SIMILAR PATTERNS OF AMINO ACIDS FOR 4XQE_B_AG2B505

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ct9 ASPARAGINE
SYNTHETASE B

(Escherichia
coli) 		PF00733
(Asn_synthase)
PF13537
(GATase_7) 		4 ARG A 387
ASP A 384
VAL A 320
ASP A 319
 None
IUM  A1103 (-2.7A)
None
None
 1.03A 4xqeB-1ct9A:
2.3		 4xqeB-1ct9A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d5f E6AP HECT CATALYTIC
DOMAIN, E3 LIGASE

(Homo sapiens) 		PF00632
(HECT) 		4 ARG A 616
ARG A 626
VAL A 613
ASP A 627
 None
 1.37A 4xqeB-1d5fA:
undetectable		 4xqeB-1d5fA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN

(Propionibacterium
freudenreichii) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding) 		4 ARG A 596
ASP A 648
VAL A 628
ASP A 629
 None
 1.28A 4xqeB-1e1cA:
undetectable		 4xqeB-1e1cA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6y METHYL-COENZYME M
REDUCTASE SUBUNIT
GAMMA

(Methanosarcina
barkeri) 		PF02240
(MCR_gamma) 		4 ARG C3129
ARG C3044
ASP C3049
ASP C3081
 None
 1.19A 4xqeB-1e6yC:
undetectable		 4xqeB-1e6yC:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1euz GLUTAMATE
DEHYDROGENASE

(Thermococcus
profundus) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 ARG A  16
ARG A 331
ASP A 397
ASP A 328
 None
SO4  A 603 (-4.5A)
None
None
 1.25A 4xqeB-1euzA:
2.3		 4xqeB-1euzA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7y METHIONINE SYNTHASE

(Escherichia
coli) 		PF02310
(B12-binding)
PF02607
(B12-binding_2)
PF02965
(Met_synt_B12) 		4 ARG A 910
ASP A1202
VAL A1007
ASP A1010
 None
 1.25A 4xqeB-1k7yA:
3.8		 4xqeB-1k7yA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nne DNA MISMATCH REPAIR
PROTEIN MUTS

(Thermus
aquaticus) 		PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III) 		4 ARG A 285
ARG A 280
VAL A 529
ASP A 528
 None
 1.28A 4xqeB-1nneA:
undetectable		 4xqeB-1nneA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1olt OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE

(Escherichia
coli) 		PF04055
(Radical_SAM)
PF06969
(HemN_C) 		4 ARG A 371
ARG A  47
ASP A 334
ASP A 320
 None
 1.29A 4xqeB-1oltA:
undetectable		 4xqeB-1oltA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgj 6-PHOSPHOGLUCONATE
DEHYDROGENASE

(Trypanosoma
brucei) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 ARG A 298
ASP A 257
VAL A 423
ASP A 204
 None
 0.94A 4xqeB-1pgjA:
4.8		 4xqeB-1pgjA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qb4 PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Escherichia
coli) 		PF00311
(PEPcase) 		4 ARG A 581
ARG A 699
ASP A 543
ASP A 254
 None
None
MN  A 885 (-3.0A)
MN  A 885 ( 4.7A)
 1.38A 4xqeB-1qb4A:
undetectable		 4xqeB-1qb4A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qon ACETYLCHOLINESTERASE

(Drosophila
melanogaster) 		PF00135
(COesterase) 		4 ARG A 433
ASP A 437
VAL A 478
ASP A 366
 None
 1.36A 4xqeB-1qonA:
2.3		 4xqeB-1qonA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qvb BETA-GLYCOSIDASE

(Thermosphaera
aggregans) 		PF00232
(Glyco_hydro_1) 		4 ARG A 397
ASP A 391
VAL A 445
ASP A 428
 None
 1.37A 4xqeB-1qvbA:
undetectable		 4xqeB-1qvbA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rkx CDP-GLUCOSE-4,6-DEHY
DRATASE

