SIMILAR PATTERNS OF AMINO ACIDS FOR 4Y0R_A_PX9A201_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bvw PROTEIN
(CELLOBIOHYDROLASE
II)


(Humicola
insolens)
PF01341
(Glyco_hydro_6)
5 LEU A 148
LEU A 138
ILE A 207
ILE A 204
MET A 265
None
0.88A 4y0rA-1bvwA:
0.0
4y0rA-1bvwA:
17.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1exs BETA-LACTOGLOBULIN

(Sus scrofa)
PF00061
(Lipocalin)
5 LEU A  46
LEU A  54
ILE A  56
LEU A  58
ILE A  84
None
0.62A 4y0rA-1exsA:
14.9
4y0rA-1exsA:
64.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezv UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I


(Saccharomyces
cerevisiae)
PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
5 LEU A 342
ILE A 343
LEU A 347
ILE A 447
ILE A 432
None
0.91A 4y0rA-1ezvA:
1.4
4y0rA-1ezvA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gtk PORPHOBILINOGEN
DEAMINASE


(Escherichia
coli)
PF01379
(Porphobil_deam)
PF03900
(Porphobil_deamC)
5 LEU A  38
ILE A   8
LEU A   6
ILE A  77
ILE A 203
None
0.85A 4y0rA-1gtkA:
undetectable
4y0rA-1gtkA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j1v CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA


(Escherichia
coli)
PF08299
(Bac_DnaA_C)
5 LEU A 465
LEU A 417
ILE A 379
ILE A 376
ILE A 425
None
1.03A 4y0rA-1j1vA:
undetectable
4y0rA-1j1vA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jfl ASPARTATE RACEMASE

(Pyrococcus
horikoshii)
PF01177
(Asp_Glu_race)
5 LEU A 206
LEU A 210
ILE A 190
LEU A 182
VAL A 197
None
0.95A 4y0rA-1jflA:
undetectable
4y0rA-1jflA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ktw IOTA-CARRAGEENASE

(Alteromonas sp.
ATCC 43554)
PF12708
(Pectate_lyase_3)
5 VAL A 161
LEU A  69
LEU A 126
VAL A 107
PHE A 140
None
1.05A 4y0rA-1ktwA:
0.0
4y0rA-1ktwA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE


(Escherichia
coli)
PF01380
(SIS)
5 LEU A 371
LEU A 342
ILE A 344
LEU A 346
ILE A 297
None
0.83A 4y0rA-1morA:
0.1
4y0rA-1morA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vi1 FATTY
ACID/PHOSPHOLIPID
SYNTHESIS PROTEIN
PLSX


(Bacillus
subtilis)
PF02504
(FA_synthesis)
5 LEU A  35
ILE A  33
LEU A  31
ILE A   3
ILE A  96
None
0.92A 4y0rA-1vi1A:
undetectable
4y0rA-1vi1A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vtl TATA BINDING PROTEIN
(TBP)


(Arabidopsis
thaliana)
PF00352
(TBP)
5 ILE E 128
LEU E 133
ILE E 164
ILE E 170
VAL E 124
None
0.81A 4y0rA-1vtlE:
3.5
4y0rA-1vtlE:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xg2 PECTINESTERASE 1

(Solanum
lycopersicum)
PF01095
(Pectinesterase)
5 LEU A  94
ILE A  57
LEU A  55
ILE A  35
VAL A  46
None
1.07A 4y0rA-1xg2A:
undetectable
4y0rA-1xg2A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xg2 PECTINESTERASE 1

(Solanum
lycopersicum)
PF01095
(Pectinesterase)
5 VAL A  46
LEU A  85
ILE A  57
ILE A  35
VAL A   7
None
1.02A 4y0rA-1xg2A:
undetectable
4y0rA-1xg2A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xm7 HYPOTHETICAL PROTEIN
AQ_1665


(Aquifex
aeolicus)
PF12850
(Metallophos_2)
5 LEU A 109
ILE A 142
LEU A 140
ILE A 165
ILE A 177
None
0.75A 4y0rA-1xm7A:
undetectable
4y0rA-1xm7A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xm7 HYPOTHETICAL PROTEIN
AQ_1665


