SIMILAR PATTERNS OF AMINO ACIDS FOR 4X3M_B_ADNB301_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1azz | COLLAGENASE (Leptucapugilator) |
PF00089(Trypsin) | 5 | PRO A 198LEU A 33ILE A 212LEU A 53THR A 54 | None | 1.22A | 4x3mB-1azzA:undetectable | 4x3mB-1azzA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d1t | ALCOHOLDEHYDROGENASE CLASSIV SIGMA CHAIN (Homo sapiens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | PRO A 243LEU A 200GLY A 199ILE A 241VAL A 197 | NoneNoneNAD A1377 ( 3.7A)NoneNone | 1.17A | 4x3mB-1d1tA:2.6 | 4x3mB-1d1tA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fiw | BETA-ACROSIN HEAVYCHAIN (Ovis aries) |
PF00089(Trypsin) | 5 | PRO A 198LEU A 33ILE A 212LEU A 53THR A 54 | None | 1.22A | 4x3mB-1fiwA:undetectable | 4x3mB-1fiwA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fuj | PR3 (Homo sapiens) |
PF00089(Trypsin) | 5 | PRO A 198LEU A 33ILE A 212LEU A 53THR A 54 | None | 1.26A | 4x3mB-1fujA:undetectable | 4x3mB-1fujA:21.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gz0 | HYPOTHETICALTRNA/RRNAMETHYLTRANSFERASEYJFH (Escherichiacoli) |
PF00588(SpoU_methylase)PF08032(SpoU_sub_bind) | 6 | GLY A 196ILE A 216MET A 218SER A 224LEU A 225VAL A 227 | None | 0.95A | 4x3mB-1gz0A:9.2 | 4x3mB-1gz0A:30.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gz0 | HYPOTHETICALTRNA/RRNAMETHYLTRANSFERASEYJFH (Escherichiacoli) |
PF00588(SpoU_methylase)PF08032(SpoU_sub_bind) | 5 | GLY A 201ILE A 216MET A 218SER A 224LEU A 225 | None | 0.96A | 4x3mB-1gz0A:9.2 | 4x3mB-1gz0A:30.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hyl | HYPODERMA LINEATUMCOLLAGENASE (Hypodermalineatum) |
PF00089(Trypsin) | 5 | PRO A 198LEU A 33GLY A 32LEU A 53THR A 54 | None | 1.17A | 4x3mB-1hylA:undetectable | 4x3mB-1hylA:20.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ipa | RNA 2'-O-RIBOSEMETHYLTRANSFERASE (Thermusthermophilus) |
PF00588(SpoU_methylase)PF08032(SpoU_sub_bind) | 6 | GLY A 215ILE A 235MET A 237SER A 243LEU A 244VAL A 246 | None | 0.74A | 4x3mB-1ipaA:30.4 | 4x3mB-1ipaA:53.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j0n | XANTHAN LYASE (Bacillus sp.GL1) |
PF02278(Lyase_8)PF02884(Lyase_8_C)PF08124(Lyase_8_N) | 5 | GLY A 194ILE A 202MET A 156VAL A 259THR A 262 | None | 1.10A | 4x3mB-1j0nA:undetectable | 4x3mB-1j0nA:17.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqo | PHOSPHOENOLPYRUVATECARBOXYLASE (Zea mays) |
PF00311(PEPcase) | 6 | LEU A 83GLY A 84ILE A 102LEU A 901VAL A 903THR A 900 | None | 1.14A | 4x3mB-1jqoA:2.3 | 4x3mB-1jqoA:15.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kig | FACTOR XA (Bos taurus) |
PF00089(Trypsin) | 5 | PRO H 198LEU H 33ILE H 212LEU H 53THR H 54 | None | 1.15A | 4x3mB-1kigH:undetectable | 4x3mB-1kigH:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r1a | HUMAN RHINOVIRUS 1ACOAT PROTEIN(SUBUNIT VP1)HUMAN RHINOVIRUS 1ACOAT PROTEIN(SUBUNIT VP2) (Rhinovirus A) |
PF00073(Rhv) | 5 | LEU 2 173GLY 2 177ILE 1 278VAL 1 257THR 1 276 | None | 1.23A | 4x3mB-1r1a2:undetectable | 4x3mB-1r1a2:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u3t | ALCOHOLDEHYDROGENASE ALPHACHAIN (Homo sapiens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | PRO A 243LEU A 200GLY A 199ILE A 241VAL A 197 | NoneNoneNAD A1377 (-3.5A)NoneNone | 1.26A | 4x3mB-1u3tA:2.3 | 4x3mB-1u3tA:22.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1v2x | TRNA (GM18)METHYLTRANSFERASE (Thermusthermophilus) |
