SIMILAR PATTERNS OF AMINO ACIDS FOR 4U95_B_MIYB1102_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dj2 ADENYLOSUCCINATE
SYNTHETASE


(Arabidopsis
thaliana)
PF00709
(Adenylsucc_synt)
5 SER A  22
ASP A  46
ILE A  47
ALA A  49
VAL A  86
None
1.09A 4u95B-1dj2A:
undetectable
4u95B-1dj2A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dj3 ADENYLOSUCCINATE
SYNTHETASE


(Triticum
aestivum)
PF00709
(Adenylsucc_synt)
5 SER A  21
ASP A  45
ILE A  46
ALA A  48
VAL A  85
None
1.07A 4u95B-1dj3A:
0.0
4u95B-1dj3A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1egz ENDOGLUCANASE Z

(Dickeya
chrysanthemi)
PF00150
(Cellulase)
6 SER A  25
GLY A 166
SER A 171
GLU A 133
ASN A 132
ALA A 147
None
1.49A 4u95B-1egzA:
0.8
4u95B-1egzA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1epx FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE


(Leishmania
mexicana)
PF00274
(Glycolytic)
5 GLY A 246
ASP A 209
ILE A 208
ALA A 253
VAL A 258
None
1.14A 4u95B-1epxA:
0.0
4u95B-1epxA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fft UBIQUINOL OXIDASE

(Escherichia
coli)
PF00116
(COX2)
PF06481
(COX_ARM)
5 SER B  42
ILE B 183
ALA B 185
VAL B 165
PHE B 163
None
0.95A 4u95B-1fftB:
2.2
4u95B-1fftB:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g01 ENDOGLUCANASE

(Bacillus sp.
KSM-635)
PF00150
(Cellulase)
PF03424
(CBM_17_28)
6 SER A 263
GLY A 416
SER A 421
GLU A 373
ASN A 372
ALA A 398
None
None
None
CD  A 591 (-2.2A)
CD  A 591 ( 4.8A)
None
1.39A 4u95B-1g01A:
0.4
4u95B-1g01A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8k ARSENITE OXIDASE

(Alcaligenes
faecalis)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
5 PHE A 752
GLY A 753
SER A 754
GLU A 747
ALA A 468
None
1.01A 4u95B-1g8kA:
0.0
4u95B-1g8kA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gri GROWTH FACTOR BOUND
PROTEIN 2


(Homo sapiens)
PF00017
(SH2)
PF00018
(SH3_1)
5 PHE A 167
GLY A 176
ILE A 183
ALA A 163
VAL A 210
None
1.10A 4u95B-1griA:
0.0
4u95B-1griA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hqz ACTIN-BINDING
PROTEIN


(Saccharomyces
cerevisiae)
PF00241
(Cofilin_ADF)
5 PHE 1  99
ASP 1   7
ILE 1   6
ALA 1 105
VAL 1 106
None
1.17A 4u95B-1hqz1:
undetectable
4u95B-1hqz1:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i2m REGULATOR OF
CHROMOSOME
CONDENSATION 1


(Homo sapiens)
PF00415
(RCC1)
5 GLY B 248
ASN B 181
ASP B 182
ALA B 178
VAL B 185
None
1.16A 4u95B-1i2mB:
undetectable
4u95B-1i2mB:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1prn PORIN

(Rhodobacter
blasticus)
PF13609
(Porin_4)
5 SER A 112
GLY A 165
ASP A  90
ALA A 134
VAL A  85
None
1.17A 4u95B-1prnA:
undetectable
4u95B-1prnA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tmh TRIOSEPHOSPHATE
ISOMERASE


(Escherichia
coli)
PF00121
(TIM)
5 GLU A 252
ASN A 249
ASP A 246
ILE A 247
VAL A 215
None
1.13A 4u95B-1tmhA:
undetectable
4u95B-1tmhA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tvp CELLULASE

