SIMILAR PATTERNS OF AMINO ACIDS FOR 4U8Y_B_MIYB1102_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bjn | PHOSPHOSERINEAMINOTRANSFERASE (Escherichiacoli) |
PF00266(Aminotran_5) | 5 | GLU A 345ILE A 338ALA A 336PHE A 302VAL A 300 | None | 1.11A | 4u8yB-1bjnA:0.0 | 4u8yB-1bjnA:16.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cby | DELTA-ENDOTOXIN CYTB (Bacillusthuringiensis) |
PF01338(Bac_thur_toxin) | 5 | SER A 38ASN A 238ASP A 235ILE A 236PHE A 47 | None | 0.98A | 4u8yB-1cbyA:0.1 | 4u8yB-1cbyA:13.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dj2 | ADENYLOSUCCINATESYNTHETASE (Arabidopsisthaliana) |
PF00709(Adenylsucc_synt) | 5 | SER A 22ASP A 46ILE A 47ALA A 49VAL A 86 | None | 1.05A | 4u8yB-1dj2A:0.0 | 4u8yB-1dj2A:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dj3 | ADENYLOSUCCINATESYNTHETASE (Triticumaestivum) |
PF00709(Adenylsucc_synt) | 5 | SER A 21ASP A 45ILE A 46ALA A 48VAL A 85 | None | 1.03A | 4u8yB-1dj3A:0.0 | 4u8yB-1dj3A:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g8k | ARSENITE OXIDASE (Alcaligenesfaecalis) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | PHE A 752GLY A 753SER A 754GLU A 747ALA A 468 | None | 1.01A | 4u8yB-1g8kA:0.0 | 4u8yB-1g8kA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gri | GROWTH FACTOR BOUNDPROTEIN 2 (Homo sapiens) |
PF00017(SH2)PF00018(SH3_1) | 5 | PHE A 167GLY A 176ILE A 183ALA A 163VAL A 210 | None | 1.13A | 4u8yB-1griA:0.0 | 4u8yB-1griA:11.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gz0 | HYPOTHETICALTRNA/RRNAMETHYLTRANSFERASEYJFH (Escherichiacoli) |
PF00588(SpoU_methylase)PF08032(SpoU_sub_bind) | 5 | GLY A 7ALA A 72PHE A 22VAL A 25ARG A 31 | None | 1.01A | 4u8yB-1gz0A:0.0 | 4u8yB-1gz0A:13.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mab | PROTEIN (F1-ATPASEBETA CHAIN) (Rattusnorvegicus) |
PF00006(ATP-synt_ab)PF02874(ATP-synt_ab_N) | 5 | GLU B 100ASN B 96ALA B 216PHE B 243VAL B 182 | None | 1.15A | 4u8yB-1mabB:undetectable | 4u8yB-1mabB:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tmh | TRIOSEPHOSPHATEISOMERASE (Escherichiacoli) |
PF00121(TIM) | 5 | GLU A 252ASN A 249ASP A 246ILE A 247VAL A 215 | None | 1.10A | 4u8yB-1tmhA:undetectable | 4u8yB-1tmhA:13.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ur4 | GALACTANASE (Bacilluslicheniformis) |
PF07745(Glyco_hydro_53) | 5 | GLY A 256ASP A 227ALA A 313VAL A 259PHE A 229 | None | 1.09A | 4u8yB-1ur4A:undetectable | 4u8yB-1ur4A:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wf7 | ENIGMA HOMOLOGUEPROTEIN (Mus musculus) |
PF00595(PDZ) | 5 | SER A 8ASN A 81ASP A 57ILE A 56ALA A 61 | None | 0.99A | 4u8yB-1wf7A:undetectable | 4u8yB-1wf7A:6.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zz3 | HISTONEDEACETYLASE-LIKEAMIDOHYDROLASE (Alcaligenaceaebacterium FB188) |
PF00850(Hist_deacetyl) | 5 | ASP A 69ILE A 72ALA A 75VAL A 160ARG A 112 | None | 1.11A | 4u8yB-1zz3A:0.2 | 4u8yB-1zz3A:16.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c07 | 3-OXOACYL-(ACYL-CARRIER PROTEIN)REDUCTASE (Plasmodiumfalciparum) |
