SIMILAR PATTERNS OF AMINO ACIDS FOR 4UCK_A_SAMA2409_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13pk 3-PHOSPHOGLYCERATE
KINASE

(Trypanosoma
brucei) 		PF00162
(PGK) 		3 SER A 380
ASP A 165
ASP A  37
 None
 0.74A 4uckA-13pkA:
2.1		 4uckA-13pkA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ap8 TRANSLATION
INITIATION FACTOR
EIF4E

(Saccharomyces
cerevisiae) 		PF01652
(IF4E) 		3 SER A 210
ASP A  99
ASP A 171
 None
 0.81A 4uckA-1ap8A:
undetectable		 4uckA-1ap8A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b04 PROTEIN (DNA LIGASE)

(Geobacillus
stearothermophilus) 		PF01653
(DNA_ligase_aden) 		3 SER A 213
ASP A 143
ASP A 207
 None
 0.79A 4uckA-1b04A:
undetectable		 4uckA-1b04A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b0k PROTEIN (ACONITASE)

(Sus scrofa) 		PF00330
(Aconitase)
PF00694
(Aconitase_C) 		3 SER A 643
ASP A  67
ASP A 185
 FLC  A 756 (-2.8A)
None
None
 0.74A 4uckA-1b0kA:
undetectable		 4uckA-1b0kA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cg2 CARBOXYPEPTIDASE G2

(Pseudomonas sp.
RS-16) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		3 SER A 111
ASP A 206
ASP A 141
 None
None
ZN  A 500 (-2.4A)
 0.82A 4uckA-1cg2A:
undetectable		 4uckA-1cg2A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1clw TAILSPIKE PROTEIN

(Salmonella
virus P22) 		PF09251
(PhageP22-tail) 		3 SER A 521
ASP A 531
ASP A 517
 None
 0.80A 4uckA-1clwA:
undetectable		 4uckA-1clwA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e33 ARYLSULFATASE A

(Homo sapiens) 		PF00884
(Sulfatase)
PF14707
(Sulfatase_C) 		3 SER P 418
ASP P  30
ASP P 407
 None
MG  P 603 (-3.2A)
None
 0.81A 4uckA-1e33P:
undetectable		 4uckA-1e33P:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1flc HAEMAGGLUTININ-ESTER
ASE-FUSION
GLYCOPROTEIN

(Influenza C
virus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		3 SER A 290
ASP A 247
ASP A 257
 None
 0.78A 4uckA-1flcA:
undetectable		 4uckA-1flcA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fnn CELL DIVISION
CONTROL PROTEIN 6

(Pyrobaculum
aerophilum) 		PF09079
(Cdc6_C)
PF13401
(AAA_22) 		3 SER A 366
ASP A 199
ASP A 217
 None
 0.70A 4uckA-1fnnA:
undetectable		 4uckA-1fnnA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gji C-REL PROTO-ONCOGENE
PROTEIN

(Gallus gallus) 		PF00554
(RHD_DNA_bind)
PF16179
(RHD_dimer) 		3 SER A 266
ASP A 234
ASP A 213
 None
 0.74A 4uckA-1gjiA:
undetectable		 4uckA-1gjiA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hr7 MITOCHONDRIAL
PROCESSING PEPTIDASE
ALPHA SUBUNIT

(Saccharomyces
cerevisiae) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		3 SER A  33
ASP A  47
ASP A 391
 None
 0.79A 4uckA-1hr7A:
undetectable		 4uckA-1hr7A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i6q LACTOFERRIN

(Camelus
dromedarius) 		PF00405
(Transferrin) 		3 SER A 122
ASP A 302
ASP A  60
 CO3  A 692 (-4.1A)
None
None
 0.77A 4uckA-1i6qA:
undetectable		 4uckA-1i6qA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j71 ASPARTIC PROTEINASE

(Candida
tropicalis) 		PF00026
(Asp) 		3 SER A 329
ASP A 312
ASP A   2
 None
EOH  A 573 ( 4.5A)
None
 0.77A 4uckA-1j71A:
undetectable		 4uckA-1j71A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcw CERULOPLASMIN

(Homo sapiens) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 SER A 172
ASP A 128
ASP A 165
 None
 0.83A 4uckA-1kcwA:
undetectable		 4uckA-1kcwA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1knl ENDO-1,4-BETA-XYLANA
SE A

