SIMILAR PATTERNS OF AMINO ACIDS FOR 4X3U_B_SVRB101

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pdq POLYCOMB PROTEIN

(Drosophila
melanogaster)
PF00385
(Chromo)
6 ARG A  35
TRP A  47
TYR A  54
THR A  56
TRP A  57
LEU A  64
None
0.73A 4x3uA-1pdqA:
7.8
4x3uA-1pdqA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pdq POLYCOMB PROTEIN

(Drosophila
melanogaster)
PF00385
(Chromo)
6 TRP A  47
TRP A  50
TYR A  54
THR A  56
TRP A  57
LEU A  64
None
0.64A 4x3uA-1pdqA:
7.8
4x3uA-1pdqA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pfb POLYCOMB PROTEIN

(Drosophila
melanogaster)
PF00385
(Chromo)
6 ARG A  35
TRP A  47
TYR A  54
THR A  56
TRP A  57
LEU A  64
None
0.79A 4x3uA-1pfbA:
8.7
4x3uA-1pfbA:
51.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pfb POLYCOMB PROTEIN

(Drosophila
melanogaster)
PF00385
(Chromo)
6 TRP A  47
TRP A  50
TYR A  54
THR A  56
TRP A  57
LEU A  64
None
0.68A 4x3uA-1pfbA:
8.7
4x3uA-1pfbA:
51.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b2t CHROMODOMAIN-HELICAS
E-DNA-BINDING
PROTEIN 1


(Homo sapiens)
PF00385
(Chromo)
6 ARG A  23
LEU A  61
TRP A  64
TRP A  67
THR A  73
TRP A  74
None
0.44A 4x3uA-2b2tA:
5.8
4x3uA-2b2tA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b2y CHROMODOMAIN-HELICAS
E-DNA-BINDING
PROTEIN 1


(Homo sapiens)
PF00385
(Chromo)
5 ARG C  23
LEU C  61
TRP C  64
THR C  73
TRP C  74
None
0.28A 4x3uA-2b2yC:
5.4
4x3uA-2b2yC:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2d9u CHROMOBOX PROTEIN
HOMOLOG 2 (ISOFORM
2)


(Homo sapiens)
PF00385
(Chromo)
5 ARG A  20
LEU A  29
TRP A  32
TRP A  35
TRP A  42
None
0.85A 4x3uA-2d9uA:
7.6
4x3uA-2d9uA:
58.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2d9u CHROMOBOX PROTEIN
HOMOLOG 2 (ISOFORM
2)


(Homo sapiens)
PF00385
(Chromo)
5 ARG A  20
LEU A  29
TRP A  32
TRP A  42
LEU A  49
None
1.08A 4x3uA-2d9uA:
7.6
4x3uA-2d9uA:
58.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2dnv CHROMOBOX PROTEIN
HOMOLOG 8


(Mus musculus)
PF00385
(Chromo)
5 LEU A  29
TRP A  32
TRP A  35
THR A  41
TRP A  42
None
0.53A 4x3uA-2dnvA:
4.7
4x3uA-2dnvA:
59.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2dnv CHROMOBOX PROTEIN
HOMOLOG 8


(Mus musculus)
PF00385
(Chromo)
5 TRP A  32
TRP A  35
THR A  41
TRP A  42
LEU A  49
None
0.79A 4x3uA-2dnvA:
4.7
4x3uA-2dnvA:
59.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h1e CHROMO DOMAIN
PROTEIN 1


(Saccharomyces
cerevisiae)
PF00385
(Chromo)
5 ARG A  22
LEU A  50
THR A  62
TRP A  63
LEU A  75
None
1.00A 4x3uA-2h1eA:
5.3
4x3uA-2h1eA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h1e CHROMO DOMAIN
PROTEIN 1


(Saccharomyces
cerevisiae)
PF00385
(Chromo)
5 ARG A  22
LEU A  50
TRP A  53
THR A  62
TRP A  63
None
0.26A 4x3uA-2h1eA:
5.3
4x3uA-2h1eA:
23.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2k1b CHROMOBOX PROTEIN
HOMOLOG 7


(Homo sapiens)
PF00385
(Chromo)
5 LEU A  22
TRP A  25
TYR A  32
THR A  34
TRP A  35
None
1.08A 4x3uA-2k1bA:
6.8
4x3uA-2k1bA:
78.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1b CHROMOBOX PROTEIN
HOMOLOG 7