(Pseudoalteromonas
haloplanktis)
PF00150
(Cellulase)
6 SER A  25
GLY A 168
SER A 173
GLU A 135
ASN A 134
ALA A 149
None
None
None
EPE  A 700 (-3.4A)
None
None
1.45A 4u95B-1tvpA:
undetectable
4u95B-1tvpA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ur4 GALACTANASE

(Bacillus
licheniformis)
PF07745
(Glyco_hydro_53)
5 GLY A 256
ASP A 227
ALA A 313
VAL A 259
PHE A 229
None
1.12A 4u95B-1ur4A:
undetectable
4u95B-1ur4A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wf7 ENIGMA HOMOLOGUE
PROTEIN


(Mus musculus)
PF00595
(PDZ)
5 SER A   8
ASN A  81
ASP A  57
ILE A  56
ALA A  61
None
1.00A 4u95B-1wf7A:
undetectable
4u95B-1wf7A:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wue MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY PROTEIN


(Enterococcus
faecalis)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
5 GLU A1122
ILE A1348
ALA A1300
VAL A1297
PHE A1045
None
1.13A 4u95B-1wueA:
undetectable
4u95B-1wueA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zq1 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT E


(Pyrococcus
abyssi)
PF02637
(GatB_Yqey)
PF02934
(GatB_N)
PF02938
(GAD)
5 GLY C 347
ASP C 339
ALA C 392
VAL C 396
PHE C 337
None
1.16A 4u95B-1zq1C:
2.6
4u95B-1zq1C:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2acg PROFILIN II

(Acanthamoeba
castellanii)
PF00235
(Profilin)
5 PHE A  60
SER A  57
ASP A  51
ALA A  44
PHE A  49
None
1.17A 4u95B-2acgA:
undetectable
4u95B-2acgA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c07 3-OXOACYL-(ACYL-CARR
IER PROTEIN)
REDUCTASE


(Plasmodium
falciparum)
PF13561
(adh_short_C2)
5 GLY A 202
ASN A 206
ILE A 200
ALA A 241
VAL A 297
None
1.12A 4u95B-2c07A:
undetectable
4u95B-2c07A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c47 CASEIN KINASE 1
GAMMA 2 ISOFORM


(Homo sapiens)
PF00069
(Pkinase)
5 GLU A  77
ILE A  74
ALA A  73
VAL A  72
PHE A  46
None
None
5ID  A1300 ( 3.8A)
None
None
0.97A 4u95B-2c47A:
2.6
4u95B-2c47A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c49 SUGAR KINASE MJ0406

(Methanocaldococcus
jannaschii)
PF00294
(PfkB)
5 SER A  86
ASP A  82
ILE A  83
ALA A  49
VAL A  50
None
1.04A 4u95B-2c49A:
undetectable
4u95B-2c49A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cy8 D-PHENYLGLYCINE
AMINOTRANSFERASE


(Pseudomonas
stutzeri)
PF00202
(Aminotran_3)
5 GLY A 360
ASN A 331
ASP A 332
ALA A 337
VAL A 421
None
1.14A 4u95B-2cy8A:
undetectable
4u95B-2cy8A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j0r HEMIN TRANSPORT
PROTEIN HEMS


(Yersinia
enterocolitica)
PF05171
(HemS)
5 GLY A  79
GLU A  82
ASN A  95
ASP A 100
PHE A 256
None
0.93A 4u95B-2j0rA:
undetectable
4u95B-2j0rA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4q 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING 1


(Saccharomyces
cerevisiae)
PF00393
(6PGD)
PF03446
(NAD_binding_2)
6 GLY A  14
GLU A 131
ASN A  16
ILE A  18
ALA A  30
VAL A  28
None
1.48A 4u95B-2p4qA:
2.3
4u95B-2p4qA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wrz L-ARABINOSE-BINDING
PERIPLASMIC PROTEIN


(Escherichia
coli)
PF00532
(Peripla_BP_1)
5 PHE A  61
GLY A   6
GLU A  34
ILE A  38
VAL A  40
None
1.08A 4u95B-2wrzA:
undetectable
4u95B-2wrzA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zds PUTATIVE DNA-BINDING
PROTEIN