(Yersinia
pseudotuberculosis) 		PF16363
(GDP_Man_Dehyd) 		4 ARG A 213
ARG A 206
ASP A 210
ASP A 201
 None
 1.32A 4xqeB-1rkxA:
8.8		 4xqeB-1rkxA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2v ARP2/3 COMPLEX 34KDA
SUBUNIT

(Bos taurus) 		PF04045
(P34-Arc) 		4 ARG D 118
ARG D 237
ASP D 238
VAL D 124
 None
 0.81A 4xqeB-1u2vD:
undetectable		 4xqeB-1u2vD:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3d CRYPTOCHROME 1
APOPROTEIN

(Arabidopsis
thaliana) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		4 ARG A  20
ARG A 118
ASP A 112
ASP A 119
 None
 1.05A 4xqeB-1u3dA:
undetectable		 4xqeB-1u3dA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3d CRYPTOCHROME 1
APOPROTEIN

(Arabidopsis
thaliana) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		4 ARG A 118
ARG A  20
ASP A 119
ASP A 112
 None
 0.93A 4xqeB-1u3dA:
undetectable		 4xqeB-1u3dA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE

(Thermotoga
maritima) 		PF01071
(GARS_A)
PF02843
(GARS_C)
PF02844
(GARS_N) 		4 ARG A 362
ASP A 280
VAL A 319
ASP A 318
 None
 1.19A 4xqeB-1vkzA:
5.7		 4xqeB-1vkzA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wqa PHOSPHO-SUGAR MUTASE

(Pyrococcus
horikoshii) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 ARG A  11
ARG A  51
ASP A 245
VAL A  10
 ARG  A  11 ( 0.6A)
ARG  A  51 ( 0.6A)
ASP  A 245 (-0.6A)
VAL  A  10 ( 0.6A)
 0.96A 4xqeB-1wqaA:
undetectable		 4xqeB-1wqaA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wuu GALACTOKINASE

(Homo sapiens) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C)
PF10509
(GalKase_gal_bdg) 		4 ARG A 279
ARG A 277
ASP A 317
VAL A 270
 None
 1.41A 4xqeB-1wuuA:
undetectable		 4xqeB-1wuuA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a6y EMP47P (FORM1)

(Saccharomyces
cerevisiae) 		PF03388
(Lectin_leg-like) 		4 ARG A  99
ASP A  94
VAL A 108
ASP A 100
 SO4  A 256 (-3.7A)
SO4  A 256 (-2.9A)
None
None
 1.40A 4xqeB-2a6yA:
undetectable		 4xqeB-2a6yA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bfw GLGA GLYCOGEN
SYNTHASE

(Pyrococcus
abyssi) 		PF00534
(Glycos_transf_1) 		4 ARG A 395
ARG A 402
ASP A 234
ASP A 330
 None
 1.28A 4xqeB-2bfwA:
7.6		 4xqeB-2bfwA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bfw GLGA GLYCOGEN
SYNTHASE

(Pyrococcus
abyssi) 		PF00534
(Glycos_transf_1) 		4 ARG A 402
ARG A 395
ASP A 330
ASP A 234
 None
 1.21A 4xqeB-2bfwA:
7.6		 4xqeB-2bfwA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hnh DNA POLYMERASE III
ALPHA SUBUNIT

(Escherichia
coli) 		PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		4 ARG A 303
ARG A 362
ASP A 378
VAL A 370
 None
 1.09A 4xqeB-2hnhA:
undetectable		 4xqeB-2hnhA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ps2 PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Aspergillus
oryzae) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ARG A 280
ASP A  88
VAL A 110
ASP A 109
 None
 1.37A 4xqeB-2ps2A:
undetectable		 4xqeB-2ps2A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qjj MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Novosphingobium
aromaticivorans) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ARG A  15
ARG A  84
VAL A 320
ASP A  33
 None
 1.38A 4xqeB-2qjjA:
undetectable		 4xqeB-2qjjA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qjw UNCHARACTERIZED
PROTEIN XCC1541

