SIMILAR PATTERNS OF AMINO ACIDS FOR 4Y0R_A_PX9A201
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bvw | PROTEIN(CELLOBIOHYDROLASEII) (Humicolainsolens) |
PF01341(Glyco_hydro_6) | 5 | LEU A 148LEU A 138ILE A 207ILE A 204MET A 265 | None | 0.88A | 4y0rA-1bvwA:0.0 | 4y0rA-1bvwA:17.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1exs | BETA-LACTOGLOBULIN (Sus scrofa) |
PF00061(Lipocalin) | 5 | LEU A 46LEU A 54ILE A 56LEU A 58ILE A 84 | None | 0.62A | 4y0rA-1exsA:14.9 | 4y0rA-1exsA:64.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ezv | UBIQUINOL-CYTOCHROMEC REDUCTASE COMPLEXCORE PROTEIN I (Saccharomycescerevisiae) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 5 | LEU A 342ILE A 343LEU A 347ILE A 447ILE A 432 | None | 0.91A | 4y0rA-1ezvA:1.4 | 4y0rA-1ezvA:17.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gtk | PORPHOBILINOGENDEAMINASE (Escherichiacoli) |
PF01379(Porphobil_deam)PF03900(Porphobil_deamC) | 5 | LEU A 38ILE A 8LEU A 6ILE A 77ILE A 203 | None | 0.85A | 4y0rA-1gtkA:undetectable | 4y0rA-1gtkA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j1v | CHROMOSOMALREPLICATIONINITIATOR PROTEINDNAA (Escherichiacoli) |
PF08299(Bac_DnaA_C) | 5 | LEU A 465LEU A 417ILE A 379ILE A 376ILE A 425 | None | 1.03A | 4y0rA-1j1vA:undetectable | 4y0rA-1j1vA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jfl | ASPARTATE RACEMASE (Pyrococcushorikoshii) |
PF01177(Asp_Glu_race) | 5 | LEU A 206LEU A 210ILE A 190LEU A 182VAL A 197 | None | 0.95A | 4y0rA-1jflA:undetectable | 4y0rA-1jflA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ktw | IOTA-CARRAGEENASE (Alteromonas sp.ATCC 43554) |
PF12708(Pectate_lyase_3) | 5 | VAL A 161LEU A 69LEU A 126VAL A 107PHE A 140 | None | 1.05A | 4y0rA-1ktwA:0.0 | 4y0rA-1ktwA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mor | GLUCOSAMINE6-PHOSPHATE SYNTHASE (Escherichiacoli) |
PF01380(SIS) | 5 | LEU A 371LEU A 342ILE A 344LEU A 346ILE A 297 | None | 0.83A | 4y0rA-1morA:0.1 | 4y0rA-1morA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vi1 | FATTYACID/PHOSPHOLIPIDSYNTHESIS PROTEINPLSX (Bacillussubtilis) |
PF02504(FA_synthesis) | 5 | LEU A 35ILE A 33LEU A 31ILE A 3ILE A 96 | None | 0.92A | 4y0rA-1vi1A:undetectable | 4y0rA-1vi1A:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vtl | TATA BINDING PROTEIN(TBP) (Arabidopsisthaliana) |
PF00352(TBP) | 5 | ILE E 128LEU E 133ILE E 164ILE E 170VAL E 124 | None | 0.81A | 4y0rA-1vtlE:3.5 | 4y0rA-1vtlE:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xg2 | PECTINESTERASE 1 (Solanumlycopersicum) |
PF01095(Pectinesterase) | 5 | LEU A 94ILE A 57LEU A 55ILE A 35VAL A 46 | None | 1.07A | 4y0rA-1xg2A:undetectable | 4y0rA-1xg2A:16.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xg2 | PECTINESTERASE 1 (Solanumlycopersicum) |
PF01095(Pectinesterase) | 5 | VAL A 46LEU A 85ILE A 57ILE A 35VAL A 7 | None | 1.02A | 4y0rA-1xg2A:undetectable | 4y0rA-1xg2A:16.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xm7 | HYPOTHETICAL PROTEINAQ_1665 (Aquifexaeolicus) |