(Streptomyces
coelicolor)
PF01261
(AP_endonuc_2)
PF07582
(AP_endonuc_2_N)
5 SER A  70
GLU A  32
ASP A 125
ALA A 116
ARG A 174
None
1.13A 4u95B-2zdsA:
undetectable
4u95B-2zdsA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dui BETA-GALACTOSIDE-BIN
DING LECTIN


(Gallus gallus)
PF00337
(Gal-bind_lectin)
5 GLY A  22
ASP A 125
ILE A  24
ALA A  84
PHE A  80
None
1.05A 4u95B-3duiA:
undetectable
4u95B-3duiA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04


(Sarcoptes
scabiei)
PF00089
(Trypsin)
5 SER A 107
ASP A  71
ILE A  56
ALA A  17
VAL A  18
None
1.02A 4u95B-3h7oA:
undetectable
4u95B-3h7oA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE


(Corynebacterium
diphtheriae)
no annotation 5 GLY A  34
SER A  33
GLU A  53
ILE A  75
ALA A  49
None
1.14A 4u95B-3hm2A:
undetectable
4u95B-3hm2A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hyi PROTEIN DUF199/WHIA

(Thermotoga
maritima)
PF02650
(HTH_WhiA)
PF10298
(WhiA_N)
PF14527
(LAGLIDADG_WhiA)
5 GLY A 160
ASN A 158
ASP A 177
ILE A 172
PHE A 181
None
1.10A 4u95B-3hyiA:
undetectable
4u95B-3hyiA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l5k HALOACID
DEHALOGENASE-LIKE
HYDROLASE
DOMAIN-CONTAINING
PROTEIN 1A


(Homo sapiens)
PF13419
(HAD_2)
5 GLY A 180
GLU A 182
ASP A 153
ILE A 154
ALA A 112
None
1.12A 4u95B-3l5kA:
undetectable
4u95B-3l5kA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o07 PYRIDOXINE
BIOSYNTHESIS PROTEIN
SNZ1


(Saccharomyces
cerevisiae)
PF01680
(SOR_SNZ)
5 ASN A  71
ASP A  68
ILE A  69
ALA A  30
VAL A  24
None
1.15A 4u95B-3o07A:
undetectable
4u95B-3o07A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE


(Salmonella
enterica)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
PF11890
(DUF3410)
5 PHE A  84
GLY A  83
ASN A  60
ALA A 273
VAL A 270
None
1.16A 4u95B-3oetA:
undetectable
4u95B-3oetA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qlt GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 2


(Rattus
norvegicus)
PF01094
(ANF_receptor)
5 PHE A 248
GLU A 254
ASN A 252
ILE A 250
PHE A 356
None
1.04A 4u95B-3qltA:
undetectable
4u95B-3qltA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1


(Bacillus
anthracis)
PF00275
(EPSP_synthase)
5 SER A 322
ASN A 356
ASP A 345
ILE A 346
VAL A 336
None
1.06A 4u95B-3sg1A:
undetectable
4u95B-3sg1A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t7v METHYLORNITHINE
SYNTHASE PYLB


(Methanosarcina
barkeri)
PF04055
(Radical_SAM)
5 GLY A 285
ASP A 279
ALA A 276
VAL A 297
ARG A 322
None
MD0  A 993 (-3.6A)
None
None
None
0.92A 4u95B-3t7vA:
undetectable
4u95B-3t7vA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqk PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE


(Francisella
tularensis)
PF00793
(DAHP_synth_1)
5 PHE A 158
GLU A  25
ASP A  30
ILE A  31
ARG A 129
None
1.01A 4u95B-3tqkA:
undetectable
4u95B-3tqkA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE


(Sulfurisphaera
tokodaii)
PF08443
(RimK)
5 GLU A 240
ASP A 237
ILE A 236
ALA A 225
VAL A 226
None
1.10A 4u95B-3vpcA:
undetectable
4u95B-3vpcA:
14.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9h ACRIFLAVINE
RESISTANCE PROTEIN B


