SIMILAR PATTERNS OF AMINO ACIDS FOR 4XV2_A_P06A801_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c3r HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN)

(Aquifex
aeolicus) 		PF00850
(Hist_deacetyl) 		4 GLY A 140
LEU A  69
PHE A 100
ILE A 144
 TSN  A 502 ( 3.9A)
None
None
None
 0.95A 4xv2A-1c3rA:
0.0		 4xv2A-1c3rA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1clx XYLANASE A

(Cellvibrio
japonicus) 		PF00331
(Glyco_hydro_10) 		4 GLY A  19
LEU A 331
PHE A 327
ILE A 307
 None
 0.97A 4xv2A-1clxA:
0.0		 4xv2A-1clxA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cy9 DNA TOPOISOMERASE I

(Escherichia
coli) 		PF01131
(Topoisom_bac) 		4 GLY A 315
LEU A 289
PHE A 284
ILE A 394
 None
 0.96A 4xv2A-1cy9A:
undetectable		 4xv2A-1cy9A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cyi CYTOCHROME C6

(Chlamydomonas
reinhardtii) 		PF13442
(Cytochrome_CBB3) 		4 GLY A  56
LEU A  36
PHE A  44
ILE A  49
 None
HEM  A 200 (-4.6A)
None
HEM  A 200 ( 4.3A)
 0.95A 4xv2A-1cyiA:
undetectable		 4xv2A-1cyiA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hw2 FATTY ACID
METABOLISM REGULATOR
PROTEIN

(Escherichia
coli) 		PF00392
(GntR)
PF07840
(FadR_C) 		4 GLY A 203
LEU A 152
PHE A 112
ILE A 113
 None
 0.92A 4xv2A-1hw2A:
1.8		 4xv2A-1hw2A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i9g HYPOTHETICAL PROTEIN
RV2118C

(Mycobacterium
tuberculosis) 		PF08704
(GCD14)
PF14801
(GCD14_N) 		4 GLY A  47
LEU A  15
PHE A  62
ILE A  40
 None
 0.91A 4xv2A-1i9gA:
0.0		 4xv2A-1i9gA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A

(Spinacia
oleracea) 		no annotation 4 GLY O  34
LEU O  16
PHE O  15
ILE O   5
 None
 0.94A 4xv2A-1jn0O:
0.0		 4xv2A-1jn0O:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k1d D-HYDANTOINASE

(Geobacillus
stearothermophilus) 		PF01979
(Amidohydro_1) 		4 GLY A  84
LEU A  61
PHE A  74
ILE A  89
 None
 0.87A 4xv2A-1k1dA:
0.0		 4xv2A-1k1dA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcx DIHYDROPYRIMIDINASE
RELATED PROTEIN-1

(Mus musculus) 		PF01979
(Amidohydro_1) 		4 GLY A  99
LEU A  76
PHE A  89
ILE A 104
 None
 0.86A 4xv2A-1kcxA:
0.0		 4xv2A-1kcxA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE

(Paraburkholderia
xenovorans) 		PF00903
(Glyoxalase) 		4 GLY A 143
LEU A  29
PHE A  41
ILE A  50
 None
 0.90A 4xv2A-1lkdA:
0.0		 4xv2A-1lkdA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 GLY A 165
LEU A 320
PHE A 307
ILE A 278
 None
 0.86A 4xv2A-1lnzA:
undetectable		 4xv2A-1lnzA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lox 15-LIPOXYGENASE

(Oryctolagus
cuniculus) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 GLY A  11
LEU A 109
PHE A  95
ILE A  81
 None
 0.92A 4xv2A-1loxA:
undetectable		 4xv2A-1loxA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mw9 DNA TOPOISOMERASE I

(Escherichia
coli) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 GLY X 315
LEU X 289
PHE X 284
ILE X 394
 None
 0.95A 4xv2A-1mw9X:
undetectable		 4xv2A-1mw9X:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n76 LACTOFERRIN