(Homo sapiens)
PF00385
(Chromo)
5 LEU A  23
TRP A  26
TRP A  29
TRP A  36
LEU A  43
None
1.02A 4x3uA-2l1bA:
7.8
4x3uA-2l1bA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1b CHROMOBOX PROTEIN
HOMOLOG 7


(Homo sapiens)
PF00385
(Chromo)
6 LEU A  23
TRP A  26
TRP A  29
TYR A  33
THR A  35
TRP A  36
None
0.69A 4x3uA-2l1bA:
7.8
4x3uA-2l1bA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1b CHROMOBOX PROTEIN
HOMOLOG 7


(Homo sapiens)
PF00385
(Chromo)
5 LEU A  23
TYR A  33
THR A  35
TRP A  36
HIS A  41
None
0.77A 4x3uA-2l1bA:
7.8
4x3uA-2l1bA:
93.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cb5 FACT COMPLEX SUBUNIT
SPT16


(Schizosaccharomyces
pombe)
PF00557
(Peptidase_M24)
PF14826
(FACT-Spt16_Nlob)
5 ARG A  14
LEU A 173
TYR A  51
TRP A  60
LEU A 379
None
1.42A 4x3uA-3cb5A:
undetectable
4x3uA-3cb5A:
10.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3f2u CHROMOBOX PROTEIN
HOMOLOG 1


(Homo sapiens)
PF00385
(Chromo)
5 ARG A  12
LEU A  21
TRP A  24
THR A  33
TRP A  34
None
0.20A 4x3uA-3f2uA:
7.1
4x3uA-3f2uA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fdt CHROMOBOX PROTEIN
HOMOLOG 5


(Homo sapiens)
PF00385
(Chromo)
5 ARG A  13
LEU A  22
TRP A  25
THR A  34
TRP A  35
None
0.31A 4x3uA-3fdtA:
7.6
4x3uA-3fdtA:
39.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3gv6 CHROMOBOX PROTEIN
HOMOLOG 6


(Homo sapiens)
PF00385
(Chromo)
8 ARG A  20
LEU A  29
TRP A  32
TRP A  35
TYR A  39
THR A  41
TRP A  42
LEU A  49
None
0.68A 4x3uA-3gv6A:
9.3
4x3uA-3gv6A:
69.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3h91 CHROMOBOX PROTEIN
HOMOLOG 2


(Homo sapiens)
PF00385
(Chromo)
6 ARG A  21
LEU A  30
TRP A  33
TRP A  36
TRP A  43
LEU A  50
None
0.66A 4x3uA-3h91A:
8.4
4x3uA-3h91A:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3i8z E3 SUMO-PROTEIN
LIGASE CBX4


(Homo sapiens)
PF00385
(Chromo)
6 ARG A  20
LEU A  29
TRP A  32
TYR A  39
THR A  41
TRP A  42
None
0.60A 4x3uA-3i8zA:
4.9
4x3uA-3i8zA:
73.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3i90 CHROMOBOX PROTEIN
HOMOLOG 6


(Homo sapiens)
PF00385
(Chromo)
8 ARG A  20
LEU A  29
TRP A  32
TRP A  35
TYR A  39
THR A  41
TRP A  42
LEU A  49
None
0.64A 4x3uA-3i90A:
8.1
4x3uA-3i90A:
63.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3i91 CHROMOBOX PROTEIN
HOMOLOG 8


(Homo sapiens)
PF00385
(Chromo)
8 ARG A  20
LEU A  29
TRP A  32
TRP A  35
TYR A  39
THR A  41
TRP A  42
LEU A  49
None
0.75A 4x3uA-3i91A:
8.5
4x3uA-3i91A:
68.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hae CHROMODOMAIN Y-LIKE
PROTEIN 2


(Homo sapiens)
PF00385
(Chromo)
5 ARG A  16
LEU A  26
TRP A  29
THR A  38
TRP A  39
None
0.31A 4x3uA-4haeA:
4.3
4x3uA-4haeA:
35.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4quf RE36324P

(Drosophila
melanogaster)
PF00385
(Chromo)
5 ARG A  33
LEU A  42
TRP A  45
THR A  54
TRP A  55
None
0.23A 4x3uA-4qufA:
8.6
4x3uA-4qufA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4u68 RHINO

