SIMILAR PATTERNS OF AMINO ACIDS FOR 4X20_B_LOCB502_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dmu | BGLI RESTRICTIONENDONUCLEASE (Bacillussubtilis) |
PF14562(Endonuc_BglI) | 5 | LEU A 155LEU A 261VAL A 292ALA A 238ILE A 288 | None | 1.01A | 4x20B-1dmuA:undetectable | 4x20B-1dmuA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e4a | L-FUCULOSE1-PHOSPHATE ALDOLASE (Escherichiacoli) |
PF00596(Aldolase_II) | 5 | CYH P 14LEU P 15LEU P 50VAL P 30ILE P 55 | BME P 303 (-2.0A)NoneNoneBME P 303 ( 4.8A)None | 0.99A | 4x20B-1e4aP:undetectable | 4x20B-1e4aP:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g65 | PROTEASOME COMPONENTPUP3 (Saccharomycescerevisiae) |
PF00227(Proteasome) | 5 | ALA I 158LEU I 160ALA I 173VAL I 175ALA I 15 | None | 0.88A | 4x20B-1g65I:undetectable | 4x20B-1g65I:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gz4 | NAD-DEPENDENT MALICENZYME (Homo sapiens) |
PF00390(malic)PF03949(Malic_M) | 5 | LEU A 512ALA A 293LEU A 291ALA A 444ILE A 390 | None | 1.02A | 4x20B-1gz4A:3.6 | 4x20B-1gz4A:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iy2 | ATP-DEPENDENTMETALLOPROTEASE FTSH (Thermusthermophilus) |
PF00004(AAA) | 5 | LEU A 283LEU A 311THR A 301ALA A 299VAL A 297 | None | 0.98A | 4x20B-1iy2A:0.0 | 4x20B-1iy2A:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j33 | COBT (Thermusthermophilus) |
PF02277(DBI_PRT) | 5 | LEU A 260ALA A 256ASN A 167ALA A 52ALA A 160 | None | 0.95A | 4x20B-1j33A:3.1 | 4x20B-1j33A:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jdi | L-RIBULOSE 5PHOSPHATE4-EPIMERASE (Escherichiacoli) |
PF00596(Aldolase_II) | 5 | LEU A 190ALA A 101THR A 145VAL A 94ALA A 175 | None | 1.02A | 4x20B-1jdiA:undetectable | 4x20B-1jdiA:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jg3 | PROTEIN-L-ISOASPARTATEO-METHYLTRANSFERASE (Pyrococcusfuriosus) |
PF01135(PCMT) | 5 | LEU A 89ASN A 88VAL A 80ALA A 81ILE A 163 | None | 0.97A | 4x20B-1jg3A:0.0 | 4x20B-1jg3A:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k3v | CAPSID PROTEIN VP2 (Ungulateprotoparvovirus1) |
PF00740(Parvo_coat) | 5 | LEU A 86ALA A 101LEU A 218ASN A 217ILE A 230 | None | 1.04A | 4x20B-1k3vA:0.0 | 4x20B-1k3vA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ks8 | ENDO-B-1,4-GLUCANASE (Nasutitermestakasagoensis) |
PF00759(Glyco_hydro_9) | 5 | LEU A 184LEU A 177ALA A 99LYS A 97ALA A 162 | None | 0.97A | 4x20B-1ks8A:undetectable | 4x20B-1ks8A:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kyh | HYPOTHETICAL 29.9KDA PROTEIN INSIGY-CYDD INTERGENICREGION (Bacillussubtilis) |
PF01256(Carb_kinase) | 5 | CYH A 227LEU A 55ALA A 100ALA A 30ILE A 126 | None | 0.94A | 4x20B-1kyhA:undetectable | 4x20B-1kyhA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mtp | SERINE PROTEINASEINHIBITOR (SERPIN),CHAIN A (Thermobifidafusca) |
PF00079(Serpin) | 5 | LEU A 145THR A 298ALA A 319ALA A 317ILE A 157 | None | 0.87A | 4x20B-1mtpA:undetectable | 4x20B-1mtpA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t6p | PHENYLALANINEAMMONIA-LYASE (Rhodotorulatoruloides) |