(Homo sapiens) 		PF00405
(Transferrin) 		4 GLY A 124
LEU A 320
PHE A 325
ILE A 328
 CO3  A 695 (-4.0A)
None
None
None
 0.97A 4xv2A-1n76A:
undetectable		 4xv2A-1n76A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p2f RESPONSE REGULATOR

(Thermotoga
maritima) 		PF00072
(Response_reg)
PF00486
(Trans_reg_C) 		4 GLY A 210
LEU A 157
PHE A 215
ILE A 205
 None
 0.98A 4xv2A-1p2fA:
undetectable		 4xv2A-1p2fA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pn4 PEROXISOMAL
HYDRATASE-DEHYDROGEN
ASE-EPIMERASE

(Candida
tropicalis) 		PF01575
(MaoC_dehydratas) 		4 GLY A 104
LEU A  63
PHE A  66
ILE A 133
 None
 0.98A 4xv2A-1pn4A:
undetectable		 4xv2A-1pn4A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q67 DECAPPING PROTEIN
INVOLVED IN MRNA
DEGRADATION-DCP1P

(Saccharomyces
cerevisiae) 		PF06058
(DCP1) 		4 GLY A  63
LEU A  37
PHE A  24
ILE A  27
 None
 0.70A 4xv2A-1q67A:
undetectable		 4xv2A-1q67A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qo8 FLAVOCYTOCHROME C3
FUMARATE REDUCTASE

(Shewanella
frigidimarina) 		PF00890
(FAD_binding_2)
PF14537
(Cytochrom_c3_2) 		4 GLY A 166
LEU A 256
PHE A 134
ILE A 253
 FAD  A 605 (-4.3A)
None
None
None
 0.91A 4xv2A-1qo8A:
undetectable		 4xv2A-1qo8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rz3 HYPOTHETICAL PROTEIN
RBSTP0775

(Geobacillus
stearothermophilus) 		PF00485
(PRK) 		4 GLY A  50
LEU A  25
PHE A 146
ILE A  14
 None
 0.95A 4xv2A-1rz3A:
undetectable		 4xv2A-1rz3A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sg9 HEMK PROTEIN

(Thermotoga
maritima) 		PF05175
(MTS) 		4 GLY A 136
LEU A 181
PHE A 188
ILE A 194
 None
 0.84A 4xv2A-1sg9A:
undetectable		 4xv2A-1sg9A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tp7 GENOME POLYPROTEIN

(Rhinovirus A) 		PF00680
(RdRP_1) 		4 GLY A 203
LEU A 194
PHE A 195
ILE A 294
 None
 0.98A 4xv2A-1tp7A:
undetectable		 4xv2A-1tp7A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tve HOMOSERINE
DEHYDROGENASE

(Saccharomyces
cerevisiae) 		PF00742
(Homoserine_dh)
PF03447
(NAD_binding_3) 		4 GLY A 289
LEU A 156
PHE A 155
ILE A 323
 None
 0.71A 4xv2A-1tveA:
undetectable		 4xv2A-1tveA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v4g GLUTAMATE--CYSTEINE
LIGASE

(Escherichia
coli) 		PF04262
(Glu_cys_ligase) 		4 GLY A 148
LEU A 350
PHE A 349
ILE A 194
 None
 0.74A 4xv2A-1v4gA:
0.9		 4xv2A-1v4gA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w7c LYSYL OXIDASE

(Komagataella
pastoris) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF09248
(DUF1965) 		4 GLY A 541
LEU A 492
PHE A 486
ILE A 364
 None
 0.91A 4xv2A-1w7cA:
undetectable		 4xv2A-1w7cA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1b CRTF-RELATED PROTEIN

(Chlorobaculum
tepidum) 		PF00891
(Methyltransf_2) 		4 GLY A  78
LEU A  35
PHE A  36
ILE A  73
 None
 0.82A 4xv2A-1x1bA:
undetectable		 4xv2A-1x1bA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y0g PROTEIN YCEI