(Escherichia
coli)
PF00873
(ACR_tran)
6 GLU A 273
ASP A 276
ILE A 277
ALA A 279
VAL A 612
ARG A 620
None
1.22A 4u95B-3w9hA:
60.4
4u95B-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9h ACRIFLAVINE
RESISTANCE PROTEIN B


(Escherichia
coli)
PF00873
(ACR_tran)
6 GLU A 273
ASP A 276
ILE A 277
ALA A 279
VAL A 612
PHE A 615
None
0.78A 4u95B-3w9hA:
60.4
4u95B-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9h ACRIFLAVINE
RESISTANCE PROTEIN B


(Escherichia
coli)
PF00873
(ACR_tran)
6 SER A  48
GLU A 273
ASP A 276
ILE A 277
VAL A 612
PHE A 615
None
0.92A 4u95B-3w9hA:
60.4
4u95B-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9h ACRIFLAVINE
RESISTANCE PROTEIN B


(Escherichia
coli)
PF00873
(ACR_tran)
5 SER A  48
PHE A 178
GLY A 179
SER A 180
GLU A 273
None
0.93A 4u95B-3w9hA:
60.4
4u95B-3w9hA:
99.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b3i FATTY ACID
BETA-OXIDATION
COMPLEX ALPHA-CHAIN
FADB


(Mycobacterium
tuberculosis)
PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N)
5 SER A 168
ASN A 164
ILE A 162
ALA A 268
VAL A 269
None
1.11A 4u95B-4b3iA:
4.4
4u95B-4b3iA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN


(Carboxydothermus
hydrogenoformans)
PF14574
(DUF4445)
5 GLY I 466
SER I 465
ASP I 469
ILE I 468
PHE I 486
None
0.84A 4u95B-4c1nI:
undetectable
4u95B-4c1nI:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cqm CARBONYL REDUCTASE
FAMILY MEMBER 4


(Homo sapiens)
PF13561
(adh_short_C2)
6 GLY B 138
SER B 149
ASN B 142
ILE B 136
ALA B 177
VAL B 228
None
1.13A 4u95B-4cqmB:
undetectable
4u95B-4cqmB:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0a PROTEIN WNT-8

(Xenopus laevis)
PF00110
(wnt)
5 ASN B 207
ASP B 204
ILE B 205
ALA B 172
VAL B 173
None
0.95A 4u95B-4f0aB:
undetectable
4u95B-4f0aB:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f3v ESX-1 SECRETION
SYSTEM PROTEIN ECCA1


(Mycobacterium
tuberculosis)
no annotation 5 SER A 131
PHE A 106
GLY A 105
ILE A 102
ALA A  58
None
1.12A 4u95B-4f3vA:
undetectable
4u95B-4f3vA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdg MINICHROMOSOME
MAINTENANCE PROTEIN
MCM


(Sulfolobus
solfataricus)
no annotation 5 SER B 368
ASP B 404
ILE B 403
ALA B 401
VAL B 443
None
1.05A 4u95B-4fdgB:
2.8
4u95B-4fdgB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fid G PROTEIN ALPHA
SUBUNIT


(Entamoeba
histolytica)
PF00503
(G-alpha)
5 GLY A  30
SER A  31
GLU A 230
ASP A 237
ILE A 238
None
1.12A 4u95B-4fidA:
undetectable
4u95B-4fidA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fus RTX TOXINS AND
RELATED CA2+-BINDING
PROTEIN


(Hahella
chejuensis)
PF02011
(Glyco_hydro_48)
5 PHE A 428
GLY A 430
ASP A 302
ALA A 408
VAL A 353
None
None
None
None
OHI  A 352 ( 3.1A)
1.13A 4u95B-4fusA:
undetectable
4u95B-4fusA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fyu THIOREDOXIN

(Wuchereria
bancrofti)
PF13905
(Thioredoxin_8)
5 GLY A  20
SER A  21
ASN A   7
ILE A   8
VAL A  89
None
1.10A 4u95B-4fyuA:
undetectable
4u95B-4fyuA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g9k ROTENONE-INSENSITIVE
NADH-UBIQUINONE
OXIDOREDUCTASE