PF12850(Metallophos_2) | 5 | LEU A 109ILE A 142LEU A 140ILE A 165ILE A 177 | None | 0.75A | 4y0rA-1xm7A:undetectable | 4y0rA-1xm7A:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xm7 | HYPOTHETICAL PROTEINAQ_1665 (Aquifexaeolicus) |
PF12850(Metallophos_2) | 5 | LEU A 109LEU A 48ILE A 142LEU A 140ILE A 177 | None | 0.96A | 4y0rA-1xm7A:undetectable | 4y0rA-1xm7A:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xm7 | HYPOTHETICAL PROTEINAQ_1665 (Aquifexaeolicus) |
PF12850(Metallophos_2) | 5 | LEU A 140ILE A 107LEU A 109LYS A 98ILE A 100 | None | 0.90A | 4y0rA-1xm7A:undetectable | 4y0rA-1xm7A:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yq2 | BETA-GALACTOSIDASE (Arthrobactersp. C2-2) |
PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N)PF16353(DUF4981) | 5 | LEU A 935LEU A 933LEU A 752ILE A1020VAL A 987 | None | 0.87A | 4y0rA-1yq2A:undetectable | 4y0rA-1yq2A:10.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dgx | KIAA0430 PROTEIN (Homo sapiens) |
PF00076(RRM_1) | 5 | VAL A 602LEU A 598ILE A 562ILE A 627ILE A 622 | None | 0.79A | 4y0rA-2dgxA:undetectable | 4y0rA-2dgxA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e87 | HYPOTHETICAL PROTEINPH1320 (Pyrococcushorikoshii) |
PF06858(NOG1) | 5 | LEU A 284LEU A 249ILE A 251ILE A 172ILE A 218 | None | 0.80A | 4y0rA-2e87A:undetectable | 4y0rA-2e87A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hzs | RNA POLYMERASE IIMEDIATOR COMPLEXSUBUNIT 20 (Saccharomycescerevisiae) |
PF08612(Med20) | 5 | LEU A 139LEU A 151ILE A 153GLU A 164ILE A 7 | None | 0.95A | 4y0rA-2hzsA:1.8 | 4y0rA-2hzsA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j6h | GLUCOSAMINE-FRUCTOSE-6-PHOSPHATEAMINOTRANSFERASE (Escherichiacoli) |
PF01380(SIS)PF13522(GATase_6) | 5 | LEU A 371LEU A 342ILE A 344LEU A 346ILE A 297 | None | 0.82A | 4y0rA-2j6hA:undetectable | 4y0rA-2j6hA:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jaq | DEOXYGUANOSINEKINASE (Mycoplasmamycoides) |
PF01712(dNK) | 5 | VAL A 181ILE A 5LEU A 131ILE A 16ILE A 20 | None | 0.93A | 4y0rA-2jaqA:undetectable | 4y0rA-2jaqA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jcs | DEOXYNUCLEOSIDEKINASE (Drosophilamelanogaster) |
PF01712(dNK) | 5 | LEU A 203LEU A 149ILE A 151ILE A 25ILE A 102 | None | 0.66A | 4y0rA-2jcsA:undetectable | 4y0rA-2jcsA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jcs | DEOXYNUCLEOSIDEKINASE (Drosophilamelanogaster) |
PF01712(dNK) | 5 | LEU A 203LEU A 149ILE A 151LEU A 153ILE A 25 | None | 0.89A | 4y0rA-2jcsA:undetectable | 4y0rA-2jcsA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ocp | DEOXYGUANOSINEKINASE (Homo sapiens) |
PF01712(dNK) | 5 | LEU A 248ILE A 190LEU A 192ILE A 43ILE A 139 | None | 1.01A | 4y0rA-2ocpA:undetectable | 4y0rA-2ocpA:24.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ok8 | PUTATIVEFERREDOXIN--NADPREDUCTASE (Plasmodiumfalciparum) |
PF00175(NAD_binding_1) | 5 | LEU A 114ILE A 40LEU A 38LYS A 23ILE A 20 | None | 1.01A | 4y0rA-2ok8A:undetectable | 4y0rA-2ok8A:17.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ow4 | CANAVALIA MARITIMALECTIN (Canavalia rosea) |
