SIMILAR PATTERNS OF AMINO ACIDS FOR 4U8Y_B_MIYB1102_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bjn PHOSPHOSERINE
AMINOTRANSFERASE


(Escherichia
coli)
PF00266
(Aminotran_5)
5 GLU A 345
ILE A 338
ALA A 336
PHE A 302
VAL A 300
None
1.11A 4u8yB-1bjnA:
0.0
4u8yB-1bjnA:
16.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cby DELTA-ENDOTOXIN CYTB

(Bacillus
thuringiensis)
PF01338
(Bac_thur_toxin)
5 SER A  38
ASN A 238
ASP A 235
ILE A 236
PHE A  47
None
0.98A 4u8yB-1cbyA:
0.1
4u8yB-1cbyA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dj2 ADENYLOSUCCINATE
SYNTHETASE


(Arabidopsis
thaliana)
PF00709
(Adenylsucc_synt)
5 SER A  22
ASP A  46
ILE A  47
ALA A  49
VAL A  86
None
1.05A 4u8yB-1dj2A:
0.0
4u8yB-1dj2A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dj3 ADENYLOSUCCINATE
SYNTHETASE


(Triticum
aestivum)
PF00709
(Adenylsucc_synt)
5 SER A  21
ASP A  45
ILE A  46
ALA A  48
VAL A  85
None
1.03A 4u8yB-1dj3A:
0.0
4u8yB-1dj3A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8k ARSENITE OXIDASE

(Alcaligenes
faecalis)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
5 PHE A 752
GLY A 753
SER A 754
GLU A 747
ALA A 468
None
1.01A 4u8yB-1g8kA:
0.0
4u8yB-1g8kA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gri GROWTH FACTOR BOUND
PROTEIN 2


(Homo sapiens)
PF00017
(SH2)
PF00018
(SH3_1)
5 PHE A 167
GLY A 176
ILE A 183
ALA A 163
VAL A 210
None
1.13A 4u8yB-1griA:
0.0
4u8yB-1griA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gz0 HYPOTHETICAL
TRNA/RRNA
METHYLTRANSFERASE
YJFH


(Escherichia
coli)
PF00588
(SpoU_methylase)
PF08032
(SpoU_sub_bind)
5 GLY A   7
ALA A  72
PHE A  22
VAL A  25
ARG A  31
None
1.01A 4u8yB-1gz0A:
0.0
4u8yB-1gz0A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mab PROTEIN (F1-ATPASE
BETA CHAIN)


(Rattus
norvegicus)
PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N)
5 GLU B 100
ASN B  96
ALA B 216
PHE B 243
VAL B 182
None
1.15A 4u8yB-1mabB:
undetectable
4u8yB-1mabB:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tmh TRIOSEPHOSPHATE
ISOMERASE


(Escherichia
coli)
PF00121
(TIM)
5 GLU A 252
ASN A 249
ASP A 246
ILE A 247
VAL A 215
None
1.10A 4u8yB-1tmhA:
undetectable
4u8yB-1tmhA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ur4 GALACTANASE

(Bacillus
licheniformis)
PF07745
(Glyco_hydro_53)
5 GLY A 256
ASP A 227
ALA A 313
VAL A 259
PHE A 229
None
1.09A 4u8yB-1ur4A:
undetectable
4u8yB-1ur4A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wf7 ENIGMA HOMOLOGUE
PROTEIN


(Mus musculus)
PF00595
(PDZ)
5 SER A   8
ASN A  81
ASP A  57
ILE A  56
ALA A  61
None
0.99A 4u8yB-1wf7A:
undetectable
4u8yB-1wf7A:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zz3 HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE


(Alcaligenaceae
bacterium FB188)
PF00850
(Hist_deacetyl)
5 ASP A  69
ILE A  72
ALA A  75
VAL A 160
ARG A 112
None
1.11A 4u8yB-1zz3A:
0.2
4u8yB-1zz3A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c07 3-OXOACYL-(ACYL-CARR
IER PROTEIN)
REDUCTASE


