SIMILAR PATTERNS OF AMINO ACIDS FOR 4U95_B_MIYB1102
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dj2 | ADENYLOSUCCINATESYNTHETASE (Arabidopsisthaliana) |
PF00709(Adenylsucc_synt) | 5 | SER A 22ASP A 46ILE A 47ALA A 49VAL A 86 | None | 1.09A | 4u95B-1dj2A:undetectable | 4u95B-1dj2A:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dj3 | ADENYLOSUCCINATESYNTHETASE (Triticumaestivum) |
PF00709(Adenylsucc_synt) | 5 | SER A 21ASP A 45ILE A 46ALA A 48VAL A 85 | None | 1.07A | 4u95B-1dj3A:0.0 | 4u95B-1dj3A:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1egz | ENDOGLUCANASE Z (Dickeyachrysanthemi) |
PF00150(Cellulase) | 6 | SER A 25GLY A 166SER A 171GLU A 133ASN A 132ALA A 147 | None | 1.49A | 4u95B-1egzA:0.8 | 4u95B-1egzA:13.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1epx | FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE (Leishmaniamexicana) |
PF00274(Glycolytic) | 5 | GLY A 246ASP A 209ILE A 208ALA A 253VAL A 258 | None | 1.14A | 4u95B-1epxA:0.0 | 4u95B-1epxA:15.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fft | UBIQUINOL OXIDASE (Escherichiacoli) |
PF00116(COX2)PF06481(COX_ARM) | 5 | SER B 42ILE B 183ALA B 185VAL B 165PHE B 163 | None | 0.95A | 4u95B-1fftB:2.2 | 4u95B-1fftB:15.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g01 | ENDOGLUCANASE (Bacillus sp.KSM-635) |
PF00150(Cellulase)PF03424(CBM_17_28) | 6 | SER A 263GLY A 416SER A 421GLU A 373ASN A 372ALA A 398 | NoneNoneNone CD A 591 (-2.2A) CD A 591 ( 4.8A)None | 1.39A | 4u95B-1g01A:0.4 | 4u95B-1g01A:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g8k | ARSENITE OXIDASE (Alcaligenesfaecalis) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | PHE A 752GLY A 753SER A 754GLU A 747ALA A 468 | None | 1.01A | 4u95B-1g8kA:0.0 | 4u95B-1g8kA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gri | GROWTH FACTOR BOUNDPROTEIN 2 (Homo sapiens) |
PF00017(SH2)PF00018(SH3_1) | 5 | PHE A 167GLY A 176ILE A 183ALA A 163VAL A 210 | None | 1.10A | 4u95B-1griA:0.0 | 4u95B-1griA:11.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hqz | ACTIN-BINDINGPROTEIN (Saccharomycescerevisiae) |
PF00241(Cofilin_ADF) | 5 | PHE 1 99ASP 1 7ILE 1 6ALA 1 105VAL 1 106 | None | 1.17A | 4u95B-1hqz1:undetectable | 4u95B-1hqz1:9.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i2m | REGULATOR OFCHROMOSOMECONDENSATION 1 (Homo sapiens) |
PF00415(RCC1) | 5 | GLY B 248ASN B 181ASP B 182ALA B 178VAL B 185 | None | 1.16A | 4u95B-1i2mB:undetectable | 4u95B-1i2mB:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1prn | PORIN (Rhodobacterblasticus) |
PF13609(Porin_4) | 5 | SER A 112GLY A 165ASP A 90ALA A 134VAL A 85 | None | 1.17A | 4u95B-1prnA:undetectable | 4u95B-1prnA:14.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tmh | TRIOSEPHOSPHATEISOMERASE (Escherichiacoli) |
PF00121(TIM) | 5 | GLU A 252ASN A 249ASP A 246ILE A 247VAL A 215 | None | 1.13A | 4u95B-1tmhA:undetectable | 4u95B-1tmhA:13.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tvp | CELLULASE (Pseudoalteromonashaloplanktis) |
PF00150(Cellulase) | 6 | SER A 25GLY A 168SER A 173GLU A 135ASN A 134ALA A 149 | NoneNoneNoneEPE A 700 (-3.4A)NoneNone | 1.45A | 4u95B-1tvpA:undetectable | 4u95B-1tvpA:14.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ur4 | GALACTANASE (Bacilluslicheniformis) |