PF13561(adh_short_C2) | 5 | GLY A 202ASN A 206ILE A 200ALA A 241VAL A 297 | None | 1.12A | 4u8yB-2c07A:undetectable | 4u8yB-2c07A:12.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c47 | CASEIN KINASE 1GAMMA 2 ISOFORM (Homo sapiens) |
PF00069(Pkinase) | 5 | GLU A 77ILE A 74ALA A 73VAL A 72PHE A 46 | NoneNone5ID A1300 ( 3.8A)NoneNone | 0.96A | 4u8yB-2c47A:3.1 | 4u8yB-2c47A:14.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c49 | SUGAR KINASE MJ0406 (Methanocaldococcusjannaschii) |
PF00294(PfkB) | 5 | SER A 86ASP A 82ILE A 83ALA A 49VAL A 50 | None | 1.08A | 4u8yB-2c49A:undetectable | 4u8yB-2c49A:15.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eo0 | HYPOTHETICAL PROTEINST1444 (Sulfurisphaeratokodaii) |
PF01870(Hjc) | 5 | ASP A 45ILE A 46ALA A 48PHE A 27VAL A 29 | None | 1.08A | 4u8yB-2eo0A:undetectable | 4u8yB-2eo0A:9.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j0r | HEMIN TRANSPORTPROTEIN HEMS (Yersiniaenterocolitica) |
PF05171(HemS) | 5 | GLY A 79GLU A 82ASN A 95ASP A 100PHE A 256 | None | 0.93A | 4u8yB-2j0rA:undetectable | 4u8yB-2j0rA:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jir | PERIPLASMIC NITRATEREDUCTASE (Desulfovibriodesulfuricans) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 5 | ASP A 215ILE A 201ALA A 203PHE A 220VAL A 218 | NoneNoneNoneMGD A 812 (-4.7A)None | 1.13A | 4u8yB-2jirA:undetectable | 4u8yB-2jirA:22.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o8e | DNA MISMATCH REPAIRPROTEIN MSH6 (Homo sapiens) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 5 | GLY B1216ILE B1227ALA B1228PHE B1245VAL B1231 | None | 1.13A | 4u8yB-2o8eB:2.4 | 4u8yB-2o8eB:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pq6 | UDP-GLUCURONOSYL/UDP-GLUCOSYLTRANSFERASE (Medicagotruncatula) |
PF00201(UDPGT) | 5 | PHE A 302GLY A 303SER A 304ILE A 330PHE A 375 | None | 1.12A | 4u8yB-2pq6A:undetectable | 4u8yB-2pq6A:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pyw | UNCHARACTERIZEDPROTEIN (Arabidopsisthaliana) |
PF01636(APH) | 5 | SER A 391ILE A 416ALA A 415PHE A 406VAL A 412 | None | 1.08A | 4u8yB-2pywA:3.5 | 4u8yB-2pywA:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qy6 | UPF0209 PROTEIN YFCK (Escherichiacoli) |
PF05430(Methyltransf_30) | 5 | GLY A 65ASP A 198ALA A 194PHE A 80VAL A 82 | None | 1.00A | 4u8yB-2qy6A:undetectable | 4u8yB-2qy6A:12.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wrz | L-ARABINOSE-BINDINGPERIPLASMIC PROTEIN (Escherichiacoli) |
PF00532(Peripla_BP_1) | 5 | PHE A 61GLY A 6GLU A 34ILE A 38VAL A 40 | None | 1.07A | 4u8yB-2wrzA:undetectable | 4u8yB-2wrzA:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yut | PUTATIVE SHORT-CHAINOXIDOREDUCTASE (Thermusthermophilus) |
PF00106(adh_short) | 5 | GLY A 14ILE A 5ALA A 73PHE A 119VAL A 71 | NoneNoneNAP A 500 (-4.1A)NAP A 500 ( 4.4A)None | 1.10A | 4u8yB-2yutA:undetectable | 4u8yB-2yutA:12.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3afl | OLIGO ALGINATE LYASE (Agrobacteriumfabrum) |
PF07940(Hepar_II_III)PF16332(DUF4962) | 5 | GLY A 362ILE A 501ALA A 353PHE A 393PHE A 498 | None | 1.15A | 4u8yB-3aflA:undetectable | 4u8yB-3aflA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dui | BETA-GALACTOSIDE-BINDING LECTIN (Gallus gallus) |