(Escherichia
coli) 		PF04264
(YceI) 		4 GLY A  50
LEU A 127
PHE A 166
ILE A 161
 None
None
None
8PP  A 320 (-4.8A)
 0.86A 4xv2A-1y0gA:
undetectable		 4xv2A-1y0gA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yzv HYPOTHETICAL PROTEIN

(Trypanosoma
cruzi) 		PF00857
(Isochorismatase) 		4 GLY A  49
LEU A 173
PHE A 181
ILE A 184
 None
 0.99A 4xv2A-1yzvA:
undetectable		 4xv2A-1yzvA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zk7 MERCURIC REDUCTASE

(Pseudomonas
aeruginosa) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 GLY A  36
LEU A 276
PHE A 119
ILE A  10
 FAD  A 666 ( 4.6A)
None
None
FAD  A 666 (-4.7A)
 0.90A 4xv2A-1zk7A:
undetectable		 4xv2A-1zk7A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ak3 ADENYLATE KINASE
ISOENZYME-3

(Bos taurus) 		PF00406
(ADK)
PF05191
(ADK_lid) 		4 GLY A  19
LEU A 210
PHE A 209
ILE A 110
 SO4  A 227 (-3.3A)
None
None
None
 0.82A 4xv2A-2ak3A:
undetectable		 4xv2A-2ak3A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c4n PROTEIN NAGD

(Escherichia
coli) 		PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6) 		4 GLY A  91
LEU A  79
PHE A  78
ILE A 141
 None
 0.90A 4xv2A-2c4nA:
undetectable		 4xv2A-2c4nA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cfm THERMOSTABLE DNA
LIGASE

(Pyrococcus
furiosus) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		4 GLY A 169
LEU A  30
PHE A  29
ILE A  45
 None
 0.81A 4xv2A-2cfmA:
undetectable		 4xv2A-2cfmA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2csq RIM BINDING PROTEIN
2

(Homo sapiens) 		PF07653
(SH3_2) 		4 GLY A   4
LEU A  42
PHE A  44
ILE A  50
 None
 0.98A 4xv2A-2csqA:
undetectable		 4xv2A-2csqA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ekm HYPOTHETICAL PROTEIN
ST1511

(Sulfurisphaera
tokodaii) 		PF04008
(Adenosine_kin) 		4 GLY A  21
LEU A  36
PHE A  45
ILE A  47
 None
 0.99A 4xv2A-2ekmA:
undetectable		 4xv2A-2ekmA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus scrofa) 		PF05187
(ETF_QO)
PF13450
(NAD_binding_8) 		4 GLY A 214
LEU A 415
PHE A 338
ILE A 341
 FAD  A 611 (-3.4A)
None
None
None
 0.89A 4xv2A-2gmhA:
undetectable		 4xv2A-2gmhA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2klb PUTATIVE DIFLAVIN
FLAVOPROTEIN A 3

(Nostoc sp. PCC
7120) 		no annotation 4 GLY A  91
LEU A  36
PHE A   5
ILE A  57
 None
 0.90A 4xv2A-2klbA:
undetectable		 4xv2A-2klbA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oox HYPOTHETICAL PROTEIN
C1556.08C IN
CHROMOSOME I

(Schizosaccharomyces
pombe) 		no annotation 4 GLY G 302
LEU G 276
PHE G 280
ILE G 309
 None
 0.98A 4xv2A-2ooxG:
undetectable		 4xv2A-2ooxG:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qe6 UNCHARACTERIZED
PROTEIN TFU_2867

(Thermobifida
fusca) 		PF04672
(Methyltransf_19) 		4 GLY A 164
LEU A  71
PHE A  70
ILE A 268
 SAM  A 400 (-3.5A)
None
None
None
 0.80A 4xv2A-2qe6A:
undetectable		 4xv2A-2qe6A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zu8 MANNOSYL-3-PHOSPHOGL
YCERATE SYNTHASE