(Saccharomyces
cerevisiae)
PF07992
(Pyr_redox_2)
5 GLY A  60
SER A  61
ILE A  82
ALA A 129
VAL A 139
GLY  A  60 (-0.0A)
SER  A  61 (-0.0A)
ILE  A  82 (-0.7A)
ALA  A 129 (-0.0A)
VAL  A 139 ( 0.6A)
0.84A 4u95B-4g9kA:
undetectable
4u95B-4g9kA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hkt INOSITOL
2-DEHYDROGENASE


(Sinorhizobium
meliloti)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
5 SER A 219
GLY A 243
SER A 244
ILE A 135
VAL A 131
None
1.02A 4u95B-4hktA:
undetectable
4u95B-4hktA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hkt INOSITOL
2-DEHYDROGENASE


(Sinorhizobium
meliloti)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
5 SER A 219
SER A 244
ILE A 135
ALA A 134
VAL A 131
None
1.08A 4u95B-4hktA:
undetectable
4u95B-4hktA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwt THREONINE--TRNA
LIGASE, CYTOPLASMIC


(Homo sapiens)
PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon)
5 PHE A 559
GLU A 564
ASN A 530
ASP A 578
ILE A 577
None
None
None
1B2  A 802 (-3.7A)
None
1.10A 4u95B-4hwtA:
undetectable
4u95B-4hwtA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iiv 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE


(Escherichia
coli)
PF13561
(adh_short_C2)
5 SER A   2
GLY A  51
ASN A  53
ILE A  47
ALA A  46
None
0.97A 4u95B-4iivA:
2.1
4u95B-4iivA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ipa PUTATIVE CURVED
DNA-BINDING PROTEIN


(Chaetomium
thermophilum)
PF00557
(Peptidase_M24)
5 GLY A  72
ASN A  70
ASP A 117
ILE A 116
ALA A  24
None
1.15A 4u95B-4ipaA:
2.7
4u95B-4ipaA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jdn VIRULENCE PLASMID
PROTEIN PGP3-D


(Chlamydia
trachomatis)
PF05475
(Chlam_vir)
5 SER A 194
ASP A 168
ILE A 169
ALA A 171
VAL A 235
None
1.07A 4u95B-4jdnA:
undetectable
4u95B-4jdnA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jdo VIRULENCE PLASMID
PROTEIN PGP3-D


(Chlamydia
trachomatis)
PF05475
(Chlam_vir)
5 SER A 194
ASP A 168
ILE A 169
ALA A 171
VAL A 235
None
1.07A 4u95B-4jdoA:
undetectable
4u95B-4jdoA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kq9 RIBOSE ABC
TRANSPORTER,
SUBSTRATE BINDING
PROTEIN


(Conexibacter
woesei)
PF13407
(Peripla_BP_4)
5 GLY A 150
SER A 151
ILE A 294
ALA A 295
VAL A 298
None
GOL  A 501 ( 4.9A)
None
None
None
1.02A 4u95B-4kq9A:
undetectable
4u95B-4kq9A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m1r CELLULASE 5

(soil metagenome)
PF00150
(Cellulase)
6 SER A  25
GLY A 165
SER A 170
GLU A 132
ASN A 131
ALA A 146
None
None
None
TRS  A 301 (-2.7A)
TRS  A 301 (-3.3A)
None
1.42A 4u95B-4m1rA:
undetectable
4u95B-4m1rA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nme PROLINE
DEHYDROGENASE AND
DELTA-1-PYRROLINE-5-
CARBOXYLATE
DEHYDROGENASE


(Geobacter
sulfurreducens)
PF00171
(Aldedh)
PF01619
(Pro_dh)
5 SER A 843
GLY A 731
SER A 732
GLU A 734
ALA A 652
None
1.16A 4u95B-4nmeA:
undetectable
4u95B-4nmeA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nt4 GILGAMESH, ISOFORM I