PF00337(Gal-bind_lectin) | 5 | GLY A 22ASP A 125ILE A 24ALA A 84PHE A 80 | None | 1.05A | 4u8yB-3duiA:undetectable | 4u8yB-3duiA:8.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fj7 | MAJOR ANTIGENICPEPTIDE PEB3 (Campylobacterjejuni) |
PF13531(SBP_bac_11) | 5 | ASN A 23ASP A 68ILE A 69PHE A 215VAL A 217 | None | 1.12A | 4u8yB-3fj7A:undetectable | 4u8yB-3fj7A:12.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7o | GROUP 3 ALLERGENSMIPP-S YV6023A04 (Sarcoptesscabiei) |
PF00089(Trypsin) | 5 | SER A 107ASP A 71ILE A 56ALA A 17VAL A 18 | None | 1.01A | 4u8yB-3h7oA:undetectable | 4u8yB-3h7oA:11.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hm2 | PRECORRIN-6YC5,15-METHYLTRANSFERASE (Corynebacteriumdiphtheriae) |
no annotation | 5 | GLY A 34SER A 33GLU A 53ILE A 75ALA A 49 | None | 1.11A | 4u8yB-3hm2A:undetectable | 4u8yB-3hm2A:11.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iib | PEPTIDASE M28 (Shewanellaamazonensis) |
PF04389(Peptidase_M28) | 5 | GLY A 176SER A 175ASP A 141ALA A 184PHE A 156 | None | 1.13A | 4u8yB-3iibA:undetectable | 4u8yB-3iibA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l5k | HALOACIDDEHALOGENASE-LIKEHYDROLASEDOMAIN-CONTAININGPROTEIN 1A (Homo sapiens) |
PF13419(HAD_2) | 5 | GLY A 180GLU A 182ASP A 153ILE A 154ALA A 112 | None | 1.13A | 4u8yB-3l5kA:undetectable | 4u8yB-3l5kA:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o07 | PYRIDOXINEBIOSYNTHESIS PROTEINSNZ1 (Saccharomycescerevisiae) |
PF01680(SOR_SNZ) | 5 | ASN A 71ASP A 68ILE A 69ALA A 30VAL A 24 | None | 1.14A | 4u8yB-3o07A:undetectable | 4u8yB-3o07A:13.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pco | PHENYLALANYL-TRNASYNTHETASE, BETACHAIN (Escherichiacoli) |
PF01588(tRNA_bind)PF03147(FDX-ACB)PF03483(B3_4)PF03484(B5) | 5 | GLU B 633ILE B 652ALA B 650PHE B 614VAL B 662 | None | 0.95A | 4u8yB-3pcoB:undetectable | 4u8yB-3pcoB:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pl5 | PUTATIVEUNCHARACTERIZEDPROTEIN (Streptococcusmutans) |
PF02645(DegV) | 5 | ASN A 237ASP A 238ALA A 234PHE A 279ARG A 211 | NoneNonePLM A 702 ( 4.9A)NoneNone | 1.08A | 4u8yB-3pl5A:undetectable | 4u8yB-3pl5A:16.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qbo | PHOSPHOSERINEAMINOTRANSFERASE (Yersinia pestis) |
PF00266(Aminotran_5) | 5 | GLU A 344ILE A 337ALA A 335PHE A 301VAL A 299 | None | 1.03A | 4u8yB-3qboA:undetectable | 4u8yB-3qboA:16.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qlt | GLUTAMATE RECEPTOR,IONOTROPIC KAINATE 2 (Rattusnorvegicus) |
PF01094(ANF_receptor) | 5 | PHE A 248GLU A 254ASN A 252ILE A 250PHE A 356 | None | 1.04A | 4u8yB-3qltA:undetectable | 4u8yB-3qltA:16.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qm2 | PHOSPHOSERINEAMINOTRANSFERASE (Salmonellaenterica) |
PF00266(Aminotran_5) | 5 | GLU A 345ILE A 338ALA A 336PHE A 302VAL A 300 | None | 1.07A | 4u8yB-3qm2A:undetectable | 4u8yB-3qm2A:16.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sg1 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE 1 (Bacillusanthracis) |