PF00588(SpoU_methylase)PF12105(SpoU_methylas_C) | 6 | GLY A 122ILE A 142MET A 144SER A 150LEU A 151VAL A 153 | SAM A 400 (-3.2A)SAM A 400 (-3.6A)SAM A 400 (-3.3A)SAM A 400 ( 3.7A)SAM A 400 (-4.0A)SAM A 400 (-3.9A) | 0.41A | 4x3mB-1v2xA:16.9 | 4x3mB-1v2xA:30.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vpl | ABC TRANSPORTER,ATP-BINDING PROTEIN (Thermotogamaritima) |
PF00005(ABC_tran) | 5 | PRO A 37GLY A 210ILE A 35MET A 194LEU A 206 | None | 1.21A | 4x3mB-1vplA:undetectable | 4x3mB-1vplA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wyz | PUTATIVES-ADENOSYLMETHIONINE-DEPENDENTMETHYLTRANSFERASE (Bacteroidesthetaiotaomicron) |
no annotation | 5 | LEU A 231ILE A 201SER A 122LEU A 126VAL A 128 | None | 0.83A | 4x3mB-1wyzA:2.4 | 4x3mB-1wyzA:24.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1x7p | RRNAMETHYLTRANSFERASE (Streptomycesviridochromogenes) |
PF00588(SpoU_methylase) | 5 | GLY A 232ILE A 252MET A 254SER A 260LEU A 261 | SAM A 301 (-3.2A)SAM A 301 (-4.0A)SAM A 301 (-3.1A)SAM A 301 ( 3.7A)SAM A 301 (-4.1A) | 0.87A | 4x3mB-1x7pA:27.9 | 4x3mB-1x7pA:34.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zjr | TRNA(GUANOSINE-2'-O-)-METHYLTRANSFERASE (Aquifexaeolicus) |
PF00588(SpoU_methylase)PF12105(SpoU_methylas_C) | 6 | GLY A 126ILE A 146MET A 148SER A 154LEU A 155VAL A 157 | GOL A 529 (-4.0A)NoneNoneGOL A 529 (-3.5A)NoneGOL A 529 (-3.7A) | 0.61A | 4x3mB-1zjrA:15.4 | 4x3mB-1zjrA:24.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ddt | SPHINGOMYELINPHOSPHODIESTERASE (Bacillus cereus) |
PF03372(Exo_endo_phos) | 5 | LEU A 78GLY A 79ILE A 115LEU A 90VAL A 118 | None | 0.86A | 4x3mB-2ddtA:undetectable | 4x3mB-2ddtA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dm4 | SORTILIN-RELATEDRECEPTOR (Homo sapiens) |
PF00041(fn3) | 5 | PRO A 19GLY A 102ILE A 26LEU A 70VAL A 72 | None | 1.01A | 4x3mB-2dm4A:undetectable | 4x3mB-2dm4A:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ef4 | ARGINASE (Thermusthermophilus) |
PF00491(Arginase) | 5 | PRO A 90GLY A 102ILE A 91SER A 258LEU A 259 | None | 1.22A | 4x3mB-2ef4A:undetectable | 4x3mB-2ef4A:28.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ei8 | COAGULATION FACTORX, HEAVY CHAIN (Homo sapiens) |
PF00089(Trypsin) | 5 | PRO A 198LEU A 33ILE A 212LEU A 53THR A 54 | None | 1.14A | 4x3mB-2ei8A:undetectable | 4x3mB-2ei8A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ha8 | TAR (HIV-1) RNA LOOPBINDING PROTEIN (Homo sapiens) |
PF00588(SpoU_methylase) | 6 | LEU A 128GLY A 129ILE A 149SER A 157LEU A 158VAL A 160 | SAH A 401 ( 4.6A)SAH A 401 (-3.1A)SAH A 401 (-3.8A)SAH A 401 ( 3.8A)SAH A 401 (-4.3A)SAH A 401 (-3.6A) | 0.81A | 4x3mB-2ha8A:17.1 | 4x3mB-2ha8A:26.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2i6d | RNAMETHYLTRANSFERASE,TRMH FAMILY (Porphyromonasgingivalis) |
PF00588(SpoU_methylase) | 5 | LEU A 202GLY A 203ILE A 223LEU A 237VAL A 239 | None | 0.91A | 4x3mB-2i6dA:24.6 | 4x3mB-2i6dA:32.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2i6d | RNAMETHYLTRANSFERASE,TRMH FAMILY (Porphyromonasgingivalis) |