PF00221(Lyase_aromatic) | 5 | LEU A 386ASN A 420THR A 489ALA A 506ALA A 279 | None | 0.89A | 4x20B-1t6pA:undetectable | 4x20B-1t6pA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tig | TRANSLATIONINITIATION FACTOR 3 (Geobacillusstearothermophilus) |
PF00707(IF3_C) | 5 | CYH A 144LEU A 110ALA A 148ALA A 118ALA A 106 | None | 0.90A | 4x20B-1tigA:undetectable | 4x20B-1tigA:12.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tlt | PUTATIVEOXIDOREDUCTASE(VIRULENCE FACTORMVIM HOMOLOG) (Escherichiacoli) |
PF01408(GFO_IDH_MocA) | 5 | LEU A 164LEU A 98ALA A 99LEU A 102ALA A 292 | None | 1.05A | 4x20B-1tltA:4.2 | 4x20B-1tltA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1umf | CHORISMATE SYNTHASE (Helicobacterpylori) |
PF01264(Chorismate_synt) | 5 | CYH A 335LEU A 338THR A 298VAL A 293ALA A 204 | None | 1.04A | 4x20B-1umfA:undetectable | 4x20B-1umfA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vic | 3-DEOXY-MANNO-OCTULOSONATECYTIDYLYLTRANSFERASE (Haemophilusinfluenzae) |
PF02348(CTP_transf_3) | 5 | LEU A 116ALA A 117ASN A 91VAL A 95ALA A 190 | None | 1.03A | 4x20B-1vicA:undetectable | 4x20B-1vicA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vma | CELL DIVISIONPROTEIN FTSY (Thermotogamaritima) |
PF00448(SRP54)PF02881(SRP54_N) | 5 | LEU A 216LEU A 244THR A 221ALA A 230ILE A 255 | None | 0.89A | 4x20B-1vmaA:3.7 | 4x20B-1vmaA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w99 | PESTICIDIAL CRYSTALPROTEIN CRY4BA (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 5 | LEU A 517LEU A 511ALA A 495THR A 609ALA A 611 | None | 0.96A | 4x20B-1w99A:undetectable | 4x20B-1w99A:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zj9 | PROBABLEFERREDOXIN-DEPENDENTNITRITE REDUCTASENIRA (Mycobacteriumtuberculosis) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | LEU A 105ALA A 109LEU A 150THR A 158VAL A 133 | None | 1.01A | 4x20B-1zj9A:1.6 | 4x20B-1zj9A:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zkl | HIGH-AFFINITYCAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 7A (Homo sapiens) |
PF00233(PDEase_I) | 5 | LEU A 298LEU A 292LEU A 198ALA A 250ALA A 289 | None | 0.97A | 4x20B-1zklA:undetectable | 4x20B-1zklA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zu4 | FTSY (Mycoplasmamycoides) |
PF00448(SRP54)PF02881(SRP54_N) | 5 | LEU A 324LEU A 352THR A 329ALA A 338ILE A 363 | None | 1.01A | 4x20B-1zu4A:3.7 | 4x20B-1zu4A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d0o | DIOLDEHYDRATASE-REACTIVATING FACTOR SMALLSUBUNIT (Klebsiellaoxytoca) |
PF02288(Dehydratase_MU) | 5 | ALA B 54THR B 98ALA B 102VAL B 106ILE B 29 | None | 0.95A | 4x20B-2d0oB:undetectable | 4x20B-2d0oB:15.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dpw | HYPOTHETICAL PROTEINTTHA0179 (Thermusthermophilus) |
PF12804(NTP_transf_3) | 5 | LEU A 97ALA A 41ALA A 5VAL A 7ALA A 90 | None | 1.02A | 4x20B-2dpwA:undetectable | 4x20B-2dpwA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fy2 | CHOLINEO-ACETYLTRANSFERASE (Homo sapiens) |