(Pyrococcus
horikoshii) 		PF09488
(Osmo_MPGsynth) 		4 GLY A 130
LEU A 150
PHE A 264
ILE A 370
 None
 0.84A 4xv2A-2zu8A:
undetectable		 4xv2A-2zu8A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a9x SELENOCYSTEINE LYASE

(Rattus
norvegicus) 		PF00266
(Aminotran_5) 		4 GLY A  87
LEU A 267
PHE A 280
ILE A  82
 PLP  A 501 (-3.7A)
None
None
None
 0.94A 4xv2A-3a9xA:
undetectable		 4xv2A-3a9xA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al0 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Thermotoga
maritima) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		4 GLY B 194
LEU B 177
PHE B 173
ILE B  11
 None
 0.96A 4xv2A-3al0B:
1.3		 4xv2A-3al0B:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE

(Plectranthus
scutellarioides) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 GLY A 222
LEU A 116
PHE A 142
ILE A 198
 None
 0.92A 4xv2A-3bazA:
undetectable		 4xv2A-3bazA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bre PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR

(Pseudomonas
aeruginosa) 		PF00072
(Response_reg)
PF00990
(GGDEF) 		4 GLY A 299
LEU A 189
PHE A 312
ILE A 316
 None
 0.86A 4xv2A-3breA:
undetectable		 4xv2A-3breA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3daq DIHYDRODIPICOLINATE
SYNTHASE

(Staphylococcus
aureus) 		PF00701
(DHDPS) 		4 GLY A  98
LEU A   4
PHE A   5
ILE A  76
 None
 0.79A 4xv2A-3daqA:
undetectable		 4xv2A-3daqA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dqz ALPHA-HYDROXYNITRILE
LYASE-LIKE PROTEIN

(Arabidopsis
thaliana) 		PF12697
(Abhydrolase_6) 		4 GLY A  83
LEU A  66
PHE A  94
ILE A  63
 None
 0.98A 4xv2A-3dqzA:
undetectable		 4xv2A-3dqzA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e4e CYTOCHROME P450 2E1

(Homo sapiens) 		PF00067
(p450) 		4 GLY A 137
LEU A 449
PHE A 448
ILE A 341
 None
 0.91A 4xv2A-3e4eA:
undetectable		 4xv2A-3e4eA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gyr PHENOXAZINONE
SYNTHASE

(Streptomyces
antibioticus) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 GLY A 483
LEU A 519
PHE A 546
ILE A 479
 None
 0.81A 4xv2A-3gyrA:
undetectable		 4xv2A-3gyrA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gzd SELENOCYSTEINE LYASE

(Homo sapiens) 		PF00266
(Aminotran_5) 		4 GLY C  98
LEU C 279
PHE C 292
ILE C  94
 PLR  C 500 ( 4.5A)
None
None
None
 0.95A 4xv2A-3gzdC:
undetectable		 4xv2A-3gzdC:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gzd SELENOCYSTEINE LYASE

(Homo sapiens) 		PF00266
(Aminotran_5) 		4 GLY C  99
LEU C 279
PHE C 292
ILE C  94
 PLR  C 500 (-3.6A)
None
None
None
 0.92A 4xv2A-3gzdC:
undetectable		 4xv2A-3gzdC:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hc7 GENE 12 PROTEIN

(Mycobacterium
virus D29) 		PF01083
(Cutinase) 		4 GLY A  21
LEU A 251
PHE A 250
ILE A 114
 None
 0.84A 4xv2A-3hc7A:
undetectable		 4xv2A-3hc7A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hi0 PUTATIVE
EXOPOLYPHOSPHATASE

(Agrobacterium
fabrum) 		PF02541
(Ppx-GppA) 		4 GLY A 144
LEU A 247
PHE A 246
ILE A 218
 None
 0.86A 4xv2A-3hi0A:
undetectable		 4xv2A-3hi0A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4t DIPHTHINE SYNTHASE

