SIMILAR PATTERNS OF AMINO ACIDS FOR 4XUE_A_SAMA303_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a3y ODORANT BINDING
PROTEIN

(Sus scrofa) 		PF00061
(Lipocalin) 		5 ASN A 148
TYR A  20
ILE A 100
ILE A  99
SER A 101
 None
 1.23A 4xueA-1a3yA:
undetectable		 4xueA-1a3yA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1awb MYO-INOSITOL
MONOPHOSPHATASE

(Homo sapiens) 		PF00459
(Inositol_P) 		5 MET A 200
ASN A 199
VAL A 198
ILE A  89
ILE A  88
 None
 1.38A 4xueA-1awbA:
undetectable		 4xueA-1awbA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dtd CARBOXYPEPTIDASE A2

(Homo sapiens) 		PF00246
(Peptidase_M14) 		5 ASN A 393
VAL A 392
ILE A 423
ASN A 467
SER A 610
 None
 1.39A 4xueA-1dtdA:
undetectable		 4xueA-1dtdA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dtd CARBOXYPEPTIDASE A2

(Homo sapiens) 		PF00246
(Peptidase_M14) 		5 ASN A 404
VAL A 392
ILE A 423
ASN A 467
SER A 610
 None
 1.31A 4xueA-1dtdA:
undetectable		 4xueA-1dtdA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fp3 N-ACYL-D-GLUCOSAMINE
2-EPIMERASE

(Sus scrofa) 		PF07221
(GlcNAc_2-epim) 		5 ASN A 132
ILE A 121
CYH A 187
SER A 120
GLN A 118
 None
 1.23A 4xueA-1fp3A:
undetectable		 4xueA-1fp3A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j05 ANTI-CEA MAB T84.66,
HEAVY CHAIN
ANTI-CEA MAB T84.66,
LIGHT CHAIN

(Mus musculus;
Mus musculus) 		no annotation
no annotation 		5 VAL H  99
TYR H 101
ILE L  58
ILE L  48
ASN L  53
 None
 1.38A 4xueA-1j05H:
undetectable		 4xueA-1j05H:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k8f ADENYLYL
CYCLASE-ASSOCIATED
PROTEIN

(Homo sapiens) 		PF08603
(CAP_C) 		5 ASN A 333
VAL A 321
TYR A 354
ILE A 370
SER A 369
 None
 1.43A 4xueA-1k8fA:
undetectable		 4xueA-1k8fA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lf9 GLUCOAMYLASE

(Thermoanaerobacterium
thermosaccharolyticum) 		PF00723
(Glyco_hydro_15)
PF09137
(Glucodextran_N) 		5 VAL A 340
TYR A 337
ILE A 304
ILE A 634
SER A 301
 None
ACR  A 700 (-4.3A)
None
None
None
 1.27A 4xueA-1lf9A:
undetectable		 4xueA-1lf9A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1on9 METHYLMALONYL-COA
CARBOXYLTRANSFERASE
12S SUBUNIT

(Propionibacterium
freudenreichii) 		PF01039
(Carboxyl_trans) 		5 VAL A 318
TYR A 313
ILE A 194
ILE A 193
ASN A 234
 None
 1.15A 4xueA-1on9A:
undetectable		 4xueA-1on9A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wmm HYPOTHETICAL UPF0310
PROTEIN PH1033

(Pyrococcus
horikoshii) 		PF01878
(EVE) 		5 ASN A  20
VAL A  21
TYR A  64
ILE A   5
ILE A  60
 None
 1.41A 4xueA-1wmmA:
undetectable		 4xueA-1wmmA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xf1 C5A PEPTIDASE

(Streptococcus
pyogenes) 		PF00082
(Peptidase_S8)
PF02225
(PA)
PF06280
(fn3_5)
PF13585
(CHU_C) 		5 ASN A 871
TYR A 870
ASN A 841
SER A 717
GLN A 919
 None
None
CIT  A1101 (-3.8A)
None
None
 1.45A 4xueA-1xf1A:
undetectable		 4xueA-1xf1A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d5r CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 7

(Homo sapiens) 		PF04857
(CAF1) 		5 ASN A  83
ILE A  12
ILE A 221
SER A 229
GLN A 224
 None
 1.41A 4xueA-2d5rA:
undetectable		 4xueA-2d5rA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nty RAC-LIKE GTP-BINDING
PROTEIN ARAC5