PF00275(EPSP_synthase) | 5 | SER A 322ASN A 356ASP A 345ILE A 346VAL A 336 | None | 1.06A | 4u8yB-3sg1A:undetectable | 4u8yB-3sg1A:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqk | PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATEALDOLASE (Francisellatularensis) |
PF00793(DAHP_synth_1) | 5 | PHE A 158GLU A 25ASP A 30ILE A 31ARG A 129 | None | 1.12A | 4u8yB-3tqkA:undetectable | 4u8yB-3tqkA:15.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vpc | PUTATIVEACETYLORNITHINEDEACETYLASE (Sulfurisphaeratokodaii) |
PF08443(RimK) | 5 | GLU A 240ASP A 237ILE A 236ALA A 225VAL A 226 | None | 1.09A | 4u8yB-3vpcA:undetectable | 4u8yB-3vpcA:14.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vwo | PEPTIDOGLYCANHYDROLASE FLGJ (Sphingomonassp. A1) |
PF01832(Glucosaminidase) | 6 | GLY A 189SER A 191ALA A 182PHE A 247VAL A 179ARG A 303 | None | 1.35A | 4u8yB-3vwoA:undetectable | 4u8yB-3vwoA:10.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w9h | ACRIFLAVINERESISTANCE PROTEIN B (Escherichiacoli) |
PF00873(ACR_tran) | 7 | GLU A 273ASP A 276ILE A 277ALA A 279PHE A 610VAL A 612PHE A 615 | None | 0.85A | 4u8yB-3w9hA:59.0 | 4u8yB-3w9hA:99.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w9h | ACRIFLAVINERESISTANCE PROTEIN B (Escherichiacoli) |
PF00873(ACR_tran) | 6 | GLY A 179GLU A 273ALA A 279PHE A 610VAL A 612PHE A 615 | None | 1.21A | 4u8yB-3w9hA:59.0 | 4u8yB-3w9hA:99.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w9h | ACRIFLAVINERESISTANCE PROTEIN B (Escherichiacoli) |
PF00873(ACR_tran) | 6 | GLY A 179SER A 180GLU A 273ALA A 279PHE A 610VAL A 612 | None | 1.18A | 4u8yB-3w9hA:59.0 | 4u8yB-3w9hA:99.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w9i | MULTIDRUG RESISTANCEPROTEIN MEXB (Pseudomonasaeruginosa) |
PF00873(ACR_tran) | 5 | GLY A 179SER A 180ALA A 279PHE A 610ARG A 620 | None | 0.99A | 4u8yB-3w9iA:51.8 | 4u8yB-3w9iA:69.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w9i | MULTIDRUG RESISTANCEPROTEIN MEXB (Pseudomonasaeruginosa) |
PF00873(ACR_tran) | 5 | GLY A 179SER A 180ALA A 279PHE A 610PHE A 615 | None | 0.81A | 4u8yB-3w9iA:51.8 | 4u8yB-3w9iA:69.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w9i | MULTIDRUG RESISTANCEPROTEIN MEXB (Pseudomonasaeruginosa) |
PF00873(ACR_tran) | 5 | ILE A 277ALA A 279PHE A 610VAL A 612ARG A 620 | None | 0.91A | 4u8yB-3w9iA:51.8 | 4u8yB-3w9iA:69.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w9i | MULTIDRUG RESISTANCEPROTEIN MEXB (Pseudomonasaeruginosa) |
PF00873(ACR_tran) | 5 | ILE A 277ALA A 279PHE A 610VAL A 612PHE A 615 | None | 0.77A | 4u8yB-3w9iA:51.8 | 4u8yB-3w9iA:69.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w9i | MULTIDRUG RESISTANCEPROTEIN MEXB (Pseudomonasaeruginosa) |
PF00873(ACR_tran) | 5 | SER A 180ALA A 279PHE A 610VAL A 612ARG A 620 | None | 1.03A | 4u8yB-3w9iA:51.8 | 4u8yB-3w9iA:69.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3w9i | MULTIDRUG RESISTANCEPROTEIN MEXB (Pseudomonasaeruginosa) |
PF00873(ACR_tran) | 5 | SER A 180ALA A 279PHE A 610VAL A 612PHE A 615 | None | 0.77A | 4u8yB-3w9iA:51.8 | 4u8yB-3w9iA:69.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c1n | IRON-SULFUR CLUSTERBINDING PROTEIN (Carboxydothermushydrogenoformans) |