(Xanthomonas
campestris) 		no annotation 4 ARG A  61
ARG A  46
ASP A  42
VAL A  55
 None
 1.39A 4xqeB-2qjwA:
6.2		 4xqeB-2qjwA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vmx SERINE
HYDROXYMETHYLTRANSFE
RASE

(Geobacillus
stearothermophilus) 		PF00464
(SHMT) 		4 ARG A  75
ARG A  59
VAL A  67
ASP A  68
 None
 1.39A 4xqeB-2vmxA:
undetectable		 4xqeB-2vmxA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE

(Staphylococcus
aureus) 		PF00391
(PEP-utilizers)
PF02896
(PEP-utilizers_C)
PF05524
(PEP-utilisers_N) 		4 ARG A 360
ARG A 467
ASP A 457
ASP A 466
 None
 1.17A 4xqeB-2wqdA:
undetectable		 4xqeB-2wqdA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x66 PRNB

(Pseudomonas
fluorescens) 		PF08933
(DUF1864) 		4 ARG A 283
ARG A 353
ASP A 280
VAL A 354
 None
 1.00A 4xqeB-2x66A:
undetectable		 4xqeB-2x66A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xes PROTEIN PAT1 HOMOLOG
1

(Homo sapiens) 		PF09770
(PAT1) 		4 ARG A 578
ARG A 618
ASP A 611
ASP A 581
 None
 1.36A 4xqeB-2xesA:
undetectable		 4xqeB-2xesA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xij METHYLMALONYL-COA
MUTASE,
MITOCHONDRIAL

(Homo sapiens) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding) 		4 ARG A 613
ASP A 665
VAL A 645
ASP A 646
 None
 1.24A 4xqeB-2xijA:
undetectable		 4xqeB-2xijA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xy1 NEURAL CELL ADHESION
MOLECULE 2

(Homo sapiens) 		PF07679
(I-set) 		4 ARG A 353
ARG A 336
VAL A 370
ASP A 374
 None
 1.18A 4xqeB-2xy1A:
undetectable		 4xqeB-2xy1A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yw2 PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE

(Aquifex
aeolicus) 		PF01071
(GARS_A)
PF02843
(GARS_C)
PF02844
(GARS_N) 		4 ARG A 378
ASP A 290
VAL A 329
ASP A 328
 PO4  A 645 (-3.6A)
None
None
None
 1.24A 4xqeB-2yw2A:
7.0		 4xqeB-2yw2A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zii VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 74

(Saccharomyces
cerevisiae) 		PF05719
(GPP34) 		4 ARG A 340
ARG A 126
ASP A 122
VAL A 334
 None
 1.10A 4xqeB-2ziiA:
undetectable		 4xqeB-2ziiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a9i HOMOCITRATE SYNTHASE

(Thermus
thermophilus) 		PF00682
(HMGL-like) 		4 ARG A  12
ASP A  92
VAL A 218
ASP A 219
 LYS  A 378 (-3.4A)
LYS  A 378 (-3.3A)
None
None
 1.37A 4xqeB-3a9iA:
undetectable		 4xqeB-3a9iA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3auo DNA POLYMERASE BETA
FAMILY (X FAMILY)

(Thermus
thermophilus) 		PF14520
(HHH_5)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb) 		4 ARG A 472
ARG A 548
ASP A 194
ASP A 512
 None
 1.25A 4xqeB-3auoA:
undetectable		 4xqeB-3auoA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ctp PERIPLASMIC BINDING
PROTEIN/LACI
TRANSCRIPTIONAL
REGULATOR