PF00755(Carn_acyltransf) | 5 | LEU A 428LEU A 421ALA A 424ALA A 562ILE A 394 | None | 1.05A | 4x20B-2fy2A:undetectable | 4x20B-2fy2A:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h6e | D-ARABINOSE1-DEHYDROGENASE (Sulfolobussolfataricus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 226ASN A 177VAL A 173ALA A 239ILE A 199 | None | 0.98A | 4x20B-2h6eA:3.8 | 4x20B-2h6eA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hne | L-FUCONATEDEHYDRATASE (Xanthomonascampestris) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 6 | LEU A 153ALA A 156LEU A 313THR A 303ALA A 336ILE A 321 | None | 1.48A | 4x20B-2hneA:2.5 | 4x20B-2hneA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i0o | SER/THR PHOSPHATASE (Anophelesgambiae) |
PF00481(PP2C) | 5 | CYH A 428LEU A 515VAL A 420ALA A 411ILE A 504 | None | 0.91A | 4x20B-2i0oA:undetectable | 4x20B-2i0oA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m1x | TIRDOMAIN-CONTAININGADAPTER MOLECULE 1 (Homo sapiens) |
no annotation | 5 | LEU A 533LEU A 416THR A 426ALA A 450ILE A 453 | None | 0.96A | 4x20B-2m1xA:undetectable | 4x20B-2m1xA:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nc8 | LIPOPROTEIN LPPM (Mycobacteriumtuberculosis) |
no annotation | 5 | LEU A 164ALA A 125ALA A 30VAL A 28ILE A 44 | None | 0.99A | 4x20B-2nc8A:undetectable | 4x20B-2nc8A:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o2z | HYPOTHETICAL PROTEIN (Bacillushalodurans) |
PF01933(UPF0052) | 6 | LEU A 19ALA A 63LEU A 61VAL A 33ALA A 31ILE A 109 | None | 1.25A | 4x20B-2o2zA:4.8 | 4x20B-2o2zA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o78 | PUTATIVE HISTIDINEAMMONIA-LYASE (Rhodobactersphaeroides) |
PF00221(Lyase_aromatic) | 5 | CYH A 466LEU A 467ALA A 411ALA A 407ILE A 459 | None | 0.89A | 4x20B-2o78A:undetectable | 4x20B-2o78A:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oi6 | BIFUNCTIONAL PROTEINGLMU (Escherichiacoli) |
PF00132(Hexapep)PF12804(NTP_transf_3) | 5 | LEU A 338LEU A 367ALA A 361ALA A 342ILE A 378 | None | 0.97A | 4x20B-2oi6A:undetectable | 4x20B-2oi6A:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oi6 | BIFUNCTIONAL PROTEINGLMU (Escherichiacoli) |
PF00132(Hexapep)PF12804(NTP_transf_3) | 5 | LEU A 367ALA A 353ALA A 342VAL A 344ALA A 361 | None | 0.88A | 4x20B-2oi6A:undetectable | 4x20B-2oi6A:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pan | GLYOXYLATECARBOLIGASE (Escherichiacoli) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | LEU A 222LEU A 329VAL A 214ALA A 219ILE A 301 | None | 0.93A | 4x20B-2panA:undetectable | 4x20B-2panA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qo3 | ERYAII ERYTHROMYCINPOLYKETIDE SYNTHASEMODULES 3 AND 4 (Saccharopolysporaerythraea) |
PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | ALA A 208LEU A 151THR A 127ALA A 224ILE A 185 | None | 0.90A | 4x20B-2qo3A:undetectable | 4x20B-2qo3A:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qsj | DNA-BINDING RESPONSEREGULATOR, LUXRFAMILY (Ruegeriapomeroyi) |
PF00072(Response_reg) | 5 | ALA A 41LEU A 43ASN A 47ALA A 33ILE A 52 | None | 1.02A | 4x20B-2qsjA:4.4 | 4x20B-2qsjA:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qsj | DNA-BINDING RESPONSEREGULATOR, LUXRFAMILY (Ruegeriapomeroyi) |