PF14574(DUF4445) | 5 | GLY I 466SER I 465ASP I 469ILE I 468PHE I 486 | None | 0.83A | 4u8yB-4c1nI:undetectable | 4u8yB-4c1nI:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cqm | CARBONYL REDUCTASEFAMILY MEMBER 4 (Homo sapiens) |
PF13561(adh_short_C2) | 6 | GLY B 138SER B 149ASN B 142ILE B 136ALA B 177VAL B 228 | None | 1.13A | 4u8yB-4cqmB:undetectable | 4u8yB-4cqmB:13.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d1d | HYDANTOIN TRANSPORTPROTEIN (Microbacteriumliquefaciens) |
PF02133(Transp_cyt_pur) | 6 | GLY A 271SER A 274ASN A 282ILE A 47ALA A 48PHE A 216 | NoneNoneNoneNone5ND A1468 ( 3.4A)5ND A1468 ( 4.4A) | 1.47A | 4u8yB-4d1dA:1.8 | 4u8yB-4d1dA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0a | PROTEIN WNT-8 (Xenopus laevis) |
PF00110(wnt) | 5 | ASN B 207ASP B 204ILE B 205ALA B 172VAL B 173 | None | 0.94A | 4u8yB-4f0aB:2.8 | 4u8yB-4f0aB:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdg | MINICHROMOSOMEMAINTENANCE PROTEINMCM (Sulfolobussolfataricus) |
no annotation | 5 | SER B 368ASP B 404ILE B 403ALA B 401VAL B 443 | None | 1.06A | 4u8yB-4fdgB:3.3 | 4u8yB-4fdgB:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fid | G PROTEIN ALPHASUBUNIT (Entamoebahistolytica) |
PF00503(G-alpha) | 5 | GLY A 30SER A 31GLU A 230ASP A 237ILE A 238 | None | 1.11A | 4u8yB-4fidA:undetectable | 4u8yB-4fidA:15.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fn6 | THIAMINASE-2 (Staphylococcusaureus) |
PF03070(TENA_THI-4) | 5 | GLU A 179ASN A 176ASP A 173ILE A 174PHE A 51 | None | 1.07A | 4u8yB-4fn6A:undetectable | 4u8yB-4fn6A:11.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fus | RTX TOXINS ANDRELATED CA2+-BINDINGPROTEIN (Hahellachejuensis) |
PF02011(Glyco_hydro_48) | 5 | PHE A 428GLY A 430ASP A 302ALA A 408VAL A 353 | NoneNoneNoneNoneOHI A 352 ( 3.1A) | 1.10A | 4u8yB-4fusA:undetectable | 4u8yB-4fusA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fyu | THIOREDOXIN (Wuchereriabancrofti) |
PF13905(Thioredoxin_8) | 5 | GLY A 20SER A 21ASN A 7ILE A 8VAL A 89 | None | 1.12A | 4u8yB-4fyuA:undetectable | 4u8yB-4fyuA:9.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g9k | ROTENONE-INSENSITIVENADH-UBIQUINONEOXIDOREDUCTASE (Saccharomycescerevisiae) |
PF07992(Pyr_redox_2) | 5 | GLY A 60SER A 61ILE A 82ALA A 129VAL A 139 | GLY A 60 (-0.0A)SER A 61 (-0.0A)ILE A 82 (-0.7A)ALA A 129 (-0.0A)VAL A 139 ( 0.6A) | 0.90A | 4u8yB-4g9kA:undetectable | 4u8yB-4g9kA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hea | NADH-QUINONEOXIDOREDUCTASESUBUNIT 13 (Thermusthermophilus) |
PF00361(Proton_antipo_M) | 5 | GLY M 237ALA M 297PHE M 301VAL M 300PHE M 242 | None | 1.13A | 4u8yB-4heaM:undetectable | 4u8yB-4heaM:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hwt | THREONINE--TRNALIGASE, CYTOPLASMIC (Homo sapiens) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon) | 5 | PHE A 559GLU A 564ASN A 530ASP A 578ILE A 577 | NoneNoneNone1B2 A 802 (-3.7A)None | 1.14A | 4u8yB-4hwtA:undetectable | 4u8yB-4hwtA:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jdn | VIRULENCE PLASMIDPROTEIN PGP3-D (Chlamydiatrachomatis) |