(Aquifex
aeolicus)
PF12850
(Metallophos_2)
5 LEU A 109
LEU A  48
ILE A 142
LEU A 140
ILE A 177
None
0.96A 4y0rA-1xm7A:
undetectable
4y0rA-1xm7A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xm7 HYPOTHETICAL PROTEIN
AQ_1665


(Aquifex
aeolicus)
PF12850
(Metallophos_2)
5 LEU A 140
ILE A 107
LEU A 109
LYS A  98
ILE A 100
None
0.90A 4y0rA-1xm7A:
undetectable
4y0rA-1xm7A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yq2 BETA-GALACTOSIDASE

(Arthrobacter
sp. C2-2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981)
5 LEU A 935
LEU A 933
LEU A 752
ILE A1020
VAL A 987
None
0.87A 4y0rA-1yq2A:
undetectable
4y0rA-1yq2A:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dgx KIAA0430 PROTEIN

(Homo sapiens)
PF00076
(RRM_1)
5 VAL A 602
LEU A 598
ILE A 562
ILE A 627
ILE A 622
None
0.79A 4y0rA-2dgxA:
undetectable
4y0rA-2dgxA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e87 HYPOTHETICAL PROTEIN
PH1320


(Pyrococcus
horikoshii)
PF06858
(NOG1)
5 LEU A 284
LEU A 249
ILE A 251
ILE A 172
ILE A 218
None
0.80A 4y0rA-2e87A:
undetectable
4y0rA-2e87A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hzs RNA POLYMERASE II
MEDIATOR COMPLEX
SUBUNIT 20


(Saccharomyces
cerevisiae)
PF08612
(Med20)
5 LEU A 139
LEU A 151
ILE A 153
GLU A 164
ILE A   7
None
0.95A 4y0rA-2hzsA:
1.8
4y0rA-2hzsA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j6h GLUCOSAMINE-FRUCTOSE
-6-PHOSPHATE
AMINOTRANSFERASE


(Escherichia
coli)
PF01380
(SIS)
PF13522
(GATase_6)
5 LEU A 371
LEU A 342
ILE A 344
LEU A 346
ILE A 297
None
0.82A 4y0rA-2j6hA:
undetectable
4y0rA-2j6hA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jaq DEOXYGUANOSINE
KINASE


(Mycoplasma
mycoides)
PF01712
(dNK)
5 VAL A 181
ILE A   5
LEU A 131
ILE A  16
ILE A  20
None
0.93A 4y0rA-2jaqA:
undetectable
4y0rA-2jaqA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jcs DEOXYNUCLEOSIDE
KINASE


(Drosophila
melanogaster)
PF01712
(dNK)
5 LEU A 203
LEU A 149
ILE A 151
ILE A  25
ILE A 102
None
0.66A 4y0rA-2jcsA:
undetectable
4y0rA-2jcsA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jcs DEOXYNUCLEOSIDE
KINASE


(Drosophila
melanogaster)
PF01712
(dNK)
5 LEU A 203
LEU A 149
ILE A 151
LEU A 153
ILE A  25
None
0.89A 4y0rA-2jcsA:
undetectable
4y0rA-2jcsA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ocp DEOXYGUANOSINE
KINASE


(Homo sapiens)
PF01712
(dNK)
5 LEU A 248
ILE A 190
LEU A 192
ILE A  43
ILE A 139
None
1.01A 4y0rA-2ocpA:
undetectable
4y0rA-2ocpA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ok8 PUTATIVE
FERREDOXIN--NADP
REDUCTASE


(Plasmodium
falciparum)
PF00175
(NAD_binding_1)
5 LEU A 114
ILE A  40
LEU A  38
LYS A  23
ILE A  20
None
1.01A 4y0rA-2ok8A:
undetectable
4y0rA-2ok8A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ow4 CANAVALIA MARITIMA
LECTIN