(Alkaliphilus
metalliredigens) 		PF13377
(Peripla_BP_3) 		4 ARG A 124
ARG A 190
ASP A 213
ASP A 267
 XLF  A 401 (-4.0A)
XLF  A 401 (-2.8A)
XLF  A 401 ( 4.3A)
XLF  A 401 (-2.8A)
 1.09A 4xqeB-3ctpA:
2.2		 4xqeB-3ctpA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6s ALLERGEN DER F I

(Dermatophagoides
farinae) 		PF00112
(Peptidase_C1) 		4 ARG A 100
ARG A 105
ARG A 103
ASP A  65
 SO4  A 225 ( 4.3A)
SO4  A 225 (-4.1A)
None
None
 1.30A 4xqeB-3d6sA:
undetectable		 4xqeB-3d6sA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fdh SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF12771
(SusD-like_2) 		4 ARG A  43
ASP A 123
VAL A 128
ASP A 197
 None
 1.30A 4xqeB-3fdhA:
undetectable		 4xqeB-3fdhA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fok UNCHARACTERIZED
PROTEIN CGL0159

(Corynebacterium
glutamicum) 		no annotation 4 ARG A  32
ARG A  35
VAL A 142
ASP A 143
 None
 1.34A 4xqeB-3fokA:
undetectable		 4xqeB-3fokA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3git CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT ALPHA

(Moorella
thermoacetica) 		PF03598
(CdhC) 		4 ARG A 488
ASP A 489
VAL A 531
ASP A 535
 None
None
SF4  A 738 (-4.2A)
None
 0.88A 4xqeB-3gitA:
undetectable		 4xqeB-3gitA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gqm CELL INHIBITING
FACTOR (CIFBP)

(Burkholderia
pseudomallei) 		PF16374
(CIF) 		4 ARG A 159
ARG A  15
VAL A 135
ASP A 150
 None
 1.36A 4xqeB-3gqmA:
undetectable		 4xqeB-3gqmA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gxk GOOSE-TYPE LYSOZYME
1

(Gadus morhua) 		PF01464
(SLT) 		4 ARG A  75
ASP A  24
VAL A 177
ASP A 176
 None
 1.24A 4xqeB-3gxkA:
undetectable		 4xqeB-3gxkA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hje 704AA LONG
HYPOTHETICAL
GLYCOSYLTRANSFERASE

(Sulfurisphaera
tokodaii) 		PF00128
(Alpha-amylase)
PF09196
(DUF1953) 		4 ARG A 588
ARG A 503
ASP A 595
VAL A 600
 None
 1.41A 4xqeB-3hjeA:
undetectable		 4xqeB-3hjeA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iuu PUTATIVE
METALLOPEPTIDASE

(Chelativorans
sp. BNC1) 		PF07171
(MlrC_C)
PF07364
(DUF1485) 		4 ARG A  92
ARG A 122
VAL A  84
ASP A  85
 None
 1.25A 4xqeB-3iuuA:
2.9		 4xqeB-3iuuA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Bartonella
henselae) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 ARG A  12
ASP A  50
VAL A 240
ASP A 315
 None
 1.39A 4xqeB-3l0dA:
10.7		 4xqeB-3l0dA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lib HYPOTHETICAL SENSORY
TRANSDUCTION
HISTIDINE KINASE

(Methanosarcina
mazei) 		PF02743
(dCache_1) 		4 ARG A  83
ARG A 130
ASP A 126
ASP A 116
 None
 1.39A 4xqeB-3libA:
undetectable		 4xqeB-3libA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m7n PUTATIVE
UNCHARACTERIZED
PROTEIN AF_0206

(Archaeoglobus
fulgidus) 		PF10447
(EXOSC1)
PF14382
(ECR1_N) 		4 ARG A 168
ARG A 140
ASP A 116
VAL A 151
 None
 1.29A 4xqeB-3m7nA:
undetectable		 4xqeB-3m7nA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oyt 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE I

(Yersinia pestis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 ARG A   3
ARG A 403
VAL A 289
ASP A 290
 None
 1.29A 4xqeB-3oytA:
undetectable		 4xqeB-3oytA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p3l CYTOCHROME P450