PF05475(Chlam_vir) | 5 | SER A 194ASP A 168ILE A 169ALA A 171VAL A 235 | None | 1.08A | 4u8yB-4jdnA:undetectable | 4u8yB-4jdnA:10.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jdo | VIRULENCE PLASMIDPROTEIN PGP3-D (Chlamydiatrachomatis) |
PF05475(Chlam_vir) | 5 | SER A 194ASP A 168ILE A 169ALA A 171VAL A 235 | None | 1.08A | 4u8yB-4jdoA:undetectable | 4u8yB-4jdoA:12.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kq9 | RIBOSE ABCTRANSPORTER,SUBSTRATE BINDINGPROTEIN (Conexibacterwoesei) |
PF13407(Peripla_BP_4) | 5 | GLY A 150SER A 151ILE A 294ALA A 295VAL A 298 | NoneGOL A 501 ( 4.9A)NoneNoneNone | 1.05A | 4u8yB-4kq9A:undetectable | 4u8yB-4kq9A:14.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ll1 | THIOREDOXIN-INTERACTING PROTEIN (Homo sapiens) |
PF00339(Arrestin_N)PF02752(Arrestin_C) | 5 | GLY A 102ILE A 46ALA A 48PHE A 143VAL A 125 | None | 1.12A | 4u8yB-4ll1A:undetectable | 4u8yB-4ll1A:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nt4 | GILGAMESH, ISOFORM I (Drosophilamelanogaster) |
PF00069(Pkinase) | 5 | GLU A 74ILE A 71ALA A 70VAL A 69PHE A 43 | None | 1.01A | 4u8yB-4nt4A:undetectable | 4u8yB-4nt4A:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qko | PYOCIN-S2PYOCIN-S2 IMMUNITYPROTEIN (Pseudomonasaeruginosa) |
PF01320(Colicin_Pyocin)no annotation | 5 | GLY B 628ASP A 19ILE A 20VAL A 38PHE A 41 | None | 1.07A | 4u8yB-4qkoB:undetectable | 4u8yB-4qkoB:7.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tkd | HOLLIDAY JUNCTIONRESOLVASE HJC (Sulfolobussolfataricus) |
PF01870(Hjc) | 5 | ASP A 42ILE A 43ALA A 45PHE A 24VAL A 26 | None | 1.09A | 4u8yB-4tkdA:undetectable | 4u8yB-4tkdA:8.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u3t | PENICILLIN-BINDINGPROTEIN 2 (Neisseriagonorrhoeae) |
PF00905(Transpeptidase) | 5 | PHE A 315SER A 419ILE A 317ALA A 318PHE A 462 | None | 1.07A | 4u8yB-4u3tA:undetectable | 4u8yB-4u3tA:15.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u3t | PENICILLIN-BINDINGPROTEIN 2 (Neisseriagonorrhoeae) |
PF00905(Transpeptidase) | 5 | PHE A 315SER A 419ILE A 317ALA A 318VAL A 470 | None | 1.12A | 4u8yB-4u3tA:undetectable | 4u8yB-4u3tA:15.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wbd | BSHC (Bacillussubtilis) |
PF10079(BshC) | 5 | ASN A 12ILE A 354ALA A 349PHE A 347VAL A 374 | None | 1.03A | 4u8yB-4wbdA:3.5 | 4u8yB-4wbdA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wbd | BSHC (Bacillussubtilis) |
PF10079(BshC) | 5 | GLY A 352ASN A 12ALA A 349PHE A 347VAL A 374 | CIT A 602 (-3.5A)NoneNoneNoneNone | 1.08A | 4u8yB-4wbdA:3.5 | 4u8yB-4wbdA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wyu | PROTEIN SCRIBBLEHOMOLOG (Homo sapiens) |
PF00595(PDZ) | 5 | GLY A 30SER A 36ILE A 28ALA A 84VAL A 85 | None | 1.06A | 4u8yB-4wyuA:undetectable | 4u8yB-4wyuA:12.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xhg | SIMILAR TOUNIPROT|P29295SACCHAROMYCESCEREVISIAE YPL204WHRR25 ([Candida]glabrata) |
PF00069(Pkinase) | 5 | GLU A 40ILE A 37ALA A 36VAL A 35PHE A 9 | NoneNoneADP A 501 ( 3.7A)NoneNone | 1.04A | 4u8yB-4xhgA:undetectable | 4u8yB-4xhgA:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xhl | CASEIN KINASE IHOMOLOG HRR25 (Saccharomycescerevisiae) |