(Canavalia rosea)
PF00139
(Lectin_legB)
5 VAL A  65
LEU A  93
LEU A 156
ILE A 210
ILE A 199
None
0.95A 4y0rA-2ow4A:
undetectable
4y0rA-2ow4A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyy IONOTROPIC GLUTAMATE
RECEPTOR BACTERIAL
HOMOLOGUE


(Nostoc
punctiforme)
PF00497
(SBP_bac_3)
5 VAL A   7
ILE A 186
LEU A  64
ILE A 198
ILE A  34
None
0.90A 4y0rA-2pyyA:
undetectable
4y0rA-2pyyA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qby CELL DIVISION
CONTROL PROTEIN 6
HOMOLOG 1


(Sulfolobus
solfataricus)
PF09079
(Cdc6_C)
PF13401
(AAA_22)
5 VAL A 144
ILE A  61
ILE A  59
ILE A  43
VAL A  72
None
1.00A 4y0rA-2qbyA:
undetectable
4y0rA-2qbyA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v1u CELL DIVISION
CONTROL PROTEIN 6
HOMOLOG


(Aeropyrum
pernix)
PF09079
(Cdc6_C)
PF13191
(AAA_16)
5 LEU A 182
LEU A 148
ILE A 146
LYS A  92
ILE A  94
None
0.81A 4y0rA-2v1uA:
undetectable
4y0rA-2v1uA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vvf MAJOR CAPSID PROTEIN
P2


(Pseudoalteromonas
virus PM2)
no annotation 5 LEU A  23
LEU A   7
ILE A  21
ILE A  10
PHE A  83
None
0.96A 4y0rA-2vvfA:
undetectable
4y0rA-2vvfA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywm GLUTAREDOXIN-LIKE
PROTEIN


(Aquifex
aeolicus)
PF13192
(Thioredoxin_3)
5 LEU A  14
ILE A 110
LEU A 109
ILE A 113
ILE A  51
None
0.86A 4y0rA-2ywmA:
undetectable
4y0rA-2ywmA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zay RESPONSE REGULATOR
RECEIVER PROTEIN


(Desulfuromonas
acetoxidans)
PF00072
(Response_reg)
5 LEU A  13
ILE A  57
ILE A  86
ILE A 109
VAL A 113
None
0.84A 4y0rA-2zayA:
undetectable
4y0rA-2zayA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zay RESPONSE REGULATOR
RECEIVER PROTEIN


(Desulfuromonas
acetoxidans)
PF00072
(Response_reg)
5 LEU A  13
ILE A  57
LEU A  55
ILE A  86
ILE A 109
None
1.06A 4y0rA-2zayA:
undetectable
4y0rA-2zayA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1z HEMOLYMPH JUVENILE
HORMONE BINDING
PROTEIN


(Bombyx mori)
PF06585
(JHBP)
5 VAL A 122
LEU A  48
ILE A 196
ILE A  97
ILE A  67
None
1.06A 4y0rA-3a1zA:
undetectable
4y0rA-3a1zA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3brq HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ASCG


(Escherichia
coli)
PF13377
(Peripla_BP_3)
5 ILE A  91
LEU A  86
GLU A  62
ILE A  94
ILE A 102
None
0.86A 4y0rA-3brqA:
undetectable
4y0rA-3brqA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3crw XPD/RAD3 RELATED DNA
HELICASE


(Sulfolobus
acidocaldarius)
PF06733
(DEAD_2)
PF13307
(Helicase_C_2)
5 LEU 1  24
LEU 1 320
ILE 1 318
LEU 1 316
ILE 1 177
None
1.00A 4y0rA-3crw1:
undetectable
4y0rA-3crw1:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dtc MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 9


(Homo sapiens)
PF07714
(Pkinase_Tyr)
5 ILE A 249
LEU A 338
ILE A 274
ILE A 292
PHE A 396
None
1.04A 4y0rA-3dtcA:
undetectable
4y0rA-3dtcA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fxq LYSR TYPE REGULATOR
OF TSAMBCD