(Entamoeba
histolytica) 		PF00590
(TP_methylase) 		4 GLY A  83
LEU A 160
PHE A 127
ILE A 117
 None
 0.78A 4xv2A-3i4tA:
undetectable		 4xv2A-3i4tA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5b WSPR RESPONSE
REGULATOR

(Pseudomonas
aeruginosa) 		PF00990
(GGDEF) 		4 GLY A 299
LEU A 189
PHE A 312
ILE A 316
 None
 0.95A 4xv2A-3i5bA:
1.7		 4xv2A-3i5bA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6s SUBTILISIN-LIKE
PROTEASE

(Solanum
lycopersicum) 		PF00082
(Peptidase_S8) 		4 GLY A 173
LEU A 185
PHE A 154
ILE A 147
 None
 0.96A 4xv2A-3i6sA:
undetectable		 4xv2A-3i6sA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ic9 DIHYDROLIPOAMIDE
DEHYDROGENASE

(Colwellia
psychrerythraea) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 GLY A  37
LEU A 276
PHE A 118
ILE A  11
 FAD  A 490 ( 4.2A)
None
None
FAD  A 490 (-4.8A)
 0.81A 4xv2A-3ic9A:
undetectable		 4xv2A-3ic9A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihv SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 GLY A  80
LEU A  66
PHE A  67
ILE A  87
 None
 0.98A 4xv2A-3ihvA:
1.4		 4xv2A-3ihvA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ja6 CHEMOTAXIS PROTEIN
CHEW

(Escherichia
coli) 		PF01584
(CheW) 		4 GLY A 124
LEU A  65
PHE A  93
ILE A 141
 None
 0.99A 4xv2A-3ja6A:
undetectable		 4xv2A-3ja6A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k28 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
2

(Bacillus
anthracis) 		PF00202
(Aminotran_3) 		4 GLY A 336
LEU A 427
PHE A 379
ILE A 346
 None
 0.94A 4xv2A-3k28A:
undetectable		 4xv2A-3k28A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n3b RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
SUBUNIT BETA

(Escherichia
coli) 		no annotation 4 GLY B 144
LEU B 225
PHE B 156
ILE B 152
 None
 0.98A 4xv2A-3n3bB:
undetectable		 4xv2A-3n3bB:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nbi RECQ-MEDIATED GENOME
INSTABILITY PROTEIN
1

(Homo sapiens) 		PF08585
(RMI1_N) 		4 GLY A 142
LEU A  81
PHE A 175
ILE A  73
 None
 0.95A 4xv2A-3nbiA:
undetectable		 4xv2A-3nbiA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oaj PUTATIVE
RING-CLEAVING
DIOXYGENASE MHQO

(Bacillus
subtilis) 		PF00903
(Glyoxalase) 		4 GLY A 196
LEU A  32
PHE A  51
ILE A  62
 None
 0.92A 4xv2A-3oajA:
undetectable		 4xv2A-3oajA:
20.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3omv RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 GLY A 358
LEU A 397
PHE A 408
ILE A 419
 None
None
None
SM5  A   1 ( 4.3A)
 0.71A 4xv2A-3omvA:
35.1		 4xv2A-3omvA:
72.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pic CIP2

(Trichoderma
reesei) 		no annotation 4 GLY A 283
LEU A 202
PHE A 414
ILE A 369
 None
 0.98A 4xv2A-3picA:
undetectable		 4xv2A-3picA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rr5 DNA LIGASE

(Thermococcus
sp. 1519) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		4 GLY A 180
LEU A  41
PHE A  40
ILE A  56
 None
 0.93A 4xv2A-3rr5A:
undetectable		 4xv2A-3rr5A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sfw DIHYDROPYRIMIDINASE

(Brevibacillus
agri) 		PF01979
(Amidohydro_1) 		4 GLY A  84
LEU A  61
PHE A  74
ILE A  89
 None
 0.86A 4xv2A-3sfwA:
undetectable		 4xv2A-3sfwA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sfw DIHYDROPYRIMIDINASE

