SIMILAR PATTERNS OF AMINO ACIDS FOR 4V3V_B_H4BB760_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c4k | PROTEIN (ORNITHINEDECARBOXYLASE) (Lactobacillussp. 30A) |
PF01276(OKR_DC_1)PF03709(OKR_DC_1_N)PF03711(OKR_DC_1_C) | 4 | TRP A 673PHE A 681GLU A 649VAL A 667 | None | 1.29A | 4v3vA-1c4kA:0.04v3vB-1c4kA:0.0 | 4v3vA-1c4kA:19.074v3vB-1c4kA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cyo | CYTOCHROME B5 (Bos taurus) |
PF00173(Cyt-b5) | 4 | PHE A 58GLU A 56ARG A 68VAL A 61 | HEM A 201 (-4.8A)NoneNoneNone | 1.31A | 4v3vA-1cyoA:0.04v3vB-1cyoA:0.0 | 4v3vA-1cyoA:12.054v3vB-1cyoA:12.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fhu | O-SUCCINYLBENZOATESYNTHASE (Escherichiacoli) |
PF13378(MR_MLE_C) | 4 | TRP A 66GLU A 76ARG A 2VAL A 87 | None | 1.47A | 4v3vA-1fhuA:0.04v3vB-1fhuA:0.0 | 4v3vA-1fhuA:25.234v3vB-1fhuA:25.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1flg | PROTEIN(QUINOPROTEINETHANOLDEHYDROGENASE) (Pseudomonasaeruginosa) |
PF01011(PQQ)PF13360(PQQ_2) | 4 | PHE A 501GLU A 519VAL A 41TRP A 521 | None | 1.23A | 4v3vA-1flgA:0.04v3vB-1flgA:0.0 | 4v3vA-1flgA:19.674v3vB-1flgA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h2t | 80 KDA NUCLEAR CAPBINDING PROTEIN (Homo sapiens) |
PF02854(MIF4G)PF09088(MIF4G_like)PF09090(MIF4G_like_2) | 4 | PHE C 360GLU C 353MET C 291VAL C 216 | None | 1.35A | 4v3vA-1h2tC:0.04v3vB-1h2tC:0.0 | 4v3vA-1h2tC:19.484v3vB-1h2tC:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kex | NEUROPILIN-1 (Homo sapiens) |
PF00754(F5_F8_type_C) | 4 | TRP A 97PHE A 131GLU A 95ARG A 130 | None | 1.46A | 4v3vA-1kexA:undetectable4v3vB-1kexA:0.0 | 4v3vA-1kexA:16.834v3vB-1kexA:16.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kh2 | ARGININOSUCCINATESYNTHETASE (Thermusthermophilus) |
PF00764(Arginosuc_synth) | 4 | PHE A 220GLU A 222ARG A 282VAL A 226 | None | 1.32A | 4v3vA-1kh2A:0.64v3vB-1kh2A:0.0 | 4v3vA-1kh2A:22.654v3vB-1kh2A:22.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lzx | NITRIC-OXIDESYNTHASE (Rattusnorvegicus) |
PF02898(NO_synthase) | 4 | MET A 336ARG A 596VAL A 677TRP A 678 | H4B A 760 ( 3.8A)H4B A 760 (-3.5A)H4B A 760 (-4.6A)H4B A 760 ( 3.6A) | 0.29A | 4v3vA-1lzxA:63.14v3vB-1lzxA:62.1 | 4v3vA-1lzxA:100.004v3vB-1lzxA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m59 | CYTOCHROME B5 (Bos taurus) |
PF00173(Cyt-b5) | 4 | PHE A 58GLU A 56ARG A 68VAL A 61 | HEM A 201 (-4.7A)NoneNoneNone | 1.49A | 4v3vA-1m59A:0.04v3vB-1m59A:0.0 | 4v3vA-1m59A:10.604v3vB-1m59A:10.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mhz | METHANEMONOOXYGENASEHYDROXYLASE (Methylosinustrichosporium) |
PF02332(Phenol_Hydrox) | 4 | PHE D 35GLU D 132VAL D 28TRP D 31 | None | 1.39A | 4v3vA-1mhzD:undetectable4v3vB-1mhzD:undetectable | 4v3vA-1mhzD:20.854v3vB-1mhzD:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mzb | FERRIC UPTAKEREGULATION PROTEIN (Pseudomonasaeruginosa) |
PF01475(FUR) | 4 | PHE A 79GLU A 36ARG A 69VAL A 54 | None | 1.05A | 4v3vA-1mzbA:undetectable4v3vB-1mzbA:undetectable | 4v3vA-1mzbA:16.594v3vB-1mzbA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pdu | NUCLEAR HORMONERECEPTOR HR38 (Drosophilamelanogaster) |
