SIMILAR PATTERNS OF AMINO ACIDS FOR 4Y4D_A_CFFA411

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h4p GLUCAN
1,3-BETA-GLUCOSIDASE
I/II

(Saccharomyces
cerevisiae) 		PF00150
(Cellulase) 		4 LEU A  97
LEU A  64
ILE A  86
PHE A  73
 None
 1.27A 4y4dA-1h4pA:
0.0		 4y4dA-1h4pA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m93 SERINE PROTEINASE
INHIBITOR 2

(Cowpox virus) 		PF00079
(Serpin) 		4 ASP B 216
LEU B 214
ILE A  18
PHE A   4
 PO4  A 401 (-3.1A)
None
None
None
 1.20A 4y4dA-1m93B:
0.0		 4y4dA-1m93B:
24.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mpp PEPSIN

(Rhizomucor
pusillus) 		PF00026
(Asp) 		4 LEU A 306
LEU A 260
PHE A 305
ILE A 300
 None
 1.26A 4y4dA-1mppA:
37.8		 4y4dA-1mppA:
31.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nij HYPOTHETICAL PROTEIN
YJIA

(Escherichia
coli) 		PF02492
(cobW)
PF07683
(CobW_C) 		4 LEU A 117
LEU A 123
PHE A 111
PHE A 112
 None
 1.15A 4y4dA-1nijA:
0.0		 4y4dA-1nijA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nrf REGULATORY PROTEIN
BLAR1

(Bacillus
licheniformis) 		PF00905
(Transpeptidase) 		4 LEU A 590
PHE A 567
ILE A 388
PHE A 376
 None
 1.21A 4y4dA-1nrfA:
0.0		 4y4dA-1nrfA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o7x CITRATE SYNTHASE

(Sulfolobus
solfataricus) 		PF00285
(Citrate_synt) 		4 LEU A 298
LEU A 253
PHE A 242
ILE A 291
 None
 1.00A 4y4dA-1o7xA:
undetectable		 4y4dA-1o7xA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pby QUINOHEMOPROTEIN
AMINE DEHYDROGENASE
60 KDA SUBUNIT

(Paracoccus
denitrificans) 		PF09098
(Dehyd-heme_bind)
PF09099
(Qn_am_d_aIII)
PF09100
(Qn_am_d_aIV)
PF14930
(Qn_am_d_aII) 		4 LEU A 193
PHE A 251
ILE A 243
PHE A 244
 None
 1.26A 4y4dA-1pbyA:
0.0		 4y4dA-1pbyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vl4 PMBA-RELATED PROTEIN

(Thermotoga
maritima) 		PF01523
(PmbA_TldD) 		4 LEU A 235
LEU A 404
ILE A 240
PHE A 239
 None
 1.26A 4y4dA-1vl4A:
0.0		 4y4dA-1vl4A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wyo MICROTUBULE-ASSOCIAT
ED PROTEIN RP/EB
FAMILY MEMBER 3

(Homo sapiens) 		PF00307
(CH) 		4 LEU A  58
PHE A 122
ILE A 115
PHE A 118
 None
 1.13A 4y4dA-1wyoA:
undetectable		 4y4dA-1wyoA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ya0 SMG-7 TRANSCRIPT
VARIANT 2

(Homo sapiens) 		PF10373
(EST1_DNA_bind)
PF10374
(EST1) 		4 LEU A 272
LEU A 334
ILE A 254
PHE A 253
 None
 0.97A 4y4dA-1ya0A:
undetectable		 4y4dA-1ya0A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT

(Lactococcus
lactis) 		PF13393
(tRNA-synt_His) 		4 LEU A 144
LEU A 286
PHE A 274
ILE A 257
 None
 1.03A 4y4dA-1z7mA:
undetectable		 4y4dA-1z7mA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zbx ORIGIN RECOGNITION
COMPLEX SUBUNIT 1