(Streptomyces
thioluteus) 		PF00067
(p450) 		4 ARG A  69
ASP A  97
VAL A  87
ASP A  88
 None
 1.39A 4xqeB-3p3lA:
undetectable		 4xqeB-3p3lA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r20 CYTIDYLATE KINASE

(Mycolicibacterium
smegmatis) 		PF02224
(Cytidylate_kin) 		4 ARG A 155
ARG A 132
ARG A 182
ASP A 186
 None
 1.13A 4xqeB-3r20A:
undetectable		 4xqeB-3r20A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rac HISTIDINE-TRNA
LIGASE

(Alicyclobacillus
acidocaldarius) 		PF13393
(tRNA-synt_His) 		4 ARG A 150
ARG A 165
ASP A 162
VAL A  48
 None
 1.39A 4xqeB-3racA:
undetectable		 4xqeB-3racA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3swd UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Escherichia
coli) 		PF00275
(EPSP_synthase) 		4 ARG A 120
ARG A 331
ARG A 371
ASP A 369
 EPZ  A 501 (-4.1A)
EPZ  A 501 ( 4.2A)
None
None
 1.36A 4xqeB-3swdA:
undetectable		 4xqeB-3swdA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t4j HISTIDINE KINASE 4

(Arabidopsis
thaliana) 		PF03924
(CHASE) 		4 ARG A 134
ARG A 390
ASP A 367
VAL A 139
 None
 1.12A 4xqeB-3t4jA:
undetectable		 4xqeB-3t4jA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tkt CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		4 ARG A 299
ARG A 136
ARG A 399
VAL A 391
 None
 1.38A 4xqeB-3tktA:
undetectable		 4xqeB-3tktA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uel POLY(ADP-RIBOSE)
GLYCOHYDROLASE

(Rattus
norvegicus) 		PF05028
(PARG_cat) 		4 ARG A 839
ARG A 737
ASP A 772
ASP A 821
 None
 1.38A 4xqeB-3uelA:
undetectable		 4xqeB-3uelA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v9e LACCASE

(Botrytis aclada) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ARG A  92
ASP A 480
VAL A  24
ASP A  23
 None
 1.40A 4xqeB-3v9eA:
undetectable		 4xqeB-3v9eA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE

(Sulfolobus
solfataricus) 		PF00128
(Alpha-amylase)
PF09071
(Alpha-amyl_C) 		4 ARG A 353
ASP A 285
VAL A 344
ASP A 309
 None
 1.39A 4xqeB-3vgfA:
undetectable		 4xqeB-3vgfA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE

(Plasmodium
falciparum) 		PF05424
(Duffy_binding) 		4 ARG A 272
ARG A 348
ASP A 274
ASP A 266
 None
 1.39A 4xqeB-3vuuA:
undetectable		 4xqeB-3vuuA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vuv ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE

(Plasmodium
falciparum) 		PF05424
(Duffy_binding) 		4 ARG A 272
ARG A 348
ASP A 274
ASP A 266
 None
 1.41A 4xqeB-3vuvA:
undetectable		 4xqeB-3vuvA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w0f ENDONUCLEASE 8-LIKE
3

(Mus musculus) 		PF06831
(H2TH) 		4 ARG A 176
ARG A 186
VAL A 181
ASP A 184
 None
 1.36A 4xqeB-3w0fA:
undetectable		 4xqeB-3w0fA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w3s TYPE-2 SERINE--TRNA
LIGASE

(Methanopyrus
kandleri) 		PF00587
(tRNA-synt_2b) 		4 ARG A 109
ARG A 112
ASP A 111
VAL A 135
 None
SO4  A2020 (-3.3A)
SO4  A2020 (-4.0A)
None
 1.15A 4xqeB-3w3sA:
undetectable		 4xqeB-3w3sA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfp POLY A POLYMERASE