(Drosophila
melanogaster)
PF00385
(Chromo)
5 ARG A  33
LEU A  42
TRP A  45
THR A  54
TRP A  55
None
0.30A 4x3uA-4u68A:
8.6
4x3uA-4u68A:
40.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5e4w SIGNAL RECOGNITION
PARTICLE 43 KDA
PROTEIN,
CHLOROPLASTIC


(Arabidopsis
thaliana)
PF00385
(Chromo)
5 ARG C 329
LEU C 340
TRP C 343
THR C 350
TRP C 351
None
0.36A 4x3uA-5e4wC:
6.4
4x3uA-5e4wC:
38.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ejw CHROMOBOX PROTEIN
HOMOLOG 7


(Mus musculus)
PF00385
(Chromo)
9 ARG A  20
LEU A  29
TRP A  32
TRP A  35
TYR A  39
THR A  41
TRP A  42
HIS A  47
LEU A  49
None
None
5PZ  A 101 (-3.6A)
5PZ  A 101 (-4.1A)
None
5PZ  A 101 (-3.5A)
None
None
None
0.68A 4x3uA-5ejwA:
8.4
4x3uA-5ejwA:
92.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9g CHROMO
DOMAIN-CONTAINING
PROTEIN 1


(Saccharomyces
cerevisiae)
no annotation 6 ARG W 186
LEU W 214
TRP W 217
THR W 226
TRP W 227
LEU W 239
None
0.83A 4x3uA-5o9gW:
7.9
4x3uA-5o9gW:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ftx -

(-)
no annotation 5 LEU W 214
TRP W 217
THR W 226
TRP W 227
LEU W 239
None
0.76A 4x3uA-6ftxW:
4.7
4x3uA-6ftxW:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pdq POLYCOMB PROTEIN

(Drosophila
melanogaster)
PF00385
(Chromo)
5 TRP A  47
TRP A  50
TYR A  54
THR A  56
TRP A  57
None
0.77A 4x3uB-1pdqA:
8.8
4x3uB-1pdqA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pfb POLYCOMB PROTEIN

(Drosophila
melanogaster)
PF00385
(Chromo)
5 TRP A  47
TRP A  50
TYR A  54
THR A  56
TRP A  57
None
0.78A 4x3uB-1pfbA:
9.6
4x3uB-1pfbA:
51.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pie GALACTOKINASE

(Lactococcus
lactis)
PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C)
PF10509
(GalKase_gal_bdg)
5 ARG A 281
LEU A 256
THR A 240
HIS A  43
LEU A 182
None
None
None
GLA  A 400 (-3.6A)
GLA  A 400 ( 4.3A)
1.28A 4x3uB-1pieA:
undetectable
4x3uB-1pieA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b2t CHROMODOMAIN-HELICAS
E-DNA-BINDING
PROTEIN 1


(Homo sapiens)
PF00385
(Chromo)
6 ARG A  23
LEU A  61
TRP A  64
TRP A  67
THR A  73
TRP A  74
None
0.49A 4x3uB-2b2tA:
7.4
4x3uB-2b2tA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b2y CHROMODOMAIN-HELICAS
E-DNA-BINDING
PROTEIN 1


(Homo sapiens)
PF00385
(Chromo)
5 ARG C  23
LEU C  61
TRP C  64
THR C  73
TRP C  74
None
0.29A 4x3uB-2b2yC:
5.4
4x3uB-2b2yC:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2d9u CHROMOBOX PROTEIN
HOMOLOG 2 (ISOFORM
2)


(Homo sapiens)
PF00385
(Chromo)
6 ARG A  20
LEU A  29
TRP A  32
TRP A  35
TRP A  42
LEU A  49
None
0.82A 4x3uB-2d9uA:
8.0
4x3uB-2d9uA:
58.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2dnt CHROMODOMAIN
PROTEIN, Y
CHROMOSOME-LIKE,
ISOFORM B


(Homo sapiens)
PF00385
(Chromo)
5 LEU A  33
TRP A  36
THR A  45
TRP A  46
HIS A  51
None
0.83A 4x3uB-2dntA:
6.9
4x3uB-2dntA:
37.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2dnv CHROMOBOX PROTEIN
HOMOLOG 8


