1.01A | 4z4fA-5x1yB:undetectable | 4z4fA-5x1yB:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x62 | CARNOSINEN-METHYLTRANSFERASE (Saccharomycescerevisiae) |
PF07942(N2227) | 4 | LEU A 368TYR A 385PRO A 383GLU A 120 | None | 0.88A | 4z4fA-5x62A:undetectable | 4z4fA-5x62A:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bz0 | DIHYDROLIPOYLDEHYDROGENASE (Acinetobacterbaumannii) |
no annotation | 4 | LEU A 174PRO A 55LEU A 195GLU A 194 | NoneNoneNoneFAD A 501 ( 4.5A) | 1.03A | 4z4fA-6bz0A:undetectable | 4z4fA-6bz0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d0n | CLC-TYPEFLUORIDE/PROTONANTIPORTER (Enterococcuscasseliflavus) |
no annotation | 4 | LEU A 145LYS A 140LEU A 17GLU A 13 | NoneNoneDMU A 501 ( 4.8A)None | 1.02A | 4z4fA-6d0nA:undetectable | 4z4fA-6d0nA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dfu | TRYPTOPHAN--TRNALIGASE (Haemophilusinfluenzae) |
no annotation | 4 | LEU A 16TYR A 21LEU A 66TYR A 67 | None | 0.68A | 4z4fA-6dfuA:undetectable | 4z4fA-6dfuA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fdt | - (-) |
no annotation | 4 | TYR A 349LYS A 351LEU A 379GLU A 380 | None | 0.95A | 4z4fA-6fdtA:undetectable | 4z4fA-6fdtA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fgk | GTPPYROPHOSPHOKINASEYWAC (Bacillussubtilis) |
no annotation | 4 | LEU A 134TYR A 122LYS A 120GLU A 154 | None | 0.78A | 4z4fA-6fgkA:undetectable | 4z4fA-6fgkA:undetectable |