PF07745(Glyco_hydro_53) | 5 | GLY A 256ASP A 227ALA A 313VAL A 259PHE A 229 | None | 1.12A | 4u95B-1ur4A:undetectable | 4u95B-1ur4A:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wf7 | ENIGMA HOMOLOGUEPROTEIN (Mus musculus) |
PF00595(PDZ) | 5 | SER A 8ASN A 81ASP A 57ILE A 56ALA A 61 | None | 1.00A | 4u95B-1wf7A:undetectable | 4u95B-1wf7A:7.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wue | MANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY PROTEIN (Enterococcusfaecalis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | GLU A1122ILE A1348ALA A1300VAL A1297PHE A1045 | None | 1.13A | 4u95B-1wueA:undetectable | 4u95B-1wueA:16.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zq1 | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT E (Pyrococcusabyssi) |
PF02637(GatB_Yqey)PF02934(GatB_N)PF02938(GAD) | 5 | GLY C 347ASP C 339ALA C 392VAL C 396PHE C 337 | None | 1.16A | 4u95B-1zq1C:2.6 | 4u95B-1zq1C:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2acg | PROFILIN II (Acanthamoebacastellanii) |
PF00235(Profilin) | 5 | PHE A 60SER A 57ASP A 51ALA A 44PHE A 49 | None | 1.17A | 4u95B-2acgA:undetectable | 4u95B-2acgA:8.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c07 | 3-OXOACYL-(ACYL-CARRIER PROTEIN)REDUCTASE (Plasmodiumfalciparum) |
PF13561(adh_short_C2) | 5 | GLY A 202ASN A 206ILE A 200ALA A 241VAL A 297 | None | 1.12A | 4u95B-2c07A:undetectable | 4u95B-2c07A:12.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c47 | CASEIN KINASE 1GAMMA 2 ISOFORM (Homo sapiens) |
PF00069(Pkinase) | 5 | GLU A 77ILE A 74ALA A 73VAL A 72PHE A 46 | NoneNone5ID A1300 ( 3.8A)NoneNone | 0.97A | 4u95B-2c47A:2.6 | 4u95B-2c47A:14.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c49 | SUGAR KINASE MJ0406 (Methanocaldococcusjannaschii) |
PF00294(PfkB) | 5 | SER A 86ASP A 82ILE A 83ALA A 49VAL A 50 | None | 1.04A | 4u95B-2c49A:undetectable | 4u95B-2c49A:15.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cy8 | D-PHENYLGLYCINEAMINOTRANSFERASE (Pseudomonasstutzeri) |
PF00202(Aminotran_3) | 5 | GLY A 360ASN A 331ASP A 332ALA A 337VAL A 421 | None | 1.14A | 4u95B-2cy8A:undetectable | 4u95B-2cy8A:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j0r | HEMIN TRANSPORTPROTEIN HEMS (Yersiniaenterocolitica) |
PF05171(HemS) | 5 | GLY A 79GLU A 82ASN A 95ASP A 100PHE A 256 | None | 0.93A | 4u95B-2j0rA:undetectable | 4u95B-2j0rA:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p4q | 6-PHOSPHOGLUCONATEDEHYDROGENASE,DECARBOXYLATING 1 (Saccharomycescerevisiae) |
PF00393(6PGD)PF03446(NAD_binding_2) | 6 | GLY A 14GLU A 131ASN A 16ILE A 18ALA A 30VAL A 28 | None | 1.48A | 4u95B-2p4qA:2.3 | 4u95B-2p4qA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wrz | L-ARABINOSE-BINDINGPERIPLASMIC PROTEIN (Escherichiacoli) |
PF00532(Peripla_BP_1) | 5 | PHE A 61GLY A 6GLU A 34ILE A 38VAL A 40 | None | 1.08A | 4u95B-2wrzA:undetectable | 4u95B-2wrzA:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zds | PUTATIVE DNA-BINDINGPROTEIN (Streptomycescoelicolor) |
