SIMILAR PATTERNS OF AMINO ACIDS FOR 4W5N_A_IPHA902_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ad9 IGG CTM01 FAB (LIGHT
CHAIN)

(Homo sapiens) 		no annotation 4 LEU L  27
LYS L  27
LEU L  92
GLU L  93
 None
 0.87A 4w5nA-1ad9L:
undetectable		 4w5nA-1ad9L:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1btc BETA-AMYLASE

(Glycine max) 		PF01373
(Glyco_hydro_14) 		4 LEU A 339
ILE A 338
LYS A 295
GLU A 380
 None
 0.79A 4w5nA-1btcA:
2.0		 4w5nA-1btcA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ct9 ASPARAGINE
SYNTHETASE B

(Escherichia
coli) 		PF00733
(Asn_synthase)
PF13537
(GATase_7) 		4 LEU A 140
ILE A 142
LYS A 406
TYR A 191
 None
 0.90A 4w5nA-1ct9A:
0.0		 4w5nA-1ct9A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eb3 5-AMINOLAEVULINIC
ACID DEHYDRATASE

(Saccharomyces
cerevisiae) 		PF00490
(ALAD) 		4 LEU A  45
ILE A  47
LEU A  71
TYR A  74
 None
 0.92A 4w5nA-1eb3A:
undetectable		 4w5nA-1eb3A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h7g 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE

(Escherichia
coli) 		PF02348
(CTP_transf_3) 		4 LEU A  22
ILE A  24
LEU A 230
GLU A 231
 None
 0.76A 4w5nA-1h7gA:
2.1		 4w5nA-1h7gA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iab ASTACIN

(Astacus astacus) 		PF01400
(Astacin) 		4 LEU A  94
ILE A  98
LEU A  37
GLU A  38
 None
 0.81A 4w5nA-1iabA:
undetectable		 4w5nA-1iabA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mow CHIMERA OF HOMING
ENDONUCLEASE I-DMOI
AND DNA ENDONUCLEASE
I-CREI

(Desulfurococcus
mucosus;
Chlamydomonas
reinhardtii) 		PF00961
(LAGLIDADG_1)
PF14528
(LAGLIDADG_3) 		4 LEU A  59
ILE A  60
LEU A  87
TYR A  90
 None
 0.88A 4w5nA-1mowA:
0.3		 4w5nA-1mowA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n21 (+)-BORNYL
DIPHOSPHATE SYNTHASE

(Salvia
officinalis) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 LEU A 113
ILE A 110
LEU A  97
GLU A 125
 None
 0.86A 4w5nA-1n21A:
0.0		 4w5nA-1n21A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nln ADENAIN

(Human
mastadenovirus
C) 		PF00770
(Peptidase_C5) 		4 LEU A 107
ILE A 105
LEU A  92
GLU A  89
 None
 0.94A 4w5nA-1nlnA:
undetectable		 4w5nA-1nlnA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1npy HYPOTHETICAL
SHIKIMATE
5-DEHYDROGENASE-LIKE
PROTEIN HI0607

(Haemophilus
influenzae) 		PF08501
(Shikimate_dh_N) 		4 LEU A 259
ILE A 260
LEU A  27
TYR A  26
 None
 0.94A 4w5nA-1npyA:
undetectable		 4w5nA-1npyA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nyq THREONYL-TRNA
SYNTHETASE 1

(Staphylococcus
aureus) 		PF00587
(tRNA-synt_2b)
PF02824
(TGS)
PF03129
(HGTP_anticodon)
PF07973
(tRNA_SAD) 		4 ILE A 550
LYS A 628
LEU A 569
GLU A 568
 None
 0.87A 4w5nA-1nyqA:
undetectable		 4w5nA-1nyqA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1odo PUTATIVE CYTOCHROME
P450 154A1