(Saccharomyces
cerevisiae) 		PF01426
(BAH) 		4 LEU A 141
LEU A  50
ILE A 147
PHE A 146
 None
 1.27A 4y4dA-1zbxA:
undetectable		 4y4dA-1zbxA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cfo GLUTAMYL-TRNA
SYNTHETASE

(Synechococcus
elongatus) 		PF00749
(tRNA-synt_1c) 		4 LEU A 464
LEU A 359
PHE A 380
PHE A 381
 None
 1.09A 4y4dA-2cfoA:
undetectable		 4y4dA-2cfoA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cfz SDS HYDROLASE SDSA1

(Pseudomonas
aeruginosa) 		PF00753
(Lactamase_B)
PF14863
(Alkyl_sulf_dimr)
PF14864
(Alkyl_sulf_C) 		4 LEU A 320
ASP A 318
LEU A 308
ILE A 326
 None
 1.15A 4y4dA-2cfzA:
undetectable		 4y4dA-2cfzA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d5r CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 7

(Homo sapiens) 		PF04857
(CAF1) 		4 ASP A  70
LEU A  65
ILE A 184
PHE A 181
 None
 1.06A 4y4dA-2d5rA:
undetectable		 4y4dA-2d5rA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f1n CYTOLETHAL
DISTENDING TOXIN
SUBUNIT B

(Escherichia
coli) 		PF03372
(Exo_endo_phos) 		4 LEU A 167
LEU A   2
ILE A 125
PHE A 132
 None
 1.18A 4y4dA-2f1nA:
undetectable		 4y4dA-2f1nA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f5u VIRION PROTEIN UL25

(Human
alphaherpesvirus
1) 		PF01499
(Herpes_UL25) 		4 LEU A 546
LEU A 470
ILE A 573
PHE A 567
 None
 0.85A 4y4dA-2f5uA:
undetectable		 4y4dA-2f5uA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fel 3-CARBOXY-CIS,CIS-MU
CONATE LACTONIZING
ENZYME

(Agrobacterium
tumefaciens) 		PF00206
(Lyase_1) 		4 LEU A 336
LEU A 291
ILE A  21
PHE A   6
 None
 1.05A 4y4dA-2felA:
undetectable		 4y4dA-2felA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fna CONSERVED
HYPOTHETICAL PROTEIN

(Sulfolobus
solfataricus) 		PF01637
(ATPase_2) 		4 LEU A 281
LEU A 331
PHE A 280
ILE A 273
 None
 1.25A 4y4dA-2fnaA:
undetectable		 4y4dA-2fnaA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hpg ABC TRANSPORTER,
PERIPLASMIC
SUBSTRATE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF03480
(DctP) 		4 LEU A  92
LEU A 136
ILE A 243
PHE A 150
 None
 1.21A 4y4dA-2hpgA:
undetectable		 4y4dA-2hpgA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jak SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
56 KDA REGULATORY
SUBUNIT GAMMA
ISOFORM

(Homo sapiens) 		PF01603
(B56) 		4 LEU A 224
LEU A 254
PHE A 208
PHE A 211
 None
 1.06A 4y4dA-2jakA:
undetectable		 4y4dA-2jakA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2js9 SAPOSIN-LIKE PROTEIN
FAMILY PROTEIN 5

(Caenorhabditis
elegans) 		PF03489
(SapB_2) 		4 ASP A  32
LEU A  11
ILE A  42
PHE A  39
 None
 1.16A 4y4dA-2js9A:
undetectable		 4y4dA-2js9A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pv4 UNCHARACTERIZED
PROTEIN

(Shewanella
amazonensis) 		PF11269
(DUF3069) 		4 LEU A 125
PHE A  72
ILE A 144
PHE A  67
 None
 1.23A 4y4dA-2pv4A:
undetectable		 4y4dA-2pv4A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qkd ZINC FINGER PROTEIN
ZPR1

(Mus musculus) 		PF03367
(zf-ZPR1) 		4 LEU A 338
LEU A 358
ILE A 404
PHE A 403
 None
None
FMT  A 778 (-3.9A)
None
 1.25A 4y4dA-2qkdA:
undetectable		 4y4dA-2qkdA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9y ALPHA-2-ANTIPLASMIN