(Streptomyces
lividans) 		PF00652
(Ricin_B_lectin) 		3 SER A  13
ASP A  21
ASP A  34
 None
GOL  A 531 (-4.1A)
None
 0.79A 4uckA-1knlA:
undetectable		 4uckA-1knlA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1laj CAPSID PROTEIN

(Tomato aspermy
virus) 		PF00760
(Cucumo_coat) 		3 SER A 119
ASP A  74
ASP A 196
 None
 0.82A 4uckA-1lajA:
undetectable		 4uckA-1lajA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mio NITROGENASE
MOLYBDENUM IRON
PROTEIN (BETA CHAIN)

(Clostridium
pasteurianum) 		PF00148
(Oxidored_nitro) 		3 SER B 366
ASP B 322
ASP B 355
 None
 0.76A 4uckA-1mioB:
undetectable		 4uckA-1mioB:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mpo MALTOPORIN

(Escherichia
coli) 		PF02264
(LamB) 		3 SER A 333
ASP A 237
ASP A 300
 None
 0.80A 4uckA-1mpoA:
undetectable		 4uckA-1mpoA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n7d LOW-DENSITY
LIPOPROTEIN RECEPTOR

(Homo sapiens) 		PF00057
(Ldl_recept_a)
PF00058
(Ldl_recept_b)
PF07645
(EGF_CA)
PF14670
(FXa_inhibition) 		3 SER A 185
ASP A 601
ASP A 200
 None
None
CA  A1003 (-2.6A)
 0.66A 4uckA-1n7dA:
undetectable		 4uckA-1n7dA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n8p CYSTATHIONINE
GAMMA-LYASE

(Saccharomyces
cerevisiae) 		PF01053
(Cys_Met_Meta_PP) 		3 SER A 340
ASP A 274
ASP A 383
 None
 0.51A 4uckA-1n8pA:
undetectable		 4uckA-1n8pA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o94 ELECTRON TRANSFER
FLAVOPROTEIN
BETA-SUBUNIT

(Methylophilus
methylotrophus) 		PF01012
(ETF) 		3 SER C 123
ASP C  70
ASP C  39
 None
None
AMP  C1236 (-2.6A)
 0.74A 4uckA-1o94C:
undetectable		 4uckA-1o94C:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1obb ALPHA-GLUCOSIDASE

(Thermotoga
maritima) 		PF02056
(Glyco_hydro_4)
PF11975
(Glyco_hydro_4C) 		3 SER A 143
ASP A  39
ASP A  72
 None
NAD  A 500 (-2.7A)
None
 0.72A 4uckA-1obbA:
3.0		 4uckA-1obbA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q15 CARA

(Pectobacterium
carotovorum) 		PF00733
(Asn_synthase)
PF09147
(DUF1933) 		3 SER A  58
ASP A 239
ASP A 233
 None
 0.69A 4uckA-1q15A:
undetectable		 4uckA-1q15A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6a GENOME POLYPROTEIN

(Dengue virus) 		PF01728
(FtsJ) 		3 SER A  56
ASP A 131
ASP A 146
 SAH  A 887 ( 2.8A)
SAH  A 887 ( 3.3A)
SAH  A 887 (-3.9A)
 0.70A 4uckA-1r6aA:
9.0		 4uckA-1r6aA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6v SUBTILISIN-LIKE
SERINE PROTEASE

(Fervidobacterium
pennivorans) 		PF00082
(Peptidase_S8) 		3 SER A 202
ASP A 254
ASP A 170
 None
 0.81A 4uckA-1r6vA:
undetectable		 4uckA-1r6vA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rkv HOMOSERINE KINASE

(Pseudomonas
aeruginosa) 		PF12710
(HAD) 		3 SER A 153
ASP A  38
ASP A  91
 MG  A 401 ( 3.9A)
None
PO4  A 320 (-4.6A)
 0.65A 4uckA-1rkvA:
undetectable		 4uckA-1rkvA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ryn PROTEIN CRS2

(Zea mays) 		PF01195
(Pept_tRNA_hydro) 		3 SER A  97
ASP A 163
ASP A  94
 SER  A  97 ( 0.0A)
ASP  A 163 ( 0.6A)
ASP  A  94 ( 0.6A)
 0.78A 4uckA-1rynA:
undetectable		 4uckA-1rynA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ryo SEROTRANSFERRIN