(Streptomyces
coelicolor) 		PF00067
(p450) 		4 LEU A 237
ILE A 240
LEU A 191
TYR A 192
 None
 0.93A 4w5nA-1odoA:
undetectable		 4w5nA-1odoA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uok OLIGO-1,6-GLUCOSIDAS
E

(Bacillus cereus) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		4 LEU A 531
ILE A 532
LEU A 470
GLU A 469
 None
 0.79A 4w5nA-1uokA:
2.5		 4w5nA-1uokA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vl2 ARGININOSUCCINATE
SYNTHASE

(Thermotoga
maritima) 		PF00764
(Arginosuc_synth) 		4 LEU A 221
ILE A 223
LEU A 252
TYR A 251
 None
 0.94A 4w5nA-1vl2A:
3.4		 4w5nA-1vl2A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xzq PROBABLE TRNA
MODIFICATION GTPASE
TRME

(Thermotoga
maritima) 		PF01926
(MMR_HSR1)
PF10396
(TrmE_N)
PF12631
(MnmE_helical) 		4 LEU A 160
ILE A 161
LEU A 423
GLU A 420
 None
 0.89A 4w5nA-1xzqA:
4.3		 4w5nA-1xzqA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b9l PROPHENOLOXIDASE
ACTIVATING FACTOR

(Holotrichia
diomphalia) 		PF00089
(Trypsin) 		4 LEU A 305
ILE A 304
LYS A 307
GLU A 162
 None
 0.79A 4w5nA-2b9lA:
undetectable		 4w5nA-2b9lA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cfm THERMOSTABLE DNA
LIGASE

(Pyrococcus
furiosus) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		4 LEU A  44
ILE A  45
LEU A   6
TYR A   3
 None
 0.94A 4w5nA-2cfmA:
undetectable		 4w5nA-2cfmA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h2q BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Trypanosoma
cruzi) 		PF00186
(DHFR_1)
PF00303
(Thymidylat_synt) 		4 LEU A 444
ILE A 445
LEU A 300
GLU A 497
 None
 0.82A 4w5nA-2h2qA:
undetectable		 4w5nA-2h2qA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j5c 1,8-CINEOLE SYNTHASE

(Salvia
fruticosa) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 LEU A 115
ILE A 112
LEU A  99
GLU A 127
 None
 0.94A 4w5nA-2j5cA:
undetectable		 4w5nA-2j5cA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l1a FORMIN-C

(Dictyostelium
discoideum) 		no annotation 4 ILE A  49
LYS A 100
GLU A  78
TYR A  76
 None
 0.97A 4w5nA-2l1aA:
undetectable		 4w5nA-2l1aA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lf2 UNCHARACTERIZED
PROTEIN

(Cytophaga
hutchinsonii) 		PF08327
(AHSA1) 		4 ILE A  18
LYS A  13
LEU A 139
GLU A 140
 None
 0.95A 4w5nA-2lf2A:
undetectable		 4w5nA-2lf2A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nz2 ARGININOSUCCINATE
SYNTHASE

(Homo sapiens) 		PF00764
(Arginosuc_synth) 		4 LEU A 223
ILE A 225
LEU A 254
TYR A 253
 None
 0.84A 4w5nA-2nz2A:
3.4		 4w5nA-2nz2A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odm UPF0358 PROTEIN
MW0995

(Staphylococcus
aureus) 		PF07408
(DUF1507) 		4 LEU A  25
ILE A  26
LEU A  45
TYR A  41
 None
 0.93A 4w5nA-2odmA:
undetectable		 4w5nA-2odmA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qdj RETINOBLASTOMA-ASSOC
IATED PROTEIN

(Homo sapiens) 		PF11934
(DUF3452) 		4 LEU A 223
ILE A 227
LEU A 277
GLU A 280
 None
 0.96A 4w5nA-2qdjA:
undetectable		 4w5nA-2qdjA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xpz LEUKOTRIENE A-4
HYDROLASE