(Mus musculus) 		PF00079
(Serpin) 		4 LEU A 309
PHE A 263
ILE A 392
PHE A 271
 None
 1.13A 4y4dA-2r9yA:
undetectable		 4y4dA-2r9yA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vyc BIODEGRADATIVE
ARGININE
DECARBOXYLASE

(Escherichia
coli) 		PF01276
(OKR_DC_1)
PF03709
(OKR_DC_1_N)
PF03711
(OKR_DC_1_C) 		4 LEU A 594
PHE A 580
ILE A 534
PHE A 582
 None
 1.09A 4y4dA-2vycA:
undetectable		 4y4dA-2vycA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wbv FIBER PROTEIN

(Canine
mastadenovirus
A) 		no annotation 4 LEU A 482
LEU A 533
ILE A 383
PHE A 402
 None
 1.11A 4y4dA-2wbvA:
undetectable		 4y4dA-2wbvA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wc1 FLAVODOXIN

(Rhodobacter
capsulatus) 		PF00258
(Flavodoxin_1) 		4 LEU A 111
LEU A  97
ILE A  52
PHE A  95
 None
FMN  A 183 (-4.3A)
None
None
 1.25A 4y4dA-2wc1A:
undetectable		 4y4dA-2wc1A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwa LEUCINE CARBOXYL
METHYLTRANSFERASE 2

(Saccharomyces
cerevisiae) 		PF04072
(LCM)
PF13418
(Kelch_4) 		4 LEU A 164
PHE A  69
ILE A  35
PHE A  70
 None
 1.08A 4y4dA-2zwaA:
undetectable		 4y4dA-2zwaA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bq3 DEFECTIVE IN CULLIN
NEDDYLATION PROTEIN
1

(Saccharomyces
cerevisiae) 		PF03556
(Cullin_binding)
PF14555
(UBA_4) 		4 LEU A 131
LEU A 116
ILE A  83
PHE A  88
 None
 1.09A 4y4dA-3bq3A:
undetectable		 4y4dA-3bq3A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3buu UNCHARACTERIZED LOLA
SUPERFAMILY PROTEIN
NE2245

(Nitrosomonas
europaea) 		PF17131
(LolA_like) 		4 LEU A  41
ASP A  45
PHE A 139
ILE A 166
 None
 1.22A 4y4dA-3buuA:
undetectable		 4y4dA-3buuA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dhw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN

(Escherichia
coli) 		PF00005
(ABC_tran)
PF09383
(NIL) 		4 LEU C 247
ASP C 248
LEU C 340
ILE C 311
 None
 1.02A 4y4dA-3dhwC:
undetectable		 4y4dA-3dhwC:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dy5 ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN

(Plexaura
homomalla) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 LEU A 492
ASP A 892
LEU A 776
ILE A 878
 None
 1.13A 4y4dA-3dy5A:
undetectable		 4y4dA-3dy5A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epj TRNA
ISOPENTENYLTRANSFERA
SE

(Saccharomyces
cerevisiae) 		PF01715
(IPPT) 		4 LEU A 236
LEU A 264
PHE A 260
ILE A 258
 None
None
None
A  E  37 ( 3.9A)
 1.17A 4y4dA-3epjA:
undetectable		 4y4dA-3epjA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3exs RMPD
(HEXULOSE-6-PHOSPHAT
E SYNTHASE)

(Streptococcus
mutans) 		PF00215
(OMPdecase) 		4 LEU A 182
PHE A 193
ILE A 199
PHE A 212
 None
 1.16A 4y4dA-3exsA:
undetectable		 4y4dA-3exsA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fcr PUTATIVE
AMINOTRANSFERASE

(Ruegeria sp.
TM1040) 		PF00202
(Aminotran_3) 		4 LEU A 456
PHE A 397
ILE A 427
PHE A 387
 None
 1.05A 4y4dA-3fcrA:
undetectable		 4y4dA-3fcrA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fg4 ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN

(Plexaura
homomalla) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 LEU A 492
ASP A 892
LEU A 776
ILE A 878
 None
 1.13A 4y4dA-3fg4A:
undetectable		 4y4dA-3fg4A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fz5 POSSIBLE
2-HYDROXYCHROMENE-2-
CARBOXYLATE
ISOMERASE

(Rhodobacter
sphaeroides) 		PF01323
(DSBA) 		4 ASP A 114
LEU A  75
PHE A  16
ILE A  22
 CA  A 202 (-2.4A)
None
None
None
 1.11A 4y4dA-3fz5A:
undetectable		 4y4dA-3fz5A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g10 CCR4-NOT COMPLEX
SUBUNIT CAF1

(Schizosaccharomyces
pombe) 		PF04857
(CAF1) 		4 ASP A  80
LEU A  75
ILE A 194
PHE A 191
 None
 1.01A 4y4dA-3g10A:
undetectable		 4y4dA-3g10A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gb0 PEPTIDASE T

(Bacillus cereus) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 LEU A   7
LEU A  14
ILE A 119
PHE A 116
 None
 1.00A 4y4dA-3gb0A:
undetectable		 4y4dA-3gb0A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hc7 GENE 12 PROTEIN

(Mycobacterium
virus D29) 		PF01083
(Cutinase) 		4 LEU A 110
LEU A 151
PHE A 156
ILE A 114
 None
 1.27A 4y4dA-3hc7A:
undetectable		 4y4dA-3hc7A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ieg DNAJ HOMOLOG
SUBFAMILY C MEMBER 3

(Mus musculus) 		PF09976
(TPR_21)
PF13181
(TPR_8) 		4 ASP A 220
LEU A 251
ILE A 228
PHE A 225
 None
 1.24A 4y4dA-3iegA:
undetectable		 4y4dA-3iegA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kf3 INVERTASE

(Schwanniomyces
occidentalis) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 LEU A 477
LEU A 463
PHE A 438
ILE A 440
 None
 1.17A 4y4dA-3kf3A:
undetectable		 4y4dA-3kf3A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA

(Archaeoglobus
fulgidus) 		PF00037
(Fer4)
PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 LEU B 103
PHE B  92
ILE B  51
PHE B  93
 None
 1.21A 4y4dA-3mm5B:
undetectable		 4y4dA-3mm5B:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nh9 ATP-BINDING CASSETTE
SUB-FAMILY B MEMBER
6, MITOCHONDRIAL

(Homo sapiens) 		PF00005
(ABC_tran) 		4 LEU A 795
LEU A 606
ILE A 590
PHE A 592
 None
 1.16A 4y4dA-3nh9A:
undetectable		 4y4dA-3nh9A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nrg TETR FAMILY
TRANSCRIPTIONAL
REGULATOR

(Chloroflexus
aurantiacus) 		PF00440
(TetR_N) 		4 LEU A 140
LEU A 150
ILE A 206
PHE A  87
 None
 1.20A 4y4dA-3nrgA:
undetectable		 4y4dA-3nrgA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		4 LEU A 214
LEU A 233
ILE A 237
PHE A 235
 None
 1.14A 4y4dA-3p9uA:
undetectable		 4y4dA-3p9uA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pie 5'->3'
EXORIBONUCLEASE
(XRN1)

(Kluyveromyces
lactis) 		PF03159
(XRN_N) 		4 LEU A 317
LEU A 310
ILE A 282
PHE A 281
 None
 1.11A 4y4dA-3pieA:
undetectable		 4y4dA-3pieA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rko NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT K
NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT N

(Escherichia
coli) 		no annotation 4 LEU N 170
LEU K  68
PHE N 129
ILE N 135
 None
 1.04A 4y4dA-3rkoN:
undetectable		 4y4dA-3rkoN:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sdq ALPHA-BISABOLENE
SYNTHASE