(Plasmodium
falciparum)
PF13561
(adh_short_C2)
5 GLY A 202
ASN A 206
ILE A 200
ALA A 241
VAL A 297
None
1.12A 4u8yB-2c07A:
undetectable
4u8yB-2c07A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c47 CASEIN KINASE 1
GAMMA 2 ISOFORM


(Homo sapiens)
PF00069
(Pkinase)
5 GLU A  77
ILE A  74
ALA A  73
VAL A  72
PHE A  46
None
None
5ID  A1300 ( 3.8A)
None
None
0.96A 4u8yB-2c47A:
3.1
4u8yB-2c47A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c49 SUGAR KINASE MJ0406

(Methanocaldococcus
jannaschii)
PF00294
(PfkB)
5 SER A  86
ASP A  82
ILE A  83
ALA A  49
VAL A  50
None
1.08A 4u8yB-2c49A:
undetectable
4u8yB-2c49A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eo0 HYPOTHETICAL PROTEIN
ST1444


(Sulfurisphaera
tokodaii)
PF01870
(Hjc)
5 ASP A  45
ILE A  46
ALA A  48
PHE A  27
VAL A  29
None
1.08A 4u8yB-2eo0A:
undetectable
4u8yB-2eo0A:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j0r HEMIN TRANSPORT
PROTEIN HEMS


(Yersinia
enterocolitica)
PF05171
(HemS)
5 GLY A  79
GLU A  82
ASN A  95
ASP A 100
PHE A 256
None
0.93A 4u8yB-2j0rA:
undetectable
4u8yB-2j0rA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jir PERIPLASMIC NITRATE
REDUCTASE


(Desulfovibrio
desulfuricans)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4)
5 ASP A 215
ILE A 201
ALA A 203
PHE A 220
VAL A 218
None
None
None
MGD  A 812 (-4.7A)
None
1.13A 4u8yB-2jirA:
undetectable
4u8yB-2jirA:
22.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o8e DNA MISMATCH REPAIR
PROTEIN MSH6


(Homo sapiens)
PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III)
5 GLY B1216
ILE B1227
ALA B1228
PHE B1245
VAL B1231
None
1.13A 4u8yB-2o8eB:
2.4
4u8yB-2o8eB:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pq6 UDP-GLUCURONOSYL/UDP
-GLUCOSYLTRANSFERASE


(Medicago
truncatula)
PF00201
(UDPGT)
5 PHE A 302
GLY A 303
SER A 304
ILE A 330
PHE A 375
None
1.12A 4u8yB-2pq6A:
undetectable
4u8yB-2pq6A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyw UNCHARACTERIZED
PROTEIN


(Arabidopsis
thaliana)
PF01636
(APH)
5 SER A 391
ILE A 416
ALA A 415
PHE A 406
VAL A 412
None
1.08A 4u8yB-2pywA:
3.5
4u8yB-2pywA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qy6 UPF0209 PROTEIN YFCK

(Escherichia
coli)
PF05430
(Methyltransf_30)
5 GLY A  65
ASP A 198
ALA A 194
PHE A  80
VAL A  82
None
1.00A 4u8yB-2qy6A:
undetectable
4u8yB-2qy6A:
12.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wrz L-ARABINOSE-BINDING
PERIPLASMIC PROTEIN


(Escherichia
coli)
PF00532
(Peripla_BP_1)
5 PHE A  61
GLY A   6
GLU A  34
ILE A  38
VAL A  40
None
1.07A 4u8yB-2wrzA:
undetectable
4u8yB-2wrzA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yut PUTATIVE SHORT-CHAIN
OXIDOREDUCTASE


(Thermus
thermophilus)
PF00106
(adh_short)
5 GLY A  14
ILE A   5
ALA A  73
PHE A 119
VAL A  71
None
None
NAP  A 500 (-4.1A)
NAP  A 500 ( 4.4A)
None
1.10A 4u8yB-2yutA:
undetectable
4u8yB-2yutA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afl OLIGO ALGINATE LYASE

(Agrobacterium
fabrum)
PF07940
(Hepar_II_III)
PF16332
(DUF4962)
5 GLY A 362
ILE A 501
ALA A 353
PHE A 393
PHE A 498
None
1.15A 4u8yB-3aflA:
undetectable
4u8yB-3aflA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dui BETA-GALACTOSIDE-BIN
DING LECTIN