(Saccharomyces
cerevisiae) 		PF01433
(Peptidase_M1)
PF09127
(Leuk-A4-hydro_C) 		4 LEU A 485
ILE A 484
LEU A 443
GLU A 448
 None
 0.89A 4w5nA-2xpzA:
3.4		 4w5nA-2xpzA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yt4 PROTEIN DGCR8

(Homo sapiens) 		PF00035
(dsrm) 		4 LEU A 516
ILE A 515
LEU A 573
GLU A 574
 None
 0.95A 4w5nA-2yt4A:
2.2		 4w5nA-2yt4A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zhy ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE,
PUTATIVE

(Burkholderia
thailandensis) 		PF01923
(Cob_adeno_trans) 		4 LEU A 138
ILE A 135
LEU A  76
GLU A  75
 None
 0.94A 4w5nA-2zhyA:
undetectable		 4w5nA-2zhyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c6f YETF PROTEIN

(Bacillus
subtilis) 		PF04239
(DUF421) 		4 LEU A 173
ILE A 174
LEU A 194
GLU A 191
 None
 0.74A 4w5nA-3c6fA:
undetectable		 4w5nA-3c6fA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c7m THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBA-LIKE

(Escherichia
coli) 		PF01323
(DSBA) 		4 ILE A 174
LYS A   1
LEU A 192
GLU A 191
 None
 0.83A 4w5nA-3c7mA:
undetectable		 4w5nA-3c7mA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cs3 SUGAR-BINDING
TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Enterococcus
faecalis) 		PF13377
(Peripla_BP_3) 		4 LEU A 115
ILE A 113
LEU A  77
TYR A  74
 None
 0.97A 4w5nA-3cs3A:
6.3		 4w5nA-3cs3A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dlv SIGNAL RECOGNITION
PARTICLE 19 KDA
PROTEIN

(Pyrococcus
furiosus) 		no annotation 4 LEU B  87
ILE B  88
LEU B  44
GLU B  43
 None
 0.81A 4w5nA-3dlvB:
undetectable		 4w5nA-3dlvB:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e21 FAS-ASSOCIATED
FACTOR 1

(Homo sapiens) 		PF14555
(UBA_4) 		4 LEU A  11
ILE A  10
LEU A  30
GLU A  31
 None
 0.95A 4w5nA-3e21A:
undetectable		 4w5nA-3e21A:
4.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hje 704AA LONG
HYPOTHETICAL
GLYCOSYLTRANSFERASE

(Sulfurisphaera
tokodaii) 		PF00128
(Alpha-amylase)
PF09196
(DUF1953) 		4 LEU A 535
ILE A 536
LEU A 485
TYR A 486
 None
 0.85A 4w5nA-3hjeA:
2.1		 4w5nA-3hjeA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hve GIGAXONIN

(Homo sapiens) 		PF00651
(BTB) 		4 LEU B  75
ILE B  78
LEU B 112
TYR B  54
 None
 0.96A 4w5nA-3hveB:
undetectable		 4w5nA-3hveB:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icq EXPORTIN-T

(Schizosaccharomyces
pombe) 		PF08389
(Xpo1) 		4 LEU T 624
ILE T 625
LEU T 578
GLU T 575
 None
 0.97A 4w5nA-3icqT:
undetectable		 4w5nA-3icqT:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3khk TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLATION SUBUNIT

(Methanosarcina
mazei) 		PF02384
(N6_Mtase)
PF12161
(HsdM_N) 		4 LEU A 297
LEU A 212
GLU A 209
TYR A 208
 None
 0.94A 4w5nA-3khkA:
undetectable		 4w5nA-3khkA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lq0 PROASTACIN

(Astacus astacus) 		PF01400
(Astacin) 		4 LEU A  94
ILE A  98
LEU A  37
GLU A  38
 None
None
None
GOL  A 502 (-2.9A)
 0.83A 4w5nA-3lq0A:
2.8		 4w5nA-3lq0A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m16 TRANSALDOLASE