(Arabidopsis
thaliana) 		PF00071
(Ras) 		5 ASN C 165
VAL C 166
ILE C  88
ILE C 138
SER C  89
 None
 0.97A 4xueA-2ntyC:
undetectable		 4xueA-2ntyC:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qhk METHYL-ACCEPTING
CHEMOTAXIS PROTEIN

(Vibrio
parahaemolyticus) 		PF17200
(sCache_2) 		5 VAL A  33
ILE A 106
ASN A  76
SER A  72
GLN A  73
 None
 1.42A 4xueA-2qhkA:
undetectable		 4xueA-2qhkA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vsk HEMAGGLUTININ-NEURAM
INIDASE

(Hendra
henipavirus) 		PF00423
(HN) 		5 ASN A 306
ILE A 438
SER A 411
GLN A 455
TRP A 504
 None
 1.39A 4xueA-2vskA:
undetectable		 4xueA-2vskA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vsm HEMAGGLUTININ-NEURAM
INIDASE

(Nipah
henipavirus) 		PF00423
(HN) 		5 ASN A 306
ILE A 438
SER A 411
GLN A 455
TRP A 504
 None
 1.49A 4xueA-2vsmA:
undetectable		 4xueA-2vsmA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yik ENDOGLUCANASE

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9) 		5 ASN A 502
ILE A 402
ILE A 315
SER A 323
HIS A 316
 None
 1.38A 4xueA-2yikA:
undetectable		 4xueA-2yikA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yoc PULLULANASE

(Klebsiella
oxytoca) 		PF02922
(CBM_48)
PF03714
(PUD)
PF11852
(DUF3372) 		5 VAL A  86
TYR A  66
ILE A  44
ILE A 111
ASN A 112
 None
 0.93A 4xueA-2yocA:
1.4		 4xueA-2yocA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zk7 GLUCOSE
1-DEHYDROGENASE
RELATED PROTEIN

(Thermoplasma
acidophilum) 		PF13561
(adh_short_C2) 		5 ASN A  56
VAL A  60
ILE A 101
ILE A 100
SER A 148
 None
 1.47A 4xueA-2zk7A:
8.0		 4xueA-2zk7A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aag GENERAL
GLYCOSYLATION
PATHWAY PROTEIN

(Campylobacter
jejuni) 		PF02516
(STT3) 		5 ASN A 691
TYR A 645
ASN A 638
SER A 664
GLN A 670
 None
MLY  A 646 ( 4.1A)
None
None
None
 1.27A 4xueA-3aagA:
1.5		 4xueA-3aagA:
18.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3bwm CATECHOL
O-METHYLTRANSFERASE

(Homo sapiens) 		PF01596
(Methyltransf_3) 		12 MET A  40
ASN A  41
VAL A  42
TYR A  68
ILE A  89
ILE A  91
ASN A  92
CYH A  95
SER A 119
GLN A 120
HIS A 142
TRP A 143
 SAM  A 301 (-3.7A)
SAM  A 301 (-4.7A)
SAM  A 301 ( 3.7A)
SAM  A 301 (-4.7A)
SAM  A 301 ( 4.9A)
SAM  A 301 (-3.9A)
None
SAM  A 301 ( 4.2A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.6A)
SAM  A 301 ( 4.9A)
SAM  A 301 ( 3.4A)
 0.20A 4xueA-3bwmA:
41.1		 4xueA-3bwmA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dtc MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 9

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		5 MET A 220
VAL A 168
ILE A 276
ILE A 274
ASN A 273
 VIN  A6331 (-3.7A)
None
None
None
VIN  A6331 ( 4.8A)
 1.47A 4xueA-3dtcA:
undetectable		 4xueA-3dtcA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g0t PUTATIVE
AMINOTRANSFERASE

(Porphyromonas
gingivalis) 		PF00155
(Aminotran_1_2) 		5 VAL A  98
ILE A 218
ILE A 216
ASN A 250
SER A 120
 None
None
None
EDO  A 441 (-3.4A)
None
 1.19A 4xueA-3g0tA:
3.3		 4xueA-3g0tA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hoi FMN-DEPENDENT
NITROREDUCTASE
BF3017

(Bacteroides
fragilis) 		PF00881
(Nitroreductase) 		5 VAL A  94
ASN A  68
SER A 168
GLN A 165
HIS A 205
 None
 1.49A 4xueA-3hoiA:
undetectable		 4xueA-3hoiA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3is5 CALCIUM-DEPENDENT
PROTEIN KINASE

