SIMILAR PATTERNS OF AMINO ACIDS FOR 4U8V_B_MIYB1103

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cby DELTA-ENDOTOXIN CYTB

(Bacillus
thuringiensis)
PF01338
(Bac_thur_toxin)
5 SER A  38
ASN A 238
ASP A 235
ILE A 236
PHE A  47
None
0.96A 4u8vB-1cbyA:
0.0
4u8vB-1cbyA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dbj IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
5 GLY H  33
ASN H  52
ILE H  51
ALA H  78
PHE H  69
AE2  H 229 (-3.5A)
None
None
None
None
1.10A 4u8vB-1dbjH:
0.4
4u8vB-1dbjH:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dj2 ADENYLOSUCCINATE
SYNTHETASE


(Arabidopsis
thaliana)
PF00709
(Adenylsucc_synt)
5 SER A  22
ASP A  46
ILE A  47
ALA A  49
VAL A  86
None
1.06A 4u8vB-1dj2A:
0.0
4u8vB-1dj2A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dj3 ADENYLOSUCCINATE
SYNTHETASE


(Triticum
aestivum)
PF00709
(Adenylsucc_synt)
5 SER A  21
ASP A  45
ILE A  46
ALA A  48
VAL A  85
None
1.04A 4u8vB-1dj3A:
undetectable
4u8vB-1dj3A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1epx FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE


(Leishmania
mexicana)
PF00274
(Glycolytic)
5 GLY A 246
ASP A 209
ILE A 208
ALA A 253
VAL A 258
None
1.13A 4u8vB-1epxA:
0.0
4u8vB-1epxA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1flg PROTEIN
(QUINOPROTEIN
ETHANOL
DEHYDROGENASE)


(Pseudomonas
aeruginosa)
PF01011
(PQQ)
PF13360
(PQQ_2)
5 GLN A  20
PHE A 253
ASN A  10
ASP A   7
ILE A   8
None
1.14A 4u8vB-1flgA:
0.0
4u8vB-1flgA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gji C-REL PROTO-ONCOGENE
PROTEIN


(Gallus gallus)
PF00554
(RHD_DNA_bind)
PF16179
(RHD_dimer)
5 GLY A 228
SER A 229
ASP A 201
ILE A 203
VAL A 190
None
1.15A 4u8vB-1gjiA:
undetectable
4u8vB-1gjiA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gri GROWTH FACTOR BOUND
PROTEIN 2


(Homo sapiens)
PF00017
(SH2)
PF00018
(SH3_1)
5 PHE A 167
GLY A 176
ILE A 183
ALA A 163
VAL A 210
None
1.08A 4u8vB-1griA:
undetectable
4u8vB-1griA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hqz ACTIN-BINDING
PROTEIN


(Saccharomyces
cerevisiae)
PF00241
(Cofilin_ADF)
5 PHE 1  99
ASP 1   7
ILE 1   6
ALA 1 105
VAL 1 106
None
1.16A 4u8vB-1hqz1:
undetectable
4u8vB-1hqz1:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nx8 CARBAPENEM SYNTHASE

(Pectobacterium
carotovorum)
PF02668
(TauD)
5 ASP A  20
ILE A  19
ALA A  17
VAL A  42
PHE A  24
None
1.04A 4u8vB-1nx8A:
undetectable
4u8vB-1nx8A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pww LETHAL FACTOR

(Bacillus
anthracis)
PF07737
(ATLF)
PF09156
(Anthrax-tox_M)
5 ASN A 767
ASP A 768
ALA A 696
VAL A 708
PHE A 714
None
1.16A 4u8vB-1pwwA:
undetectable
4u8vB-1pwwA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pz3 ALPHA-L-ARABINOFURAN
OSIDASE


(Geobacillus
stearothermophilus)
PF06964
(Alpha-L-AF_C)
5 GLN A 351
PHE A  75
GLY A  72
ILE A  28
VAL A  35
GOL  A 503 (-3.9A)
None
None
None
None
1.08A 4u8vB-1pz3A:
undetectable
4u8vB-1pz3A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v7v CHITOBIOSE
PHOSPHORYLASE