PF00139(Lectin_legB) | 5 | VAL A 65LEU A 93LEU A 156ILE A 210ILE A 199 | None | 0.95A | 4y0rA-2ow4A:undetectable | 4y0rA-2ow4A:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pyy | IONOTROPIC GLUTAMATERECEPTOR BACTERIALHOMOLOGUE (Nostocpunctiforme) |
PF00497(SBP_bac_3) | 5 | VAL A 7ILE A 186LEU A 64ILE A 198ILE A 34 | None | 0.90A | 4y0rA-2pyyA:undetectable | 4y0rA-2pyyA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qby | CELL DIVISIONCONTROL PROTEIN 6HOMOLOG 1 (Sulfolobussolfataricus) |
PF09079(Cdc6_C)PF13401(AAA_22) | 5 | VAL A 144ILE A 61ILE A 59ILE A 43VAL A 72 | None | 1.00A | 4y0rA-2qbyA:undetectable | 4y0rA-2qbyA:16.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v1u | CELL DIVISIONCONTROL PROTEIN 6HOMOLOG (Aeropyrumpernix) |
PF09079(Cdc6_C)PF13191(AAA_16) | 5 | LEU A 182LEU A 148ILE A 146LYS A 92ILE A 94 | None | 0.81A | 4y0rA-2v1uA:undetectable | 4y0rA-2v1uA:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vvf | MAJOR CAPSID PROTEINP2 (Pseudoalteromonasvirus PM2) |
no annotation | 5 | LEU A 23LEU A 7ILE A 21ILE A 10PHE A 83 | None | 0.96A | 4y0rA-2vvfA:undetectable | 4y0rA-2vvfA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ywm | GLUTAREDOXIN-LIKEPROTEIN (Aquifexaeolicus) |
PF13192(Thioredoxin_3) | 5 | LEU A 14ILE A 110LEU A 109ILE A 113ILE A 51 | None | 0.86A | 4y0rA-2ywmA:undetectable | 4y0rA-2ywmA:24.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zay | RESPONSE REGULATORRECEIVER PROTEIN (Desulfuromonasacetoxidans) |
PF00072(Response_reg) | 5 | LEU A 13ILE A 57ILE A 86ILE A 109VAL A 113 | None | 0.84A | 4y0rA-2zayA:undetectable | 4y0rA-2zayA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zay | RESPONSE REGULATORRECEIVER PROTEIN (Desulfuromonasacetoxidans) |
PF00072(Response_reg) | 5 | LEU A 13ILE A 57LEU A 55ILE A 86ILE A 109 | None | 1.06A | 4y0rA-2zayA:undetectable | 4y0rA-2zayA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a1z | HEMOLYMPH JUVENILEHORMONE BINDINGPROTEIN (Bombyx mori) |
PF06585(JHBP) | 5 | VAL A 122LEU A 48ILE A 196ILE A 97ILE A 67 | None | 1.06A | 4y0rA-3a1zA:undetectable | 4y0rA-3a1zA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3brq | HTH-TYPETRANSCRIPTIONALREGULATOR ASCG (Escherichiacoli) |
PF13377(Peripla_BP_3) | 5 | ILE A 91LEU A 86GLU A 62ILE A 94ILE A 102 | None | 0.86A | 4y0rA-3brqA:undetectable | 4y0rA-3brqA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3crw | XPD/RAD3 RELATED DNAHELICASE (Sulfolobusacidocaldarius) |
PF06733(DEAD_2)PF13307(Helicase_C_2) | 5 | LEU 1 24LEU 1 320ILE 1 318LEU 1 316ILE 1 177 | None | 1.00A | 4y0rA-3crw1:undetectable | 4y0rA-3crw1:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dtc | MITOGEN-ACTIVATEDPROTEIN KINASEKINASE KINASE 9 (Homo sapiens) |
PF07714(Pkinase_Tyr) | 5 | ILE A 249LEU A 338ILE A 274ILE A 292PHE A 396 | None | 1.04A | 4y0rA-3dtcA:undetectable | 4y0rA-3dtcA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fxq | LYSR TYPE REGULATOROF TSAMBCD (Comamonastestosteroni) |