(Comamonas
testosteroni)
PF00126
(HTH_1)
PF03466
(LysR_substrate)
5 LEU A 265
ILE A 170
LEU A 239
ILE A 259
PHE A 209
None
0.88A 4y0rA-3fxqA:
undetectable
4y0rA-3fxqA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1l CYTOCHROME B

(Gallus gallus)
PF00032
(Cytochrom_B_C)
PF00033
(Cytochrome_B)
5 VAL C 299
LEU C 302
ILE C  99
ILE C  95
MET C 125
None
HEM  C 502 ( 4.9A)
HEM  C 502 (-3.9A)
None
3H1  C2001 ( 4.7A)
0.82A 4y0rA-3h1lC:
undetectable
4y0rA-3h1lC:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hcw MALTOSE OPERON
TRANSCRIPTIONAL
REPRESSOR


(Staphylococcus
aureus)
PF13377
(Peripla_BP_3)
5 LEU A  64
LEU A 127
ILE A 125
ILE A 147
ILE A 163
None
0.68A 4y0rA-3hcwA:
undetectable
4y0rA-3hcwA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i0m DNA REPAIR AND
TELOMERE MAINTENANCE
PROTEIN NBS1


(Schizosaccharomyces
pombe)
PF00498
(FHA)
5 LEU A  98
ILE A 100
LEU A 102
ILE A 109
ILE A   4
None
0.98A 4y0rA-3i0mA:
undetectable
4y0rA-3i0mA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4t DIPHTHINE SYNTHASE

(Entamoeba
histolytica)
PF00590
(TP_methylase)
5 LEU A  80
LEU A   7
ILE A   5
LYS A 106
ILE A 108
None
0.65A 4y0rA-3i4tA:
undetectable
4y0rA-3i4tA:
21.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kza BETA-LACTOGLOBULIN

(Equus caballus;
Bos taurus)
PF00061
(Lipocalin)
7 VAL A  41
LEU A  46
LEU A  54
ILE A  56
ILE A  84
VAL A  92
PHE A 105
None
0.59A 4y0rA-3kzaA:
24.9
4y0rA-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kza BETA-LACTOGLOBULIN

(Equus caballus;
Bos taurus)
PF00061
(Lipocalin)
7 VAL A  41
LEU A  46
LEU A  54
ILE A  56
LEU A  58
ILE A  71
ILE A  84
None
0.72A 4y0rA-3kzaA:
24.9
4y0rA-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kza BETA-LACTOGLOBULIN

(Equus caballus;
Bos taurus)
PF00061
(Lipocalin)
6 VAL A  41
LEU A  46
LEU A  54
VAL A  92
PHE A 105
MET A 107
None
0.48A 4y0rA-3kzaA:
24.9
4y0rA-3kzaA:
81.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6u LYSR TYPE REGULATOR
OF TSAMBCD


(Comamonas
testosteroni)
PF03466
(LysR_substrate)
5 LEU A 265
ILE A 170
LEU A 239
ILE A 259
PHE A 209
None
0.87A 4y0rA-3n6uA:
undetectable
4y0rA-3n6uA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o5y SENSOR PROTEIN

(Bacillus
halodurans)
PF13492
(GAF_3)
5 LEU A 102
ILE A 118
LEU A 116
ILE A  30
VAL A  25
None
0.81A 4y0rA-3o5yA:
undetectable
4y0rA-3o5yA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odp PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE


(Clostridium
novyi)
PF01380
(SIS)
5 LEU A 163
LEU A 140
ILE A 142
GLU A 246
ILE A  62
None
0.81A 4y0rA-3odpA:
undetectable
4y0rA-3odpA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ouk PROBABLE CONSERVED
TRANSMEMBRANE
PROTEIN


(Mycobacterium
tuberculosis)
no annotation 5 VAL A 164
LEU A 252
ILE A 184
LEU A 134
ILE A 150
None
0.94A 4y0rA-3oukA:
undetectable
4y0rA-3oukA:
21.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ph5 BETA-LACTOGLOBULIN