(Oleispira
antarctica) 		PF00923
(TAL_FSA) 		4 LEU A  44
ILE A  43
LEU A 316
GLU A 317
 None
 0.98A 4w5nA-3m16A:
undetectable		 4w5nA-3m16A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q4n UNCHARACTERIZED
PROTEIN MJ0754

(Methanocaldococcus
jannaschii) 		PF09968
(DUF2202) 		4 LEU A  44
ILE A  46
LEU A 106
TYR A 157
 None
 0.97A 4w5nA-3q4nA:
undetectable		 4w5nA-3q4nA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q4o UNCHARACTERIZED
PROTEIN MJ0754

(Methanocaldococcus
jannaschii) 		PF09968
(DUF2202) 		4 LEU A  44
ILE A  46
LEU A 106
TYR A 157
 None
 0.87A 4w5nA-3q4oA:
undetectable		 4w5nA-3q4oA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r3j GLUTAMATE
DEHYDROGENASE

(Plasmodium
falciparum) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 LEU A  73
ILE A  70
LEU A  95
GLU A  92
 None
 0.97A 4w5nA-3r3jA:
2.6		 4w5nA-3r3jA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rr5 DNA LIGASE

(Thermococcus
sp. 1519) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		4 LEU A  55
ILE A  56
LEU A  17
TYR A  14
 None
 0.89A 4w5nA-3rr5A:
undetectable		 4w5nA-3rr5A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tlz MCCF

(Escherichia
coli) 		PF02016
(Peptidase_S66) 		4 LEU A 197
LYS A 195
LEU A 151
GLU A 147
 EDO  A 345 (-4.4A)
None
None
None
 0.97A 4w5nA-3tlzA:
3.1		 4w5nA-3tlzA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr6 O-METHYLTRANSFERASE

(Coxiella
burnetii) 		PF01596
(Methyltransf_3) 		4 LEU A 129
ILE A 130
LEU A 160
TYR A 138
 None
 0.73A 4w5nA-3tr6A:
2.2		 4w5nA-3tr6A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tt9 PLAKOPHILIN-2

(Homo sapiens) 		PF00514
(Arm) 		4 LEU A 398
ILE A 397
LEU A 436
GLU A 435
 None
 0.88A 4w5nA-3tt9A:
undetectable		 4w5nA-3tt9A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v0a NTNH

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07953
(Toxin_R_bind_N)
PF08470
(NTNH_C) 		4 LEU B 101
ILE B 102
LEU B 230
TYR B 234
 None
 0.84A 4w5nA-3v0aB:
2.9		 4w5nA-3v0aB:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vuo NTNHA

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07953
(Toxin_R_bind_N)
PF08470
(NTNH_C) 		5 LEU A 101
ILE A 102
LYS A 323
LEU A 230
TYR A 234
 None
 1.38A 4w5nA-3vuoA:
1.9		 4w5nA-3vuoA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x0y DSZC

(Rhodococcus
erythropolis) 		PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
PF08028
(Acyl-CoA_dh_2) 		4 LEU A 249
ILE A 253
LEU A 106
GLU A 105
 None
 0.92A 4w5nA-3x0yA:
undetectable		 4w5nA-3x0yA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zgq INTERFERON-INDUCED
PROTEIN WITH
TETRATRICOPEPTIDE
REPEATS 5

(Homo sapiens) 		PF07719
(TPR_2)
PF13181
(TPR_8)
PF13374
(TPR_10)
PF13424
(TPR_12) 		4 LEU A 242
ILE A 245
LEU A 271
TYR A 259
 None
 0.97A 4w5nA-3zgqA:
undetectable		 4w5nA-3zgqA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Burkholderia
pseudomallei) 		PF00496
(SBP_bac_5) 		4 LEU A 466
ILE A 467
LEU A 353
TYR A 310
 None
 0.94A 4w5nA-3zs6A:
undetectable		 4w5nA-3zs6A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dq7 MEMBRANE PROTEIN
PHI6 P5