(Mus musculus)
PF00385
(Chromo)
5 LEU A  29
TRP A  32
TRP A  35
THR A  41
TRP A  42
None
0.55A 4x3uB-2dnvA:
5.2
4x3uB-2dnvA:
59.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dy7 CHROMO DOMAIN
PROTEIN 1


(Saccharomyces
cerevisiae)
PF00385
(Chromo)
5 LEU A 214
TRP A 217
THR A 226
TRP A 227
LEU A 239
None
0.87A 4x3uB-2dy7A:
4.0
4x3uB-2dy7A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h1e CHROMO DOMAIN
PROTEIN 1


(Saccharomyces
cerevisiae)
PF00385
(Chromo)
6 ARG A  22
LEU A  50
TRP A  53
THR A  62
TRP A  63
LEU A  75
None
0.65A 4x3uB-2h1eA:
4.8
4x3uB-2h1eA:
23.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1b CHROMOBOX PROTEIN
HOMOLOG 7


(Homo sapiens)
PF00385
(Chromo)
7 ARG A  16
LEU A  23
TRP A  26
TRP A  29
TYR A  33
THR A  35
TRP A  36
None
1.00A 4x3uB-2l1bA:
8.6
4x3uB-2l1bA:
93.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l1b CHROMOBOX PROTEIN
HOMOLOG 7


(Homo sapiens)
PF00385
(Chromo)
5 LEU A  23
TYR A  33
THR A  35
TRP A  36
HIS A  41
None
0.76A 4x3uB-2l1bA:
8.6
4x3uB-2l1bA:
93.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zu0 PROTEIN SUFD

(Escherichia
coli)
PF01458
(UPF0051)
5 ARG A 254
ARG A 285
TRP A  49
HIS A 128
LEU A  33
None
1.41A 4x3uB-2zu0A:
undetectable
4x3uB-2zu0A:
8.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3f2u CHROMOBOX PROTEIN
HOMOLOG 1


(Homo sapiens)
PF00385
(Chromo)
5 ARG A  12
LEU A  21
TRP A  24
THR A  33
TRP A  34
None
0.22A 4x3uB-3f2uA:
9.0
4x3uB-3f2uA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fdt CHROMOBOX PROTEIN
HOMOLOG 5


(Homo sapiens)
PF00385
(Chromo)
5 ARG A  13
LEU A  22
TRP A  25
THR A  34
TRP A  35
None
0.35A 4x3uB-3fdtA:
8.6
4x3uB-3fdtA:
39.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3gv6 CHROMOBOX PROTEIN
HOMOLOG 6


(Homo sapiens)
PF00385
(Chromo)
7 ARG A  20
LEU A  29
TRP A  32
TRP A  35
TYR A  39
THR A  41
TRP A  42
None
0.60A 4x3uB-3gv6A:
10.2
4x3uB-3gv6A:
69.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3h91 CHROMOBOX PROTEIN
HOMOLOG 2


(Homo sapiens)
PF00385
(Chromo)
5 ARG A  21
LEU A  30
TRP A  33
TRP A  36
TRP A  43
None
0.48A 4x3uB-3h91A:
9.6
4x3uB-3h91A:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3i8z E3 SUMO-PROTEIN
LIGASE CBX4


(Homo sapiens)
PF00385
(Chromo)
6 ARG A  20
LEU A  29
TRP A  32
TYR A  39
THR A  41
TRP A  42
None
0.92A 4x3uB-3i8zA:
5.3
4x3uB-3i8zA:
73.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3i8z E3 SUMO-PROTEIN
LIGASE CBX4


(Homo sapiens)
PF00385
(Chromo)
6 ARG A  20
TRP A  32
TRP A  35
TYR A  39
THR A  41
TRP A  42
None
1.05A 4x3uB-3i8zA:
5.3
4x3uB-3i8zA:
73.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3i90 CHROMOBOX PROTEIN
HOMOLOG 6


(Homo sapiens)
PF00385
(Chromo)
7 ARG A  20
LEU A  29
TRP A  32
TRP A  35
TYR A  39
THR A  41
TRP A  42
None
0.66A 4x3uB-3i90A:
9.1
4x3uB-3i90A:
63.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3i91 CHROMOBOX PROTEIN
HOMOLOG 8


(Homo sapiens)
PF00385
(Chromo)
6 ARG A  20
ARG A  22
LEU A  29
THR A  41
TRP A  42
LEU A  49
None
0.69A 4x3uB-3i91A:
9.7
4x3uB-3i91A:
68.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3i91 CHROMOBOX PROTEIN
HOMOLOG 8