PF01261(AP_endonuc_2)PF07582(AP_endonuc_2_N) | 5 | SER A 70GLU A 32ASP A 125ALA A 116ARG A 174 | None | 1.13A | 4u95B-2zdsA:undetectable | 4u95B-2zdsA:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dui | BETA-GALACTOSIDE-BINDING LECTIN (Gallus gallus) |
PF00337(Gal-bind_lectin) | 5 | GLY A 22ASP A 125ILE A 24ALA A 84PHE A 80 | None | 1.05A | 4u95B-3duiA:undetectable | 4u95B-3duiA:8.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7o | GROUP 3 ALLERGENSMIPP-S YV6023A04 (Sarcoptesscabiei) |
PF00089(Trypsin) | 5 | SER A 107ASP A 71ILE A 56ALA A 17VAL A 18 | None | 1.02A | 4u95B-3h7oA:undetectable | 4u95B-3h7oA:11.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hm2 | PRECORRIN-6YC5,15-METHYLTRANSFERASE (Corynebacteriumdiphtheriae) |
no annotation | 5 | GLY A 34SER A 33GLU A 53ILE A 75ALA A 49 | None | 1.14A | 4u95B-3hm2A:undetectable | 4u95B-3hm2A:11.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hyi | PROTEIN DUF199/WHIA (Thermotogamaritima) |
PF02650(HTH_WhiA)PF10298(WhiA_N)PF14527(LAGLIDADG_WhiA) | 5 | GLY A 160ASN A 158ASP A 177ILE A 172PHE A 181 | None | 1.10A | 4u95B-3hyiA:undetectable | 4u95B-3hyiA:13.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l5k | HALOACIDDEHALOGENASE-LIKEHYDROLASEDOMAIN-CONTAININGPROTEIN 1A (Homo sapiens) |
PF13419(HAD_2) | 5 | GLY A 180GLU A 182ASP A 153ILE A 154ALA A 112 | None | 1.12A | 4u95B-3l5kA:undetectable | 4u95B-3l5kA:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o07 | PYRIDOXINEBIOSYNTHESIS PROTEINSNZ1 (Saccharomycescerevisiae) |
PF01680(SOR_SNZ) | 5 | ASN A 71ASP A 68ILE A 69ALA A 30VAL A 24 | None | 1.15A | 4u95B-3o07A:undetectable | 4u95B-3o07A:13.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oet | ERYTHRONATE-4-PHOSPHATE DEHYDROGENASE (Salmonellaenterica) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C)PF11890(DUF3410) | 5 | PHE A 84GLY A 83ASN A 60ALA A 273VAL A 270 | None | 1.16A | 4u95B-3oetA:undetectable | 4u95B-3oetA:18.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qlt | GLUTAMATE RECEPTOR,IONOTROPIC KAINATE 2 (Rattusnorvegicus) |
PF01094(ANF_receptor) | 5 | PHE A 248GLU A 254ASN A 252ILE A 250PHE A 356 | None | 1.04A | 4u95B-3qltA:undetectable | 4u95B-3qltA:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sg1 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE 1 (Bacillusanthracis) |
PF00275(EPSP_synthase) | 5 | SER A 322ASN A 356ASP A 345ILE A 346VAL A 336 | None | 1.06A | 4u95B-3sg1A:undetectable | 4u95B-3sg1A:18.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t7v | METHYLORNITHINESYNTHASE PYLB (Methanosarcinabarkeri) |
PF04055(Radical_SAM) | 5 | GLY A 285ASP A 279ALA A 276VAL A 297ARG A 322 | NoneMD0 A 993 (-3.6A)NoneNoneNone | 0.92A | 4u95B-3t7vA:undetectable | 4u95B-3t7vA:17.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqk | PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATEALDOLASE (Francisellatularensis) |
PF00793(DAHP_synth_1) | 5 | PHE A 158GLU A 25ASP A 30ILE A 31ARG A 129 | None | 1.01A | 4u95B-3tqkA:undetectable | 4u95B-3tqkA:15.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vpc | PUTATIVEACETYLORNITHINEDEACETYLASE (Sulfurisphaeratokodaii) |