PF00104(Hormone_recep) | 4 | TRP A 435PHE A 432MET A 440VAL A 401 | None | 0.85A | 4v3vA-1pduA:undetectable4v3vB-1pduA:undetectable | 4v3vA-1pduA:21.054v3vB-1pduA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t1j | HYPOTHETICAL PROTEIN (Pseudomonasaeruginosa) |
PF09152(DUF1937) | 4 | TRP A 110PHE A 117ARG A 2VAL A 28 | None | 1.44A | 4v3vA-1t1jA:undetectable4v3vB-1t1jA:undetectable | 4v3vA-1t1jA:16.384v3vB-1t1jA:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tki | TITIN (Homo sapiens) |
PF00069(Pkinase) | 4 | TRP A 277PHE A 254GLU A 250VAL A 122 | None | 1.48A | 4v3vA-1tkiA:undetectable4v3vB-1tkiA:undetectable | 4v3vA-1tkiA:20.234v3vB-1tkiA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vmk | PURINE NUCLEOSIDEPHOSPHORYLASE (Thermotogamaritima) |
PF01048(PNP_UDP_1) | 4 | TRP A 162PHE A 265GLU A 161VAL A 221 | None | 1.45A | 4v3vA-1vmkA:undetectable4v3vB-1vmkA:undetectable | 4v3vA-1vmkA:21.484v3vB-1vmkA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wf0 | TAR DNA-BINDINGPROTEIN-43 (Homo sapiens) |
PF00076(RRM_1) | 4 | PHE A 26GLU A 21MET A 17VAL A 35 | None | 1.19A | 4v3vA-1wf0A:undetectable4v3vB-1wf0A:undetectable | 4v3vA-1wf0A:11.854v3vB-1wf0A:11.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wql | ETHYLBENZENEDIOXYGENASE SMALLSUBUNIT (Pseudomonasfluorescens) |
PF00866(Ring_hydroxyl_B) | 4 | PHE B 163GLU B 26ARG B 156VAL B 128 | None | 1.18A | 4v3vA-1wqlB:undetectable4v3vB-1wqlB:undetectable | 4v3vA-1wqlB:19.794v3vB-1wqlB:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b39 | C3 (Bos taurus) |
PF00207(A2M)PF01759(NTR)PF01821(ANATO)PF01835(A2M_N)PF07677(A2M_recep)PF07678(A2M_comp)PF07703(A2M_N_2)PF10569(Thiol-ester_cl) | 4 | PHE A 722GLU A 693ARG A 708VAL A1424 | None | 1.03A | 4v3vA-2b39A:undetectable4v3vB-2b39A:undetectable | 4v3vA-2b39A:13.584v3vB-2b39A:13.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fja | ADENYLYLSULFATEREDUCTASE, SUBUNIT A (Archaeoglobusfulgidus) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 4 | GLU A 555ARG A 586VAL A 578TRP A 579 | None | 1.28A | 4v3vA-2fjaA:0.74v3vB-2fjaA:undetectable | 4v3vA-2fjaA:22.294v3vB-2fjaA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fja | ADENYLYLSULFATEREDUCTASE, SUBUNIT AADENYLYLSULFATEREDUCTASE, SUBUNIT B (Archaeoglobusfulgidus) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C)PF12139(APS-reductase_C)PF13187(Fer4_9) | 4 | TRP B 788GLU A 360ARG A 62VAL A 367 | None | 1.32A | 4v3vA-2fjaB:undetectable4v3vB-2fjaB:undetectable | 4v3vA-2fjaB:18.254v3vB-2fjaB:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i9u | CYTOSINE/GUANINEDEAMINASE RELATEDPROTEIN (Clostridiumacetobutylicum) |
PF01979(Amidohydro_1) | 4 | PHE A 99GLU A 101ARG A 202TRP A 93 | NoneNoneGUN A 503 (-3.7A)None | 1.36A | 4v3vA-2i9uA:undetectable4v3vB-2i9uA:undetectable | 4v3vA-2i9uA:20.974v3vB-2i9uA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r0q | PUTATIVE TRANSPOSONTN552 DNA-INVERTASEBIN3 (Staphylococcusaureus) |