(Vibrio
proteolyticus)
PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36)
5 PHE A 717
GLY A 713
SER A 712
ASP A 350
ALA A 355
None
1.13A 4u8vB-1v7vA:
2.7
4u8vB-1v7vA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wf7 ENIGMA HOMOLOGUE
PROTEIN


(Mus musculus)
PF00595
(PDZ)
5 SER A   8
ASN A  81
ASP A  57
ILE A  56
ALA A  61
None
0.99A 4u8vB-1wf7A:
undetectable
4u8vB-1wf7A:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zq1 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT E


(Pyrococcus
abyssi)
PF02637
(GatB_Yqey)
PF02934
(GatB_N)
PF02938
(GAD)
5 GLY C 347
ASP C 339
ALA C 392
VAL C 396
PHE C 337
None
1.17A 4u8vB-1zq1C:
2.2
4u8vB-1zq1C:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zz3 HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE


(Alcaligenaceae
bacterium FB188)
PF00850
(Hist_deacetyl)
5 ASP A  69
ILE A  72
ALA A  75
VAL A 160
ARG A 112
None
1.06A 4u8vB-1zz3A:
undetectable
4u8vB-1zz3A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2acg PROFILIN II

(Acanthamoeba
castellanii)
PF00235
(Profilin)
5 PHE A  60
SER A  57
ASP A  51
ALA A  44
PHE A  49
None
1.17A 4u8vB-2acgA:
undetectable
4u8vB-2acgA:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bl0 MYOSIN REGULATORY
LIGHT CHAIN


(Physarum
polycephalum)
PF00036
(EF-hand_1)
PF13499
(EF-hand_7)
5 GLN B  49
GLY B  48
ASN B  44
ILE B  46
VAL B  63
None
1.13A 4u8vB-2bl0B:
undetectable
4u8vB-2bl0B:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c6x CITRATE SYNTHASE 1

(Bacillus
subtilis)
PF00285
(Citrate_synt)
5 PHE A  51
GLY A  52
ILE A  49
ALA A 338
VAL A 334
None
1.16A 4u8vB-2c6xA:
undetectable
4u8vB-2c6xA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cy8 D-PHENYLGLYCINE
AMINOTRANSFERASE


(Pseudomonas
stutzeri)
PF00202
(Aminotran_3)
5 GLY A 360
ASN A 331
ASP A 332
ALA A 337
VAL A 421
None
1.15A 4u8vB-2cy8A:
undetectable
4u8vB-2cy8A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dig LAMIN-B RECEPTOR

(Homo sapiens)
PF09465
(LBR_tudor)
5 ASP A  15
ILE A  34
VAL A  19
PHE A  13
ARG A  11
None
1.18A 4u8vB-2digA:
undetectable
4u8vB-2digA:
5.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eo0 HYPOTHETICAL PROTEIN
ST1444


(Sulfurisphaera
tokodaii)
PF01870
(Hjc)
5 ASP A  45
ILE A  46
ALA A  48
PHE A  27
VAL A  29
None
1.07A 4u8vB-2eo0A:
undetectable
4u8vB-2eo0A:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fji EXOCYST COMPLEX
COMPONENT SEC6


(Saccharomyces
cerevisiae)
PF06046
(Sec6)
6 SER 1 597
ASN 1 651
ASP 1 654
ILE 1 653
VAL 1 699
PHE 1 696
None
1.38A 4u8vB-2fji1:
2.2
4u8vB-2fji1:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jir PERIPLASMIC NITRATE
REDUCTASE


(Desulfovibrio
desulfuricans)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4)
5 ASP A 215
ILE A 201
ALA A 203
PHE A 220
VAL A 218
None
None
None
MGD  A 812 (-4.7A)
None
1.14A 4u8vB-2jirA:
undetectable
4u8vB-2jirA:
22.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oej 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE


(Geobacillus
kaustophilus)
PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N)
5 GLY A 286
SER A 282
ASP A 322
ALA A 330
PHE A 327
None
1.13A 4u8vB-2oejA:
3.3
4u8vB-2oejA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pq6 UDP-GLUCURONOSYL/UDP
-GLUCOSYLTRANSFERASE