PF08443(RimK) | 5 | GLU A 240ASP A 237ILE A 236ALA A 225VAL A 226 | None | 1.10A | 4u95B-3vpcA:undetectable | 4u95B-3vpcA:14.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w9h | ACRIFLAVINERESISTANCE PROTEIN B (Escherichiacoli) |
PF00873(ACR_tran) | 6 | GLU A 273ASP A 276ILE A 277ALA A 279VAL A 612ARG A 620 | None | 1.22A | 4u95B-3w9hA:60.4 | 4u95B-3w9hA:99.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w9h | ACRIFLAVINERESISTANCE PROTEIN B (Escherichiacoli) |
PF00873(ACR_tran) | 6 | GLU A 273ASP A 276ILE A 277ALA A 279VAL A 612PHE A 615 | None | 0.78A | 4u95B-3w9hA:60.4 | 4u95B-3w9hA:99.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w9h | ACRIFLAVINERESISTANCE PROTEIN B (Escherichiacoli) |
PF00873(ACR_tran) | 6 | SER A 48GLU A 273ASP A 276ILE A 277VAL A 612PHE A 615 | None | 0.92A | 4u95B-3w9hA:60.4 | 4u95B-3w9hA:99.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w9h | ACRIFLAVINERESISTANCE PROTEIN B (Escherichiacoli) |
PF00873(ACR_tran) | 5 | SER A 48PHE A 178GLY A 179SER A 180GLU A 273 | None | 0.93A | 4u95B-3w9hA:60.4 | 4u95B-3w9hA:99.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b3i | FATTY ACIDBETA-OXIDATIONCOMPLEX ALPHA-CHAINFADB (Mycobacteriumtuberculosis) |
PF00378(ECH_1)PF00725(3HCDH)PF02737(3HCDH_N) | 5 | SER A 168ASN A 164ILE A 162ALA A 268VAL A 269 | None | 1.11A | 4u95B-4b3iA:4.4 | 4u95B-4b3iA:23.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c1n | IRON-SULFUR CLUSTERBINDING PROTEIN (Carboxydothermushydrogenoformans) |
PF14574(DUF4445) | 5 | GLY I 466SER I 465ASP I 469ILE I 468PHE I 486 | None | 0.84A | 4u95B-4c1nI:undetectable | 4u95B-4c1nI:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cqm | CARBONYL REDUCTASEFAMILY MEMBER 4 (Homo sapiens) |
PF13561(adh_short_C2) | 6 | GLY B 138SER B 149ASN B 142ILE B 136ALA B 177VAL B 228 | None | 1.13A | 4u95B-4cqmB:undetectable | 4u95B-4cqmB:13.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0a | PROTEIN WNT-8 (Xenopus laevis) |
PF00110(wnt) | 5 | ASN B 207ASP B 204ILE B 205ALA B 172VAL B 173 | None | 0.95A | 4u95B-4f0aB:undetectable | 4u95B-4f0aB:13.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f3v | ESX-1 SECRETIONSYSTEM PROTEIN ECCA1 (Mycobacteriumtuberculosis) |
no annotation | 5 | SER A 131PHE A 106GLY A 105ILE A 102ALA A 58 | None | 1.12A | 4u95B-4f3vA:undetectable | 4u95B-4f3vA:14.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdg | MINICHROMOSOMEMAINTENANCE PROTEINMCM (Sulfolobussolfataricus) |
no annotation | 5 | SER B 368ASP B 404ILE B 403ALA B 401VAL B 443 | None | 1.05A | 4u95B-4fdgB:2.8 | 4u95B-4fdgB:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fid | G PROTEIN ALPHASUBUNIT (Entamoebahistolytica) |
PF00503(G-alpha) | 5 | GLY A 30SER A 31GLU A 230ASP A 237ILE A 238 | None | 1.12A | 4u95B-4fidA:undetectable | 4u95B-4fidA:15.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fus | RTX TOXINS ANDRELATED CA2+-BINDINGPROTEIN (Hahellachejuensis) |
PF02011(Glyco_hydro_48) | 5 | PHE A 428GLY A 430ASP A 302ALA A 408VAL A 353 | NoneNoneNoneNoneOHI A 352 ( 3.1A) | 1.13A | 4u95B-4fusA:undetectable | 4u95B-4fusA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fyu | THIOREDOXIN (Wuchereriabancrofti) |