(Gallus gallus)
PF00337
(Gal-bind_lectin)
5 GLY A  22
ASP A 125
ILE A  24
ALA A  84
PHE A  80
None
1.05A 4u8yB-3duiA:
undetectable
4u8yB-3duiA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fj7 MAJOR ANTIGENIC
PEPTIDE PEB3


(Campylobacter
jejuni)
PF13531
(SBP_bac_11)
5 ASN A  23
ASP A  68
ILE A  69
PHE A 215
VAL A 217
None
1.12A 4u8yB-3fj7A:
undetectable
4u8yB-3fj7A:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04


(Sarcoptes
scabiei)
PF00089
(Trypsin)
5 SER A 107
ASP A  71
ILE A  56
ALA A  17
VAL A  18
None
1.01A 4u8yB-3h7oA:
undetectable
4u8yB-3h7oA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE


(Corynebacterium
diphtheriae)
no annotation 5 GLY A  34
SER A  33
GLU A  53
ILE A  75
ALA A  49
None
1.11A 4u8yB-3hm2A:
undetectable
4u8yB-3hm2A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iib PEPTIDASE M28

(Shewanella
amazonensis)
PF04389
(Peptidase_M28)
5 GLY A 176
SER A 175
ASP A 141
ALA A 184
PHE A 156
None
1.13A 4u8yB-3iibA:
undetectable
4u8yB-3iibA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l5k HALOACID
DEHALOGENASE-LIKE
HYDROLASE
DOMAIN-CONTAINING
PROTEIN 1A


(Homo sapiens)
PF13419
(HAD_2)
5 GLY A 180
GLU A 182
ASP A 153
ILE A 154
ALA A 112
None
1.13A 4u8yB-3l5kA:
undetectable
4u8yB-3l5kA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o07 PYRIDOXINE
BIOSYNTHESIS PROTEIN
SNZ1


(Saccharomyces
cerevisiae)
PF01680
(SOR_SNZ)
5 ASN A  71
ASP A  68
ILE A  69
ALA A  30
VAL A  24
None
1.14A 4u8yB-3o07A:
undetectable
4u8yB-3o07A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN


(Escherichia
coli)
PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5)
5 GLU B 633
ILE B 652
ALA B 650
PHE B 614
VAL B 662
None
0.95A 4u8yB-3pcoB:
undetectable
4u8yB-3pcoB:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pl5 PUTATIVE
UNCHARACTERIZED
PROTEIN


(Streptococcus
mutans)
PF02645
(DegV)
5 ASN A 237
ASP A 238
ALA A 234
PHE A 279
ARG A 211
None
None
PLM  A 702 ( 4.9A)
None
None
1.08A 4u8yB-3pl5A:
undetectable
4u8yB-3pl5A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qbo PHOSPHOSERINE
AMINOTRANSFERASE


(Yersinia pestis)
PF00266
(Aminotran_5)
5 GLU A 344
ILE A 337
ALA A 335
PHE A 301
VAL A 299
None
1.03A 4u8yB-3qboA:
undetectable
4u8yB-3qboA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qlt GLUTAMATE RECEPTOR,
IONOTROPIC KAINATE 2


(Rattus
norvegicus)
PF01094
(ANF_receptor)
5 PHE A 248
GLU A 254
ASN A 252
ILE A 250
PHE A 356
None
1.04A 4u8yB-3qltA:
undetectable
4u8yB-3qltA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qm2 PHOSPHOSERINE
AMINOTRANSFERASE


(Salmonella
enterica)
PF00266
(Aminotran_5)
5 GLU A 345
ILE A 338
ALA A 336
PHE A 302
VAL A 300
None
1.07A 4u8yB-3qm2A:
undetectable
4u8yB-3qm2A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sg1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1


(Bacillus
anthracis)
PF00275
(EPSP_synthase)
5 SER A 322
ASN A 356
ASP A 345
ILE A 346
VAL A 336
None
1.06A 4u8yB-3sg1A:
undetectable
4u8yB-3sg1A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqk PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE


(Francisella
tularensis)
PF00793
(DAHP_synth_1)
5 PHE A 158
GLU A  25
ASP A  30
ILE A  31
ARG A 129
None
1.12A 4u8yB-3tqkA:
undetectable
4u8yB-3tqkA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vpc PUTATIVE
ACETYLORNITHINE
DEACETYLASE


(Sulfurisphaera
tokodaii)
PF08443
(RimK)
5 GLU A 240
ASP A 237
ILE A 236
ALA A 225
VAL A 226
None
1.09A 4u8yB-3vpcA:
undetectable
4u8yB-3vpcA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vwo PEPTIDOGLYCAN
HYDROLASE FLGJ


(Sphingomonas
sp. A1)
PF01832
(Glucosaminidase)
6 GLY A 189
SER A 191
ALA A 182
PHE A 247
VAL A 179
ARG A 303
None
1.35A 4u8yB-3vwoA:
undetectable
4u8yB-3vwoA:
10.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9h ACRIFLAVINE
RESISTANCE PROTEIN B


(Escherichia
coli)
PF00873
(ACR_tran)
7 GLU A 273
ASP A 276
ILE A 277
ALA A 279
PHE A 610
VAL A 612
PHE A 615
None
0.85A 4u8yB-3w9hA:
59.0
4u8yB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9h ACRIFLAVINE
RESISTANCE PROTEIN B


(Escherichia
coli)
PF00873
(ACR_tran)
6 GLY A 179
GLU A 273
ALA A 279
PHE A 610
VAL A 612
PHE A 615
None
1.21A 4u8yB-3w9hA:
59.0
4u8yB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9h ACRIFLAVINE
RESISTANCE PROTEIN B


(Escherichia
coli)
PF00873
(ACR_tran)
6 GLY A 179
SER A 180
GLU A 273
ALA A 279
PHE A 610
VAL A 612
None
1.18A 4u8yB-3w9hA:
59.0
4u8yB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9i MULTIDRUG RESISTANCE
PROTEIN MEXB


(Pseudomonas
aeruginosa)
PF00873
(ACR_tran)
5 GLY A 179
SER A 180
ALA A 279
PHE A 610
ARG A 620
None
0.99A 4u8yB-3w9iA:
51.8
4u8yB-3w9iA:
69.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9i MULTIDRUG RESISTANCE
PROTEIN MEXB


(Pseudomonas
aeruginosa)
PF00873
(ACR_tran)
5 GLY A 179
SER A 180
ALA A 279
PHE A 610
PHE A 615
None
0.81A 4u8yB-3w9iA:
51.8
4u8yB-3w9iA:
69.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9i MULTIDRUG RESISTANCE
PROTEIN MEXB


(Pseudomonas
aeruginosa)
PF00873
(ACR_tran)
5 ILE A 277
ALA A 279
PHE A 610
VAL A 612
ARG A 620
None
0.91A 4u8yB-3w9iA:
51.8
4u8yB-3w9iA:
69.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9i MULTIDRUG RESISTANCE
PROTEIN MEXB


(Pseudomonas
aeruginosa)
PF00873
(ACR_tran)
5 ILE A 277
ALA A 279
PHE A 610
VAL A 612
PHE A 615
None
0.77A 4u8yB-3w9iA:
51.8
4u8yB-3w9iA:
69.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9i MULTIDRUG RESISTANCE
PROTEIN MEXB


(Pseudomonas
aeruginosa)
PF00873
(ACR_tran)
5 SER A 180
ALA A 279
PHE A 610
VAL A 612
ARG A 620
None
1.03A 4u8yB-3w9iA:
51.8
4u8yB-3w9iA:
69.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9i MULTIDRUG RESISTANCE
PROTEIN MEXB


(Pseudomonas
aeruginosa)
PF00873
(ACR_tran)
5 SER A 180
ALA A 279
PHE A 610
VAL A 612
PHE A 615
None
0.77A 4u8yB-3w9iA:
51.8
4u8yB-3w9iA:
69.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN


(Carboxydothermus
hydrogenoformans)
PF14574
(DUF4445)
5 GLY I 466
SER I 465
ASP I 469
ILE I 468
PHE I 486
None
0.83A 4u8yB-4c1nI:
undetectable
4u8yB-4c1nI:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cqm CARBONYL REDUCTASE
FAMILY MEMBER 4


(Homo sapiens)
PF13561
(adh_short_C2)
6 GLY B 138
SER B 149
ASN B 142
ILE B 136
ALA B 177
VAL B 228
None
1.13A 4u8yB-4cqmB:
undetectable
4u8yB-4cqmB:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d1d HYDANTOIN TRANSPORT
PROTEIN


(Microbacterium
liquefaciens)
PF02133
(Transp_cyt_pur)
6 GLY A 271
SER A 274
ASN A 282
ILE A  47
ALA A  48
PHE A 216
None
None
None
None
5ND  A1468 ( 3.4A)
5ND  A1468 ( 4.4A)
1.47A 4u8yB-4d1dA:
1.8
4u8yB-4d1dA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0a PROTEIN WNT-8

(Xenopus laevis)
PF00110
(wnt)
5 ASN B 207
ASP B 204
ILE B 205
ALA B 172
VAL B 173
None
0.94A 4u8yB-4f0aB:
2.8
4u8yB-4f0aB:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdg MINICHROMOSOME
MAINTENANCE PROTEIN
MCM


(Sulfolobus
solfataricus)
no annotation 5 SER B 368
ASP B 404
ILE B 403
ALA B 401
VAL B 443
None
1.06A 4u8yB-4fdgB:
3.3
4u8yB-4fdgB:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fid G PROTEIN ALPHA
SUBUNIT


(Entamoeba
histolytica)
PF00503
(G-alpha)
5 GLY A  30
SER A  31
GLU A 230
ASP A 237
ILE A 238
None
1.11A 4u8yB-4fidA:
undetectable
4u8yB-4fidA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fn6 THIAMINASE-2

(Staphylococcus
aureus)
PF03070
(TENA_THI-4)
5 GLU A 179
ASN A 176
ASP A 173
ILE A 174
PHE A  51
None
1.07A 4u8yB-4fn6A:
undetectable
4u8yB-4fn6A:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fus RTX TOXINS AND
RELATED CA2+-BINDING
PROTEIN


(Hahella
chejuensis)
PF02011
(Glyco_hydro_48)
5 PHE A 428
GLY A 430
ASP A 302
ALA A 408
VAL A 353
None
None
None
None
OHI  A 352 ( 3.1A)
1.10A 4u8yB-4fusA:
undetectable
4u8yB-4fusA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fyu THIOREDOXIN

(Wuchereria
bancrofti)
PF13905
(Thioredoxin_8)
5 GLY A  20
SER A  21
ASN A   7
ILE A   8
VAL A  89
None
1.12A 4u8yB-4fyuA:
undetectable
4u8yB-4fyuA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g9k ROTENONE-INSENSITIVE
NADH-UBIQUINONE
OXIDOREDUCTASE


(Saccharomyces
cerevisiae)
PF07992
(Pyr_redox_2)
5 GLY A  60
SER A  61
ILE A  82
ALA A 129
VAL A 139
GLY  A  60 (-0.0A)
SER  A  61 (-0.0A)
ILE  A  82 (-0.7A)
ALA  A 129 (-0.0A)
VAL  A 139 ( 0.6A)
0.90A 4u8yB-4g9kA:
undetectable
4u8yB-4g9kA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 13


(Thermus
thermophilus)
PF00361
(Proton_antipo_M)
5 GLY M 237
ALA M 297
PHE M 301
VAL M 300
PHE M 242
None
1.13A 4u8yB-4heaM:
undetectable
4u8yB-4heaM:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwt THREONINE--TRNA
LIGASE, CYTOPLASMIC


(Homo sapiens)
PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon)
5 PHE A 559
GLU A 564
ASN A 530
ASP A 578
ILE A 577
None
None
None
1B2  A 802 (-3.7A)
None
1.14A 4u8yB-4hwtA:
undetectable
4u8yB-4hwtA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jdn VIRULENCE PLASMID
PROTEIN PGP3-D