PF00239(Resolvase)PF02796(HTH_7) | 4 | PHE C 31GLU C 28MET C 1VAL C 53 | None | 1.48A | 4v3vA-2r0qC:undetectable4v3vB-2r0qC:undetectable | 4v3vA-2r0qC:17.804v3vB-2r0qC:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rik | TITIN (Oryctolaguscuniculus) |
PF07679(I-set) | 4 | PHE A 97GLU A 116VAL A 127TRP A 129 | None | 1.38A | 4v3vA-2rikA:undetectable4v3vB-2rikA:undetectable | 4v3vA-2rikA:22.524v3vB-2rikA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vda | TRANSLOCASE SUBUNITSECA (Escherichiacoli) |
PF01043(SecA_PP_bind)PF07516(SecA_SW)PF07517(SecA_DEAD) | 4 | GLU A 34MET A 31ARG A 53VAL A 70 | None | 1.44A | 4v3vA-2vdaA:undetectable4v3vB-2vdaA:undetectable | 4v3vA-2vdaA:20.584v3vB-2vdaA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w4o | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE TYPE IV (Homo sapiens) |
PF00069(Pkinase) | 4 | TRP A 266PHE A 261ARG A 278VAL A 269 | None | 1.43A | 4v3vA-2w4oA:undetectable4v3vB-2w4oA:undetectable | 4v3vA-2w4oA:20.264v3vB-2w4oA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xhy | 6-PHOSPHO-BETA-GLUCOSIDASE BGLA (Escherichiacoli) |
PF00232(Glyco_hydro_1) | 4 | PHE A 98GLU A 108ARG A 159VAL A 164 | None | 1.46A | 4v3vA-2xhyA:0.34v3vB-2xhyA:undetectable | 4v3vA-2xhyA:20.634v3vB-2xhyA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xvg | ALPHA XYLOSIDASE (Cellvibriojaponicus) |
PF01055(Glyco_hydro_31)PF16338(DUF4968)PF17137(DUF5110) | 4 | PHE A 698GLU A 722ARG A 697VAL A 717 | None | 1.30A | 4v3vA-2xvgA:undetectable4v3vB-2xvgA:undetectable | 4v3vA-2xvgA:19.684v3vB-2xvgA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ywb | GMP SYNTHASE[GLUTAMINE-HYDROLYZING] (Thermusthermophilus) |
PF00117(GATase)PF00958(GMP_synt_C) | 4 | PHE A 309GLU A 305ARG A 211VAL A 239 | None | 1.30A | 4v3vA-2ywbA:undetectable4v3vB-2ywbA:undetectable | 4v3vA-2ywbA:21.544v3vB-2ywbA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z11 | RIBOSOMAL-PROTEIN-ALANINEACETYLTRANSFERASE (Thermusthermophilus) |
PF13302(Acetyltransf_3) | 4 | TRP A 66PHE A 4GLU A 6VAL A 64 | None | 1.40A | 4v3vA-2z11A:undetectable4v3vB-2z11A:undetectable | 4v3vA-2z11A:17.584v3vB-2z11A:17.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zf8 | COMPONENT OFSODIUM-DRIVEN POLARFLAGELLAR MOTOR (Vibrioalginolyticus) |
PF00691(OmpA) | 4 | TRP A 15PHE A 137GLU A 16MET A 17 | None | 1.28A | 4v3vA-2zf8A:undetectable4v3vB-2zf8A:undetectable | 4v3vA-2zf8A:21.354v3vB-2zf8A:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ahi | XYLULOSE5-PHOSPHATE/FRUCTOSE6-PHOSPHATEPHOSPHOKETOLASE (Bifidobacteriumbreve) |
PF03894(XFP)PF09363(XFP_C)PF09364(XFP_N) | 4 | TRP A 498GLU A 487MET A 511VAL A 505 | None | 1.26A | 4v3vA-3ahiA:undetectable4v3vB-3ahiA:undetectable | 4v3vA-3ahiA:18.654v3vB-3ahiA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ai7 | XYLULOSE-5-PHOSPHATE/FRUCTOSE-6-PHOSPHATE PHOSPHOKETOLASE (Bifidobacteriumlongum) |
PF03894(XFP)PF09363(XFP_C)PF09364(XFP_N) | 4 | TRP A 498GLU A 487MET A 511VAL A 505 | None | 1.24A | 4v3vA-3ai7A:undetectable4v3vB-3ai7A:undetectable | 4v3vA-3ai7A:19.144v3vB-3ai7A:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b7f | GLYCOSYL HYDROLASE,BNR REPEAT (Cupriaviduspinatubonensis) |