(Homo sapiens) 		PF00405
(Transferrin) 		3 SER A 125
ASP A  47
ASP A  69
 OXL  A 328 ( 4.6A)
None
None
 0.73A 4uckA-1ryoA:
undetectable		 4uckA-1ryoA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tt7 YHFP

(Bacillus
subtilis) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 SER A  91
ASP A 223
ASP A 272
 None
 0.79A 4uckA-1tt7A:
undetectable		 4uckA-1tt7A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1udq RIBONUCLEASE PH

(Aquifex
aeolicus) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C) 		3 SER A 198
ASP A 139
ASP A 157
 None
 0.79A 4uckA-1udqA:
undetectable		 4uckA-1udqA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vko INOSITOL-3-PHOSPHATE
SYNTHASE

(Caenorhabditis
elegans) 		PF01658
(Inos-1-P_synth)
PF07994
(NAD_binding_5) 		3 SER A 367
ASP A 438
ASP A 312
 None
None
NAD  A 601 (-3.7A)
 0.75A 4uckA-1vkoA:
undetectable		 4uckA-1vkoA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wad CYTOCHROME C3

(Desulfovibrio
gigas) 		PF02085
(Cytochrom_CIII) 		3 SER A  64
ASP A  11
ASP A  59
 None
CA  A 116 ( 3.3A)
None
 0.80A 4uckA-1wadA:
undetectable		 4uckA-1wadA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wom SIGMA FACTOR SIGB
REGULATION PROTEIN
RSBQ

(Bacillus
subtilis) 		PF12697
(Abhydrolase_6) 		3 SER A 198
ASP A  64
ASP A  72
 None
 0.81A 4uckA-1womA:
undetectable		 4uckA-1womA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfk FORMIMIDOYLGLUTAMASE

(Vibrio cholerae) 		PF00491
(Arginase) 		3 SER A 176
ASP A 306
ASP A 256
 None
 0.63A 4uckA-1xfkA:
undetectable		 4uckA-1xfkA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yew PARTICULATE METHANE
MONOOXYGENASE, B
SUBUNIT

(Methylococcus
capsulatus) 		PF04744
(Monooxygenase_B) 		3 SER A 412
ASP A 406
ASP A 288
 None
 0.68A 4uckA-1yewA:
undetectable		 4uckA-1yewA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aaj MALONATE
SEMIALDEHYDE
DECARBOXYLASE

(Pseudomonas
pavonaceae) 		PF14552
(Tautomerase_2) 		3 SER A  72
ASP A  21
ASP A  37
 None
 0.60A 4uckA-2aajA:
undetectable		 4uckA-2aajA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bbv PROTEIN (BLACK
BEETLE VIRUS CAPSID
PROTEIN)

(Black beetle
virus) 		PF01829
(Peptidase_A6) 		3 SER A 272
ASP A 295
ASP A 221
 None
None
CA  A 364 (-3.1A)
 0.70A 4uckA-2bbvA:
undetectable		 4uckA-2bbvA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c3o PYRUVATE-FERREDOXIN
OXIDOREDUCTASE

(Desulfovibrio
africanus) 		PF01558
(POR)
PF01855
(POR_N)
PF02775
(TPP_enzyme_C)
PF10371
(EKR)
PF13484
(Fer4_16)
PF17147
(PFOR_II) 		3 SER A 371
ASP A 397
ASP A 652
 None
 0.72A 4uckA-2c3oA:
undetectable		 4uckA-2c3oA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dj2 PROTEIN
DISULFIDE-ISOMERASE
A4

(Mus musculus) 		PF00085
(Thioredoxin) 		3 SER A   2
ASP A  25
ASP A  19
 None
 0.79A 4uckA-2dj2A:
undetectable		 4uckA-2dj2A:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dup VESICULAR
INTEGRAL-MEMBRANE
PROTEIN VIP36

(Canis lupus) 		PF03388
(Lectin_leg-like) 		3 SER A 270
ASP A 205
ASP A 212
 None
 0.61A 4uckA-2dupA:
undetectable		 4uckA-2dupA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e0w GAMMA-GLUTAMYLTRANSP
EPTIDASE

(Escherichia
coli) 		PF01019
(G_glu_transpept) 		3 SER A 145
ASP A 240
ASP A 266
 None
 0.74A 4uckA-2e0wA:
undetectable		 4uckA-2e0wA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e5v L-ASPARTATE OXIDASE