(Chlamydia
trachomatis)
PF05475
(Chlam_vir)
5 SER A 194
ASP A 168
ILE A 169
ALA A 171
VAL A 235
None
1.08A 4u8yB-4jdnA:
undetectable
4u8yB-4jdnA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jdo VIRULENCE PLASMID
PROTEIN PGP3-D


(Chlamydia
trachomatis)
PF05475
(Chlam_vir)
5 SER A 194
ASP A 168
ILE A 169
ALA A 171
VAL A 235
None
1.08A 4u8yB-4jdoA:
undetectable
4u8yB-4jdoA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kq9 RIBOSE ABC
TRANSPORTER,
SUBSTRATE BINDING
PROTEIN


(Conexibacter
woesei)
PF13407
(Peripla_BP_4)
5 GLY A 150
SER A 151
ILE A 294
ALA A 295
VAL A 298
None
GOL  A 501 ( 4.9A)
None
None
None
1.05A 4u8yB-4kq9A:
undetectable
4u8yB-4kq9A:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ll1 THIOREDOXIN-INTERACT
ING PROTEIN


(Homo sapiens)
PF00339
(Arrestin_N)
PF02752
(Arrestin_C)
5 GLY A 102
ILE A  46
ALA A  48
PHE A 143
VAL A 125
None
1.12A 4u8yB-4ll1A:
undetectable
4u8yB-4ll1A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nt4 GILGAMESH, ISOFORM I

(Drosophila
melanogaster)
PF00069
(Pkinase)
5 GLU A  74
ILE A  71
ALA A  70
VAL A  69
PHE A  43
None
1.01A 4u8yB-4nt4A:
undetectable
4u8yB-4nt4A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qko PYOCIN-S2
PYOCIN-S2 IMMUNITY
PROTEIN


(Pseudomonas
aeruginosa)
PF01320
(Colicin_Pyocin)
no annotation
5 GLY B 628
ASP A  19
ILE A  20
VAL A  38
PHE A  41
None
1.07A 4u8yB-4qkoB:
undetectable
4u8yB-4qkoB:
7.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tkd HOLLIDAY JUNCTION
RESOLVASE HJC


(Sulfolobus
solfataricus)
PF01870
(Hjc)
5 ASP A  42
ILE A  43
ALA A  45
PHE A  24
VAL A  26
None
1.09A 4u8yB-4tkdA:
undetectable
4u8yB-4tkdA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3t PENICILLIN-BINDING
PROTEIN 2


(Neisseria
gonorrhoeae)
PF00905
(Transpeptidase)
5 PHE A 315
SER A 419
ILE A 317
ALA A 318
PHE A 462
None
1.07A 4u8yB-4u3tA:
undetectable
4u8yB-4u3tA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3t PENICILLIN-BINDING
PROTEIN 2


(Neisseria
gonorrhoeae)
PF00905
(Transpeptidase)
5 PHE A 315
SER A 419
ILE A 317
ALA A 318
VAL A 470
None
1.12A 4u8yB-4u3tA:
undetectable
4u8yB-4u3tA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbd BSHC

(Bacillus
subtilis)
PF10079
(BshC)
5 ASN A  12
ILE A 354
ALA A 349
PHE A 347
VAL A 374
None
1.03A 4u8yB-4wbdA:
3.5
4u8yB-4wbdA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbd BSHC

(Bacillus
subtilis)
PF10079
(BshC)
5 GLY A 352
ASN A  12
ALA A 349
PHE A 347
VAL A 374
CIT  A 602 (-3.5A)
None
None
None
None
1.08A 4u8yB-4wbdA:
3.5
4u8yB-4wbdA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wyu PROTEIN SCRIBBLE
HOMOLOG


(Homo sapiens)
PF00595
(PDZ)
5 GLY A  30
SER A  36
ILE A  28
ALA A  84
VAL A  85
None
1.06A 4u8yB-4wyuA:
undetectable
4u8yB-4wyuA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhg SIMILAR TO
UNIPROT|P29295
SACCHAROMYCES
CEREVISIAE YPL204W
HRR25