(Homo sapiens)
PF00385
(Chromo)
7 ARG A  20
ARG A  22
LEU A  29
TRP A  32
TRP A  35
THR A  41
TRP A  42
None
0.75A 4x3uB-3i91A:
9.7
4x3uB-3i91A:
68.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3i91 CHROMOBOX PROTEIN
HOMOLOG 8


(Homo sapiens)
PF00385
(Chromo)
7 ARG A  20
LEU A  29
TRP A  32
TRP A  35
TYR A  39
THR A  41
TRP A  42
None
0.75A 4x3uB-3i91A:
9.7
4x3uB-3i91A:
68.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hae CHROMODOMAIN Y-LIKE
PROTEIN 2


(Homo sapiens)
PF00385
(Chromo)
6 ARG A  16
LEU A  26
TRP A  29
THR A  38
TRP A  39
LEU A  46
None
0.40A 4x3uB-4haeA:
4.6
4x3uB-4haeA:
35.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4quf RE36324P

(Drosophila
melanogaster)
PF00385
(Chromo)
5 ARG A  33
LEU A  42
TRP A  45
THR A  54
TRP A  55
None
0.25A 4x3uB-4qufA:
9.1
4x3uB-4qufA:
38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4u68 RHINO

(Drosophila
melanogaster)
PF00385
(Chromo)
5 ARG A  33
LEU A  42
TRP A  45
THR A  54
TRP A  55
None
0.33A 4x3uB-4u68A:
8.7
4x3uB-4u68A:
40.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d0f UNCHARACTERIZED
PROTEIN


([Candida]
glabrata)
PF06202
(GDE_C)
PF14699
(hGDE_N)
PF14701
(hDGE_amylase)
PF14702
(hGDE_central)
5 LEU A1493
THR A1494
TRP A1430
HIS A1478
LEU A1035
None
1.32A 4x3uB-5d0fA:
undetectable
4x3uB-5d0fA:
3.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5e4w SIGNAL RECOGNITION
PARTICLE 43 KDA
PROTEIN,
CHLOROPLASTIC


(Arabidopsis
thaliana)
PF00385
(Chromo)
5 ARG C 329
LEU C 340
TRP C 343
THR C 350
TRP C 351
None
0.34A 4x3uB-5e4wC:
6.1
4x3uB-5e4wC:
38.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ejw CHROMOBOX PROTEIN
HOMOLOG 7


(Mus musculus)
PF00385
(Chromo)
8 ARG A  20
LEU A  29
TRP A  32
TRP A  35
TYR A  39
THR A  41
TRP A  42
HIS A  47
None
None
5PZ  A 101 (-3.6A)
5PZ  A 101 (-4.1A)
None
5PZ  A 101 (-3.5A)
None
None
0.52A 4x3uB-5ejwA:
8.3
4x3uB-5ejwA:
92.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ejw CHROMOBOX PROTEIN
HOMOLOG 7


(Mus musculus)
PF00385
(Chromo)
8 ARG A  20
LEU A  29
TRP A  32
TYR A  39
THR A  41
TRP A  42
HIS A  47
LEU A  49
None
None
5PZ  A 101 (-3.6A)
None
5PZ  A 101 (-3.5A)
None
None
None
0.83A 4x3uB-5ejwA:
8.3
4x3uB-5ejwA:
92.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9g CHROMO
DOMAIN-CONTAINING
PROTEIN 1


(Saccharomyces
cerevisiae)
no annotation 5 ARG W 186
LEU W 214
THR W 226
TRP W 227
LEU W 239
None
0.83A 4x3uB-5o9gW:
8.2
4x3uB-5o9gW:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9g CHROMO
DOMAIN-CONTAINING
PROTEIN 1


(Saccharomyces
cerevisiae)
no annotation 5 ARG W 186
LEU W 214
TRP W 217
THR W 226
TRP W 227
None
0.56A 4x3uB-5o9gW:
8.2
4x3uB-5o9gW:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ftx -

(-)
no annotation 5 LEU W 214
TRP W 217
THR W 226
TRP W 227
LEU W 239
None
0.71A 4x3uB-6ftxW:
7.9
4x3uB-6ftxW:
undetectable