(Aquifex
aeolicus;
synthetic
construct) 		PF01743
(PolyA_pol)
PF01966
(HD)
PF12627
(PolyA_pol_RNAbd) 		4 ARG A  45
ARG A 188
ARG A 132
ASP A 133
 SO4  A1001 (-2.8A)
SO4  A1001 (-3.6A)
None
None
 1.39A 4xqeB-3wfpA:
undetectable		 4xqeB-3wfpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zty MANNOSYL-3-PHOSPHOGL
YCERATE PHOSPHATASE

(Thermus
thermophilus) 		PF08282
(Hydrolase_3) 		4 ARG A 185
ARG A 195
VAL A 213
ASP A 214
 None
 1.30A 4xqeB-3ztyA:
4.9		 4xqeB-3ztyA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4de9 PUTATIVE
TRANSCRIPTIONAL
REGULATOR YWTF

(Bacillus
subtilis) 		PF03816
(LytR_cpsA_psr) 		4 ARG A 227
ARG A  95
ASP A  97
ASP A 119
 VTP  A 401 (-2.4A)
None
VTP  A 401 (-3.8A)
None
 1.07A 4xqeB-4de9A:
undetectable		 4xqeB-4de9A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dzi PUTATIVE TIM-BARREL
METAL-DEPENDENT
HYDROLASE

(Mycobacterium
avium) 		PF04909
(Amidohydro_2) 		4 ARG A 300
ARG A 265
ASP A 269
ASP A 264
 SO4  A 506 (-3.7A)
SO4  A 506 (-4.0A)
None
None
 1.10A 4xqeB-4dziA:
undetectable		 4xqeB-4dziA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fsf PENICILLIN-BINDING
PROTEIN 3

(Pseudomonas
aeruginosa) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		4 ARG A  62
ASP A 183
VAL A 170
ASP A 169
 None
 0.93A 4xqeB-4fsfA:
undetectable		 4xqeB-4fsfA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hhr ALPHA-DIOXYGENASE

(Arabidopsis
thaliana) 		PF03098
(An_peroxidase) 		4 ARG A  91
ARG A 566
VAL A 223
ASP A 164
 None
CL  A 711 (-3.3A)
None
CA  A 703 (-3.3A)
 1.28A 4xqeB-4hhrA:
undetectable		 4xqeB-4hhrA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kf7 NUP188

(Thermothelomyces
thermophila) 		PF10487
(Nup188) 		4 ARG A 185
ARG A 108
ARG A 104
ASP A 101
 None
 1.33A 4xqeB-4kf7A:
undetectable		 4xqeB-4kf7A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m0v EXONUCLEASE SUBUNIT
SBCD

(Escherichia
coli) 		PF00149
(Metallophos)
PF12320
(SbcD_C) 		4 ARG A 117
ASP A 119
VAL A  40
ASP A  41
 None
 1.25A 4xqeB-4m0vA:
undetectable		 4xqeB-4m0vA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mcx ANTIDOTE PROTEIN
KILLER PROTEIN

(Proteus
vulgaris) 		PF01381
(HTH_3)
PF05015
(HigB-like_toxin) 		4 ARG B  48
ARG B  33
ARG A  15
ASP A  19
 None
 1.33A 4xqeB-4mcxB:
undetectable		 4xqeB-4mcxB:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4okq HUT OPERON POSITIVE
REGULATORY PROTEIN

(Geobacillus
thermodenitrificans) 		PF09021
(HutP) 		4 ARG A 109
ARG A  71
VAL A  65
ASP A  72
 None
 0.94A 4xqeB-4okqA:
undetectable		 4xqeB-4okqA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2c CRISPR-ASSOCIATED
HELICASE CAS3

(Thermobaculum
terrenum) 		PF00271
(Helicase_C) 		4 ARG A 704
ARG A 564
ARG A 696
ASP A 673
 None
 1.25A 4xqeB-4q2cA:
undetectable		 4xqeB-4q2cA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rzm EPOXIDE HYDROLASE
LASB