(Abies grandis) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 LEU A 690
ASP A 694
LEU A 779
ILE A 679
 None
 1.19A 4y4dA-3sdqA:
undetectable		 4y4dA-3sdqA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sun DNA POLYMERASE

(Escherichia
virus RB69) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		4 LEU A 725
LEU A 730
ILE A 698
PHE A 701
 None
 1.25A 4y4dA-3sunA:
undetectable		 4y4dA-3sunA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u24 PUTATIVE LIPOPROTEIN

(Shewanella
oneidensis) 		PF05960
(DUF885) 		4 LEU A  62
LEU A  73
ILE A 148
PHE A 144
 None
EDO  A 600 (-4.8A)
None
None
 1.06A 4y4dA-3u24A:
undetectable		 4y4dA-3u24A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uws HYPOTHETICAL PROTEIN

(Parabacteroides
merdae) 		PF03415
(Peptidase_C11) 		4 LEU B 248
LEU B 223
ILE B 174
PHE B 173
 None
EDO  B 401 (-4.8A)
None
None
 1.12A 4y4dA-3uwsB:
undetectable		 4y4dA-3uwsB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vf1 11R-LIPOXYGENASE

(Gersemia
fruticosa) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 LEU A 121
ASP A 505
LEU A 392
ILE A 491
 None
 1.08A 4y4dA-3vf1A:
undetectable		 4y4dA-3vf1A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vth HYDROGENASE
MATURATION FACTOR

(Caldanaerobacter
subterraneus) 		PF00708
(Acylphosphatase)
PF01300
(Sua5_yciO_yrdC)
PF07503
(zf-HYPF) 		4 LEU A 607
LEU A 624
ILE A 652
PHE A 673
 None
 1.05A 4y4dA-3vthA:
undetectable		 4y4dA-3vthA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ab5 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Neisseria
meningitidis) 		PF03466
(LysR_substrate) 		4 LEU A 205
ASP A 202
LEU A 212
ILE A 196
 None
 1.04A 4y4dA-4ab5A:
undetectable		 4y4dA-4ab5A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4azv WBDD

(Escherichia
coli) 		PF00069
(Pkinase)
PF13847
(Methyltransf_31) 		4 LEU A  37
LEU A 128
PHE A  67
ILE A  78
 None
SAM  A1474 (-4.3A)
SAM  A1474 (-4.8A)
None
 0.88A 4y4dA-4azvA:
undetectable		 4y4dA-4azvA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b0z 26S PROTEASOME
REGULATORY SUBUNIT
RPN12

(Schizosaccharomyces
pombe) 		PF10075
(CSN8_PSD8_EIF3K) 		4 LEU A  97
PHE A 160
ILE A 166
PHE A 163
 None
 1.08A 4y4dA-4b0zA:
undetectable		 4y4dA-4b0zA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d5r A49

(Vaccinia virus) 		PF06489
(Orthopox_A49R) 		4 LEU A 151
LEU A 106
ILE A  27
PHE A  64
 None
 1.21A 4y4dA-4d5rA:
undetectable		 4y4dA-4d5rA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dks PROBABLE INTEGRASE

(Sulfolobus
spindle-shaped
virus 1) 		PF16795
(Phage_integr_3) 		4 LEU A 206
PHE A 280
ILE A 178
PHE A 283
 None
 1.26A 4y4dA-4dksA:
undetectable		 4y4dA-4dksA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gmj CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 7

(Homo sapiens) 		PF04857
(CAF1) 		4 ASP B  70
LEU B  65
ILE B 184
PHE B 181
 None
 0.95A 4y4dA-4gmjB:
undetectable		 4y4dA-4gmjB:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h1l ANI2.3 TCR A CHAIN

(Escherichia
coli) 		PF07686
(V-set) 		4 LEU G  43
PHE G  89
ILE G 102
PHE G 103
 None
 1.13A 4y4dA-4h1lG:
undetectable		 4y4dA-4h1lG:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 13