PF00588(SpoU_methylase) | 5 | LEU A 202ILE A 223SER A 236LEU A 237VAL A 239 | None | 0.93A | 4x3mB-2i6dA:24.6 | 4x3mB-2i6dA:32.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jh9 | VP4 CORE PROTEIN (Bluetonguevirus) |
PF05059(Orbi_VP4) | 5 | GLY A 439ILE A 424MET A 428LEU A 412THR A 413 | None | 1.22A | 4x3mB-2jh9A:undetectable | 4x3mB-2jh9A:15.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qfq | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Escherichiacoli) |
PF00275(EPSP_synthase) | 5 | PRO A 181GLY A 159ILE A 215MET A 208LEU A 177 | None | 1.24A | 4x3mB-2qfqA:undetectable | 4x3mB-2qfqA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsm | HEMAGGLUTININ-NEURAMINIDASE (Nipahhenipavirus) |
PF00423(HN) | 5 | PRO A 273LEU A 319GLY A 251VAL A 293THR A 317 | None | 1.05A | 4x3mB-2vsmA:undetectable | 4x3mB-2vsmA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xa7 | AP-2 COMPLEX SUBUNITBETA (Homo sapiens) |
PF01602(Adaptin_N) | 5 | LEU B 257GLY B 568ILE B 306LEU B 303VAL B 301 | None | 1.06A | 4x3mB-2xa7B:undetectable | 4x3mB-2xa7B:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xxl | GRAM-POSITIVESPECIFIC SERINEPROTEASE, ISOFORM B (Drosophilamelanogaster) |
PF00089(Trypsin)PF12032(CLIP) | 5 | PRO A 321LEU A 136ILE A 341LEU A 159THR A 160 | None | 1.19A | 4x3mB-2xxlA:undetectable | 4x3mB-2xxlA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a14 | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Thermotogamaritima) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 5 | LEU A 262ILE A 8LEU A 20VAL A 22THR A 19 | None | 1.17A | 4x3mB-3a14A:2.8 | 4x3mB-3a14A:24.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bry | TBUX (Ralstoniapickettii) |
PF03349(Toluene_X) | 5 | PRO A 34LEU A 39GLY A 38LEU A 225THR A 226 | None | 1.21A | 4x3mB-3bryA:undetectable | 4x3mB-3bryA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cex | UNCHARACTERIZEDPROTEIN (Enterococcusfaecalis) |
PF04978(DUF664) | 5 | LEU A 11ILE A 56LEU A 114VAL A 112THR A 115 | None | 0.95A | 4x3mB-3cexA:undetectable | 4x3mB-3cexA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cf4 | ACETYL-COADECARBOXYLASE/SYNTHASE ALPHA SUBUNIT (Methanosarcinabarkeri) |
PF03063(Prismane) | 5 | LEU A 245ILE A 340MET A 375LEU A 384VAL A 386 | None | 1.04A | 4x3mB-3cf4A:3.2 | 4x3mB-3cf4A:17.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cru | GLUTATHIONES-TRANSFERASECLASS-MU 26 KDAISOZYME (Schistosomajaponicum) |
PF02798(GST_N)PF14497(GST_C_3) | 5 | LEU A 5GLY A 6ILE A 75VAL A 14THR A 17 | None | 1.15A | 4x3mB-3cruA:undetectable | 4x3mB-3cruA:24.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dcm | UNCHARACTERIZEDPROTEIN TM_1570 (Thermotogamaritima) |
PF09936(Methyltrn_RNA_4) | 5 | LEU X 140GLY X 141ILE X 161LEU X 170VAL X 172 | SAM X5452 (-4.5A)SAM X5452 (-3.1A)SAM X5452 (-3.7A)SAM X5452 (-4.2A)SAM X5452 (-3.7A) | 0.96A | 4x3mB-3dcmX:12.9 | 4x3mB-3dcmX:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3etn | PUTATIVEPHOSPHOSUGARISOMERASE INVOLVEDIN CAPSULE FORMATION (Bacteroidesfragilis) |