(Bos taurus)
PF00061
(Lipocalin)
7 VAL A  57
LEU A  62
GLU A  78
LYS A  85
VAL A 108
PHE A 121
MET A 123
None
0.84A 4y0rA-3ph5A:
28.7
4y0rA-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ph5 BETA-LACTOGLOBULIN

(Bos taurus)
PF00061
(Lipocalin)
7 VAL A  57
LEU A  62
LEU A  70
GLU A  78
LYS A  85
VAL A 108
PHE A 121
None
0.72A 4y0rA-3ph5A:
28.7
4y0rA-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ph5 BETA-LACTOGLOBULIN

(Bos taurus)
PF00061
(Lipocalin)
8 VAL A  57
LEU A  62
LEU A  70
ILE A  72
LEU A  74
GLU A  78
ILE A  87
ILE A 100
None
0.64A 4y0rA-3ph5A:
28.7
4y0rA-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ph5 BETA-LACTOGLOBULIN

(Bos taurus)
PF00061
(Lipocalin)
9 VAL A  57
LEU A  62
LEU A  70
ILE A  72
LEU A  74
GLU A  78
ILE A 100
VAL A 108
PHE A 121
None
0.66A 4y0rA-3ph5A:
28.7
4y0rA-3ph5A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q6z POLY [ADP-RIBOSE]
POLYMERASE 14


(Homo sapiens)
PF01661
(Macro)
5 LEU A 804
LEU A 959
ILE A 957
LEU A 954
ILE A 916
None
1.06A 4y0rA-3q6zA:
undetectable
4y0rA-3q6zA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3trr PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE


(Mycobacteroides
abscessus)
PF00378
(ECH_1)
5 LEU A  14
ILE A  16
LEU A  35
ILE A  53
ILE A  92
None
1.03A 4y0rA-3trrA:
undetectable
4y0rA-3trrA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3up6 HYPOTHETICAL PROTEIN
BACOVA_04078


(Bacteroides
ovatus)
no annotation 5 LEU A  43
ILE A  41
LEU A  39
LYS A 167
ILE A 156
None
0.93A 4y0rA-3up6A:
undetectable
4y0rA-3up6A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vom PUTATIVE
PHOSPHOSERINE
AMINOTRANSFERASE


(Mycobacterium
tuberculosis)
PF00266
(Aminotran_5)
5 VAL A 162
LEU A 274
LEU A  68
ILE A 188
ILE A 212
None
0.89A 4y0rA-3vomA:
undetectable
4y0rA-3vomA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvs PUTATIVE
MONOOXYGENASE


(Streptomyces
sp. SN-593)
PF00067
(p450)
5 LEU A 232
ILE A 197
GLU A 163
ILE A 200
ILE A 213
None
1.02A 4y0rA-3wvsA:
undetectable
4y0rA-3wvsA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdf GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Thermosynechococcus
elongatus)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
5 LEU A 121
LEU A  95
ILE A  97
ILE A   6
ILE A  31
None
0.58A 4y0rA-3zdfA:
undetectable
4y0rA-3zdfA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zhn PA_0080

(Pseudomonas
aeruginosa)
PF12790
(T6SS-SciN)
5 LEU A  16
LEU A 125
ILE A 123
LEU A 121
ILE A 132
None
0.81A 4y0rA-3zhnA:
undetectable
4y0rA-3zhnA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zq4 RIBONUCLEASE J 1

(Bacillus
subtilis)
PF00753
(Lactamase_B)
PF07521
(RMMBL)
5 VAL A 515
LEU A 507
ILE A 508
LEU A 512
ILE A 530
None
1.05A 4y0rA-3zq4A:
1.4
4y0rA-3zq4A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zus BOTULINUM NEUROTOXIN
TYPE A,
SYNAPTOSOMAL-ASSOCIA
TED PROTEIN 23


(Clostridium
botulinum;
Homo sapiens)
PF01742
(Peptidase_M27)
PF07952
(Toxin_trans)
5 LEU A 225
LEU A 107
ILE A 111
GLU A 148
PHE A   3
None
1.04A 4y0rA-3zusA:
undetectable
4y0rA-3zusA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b0a TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 1,
LINKER,
TATA-BOX-BINDING
PROTEIN