PF00126(HTH_1)PF03466(LysR_substrate) | 5 | LEU A 265ILE A 170LEU A 239ILE A 259PHE A 209 | None | 0.88A | 4y0rA-3fxqA:undetectable | 4y0rA-3fxqA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1l | CYTOCHROME B (Gallus gallus) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 5 | VAL C 299LEU C 302ILE C 99ILE C 95MET C 125 | NoneHEM C 502 ( 4.9A)HEM C 502 (-3.9A)None3H1 C2001 ( 4.7A) | 0.82A | 4y0rA-3h1lC:undetectable | 4y0rA-3h1lC:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hcw | MALTOSE OPERONTRANSCRIPTIONALREPRESSOR (Staphylococcusaureus) |
PF13377(Peripla_BP_3) | 5 | LEU A 64LEU A 127ILE A 125ILE A 147ILE A 163 | None | 0.68A | 4y0rA-3hcwA:undetectable | 4y0rA-3hcwA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i0m | DNA REPAIR ANDTELOMERE MAINTENANCEPROTEIN NBS1 (Schizosaccharomycespombe) |
PF00498(FHA) | 5 | LEU A 98ILE A 100LEU A 102ILE A 109ILE A 4 | None | 0.98A | 4y0rA-3i0mA:undetectable | 4y0rA-3i0mA:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i4t | DIPHTHINE SYNTHASE (Entamoebahistolytica) |
PF00590(TP_methylase) | 5 | LEU A 80LEU A 7ILE A 5LYS A 106ILE A 108 | None | 0.65A | 4y0rA-3i4tA:undetectable | 4y0rA-3i4tA:21.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kza | BETA-LACTOGLOBULIN (Equus caballus;Bos taurus) |
PF00061(Lipocalin) | 7 | VAL A 41LEU A 46LEU A 54ILE A 56ILE A 84VAL A 92PHE A 105 | None | 0.59A | 4y0rA-3kzaA:24.9 | 4y0rA-3kzaA:81.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kza | BETA-LACTOGLOBULIN (Equus caballus;Bos taurus) |
PF00061(Lipocalin) | 7 | VAL A 41LEU A 46LEU A 54ILE A 56LEU A 58ILE A 71ILE A 84 | None | 0.72A | 4y0rA-3kzaA:24.9 | 4y0rA-3kzaA:81.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kza | BETA-LACTOGLOBULIN (Equus caballus;Bos taurus) |
PF00061(Lipocalin) | 6 | VAL A 41LEU A 46LEU A 54VAL A 92PHE A 105MET A 107 | None | 0.48A | 4y0rA-3kzaA:24.9 | 4y0rA-3kzaA:81.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n6u | LYSR TYPE REGULATOROF TSAMBCD (Comamonastestosteroni) |
PF03466(LysR_substrate) | 5 | LEU A 265ILE A 170LEU A 239ILE A 259PHE A 209 | None | 0.87A | 4y0rA-3n6uA:undetectable | 4y0rA-3n6uA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o5y | SENSOR PROTEIN (Bacillushalodurans) |
PF13492(GAF_3) | 5 | LEU A 102ILE A 118LEU A 116ILE A 30VAL A 25 | None | 0.81A | 4y0rA-3o5yA:undetectable | 4y0rA-3o5yA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3odp | PUTATIVETAGATOSE-6-PHOSPHATEKETOSE/ALDOSEISOMERASE (Clostridiumnovyi) |
PF01380(SIS) | 5 | LEU A 163LEU A 140ILE A 142GLU A 246ILE A 62 | None | 0.81A | 4y0rA-3odpA:undetectable | 4y0rA-3odpA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ouk | PROBABLE CONSERVEDTRANSMEMBRANEPROTEIN (Mycobacteriumtuberculosis) |
no annotation | 5 | VAL A 164LEU A 252ILE A 184LEU A 134ILE A 150 | None | 0.94A | 4y0rA-3oukA:undetectable | 4y0rA-3oukA:21.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ph5 | BETA-LACTOGLOBULIN (Bos taurus) |
PF00061(Lipocalin) | 7 | VAL A 57LEU A 62GLU A 78LYS A 85VAL A 108PHE A 121MET A 123 | None | 0.84A | 4y0rA-3ph5A:28.7 | 4y0rA-3ph5A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ph5 | BETA-LACTOGLOBULIN (Bos taurus) |