PF00072(Response_reg) | 5 | ALA A 41LEU A 43ASN A 47VAL A 7ALA A 33 | None | 0.90A | 4x20B-2qsjA:4.4 | 4x20B-2qsjA:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rfa | TRANSIENT RECEPTORPOTENTIAL CATIONCHANNEL SUBFAMILY VMEMBER 6 (Mus musculus) |
PF12796(Ank_2)PF13637(Ank_4) | 5 | LEU A 137LEU A 132ALA A 120VAL A 106ALA A 141 | None | 0.93A | 4x20B-2rfaA:undetectable | 4x20B-2rfaA:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vz9 | FATTY ACID SYNTHASE (Sus scrofa) |
PF00107(ADH_zinc_N)PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF08242(Methyltransf_12)PF08659(KR)PF14765(PS-DH)PF16197(KAsynt_C_assoc) | 5 | LEU A1022ALA A1034LEU A1032ALA A1094ILE A1059 | None | 1.05A | 4x20B-2vz9A:undetectable | 4x20B-2vz9A:11.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wa0 | MELANOMA-ASSOCIATEDANTIGEN 4 (Homo sapiens) |
PF01454(MAGE) | 5 | LEU A 203ALA A 278LEU A 257ALA A 211ILE A 222 | None | 1.02A | 4x20B-2wa0A:undetectable | 4x20B-2wa0A:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wyx | BETA-LACTAMSE TOHO-1 (Escherichiacoli) |
PF13354(Beta-lactamase2) | 5 | LEU A 119ASN A 136ALA A 109ALA A 125ILE A 97 | None | 1.04A | 4x20B-2wyxA:undetectable | 4x20B-2wyxA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x05 | EXO-BETA-D-GLUCOSAMINIDASE (Amycolatopsisorientalis) |
PF00703(Glyco_hydro_2)PF02837(Glyco_hydro_2_N) | 5 | LEU A 292LEU A 295ALA A 245VAL A 269ALA A 270 | None | 1.03A | 4x20B-2x05A:undetectable | 4x20B-2x05A:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x5r | HYPOTHETICAL PROTEINORF126 (Pyrobaculumspherical virus) |
no annotation | 5 | LEU A 61ALA A 65ASN A 100ALA A 97VAL A 41 | None | 1.03A | 4x20B-2x5rA:undetectable | 4x20B-2x5rA:17.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yn2 | UNCHARACTERIZEDPROTEIN YNL108C (Saccharomycescerevisiae) |
PF00300(His_Phos_1) | 5 | LEU A 47ALA A 48THR A 162VAL A 166ALA A 9 | None | 1.02A | 4x20B-2yn2A:undetectable | 4x20B-2yn2A:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a24 | ALPHA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF10566(Glyco_hydro_97)PF14508(GH97_N)PF14509(GH97_C) | 6 | LEU A 185ALA A 222LEU A 220VAL A 197ALA A 152ILE A 207 | None | 1.06A | 4x20B-3a24A:undetectable | 4x20B-3a24A:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bcz | PROTEIN MEMO1 (Homo sapiens) |
PF01875(Memo) | 5 | LEU A 177ALA A 255LEU A 253ALA A 44ILE A 224 | None | 1.04A | 4x20B-3bczA:undetectable | 4x20B-3bczA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bz5 | INTERNALIN-J (Listeriamonocytogenes) |
PF12799(LRR_4) | 5 | LEU A 374ASN A 378ALA A 358ALA A 333ILE A 360 | None | 1.00A | 4x20B-3bz5A:undetectable | 4x20B-3bz5A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c10 | HISTONE DEACETYLASE7A (Homo sapiens) |
PF00850(Hist_deacetyl) | 5 | LEU A 839LEU A 837ALA A 798ALA A 854VAL A 856 | None | 1.00A | 4x20B-3c10A:undetectable | 4x20B-3c10A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fk5 | 3-OXOACYL-SYNTHASEIII (Xanthomonasoryzae) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | LEU A 137ALA A 76VAL A 198ALA A 201ILE A 78 | None | 0.91A | 4x20B-3fk5A:undetectable | 4x20B-3fk5A:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fww | BIFUNCTIONAL PROTEINGLMU (Yersinia pestis) |