(Saccharomyces
cerevisiae)
PF00352
(TBP)
5 ILE A 270
LEU A 275
ILE A 306
ILE A 312
VAL A 266
None
0.84A 4y0rA-4b0aA:
2.0
4y0rA-4b0aA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bub UDP-N-ACETYLMURAMOYL
-L-ALANYL-D-GLUTAMAT
E--LD-LYSINE LIGASE


(Thermotoga
maritima)
PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M)
5 LEU A 125
LEU A 304
ILE A 121
ILE A 197
VAL A 195
None
0.90A 4y0rA-4bubA:
undetectable
4y0rA-4bubA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d86 POLY [ADP-RIBOSE]
POLYMERASE 14


(Homo sapiens)
PF01661
(Macro)
5 LEU A 804
LEU A 959
ILE A 957
LEU A 954
ILE A 916
None
1.02A 4y0rA-4d86A:
undetectable
4y0rA-4d86A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1


(Arabidopsis
thaliana)
PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8)
5 LEU A 455
ILE A 431
LEU A 428
ILE A 407
VAL A 418
None
0.70A 4y0rA-4j0mA:
undetectable
4y0rA-4j0mA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jbu VIRULENCE-ASSOCIATED
V ANTIGEN


(Yersinia pestis)
PF04792
(LcrV)
5 VAL A 284
LEU A 193
ILE A 236
ILE A 186
ILE A 184
None
0.82A 4y0rA-4jbuA:
undetectable
4y0rA-4jbuA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lid A-100

(Sulfolobus
spindle-shaped
virus 1)
PF17639
(DUF5517)
5 LEU A  57
LEU A  61
ILE A  94
LEU A  95
ILE A  91
None
0.90A 4y0rA-4lidA:
undetectable
4y0rA-4lidA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mmo SSO-CP2
METALLO-CARBOXYPETID
ASE


(Sulfolobus
solfataricus)
PF01546
(Peptidase_M20)
PF07687
(M20_dimer)
5 LEU A 131
ILE A  68
LEU A  66
ILE A 161
ILE A 399
None
0.65A 4y0rA-4mmoA:
undetectable
4y0rA-4mmoA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nzr PROTEIN M TD

(Mycoplasma
genitalium)
no annotation 5 LEU M 292
LEU M 271
ILE M 268
LEU M 266
ILE M 246
None
0.73A 4y0rA-4nzrM:
undetectable
4y0rA-4nzrM:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q22 GLYCOSIDE HYDROLASE
FAMILY 18


(Serratia
proteamaculans)
PF00704
(Glyco_hydro_18)
5 LEU A 269
LEU A 219
ILE A 217
LEU A 214
ILE A 192
None
0.73A 4y0rA-4q22A:
undetectable
4y0rA-4q22A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q66 PROTEIN BCH1

(Saccharomyces
cerevisiae)
no annotation 5 LEU K 327
ILE K 323
ILE K 307
VAL K 303
PHE K 333
None
0.86A 4y0rA-4q66K:
undetectable
4y0rA-4q66K:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qb9 ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN


(Mycolicibacterium
smegmatis)
PF13527
(Acetyltransf_9)
PF13530
(SCP2_2)
5 VAL A 355
LEU A 303
LEU A 331
LEU A 359
ILE A 349
None
0.97A 4y0rA-4qb9A:
1.8
4y0rA-4qb9A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qj4 1-PHOSPHATIDYLINOSIT
OL 4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-3


(Homo sapiens)
PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like)
5 VAL B 672
LEU B 674
GLU B 622
VAL B 689
PHE B 690
None
1.04A 4y0rA-4qj4B:
undetectable
4y0rA-4qj4B:
12.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4r0b GLYCODELIN

(Homo sapiens)
PF00061
(Lipocalin)
7 VAL A  41
LEU A  46
LEU A  54
ILE A  56
LEU A  58
GLU A  62
ILE A  84
None
0.71A 4y0rA-4r0bA:
21.5
4y0rA-4r0bA:
41.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4r0b GLYCODELIN