PF00061(Lipocalin) | 7 | VAL A 57LEU A 62LEU A 70GLU A 78LYS A 85VAL A 108PHE A 121 | None | 0.72A | 4y0rA-3ph5A:28.7 | 4y0rA-3ph5A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ph5 | BETA-LACTOGLOBULIN (Bos taurus) |
PF00061(Lipocalin) | 8 | VAL A 57LEU A 62LEU A 70ILE A 72LEU A 74GLU A 78ILE A 87ILE A 100 | None | 0.64A | 4y0rA-3ph5A:28.7 | 4y0rA-3ph5A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ph5 | BETA-LACTOGLOBULIN (Bos taurus) |
PF00061(Lipocalin) | 9 | VAL A 57LEU A 62LEU A 70ILE A 72LEU A 74GLU A 78ILE A 100VAL A 108PHE A 121 | None | 0.66A | 4y0rA-3ph5A:28.7 | 4y0rA-3ph5A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q6z | POLY [ADP-RIBOSE]POLYMERASE 14 (Homo sapiens) |
PF01661(Macro) | 5 | LEU A 804LEU A 959ILE A 957LEU A 954ILE A 916 | None | 1.06A | 4y0rA-3q6zA:undetectable | 4y0rA-3q6zA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3trr | PROBABLE ENOYL-COAHYDRATASE/ISOMERASE (Mycobacteroidesabscessus) |
PF00378(ECH_1) | 5 | LEU A 14ILE A 16LEU A 35ILE A 53ILE A 92 | None | 1.03A | 4y0rA-3trrA:undetectable | 4y0rA-3trrA:25.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3up6 | HYPOTHETICAL PROTEINBACOVA_04078 (Bacteroidesovatus) |
no annotation | 5 | LEU A 43ILE A 41LEU A 39LYS A 167ILE A 156 | None | 0.93A | 4y0rA-3up6A:undetectable | 4y0rA-3up6A:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vom | PUTATIVEPHOSPHOSERINEAMINOTRANSFERASE (Mycobacteriumtuberculosis) |
PF00266(Aminotran_5) | 5 | VAL A 162LEU A 274LEU A 68ILE A 188ILE A 212 | None | 0.89A | 4y0rA-3vomA:undetectable | 4y0rA-3vomA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wvs | PUTATIVEMONOOXYGENASE (Streptomycessp. SN-593) |
PF00067(p450) | 5 | LEU A 232ILE A 197GLU A 163ILE A 200ILE A 213 | None | 1.02A | 4y0rA-3wvsA:undetectable | 4y0rA-3wvsA:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zdf | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Thermosynechococcuselongatus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 5 | LEU A 121LEU A 95ILE A 97ILE A 6ILE A 31 | None | 0.58A | 4y0rA-3zdfA:undetectable | 4y0rA-3zdfA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zhn | PA_0080 (Pseudomonasaeruginosa) |
PF12790(T6SS-SciN) | 5 | LEU A 16LEU A 125ILE A 123LEU A 121ILE A 132 | None | 0.81A | 4y0rA-3zhnA:undetectable | 4y0rA-3zhnA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zq4 | RIBONUCLEASE J 1 (Bacillussubtilis) |
PF00753(Lactamase_B)PF07521(RMMBL) | 5 | VAL A 515LEU A 507ILE A 508LEU A 512ILE A 530 | None | 1.05A | 4y0rA-3zq4A:1.4 | 4y0rA-3zq4A:15.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zus | BOTULINUM NEUROTOXINTYPE A,SYNAPTOSOMAL-ASSOCIATED PROTEIN 23 (Clostridiumbotulinum;Homo sapiens) |
PF01742(Peptidase_M27)PF07952(Toxin_trans) | 5 | LEU A 225LEU A 107ILE A 111GLU A 148PHE A 3 | None | 1.04A | 4y0rA-3zusA:undetectable | 4y0rA-3zusA:10.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b0a | TRANSCRIPTIONINITIATION FACTORTFIID SUBUNIT 1,LINKER,TATA-BOX-BINDINGPROTEIN (Saccharomycescerevisiae) |