(Pseudomonas
virus phi6) 		PF10464
(Peptidase_U40) 		4 LEU A 176
ILE A 173
LEU A 189
GLU A 186
 None
 0.92A 4w5nA-4dq7A:
undetectable		 4w5nA-4dq7A:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eq5 DNA LIGASE

(Thermococcus
sibiricus) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		4 LEU A  56
ILE A  57
LEU A  17
TYR A  14
 None
 0.84A 4w5nA-4eq5A:
undetectable		 4w5nA-4eq5A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hz4 GLUTATHIONE-S-TRANSF
ERASE

(Actinobacillus
pleuropneumoniae) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 LEU A   6
ILE A   4
LEU A  21
GLU A  22
 None
 0.91A 4w5nA-4hz4A:
undetectable		 4w5nA-4hz4A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i0x ESAT-6-LIKE PROTEIN
MAB_3112
ESAT-6-LIKE PROTEIN
MAB_3113

(Mycobacteroides
abscessus;
Mycobacteroides
abscessus) 		PF06013
(WXG100)
PF06013
(WXG100) 		4 LEU A  62
ILE A  65
LEU B  37
GLU B  38
 None
 0.96A 4w5nA-4i0xA:
undetectable		 4w5nA-4i0xA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ieg RNA-DEPENDENT RNA
POLYMERASE P2

(Pseudomonas
phage phi12) 		no annotation 4 LEU A 380
ILE A 377
LEU A 222
TYR A 221
 None
 0.96A 4w5nA-4iegA:
1.3		 4w5nA-4iegA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kbx UNCHARACTERIZED
PROTEIN YHFX

(Escherichia
coli) 		PF01168
(Ala_racemase_N) 		4 LEU A 259
ILE A  38
LEU A  73
TYR A  78
 None
 0.86A 4w5nA-4kbxA:
undetectable		 4w5nA-4kbxA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kh7 GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN

(Salmonella
enterica) 		PF02798
(GST_N)
PF13410
(GST_C_2) 		4 LEU A   4
ILE A   2
LEU A  20
GLU A  21
 None
 0.94A 4w5nA-4kh7A:
undetectable		 4w5nA-4kh7A:
13.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4krf PROTEIN ARGONAUTE-1

(Homo sapiens) 		PF02170
(PAZ)
PF02171
(Piwi)
PF08699
(ArgoL1)
PF16486
(ArgoN)
PF16487
(ArgoMid)
PF16488
(ArgoL2) 		4 LEU A 648
ILE A 649
LEU A 692
TYR A 696
 None
 0.40A 4w5nA-4krfA:
59.7		 4w5nA-4krfA:
82.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]

(Synechocystis
sp. PCC 6803) 		PF02347
(GDC-P) 		4 LEU A 279
ILE A 251
LEU A 263
TYR A 237
 None
 0.97A 4w5nA-4lglA:
3.5		 4w5nA-4lglA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m5p NADPH DEHYDROGENASE

(Scheffersomyces
stipitis) 		PF00724
(Oxidored_FMN) 		4 LEU A 222
ILE A 221
LEU A 266
TYR A 265
 None
 0.92A 4w5nA-4m5pA:
undetectable		 4w5nA-4m5pA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nky STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE

(Homo sapiens) 		PF00067
(p450) 		4 LEU A 293
ILE A 292
LEU A 247
GLU A 248
 None
 0.71A 4w5nA-4nkyA:
undetectable		 4w5nA-4nkyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pe3 TRAP DICARBOXYLATE
TRANSPORTER-DCTP
SUBUNIT

(Rhodobacter
sphaeroides) 		PF03480
(DctP) 		4 ILE A 127
LYS A 346
LEU A 156
GLU A 155
 None
 0.90A 4w5nA-4pe3A:
undetectable		 4w5nA-4pe3A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q9z HUMAN PROTEIN KINASE
C THETA