PF01380(SIS) | 5 | LEU A 130GLY A 98LEU A 106VAL A 104THR A 107 | None | 1.26A | 4x3mB-3etnA:undetectable | 4x3mB-3etnA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gyq | RRNA(ADENOSINE-2'-O-)-METHYLTRANSFERASE (Streptomycescyaneus) |
PF00588(SpoU_methylase)PF04705(TSNR_N) | 5 | GLY A 218ILE A 238MET A 240LEU A 247VAL A 249 | SAM A 270 (-2.9A)SAM A 270 (-3.5A)SAM A 270 (-3.5A)SAM A 270 (-4.4A)SAM A 270 ( 4.2A) | 0.62A | 4x3mB-3gyqA:22.9 | 4x3mB-3gyqA:29.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gyq | RRNA(ADENOSINE-2'-O-)-METHYLTRANSFERASE (Streptomycescyaneus) |
PF00588(SpoU_methylase)PF04705(TSNR_N) | 5 | ILE A 238MET A 240SER A 246LEU A 247VAL A 249 | SAM A 270 (-3.5A)SAM A 270 (-3.5A)SAM A 270 (-2.8A)SAM A 270 (-4.4A)SAM A 270 ( 4.2A) | 0.78A | 4x3mB-3gyqA:22.9 | 4x3mB-3gyqA:29.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l8u | PUTATIVE RRNAMETHYLASE (Streptococcusmutans) |
PF00588(SpoU_methylase) | 5 | GLY A 117ILE A 138SER A 147LEU A 148THR A 153 | None | 0.59A | 4x3mB-3l8uA:17.2 | 4x3mB-3l8uA:23.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lpz | GET4 (YOR164CHOMOLOG) (Chaetomiumthermophilum) |
PF04190(DUF410) | 5 | LEU A 70GLY A 67ILE A 50LEU A 12THR A 31 | None | 1.11A | 4x3mB-3lpzA:undetectable | 4x3mB-3lpzA:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nip | 3-GUANIDINOPROPIONASE (Pseudomonasaeruginosa) |
PF00491(Arginase) | 5 | LEU A 268ILE A 209LEU A 217VAL A 219THR A 222 | None | 0.71A | 4x3mB-3nipA:undetectable | 4x3mB-3nipA:26.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3nk7 | 23S RRNAMETHYLTRANSFERASE (Streptomycesactuosus) |
PF00588(SpoU_methylase)PF04705(TSNR_N) | 6 | GLY A 218ILE A 238MET A 240SER A 246LEU A 247VAL A 249 | SAM A 770 (-3.0A)SAM A 770 (-3.8A)SAM A 770 (-3.3A)SAM A 770 (-3.9A)SAM A 770 (-4.5A)SAM A 770 (-3.7A) | 0.57A | 4x3mB-3nk7A:24.8 | 4x3mB-3nk7A:30.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p2c | PUTATIVE GLYCOSYLHYDROLASE (Bacteroidesovatus) |
PF06824(Glyco_hydro_125) | 5 | LEU A 195GLY A 118ILE A 208LEU A 143VAL A 141 | None | 1.16A | 4x3mB-3p2cA:undetectable | 4x3mB-3p2cA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qnq | PTS SYSTEM,CELLOBIOSE-SPECIFICIIC COMPONENT (Bacillus cereus) |
PF02378(PTS_EIIC) | 5 | LEU A 106GLY A 190ILE A 152VAL A 194THR A 110 | None | 1.22A | 4x3mB-3qnqA:undetectable | 4x3mB-3qnqA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rp2 | RAT MAST CELLPROTEASE II (Rattus rattus) |
PF00089(Trypsin) | 5 | PRO A 198LEU A 33ILE A 212LEU A 53THR A 54 | None | 1.21A | 4x3mB-3rp2A:undetectable | 4x3mB-3rp2A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s9b | VIPERA RUSSELLIPROTEINASE RVV-VGAMMA (Daboiasiamensis) |
PF00089(Trypsin) | 5 | PRO A 198LEU A 33ILE A 212LEU A 53THR A 54 | None | 1.16A | 4x3mB-3s9bA:undetectable | 4x3mB-3s9bA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t1p | ALPHA-1-ANTITRYPSIN (Homo sapiens) |
PF00079(Serpin) | 5 | LEU A 306GLY A 307ILE A 57MET A 351LEU A 299 | None | 1.19A | 4x3mB-3t1pA:undetectable | 4x3mB-3t1pA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t2n | SERINE PROTEASEHEPSIN (Homo sapiens) |