(Brevibacillus
agri) 		PF01979
(Amidohydro_1) 		4 GLY A  85
LEU A  61
PHE A  74
ILE A  89
 None
 0.95A 4xv2A-3sfwA:
undetectable		 4xv2A-3sfwA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v98 ARACHIDONATE
5-LIPOXYGENASE

(Homo sapiens) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 GLY A  13
LEU A 111
PHE A  97
ILE A  85
 None
 0.88A 4xv2A-3v98A:
undetectable		 4xv2A-3v98A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Burkholderia
pseudomallei) 		PF00496
(SBP_bac_5) 		4 GLY A 346
LEU A 527
PHE A 296
ILE A 292
 None
 0.90A 4xv2A-3zs6A:
undetectable		 4xv2A-3zs6A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dyo ASPARTYL
AMINOPEPTIDASE

(Homo sapiens) 		PF02127
(Peptidase_M18) 		4 GLY A  92
LEU A  42
PHE A  65
ILE A  73
 None
 0.82A 4xv2A-4dyoA:
undetectable		 4xv2A-4dyoA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e51 HISTIDINE--TRNA
LIGASE

(Burkholderia
thailandensis) 		PF03129
(HGTP_anticodon)
PF13393
(tRNA-synt_His) 		4 GLY A 310
LEU A 250
PHE A 257
ILE A 171
 HIS  A 501 (-3.3A)
None
None
None
 0.98A 4xv2A-4e51A:
undetectable		 4xv2A-4e51A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eo3 BACTERIOFERRITIN
COMIGRATORY
PROTEIN/NADH
DEHYDROGENASE

(Thermotoga
maritima) 		PF00578
(AhpC-TSA)
PF00881
(Nitroreductase) 		4 GLY A 112
LEU A 134
PHE A  52
ILE A  28
 None
 0.95A 4xv2A-4eo3A:
1.9		 4xv2A-4eo3A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eq5 DNA LIGASE

(Thermococcus
sibiricus) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		4 GLY A 181
LEU A  41
PHE A  40
ILE A  57
 None
 0.93A 4xv2A-4eq5A:
undetectable		 4xv2A-4eq5A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fsp PROBABLE PORIN

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		4 GLY A 185
LEU A 149
PHE A 129
ILE A 117
 C8E  A 406 ( 4.0A)
None
None
None
 0.98A 4xv2A-4fspA:
undetectable		 4xv2A-4fspA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h5i GUANINE
NUCLEOTIDE-EXCHANGE
FACTOR SEC12

(Saccharomyces
cerevisiae) 		no annotation 4 GLY A  30
LEU A  45
PHE A  58
ILE A 333
 None
 0.96A 4xv2A-4h5iA:
undetectable		 4xv2A-4h5iA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ieg RNA-DEPENDENT RNA
POLYMERASE P2

(Pseudomonas
phage phi12) 		no annotation 4 GLY A 510
LEU A 340
PHE A 339
ILE A 465
 None
 0.93A 4xv2A-4iegA:
1.5		 4xv2A-4iegA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kqn D-HYDANTOINASE

(Bacillus sp.
AR9) 		PF01979
(Amidohydro_1) 		4 GLY A  84
LEU A  61
PHE A  74
ILE A  89
 GLY  A  84 ( 0.0A)
LEU  A  61 ( 0.6A)
PHE  A  74 ( 1.3A)
ILE  A  89 ( 0.6A)
 0.83A 4xv2A-4kqnA:
undetectable		 4xv2A-4kqnA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kqn D-HYDANTOINASE

(Bacillus sp.
AR9) 		PF01979
(Amidohydro_1) 		4 GLY A  85
LEU A  61
PHE A  74
ILE A  89
 GLY  A  85 ( 0.0A)
LEU  A  61 ( 0.6A)
PHE  A  74 ( 1.3A)
ILE  A  89 ( 0.6A)
 0.92A 4xv2A-4kqnA:
undetectable		 4xv2A-4kqnA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mmg MRNA INTERFERASE
YAFQ