(Drosophila
melanogaster)
PF00069
(Pkinase)
5 GLU A  74
ILE A  71
ALA A  70
VAL A  69
PHE A  43
None
1.04A 4u95B-4nt4A:
undetectable
4u95B-4nt4A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pet EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 7


(Colwellia
psychrerythraea)
PF03480
(DctP)
5 GLU A 186
ILE A 312
ALA A 311
VAL A 308
PHE A 304
None
1.17A 4u95B-4petA:
undetectable
4u95B-4petA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfm 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE


(Shewanella
benthica)
PF00701
(DHDPS)
5 ASN A 156
ASP A 127
ILE A 128
ALA A  98
VAL A  97
None
1.17A 4u95B-4pfmA:
0.7
4u95B-4pfmA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qko PYOCIN-S2
PYOCIN-S2 IMMUNITY
PROTEIN


(Pseudomonas
aeruginosa)
PF01320
(Colicin_Pyocin)
no annotation
5 GLY B 628
ASP A  19
ILE A  20
VAL A  38
PHE A  41
None
1.09A 4u95B-4qkoB:
undetectable
4u95B-4qkoB:
7.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3t PENICILLIN-BINDING
PROTEIN 2


(Neisseria
gonorrhoeae)
PF00905
(Transpeptidase)
5 PHE A 315
SER A 419
ILE A 317
ALA A 318
VAL A 470
None
1.12A 4u95B-4u3tA:
undetectable
4u95B-4u3tA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN


(Salmonella
enterica)
PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl)
PF11974
(MG1)
5 SER A1624
SER A1375
GLU A1418
ILE A1370
ALA A1330
None
1.08A 4u95B-4u48A:
undetectable
4u95B-4u48A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ud8 FAD-BINDING AND BBE
DOMAIN-CONTAINING
PROTEIN


(Arabidopsis
thaliana)
PF01565
(FAD_binding_4)
PF08031
(BBE)
5 SER A 112
GLY A 237
ILE A 233
ALA A 232
VAL A 229
FAD  A 601 (-2.7A)
None
None
None
None
1.15A 4u95B-4ud8A:
undetectable
4u95B-4ud8A:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbd BSHC

(Bacillus
subtilis)
PF10079
(BshC)
5 GLY A 352
ASN A  12
ILE A 354
ALA A 349
VAL A 374
CIT  A 602 (-3.5A)
None
None
None
None
1.13A 4u95B-4wbdA:
5.2
4u95B-4wbdA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wmj GLUCOSE-6-PHOSPHATE
ISOMERASE


(Colias
eurytheme)
PF00342
(PGI)
5 PHE A 502
GLY A 505
ILE A 507
ALA A 324
ARG A  79
None
1.15A 4u95B-4wmjA:
undetectable
4u95B-4wmjA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wyu PROTEIN SCRIBBLE
HOMOLOG


(Homo sapiens)
PF00595
(PDZ)
5 GLY A  30
SER A  36
ILE A  28
ALA A  84
VAL A  85
None
1.04A 4u95B-4wyuA:
undetectable
4u95B-4wyuA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhg SIMILAR TO
UNIPROT|P29295
SACCHAROMYCES
CEREVISIAE YPL204W
HRR25


([Candida]
glabrata)
PF00069
(Pkinase)
5 GLU A  40
ILE A  37
ALA A  36
VAL A  35
PHE A   9
None
None
ADP  A 501 ( 3.7A)
None
None
1.06A 4u95B-4xhgA:
undetectable
4u95B-4xhgA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhl CASEIN KINASE I
HOMOLOG HRR25


(Saccharomyces
cerevisiae)
PF00069
(Pkinase)
5 GLU A  40
ILE A  37
ALA A  36
VAL A  35
PHE A   9
None
None
CKI  A 401 (-3.3A)
None
None
0.93A 4u95B-4xhlA:
undetectable
4u95B-4xhlA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xzb CELA