(Medicago
truncatula)
PF00201
(UDPGT)
5 PHE A 302
GLY A 303
SER A 304
ILE A 330
PHE A 375
None
1.15A 4u8vB-2pq6A:
undetectable
4u8vB-2pq6A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyw UNCHARACTERIZED
PROTEIN


(Arabidopsis
thaliana)
PF01636
(APH)
5 SER A 391
ILE A 416
ALA A 415
PHE A 406
VAL A 412
None
1.06A 4u8vB-2pywA:
undetectable
4u8vB-2pywA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qy6 UPF0209 PROTEIN YFCK

(Escherichia
coli)
PF05430
(Methyltransf_30)
5 GLY A  65
ASP A 198
ALA A 194
PHE A  80
VAL A  82
None
1.00A 4u8vB-2qy6A:
undetectable
4u8vB-2qy6A:
12.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yut PUTATIVE SHORT-CHAIN
OXIDOREDUCTASE


(Thermus
thermophilus)
PF00106
(adh_short)
5 GLY A  14
ILE A   5
ALA A  73
PHE A 119
VAL A  71
None
None
NAP  A 500 (-4.1A)
NAP  A 500 ( 4.4A)
None
1.14A 4u8vB-2yutA:
undetectable
4u8vB-2yutA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afl OLIGO ALGINATE LYASE

(Agrobacterium
fabrum)
PF07940
(Hepar_II_III)
PF16332
(DUF4962)
5 GLY A 362
ILE A 501
ALA A 353
PHE A 393
PHE A 498
None
1.11A 4u8vB-3aflA:
2.8
4u8vB-3aflA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE


(Mycobacterium
gastri)
PF00215
(OMPdecase)
5 GLY A1127
ASP A1089
ILE A1092
ALA A1095
ARG A1119
None
1.06A 4u8vB-3ajxA:
undetectable
4u8vB-3ajxA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dui BETA-GALACTOSIDE-BIN
DING LECTIN


(Gallus gallus)
PF00337
(Gal-bind_lectin)
5 GLY A  22
ASP A 125
ILE A  24
ALA A  84
PHE A  80
None
1.06A 4u8vB-3duiA:
undetectable
4u8vB-3duiA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04


(Sarcoptes
scabiei)
PF00089
(Trypsin)
5 SER A 107
ASP A  71
ILE A  56
ALA A  17
VAL A  18
None
0.98A 4u8vB-3h7oA:
undetectable
4u8vB-3h7oA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hyi PROTEIN DUF199/WHIA

(Thermotoga
maritima)
PF02650
(HTH_WhiA)
PF10298
(WhiA_N)
PF14527
(LAGLIDADG_WhiA)
5 GLY A 160
ASN A 158
ASP A 177
ILE A 172
PHE A 181
None
1.09A 4u8vB-3hyiA:
undetectable
4u8vB-3hyiA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lga SAM-DEPENDENT
METHYLTRANSFERASE


(Pyrococcus
abyssi)
PF08704
(GCD14)
PF14801
(GCD14_N)
5 ASN A 221
ILE A 247
ALA A 192
PHE A 190
VAL A 191
None
1.14A 4u8vB-3lgaA:
undetectable
4u8vB-3lgaA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o07 PYRIDOXINE
BIOSYNTHESIS PROTEIN
SNZ1


(Saccharomyces
cerevisiae)
PF01680
(SOR_SNZ)
5 ASN A  71
ASP A  68
ILE A  69
ALA A  30
VAL A  24
None
1.16A 4u8vB-3o07A:
undetectable
4u8vB-3o07A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oet ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE


(Salmonella
enterica)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
PF11890
(DUF3410)
5 PHE A  84
GLY A  83
ASN A  60
ALA A 273
VAL A 270
None
1.15A 4u8vB-3oetA:
undetectable
4u8vB-3oetA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oq3 INTERFERON ALPHA-5