(Homo sapiens) 		PF00069
(Pkinase)
PF00433
(Pkinase_C) 		4 LEU A 507
ILE A 510
LEU A 568
TYR A 545
 None
 0.98A 4w5nA-4q9zA:
undetectable		 4w5nA-4q9zA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qqf MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM50

(Saccharomyces
cerevisiae) 		no annotation 4 LEU D 327
ILE D 324
LEU D 228
TYR D 232
 None
 0.89A 4w5nA-4qqfD:
undetectable		 4w5nA-4qqfD:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r0i SUPPRESSOR OF
TUMORIGENICITY 14
PROTEIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 LEU A 155
ILE A 154
LYS A 157
GLU A  26
 None
 0.94A 4w5nA-4r0iA:
undetectable		 4w5nA-4r0iA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r8z CYCLIC DI-GMP
PHOSPHODIESTERASE

(Pseudomonas
aeruginosa) 		PF13487
(HD_5) 		4 LEU A 333
ILE A 334
LEU A 315
GLU A 314
 None
 0.65A 4w5nA-4r8zA:
undetectable		 4w5nA-4r8zA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tnb G PROTEIN-COUPLED
RECEPTOR KINASE 5

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		4 LEU A  77
ILE A  81
LEU A 153
TYR A 152
 None
 0.87A 4w5nA-4tnbA:
undetectable		 4w5nA-4tnbA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tv7 HTH-TYPE
TRANSCRIPTIONAL
REGULATORY PROTEIN
GABR

(Bacillus
subtilis) 		PF00155
(Aminotran_1_2)
PF00392
(GntR) 		4 LEU A  24
ILE A  28
LEU A  63
TYR A  60
 None
 0.75A 4w5nA-4tv7A:
2.7		 4w5nA-4tv7A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wsb POLYMERASE PB2

(Influenza A
virus) 		PF00604
(Flu_PB2) 		4 ILE C 163
LYS C 189
LEU C 211
GLU C 210
 None
 0.82A 4w5nA-4wsbC:
undetectable		 4w5nA-4wsbC:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xr7 PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN3

(Saccharomyces
cerevisiae) 		no annotation 4 LEU L 486
ILE L 490
LEU L 402
TYR L 405
 None
 0.98A 4w5nA-4xr7L:
undetectable		 4w5nA-4xr7L:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yhj G PROTEIN-COUPLED
RECEPTOR KINASE 4

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		4 LEU A  77
ILE A  81
LEU A 154
TYR A 153
 None
 0.80A 4w5nA-4yhjA:
undetectable		 4w5nA-4yhjA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ypl LON PROTEASE

(Meiothermus
taiwanensis) 		PF00004
(AAA)
PF05362
(Lon_C) 		5 LEU A 293
ILE A 253
LEU A 290
GLU A 269
TYR A 289
 None
 1.43A 4w5nA-4yplA:
undetectable		 4w5nA-4yplA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ztc AMINOTRANSFERASE
HOMOLOG

(Campylobacter
jejuni) 		PF01041
(DegT_DnrJ_EryC1) 		4 LEU A 160
ILE A 185
LEU A 245
GLU A 246
 None
 0.92A 4w5nA-4ztcA:
undetectable		 4w5nA-4ztcA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a1q AF1502

(Archaeoglobus
fulgidus) 		no annotation 4 ILE A   2
LYS A  41
LEU A  64
GLU A  65
 None
 0.97A 4w5nA-5a1qA:
undetectable		 4w5nA-5a1qA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE

(Thymus vulgaris) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 LEU A 115
ILE A 112
LEU A  99
GLU A 127
 LEU  A 115 ( 0.6A)
ILE  A 112 ( 0.7A)
LEU  A  99 ( 0.6A)
GLU  A 127 ( 0.6A)
 0.85A 4w5nA-5c05A:
undetectable		 4w5nA-5c05A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dpd PROTEIN LYSINE
METHYLTRANSFERASE 1