PF00352(TBP) | 5 | ILE A 270LEU A 275ILE A 306ILE A 312VAL A 266 | None | 0.84A | 4y0rA-4b0aA:2.0 | 4y0rA-4b0aA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bub | UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--LD-LYSINE LIGASE (Thermotogamaritima) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 5 | LEU A 125LEU A 304ILE A 121ILE A 197VAL A 195 | None | 0.90A | 4y0rA-4bubA:undetectable | 4y0rA-4bubA:15.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d86 | POLY [ADP-RIBOSE]POLYMERASE 14 (Homo sapiens) |
PF01661(Macro) | 5 | LEU A 804LEU A 959ILE A 957LEU A 954ILE A 916 | None | 1.02A | 4y0rA-4d86A:undetectable | 4y0rA-4d86A:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j0m | SERINE/THREONINE-PROTEIN KINASEBRI1-LIKE 1 (Arabidopsisthaliana) |
PF08263(LRRNT_2)PF13516(LRR_6)PF13855(LRR_8) | 5 | LEU A 455ILE A 431LEU A 428ILE A 407VAL A 418 | None | 0.70A | 4y0rA-4j0mA:undetectable | 4y0rA-4j0mA:11.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jbu | VIRULENCE-ASSOCIATEDV ANTIGEN (Yersinia pestis) |
PF04792(LcrV) | 5 | VAL A 284LEU A 193ILE A 236ILE A 186ILE A 184 | None | 0.82A | 4y0rA-4jbuA:undetectable | 4y0rA-4jbuA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lid | A-100 (Sulfolobusspindle-shapedvirus 1) |
PF17639(DUF5517) | 5 | LEU A 57LEU A 61ILE A 94LEU A 95ILE A 91 | None | 0.90A | 4y0rA-4lidA:undetectable | 4y0rA-4lidA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mmo | SSO-CP2METALLO-CARBOXYPETIDASE (Sulfolobussolfataricus) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | LEU A 131ILE A 68LEU A 66ILE A 161ILE A 399 | None | 0.65A | 4y0rA-4mmoA:undetectable | 4y0rA-4mmoA:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nzr | PROTEIN M TD (Mycoplasmagenitalium) |
no annotation | 5 | LEU M 292LEU M 271ILE M 268LEU M 266ILE M 246 | None | 0.73A | 4y0rA-4nzrM:undetectable | 4y0rA-4nzrM:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q22 | GLYCOSIDE HYDROLASEFAMILY 18 (Serratiaproteamaculans) |
PF00704(Glyco_hydro_18) | 5 | LEU A 269LEU A 219ILE A 217LEU A 214ILE A 192 | None | 0.73A | 4y0rA-4q22A:undetectable | 4y0rA-4q22A:17.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q66 | PROTEIN BCH1 (Saccharomycescerevisiae) |
no annotation | 5 | LEU K 327ILE K 323ILE K 307VAL K 303PHE K 333 | None | 0.86A | 4y0rA-4q66K:undetectable | 4y0rA-4q66K:12.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qb9 | ENHANCEDINTRACELLULARSURVIVAL PROTEIN (Mycolicibacteriumsmegmatis) |
PF13527(Acetyltransf_9)PF13530(SCP2_2) | 5 | VAL A 355LEU A 303LEU A 331LEU A 359ILE A 349 | None | 0.97A | 4y0rA-4qb9A:1.8 | 4y0rA-4qb9A:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qj4 | 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATEPHOSPHODIESTERASEBETA-3 (Homo sapiens) |
PF00168(C2)PF00387(PI-PLC-Y)PF00388(PI-PLC-X)PF09279(EF-hand_like) | 5 | VAL B 672LEU B 674GLU B 622VAL B 689PHE B 690 | None | 1.04A | 4y0rA-4qj4B:undetectable | 4y0rA-4qj4B:12.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r0b | GLYCODELIN (Homo sapiens) |