(Thermus
thermophilus) 		PF00361
(Proton_antipo_M) 		4 LEU M  70
PHE M 239
ILE M 246
PHE M 242
 None
 1.26A 4y4dA-4heaM:
undetectable		 4y4dA-4heaM:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hyr GLUCARATE
DEHYDRATASE

(Acidaminococcus
intestini) 		PF13378
(MR_MLE_C) 		4 LEU A 187
LEU A 202
ILE A 179
PHE A 149
 None
 0.76A 4y4dA-4hyrA:
undetectable		 4y4dA-4hyrA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j75 TRYPTOPHANYL-TRNA
SYNTHETASE

(Plasmodium
falciparum) 		PF00579
(tRNA-synt_1b) 		4 ASP A 345
LEU A 392
ILE A 382
PHE A 383
 None
 1.10A 4y4dA-4j75A:
undetectable		 4y4dA-4j75A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jc8 HOPS COMPONENT VPS33

(Chaetomium
thermophilum) 		PF00995
(Sec1) 		4 LEU A  39
LEU A  20
ILE A 109
PHE A 110
 None
 1.22A 4y4dA-4jc8A:
undetectable		 4y4dA-4jc8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k2u ERYTHROCYTE BINDING
ANTIGEN 175

(Plasmodium
falciparum) 		PF03011
(PFEMP)
PF05424
(Duffy_binding) 		4 LEU A 188
LEU A 270
PHE A 187
ILE A 180
 None
 1.27A 4y4dA-4k2uA:
undetectable		 4y4dA-4k2uA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kam O-ACETYLHOMOSERINE
SULFHYDRYLASE METC

(Mycobacterium
marinum) 		PF01053
(Cys_Met_Meta_PP) 		4 LEU A 277
LEU A  94
PHE A 103
ILE A 213
 None
 1.12A 4y4dA-4kamA:
undetectable		 4y4dA-4kamA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mu9 GLYCOSIDE HYDROLASE
FAMILY 73

(Bacteroides
thetaiotaomicron) 		PF03663
(Glyco_hydro_76) 		4 LEU A 344
PHE A  27
ILE A  34
PHE A 382
 None
 1.22A 4y4dA-4mu9A:
undetectable		 4y4dA-4mu9A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rt6 HEME/HEMOPEXIN-BINDI
NG PROTEIN

(Haemophilus
influenzae) 		PF05860
(Haemagg_act) 		4 LEU A 627
LEU A 589
ILE A 510
PHE A 508
 None
 1.12A 4y4dA-4rt6A:
undetectable		 4y4dA-4rt6A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tqv ALGM2

(Sphingomonas
sp.) 		PF00528
(BPD_transp_1) 		4 ASP B 136
LEU B 140
ILE B 128
PHE B 131
 None
 0.74A 4y4dA-4tqvB:
undetectable		 4y4dA-4tqvB:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uvk ZYRO0D15994P

(Zygosaccharomyces
rouxii) 		PF08514
(STAG) 		4 LEU A 662
LEU A 702
ILE A 694
PHE A 697
 None
 1.07A 4y4dA-4uvkA:
undetectable		 4y4dA-4uvkA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wfw GENERAL SECRETION
PATHWAY PROTEIN B

(Dickeya
dadantii) 		PF16537
(T2SSB) 		4 LEU A 127
PHE A 177
ILE A 183
PHE A 182
 None
 1.09A 4y4dA-4wfwA:
undetectable		 4y4dA-4wfwA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xng UNCHARACTERIZED
PROTEIN MG218.1

(Mycoplasma
genitalium) 		no annotation 4 LEU A  84
LEU A 154
PHE A  81
ILE A 141
 None
 0.97A 4y4dA-4xngA:
undetectable		 4y4dA-4xngA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bp7 SAM-DEPENDENT
METHYLTRANSFERASE

(Geobacter
sulfurreducens) 		PF13847
(Methyltransf_31) 		4 LEU A  29
LEU A 187
ILE A 139
PHE A 244
 None
 1.24A 4y4dA-5bp7A:
undetectable		 4y4dA-5bp7A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e26 PANTOTHENATE KINASE
2, MITOCHONDRIAL