(Toxoplasma
gondii) 		PF00069
(Pkinase) 		5 VAL A 324
ILE A 280
ILE A 193
ASN A 192
HIS A 258
 None
ANP  A   1 (-4.2A)
None
None
None
 1.30A 4xueA-3is5A:
undetectable		 4xueA-3is5A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kn5 RIBOSOMAL PROTEIN S6
KINASE ALPHA-5

(Homo sapiens) 		PF00069
(Pkinase) 		5 VAL A 610
ILE A 564
ILE A 481
ASN A 480
HIS A 542
 None
ANP  A 400 (-3.9A)
None
None
None
 1.24A 4xueA-3kn5A:
undetectable		 4xueA-3kn5A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ma6 CALMODULIN-DOMAIN
PROTEIN KINASE 1

(Toxoplasma
gondii) 		PF00069
(Pkinase) 		5 VAL A 221
ILE A 177
ILE A  94
ASN A  93
HIS A 155
 None
DXR  A 299 ( 3.6A)
None
None
None
 1.30A 4xueA-3ma6A:
undetectable		 4xueA-3ma6A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbr GLUTAMINE
CYCLOTRANSFERASE

(Xanthomonas
campestris) 		PF05096
(Glu_cyclase_2) 		5 VAL X 179
TYR X 139
ILE X  91
ILE X  99
TRP X  94
 None
 1.08A 4xueA-3mbrX:
undetectable		 4xueA-3mbrX:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tl2 MALATE DEHYDROGENASE

(Bacillus
anthracis) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		5 MET A 308
VAL A 310
TYR A 132
ILE A 256
SER A 149
 None
 1.43A 4xueA-3tl2A:
4.9		 4xueA-3tl2A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v0a NTNH

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07953
(Toxin_R_bind_N)
PF08470
(NTNH_C) 		5 ASN B 586
ILE B 573
ILE B 740
ASN B 743
SER B 570
 None
 1.16A 4xueA-3v0aB:
undetectable		 4xueA-3v0aB:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wrf NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE

(Bifidobacterium
longum) 		PF07944
(Glyco_hydro_127) 		5 VAL A 405
ILE A 374
ILE A 422
ASN A 421
CYH A 340
 None
 1.25A 4xueA-3wrfA:
undetectable		 4xueA-3wrfA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wrf NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE

(Bifidobacterium
longum) 		PF07944
(Glyco_hydro_127) 		5 VAL A 405
TYR A 386
ILE A 422
ASN A 421
CYH A 340
 None
 1.28A 4xueA-3wrfA:
undetectable		 4xueA-3wrfA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dz4 AGMATINASE

(Burkholderia
thailandensis) 		PF00491
(Arginase) 		5 VAL A 271
ILE A 198
ILE A 208
ASN A 209
HIS A 157
 None
 1.06A 4xueA-4dz4A:
undetectable		 4xueA-4dz4A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oav PROTEIN (RNASE L)

(Homo sapiens) 		PF00069
(Pkinase)
PF06479
(Ribonuc_2-5A)
PF12796
(Ank_2)
PF13857
(Ank_5) 		5 VAL B 389
ILE B 493
ILE B 491
ASN B 490
HIS B 500
 None
None
None
MG  B 802 ( 2.5A)
None
 1.09A 4xueA-4oavB:
undetectable		 4xueA-4oavB:
16.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4p58 CATECHOL
O-METHYLTRANSFERASE

(Mus musculus) 		PF01596
(Methyltransf_3) 		5 ILE A 134
ASN A 135
SER A 162
GLN A 163
HIS A 185
 2F6  A 301 (-3.7A)
None
2F6  A 301 (-3.2A)
2F6  A 301 (-3.8A)
None
 0.45A 4xueA-4p58A:
33.5		 4xueA-4p58A:
81.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rp8 ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA

(Escherichia
coli) 		PF03611
(EIIC-GAT) 		5 MET A 176
ASN A 175
TYR A 442
ILE A 164
ILE A 435
 None
 1.40A 4xueA-4rp8A:
undetectable		 4xueA-4rp8A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4web MOUSE FAB HEAVY
CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		5 TYR H  95
ILE H  70
ILE H  48
ASN H  38
HIS H  35
 None
 1.46A 4xueA-4webH:
undetectable		 4xueA-4webH:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z7y DIPHOSPHOMEVALONATE
DECARBOXYLASE