PF13905(Thioredoxin_8) | 5 | GLY A 20SER A 21ASN A 7ILE A 8VAL A 89 | None | 1.10A | 4u95B-4fyuA:undetectable | 4u95B-4fyuA:9.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g9k | ROTENONE-INSENSITIVENADH-UBIQUINONEOXIDOREDUCTASE (Saccharomycescerevisiae) |
PF07992(Pyr_redox_2) | 5 | GLY A 60SER A 61ILE A 82ALA A 129VAL A 139 | GLY A 60 (-0.0A)SER A 61 (-0.0A)ILE A 82 (-0.7A)ALA A 129 (-0.0A)VAL A 139 ( 0.6A) | 0.84A | 4u95B-4g9kA:undetectable | 4u95B-4g9kA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hkt | INOSITOL2-DEHYDROGENASE (Sinorhizobiummeliloti) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | SER A 219GLY A 243SER A 244ILE A 135VAL A 131 | None | 1.02A | 4u95B-4hktA:undetectable | 4u95B-4hktA:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hkt | INOSITOL2-DEHYDROGENASE (Sinorhizobiummeliloti) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | SER A 219SER A 244ILE A 135ALA A 134VAL A 131 | None | 1.08A | 4u95B-4hktA:undetectable | 4u95B-4hktA:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hwt | THREONINE--TRNALIGASE, CYTOPLASMIC (Homo sapiens) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon) | 5 | PHE A 559GLU A 564ASN A 530ASP A 578ILE A 577 | NoneNoneNone1B2 A 802 (-3.7A)None | 1.10A | 4u95B-4hwtA:undetectable | 4u95B-4hwtA:17.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iiv | 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (Escherichiacoli) |
PF13561(adh_short_C2) | 5 | SER A 2GLY A 51ASN A 53ILE A 47ALA A 46 | None | 0.97A | 4u95B-4iivA:2.1 | 4u95B-4iivA:14.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ipa | PUTATIVE CURVEDDNA-BINDING PROTEIN (Chaetomiumthermophilum) |
PF00557(Peptidase_M24) | 5 | GLY A 72ASN A 70ASP A 117ILE A 116ALA A 24 | None | 1.15A | 4u95B-4ipaA:2.7 | 4u95B-4ipaA:18.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jdn | VIRULENCE PLASMIDPROTEIN PGP3-D (Chlamydiatrachomatis) |
PF05475(Chlam_vir) | 5 | SER A 194ASP A 168ILE A 169ALA A 171VAL A 235 | None | 1.07A | 4u95B-4jdnA:undetectable | 4u95B-4jdnA:10.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jdo | VIRULENCE PLASMIDPROTEIN PGP3-D (Chlamydiatrachomatis) |
PF05475(Chlam_vir) | 5 | SER A 194ASP A 168ILE A 169ALA A 171VAL A 235 | None | 1.07A | 4u95B-4jdoA:undetectable | 4u95B-4jdoA:12.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kq9 | RIBOSE ABCTRANSPORTER,SUBSTRATE BINDINGPROTEIN (Conexibacterwoesei) |
PF13407(Peripla_BP_4) | 5 | GLY A 150SER A 151ILE A 294ALA A 295VAL A 298 | NoneGOL A 501 ( 4.9A)NoneNoneNone | 1.02A | 4u95B-4kq9A:undetectable | 4u95B-4kq9A:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m1r | CELLULASE 5 (soil metagenome) |
PF00150(Cellulase) | 6 | SER A 25GLY A 165SER A 170GLU A 132ASN A 131ALA A 146 | NoneNoneNoneTRS A 301 (-2.7A)TRS A 301 (-3.3A)None | 1.42A | 4u95B-4m1rA:undetectable | 4u95B-4m1rA:13.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nme | PROLINEDEHYDROGENASE ANDDELTA-1-PYRROLINE-5-CARBOXYLATEDEHYDROGENASE (Geobactersulfurreducens) |
PF00171(Aldedh)PF01619(Pro_dh) | 5 | SER A 843GLY A 731SER A 732GLU A 734ALA A 652 | None | 1.16A | 4u95B-4nmeA:undetectable | 4u95B-4nmeA:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nt4 | GILGAMESH, ISOFORM I (Drosophilamelanogaster) |