PF00132(Hexapep)PF12804(NTP_transf_3) | 5 | LEU A 338LEU A 367ALA A 361ALA A 342ILE A 378 | None | 1.02A | 4x20B-3fwwA:undetectable | 4x20B-3fwwA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fww | BIFUNCTIONAL PROTEINGLMU (Yersinia pestis) |
PF00132(Hexapep)PF12804(NTP_transf_3) | 5 | LEU A 367ALA A 353ALA A 342VAL A 344ALA A 361 | None | 1.01A | 4x20B-3fwwA:undetectable | 4x20B-3fwwA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g40 | NA-K-CLCOTRANSPORTER (Methanosarcinaacetivorans) |
no annotation | 5 | LEU A 757ALA A 695LEU A 691ALA A 658ILE A 635 | None | 1.02A | 4x20B-3g40A:undetectable | 4x20B-3g40A:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gaz | ALCOHOLDEHYDROGENASESUPERFAMILY PROTEIN (Novosphingobiumaromaticivorans) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | CYH A 245LEU A 246THR A 181VAL A 163ILE A 156 | None | 1.02A | 4x20B-3gazA:undetectable | 4x20B-3gazA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i99 | UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINEREDUCTASE (Vibrio cholerae) |
PF01565(FAD_binding_4)PF02873(MurB_C) | 5 | LEU A 302LEU A 286LEU A 334ALA A 284ILE A 332 | PO4 A 359 (-4.6A)NoneNoneNoneNone | 1.00A | 4x20B-3i99A:undetectable | 4x20B-3i99A:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ib6 | UNCHARACTERIZEDPROTEIN (Listeriamonocytogenes) |
PF13419(HAD_2) | 5 | ALA A 108LEU A 106ALA A 116ALA A 53ILE A 135 | None | 0.96A | 4x20B-3ib6A:4.1 | 4x20B-3ib6A:15.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k1j | ATP-DEPENDENTPROTEASE LON (Thermococcusonnurineus) |
PF01078(Mg_chelatase)PF05362(Lon_C)PF13654(AAA_32) | 5 | LEU A 208ALA A 261LEU A 258ALA A 237ILE A 244 | None | 0.85A | 4x20B-3k1jA:undetectable | 4x20B-3k1jA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mdu | N-FORMIMINO-L-GLUTAMATE IMINOHYDROLASE (Pseudomonasaeruginosa) |
PF01979(Amidohydro_1) | 5 | LEU A 290LEU A 267ALA A 270ALA A 282ALA A 286 | None | 0.82A | 4x20B-3mduA:undetectable | 4x20B-3mduA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p2m | POSSIBLE HYDROLASE (Mycobacteriumtuberculosis) |
PF12697(Abhydrolase_6) | 5 | LEU A 109ALA A 144ALA A 69VAL A 67ALA A 74 | None | 0.95A | 4x20B-3p2mA:3.9 | 4x20B-3p2mA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pl2 | SUGAR KINASE,RIBOKINASE FAMILY (Corynebacteriumglutamicum) |
PF00294(PfkB) | 5 | CYH A 205LEU A 171ALA A 208ALA A 229VAL A 231 | None | 1.04A | 4x20B-3pl2A:undetectable | 4x20B-3pl2A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pr2 | TRYPTOPHAN SYNTHASEBETA CHAIN (Salmonellaenterica) |
PF00291(PALP) | 5 | LEU B 271ALA B 284THR B 199ALA B 191ILE B 238 | None | 1.02A | 4x20B-3pr2B:2.4 | 4x20B-3pr2B:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3twd | BIFUNCTIONAL PROTEINGLMU (Escherichiacoli) |
PF00132(Hexapep) | 5 | LEU A 338ALA A 336ALA A 361ALA A 342ILE A 378 | None | 0.91A | 4x20B-3twdA:undetectable | 4x20B-3twdA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3twd | BIFUNCTIONAL PROTEINGLMU (Escherichiacoli) |