no annotation | 4 | TRP A 374GLU A 372VAL A 314TRP A 293 | NoneEDO A 404 ( 3.8A)NoneNone | 1.41A | 4v3vA-3b7fA:undetectable4v3vB-3b7fA:undetectable | 4v3vA-3b7fA:20.874v3vB-3b7fA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bxz | PREPROTEINTRANSLOCASE SUBUNITSECA (Escherichiacoli) |
PF07517(SecA_DEAD) | 4 | GLU A 34MET A 31ARG A 53VAL A 70 | None | 1.48A | 4v3vA-3bxzA:undetectable4v3vB-3bxzA:undetectable | 4v3vA-3bxzA:20.854v3vB-3bxzA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d2w | TAR DNA-BINDINGPROTEIN 43 (Mus musculus) |
PF00076(RRM_1) | 4 | PHE A 211GLU A 206MET A 202VAL A 220 | None | 0.98A | 4v3vA-3d2wA:undetectable4v3vB-3d2wA:undetectable | 4v3vA-3d2wA:12.224v3vB-3d2wA:12.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ddl | XANTHORHODOPSIN (Salinibacterruber) |
PF01036(Bac_rhodopsin) | 4 | TRP A 70PHE A 88GLU A 71VAL A 16 | None | 1.45A | 4v3vA-3ddlA:undetectable4v3vB-3ddlA:undetectable | 4v3vA-3ddlA:20.144v3vB-3ddlA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gs3 | SYMPLEKIN (Drosophilamelanogaster) |
PF11935(DUF3453) | 4 | PHE A 67GLU A 65ARG A 27VAL A 56 | None | 1.49A | 4v3vA-3gs3A:undetectable4v3vB-3gs3A:undetectable | 4v3vA-3gs3A:20.284v3vB-3gs3A:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gyx | ADENYLYLSULFATEREDUCTASE (Desulfovibriogigas) |
PF00890(FAD_binding_2)PF12139(APS-reductase_C)PF13187(Fer4_9) | 4 | TRP B 88GLU A 380ARG A 66VAL A 387 | None | 1.25A | 4v3vA-3gyxB:undetectable4v3vB-3gyxB:undetectable | 4v3vA-3gyxB:16.674v3vB-3gyxB:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hzp | NTF2-LIKE PROTEIN OFUNKNOWN FUNCTION (Prochlorococcusmarinus) |
PF12707(DUF3804) | 4 | PHE A 34MET A 20ARG A 118TRP A 51 | 1PE A 131 (-4.5A)1PE A 131 ( 3.8A)1PE A 131 (-3.7A)None | 1.38A | 4v3vA-3hzpA:undetectable4v3vB-3hzpA:undetectable | 4v3vA-3hzpA:14.184v3vB-3hzpA:14.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ma6 | CALMODULIN-DOMAINPROTEIN KINASE 1 (Toxoplasmagondii) |
PF00069(Pkinase) | 4 | TRP A 257PHE A 252ARG A 269VAL A 260 | None | 1.43A | 4v3vA-3ma6A:undetectable4v3vB-3ma6A:undetectable | 4v3vA-3ma6A:21.554v3vB-3ma6A:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ner | CYTOCHROME B5 TYPE B (Homo sapiens) |
PF00173(Cyt-b5) | 4 | PHE A 58GLU A 56ARG A 68VAL A 61 | HEM A 201 (-4.7A)NoneNoneHEM A 201 (-4.5A) | 1.48A | 4v3vA-3nerA:undetectable4v3vB-3nerA:undetectable | 4v3vA-3nerA:14.934v3vB-3nerA:14.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3owc | PROBABLEACETYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00583(Acetyltransf_1) | 4 | PHE A 121GLU A 119ARG A 175VAL A 92 | None | 1.23A | 4v3vA-3owcA:undetectable4v3vB-3owcA:undetectable | 4v3vA-3owcA:16.474v3vB-3owcA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q63 | MLL2253 PROTEIN (Mesorhizobiumjaponicum) |
PF08327(AHSA1) | 4 | PHE A 113GLU A 109MET A 108TRP A 128 | None | 1.27A | 4v3vA-3q63A:undetectable4v3vB-3q63A:undetectable | 4v3vA-3q63A:13.714v3vB-3q63A:13.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rjy | ENDOGLUCANASEFNCEL5A (Fervidobacteriumnodosum) |