PF00069(Pkinase) | 5 | GLU A 74ILE A 71ALA A 70VAL A 69PHE A 43 | None | 1.04A | 4u95B-4nt4A:undetectable | 4u95B-4nt4A:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pet | EXTRACELLULARSOLUTE-BINDINGPROTEIN, FAMILY 7 (Colwelliapsychrerythraea) |
PF03480(DctP) | 5 | GLU A 186ILE A 312ALA A 311VAL A 308PHE A 304 | None | 1.17A | 4u95B-4petA:undetectable | 4u95B-4petA:15.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pfm | 4-HYDROXY-TETRAHYDRODIPICOLINATESYNTHASE (Shewanellabenthica) |
PF00701(DHDPS) | 5 | ASN A 156ASP A 127ILE A 128ALA A 98VAL A 97 | None | 1.17A | 4u95B-4pfmA:0.7 | 4u95B-4pfmA:15.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qko | PYOCIN-S2PYOCIN-S2 IMMUNITYPROTEIN (Pseudomonasaeruginosa) |
PF01320(Colicin_Pyocin)no annotation | 5 | GLY B 628ASP A 19ILE A 20VAL A 38PHE A 41 | None | 1.09A | 4u95B-4qkoB:undetectable | 4u95B-4qkoB:7.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u3t | PENICILLIN-BINDINGPROTEIN 2 (Neisseriagonorrhoeae) |
PF00905(Transpeptidase) | 5 | PHE A 315SER A 419ILE A 317ALA A 318VAL A 470 | None | 1.12A | 4u95B-4u3tA:undetectable | 4u95B-4u3tA:16.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u48 | PUTATIVE INNERMEMBRANE LIPOPROTEIN (Salmonellaenterica) |
PF00207(A2M)PF01835(A2M_N)PF07703(A2M_N_2)PF10569(Thiol-ester_cl)PF11974(MG1) | 5 | SER A1624SER A1375GLU A1418ILE A1370ALA A1330 | None | 1.08A | 4u95B-4u48A:undetectable | 4u95B-4u48A:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ud8 | FAD-BINDING AND BBEDOMAIN-CONTAININGPROTEIN (Arabidopsisthaliana) |
PF01565(FAD_binding_4)PF08031(BBE) | 5 | SER A 112GLY A 237ILE A 233ALA A 232VAL A 229 | FAD A 601 (-2.7A)NoneNoneNoneNone | 1.15A | 4u95B-4ud8A:undetectable | 4u95B-4ud8A:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wbd | BSHC (Bacillussubtilis) |
PF10079(BshC) | 5 | GLY A 352ASN A 12ILE A 354ALA A 349VAL A 374 | CIT A 602 (-3.5A)NoneNoneNoneNone | 1.13A | 4u95B-4wbdA:5.2 | 4u95B-4wbdA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wmj | GLUCOSE-6-PHOSPHATEISOMERASE (Coliaseurytheme) |
PF00342(PGI) | 5 | PHE A 502GLY A 505ILE A 507ALA A 324ARG A 79 | None | 1.15A | 4u95B-4wmjA:undetectable | 4u95B-4wmjA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wyu | PROTEIN SCRIBBLEHOMOLOG (Homo sapiens) |
PF00595(PDZ) | 5 | GLY A 30SER A 36ILE A 28ALA A 84VAL A 85 | None | 1.04A | 4u95B-4wyuA:undetectable | 4u95B-4wyuA:12.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xhg | SIMILAR TOUNIPROT|P29295SACCHAROMYCESCEREVISIAE YPL204WHRR25 ([Candida]glabrata) |
PF00069(Pkinase) | 5 | GLU A 40ILE A 37ALA A 36VAL A 35PHE A 9 | NoneNoneADP A 501 ( 3.7A)NoneNone | 1.06A | 4u95B-4xhgA:undetectable | 4u95B-4xhgA:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xhl | CASEIN KINASE IHOMOLOG HRR25 (Saccharomycescerevisiae) |
PF00069(Pkinase) | 5 | GLU A 40ILE A 37ALA A 36VAL A 35PHE A 9 | NoneNoneCKI A 401 (-3.3A)NoneNone | 0.93A | 4u95B-4xhlA:undetectable | 4u95B-4xhlA:17.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xzb | CELA (Geobacillus sp.70PC53) |