(Sulfurisphaera
tokodaii) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		3 SER A  47
ASP A 316
ASP A  60
 None
 0.80A 4uckA-2e5vA:
undetectable		 4uckA-2e5vA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eta TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 2

(Rattus
norvegicus) 		PF12796
(Ank_2) 		3 SER A 146
ASP A  78
ASP A 108
 None
 0.79A 4uckA-2etaA:
undetectable		 4uckA-2etaA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i0e PROTEIN KINASE
C-BETA II

(Homo sapiens) 		PF00069
(Pkinase)
PF00433
(Pkinase_C) 		3 SER A 552
ASP A 523
ASP A 506
 None
 0.79A 4uckA-2i0eA:
undetectable		 4uckA-2i0eA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jwp MALECTIN

(Xenopus laevis) 		PF11721
(Malectin) 		3 SER A  53
ASP A 116
ASP A 128
 None
 0.78A 4uckA-2jwpA:
undetectable		 4uckA-2jwpA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE

(Galdieria
sulphuraria) 		PF08241
(Methyltransf_11) 		3 SER A  63
ASP A  28
ASP A 158
 None
 0.77A 4uckA-2o57A:
5.6		 4uckA-2o57A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oas 4-HYDROXYBUTYRATE
COENZYME A
TRANSFERASE

(Shewanella
oneidensis) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		3 SER A 128
ASP A 237
ASP A 276
 None
 0.65A 4uckA-2oasA:
undetectable		 4uckA-2oasA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2obv S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1

(Homo sapiens) 		PF00438
(S-AdoMet_synt_N)
PF02772
(S-AdoMet_synt_M)
PF02773
(S-AdoMet_synt_C) 		3 SER A  73
ASP A  35
ASP A 286
 None
 0.60A 4uckA-2obvA:
undetectable		 4uckA-2obvA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE

(Homo sapiens) 		PF05770
(Ins134_P3_kin) 		3 SER X 214
ASP X 259
ASP X 281
 None
 0.73A 4uckA-2odtX:
undetectable		 4uckA-2odtX:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oy0 METHYLTRANSFERASE

(West Nile virus) 		PF01728
(FtsJ) 		3 SER A  56
ASP A 131
ASP A 146
 SAH  A 301 (-3.0A)
SAH  A 301 (-3.2A)
SAH  A 301 (-4.2A)
 0.62A 4uckA-2oy0A:
9.4		 4uckA-2oy0A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ozz HYPOTHETICAL PROTEIN
YHFZ

(Shigella
flexneri) 		PF14503
(YhfZ_C) 		3 SER A  75
ASP A 138
ASP A 120
 None
 0.79A 4uckA-2ozzA:
undetectable		 4uckA-2ozzA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pvs PANCREATIC
LIPASE-RELATED
PROTEIN 2

(Homo sapiens) 		PF00151
(Lipase)
PF01477
(PLAT) 		3 SER A 152
ASP A  34
ASP A  79
 None
 0.80A 4uckA-2pvsA:
undetectable		 4uckA-2pvsA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2px5 GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)]

(Murray Valley
encephalitis
virus) 		PF01728
(FtsJ) 		3 SER A  56
ASP A 131
ASP A 146
 SAH  A 500 (-2.5A)
SAH  A 500 (-3.5A)
SAH  A 500 (-3.6A)
 0.66A 4uckA-2px5A:
8.6		 4uckA-2px5A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qe8 UNCHARACTERIZED
PROTEIN

(Trichormus
variabilis) 		PF03022
(MRJP) 		3 SER A 105
ASP A 123
ASP A  74
 GOL  A 349 (-2.7A)
UNL  A 344 (-3.7A)
GOL  A 349 ( 4.9A)
 0.78A 4uckA-2qe8A:
undetectable		 4uckA-2qe8A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qza SECRETED EFFECTOR
PROTEIN

(Salmonella
enterica) 		PF13599
(Pentapeptide_4)
PF13979
(SopA_C)
PF13981
(SopA) 		3 SER A 236
ASP A 196
ASP A 201
 None
 0.78A 4uckA-2qzaA:
undetectable		 4uckA-2qzaA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rag DIPEPTIDASE

(Caulobacter
vibrioides) 		PF01244
(Peptidase_M19) 		3 SER A 161
ASP A 236
ASP A 226
 None
 0.79A 4uckA-2ragA:
undetectable		 4uckA-2ragA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rcc RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA

(Bacillus
halodurans) 		PF00268
(Ribonuc_red_sm) 		3 SER A 124
ASP A 181
ASP A 218
 None
 0.75A 4uckA-2rccA:
undetectable		 4uckA-2rccA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rk9 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE

(Vibrio
splendidus) 		no annotation 3 SER A 107
ASP A  83
ASP A 135
 None
 0.83A 4uckA-2rk9A:
undetectable		 4uckA-2rk9A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vfa HYPOXANTHINE-GUANINE
-XANTHINE
PHOSPHORIBOSYLTRANSF
ERASE,
HYPOXANTHINE-GUANINE
PHOSPHORIBOSYLTRANSF
ERASE

(Plasmodium
falciparum;
Homo sapiens) 		PF00156
(Pribosyltran) 		3 SER A 200
ASP A  60
ASP A  85
 None
 0.80A 4uckA-2vfaA:
2.3		 4uckA-2vfaA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpw THIOSULFATE
REDUCTASE

(Thermus
thermophilus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		3 SER A 105
ASP A 466
ASP A 477
 None
MGD  A1765 (-2.8A)
None
 0.76A 4uckA-2vpwA:
undetectable		 4uckA-2vpwA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x05 EXO-BETA-D-GLUCOSAMI
NIDASE

(Amycolatopsis
orientalis) 		PF00703
(Glyco_hydro_2)
PF02837
(Glyco_hydro_2_N) 		3 SER A 540
ASP A 473
ASP A 469
 None
None
X05  A1900 (-3.2A)
 0.82A 4uckA-2x05A:
undetectable		 4uckA-2x05A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yfu CARBOHYDRATE BINDING
FAMILY 6

(Ruminiclostridium
thermocellum) 		no annotation 3 SER A 125
ASP A  30
ASP A  36
 None
None
GOL  A1142 (-2.8A)
 0.68A 4uckA-2yfuA:
undetectable		 4uckA-2yfuA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zc2 DNAD-LIKE
REPLICATION PROTEIN

(Streptococcus
mutans) 		PF07261
(DnaB_2) 		3 SER A 163
ASP A 153
ASP A 157
 None
 0.76A 4uckA-2zc2A:
undetectable		 4uckA-2zc2A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyi LIPASE, PUTATIVE

(Archaeoglobus
fulgidus) 		PF00561
(Abhydrolase_1) 		3 SER A 148
ASP A  61
ASP A 108
 None
 0.77A 4uckA-2zyiA:
undetectable		 4uckA-2zyiA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3axi OLIGO-1,6-GLUCOSIDAS
E IMA1

(Saccharomyces
cerevisiae) 		PF00128
(Alpha-amylase) 		3 SER A 588
ASP A 519
ASP A 555
 None
 0.81A 4uckA-3axiA:
undetectable		 4uckA-3axiA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bg0 NUCLEOPORIN NUP145

(Saccharomyces
cerevisiae) 		PF12110
(Nup96) 		3 SER B 213
ASP B 186
ASP B 219
 None
 0.45A 4uckA-3bg0B:
undetectable		 4uckA-3bg0B:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bji PROTO-ONCOGENE VAV

(Homo sapiens) 		PF00130
(C1_1)
PF00169
(PH)
PF00621
(RhoGEF) 		3 SER A 291
ASP A 211
ASP A 324
 None
 0.81A 4uckA-3bjiA:
undetectable		 4uckA-3bjiA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3buz IOTA TOXIN COMPONENT
IA

(Clostridium
perfringens) 		PF03496
(ADPrib_exo_Tox) 		3 SER A 229
ASP A 212
ASP A 221
 None
 0.81A 4uckA-3buzA:
undetectable		 4uckA-3buzA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cn7 CARBOXYLESTERASE

(Pseudomonas
aeruginosa) 		PF02230
(Abhydrolase_2) 		3 SER A  65
ASP A 145
ASP A  79
 None
 0.82A 4uckA-3cn7A:
undetectable		 4uckA-3cn7A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3crj TRANSCRIPTION
REGULATOR

(Haloarcula
marismortui) 		PF00440
(TetR_N)
PF13977
(TetR_C_6) 		3 SER A 159
ASP A 144
ASP A 152
 None
 0.71A 4uckA-3crjA:
undetectable		 4uckA-3crjA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3f YVGN PROTEIN