PF00089(Trypsin)PF09272(Hepsin-SRCR) | 5 | PRO A 356LEU A 180ILE A 374LEU A 199THR A 200 | None | 1.25A | 4x3mB-3t2nA:undetectable | 4x3mB-3t2nA:25.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ulk | KETOL-ACIDREDUCTOISOMERASE (Escherichiacoli) |
PF01450(IlvC)PF07991(IlvN) | 5 | LEU A 235GLY A 232ILE A 295LEU A 431VAL A 429 | LEU A 235 ( 0.5A)GLY A 232 ( 0.0A)ILE A 295 ( 0.6A)LEU A 431 ( 0.6A)VAL A 429 ( 0.6A) | 1.01A | 4x3mB-3ulkA:undetectable | 4x3mB-3ulkA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v10 | RHUSIOPATHIAESURFACE PROTEIN B (Erysipelothrixrhusiopathiae) |
PF05737(Collagen_bind) | 5 | LEU A 168GLY A 169ILE A 178SER A 86LEU A 92 | None | 1.10A | 4x3mB-3v10A:undetectable | 4x3mB-3v10A:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vk9 | GLUTATHIONES-TRANSFERASE DELTA (Bombyx mori) |
PF13417(GST_N_3)PF14497(GST_C_3) | 5 | LEU A 74SER A 160LEU A 159VAL A 17THR A 20 | None | 1.14A | 4x3mB-3vk9A:undetectable | 4x3mB-3vk9A:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zg8 | PENICILLIN-BINDINGPROTEIN 4 (Listeriamonocytogenes) |
PF00905(Transpeptidase)PF00912(Transgly) | 5 | LEU B 484GLY B 485ILE B 461LEU B 457VAL B 455 | None | 1.03A | 4x3mB-3zg8B:undetectable | 4x3mB-3zg8B:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zg8 | PENICILLIN-BINDINGPROTEIN 4 (Listeriamonocytogenes) |
PF00905(Transpeptidase)PF00912(Transgly) | 6 | PRO B 392LEU B 486GLY B 485ILE B 475MET B 500LEU B 399 | None | 1.43A | 4x3mB-3zg8B:undetectable | 4x3mB-3zg8B:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zgb | PHOSPHOENOLPYRUVATECARBOXYLASE (Flaveriapringlei) |
PF00311(PEPcase) | 5 | LEU A 79GLY A 80LEU A 895VAL A 897THR A 894 | None | 1.09A | 4x3mB-3zgbA:undetectable | 4x3mB-3zgbA:15.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bf7 | ARABINOGALACTANENDO-1,4-BETA-GALACTOSIDASE A (Aspergillusnidulans) |
PF07745(Glyco_hydro_53) | 5 | LEU A 80SER A 168LEU A 115VAL A 117THR A 114 | None | 1.23A | 4x3mB-4bf7A:2.3 | 4x3mB-4bf7A:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bl3 | PENICILLIN BINDINGPROTEIN 2 PRIME (Staphylococcusaureus) |
PF00905(Transpeptidase)PF03717(PBP_dimer)PF05223(MecA_N) | 5 | LEU A 408ILE A 618MET A 628SER A 536LEU A 532 | None | 1.15A | 4x3mB-4bl3A:undetectable | 4x3mB-4bl3A:17.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxw | FACTOR XA (Pseudonajatextilis) |
PF00089(Trypsin)PF14670(FXa_inhibition) | 5 | PRO A 365LEU A 187ILE A 379LEU A 207THR A 208 | None | 1.21A | 4x3mB-4bxwA:undetectable | 4x3mB-4bxwA:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hvn | HYPOTHETICAL PROTEIN (Catenulisporaacidiphila) |
PF12680(SnoaL_2) | 5 | PRO A 4GLY A 72ILE A 6LEU A 100THR A 102 | None | 1.19A | 4x3mB-4hvnA:undetectable | 4x3mB-4hvnA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ilq | CT771 (Chlamydiatrachomatis) |
PF00293(NUDIX) | 5 | PRO A 14GLY A 67ILE A 31VAL A 61THR A 64 | None | 1.26A | 4x3mB-4ilqA:undetectable | 4x3mB-4ilqA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jos | ADENOSYLHOMOCYSTEINENUCLEOSIDASE (Francisellaphilomiragia) |
PF01048(PNP_UDP_1) | 5 | LEU A 7GLY A 8ILE A 62LEU A 58THR A 59 | None | 1.19A | 4x3mB-4josA:undetectable | 4x3mB-4josA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lk4 | VESB PROTEASE (Vibrio cholerae) |