(Geobacillus sp.
70PC53)
PF00150
(Cellulase)
6 SER A  33
GLY A 177
SER A 182
GLU A 142
ASN A 141
ALA A 158
None
1.44A 4u95B-4xzbA:
undetectable
4u95B-4xzbA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xzw ENDO-GLUCANASE
CHIMERA C10


(Geobacillus sp.
70PC53;
uncultured
bacterium)
PF00150
(Cellulase)
6 SER A  33
GLY A 176
SER A 181
GLU A 142
ASN A 141
ALA A 157
None
None
None
EPE  A 404 (-3.3A)
None
None
1.45A 4u95B-4xzwA:
undetectable
4u95B-4xzwA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zze SUGAR BINDING
PROTEIN OF ABC
TRANSPORTER SYSTEM


(Bifidobacterium
animalis)
PF01547
(SBP_bac_1)
5 PHE A 123
GLY A 332
ASP A  53
PHE A  55
ARG A  96
None
1.17A 4u95B-4zzeA:
undetectable
4u95B-4zzeA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cm6 TRAP DICARBOXYLATE
TRANSPORTER-DCTP
SUBUNIT


(Pseudoalteromonas
atlantica)
PF03480
(DctP)
5 GLU A 180
ILE A 306
ALA A 305
VAL A 302
PHE A 298
None
1.11A 4u95B-5cm6A:
undetectable
4u95B-5cm6A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5emi CELL WALL
HYDROLASE/AUTOLYSIN


(Nostoc
punctiforme)
PF01520
(Amidase_3)
5 SER A 570
ASP A 444
ILE A 443
ALA A 474
VAL A 473
None
1.16A 4u95B-5emiA:
undetectable
4u95B-5emiA:
10.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eno MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB


(Escherichia
coli)
PF00873
(ACR_tran)
6 ASP A 276
ILE A 277
ALA A 279
VAL A 612
PHE A 615
ARG A 620
None
0.97A 4u95B-5enoA:
43.5
4u95B-5enoA:
73.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eno MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB


(Escherichia
coli)
PF00873
(ACR_tran)
5 PHE A 178
GLY A 179
SER A 180
GLU A 273
ASN A 274
None
1.05A 4u95B-5enoA:
43.5
4u95B-5enoA:
73.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eno MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB


(Escherichia
coli)
PF00873
(ACR_tran)
6 SER A  48
ASP A 276
ILE A 277
ALA A 279
VAL A 612
PHE A 615
None
1.02A 4u95B-5enoA:
43.5
4u95B-5enoA:
73.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eno MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB


(Escherichia
coli)
PF00873
(ACR_tran)
6 SER A  48
GLU A 273
ASP A 276
ILE A 277
ALA A 279
VAL A 612
None
0.83A 4u95B-5enoA:
43.5
4u95B-5enoA:
73.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eno MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB


(Escherichia
coli)
PF00873
(ACR_tran)
5 SER A  48
PHE A 178
GLY A 179
SER A 180
GLU A 273
None
0.71A 4u95B-5enoA:
43.5
4u95B-5enoA:
73.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f5o NUCLEOPROTEIN

(Marburg
marburgvirus)
PF05505
(Ebola_NP)
5 GLY A  45
ASN A  43
ASP A  40
ALA A 115
PHE A  99
None
1.13A 4u95B-5f5oA:
undetectable
4u95B-5f5oA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fzp DISPASE
AUTOLYSIS-INDUCING
PROTEIN


(Streptomyces
mobaraensis)
no annotation 5 SER A 118
GLY A  81
SER A  82
GLU A  99
ALA A  78
None
1.16A 4u95B-5fzpA:
undetectable
4u95B-5fzpA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN


(Cytophaga
hutchinsonii)
PF00150
(Cellulase)
6 SER A  55
GLY A 193
SER A 198
GLU A 159
ASN A 158
ALA A 174
None
1.41A 4u95B-5ihsA:
undetectable
4u95B-5ihsA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikj CRYPTIC LOCI
REGULATOR 2