(Homo sapiens) 		PF03630
(Fumble) 		4 LEU A 524
LEU A 435
ILE A 497
PHE A 418
 None
 1.04A 4y4dA-5e26A:
undetectable		 4y4dA-5e26A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f5o NUCLEOPROTEIN

(Marburg
marburgvirus) 		PF05505
(Ebola_NP) 		4 LEU A 119
LEU A 112
ILE A  34
PHE A  99
 None
 1.27A 4y4dA-5f5oA:
undetectable		 4y4dA-5f5oA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsw RNA DEPENDENT RNA
POLYMERASE QDE-1

(Thielavia
terrestris) 		PF05183
(RdRP) 		4 LEU A 277
LEU A 153
ILE A 691
PHE A 206
 None
 1.16A 4y4dA-5fswA:
undetectable		 4y4dA-5fswA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fub PROTEIN ARGININE
METHYLTRANSFERASE 2

(Danio rerio) 		PF13649
(Methyltransf_25) 		4 LEU A 352
LEU A 355
ILE A 227
PHE A 317
 None
 1.26A 4y4dA-5fubA:
undetectable		 4y4dA-5fubA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5guh PIWI

(Bombyx mori) 		PF02170
(PAZ)
PF02171
(Piwi) 		4 LEU A 304
LEU A 479
ILE A 248
PHE A 251
 None
 1.07A 4y4dA-5guhA:
undetectable		 4y4dA-5guhA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzs GGDEF FAMILY PROTEIN

(Vibrio cholerae) 		PF00497
(SBP_bac_3) 		4 LEU A 256
LEU A 307
ILE A 479
PHE A 475
 None
 1.21A 4y4dA-5gzsA:
undetectable		 4y4dA-5gzsA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h64 SERINE/THREONINE-PRO
TEIN KINASE MTOR

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08771
(FRB_dom)
PF11865
(DUF3385) 		4 LEU A1142
ASP A1147
LEU A1115
ILE A1156
 None
 1.20A 4y4dA-5h64A:
undetectable		 4y4dA-5h64A:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hcc COMPLEMENT C5

(Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF07677
(A2M_recep)
PF07678
(A2M_comp) 		4 ASP A1330
LEU A 982
PHE A1333
ILE A1313
 None
 1.17A 4y4dA-5hccA:
undetectable		 4y4dA-5hccA:
16.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5hct ENDOTHIAPEPSIN

(Cryphonectria
parasitica) 		PF00026
(Asp) 		6 LEU A  13
ASP A  15
LEU A 224
PHE A 280
ILE A 283
PHE A 291
 PG4  A 408 ( 4.9A)
PG4  A 408 (-3.7A)
PG4  A 408 ( 4.3A)
PG4  A 408 (-4.5A)
PG4  A 408 (-4.8A)
PG4  A 408 ( 4.0A)
 0.05A 4y4dA-5hctA:
58.6		 4y4dA-5hctA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE

(Porphyromonas
endodontalis) 		PF10459
(Peptidase_S46) 		4 LEU A 232
LEU A 120
ILE A 229
PHE A 230
 None
 1.24A 4y4dA-5jxkA:
undetectable		 4y4dA-5jxkA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kuf GLUTAMATE RECEPTOR
IONOTROPIC, KAINATE
2

(Rattus
norvegicus) 		PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd) 		4 LEU A 230
LEU A 208
ILE A 196
PHE A 197
 None
 1.14A 4y4dA-5kufA:
undetectable		 4y4dA-5kufA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5log PUTATIVE
O-METHYLTRANSFERASE

(Myxococcus
xanthus) 		PF01596
(Methyltransf_3) 		4 LEU A 164
LEU A  51
ILE A 141
PHE A 140
 None
 1.26A 4y4dA-5logA:
undetectable		 4y4dA-5logA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lw0 BASIC
HELIX-LOOP-HELIX,
PUTATIVE, EXPRESSED