(Streptomyces
lasaliensis) 		PF12680
(SnoaL_2) 		4 ARG A 209
ARG A 167
VAL A 257
ASP A 264
 None
 1.27A 4xqeB-4rzmA:
undetectable		 4xqeB-4rzmA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u7b MARINER MOS1
TRANSPOSASE

(Drosophila
mauritiana) 		PF01359
(Transposase_1) 		4 ARG A 132
ARG A 332
ASP A 279
VAL A 337
 None
 1.40A 4xqeB-4u7bA:
undetectable		 4xqeB-4u7bA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wis LIPID SCRAMBLASE

([Nectria]
haematococca) 		PF04547
(Anoctamin) 		4 ARG A 178
ARG A 117
ARG A  84
ASP A  87
 None
 1.21A 4xqeB-4wisA:
undetectable		 4xqeB-4wisA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z5r ANTI-IFN-A ANTIBODY
RONTALIZUMAB HEAVY
CHAIN MODULES VH AND
CH1 (FAB)

(Homo sapiens) 		no annotation 4 ARG K  38
ARG K  62
ARG K  83
ASP K  86
 None
 1.12A 4xqeB-4z5rK:
undetectable		 4xqeB-4z5rK:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z85 2-NITROBENZOATE
NITROREDUCTASE

(Pseudomonas
fluorescens) 		PF01613
(Flavin_Reduct) 		4 ARG A  99
ARG A 166
ASP A 134
ASP A  93
 None
 1.10A 4xqeB-4z85A:
undetectable		 4xqeB-4z85A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bn7 MALTODEXTRIN
GLUCOSIDASE

(Escherichia
coli) 		PF00128
(Alpha-amylase) 		4 ARG A 135
ASP A 178
VAL A 208
ASP A 131
 None
 1.22A 4xqeB-5bn7A:
undetectable		 4xqeB-5bn7A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cin FAB 4E10 HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ARG H  38
ARG H  62
ARG H  83
ASP H  86
 GOL  H 302 (-4.1A)
GOL  H 302 (-3.9A)
None
None
 1.19A 4xqeB-5cinH:
undetectable		 4xqeB-5cinH:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f1n MHC CLASS I ANTIGEN

(Canis lupus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 ARG A  82
ARG A  75
ASP A  79
VAL A  12
 None
 1.38A 4xqeB-5f1nA:
undetectable		 4xqeB-5f1nA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gjy MHC CLASS I ANTIGEN

(Anas
platyrhynchos) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 ARG A  84
ARG A  77
ASP A  81
VAL A  15
 None
 1.19A 4xqeB-5gjyA:
undetectable		 4xqeB-5gjyA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gkv ESTERASE A

(Caulobacter
vibrioides) 		PF00144
(Beta-lactamase) 		4 ARG A 176
ARG A  86
ASP A 185
VAL A 173
 None
 1.28A 4xqeB-5gkvA:
undetectable		 4xqeB-5gkvA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jp6 PUTATIVE
POLYSACCHARIDE
DEACETYLASE

(Bdellovibrio
bacteriovorus) 		PF01522
(Polysacc_deac_1) 		4 ARG A 125
ARG A 339
VAL A 117
ASP A 118
 None
 1.36A 4xqeB-5jp6A:
undetectable		 4xqeB-5jp6A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jsb INDUCED MYELOID
LEUKEMIA CELL
DIFFERENTIATION
PROTEIN MCL-1

(Homo sapiens) 		PF00452
(Bcl-2) 		4 ARG A 303
ASP A 172
VAL A 297
ASP A 296
 None
 1.29A 4xqeB-5jsbA:
undetectable		 4xqeB-5jsbA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ub6 PHOSPHATE-BINDING
PROTEIN