PF00132(Hexapep) | 5 | LEU A 338LEU A 367ALA A 361ALA A 342ILE A 378 | None | 0.93A | 4x20B-3twdA:undetectable | 4x20B-3twdA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3twd | BIFUNCTIONAL PROTEINGLMU (Escherichiacoli) |
PF00132(Hexapep) | 5 | LEU A 367ALA A 353ALA A 342VAL A 344ALA A 361 | None | 0.93A | 4x20B-3twdA:undetectable | 4x20B-3twdA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zuz | PROTEIN SHQ1 (Saccharomycescerevisiae) |
PF04925(SHQ1) | 5 | LEU A 399LEU A 303THR A 371ALA A 391ILE A 369 | None | 0.98A | 4x20B-3zuzA:undetectable | 4x20B-3zuzA:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4akm | LYSOSOME-ASSOCIATEDMEMBRANEGLYCOPROTEIN 3 (Homo sapiens) |
PF01299(Lamp) | 5 | LEU A 360LEU A 292ASN A 291ALA A 270ILE A 244 | NoneNoneNAG A1379 (-2.0A)NoneNone | 1.00A | 4x20B-4akmA:undetectable | 4x20B-4akmA:15.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4con | ANAEROBICRIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE (Thermotogamaritima) |
PF13597(NRDD) | 5 | LEU A 83VAL A 408LYS A 403ALA A 407ILE A 372 | None | 0.99A | 4x20B-4conA:undetectable | 4x20B-4conA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e3w | ACID PHOSPHATASE (Francisellatularensis) |
PF00328(His_Phos_2) | 5 | ALA A 29LEU A 170THR A 182ALA A 190ILE A 209 | None | 0.87A | 4x20B-4e3wA:undetectable | 4x20B-4e3wA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0l | AMIDOHYDROLASE (Brucellaabortus) |
PF01979(Amidohydro_1) | 5 | LEU A 295LEU A 272ALA A 275ALA A 287ALA A 291 | None | 0.93A | 4x20B-4f0lA:undetectable | 4x20B-4f0lA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f92 | U5 SMALL NUCLEARRIBONUCLEOPROTEIN200 KDA HELICASE (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 6 | LEU B 500LEU B 488LEU B 651ALA B 513ALA B 492ILE B 613 | None | 1.25A | 4x20B-4f92B:undetectable | 4x20B-4f92B:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fmt | CHPT PROTEIN (Caulobactervibrioides) |
PF10090(HPTransfase) | 5 | LEU A 112ALA A 101ALA A 161ALA A 146ILE A 219 | None | 0.97A | 4x20B-4fmtA:undetectable | 4x20B-4fmtA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hum | MULTIDRUG EFFLUXPROTEIN (Neisseriagonorrhoeae) |
PF01554(MatE) | 6 | LEU A 84LEU A 163ALA A 82ALA A 76ALA A 160ILE A 250 | None | 1.16A | 4x20B-4humA:undetectable | 4x20B-4humA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ifr | 2-AMINO-3-CARBOXYMUCONATE 6-SEMIALDEHYDEDECARBOXYLASE (Pseudomonasfluorescens) |
PF04909(Amidohydro_2) | 6 | LEU A 126ALA A 162ALA A 133LYS A 131ALA A 129ILE A 172 | None | 1.47A | 4x20B-4ifrA:undetectable | 4x20B-4ifrA:19.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lhq | CAMELID NANOBODY (Vicugna pacos) |
PF07686(V-set) | 5 | CYH B 22LEU B 4ALA B 24ASN B 32ILE B 51 | None | 0.73A | 4x20B-4lhqB:undetectable | 4x20B-4lhqB:15.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ojz | PUTATIVE ALGINATELYASE (Saccharophagusdegradans) |
PF05426(Alginate_lyase)PF07940(Hepar_II_III) | 5 | LEU A 327THR A 352VAL A 362LYS A 357ALA A 361 | None | 1.05A | 4x20B-4ojzA:undetectable | 4x20B-4ojzA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ojz | PUTATIVE ALGINATELYASE (Saccharophagusdegradans) |