PF00069(Pkinase) | 5 | GLU A 40ILE A 37ALA A 36VAL A 35PHE A 9 | NoneNoneCKI A 401 (-3.3A)NoneNone | 0.95A | 4u8yB-4xhlA:undetectable | 4u8yB-4xhlA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xup | ENDO-1,4-BETA-XYLANASE C (Paenibacillusbarcinonensis) |
PF02018(CBM_4_9) | 5 | GLU A 195ALA A 176PHE A 174VAL A 327PHE A 238 | None | 0.85A | 4u8yB-4xupA:undetectable | 4u8yB-4xupA:15.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xut | ENDO-1,4-BETA-XYLANASE C (Paenibacillusbarcinonensis) |
PF02018(CBM_4_9) | 5 | GLU A 195ALA A 176PHE A 174VAL A 327PHE A 238 | None | 0.90A | 4u8yB-4xutA:undetectable | 4u8yB-4xutA:10.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z2q | LECTIN (Athelia rolfsii) |
PF07367(FB_lectin) | 5 | GLU A 61ASN A 116ILE A 78ALA A 65PHE A 67 | None | 1.14A | 4u8yB-4z2qA:undetectable | 4u8yB-4z2qA:9.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bq2 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00275(EPSP_synthase) | 5 | GLY A 401ILE A 398ALA A 377VAL A 380ARG A 418 | None | 1.15A | 4u8yB-5bq2A:undetectable | 4u8yB-5bq2A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c5g | SPHERULIN-4 (Aspergillusclavatus) |
PF12138(Spherulin4) | 5 | PHE A 221ILE A 278ALA A 275PHE A 237VAL A 271 | None | 1.08A | 4u8yB-5c5gA:undetectable | 4u8yB-5c5gA:13.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cdf | ATP SYNTHASE SUBUNITBETA (Paracoccusdenitrificans) |
PF00006(ATP-synt_ab)PF02874(ATP-synt_ab_N) | 5 | GLU E 95ASN E 91ALA E 212PHE E 239VAL E 177 | None | 1.05A | 4u8yB-5cdfE:undetectable | 4u8yB-5cdfE:19.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5eno | MULTIDRUG EFFLUXPUMP SUBUNITACRB,MULTIDRUGEFFLUX PUMP SUBUNITACRB (Escherichiacoli) |
PF00873(ACR_tran) | 6 | ASP A 276ILE A 277ALA A 279PHE A 610VAL A 612PHE A 615 | None | 0.76A | 4u8yB-5enoA:43.9 | 4u8yB-5enoA:73.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5eno | MULTIDRUG EFFLUXPUMP SUBUNITACRB,MULTIDRUGEFFLUX PUMP SUBUNITACRB (Escherichiacoli) |
PF00873(ACR_tran) | 5 | GLU A 273ASN A 274ASP A 276ALA A 279PHE A 610 | None | 0.96A | 4u8yB-5enoA:43.9 | 4u8yB-5enoA:73.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5eno | MULTIDRUG EFFLUXPUMP SUBUNITACRB,MULTIDRUGEFFLUX PUMP SUBUNITACRB (Escherichiacoli) |
PF00873(ACR_tran) | 6 | GLU A 273ASP A 276ILE A 277ALA A 279PHE A 610VAL A 612 | None | 0.85A | 4u8yB-5enoA:43.9 | 4u8yB-5enoA:73.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5eno | MULTIDRUG EFFLUXPUMP SUBUNITACRB,MULTIDRUGEFFLUX PUMP SUBUNITACRB (Escherichiacoli) |
PF00873(ACR_tran) | 6 | GLY A 179SER A 180GLU A 273ASN A 274ALA A 279PHE A 610 | None | 1.38A | 4u8yB-5enoA:43.9 | 4u8yB-5enoA:73.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5eno | MULTIDRUG EFFLUXPUMP SUBUNITACRB,MULTIDRUGEFFLUX PUMP SUBUNITACRB (Escherichiacoli) |
PF00873(ACR_tran) | 6 | ILE A 277ALA A 279PHE A 610VAL A 612PHE A 615ARG A 620 | None | 0.90A | 4u8yB-5enoA:43.9 | 4u8yB-5enoA:73.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gl9 | BETA-LACTAMASE (Burkholderiathailandensis) |