(Escherichia
coli) 		PF15738
(YafQ_toxin) 		4 GLY A  10
LEU A  90
PHE A  91
ILE A  71
 None
 0.95A 4xv2A-4mmgA:
undetectable		 4xv2A-4mmgA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0q LEU/ILE/VAL-BINDING
PROTEIN HOMOLOG 3

(Brucella
melitensis) 		PF13458
(Peripla_BP_6) 		4 GLY A 215
LEU A 231
PHE A 221
ILE A 166
 None
 0.94A 4xv2A-4n0qA:
undetectable		 4xv2A-4n0qA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C

(Butyrivibrio
proteoclasticus) 		PF00150
(Cellulase) 		4 GLY A 103
LEU A 137
PHE A 184
ILE A 171
 None
 0.94A 4xv2A-4nf7A:
undetectable		 4xv2A-4nf7A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o8u UNCHARACTERIZED
PROTEIN PF2046

(Pyrococcus
furiosus) 		PF13680
(DUF4152) 		4 GLY A 157
LEU A  21
PHE A  25
ILE A 230
 None
 0.95A 4xv2A-4o8uA:
undetectable		 4xv2A-4o8uA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0f SERINE PROTEASE
INHIBITOR 4, ISOFORM
B

(Drosophila
melanogaster) 		PF00079
(Serpin) 		4 GLY A 374
LEU A 281
PHE A 285
ILE A  40
 None
 0.91A 4xv2A-4p0fA:
undetectable		 4xv2A-4p0fA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rcn LONG-CHAIN ACYL-COA
CARBOXYLASE

(Mycobacterium
avium) 		PF00289
(Biotin_carb_N)
PF01039
(Carboxyl_trans)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 GLY A 981
LEU A 921
PHE A 920
ILE A 898
 None
 0.82A 4xv2A-4rcnA:
undetectable		 4xv2A-4rcnA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rul DNA TOPOISOMERASE 1

(Escherichia
coli) 		PF01131
(Topoisom_bac)
PF01396
(zf-C4_Topoisom)
PF01751
(Toprim)
PF08272
(Topo_Zn_Ribbon) 		4 GLY A 315
LEU A 289
PHE A 284
ILE A 394
 None
 0.99A 4xv2A-4rulA:
undetectable		 4xv2A-4rulA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uzg SURFACE PROTEIN SPB1

(Streptococcus
agalactiae) 		no annotation 4 GLY A 352
LEU A 421
PHE A 372
ILE A 356
 None
 0.90A 4xv2A-4uzgA:
undetectable		 4xv2A-4uzgA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uzr PUTATIVE
UNCHARACTERIZED
PROTEIN PH1500

(Pyrococcus
horikoshii) 		PF02933
(CDC48_2) 		4 GLY A  33
LEU A  11
PHE A  53
ILE A  27
 None
 0.89A 4xv2A-4uzrA:
undetectable		 4xv2A-4uzrA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wrn MALTOSE-BINDING
PERIPLASMIC
PROTEIN,UROMODULIN

(Escherichia
coli;
Homo sapiens) 		PF00100
(Zona_pellucida)
PF13416
(SBP_bac_8) 		4 GLY A 588
LEU A 579
PHE A 653
ILE A 704
 None
 0.81A 4xv2A-4wrnA:
undetectable		 4xv2A-4wrnA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a0t RIBONUCLEASE J

(Streptomyces
coelicolor) 		PF00753
(Lactamase_B)
PF07521
(RMMBL) 		4 GLY A 368
LEU A 225
PHE A 229
ILE A 337
 None
 0.97A 4xv2A-5a0tA:
undetectable		 4xv2A-5a0tA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8r METHYL-COENZYME M
REDUCTASE II SUBUNIT
ALPHA