PF05426(Alginate_lyase)PF07940(Hepar_II_III) | 5 | THR A 352VAL A 362LYS A 357ALA A 361ILE A 349 | None | 1.03A | 4x20B-4ojzA:undetectable | 4x20B-4ojzA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qhr | ALANINE RACEMASE (Acinetobacterbaumannii) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 5 | ALA A 48LEU A 17ASN A 16VAL A 33ALA A 37 | NoneNoneNoneLLP A 34 ( 3.3A)None | 0.99A | 4x20B-4qhrA:undetectable | 4x20B-4qhrA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rnh | MOTILITY REGULATOR (Pseudomonasaeruginosa) |
PF00563(EAL)PF00990(GGDEF) | 5 | LEU A 986LEU A1063VAL A1039ALA A1040ILE A1085 | None | 0.95A | 4x20B-4rnhA:undetectable | 4x20B-4rnhA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u1r | ATP-DEPENDENT6-PHOSPHOFRUCTOKINASE, PLATELET TYPE (Homo sapiens) |
PF00365(PFK) | 5 | LEU A 636LEU A 556ALA A 597ALA A 600ILE A 320 | None | 1.02A | 4x20B-4u1rA:undetectable | 4x20B-4u1rA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u9p | UPF0264 PROTEINMJ1099 (Methanocaldococcusjannaschii) |
PF04476(4HFCP_synth) | 5 | LEU A 34ALA A 184VAL A 118ALA A 120ILE A 204 | None | 1.00A | 4x20B-4u9pA:undetectable | 4x20B-4u9pA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v0p | MELANOMA-ASSOCIATEDANTIGEN 3 (Homo sapiens) |
PF01454(MAGE) | 5 | LEU A 202ALA A 277LEU A 256ALA A 210ILE A 221 | None | 1.01A | 4x20B-4v0pA:undetectable | 4x20B-4v0pA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v2i | ESTERASE/LIPASE (Thalassospirasp. GB04J01) |
PF07859(Abhydrolase_3) | 5 | LEU A 314ALA A 107LEU A 103ALA A 155ALA A 181 | None | 1.00A | 4x20B-4v2iA:3.8 | 4x20B-4v2iA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xjn | NUCLEOCAPSID (Mammalianrubulavirus 5) |
PF00973(Paramyxo_ncap) | 5 | LEU A 73THR A 178ALA A 174VAL A 170ILE A 219 | None | 0.99A | 4x20B-4xjnA:undetectable | 4x20B-4xjnA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zpx | ATP-DEPENDENTPROTEASE LON (Thermococcusonnurineus) |
PF01078(Mg_chelatase)PF13654(AAA_32) | 5 | LEU A 208ALA A 261LEU A 258ALA A 237ILE A 244 | None | 0.85A | 4x20B-4zpxA:undetectable | 4x20B-4zpxA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5isv | RIBOSOMAL-PROTEIN-ALANINEACETYLTRANSFERASE (Escherichiacoli) |
PF00583(Acetyltransf_1) | 6 | LEU A 45ALA A 83LEU A 85THR A 57VAL A 71ALA A 53 | None | 1.42A | 4x20B-5isvA:undetectable | 4x20B-5isvA:15.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5izn | 50S RIBOSOMALPROTEIN L25 (Vibriovulnificus) |
PF01386(Ribosomal_L25p) | 5 | LEU A 19ALA A 15LEU A 11ALA A 38ALA A 40 | None | 1.04A | 4x20B-5iznA:undetectable | 4x20B-5iznA:12.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n3u | PHYCOCYANOBILINLYASE SUBUNIT ALPHA (Nostoc sp. PCC7120) |
no annotation | 5 | LEU A 84ALA A 80LEU A 41ALA A 58ILE A 23 | None | 0.99A | 4x20B-5n3uA:undetectable | 4x20B-5n3uA:11.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5n | TUBULIN BETA CHAIN (Homo sapiens) |
no annotation | 5 | THR B 314ALA B 316VAL B 318ALA B 354ILE B 378 | None | 0.61A | 4x20B-5n5nB:53.6 | 4x20B-5n5nB:97.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n8p | S-LAYER PROTEIN (Caulobactervibrioides) |