PF00150(Cellulase) | 6 | SER A 33GLY A 177SER A 182GLU A 142ASN A 141ALA A 158 | None | 1.44A | 4u95B-4xzbA:undetectable | 4u95B-4xzbA:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xzw | ENDO-GLUCANASECHIMERA C10 (Geobacillus sp.70PC53;unculturedbacterium) |
PF00150(Cellulase) | 6 | SER A 33GLY A 176SER A 181GLU A 142ASN A 141ALA A 157 | NoneNoneNoneEPE A 404 (-3.3A)NoneNone | 1.45A | 4u95B-4xzwA:undetectable | 4u95B-4xzwA:16.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zze | SUGAR BINDINGPROTEIN OF ABCTRANSPORTER SYSTEM (Bifidobacteriumanimalis) |
PF01547(SBP_bac_1) | 5 | PHE A 123GLY A 332ASP A 53PHE A 55ARG A 96 | None | 1.17A | 4u95B-4zzeA:undetectable | 4u95B-4zzeA:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cm6 | TRAP DICARBOXYLATETRANSPORTER-DCTPSUBUNIT (Pseudoalteromonasatlantica) |
PF03480(DctP) | 5 | GLU A 180ILE A 306ALA A 305VAL A 302PHE A 298 | None | 1.11A | 4u95B-5cm6A:undetectable | 4u95B-5cm6A:15.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5emi | CELL WALLHYDROLASE/AUTOLYSIN (Nostocpunctiforme) |
PF01520(Amidase_3) | 5 | SER A 570ASP A 444ILE A 443ALA A 474VAL A 473 | None | 1.16A | 4u95B-5emiA:undetectable | 4u95B-5emiA:10.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5eno | MULTIDRUG EFFLUXPUMP SUBUNITACRB,MULTIDRUGEFFLUX PUMP SUBUNITACRB (Escherichiacoli) |
PF00873(ACR_tran) | 6 | ASP A 276ILE A 277ALA A 279VAL A 612PHE A 615ARG A 620 | None | 0.97A | 4u95B-5enoA:43.5 | 4u95B-5enoA:73.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5eno | MULTIDRUG EFFLUXPUMP SUBUNITACRB,MULTIDRUGEFFLUX PUMP SUBUNITACRB (Escherichiacoli) |
PF00873(ACR_tran) | 5 | PHE A 178GLY A 179SER A 180GLU A 273ASN A 274 | None | 1.05A | 4u95B-5enoA:43.5 | 4u95B-5enoA:73.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5eno | MULTIDRUG EFFLUXPUMP SUBUNITACRB,MULTIDRUGEFFLUX PUMP SUBUNITACRB (Escherichiacoli) |
PF00873(ACR_tran) | 6 | SER A 48ASP A 276ILE A 277ALA A 279VAL A 612PHE A 615 | None | 1.02A | 4u95B-5enoA:43.5 | 4u95B-5enoA:73.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5eno | MULTIDRUG EFFLUXPUMP SUBUNITACRB,MULTIDRUGEFFLUX PUMP SUBUNITACRB (Escherichiacoli) |
PF00873(ACR_tran) | 6 | SER A 48GLU A 273ASP A 276ILE A 277ALA A 279VAL A 612 | None | 0.83A | 4u95B-5enoA:43.5 | 4u95B-5enoA:73.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5eno | MULTIDRUG EFFLUXPUMP SUBUNITACRB,MULTIDRUGEFFLUX PUMP SUBUNITACRB (Escherichiacoli) |
PF00873(ACR_tran) | 5 | SER A 48PHE A 178GLY A 179SER A 180GLU A 273 | None | 0.71A | 4u95B-5enoA:43.5 | 4u95B-5enoA:73.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f5o | NUCLEOPROTEIN (Marburgmarburgvirus) |
PF05505(Ebola_NP) | 5 | GLY A 45ASN A 43ASP A 40ALA A 115PHE A 99 | None | 1.13A | 4u95B-5f5oA:undetectable | 4u95B-5f5oA:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fzp | DISPASEAUTOLYSIS-INDUCINGPROTEIN (Streptomycesmobaraensis) |
no annotation | 5 | SER A 118GLY A 81SER A 82GLU A 99ALA A 78 | None | 1.16A | 4u95B-5fzpA:undetectable | 4u95B-5fzpA:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihs | ENDOGLUCANASE,GLYCOSIDE HYDROLASEFAMILY 5 PROTEIN (Cytophagahutchinsonii) |
PF00150(Cellulase) | 6 | SER A 55GLY A 193SER A 198GLU A 159ASN A 158ALA A 174 | None | 1.41A | 4u95B-5ihsA:undetectable | 4u95B-5ihsA:15.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ikj | CRYPTIC LOCIREGULATOR 2 (Schizosaccharomycespombe) |