(Xanthomonas
citri) 		no annotation 4 ARG A 293
ARG A 120
VAL A 238
ASP A 121
 None
 1.23A 4xqeB-5ub6A:
undetectable		 4xqeB-5ub6A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5umh CATECHOL
1,2-DIOXYGENASE

(Burkholderia
multivorans) 		PF00775
(Dioxygenase_C)
PF04444
(Dioxygenase_N) 		4 ARG A 103
ASP A  92
VAL A 301
ASP A 298
 None
 1.11A 4xqeB-5umhA:
undetectable		 4xqeB-5umhA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ur0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Naegleria
gruberi) 		no annotation 4 ARG A  11
ASP A  48
VAL A 237
ASP A 313
 None
 1.41A 4xqeB-5ur0A:
10.6		 4xqeB-5ur0A:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vha DEAH
(ASP-GLU-ALA-HIS)
BOX POLYPEPTIDE 36

(Bos taurus) 		no annotation 4 ARG A 282
ARG A 304
ASP A 248
ASP A 189
 None
 1.37A 4xqeB-5vhaA:
2.1		 4xqeB-5vhaA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w3j TUBULIN BETA CHAIN

(Saccharomyces
cerevisiae) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		4 ARG B  77
ASP B  74
VAL B  66
ASP B  67
 None
 1.06A 4xqeB-5w3jB:
3.4		 4xqeB-5w3jB:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w40 POPP2 PROTEIN

(Ralstonia
solanacearum) 		PF03421
(Acetyltransf_14) 		4 ARG A 454
ASP A 182
VAL A 450
ASP A 320
 None
 1.40A 4xqeB-5w40A:
undetectable		 4xqeB-5w40A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wm9 RV0078

(Mycobacterium
tuberculosis) 		no annotation 4 ARG A  76
ARG A  24
ASP A 106
VAL A  68
 ARG  A  76 ( 0.6A)
ARG  A  24 ( 0.6A)
ASP  A 106 ( 0.6A)
VAL  A  68 ( 0.6A)
 1.33A 4xqeB-5wm9A:
undetectable		 4xqeB-5wm9A:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsy VOLTAGE-GATED SODIUM
CHANNEL BETA SUBUNIT
1

(Electrophorus
electricus) 		no annotation 4 ARG B  92
ARG B  88
VAL B 114
ASP B 118
 None
 1.32A 4xqeB-5xsyB:
undetectable		 4xqeB-5xsyB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yh3 EXTRACELLULAR
SERINE/THREONINE
PROTEIN KINASE
FAM20C

(Homo sapiens) 		no annotation 4 ARG C 502
ARG C 504
ASP C 573
VAL C 569
 None
 1.39A 4xqeB-5yh3C:
undetectable		 4xqeB-5yh3C:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli) 		no annotation 4 ARG A 920
ARG A 415
ASP A 164
ASP A 409
 None
 1.26A 4xqeB-6bogA:
undetectable		 4xqeB-6bogA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f3m -

(-) 		no annotation 4 ARG B 351
ARG B 315
ASP B 363
VAL B 317
 None
 1.36A 4xqeB-6f3mB:
8.2		 4xqeB-6f3mB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fu4 PROBABLE CHEMOTAXIS
TRANSDUCER

(Pseudomonas
aeruginosa) 		no annotation 4 ARG A 105
ARG A  91
ASP A 135
VAL A 127
 None
 1.40A 4xqeB-6fu4A:
undetectable		 4xqeB-6fu4A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g1i -

(-) 		no annotation 4 ARG A 284
ASP A 285
VAL A 308
ASP A 312
 None
 0.95A 4xqeB-6g1iA:
undetectable		 4xqeB-6g1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gun -

(-) 		no annotation 4 ARG A  72
ARG A 290
ASP A  75
ASP A 298
 None
 1.22A 4xqeB-6gunA:
undetectable		 4xqeB-6gunA:
undetectable