(Mus musculus)
PF00143
(Interferon)
5 PHE A  38
GLY A  37
ALA A 119
VAL A 120
PHE A 124
None
1.15A 4u8vB-3oq3A:
undetectable
4u8vB-3oq3A:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pow CALRETICULIN

(Homo sapiens)
PF00262
(Calreticulin)
5 GLN A 101
GLY A 106
ASP A 165
PHE A 327
VAL A  97
None
0.94A 4u8vB-3powA:
undetectable
4u8vB-3powA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rg0 CALRETICULIN

(Mus musculus)
PF00262
(Calreticulin)
5 GLN A 101
GLY A 106
ASP A 165
PHE A 327
VAL A  97
None
1.02A 4u8vB-3rg0A:
undetectable
4u8vB-3rg0A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqh QUINONE
OXIDOREDUCTASE


(Coxiella
burnetii)
PF08240
(ADH_N)
PF13602
(ADH_zinc_N_2)
5 PHE A  55
GLY A  54
SER A  53
ASP A  46
ILE A  45
None
None
None
None
SO4  A 319 (-3.9A)
1.17A 4u8vB-3tqhA:
undetectable
4u8vB-3tqhA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE


(Corynebacterium
glutamicum)
PF01546
(Peptidase_M20)
PF07687
(M20_dimer)
5 GLN A 365
ASP A 358
ILE A 362
ALA A 308
VAL A 309
None
1.10A 4u8vB-3tx8A:
6.5
4u8vB-3tx8A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vwo PEPTIDOGLYCAN
HYDROLASE FLGJ


(Sphingomonas
sp. A1)
PF01832
(Glucosaminidase)
6 GLY A 189
SER A 191
ALA A 182
PHE A 247
VAL A 179
ARG A 303
None
1.36A 4u8vB-3vwoA:
undetectable
4u8vB-3vwoA:
10.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9h ACRIFLAVINE
RESISTANCE PROTEIN B


(Escherichia
coli)
PF00873
(ACR_tran)
6 ASN A 274
ASP A 276
ALA A 279
PHE A 610
VAL A 612
PHE A 615
None
0.89A 4u8vB-3w9hA:
40.6
4u8vB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9h ACRIFLAVINE
RESISTANCE PROTEIN B


(Escherichia
coli)
PF00873
(ACR_tran)
7 GLN A 151
ASP A 276
ILE A 277
ALA A 279
PHE A 610
VAL A 612
PHE A 615
None
0.78A 4u8vB-3w9hA:
40.6
4u8vB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9h ACRIFLAVINE
RESISTANCE PROTEIN B


(Escherichia
coli)
PF00873
(ACR_tran)
5 GLN A 151
SER A 180
ALA A 279
PHE A 610
VAL A 612
None
1.02A 4u8vB-3w9hA:
40.6
4u8vB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9h ACRIFLAVINE
RESISTANCE PROTEIN B


(Escherichia
coli)
PF00873
(ACR_tran)
5 GLY A 179
ALA A 279
PHE A 610
VAL A 612
PHE A 615
None
0.93A 4u8vB-3w9hA:
40.6
4u8vB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9h ACRIFLAVINE
RESISTANCE PROTEIN B


(Escherichia
coli)
PF00873
(ACR_tran)
5 GLY A 179
SER A 180
ALA A 279
PHE A 610
VAL A 612
None
0.97A 4u8vB-3w9hA:
40.6
4u8vB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9h ACRIFLAVINE
RESISTANCE PROTEIN B


(Escherichia
coli)
PF00873
(ACR_tran)
5 SER A 180
ASN A 274
ALA A 279
PHE A 610
VAL A 612
None
1.04A 4u8vB-3w9hA:
40.6
4u8vB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9i MULTIDRUG RESISTANCE
PROTEIN MEXB


(Pseudomonas
aeruginosa)
PF00873
(ACR_tran)
5 GLY A 179
SER A 180
ALA A 279
PHE A 610
ARG A 620
None
1.09A 4u8vB-3w9iA:
37.8
4u8vB-3w9iA:
69.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9i MULTIDRUG RESISTANCE
PROTEIN MEXB