PF00061(Lipocalin) | 7 | VAL A 41LEU A 46LEU A 54ILE A 56LEU A 58GLU A 62ILE A 84 | None | 0.71A | 4y0rA-4r0bA:21.5 | 4y0rA-4r0bA:41.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r0b | GLYCODELIN (Homo sapiens) |
PF00061(Lipocalin) | 5 | VAL A 41LEU A 54LEU A 58GLU A 62LYS A 69 | None | 0.78A | 4y0rA-4r0bA:21.5 | 4y0rA-4r0bA:41.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uy9 | MITOGEN-ACTIVATEDPROTEIN KINASEKINASE KINASE 9 (Homo sapiens) |
PF00069(Pkinase) | 5 | ILE A 249LEU A 338ILE A 274ILE A 292PHE A 396 | None | 0.86A | 4y0rA-4uy9A:undetectable | 4y0rA-4uy9A:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xup | ENDO-1,4-BETA-XYLANASE C (Paenibacillusbarcinonensis) |
PF02018(CBM_4_9) | 5 | LEU A 173ILE A 329ILE A 236ILE A 288VAL A 290 | None | 1.00A | 4y0rA-4xupA:undetectable | 4y0rA-4xupA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xut | ENDO-1,4-BETA-XYLANASE C (Paenibacillusbarcinonensis) |
PF02018(CBM_4_9) | 5 | LEU A 173ILE A 329ILE A 236ILE A 288VAL A 290 | None | 0.99A | 4y0rA-4xutA:undetectable | 4y0rA-4xutA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z0c | TOLL-LIKE RECEPTOR13 (Mus musculus) |
PF00560(LRR_1)PF13516(LRR_6)PF13855(LRR_8) | 5 | LEU A 203LEU A 205LEU A 156ILE A 163VAL A 166 | NoneNoneNoneNAG A 904 ( 4.2A)None | 0.92A | 4y0rA-4z0cA:undetectable | 4y0rA-4z0cA:12.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c1b | TRANSITIONALENDOPLASMICRETICULUM ATPASE (Homo sapiens) |
PF00004(AAA)PF02359(CDC48_N)PF02933(CDC48_2)PF09336(Vps4_C) | 5 | LEU A 306ILE A 303GLU A 292ILE A 269ILE A 274 | None | 0.94A | 4y0rA-5c1bA:undetectable | 4y0rA-5c1bA:12.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c1e | PECTINESTERASE (Aspergillusniger) |
PF01095(Pectinesterase) | 5 | VAL A 122LEU A 77ILE A 50PHE A 129MET A 131 | None | 0.87A | 4y0rA-5c1eA:undetectable | 4y0rA-5c1eA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e6g | DE NOVO DESIGNEDPROTEIN CA01 (syntheticconstruct) |
no annotation | 6 | LEU A 88LEU A 12ILE A 8ILE A 58VAL A 62PHE A 81 | None | 1.34A | 4y0rA-5e6gA:undetectable | 4y0rA-5e6gA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fz5 | TATA-BOX-BINDINGPROTEIN (Saccharomycescerevisiae) |
PF00352(TBP) | 5 | ILE O 170LEU O 175ILE O 206ILE O 212VAL O 166 | None | 0.80A | 4y0rA-5fz5O:undetectable | 4y0rA-5fz5O:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzt | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 5 | LEU B 809LEU B 763ILE B 761LEU B 758ILE B 737 | None | 0.73A | 4y0rA-5gztB:undetectable | 4y0rA-5gztB:9.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzu | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 5 | LEU A 809LEU A 763ILE A 761LEU A 758ILE A 737 | None | 0.75A | 4y0rA-5gzuA:undetectable | 4y0rA-5gzuA:11.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihr | PROBABLEBETA-GALACTOSIDASE A (Aspergillusniger) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 5 | LEU A 503LEU A 560ILE A 562LEU A 564ILE A 555 | None | 0.74A | 4y0rA-5ihrA:undetectable | 4y0rA-5ihrA:9.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lkm | DNA REPAIR PROTEINRADA (Streptococcuspneumoniae) |