PF00089(Trypsin) | 5 | PRO A 224LEU A 50ILE A 236LEU A 74THR A 75 | None | 1.21A | 4x3mB-4lk4A:undetectable | 4x3mB-4lk4A:23.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m7f | FIBRINOGEN CDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00147(Fibrinogen_C) | 5 | LEU A 354GLY A 353ILE A 454LEU A 323THR A 324 | None | 1.17A | 4x3mB-4m7fA:undetectable | 4x3mB-4m7fA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mgg | MUCONATE LACTONIZINGENZYME (Labrenziaaggregata) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | LEU A 112GLY A 46ILE A 87MET A 91LEU A 76 | None | 1.26A | 4x3mB-4mggA:undetectable | 4x3mB-4mggA:24.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nvt | TRIOSEPHOSPHATEISOMERASE (Brucellamelitensis) |
PF00121(TIM) | 5 | LEU A 65GLY A 66ILE A 28SER A 238VAL A 46 | None | 1.22A | 4x3mB-4nvtA:3.4 | 4x3mB-4nvtA:25.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pg6 | HOMOSERINEDEHYDROGENASE (Staphylococcusaureus) |
PF00742(Homoserine_dh)PF03447(NAD_binding_3) | 5 | LEU A 158GLY A 156ILE A 208SER A 213LEU A 212 | None | 1.18A | 4x3mB-4pg6A:4.4 | 4x3mB-4pg6A:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pzk | TRNA(CYTIDINE(34)-2'-O)-METHYLTRANSFERASE (Bacillusanthracis) |
PF00588(SpoU_methylase) | 6 | GLY A 104ILE A 125MET A 127SER A 133LEU A 134THR A 139 | SAH A 201 (-3.1A)SAH A 201 (-3.9A)SAH A 201 (-3.3A)SAH A 201 ( 3.8A)SAH A 201 (-4.2A)SAH A 201 (-3.6A) | 0.70A | 4x3mB-4pzkA:17.2 | 4x3mB-4pzkA:25.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qmg | STAPHYLOCOCCALNUCLEASEDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00565(SNase) | 5 | GLY A 307ILE A 226SER A 224LEU A 223THR A 285 | None | 1.26A | 4x3mB-4qmgA:undetectable | 4x3mB-4qmgA:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wr4 | GLUTATHIONES-TRANSFERASECLASS-MU 26 KDAISOZYME (Schistosomajaponicum) |
PF02798(GST_N)PF14497(GST_C_3) | 5 | LEU A 4GLY A 5ILE A 74VAL A 13THR A 16 | BYR A 57 ( 4.4A)BYR A 32 ( 4.5A)BYR A 73 ( 4.3A)NoneNone | 1.15A | 4x3mB-4wr4A:undetectable | 4x3mB-4wr4A:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yji | ARYL ACYLAMIDASE (bacteriumCSBL00001) |
PF01425(Amidase) | 5 | PRO A 177LEU A 128ILE A 175VAL A 31THR A 34 | None | 1.22A | 4x3mB-4yjiA:undetectable | 4x3mB-4yjiA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yle | PERIPLASMIC BINDINGPROTEIN/LACITRANSCRIPTIONALREGULATOR (Burkholderiamultivorans) |
PF13407(Peripla_BP_4) | 5 | LEU A 157GLY A 154MET A 217LEU A 227VAL A 254 | None | 1.09A | 4x3mB-4yleA:4.4 | 4x3mB-4yleA:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5anb | EUKARYOTICTRANSLATIONINITIATION FACTOR 6 (Dictyosteliumdiscoideum) |
PF01912(eIF-6) | 5 | LEU I 81ILE I 97SER I 63LEU I 71VAL I 94 | None | 1.26A | 4x3mB-5anbI:undetectable | 4x3mB-5anbI:25.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5chs | RNA-DIRECTED RNAPOLYMERASE L (Indianavesiculovirus) |
PF00946(Mononeg_RNA_pol) | 5 | LEU A 297ILE A 351LEU A 347VAL A 345THR A 348 | None | 1.16A | 4x3mB-5chsA:undetectable | 4x3mB-5chsA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cju | ISOBUTYRYL-COAMUTASE FUSED (Cupriavidusmetallidurans) |