(Pseudomonas
aeruginosa)
PF00873
(ACR_tran)
5 GLY A 179
SER A 180
ALA A 279
PHE A 610
PHE A 615
None
0.82A 4u8vB-3w9iA:
37.8
4u8vB-3w9iA:
69.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9i MULTIDRUG RESISTANCE
PROTEIN MEXB


(Pseudomonas
aeruginosa)
PF00873
(ACR_tran)
5 ILE A 277
ALA A 279
PHE A 610
VAL A 612
ARG A 620
None
0.95A 4u8vB-3w9iA:
37.8
4u8vB-3w9iA:
69.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3w9i MULTIDRUG RESISTANCE
PROTEIN MEXB


(Pseudomonas
aeruginosa)
PF00873
(ACR_tran)
5 ILE A 277
ALA A 279
PHE A 610
VAL A 612
PHE A 615
None
0.75A 4u8vB-3w9iA:
37.8
4u8vB-3w9iA:
69.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b3i FATTY ACID
BETA-OXIDATION
COMPLEX ALPHA-CHAIN
FADB


(Mycobacterium
tuberculosis)
PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N)
5 SER A 168
ASN A 164
ILE A 162
ALA A 268
VAL A 269
None
1.08A 4u8vB-4b3iA:
undetectable
4u8vB-4b3iA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN


(Carboxydothermus
hydrogenoformans)
PF14574
(DUF4445)
5 GLY I 466
SER I 465
ASP I 469
ILE I 468
PHE I 486
None
0.89A 4u8vB-4c1nI:
undetectable
4u8vB-4c1nI:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4csq UNCHARACTERIZED
PROTEIN


(Pseudomonas
aeruginosa)
no annotation 5 SER A  88
ASP A  23
ILE A  22
PHE A  30
VAL A  59
None
1.15A 4u8vB-4csqA:
undetectable
4u8vB-4csqA:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4el8 GLYCOSIDE HYDROLASE
FAMILY 48


(Caldicellulosiruptor
bescii)
PF02011
(Glyco_hydro_48)
5 PHE A 393
GLY A 395
ASP A 271
ALA A 375
VAL A 320
None
1.13A 4u8vB-4el8A:
undetectable
4u8vB-4el8A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0a PROTEIN WNT-8

(Xenopus laevis)
PF00110
(wnt)
5 ASN B 207
ASP B 204
ILE B 205
ALA B 172
VAL B 173
None
0.96A 4u8vB-4f0aB:
undetectable
4u8vB-4f0aB:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f99 CELL DIVISION CYCLE
7-RELATED PROTEIN
KINASE


(Homo sapiens)
PF00069
(Pkinase)
5 PHE A 404
GLY A 401
ASP A 551
ALA A 563
PHE A 569
None
1.02A 4u8vB-4f99A:
undetectable
4u8vB-4f99A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fus RTX TOXINS AND
RELATED CA2+-BINDING
PROTEIN


(Hahella
chejuensis)
PF02011
(Glyco_hydro_48)
5 PHE A 428
GLY A 430
ASP A 302
ALA A 408
VAL A 353
None
None
None
None
OHI  A 352 ( 3.1A)
1.06A 4u8vB-4fusA:
undetectable
4u8vB-4fusA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fyu THIOREDOXIN

(Wuchereria
bancrofti)
PF13905
(Thioredoxin_8)
5 GLY A  20
SER A  21
ASN A   7
ILE A   8
VAL A  89
None
1.15A 4u8vB-4fyuA:
undetectable
4u8vB-4fyuA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g9k ROTENONE-INSENSITIVE
NADH-UBIQUINONE
OXIDOREDUCTASE


(Saccharomyces
cerevisiae)
PF07992
(Pyr_redox_2)
5 GLY A  60
SER A  61
ILE A  82
ALA A 129
VAL A 139
GLY  A  60 (-0.0A)
SER  A  61 (-0.0A)
ILE  A  82 (-0.7A)
ALA  A 129 (-0.0A)
VAL  A 139 ( 0.6A)
0.87A 4u8vB-4g9kA:
undetectable
4u8vB-4g9kA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ga6 PUTATIVE THYMIDINE
PHOSPHORYLASE