(Oryza sativa) 		PF01661
(Macro) 		4 LEU A 140
PHE A 288
ILE A 294
PHE A 291
 None
 1.03A 4y4dA-5lw0A:
undetectable		 4y4dA-5lw0A:
19.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5p60 ENDOTHIAPEPSIN

(Cryphonectria
parasitica) 		PF00026
(Asp) 		6 LEU A  13
ASP A  15
LEU A 224
PHE A 280
ILE A 283
PHE A 291
 None
 0.09A 4y4dA-5p60A:
58.7		 4y4dA-5p60A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tfm CADHERIN-23

(Homo sapiens) 		no annotation 4 LEU A 817
LEU A 829
PHE A 800
ILE A 810
 None
 1.19A 4y4dA-5tfmA:
undetectable		 4y4dA-5tfmA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uco 2,4,6-TRIHYDROXYBENZ
OPHENONE SYNTHASE

(Hypericum
androsaemum) 		no annotation 4 LEU A 353
LEU A 388
PHE A 303
ILE A 306
 None
 1.19A 4y4dA-5ucoA:
undetectable		 4y4dA-5ucoA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ver KYNURENINE--OXOGLUTA
RATE TRANSAMINASE 3

(Mus musculus) 		no annotation 4 LEU A 440
LEU A 408
ILE A 374
PHE A 431
 None
 0.90A 4y4dA-5verA:
undetectable		 4y4dA-5verA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8q BIS3 BIPHENYL
SYNTHASE

(Malus domestica) 		no annotation 4 LEU A 381
PHE A 296
ILE A 368
PHE A 297
 None
 1.25A 4y4dA-5w8qA:
undetectable		 4y4dA-5w8qA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xgw ISOASPARTYL
DIPEPTIDASE

(Colwellia
psychrerythraea) 		no annotation 4 ASP A 111
LEU A 144
ILE A 169
PHE A 167
 None
 1.13A 4y4dA-5xgwA:
undetectable		 4y4dA-5xgwA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r X-RAY REPAIR
CROSS-COMPLEMENTING
PROTEIN 6

(Homo sapiens) 		PF02735
(Ku)
PF03730
(Ku_C)
PF03731
(Ku_N) 		4 LEU A  38
ASP A  81
LEU A 108
ILE A  67
 None
 1.13A 4y4dA-5y3rA:
undetectable		 4y4dA-5y3rA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bfn INTERLEUKIN-1
RECEPTOR-ASSOCIATED
KINASE 1

(Homo sapiens) 		no annotation 4 LEU A 501
LEU A 496
ILE A 341
PHE A 410
 None
 1.25A 4y4dA-6bfnA:
undetectable		 4y4dA-6bfnA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d9h CHIMERA PROTEIN OF
MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4 AND
ADENOSINE RECEPTOR
A1

(Homo sapiens) 		no annotation 4 LEU R  29
PHE R 299
ILE R 292
PHE R 295
 None
 0.93A 4y4dA-6d9hR:
undetectable		 4y4dA-6d9hR:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5d ATP SYNTHASE DELTA
SUBUNIT
ATP SYNTHASE GAMMA
SUBUNIT

(Trypanosoma
brucei) 		no annotation 4 LEU H  75
LEU G 212
PHE H  98
ILE H 101
 None
 1.08A 4y4dA-6f5dH:
undetectable		 4y4dA-6f5dH:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fml INO80

(Chaetomium
thermophilum) 		no annotation 4 LEU G1599
LEU G1637
ILE G1621
PHE G1615
 None
 1.25A 4y4dA-6fmlG:
undetectable		 4y4dA-6fmlG:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fra HUMAN T-CELL
RECEPTOR F11 ALPHA
CHAIN

(Homo sapiens) 		no annotation 4 LEU A  44
PHE A  90
ILE A 101
PHE A 102
 EDO  A 304 (-4.9A)
None
None
EDO  A 306 ( 4.1A)
 1.26A 4y4dA-6fraA:
undetectable		 4y4dA-6fraA:
14.85