(Homo sapiens)
PF00061
(Lipocalin)
5 VAL A  41
LEU A  54
LEU A  58
GLU A  62
LYS A  69
None
0.78A 4y0rA-4r0bA:
21.5
4y0rA-4r0bA:
41.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uy9 MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 9


(Homo sapiens)
PF00069
(Pkinase)
5 ILE A 249
LEU A 338
ILE A 274
ILE A 292
PHE A 396
None
0.86A 4y0rA-4uy9A:
undetectable
4y0rA-4uy9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xup ENDO-1,4-BETA-XYLANA
SE C


(Paenibacillus
barcinonensis)
PF02018
(CBM_4_9)
5 LEU A 173
ILE A 329
ILE A 236
ILE A 288
VAL A 290
None
1.00A 4y0rA-4xupA:
undetectable
4y0rA-4xupA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xut ENDO-1,4-BETA-XYLANA
SE C


(Paenibacillus
barcinonensis)
PF02018
(CBM_4_9)
5 LEU A 173
ILE A 329
ILE A 236
ILE A 288
VAL A 290
None
0.99A 4y0rA-4xutA:
undetectable
4y0rA-4xutA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z0c TOLL-LIKE RECEPTOR
13


(Mus musculus)
PF00560
(LRR_1)
PF13516
(LRR_6)
PF13855
(LRR_8)
5 LEU A 203
LEU A 205
LEU A 156
ILE A 163
VAL A 166
None
None
None
NAG  A 904 ( 4.2A)
None
0.92A 4y0rA-4z0cA:
undetectable
4y0rA-4z0cA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c1b TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE


(Homo sapiens)
PF00004
(AAA)
PF02359
(CDC48_N)
PF02933
(CDC48_2)
PF09336
(Vps4_C)
5 LEU A 306
ILE A 303
GLU A 292
ILE A 269
ILE A 274
None
0.94A 4y0rA-5c1bA:
undetectable
4y0rA-5c1bA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c1e PECTINESTERASE

(Aspergillus
niger)
PF01095
(Pectinesterase)
5 VAL A 122
LEU A  77
ILE A  50
PHE A 129
MET A 131
None
0.87A 4y0rA-5c1eA:
undetectable
4y0rA-5c1eA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e6g DE NOVO DESIGNED
PROTEIN CA01


(synthetic
construct)
no annotation 6 LEU A  88
LEU A  12
ILE A   8
ILE A  58
VAL A  62
PHE A  81
None
1.34A 4y0rA-5e6gA:
undetectable
4y0rA-5e6gA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fz5 TATA-BOX-BINDING
PROTEIN


(Saccharomyces
cerevisiae)
PF00352
(TBP)
5 ILE O 170
LEU O 175
ILE O 206
ILE O 212
VAL O 166
None
0.80A 4y0rA-5fz5O:
undetectable
4y0rA-5fz5O:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzt CHITINASE

(Paenibacillus
sp. FPU-7)
PF00704
(Glyco_hydro_18)
5 LEU B 809
LEU B 763
ILE B 761
LEU B 758
ILE B 737
None
0.73A 4y0rA-5gztB:
undetectable
4y0rA-5gztB:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzu CHITINASE

(Paenibacillus
sp. FPU-7)
PF00704
(Glyco_hydro_18)
5 LEU A 809
LEU A 763
ILE A 761
LEU A 758
ILE A 737
None
0.75A 4y0rA-5gzuA:
undetectable
4y0rA-5gzuA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihr PROBABLE
BETA-GALACTOSIDASE A


(Aspergillus
niger)
PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5)
5 LEU A 503
LEU A 560
ILE A 562
LEU A 564
ILE A 555
None
0.74A 4y0rA-5ihrA:
undetectable
4y0rA-5ihrA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lkm DNA REPAIR PROTEIN
RADA