PF00150(Cellulase) | 4 | TRP A 146PHE A 162GLU A 187VAL A 149 | None | 1.27A | 4v3vA-3rjyA:0.84v3vB-3rjyA:undetectable | 4v3vA-3rjyA:21.274v3vB-3rjyA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ti8 | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | PHE A 305GLU A 265VAL A 240TRP A 239 | None | 1.36A | 4v3vA-3ti8A:undetectable4v3vB-3ti8A:undetectable | 4v3vA-3ti8A:22.644v3vB-3ti8A:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqu | NON-CANONICAL PURINENTP PYROPHOSPHATASE (Coxiellaburnetii) |
PF01725(Ham1p_like) | 4 | TRP A 140PHE A 118GLU A 141VAL A 162 | None | 1.27A | 4v3vA-3tquA:undetectable4v3vB-3tquA:undetectable | 4v3vA-3tquA:19.054v3vB-3tquA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uxm | THYMIDYLATE KINASE (Pseudomonasaeruginosa) |
PF02223(Thymidylate_kin) | 4 | PHE A 162GLU A 156ARG A 109VAL A 166 | None MG A 213 (-3.2A)NoneNone | 1.29A | 4v3vA-3uxmA:undetectable4v3vB-3uxmA:undetectable | 4v3vA-3uxmA:20.294v3vB-3uxmA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bs2 | TAR DNA-BINDINGPROTEIN 43 (Homo sapiens) |
PF00076(RRM_1) | 4 | PHE A 211GLU A 206MET A 202VAL A 220 | None | 1.06A | 4v3vA-4bs2A:undetectable4v3vB-4bs2A:undetectable | 4v3vA-4bs2A:15.874v3vB-4bs2A:15.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d8o | ANKYRIN-2 (Homo sapiens) |
PF00531(Death)PF00791(ZU5) | 4 | PHE A1118GLU A1032ARG A1065VAL A1046 | None | 1.35A | 4v3vA-4d8oA:undetectable4v3vB-4d8oA:undetectable | 4v3vA-4d8oA:19.444v3vB-4d8oA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g76 | PHOSPHODIESTERASE (Pseudomonasaeruginosa) |
PF14859(Colicin_M) | 4 | TRP A 62PHE A 85MET A 258VAL A 265 | None | 1.30A | 4v3vA-4g76A:undetectable4v3vB-4g76A:undetectable | 4v3vA-4g76A:19.864v3vB-4g76A:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l37 | ARYLPHORIN (Bombyx mori) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 4 | PHE B 327GLU B 424VAL B 351TRP B 355 | None | 1.03A | 4v3vA-4l37B:undetectable4v3vB-4l37B:undetectable | 4v3vA-4l37B:20.694v3vB-4l37B:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mh1 | SORBOSEDEHYDROGENASE (Ketogulonicigeniumvulgare) |
PF13360(PQQ_2) | 4 | TRP A 218PHE A 286ARG A 385TRP A 387 | None | 1.41A | 4v3vA-4mh1A:undetectable4v3vB-4mh1A:undetectable | 4v3vA-4mh1A:21.164v3vB-4mh1A:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mln | PREDICTED HDPHOSPHOHYDROLASEPHNZ (unculturedbacteriumHF130_AEPn_1) |
PF01966(HD) | 4 | PHE A 93GLU A 183MET A 180VAL A 9 | None | 1.24A | 4v3vA-4mlnA:undetectable4v3vB-4mlnA:undetectable | 4v3vA-4mlnA:16.554v3vB-4mlnA:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n6w | PREDICTED HDPHOSPHOHYDROLASEPHNZ (unculturedbacteriumHF130_AEPn_1) |
PF01966(HD) | 4 | PHE A 93GLU A 183MET A 180VAL A 9 | None | 1.31A | 4v3vA-4n6wA:undetectable4v3vB-4n6wA:undetectable | 4v3vA-4n6wA:19.624v3vB-4n6wA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pne | METHYLTRANSFERASE-LIKE PROTEIN (Saccharopolysporaspinosa) |