PF01642(MM_CoA_mutase)PF02310(B12-binding)PF03308(ArgK) | 5 | GLY A 648ILE A 687MET A 690LEU A1075THR A 631 | None | 1.26A | 4x3mB-5cjuA:undetectable | 4x3mB-5cjuA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5co4 | PUTATIVE TRNA(CYTIDINE(34)-2'-O)-METHYLTRANSFERASE (Thermusthermophilus) |
no annotation | 5 | GLY B 101ILE B 120MET B 122SER B 128LEU B 129 | MTA B 401 (-3.2A)MTA B 401 (-3.7A)MTA B 401 (-3.4A)MTA B 401 ( 3.9A)MTA B 401 (-4.3A) | 0.55A | 4x3mB-5co4B:18.0 | 4x3mB-5co4B:26.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5do7 | ATP-BINDING CASSETTESUB-FAMILY G MEMBER8 (Homo sapiens) |
PF00005(ABC_tran)PF01061(ABC2_membrane) | 5 | LEU B 534ILE B 646SER B 651LEU B 650VAL B 538 | None | 1.20A | 4x3mB-5do7B:undetectable | 4x3mB-5do7B:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fdn | PHOSPHOENOLPYRUVATECARBOXYLASE 3 (Arabidopsisthaliana) |
PF00311(PEPcase) | 5 | LEU A 79GLY A 80LEU A 898VAL A 900THR A 897 | None | 1.21A | 4x3mB-5fdnA:undetectable | 4x3mB-5fdnA:15.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gvt | PLASMA KALLIKREIN (Mus musculus) |
no annotation | 5 | PRO A 198LEU A 33ILE A 212LEU A 53THR A 54 | None | 1.24A | 4x3mB-5gvtA:undetectable | 4x3mB-5gvtA:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ic9 | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF04003(Utp12) | 5 | LEU A 906ILE A 877LEU A 873VAL A 871THR A 874 | None | 1.23A | 4x3mB-5ic9A:undetectable | 4x3mB-5ic9A:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ixd | TYROSINE-PROTEINKINASE JAK1 (Homo sapiens) |
no annotation | 5 | LEU A 155MET A 202SER A 262LEU A 266VAL A 268 | None | 1.11A | 4x3mB-5ixdA:undetectable | 4x3mB-5ixdA:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jtk | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
no annotation | 5 | PRO A 3LEU A 51GLY A 86ILE A 7VAL A 40 | None | 0.98A | 4x3mB-5jtkA:undetectable | 4x3mB-5jtkA:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxu | DYP-TYPE PEROXIDASEFAMILY (Thermomonosporacurvata) |
PF04261(Dyp_perox) | 5 | LEU A 143GLY A 142ILE A 387LEU A 251VAL A 384 | None | 1.06A | 4x3mB-5jxuA:undetectable | 4x3mB-5jxuA:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ks1 | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Vibriovulnificus) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 5 | LEU A 284ILE A 6LEU A 18VAL A 20THR A 17 | None | 1.16A | 4x3mB-5ks1A:2.3 | 4x3mB-5ks1A:24.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lta | PRE-MRNA-SPLICINGFACTOR ATP-DEPENDENTRNA HELICASE PRP43 (Chaetomiumthermophilum) |
PF00270(DEAD)PF00271(Helicase_C)PF04408(HA2)PF07717(OB_NTP_bind) | 5 | LEU A 518GLY A 519ILE A 637LEU A 535VAL A 533 | None | 1.06A | 4x3mB-5ltaA:undetectable | 4x3mB-5ltaA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n1x | B-CELL LYMPHOMA 6PROTEIN (Homo sapiens) |
PF00651(BTB) | 5 | PRO D 80LEU D 86ILE D 78VAL D 105THR D 108 | None | 1.10A | 4x3mB-5n1xD:undetectable | 4x3mB-5n1xD:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n72 | WIPA (Legionellapneumophila) |
no annotation | 5 | LEU A 178GLY A 394ILE A 276LEU A 287VAL A 392 | None | 1.05A | 4x3mB-5n72A:undetectable | 4x3mB-5n72A:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5thz | CURJ (Mooreaproducens) |