(Streptococcus
pneumoniae)
PF13481
(AAA_25)
PF13541
(ChlI)
5 VAL A 193
LEU A  92
ILE A 210
LEU A 197
ILE A 169
None
0.89A 4y0rA-5lkmA:
undetectable
4y0rA-5lkmA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m4y EXOCYST COMPLEX
COMPONENT SEC3


(Saccharomyces
cerevisiae)
PF15277
(Sec3-PIP2_bind)
5 LEU B 172
ILE B 153
LEU B 139
GLU B 116
LYS B 155
None
1.06A 4y0rA-5m4yB:
undetectable
4y0rA-5m4yB:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzh DYNEIN ASSEMBLY
FACTOR WITH WDR
REPEAT DOMAINS 1


(Chlamydomonas
reinhardtii)
PF00400
(WD40)
5 ILE A  17
LEU A  19
LYS A  30
ILE A  32
ILE A  50
None
1.02A 4y0rA-5mzhA:
undetectable
4y0rA-5mzhA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6u BETA-MANNOSIDASE

(Dictyoglomus
thermophilum)
PF00703
(Glyco_hydro_2)
PF02837
(Glyco_hydro_2_N)
5 LEU A 247
ILE A 249
LEU A 251
ILE A 207
VAL A 221
None
1.03A 4y0rA-5n6uA:
undetectable
4y0rA-5n6uA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN


(Trichoplax
adhaerens)
no annotation 5 VAL A 186
LEU A  74
ILE A  84
LEU A 165
ILE A  38
None
1.03A 4y0rA-5oi9A:
undetectable
4y0rA-5oi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oko PHOSPHATIDYLINOSITOL
3,4,5-TRISPHOSPHATE
5-PHOSPHATASE 2


(Homo sapiens)
PF03372
(Exo_endo_phos)
5 LEU A 631
LEU A 612
ILE A 619
LEU A 620
ILE A 616
None
1.03A 4y0rA-5okoA:
undetectable
4y0rA-5okoA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5osn CAPSID PROTEIN

(Enterovirus E)
PF00073
(Rhv)
5 LEU A 213
ILE A  90
VAL A 175
PHE A 114
MET A 112
SPH  A 301 (-4.6A)
SPH  A 301 (-4.1A)
SPH  A 301 (-4.9A)
SPH  A 301 ( 4.2A)
SPH  A 301 ( 4.2A)
0.99A 4y0rA-5osnA:
undetectable
4y0rA-5osnA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ws4 MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB


(Acinetobacter
baumannii)
no annotation 5 LEU A  38
ILE A 199
LEU A 192
ILE A 168
ILE A  93
None
0.87A 4y0rA-5ws4A:
undetectable
4y0rA-5ws4A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yq5 OSTEOMODULIN

(Homo sapiens)
no annotation 5 LEU A 146
ILE A 120
LEU A 117
ILE A  86
VAL A 106
None
0.70A 4y0rA-5yq5A:
undetectable
4y0rA-5yq5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yq5 OSTEOMODULIN

(Homo sapiens)
no annotation 5 LEU A 146
LEU A 148
LEU A  96
ILE A 103
VAL A 106
None
1.01A 4y0rA-5yq5A:
undetectable
4y0rA-5yq5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6q EXOSOME RNA HELICASE
MTR4


(Homo sapiens)
no annotation 5 VAL M 441
LEU M1040
ILE M 462
LEU M 463
ILE M1034
None
1.07A 4y0rA-6d6qM:
undetectable
4y0rA-6d6qM:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fnw VOLUME-REGULATED
ANION CHANNEL
SUBUNIT LRRC8A


(Mus musculus)
no annotation 5 VAL A 442
LEU A 474
LEU A 476
ILE A 456
VAL A 459
None
0.80A 4y0rA-6fnwA:
undetectable
4y0rA-6fnwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g9o VOLUME-REGULATED
ANION CHANNEL
SUBUNIT LRRC8A


(Mus musculus)
no annotation 5 VAL A 442
LEU A 474
LEU A 476
ILE A 456
VAL A 459
None
0.80A 4y0rA-6g9oA:
undetectable
4y0rA-6g9oA:
undetectable