PF00353(HemolysinCabind) | 5 | LEU A 930THR A 985VAL A 989ALA A 976ILE A1005 | None | 0.98A | 4x20B-5n8pA:undetectable | 4x20B-5n8pA:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n97 | S-LAYER PROTEIN RSAA (Caulobactervibrioides) |
PF00353(HemolysinCabind) | 5 | LEU A 930THR A 985VAL A 989ALA A 976ILE A1005 | None | 0.98A | 4x20B-5n97A:undetectable | 4x20B-5n97A:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tjr | METHYLMALONATE-SEMIALDEHYDEDEHYDROGENASE (Pseudomonas sp.AAC) |
PF00171(Aldedh) | 5 | LEU A 211ALA A 143LEU A 171ASN A 199ALA A 207 | None | 0.95A | 4x20B-5tjrA:undetectable | 4x20B-5tjrA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tvd | TM16 (Trichuris muris) |
PF01161(PBP) | 5 | CYH A 29LEU A 28LEU A 56ALA A 31VAL A 126 | None | 0.89A | 4x20B-5tvdA:undetectable | 4x20B-5tvdA:17.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vst | BILIARY GLYCOPROTEIN (Mus musculus) |
PF07686(V-set)PF13927(Ig_3) | 5 | LEU A 20THR A 98ALA A 100VAL A 102ILE A 88 | NAG A 301 (-4.8A)NoneNoneNoneNone | 0.97A | 4x20B-5vstA:undetectable | 4x20B-5vstA:19.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5w3j | TUBULIN BETA CHAIN (Saccharomycescerevisiae) |
PF00091(Tubulin)PF03953(Tubulin_C) | 5 | LEU B 253ASN B 256THR B 312ALA B 314ILE B 368 | None | 0.86A | 4x20B-5w3jB:53.5 | 4x20B-5w3jB:75.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wo6 | TRANSIENT RECEPTORPOTENTIAL CATIONCHANNEL SUBFAMILY VMEMBER 6 (Rattusnorvegicus) |
PF00520(Ion_trans)PF12796(Ank_2)PF13637(Ank_4) | 5 | LEU A 136ALA A 135ASN A 92ALA A 86ALA A 120 | LEU A 136 ( 0.6A)ALA A 135 ( 0.0A)ASN A 92 ( 0.6A)ALA A 86 ( 0.0A)ALA A 120 ( 0.0A) | 1.00A | 4x20B-5wo6A:undetectable | 4x20B-5wo6A:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wo6 | TRANSIENT RECEPTORPOTENTIAL CATIONCHANNEL SUBFAMILY VMEMBER 6 (Rattusnorvegicus) |
PF00520(Ion_trans)PF12796(Ank_2)PF13637(Ank_4) | 5 | LEU A 137LEU A 132ALA A 120VAL A 106ALA A 141 | LEU A 137 ( 0.6A)LEU A 132 ( 0.6A)ALA A 120 ( 0.0A)VAL A 106 ( 0.6A)ALA A 141 ( 0.0A) | 0.99A | 4x20B-5wo6A:undetectable | 4x20B-5wo6A:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wqw | N-ACETYLGLUCOSAMINIDASE (Clostridiumperfringens) |
PF01832(Glucosaminidase) | 5 | CYH A 969LEU A 970LEU A1020ALA A 954ALA A1059 | NoneNoneEDO A1202 (-3.8A)NoneEDO A1202 (-4.0A) | 0.88A | 4x20B-5wqwA:undetectable | 4x20B-5wqwA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b5d | MEIOTIC SPINDLEFORMATION PROTEINMEI-1 (Caenorhabditiselegans) |
no annotation | 5 | LEU A 318LEU A 349ALA A 337VAL A 335ALA A 228 | None | 0.95A | 4x20B-6b5dA:undetectable | 4x20B-6b5dA:11.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d6q | EXOSOME COMPLEXEXONUCLEASE RRP44 (Homo sapiens) |
no annotation | 5 | LEU K 551ALA K 507LEU K 558VAL K 555ILE K 459 | None | 1.04A | 4x20B-6d6qK:undetectable | 4x20B-6d6qK:10.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6esl | BACTERIAL LEUCYLAMINOPEPTIDASE (Legionellapneumophila) |
no annotation | 5 | LEU A 300ALA A 264VAL A 266ALA A 332ILE A 189 | None | 0.93A | 4x20B-6eslA:3.3 | 4x20B-6eslA:11.03 |