PF13481(AAA_25)PF13541(ChlI) | 5 | VAL A 193LEU A 92ILE A 210LEU A 197ILE A 169 | None | 0.89A | 4y0rA-5lkmA:undetectable | 4y0rA-5lkmA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m4y | EXOCYST COMPLEXCOMPONENT SEC3 (Saccharomycescerevisiae) |
PF15277(Sec3-PIP2_bind) | 5 | LEU B 172ILE B 153LEU B 139GLU B 116LYS B 155 | None | 1.06A | 4y0rA-5m4yB:undetectable | 4y0rA-5m4yB:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mzh | DYNEIN ASSEMBLYFACTOR WITH WDRREPEAT DOMAINS 1 (Chlamydomonasreinhardtii) |
PF00400(WD40) | 5 | ILE A 17LEU A 19LYS A 30ILE A 32ILE A 50 | None | 1.02A | 4y0rA-5mzhA:undetectable | 4y0rA-5mzhA:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n6u | BETA-MANNOSIDASE (Dictyoglomusthermophilum) |
PF00703(Glyco_hydro_2)PF02837(Glyco_hydro_2_N) | 5 | LEU A 247ILE A 249LEU A 251ILE A 207VAL A 221 | None | 1.03A | 4y0rA-5n6uA:undetectable | 4y0rA-5n6uA:13.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oi9 | PUTATIVEUNCHARACTERIZEDPROTEIN (Trichoplaxadhaerens) |
no annotation | 5 | VAL A 186LEU A 74ILE A 84LEU A 165ILE A 38 | None | 1.03A | 4y0rA-5oi9A:undetectable | 4y0rA-5oi9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oko | PHOSPHATIDYLINOSITOL3,4,5-TRISPHOSPHATE5-PHOSPHATASE 2 (Homo sapiens) |
PF03372(Exo_endo_phos) | 5 | LEU A 631LEU A 612ILE A 619LEU A 620ILE A 616 | None | 1.03A | 4y0rA-5okoA:undetectable | 4y0rA-5okoA:17.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5osn | CAPSID PROTEIN (Enterovirus E) |
PF00073(Rhv) | 5 | LEU A 213ILE A 90VAL A 175PHE A 114MET A 112 | SPH A 301 (-4.6A)SPH A 301 (-4.1A)SPH A 301 (-4.9A)SPH A 301 ( 4.2A)SPH A 301 ( 4.2A) | 0.99A | 4y0rA-5osnA:undetectable | 4y0rA-5osnA:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ws4 | MACROLIDE EXPORTATP-BINDING/PERMEASEPROTEIN MACB (Acinetobacterbaumannii) |
no annotation | 5 | LEU A 38ILE A 199LEU A 192ILE A 168ILE A 93 | None | 0.87A | 4y0rA-5ws4A:undetectable | 4y0rA-5ws4A:14.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yq5 | OSTEOMODULIN (Homo sapiens) |
no annotation | 5 | LEU A 146ILE A 120LEU A 117ILE A 86VAL A 106 | None | 0.70A | 4y0rA-5yq5A:undetectable | 4y0rA-5yq5A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yq5 | OSTEOMODULIN (Homo sapiens) |
no annotation | 5 | LEU A 146LEU A 148LEU A 96ILE A 103VAL A 106 | None | 1.01A | 4y0rA-5yq5A:undetectable | 4y0rA-5yq5A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d6q | EXOSOME RNA HELICASEMTR4 (Homo sapiens) |
no annotation | 5 | VAL M 441LEU M1040ILE M 462LEU M 463ILE M1034 | None | 1.07A | 4y0rA-6d6qM:undetectable | 4y0rA-6d6qM:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fnw | VOLUME-REGULATEDANION CHANNELSUBUNIT LRRC8A (Mus musculus) |
no annotation | 5 | VAL A 442LEU A 474LEU A 476ILE A 456VAL A 459 | None | 0.80A | 4y0rA-6fnwA:undetectable | 4y0rA-6fnwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g9o | VOLUME-REGULATEDANION CHANNELSUBUNIT LRRC8A (Mus musculus) |
no annotation | 5 | VAL A 442LEU A 474LEU A 476ILE A 456VAL A 459 | None | 0.80A | 4y0rA-6g9oA:undetectable | 4y0rA-6g9oA:undetectable |