PF08241(Methyltransf_11) | 4 | PHE A 141GLU A 162ARG A 75VAL A 79 | None | 1.36A | 4v3vA-4pneA:undetectable4v3vB-4pneA:undetectable | 4v3vA-4pneA:21.364v3vB-4pneA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xj6 | VC0179-LIKE PROTEIN (Escherichiacoli) |
no annotation | 4 | PHE A 264GLU A 266ARG A 276VAL A 305 | None | 1.15A | 4v3vA-4xj6A:1.64v3vB-4xj6A:undetectable | 4v3vA-4xj6A:21.064v3vB-4xj6A:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xj6 | VC0179-LIKE PROTEIN (Escherichiacoli) |
no annotation | 4 | TRP A 263PHE A 264GLU A 266VAL A 305 | None | 1.06A | 4v3vA-4xj6A:1.64v3vB-4xj6A:undetectable | 4v3vA-4xj6A:21.064v3vB-4xj6A:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ylr | TUBULINPOLYGLUTAMYLASETTLL7 (Homo sapiens) |
PF03133(TTL) | 4 | PHE A 277GLU A 279VAL A 288TRP A 292 | None | 1.44A | 4v3vA-4ylrA:undetectable4v3vB-4ylrA:undetectable | 4v3vA-4ylrA:22.814v3vB-4ylrA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zva | DIGUANYLATE CYCLASEDOSC (Escherichiacoli) |
PF11563(Protoglobin) | 4 | TRP A 12GLU A 11MET A 8VAL A 84 | None | 1.37A | 4v3vA-4zvaA:1.44v3vB-4zvaA:undetectable | 4v3vA-4zvaA:18.864v3vB-4zvaA:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bs1 | CRRBCX-IIA (Chlamydomonasreinhardtii) |
PF02341(RcbX) | 4 | TRP A 104GLU A 103ARG A 123VAL A 108 | TRP A 104 ( 0.5A)GLU A 103 ( 0.6A)ARG A 123 ( 0.6A)VAL A 108 ( 0.6A) | 1.31A | 4v3vA-5bs1A:undetectable4v3vB-5bs1A:undetectable | 4v3vA-5bs1A:14.454v3vB-5bs1A:14.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5by3 | BTGH115A (Bacteroidesthetaiotaomicron) |
PF15979(Glyco_hydro_115) | 4 | TRP A 732GLU A 731ARG A 505VAL A 736 | None | 1.39A | 4v3vA-5by3A:undetectable4v3vB-5by3A:undetectable | 4v3vA-5by3A:19.824v3vB-5by3A:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c6g | AGR133CPSISTER CHROMATIDCOHESION PROTEIN 2 (Eremotheciumgossypii) |
PF10345(Cohesin_load)no annotation | 4 | TRP A 401PHE A 397GLU A 402VAL B 28 | None | 1.48A | 4v3vA-5c6gA:3.54v3vB-5c6gA:undetectable | 4v3vA-5c6gA:21.864v3vB-5c6gA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8t | 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACIDOXIDASE (Homo sapiens) |
PF00264(Tyrosinase) | 4 | TRP A 414PHE A 411GLU A 413ARG A 225 | None | 1.07A | 4v3vA-5m8tA:0.04v3vB-5m8tA:undetectable | 4v3vA-5m8tA:20.004v3vB-5m8tA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wq3 | CYTOKININ RIBOSIDE5'-MONOPHOSPHATEPHOSPHORIBOHYDROLASE (Corynebacteriumglutamicum) |
PF03641(Lysine_decarbox) | 4 | PHE A 159MET A 112ARG A 155VAL A 104 | None | 1.44A | 4v3vA-5wq3A:undetectable4v3vB-5wq3A:undetectable | 4v3vA-5wq3A:24.234v3vB-5wq3A:24.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x89 | ENDA-LIKEPROTEIN,TRNA-SPLICING ENDONUCLEASE (Methanopyruskandleri) |
no annotation | 4 | PHE A 258GLU A 253MET A 249VAL A 231 | None | 1.02A | 4v3vA-5x89A:undetectable4v3vB-5x89A:undetectable | 4v3vA-5x89A:12.704v3vB-5x89A:12.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwd | VH CHAIN OF 059-152VL CHAIN OF 059-152 (Homo sapiens) |
no annotation | 4 | TRP H 49MET H 105VAL D 98TRP D 91 | None | 1.14A | 4v3vA-5xwdH:undetectable4v3vB-5xwdH:undetectable | 4v3vA-5xwdH:9.594v3vB-5xwdH:9.59 |