(Schizosaccharomyces
pombe)
PF10383
(Clr2)
PF16761
(Clr2_transil)
5 PHE A 372
GLY A 374
ILE A 319
ALA A 510
VAL A 511
None
0.83A 4u95B-5ikjA:
undetectable
4u95B-5ikjA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjd COLLAGEN TYPE IV
ALPHA-3-BINDING
PROTEIN


(Homo sapiens)
PF01852
(START)
5 SER B 382
ASN B 556
ILE B 523
ALA B 521
VAL B 480
None
None
PEG  B 601 ( 3.7A)
PEG  B 601 ( 3.9A)
None
1.14A 4u95B-5jjdB:
2.1
4u95B-5jjdB:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jvb PHOSPHONATE ABC
TRANSPORTER,
PERIPLASMIC
PHOSPHONATE-BINDING
PROTEIN


(Trichodesmium
erythraeum)
no annotation 5 GLY A 170
GLU A 109
ILE A 122
ALA A 124
VAL A 155
None
1.01A 4u95B-5jvbA:
undetectable
4u95B-5jvbA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6u BETA-MANNOSIDASE

(Dictyoglomus
thermophilum)
PF00703
(Glyco_hydro_2)
PF02837
(Glyco_hydro_2_N)
6 PHE A 383
GLY A 422
SER A 467
ASN A 426
ILE A 446
VAL A 450
None
1.43A 4u95B-5n6uA:
undetectable
4u95B-5n6uA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ngj TAIL TUBE PROTEIN

(Escherichia
virus T5)
no annotation 5 PHE A 255
GLY A 257
GLU A 260
ASN A 234
ILE A 237
None
1.16A 4u95B-5ngjA:
undetectable
4u95B-5ngjA:
6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER


(Proteus
mirabilis)
no annotation 5 GLY A 174
ASP A 182
ILE A 179
VAL A  45
ARG A 260
None
NA  A 502 (-2.1A)
None
None
NA  A 502 ( 4.5A)
1.11A 4u95B-5nvaA:
1.7
4u95B-5nvaA:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oko PHOSPHATIDYLINOSITOL
3,4,5-TRISPHOSPHATE
5-PHOSPHATASE 2


(Homo sapiens)
PF03372
(Exo_endo_phos)
5 SER A 716
PHE A 605
GLY A 606
ALA A 543
VAL A 544
None
1.15A 4u95B-5okoA:
undetectable
4u95B-5okoA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uqc DIHYDROPYRIMIDINASE-
RELATED PROTEIN 2


(Mus musculus)
PF01979
(Amidohydro_1)
5 SER A 282
SER A 259
GLU A 229
ILE A 264
ALA A 267
None
1.15A 4u95B-5uqcA:
undetectable
4u95B-5uqcA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vld HISTIDINOL
DEHYDROGENASE,
CHLOROPLASTIC


(Medicago
truncatula)
PF00815
(Histidinol_dh)
5 ASN A 320
ASP A 318
ILE A 322
ALA A 293
VAL A 292
None
1.15A 4u95B-5vldA:
undetectable
4u95B-5vldA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aph ADENOSYLHOMOCYSTEINA
SE


(Elizabethkingia
anophelis)
PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase)
5 SER A 360
GLU A  24
ILE A  95
ALA A  96
VAL A 102
None
1.15A 4u95B-6aphA:
undetectable
4u95B-6aphA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ey4 GLDM

(Flavobacterium
johnsoniae)
no annotation 6 GLY A 370
ASN A 354
ILE A 356
ALA A 358
VAL A 386
PHE A 348
None
1.42A 4u95B-6ey4A:
3.5
4u95B-6ey4A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbn -

(-)
no annotation 5 SER A 358
GLU A  22
ILE A  93
ALA A  94
VAL A 100
None
1.14A 4u95B-6gbnA:
1.5
4u95B-6gbnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gjt -

(-)
no annotation 5 SER A 194
ASP A 168
ILE A 169
ALA A 171
VAL A 235
None
1.02A 4u95B-6gjtA:
undetectable
4u95B-6gjtA:
undetectable