(Bacillus
subtilis) 		PF00248
(Aldo_ket_red) 		3 SER A 213
ASP A   7
ASP A 244
 NDP  A   1 ( 4.9A)
None
None
 0.78A 4uckA-3d3fA:
undetectable		 4uckA-3d3fA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dz1 DIHYDRODIPICOLINATE
SYNTHASE

(Rhodopseudomonas
palustris) 		PF00701
(DHDPS) 		3 SER A 275
ASP A  57
ASP A  21
 None
 0.70A 4uckA-3dz1A:
undetectable		 4uckA-3dz1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e3m TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Ruegeria
pomeroyi) 		PF13377
(Peripla_BP_3) 		3 SER A  89
ASP A 257
ASP A 302
 None
 0.72A 4uckA-3e3mA:
undetectable		 4uckA-3e3mA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eb8 CYSTEINE
PROTEASE-LIKE VIRA

(Shigella
flexneri) 		PF06872
(EspG) 		3 SER A 346
ASP A 214
ASP A 189
 None
 0.75A 4uckA-3eb8A:
undetectable		 4uckA-3eb8A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eh7 4-HYDROXYBUTYRATE
COA-TRANSFERASE

(Porphyromonas
gingivalis) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		3 SER A 134
ASP A 243
ASP A 282
 None
 0.61A 4uckA-3eh7A:
undetectable		 4uckA-3eh7A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3evc RNA-DIRECTED RNA
POLYMERASE NS5

(Yellow fever
virus) 		PF01728
(FtsJ) 		3 SER A  56
ASP A 131
ASP A 146
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.78A 4uckA-3evcA:
9.3		 4uckA-3evcA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gcz POLYPROTEIN

(Yokose virus) 		PF01728
(FtsJ) 		3 SER A  56
ASP A 131
ASP A 146
 SAM  A4633 (-2.7A)
SAM  A4633 (-3.7A)
SAM  A4633 (-3.7A)
 0.78A 4uckA-3gczA:
9.6		 4uckA-3gczA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdo UNCHARACTERIZED
OXIDOREDUCTASE YVAA

(Bacillus
subtilis) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 SER A 305
ASP A 192
ASP A 262
 None
 0.77A 4uckA-3gdoA:
2.5		 4uckA-3gdoA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gnu 25 KDA PROTEIN
ELICITOR

(Pythium
aphanidermatum) 		PF05630
(NPP1) 		3 SER P 126
ASP P 191
ASP P 104
 None
 0.80A 4uckA-3gnuP:
undetectable		 4uckA-3gnuP:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hgo 12-OXOPHYTODIENOATE
REDUCTASE 3

(Solanum
lycopersicum) 		PF00724
(Oxidored_FMN) 		3 SER A 254
ASP A 205
ASP A 198
 None
 0.81A 4uckA-3hgoA:
undetectable		 4uckA-3hgoA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hkz DNA-DIRECTED RNA
POLYMERASE SUBUNIT
A'

(Sulfolobus
solfataricus) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		3 SER A 287
ASP A  46
ASP A 234
 None
 0.79A 4uckA-3hkzA:
undetectable		 4uckA-3hkzA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hpf MUCONATE
CYCLOISOMERASE

(Oceanobacillus
iheyensis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 SER A 268
ASP A 384
ASP A 322
 None
 0.82A 4uckA-3hpfA:
undetectable		 4uckA-3hpfA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hr6 PUTATIVE
SURFACE-ANCHORED
FIMBRIAL SUBUNIT

(Corynebacterium
diphtheriae) 		no annotation 3 SER A  88
ASP A 335
ASP A 341
 None
 0.57A 4uckA-3hr6A:
undetectable		 4uckA-3hr6A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvd PROTECTIVE ANTIGEN

(Bacillus
anthracis) 		PF03495
(Binary_toxB)
PF17475
(Binary_toxB_2)
PF17476
(Binary_toxB_3) 		3 SER A 296
ASP A 608
ASP A 599
 None
 0.77A 4uckA-3hvdA:
undetectable		 4uckA-3hvdA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i0w 8-OXOGUANINE-DNA-GLY
COSYLASE