(Methanothermobacter
marburgensis) 		PF02249
(MCR_alpha)
PF02745
(MCR_alpha_N) 		4 GLY A 224
LEU A 316
PHE A 289
ILE A 104
 None
 0.99A 4xv2A-5a8rA:
undetectable		 4xv2A-5a8rA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d5t UNCHARACTERIZED
PROTEIN MJ0489

(Methanocaldococcus
jannaschii) 		PF06690
(DUF1188) 		4 GLY A  59
LEU A  42
PHE A  41
ILE A 137
 None
 0.97A 4xv2A-5d5tA:
undetectable		 4xv2A-5d5tA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e0c CELLULASE

(Bacillus sp.
BG-CS10) 		PF00150
(Cellulase)
PF03442
(CBM_X2) 		4 GLY A 237
LEU A 274
PHE A 277
ILE A 284
 None
 0.96A 4xv2A-5e0cA:
undetectable		 4xv2A-5e0cA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fif CARBOXYLASE

(Deinococcus
radiodurans) 		PF01039
(Carboxyl_trans) 		4 GLY A 426
LEU A 366
PHE A 365
ILE A 343
 None
 0.81A 4xv2A-5fifA:
undetectable		 4xv2A-5fifA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lon KLLA0E01827P

(Kluyveromyces
lactis) 		PF06058
(DCP1) 		4 GLY B  52
LEU B  28
PHE B  15
ILE B  18
 None
 0.71A 4xv2A-5lonB:
undetectable		 4xv2A-5lonB:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mkg DIGUANYLATE
PHOSPHODIESTERASE

(Pseudomonas
aeruginosa) 		PF00563
(EAL) 		4 GLY B  30
LEU B 200
PHE B 186
ILE B 182
 None
 0.83A 4xv2A-5mkgB:
undetectable		 4xv2A-5mkgB:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mvo FOXE

(Rhodobacter sp.
SW2) 		no annotation 4 GLY A  82
LEU A 248
PHE A 249
ILE A 107
 None
 0.78A 4xv2A-5mvoA:
undetectable		 4xv2A-5mvoA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nmp ISATIN HYDROLASE

(Ralstonia
solanacearum) 		no annotation 4 GLY A 191
LEU A 130
PHE A 129
ILE A 111
 None
 0.99A 4xv2A-5nmpA:
undetectable		 4xv2A-5nmpA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj1 DNA TOPOISOMERASE 1

(Mycobacterium
tuberculosis) 		no annotation 4 GLY A 338
LEU A 312
PHE A 307
ILE A 423
 None
 0.97A 4xv2A-5uj1A:
undetectable		 4xv2A-5uj1A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x1y MERCURIC REDUCTASE

(Lysinibacillus
sphaericus) 		no annotation 4 GLY B 116
LEU B 354
PHE B 197
ILE B  90
 FAD  B 601 (-4.0A)
FAD  B 601 (-4.6A)
None
FAD  B 601 (-4.9A)
 0.83A 4xv2A-5x1yB:
undetectable		 4xv2A-5x1yB:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xb0 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Pseudomonas
syringae group
genomosp. 3) 		PF00254
(FKBP_C) 		4 GLY A  92
LEU A 151
PHE A 157
ILE A 207
 None
 0.89A 4xv2A-5xb0A:
undetectable		 4xv2A-5xb0A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ylv POTASSIUM-TRANSPORTI
NG ATPASE SUBUNIT
BETA

(Sus scrofa) 		no annotation 4 GLY B 171
LEU B 117
PHE B 116
ILE B 180
 None
 0.92A 4xv2A-5ylvB:
undetectable		 4xv2A-5ylvB:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aun PLA2G6, IPLA2BETA

(Cricetulus
griseus) 		no annotation 4 GLY A 532
LEU A 510
PHE A 509
ILE A 469
 None
 0.96A 4xv2A-6aunA:
undetectable		 4xv2A-6aunA:
14.63