(Rickettsia
prowazekii) 		PF10119
(MethyTransf_Reg)
PF13847
(Methyltransf_31) 		4 LEU A 508
ILE A 507
LEU A 535
GLU A 536
 None
 0.82A 4w5nA-5dpdA:
undetectable		 4w5nA-5dpdA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5elx ATP-DEPENDENT RNA
HELICASE DBP5

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 LEU A 360
ILE A 359
LEU A 364
GLU A 368
 None
 0.78A 4w5nA-5elxA:
undetectable		 4w5nA-5elxA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f8z PLASMA KALLIKREIN
LIGHT CHAIN

(Homo sapiens) 		PF00089
(Trypsin) 		4 LEU A 155
ILE A 154
LYS A 157
GLU A  26
 SO4  A 302 (-4.7A)
None
SO4  A 304 (-3.7A)
SO4  A 304 (-3.6A)
 0.64A 4w5nA-5f8zA:
undetectable		 4w5nA-5f8zA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gvt PLASMA KALLIKREIN

(Mus musculus) 		no annotation 4 LEU A 155
ILE A 154
LYS A 157
GLU A  26
 None
 0.95A 4w5nA-5gvtA:
undetectable		 4w5nA-5gvtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hs8 HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YODB

(Bacillus
subtilis) 		PF01638
(HxlR) 		4 ILE A  24
LYS A  18
LEU A  57
GLU A  56
 None
 0.85A 4w5nA-5hs8A:
undetectable		 4w5nA-5hs8A:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hsi PUTATIVE
DECARBOXYLASE

(Lactobacillus
brevis) 		PF00282
(Pyridoxal_deC) 		4 LEU A 104
LEU A 466
GLU A 467
TYR A 463
 None
 0.88A 4w5nA-5hsiA:
undetectable		 4w5nA-5hsiA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i39 L-AMINO ACID
DEAMINASE

(Proteus
vulgaris) 		PF01266
(DAO) 		4 LEU A 403
ILE A 283
LEU A 388
GLU A 389
 None
None
EDO  A 506 (-4.1A)
EDO  A 506 (-3.6A)
 0.97A 4w5nA-5i39A:
undetectable		 4w5nA-5i39A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5im6 DESIGNED
SELF-ASSEMBLING
ICOSAHEDRAL CAGE
I32-28 TRIMERIC
SUBUNIT

(Burkholderia
thailandensis) 		PF01923
(Cob_adeno_trans) 		4 LEU A 138
ILE A 135
LEU A  76
GLU A  75
 None
 0.96A 4w5nA-5im6A:
undetectable		 4w5nA-5im6A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5isv RIBOSOMAL-PROTEIN-AL
ANINE
ACETYLTRANSFERASE

(Escherichia
coli) 		PF00583
(Acetyltransf_1) 		4 LEU A  85
ILE A  89
LEU A 118
TYR A 115
 None
 0.96A 4w5nA-5isvA:
undetectable		 4w5nA-5isvA:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kdi PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY A MEMBER 8

(Homo sapiens) 		no annotation 4 LEU A 412
LYS A 416
LEU A 501
GLU A 498
 None
 0.97A 4w5nA-5kdiA:
undetectable		 4w5nA-5kdiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m59 PRE-MRNA SPLICING
HELICASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		4 LEU A 667
ILE A 665
LEU A 676
GLU A 677
 None
 0.88A 4w5nA-5m59A:
undetectable		 4w5nA-5m59A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m6p TYROCIDINE SYNTHASE
2

(Brevibacillus
parabrevis) 		no annotation 4 ILE A3453
LYS A3446
LEU A3308
GLU A3307
 None
 0.82A 4w5nA-5m6pA:
undetectable		 4w5nA-5m6pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n9j MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 17