(Sulfolobus
solfataricus) 		PF00288
(GHMP_kinases_N) 		5 MET A 239
ASN A 243
TYR A 278
ILE A 182
ILE A 181
 None
 1.34A 4xueA-4z7yA:
undetectable		 4xueA-4z7yA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zgv FERREDOXIN RECEPTOR

(Pectobacterium
atrosepticum) 		PF07715
(Plug) 		5 MET A 660
TYR A 574
ILE A 139
ASN A 140
SER A 450
 None
 1.09A 4xueA-4zgvA:
undetectable		 4xueA-4zgvA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8v POLYHEDRIN

(Cypovirus 5) 		no annotation 5 ASN A 229
VAL A  42
ILE A 113
SER A 174
GLN A 162
 None
 1.41A 4xueA-5a8vA:
undetectable		 4xueA-5a8vA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR

(Homo sapiens) 		no annotation 5 ASN B 512
VAL B 513
TYR B 510
ILE B 318
ASN B 524
 None
 1.22A 4xueA-5fbhB:
4.7		 4xueA-5fbhB:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5juh ANTIFREEZE PROTEIN

(Marinomonas
primoryensis) 		PF08548
(Peptidase_M10_C) 		5 ASN A 147
TYR A 146
ILE A 142
ILE A 153
SER A 141
 None
 1.44A 4xueA-5juhA:
undetectable		 4xueA-5juhA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kf2 PREDICTED
ACETYLTRANSFERASE

(Clostridium
acetobutylicum) 		PF00583
(Acetyltransf_1) 		5 ASN A  49
ILE A  81
ILE A  82
ASN A  19
SER A  80
 None
ACO  A 402 (-4.5A)
ACO  A 402 (-4.4A)
EDO  A 403 (-4.7A)
None
 1.45A 4xueA-5kf2A:
undetectable		 4xueA-5kf2A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE DELTA
SUBUNIT
ACETOPHENONE
CARBOXYLASE GAMMA
SUBUNIT

(Aromatoleum
aromaticum;
Aromatoleum
aromaticum) 		PF02538
(Hydantoinase_B)
PF01968
(Hydantoinase_A)
PF05378
(Hydant_A_N) 		5 VAL B 178
ILE B 106
SER A 463
GLN A 483
HIS B 100
 None
 1.38A 4xueA-5l9wB:
3.0		 4xueA-5l9wB:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o0y SERINE/THREONINE-PRO
TEIN KINASE
TOUSLED-LIKE 2

(Homo sapiens) 		no annotation 5 ASN A 576
ILE A 589
ASN A 660
SER A 617
HIS A 590
 None
 1.14A 4xueA-5o0yA:
undetectable		 4xueA-5o0yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE

(Erwinia
amylovora) 		no annotation 5 VAL A 146
TYR A 154
ILE A  97
GLN A  99
HIS A 150
 None
 1.41A 4xueA-5o3zA:
8.1		 4xueA-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odv COAT PROTEIN

(Watermelon
mosaic virus) 		PF00767
(Poty_coat) 		5 MET A 127
ASN A 128
VAL A 125
CYH A 134
TRP A 108
 None
 1.50A 4xueA-5odvA:
undetectable		 4xueA-5odvA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x18 CASEIN KINASE I
HOMOLOG 1

(Saccharomyces
cerevisiae) 		PF00069
(Pkinase) 		5 VAL A 170
ILE A 125
ILE A 210
ASN A 193
HIS A 208
 None
None
GOL  A 402 ( 4.0A)
None
None
 1.11A 4xueA-5x18A:
undetectable		 4xueA-5x18A:
25.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bb9 4-AMINO-4-DEOXYCHORI
SMATE LYASE

(Salmonella
enterica) 		no annotation 5 ASN A 198
VAL A 197
ILE A 242
ILE A 233
CYH A 205
 CL  A 305 ( 4.8A)
MES  A 301 (-4.1A)
None
None
None
 1.47A 4xueA-6bb9A:
undetectable		 4xueA-6bb9A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cwx RIBONUCLEASE P
PROTEIN SUBUNIT P20

(Homo sapiens) 		no annotation 5 ASN A 127
VAL A 105
ILE A  71
ILE A  82
ASN A  79
 None
None
None
None
CME  B  70 ( 4.9A)
 0.98A 4xueA-6cwxA:
undetectable		 4xueA-6cwxA:
undetectable