PF13354(Beta-lactamase2) | 5 | GLY A 224ASP A 276ILE A 279ALA A 282PHE A 47 | None | 1.13A | 4u8yB-5gl9A:undetectable | 4u8yB-5gl9A:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ikj | CRYPTIC LOCIREGULATOR 2 (Schizosaccharomycespombe) |
PF10383(Clr2)PF16761(Clr2_transil) | 5 | PHE A 372GLY A 374ILE A 319ALA A 510VAL A 511 | None | 0.82A | 4u8yB-5ikjA:undetectable | 4u8yB-5ikjA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ju6 | BETA-GLUCOSIDASE (Rasamsoniaemersonii) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 5 | GLY A 284SER A 283ILE A 322ALA A 316VAL A 317 | NAG A 918 (-3.1A)MAN A 922 ( 4.6A)NoneNAG A 917 ( 3.9A)None | 1.12A | 4u8yB-5ju6A:undetectable | 4u8yB-5ju6A:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jvb | PHOSPHONATE ABCTRANSPORTER,PERIPLASMICPHOSPHONATE-BINDINGPROTEIN (Trichodesmiumerythraeum) |
no annotation | 5 | GLY A 170GLU A 109ILE A 122ALA A 124VAL A 155 | None | 0.98A | 4u8yB-5jvbA:undetectable | 4u8yB-5jvbA:15.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ksh | PENICILLIN-BINDINGPROTEIN 2 (Neisseriagonorrhoeae) |
PF00905(Transpeptidase)PF03717(PBP_dimer) | 6 | PHE A 315SER A 419ILE A 317ALA A 318PHE A 462VAL A 470 | None | 1.28A | 4u8yB-5kshA:undetectable | 4u8yB-5kshA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n6u | BETA-MANNOSIDASE (Dictyoglomusthermophilum) |
PF00703(Glyco_hydro_2)PF02837(Glyco_hydro_2_N) | 6 | PHE A 383GLY A 422SER A 467ASN A 426ILE A 446VAL A 450 | None | 1.41A | 4u8yB-5n6uA:undetectable | 4u8yB-5n6uA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o7e | COLH PROTEIN (Hathewayahistolytica) |
no annotation | 5 | ASN A 573ASP A 572ILE A 575PHE A 544VAL A 527 | None | 1.10A | 4u8yB-5o7eA:2.9 | 4u8yB-5o7eA:6.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xqo | PCRGLX PROTEIN (Penicilliumchrysogenum) |
no annotation | 5 | GLU A 587ASN A 902ASP A 903ILE A 904PHE A 544 | ADA A1004 ( 3.7A)RAM A1003 ( 4.1A)NoneNoneNone | 1.09A | 4u8yB-5xqoA:undetectable | 4u8yB-5xqoA:5.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cn1 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Pseudomonasputida) |
no annotation | 5 | GLY A 401ILE A 398ALA A 377VAL A 380ARG A 418 | None | 1.09A | 4u8yB-6cn1A:undetectable | 4u8yB-6cn1A:8.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d0s | TBC1 DOMAIN FAMILYMEMBER 22B (Homo sapiens) |
no annotation | 5 | GLY A 483GLU A 480ALA A 489PHE A 440VAL A 444 | None | 1.08A | 4u8yB-6d0sA:undetectable | 4u8yB-6d0sA:5.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ey4 | GLDM (Flavobacteriumjohnsoniae) |
no annotation | 6 | GLY A 370ASN A 354ILE A 356ALA A 358VAL A 386PHE A 348 | None | 1.41A | 4u8yB-6ey4A:4.8 | 4u8yB-6ey4A:5.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fkh | ATP SYNTHASE SUBUNITBETA, CHLOROPLASTIC (Spinaciaoleracea) |
no annotation | 5 | GLU D 116ASN D 112ALA D 233PHE D 260VAL D 198 | None | 1.14A | 4u8yB-6fkhD:undetectable | 4u8yB-6fkhD:6.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gjt | - (-) |
no annotation | 5 | SER A 194ASP A 168ILE A 169ALA A 171VAL A 235 | None | 1.03A | 4u8yB-6gjtA:undetectable | 4u8yB-6gjtA:undetectable |