(Schizosaccharomyces
pombe) 		PF10156
(Med17) 		4 LEU W 478
ILE W 480
LEU W 434
TYR W 431
 None
 0.96A 4w5nA-5n9jW:
undetectable		 4w5nA-5n9jW:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nfj MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1

(Homo sapiens) 		no annotation 4 LEU A 360
ILE A 357
LYS A 364
LEU A 205
 None
 0.95A 4w5nA-5nfjA:
undetectable		 4w5nA-5nfjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o84 GLUTATHIONE
S-TRANSFERASE U23

(Arabidopsis
thaliana) 		no annotation 4 LEU A   7
ILE A   5
LEU A  23
GLU A  24
 None
 0.91A 4w5nA-5o84A:
undetectable		 4w5nA-5o84A:
12.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5vm9 PROTEIN ARGONAUTE-3

(Homo sapiens) 		no annotation 6 LEU A 651
ILE A 652
LYS A 661
LEU A 695
GLU A 696
TYR A 699
 None
 0.59A 4w5nA-5vm9A:
56.5		 4w5nA-5vm9A:
79.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wea PROTEIN ARGONAUTE-2

(Homo sapiens) 		no annotation 5 LEU A 650
ILE A 651
LEU A 694
GLU A 695
TYR A 698
 IPH  A 901 (-4.7A)
IPH  A 901 ( 4.7A)
IPH  A 901 (-3.9A)
IPH  A 901 (-3.6A)
IPH  A 901 ( 4.9A)
 0.67A 4w5nA-5weaA:
60.4		 4w5nA-5weaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wea PROTEIN ARGONAUTE-2

(Homo sapiens) 		no annotation 5 LEU A 650
LYS A 660
LEU A 694
GLU A 695
TYR A 698
 IPH  A 901 (-4.7A)
None
IPH  A 901 (-3.9A)
IPH  A 901 (-3.6A)
IPH  A 901 ( 4.9A)
 0.76A 4w5nA-5weaA:
60.4		 4w5nA-5weaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x9u THERMOSOME, ALPHA
SUBUNIT

(Carboxydothermus
hydrogenoformans) 		no annotation 4 LEU A 130
ILE A 131
LEU A 397
TYR A 396
 None
 0.86A 4w5nA-5x9uA:
undetectable		 4w5nA-5x9uA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yk7 MAINTENANCE OF
MITOCHONDRIAL
MORPHOLOGY PROTEIN 1

(Zygosaccharomyces
rouxii) 		no annotation 4 LEU A 204
ILE A 203
LEU A 295
TYR A 286
 None
 0.88A 4w5nA-5yk7A:
undetectable		 4w5nA-5yk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bvd LIGHT CHAIN

(Clostridium
botulinum) 		no annotation 4 LEU A 228
ILE A 229
LEU A 107
GLU A 110
 None
 0.88A 4w5nA-6bvdA:
2.2		 4w5nA-6bvdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c9e CYSTEINE DESULFURASE

(Legionella
pneumophila) 		no annotation 4 LEU A 223
ILE A 195
LEU A 207
TYR A 180
 None
 0.95A 4w5nA-6c9eA:
undetectable		 4w5nA-6c9eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dcq ENVELOPE
GLYCOPROTEIN GP160

(Human
immunodeficiency
virus 1) 		no annotation 4 ILE A 323
LEU A 154
GLU A 153
TYR A 177
 None
 0.97A 4w5nA-6dcqA:
undetectable		 4w5nA-6dcqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dft -

(-) 		no annotation 4 LEU A 438
ILE A 439
LEU A  54
TYR A  44
 None
 0.91A 4w5nA-6dftA:
undetectable		 4w5nA-6dftA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fpd PROTEIN AB21

(Agaricus
bisporus) 		no annotation 4 LEU A 138
ILE A 141
LEU A 187
TYR A 190
 None
 0.94A 4w5nA-6fpdA:
undetectable		 4w5nA-6fpdA:
undetectable