(Clostridium
acetobutylicum) 		PF00730
(HhH-GPD)
PF07934
(OGG_N) 		3 SER A 121
ASP A  80
ASP A 114
 None
None
EDO  A 292 (-4.0A)
 0.80A 4uckA-3i0wA:
undetectable		 4uckA-3i0wA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ik4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Herpetosiphon
aurantiacus) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 SER A 148
ASP A 168
ASP A 141
 None
 0.73A 4uckA-3ik4A:
undetectable		 4uckA-3ik4A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jro FUSION PROTEIN OF
PROTEIN TRANSPORT
PROTEIN SEC13 AND
NUCLEOPORIN NUP145

(Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF12110
(Nup96) 		3 SER A1214
ASP A1187
ASP A1220
 None
 0.51A 4uckA-3jroA:
undetectable		 4uckA-3jroA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kog PUTATIVE
PORE-FORMING TOXIN

(Bacteroides
vulgatus) 		PF12985
(DUF3869) 		3 SER A 131
ASP A 183
ASP A 240
 None
 0.58A 4uckA-3kogA:
undetectable		 4uckA-3kogA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3krs TRIOSEPHOSPHATE
ISOMERASE

(Cryptosporidium
parvum) 		PF00121
(TIM) 		3 SER A  65
ASP A 158
ASP A  91
 None
 0.74A 4uckA-3krsA:
undetectable		 4uckA-3krsA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l2k EHPF

(Pantoea
agglomerans) 		PF00501
(AMP-binding) 		3 SER A 280
ASP A 345
ASP A 349
 None
 0.82A 4uckA-3l2kA:
undetectable		 4uckA-3l2kA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lkz NON-STRUCTURAL
PROTEIN 5

(West Nile virus) 		PF01728
(FtsJ) 		3 SER A  56
ASP A 131
ASP A 146
 SFG  A 301 (-2.6A)
SFG  A 301 (-3.1A)
SFG  A 301 (-3.8A)
 0.56A 4uckA-3lkzA:
8.8		 4uckA-3lkzA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ll3 GLUCONATE KINASE

(Lactobacillus
acidophilus) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		3 SER A 404
ASP A 310
ASP A 320
 ATP  A1760 ( 4.7A)
None
None
 0.53A 4uckA-3ll3A:
undetectable		 4uckA-3ll3A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lte RESPONSE REGULATOR

(Bermanella
marisrubri) 		PF00072
(Response_reg) 		3 SER A 132
ASP A  74
ASP A 125
 None
 0.83A 4uckA-3lteA:
undetectable		 4uckA-3lteA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lvv GLUTAMATE--CYSTEINE
LIGASE

(Saccharomyces
cerevisiae) 		PF03074
(GCS) 		3 SER A 628
ASP A 256
ASP A 229
 None
 0.80A 4uckA-3lvvA:
undetectable		 4uckA-3lvvA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE

(Methylobacillus
flagellatus) 		PF14403
(CP_ATPgrasp_2) 		3 SER A 349
ASP A 147
ASP A 319
 None
 0.80A 4uckA-3n6xA:
undetectable		 4uckA-3n6xA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nur AMIDOHYDROLASE

(Staphylococcus
aureus) 		PF04909
(Amidohydro_2) 		3 SER A 285
ASP A 173
ASP A 242
 None
 0.79A 4uckA-3nurA:
undetectable		 4uckA-3nurA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oit OS07G0271500 PROTEIN

(Oryza sativa) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		3 SER A 340
ASP A 286
ASP A 327
 None
 0.62A 4uckA-3oitA:
undetectable		 4uckA-3oitA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pfq PROTEIN KINASE C
BETA TYPE

(Rattus
norvegicus) 		PF00069
(Pkinase)
PF00130
(C1_1)
PF00168
(C2)
PF00433
(Pkinase_C) 		3 SER A 552
ASP A 523
ASP A 506
 None
 0.82A 4uckA-3pfqA:
undetectable		 4uckA-3pfqA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pgv HALOACID
DEHALOGENASE-LIKE
HYDROLASE

(Klebsiella
pneumoniae) 		PF08282
(Hydrolase_3) 		3 SER A 190
ASP A 240
ASP A 218
 None
None
CA  A 267 ( 4.5A)
 0.74A 4uckA-3pgvA:
undetectable		 4uckA-3pgvA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pu6 UNCHARACTERIZED
PROTEIN

(Wolinella
succinogenes) 		no annotation 3 SER A 131
ASP A  40
ASP A  15
 None
 0.81A 4uckA-3pu6A:
undetectable		 4uckA-3pu6A:
18.27