PF10383(Clr2)PF16761(Clr2_transil) | 5 | PHE A 372GLY A 374ILE A 319ALA A 510VAL A 511 | None | 0.83A | 4u95B-5ikjA:undetectable | 4u95B-5ikjA:20.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjd | COLLAGEN TYPE IVALPHA-3-BINDINGPROTEIN (Homo sapiens) |
PF01852(START) | 5 | SER B 382ASN B 556ILE B 523ALA B 521VAL B 480 | NoneNonePEG B 601 ( 3.7A)PEG B 601 ( 3.9A)None | 1.14A | 4u95B-5jjdB:2.1 | 4u95B-5jjdB:13.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jvb | PHOSPHONATE ABCTRANSPORTER,PERIPLASMICPHOSPHONATE-BINDINGPROTEIN (Trichodesmiumerythraeum) |
no annotation | 5 | GLY A 170GLU A 109ILE A 122ALA A 124VAL A 155 | None | 1.01A | 4u95B-5jvbA:undetectable | 4u95B-5jvbA:15.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n6u | BETA-MANNOSIDASE (Dictyoglomusthermophilum) |
PF00703(Glyco_hydro_2)PF02837(Glyco_hydro_2_N) | 6 | PHE A 383GLY A 422SER A 467ASN A 426ILE A 446VAL A 450 | None | 1.43A | 4u95B-5n6uA:undetectable | 4u95B-5n6uA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ngj | TAIL TUBE PROTEIN (Escherichiavirus T5) |
no annotation | 5 | PHE A 255GLY A 257GLU A 260ASN A 234ILE A 237 | None | 1.16A | 4u95B-5ngjA:undetectable | 4u95B-5ngjA:6.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nva | PUTATIVESODIUM:SOLUTESYMPORTER (Proteusmirabilis) |
no annotation | 5 | GLY A 174ASP A 182ILE A 179VAL A 45ARG A 260 | None NA A 502 (-2.1A)NoneNone NA A 502 ( 4.5A) | 1.11A | 4u95B-5nvaA:1.7 | 4u95B-5nvaA:5.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oko | PHOSPHATIDYLINOSITOL3,4,5-TRISPHOSPHATE5-PHOSPHATASE 2 (Homo sapiens) |
PF03372(Exo_endo_phos) | 5 | SER A 716PHE A 605GLY A 606ALA A 543VAL A 544 | None | 1.15A | 4u95B-5okoA:undetectable | 4u95B-5okoA:17.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uqc | DIHYDROPYRIMIDINASE-RELATED PROTEIN 2 (Mus musculus) |
PF01979(Amidohydro_1) | 5 | SER A 282SER A 259GLU A 229ILE A 264ALA A 267 | None | 1.15A | 4u95B-5uqcA:undetectable | 4u95B-5uqcA:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vld | HISTIDINOLDEHYDROGENASE,CHLOROPLASTIC (Medicagotruncatula) |
PF00815(Histidinol_dh) | 5 | ASN A 320ASP A 318ILE A 322ALA A 293VAL A 292 | None | 1.15A | 4u95B-5vldA:undetectable | 4u95B-5vldA:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6aph | ADENOSYLHOMOCYSTEINASE (Elizabethkingiaanophelis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | SER A 360GLU A 24ILE A 95ALA A 96VAL A 102 | None | 1.15A | 4u95B-6aphA:undetectable | 4u95B-6aphA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ey4 | GLDM (Flavobacteriumjohnsoniae) |
no annotation | 6 | GLY A 370ASN A 354ILE A 356ALA A 358VAL A 386PHE A 348 | None | 1.42A | 4u95B-6ey4A:3.5 | 4u95B-6ey4A:5.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gbn | - (-) |
no annotation | 5 | SER A 358GLU A 22ILE A 93ALA A 94VAL A 100 | None | 1.14A | 4u95B-6gbnA:1.5 | 4u95B-6gbnA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gjt | - (-) |
no annotation | 5 | SER A 194ASP A 168ILE A 169ALA A 171VAL A 235 | None | 1.02A | 4u95B-6gjtA:undetectable | 4u95B-6gjtA:undetectable |