([Candida]
glabrata)
PF00069
(Pkinase)
5 GLU A  40
ILE A  37
ALA A  36
VAL A  35
PHE A   9
None
None
ADP  A 501 ( 3.7A)
None
None
1.04A 4u8yB-4xhgA:
undetectable
4u8yB-4xhgA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhl CASEIN KINASE I
HOMOLOG HRR25


(Saccharomyces
cerevisiae)
PF00069
(Pkinase)
5 GLU A  40
ILE A  37
ALA A  36
VAL A  35
PHE A   9
None
None
CKI  A 401 (-3.3A)
None
None
0.95A 4u8yB-4xhlA:
undetectable
4u8yB-4xhlA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xup ENDO-1,4-BETA-XYLANA
SE C


(Paenibacillus
barcinonensis)
PF02018
(CBM_4_9)
5 GLU A 195
ALA A 176
PHE A 174
VAL A 327
PHE A 238
None
0.85A 4u8yB-4xupA:
undetectable
4u8yB-4xupA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xut ENDO-1,4-BETA-XYLANA
SE C


(Paenibacillus
barcinonensis)
PF02018
(CBM_4_9)
5 GLU A 195
ALA A 176
PHE A 174
VAL A 327
PHE A 238
None
0.90A 4u8yB-4xutA:
undetectable
4u8yB-4xutA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z2q LECTIN

(Athelia rolfsii)
PF07367
(FB_lectin)
5 GLU A  61
ASN A 116
ILE A  78
ALA A  65
PHE A  67
None
1.14A 4u8yB-4z2qA:
undetectable
4u8yB-4z2qA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bq2 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE


(Pseudomonas
aeruginosa)
PF00275
(EPSP_synthase)
5 GLY A 401
ILE A 398
ALA A 377
VAL A 380
ARG A 418
None
1.15A 4u8yB-5bq2A:
undetectable
4u8yB-5bq2A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c5g SPHERULIN-4

(Aspergillus
clavatus)
PF12138
(Spherulin4)
5 PHE A 221
ILE A 278
ALA A 275
PHE A 237
VAL A 271
None
1.08A 4u8yB-5c5gA:
undetectable
4u8yB-5c5gA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cdf ATP SYNTHASE SUBUNIT
BETA


(Paracoccus
denitrificans)
PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N)
5 GLU E  95
ASN E  91
ALA E 212
PHE E 239
VAL E 177
None
1.05A 4u8yB-5cdfE:
undetectable
4u8yB-5cdfE:
19.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eno MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB


(Escherichia
coli)
PF00873
(ACR_tran)
6 ASP A 276
ILE A 277
ALA A 279
PHE A 610
VAL A 612
PHE A 615
None
0.76A 4u8yB-5enoA:
43.9
4u8yB-5enoA:
73.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eno MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB


(Escherichia
coli)
PF00873
(ACR_tran)
5 GLU A 273
ASN A 274
ASP A 276
ALA A 279
PHE A 610
None
0.96A 4u8yB-5enoA:
43.9
4u8yB-5enoA:
73.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eno MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB


(Escherichia
coli)
PF00873
(ACR_tran)
6 GLU A 273
ASP A 276
ILE A 277
ALA A 279
PHE A 610
VAL A 612
None
0.85A 4u8yB-5enoA:
43.9
4u8yB-5enoA:
73.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eno MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB


(Escherichia
coli)
PF00873
(ACR_tran)
6 GLY A 179
SER A 180
GLU A 273
ASN A 274
ALA A 279
PHE A 610
None
1.38A 4u8yB-5enoA:
43.9
4u8yB-5enoA:
73.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eno MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB


(Escherichia
coli)
PF00873
(ACR_tran)
6 ILE A 277
ALA A 279
PHE A 610
VAL A 612
PHE A 615
ARG A 620
None
0.90A 4u8yB-5enoA:
43.9
4u8yB-5enoA:
73.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gl9 BETA-LACTAMASE