no annotation | 5 | LEU B 39GLY B 36ILE B 317LEU B 168THR B 131 | None | 1.20A | 4x3mB-5thzB:undetectable | 4x3mB-5thzB:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tov | ADENOSYLHOMOCYSTEINASE (Thermotogamaritima) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | LEU A 147GLY A 143ILE A 111SER A 39LEU A 118 | None | 1.12A | 4x3mB-5tovA:2.2 | 4x3mB-5tovA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tov | ADENOSYLHOMOCYSTEINASE (Thermotogamaritima) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | LEU A 147ILE A 111LEU A 118VAL A 120THR A 119 | None | 1.22A | 4x3mB-5tovA:2.2 | 4x3mB-5tovA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u7z | ACID CERAMIDASE (Homo sapiens) |
no annotation | 5 | LEU B 307GLY B 291ILE B 349MET B 354VAL B 316 | None | 1.13A | 4x3mB-5u7zB:undetectable | 4x3mB-5u7zB:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u84 | ACID CERAMIDASE (Balaenopteraacutorostrata) |
no annotation | 5 | LEU A 307GLY A 291ILE A 349MET A 354VAL A 316 | NoneNoneNoneNoneIOD A 417 ( 4.2A) | 1.17A | 4x3mB-5u84A:undetectable | 4x3mB-5u84A:11.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ucy | TUBULIN ALPHA CHAIN (Tetrahymenathermophila) |
PF00091(Tubulin)PF03953(Tubulin_C) | 5 | LEU A 149GLY A 111ILE A 93LEU A 117VAL A 115 | None | 1.15A | 4x3mB-5ucyA:undetectable | 4x3mB-5ucyA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w1e | PUTATIVETRANSCRIPTIONALREGULATOR (Streptomycescoelicolor) |
no annotation | 5 | GLY A 150ILE A 123SER A 111LEU A 112VAL A 234 | NoneNonePHB A 602 (-2.5A)NoneNone | 1.11A | 4x3mB-5w1eA:undetectable | 4x3mB-5w1eA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wno | RECEPTORTYROSINE-PROTEINKINASE LET-23 (Caenorhabditiselegans) |
no annotation | 5 | LEU A1137GLY A1133ILE A 994LEU A1011VAL A1070 | None | 1.14A | 4x3mB-5wnoA:undetectable | 4x3mB-5wnoA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xd7 | 3,6-ANHYDRO-ALPHA-L-GALACTONATECYCLOISOMERASE (Vibrio sp. EJY3) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | LEU A 115GLY A 47ILE A 84MET A 88LEU A 73 | None | 1.14A | 4x3mB-5xd7A:undetectable | 4x3mB-5xd7A:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xxi | CYTOCHROME P450 2C9 (Homo sapiens) |
no annotation | 5 | LEU A 445GLY A 442ILE A 359LEU A 361THR A 305 | NoneNoneNoneNoneHEM A 504 (-3.9A) | 0.85A | 4x3mB-5xxiA:undetectable | 4x3mB-5xxiA:18.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xxi | CYTOCHROME P450 2C9 (Homo sapiens) |
no annotation | 5 | PRO A 427LEU A 445GLY A 442LEU A 361THR A 305 | NoneNoneNoneNoneHEM A 504 (-3.9A) | 1.20A | 4x3mB-5xxiA:undetectable | 4x3mB-5xxiA:18.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | RIBOSOMAL PROTEINS13P/S18E, PUTATIVE (Trichomonasvaginalis) |
PF00416(Ribosomal_S13) | 5 | LEU S 105GLY S 106ILE S 35SER S 19LEU S 18 | None | 1.21A | 4x3mB-5xyiS:undetectable | 4x3mB-5xyiS:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yb7 | L-AMINO ACIDOXIDASE/MONOOXYGENASE (Pseudomonas sp.AIU 813) |
no annotation | 5 | PRO A 277LEU A 117MET A 65SER A 288LEU A 289 | None | 1.17A | 4x3mB-5yb7A:undetectable | 4x3mB-5yb7A:13.75 |