(Burkholderia
thailandensis)
PF13354
(Beta-lactamase2)
5 GLY A 224
ASP A 276
ILE A 279
ALA A 282
PHE A  47
None
1.13A 4u8yB-5gl9A:
undetectable
4u8yB-5gl9A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikj CRYPTIC LOCI
REGULATOR 2


(Schizosaccharomyces
pombe)
PF10383
(Clr2)
PF16761
(Clr2_transil)
5 PHE A 372
GLY A 374
ILE A 319
ALA A 510
VAL A 511
None
0.82A 4u8yB-5ikjA:
undetectable
4u8yB-5ikjA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ju6 BETA-GLUCOSIDASE

(Rasamsonia
emersonii)
PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like)
5 GLY A 284
SER A 283
ILE A 322
ALA A 316
VAL A 317
NAG  A 918 (-3.1A)
MAN  A 922 ( 4.6A)
None
NAG  A 917 ( 3.9A)
None
1.12A 4u8yB-5ju6A:
undetectable
4u8yB-5ju6A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jvb PHOSPHONATE ABC
TRANSPORTER,
PERIPLASMIC
PHOSPHONATE-BINDING
PROTEIN


(Trichodesmium
erythraeum)
no annotation 5 GLY A 170
GLU A 109
ILE A 122
ALA A 124
VAL A 155
None
0.98A 4u8yB-5jvbA:
undetectable
4u8yB-5jvbA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksh PENICILLIN-BINDING
PROTEIN 2


(Neisseria
gonorrhoeae)
PF00905
(Transpeptidase)
PF03717
(PBP_dimer)
6 PHE A 315
SER A 419
ILE A 317
ALA A 318
PHE A 462
VAL A 470
None
1.28A 4u8yB-5kshA:
undetectable
4u8yB-5kshA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6u BETA-MANNOSIDASE

(Dictyoglomus
thermophilum)
PF00703
(Glyco_hydro_2)
PF02837
(Glyco_hydro_2_N)
6 PHE A 383
GLY A 422
SER A 467
ASN A 426
ILE A 446
VAL A 450
None
1.41A 4u8yB-5n6uA:
undetectable
4u8yB-5n6uA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o7e COLH PROTEIN

(Hathewaya
histolytica)
no annotation 5 ASN A 573
ASP A 572
ILE A 575
PHE A 544
VAL A 527
None
1.10A 4u8yB-5o7eA:
2.9
4u8yB-5o7eA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xqo PCRGLX PROTEIN

(Penicillium
chrysogenum)
no annotation 5 GLU A 587
ASN A 902
ASP A 903
ILE A 904
PHE A 544
ADA  A1004 ( 3.7A)
RAM  A1003 ( 4.1A)
None
None
None
1.09A 4u8yB-5xqoA:
undetectable
4u8yB-5xqoA:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cn1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE


(Pseudomonas
putida)
no annotation 5 GLY A 401
ILE A 398
ALA A 377
VAL A 380
ARG A 418
None
1.09A 4u8yB-6cn1A:
undetectable
4u8yB-6cn1A:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d0s TBC1 DOMAIN FAMILY
MEMBER 22B


(Homo sapiens)
no annotation 5 GLY A 483
GLU A 480
ALA A 489
PHE A 440
VAL A 444
None
1.08A 4u8yB-6d0sA:
undetectable
4u8yB-6d0sA:
5.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ey4 GLDM

(Flavobacterium
johnsoniae)
no annotation 6 GLY A 370
ASN A 354
ILE A 356
ALA A 358
VAL A 386
PHE A 348
None
1.41A 4u8yB-6ey4A:
4.8
4u8yB-6ey4A:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fkh ATP SYNTHASE SUBUNIT
BETA, CHLOROPLASTIC


(Spinacia
oleracea)
no annotation 5 GLU D 116
ASN D 112
ALA D 233
PHE D 260
VAL D 198
None
1.14A 4u8yB-6fkhD:
undetectable
4u8yB-6fkhD:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gjt -

(-)
no annotation 5 SER A 194
ASP A 168
ILE A 169
ALA A 171
VAL A 235
None
1.03A 4u8yB-6gjtA:
undetectable
4u8yB-6gjtA:
undetectable