(Thermococcus
kodakarensis)
PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C)
5 GLY A  60
ILE A   5
ALA A   3
VAL A  77
PHE A  71
None
1.14A 4u8vB-4ga6A:
2.9
4u8vB-4ga6A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gei THIOREDOXIN-INTERACT
ING PROTEIN


(Homo sapiens)
PF00339
(Arrestin_N)
5 GLY A 102
ILE A  46
ALA A  48
PHE A 143
VAL A 125
None
1.15A 4u8vB-4geiA:
undetectable
4u8vB-4geiA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 13


(Thermus
thermophilus)
PF00361
(Proton_antipo_M)
5 GLY M 237
ALA M 297
PHE M 301
VAL M 300
PHE M 242
None
1.15A 4u8vB-4heaM:
1.6
4u8vB-4heaM:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jdn VIRULENCE PLASMID
PROTEIN PGP3-D


(Chlamydia
trachomatis)
PF05475
(Chlam_vir)
5 SER A 194
ASP A 168
ILE A 169
ALA A 171
VAL A 235
None
1.08A 4u8vB-4jdnA:
undetectable
4u8vB-4jdnA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jdo VIRULENCE PLASMID
PROTEIN PGP3-D


(Chlamydia
trachomatis)
PF05475
(Chlam_vir)
5 SER A 194
ASP A 168
ILE A 169
ALA A 171
VAL A 235
None
1.07A 4u8vB-4jdoA:
undetectable
4u8vB-4jdoA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kq9 RIBOSE ABC
TRANSPORTER,
SUBSTRATE BINDING
PROTEIN


(Conexibacter
woesei)
PF13407
(Peripla_BP_4)
5 GLY A 150
SER A 151
ILE A 294
ALA A 295
VAL A 298
None
GOL  A 501 ( 4.9A)
None
None
None
1.04A 4u8vB-4kq9A:
undetectable
4u8vB-4kq9A:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ll1 THIOREDOXIN-INTERACT
ING PROTEIN


(Homo sapiens)
PF00339
(Arrestin_N)
PF02752
(Arrestin_C)
5 GLY A 102
ILE A  46
ALA A  48
PHE A 143
VAL A 125
None
1.12A 4u8vB-4ll1A:
undetectable
4u8vB-4ll1A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfm 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE


(Shewanella
benthica)
PF00701
(DHDPS)
5 ASN A 156
ASP A 127
ILE A 128
ALA A  98
VAL A  97
None
1.16A 4u8vB-4pfmA:
undetectable
4u8vB-4pfmA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qey UNCHARACTERIZED
PROTEIN


(Bacteroides
ovatus)
PF14466
(PLCC)
5 GLN A  42
ASN A  45
ASP A  48
PHE A 147
VAL A 105
EDO  A 202 (-3.1A)
None
None
None
None
1.15A 4u8vB-4qeyA:
undetectable
4u8vB-4qeyA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qko PYOCIN-S2
PYOCIN-S2 IMMUNITY
PROTEIN


(Pseudomonas
aeruginosa)
PF01320
(Colicin_Pyocin)
no annotation
5 GLY B 628
ASP A  19
ILE A  20
VAL A  38
PHE A  41
None
1.07A 4u8vB-4qkoB:
undetectable
4u8vB-4qkoB:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tkd HOLLIDAY JUNCTION
RESOLVASE HJC


(Sulfolobus
solfataricus)
PF01870
(Hjc)
5 ASP A  42
ILE A  43
ALA A  45
PHE A  24
VAL A  26
None
1.07A 4u8vB-4tkdA:
undetectable
4u8vB-4tkdA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3a ENDOGLUCANASE H

(Ruminiclostridium
thermocellum)
PF00150
(Cellulase)
5 GLY A 350
ASP A 370
ILE A 361
VAL A 346
ARG A 326
None
1.18A 4u8vB-4u3aA:
undetectable
4u8vB-4u3aA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3t PENICILLIN-BINDING
PROTEIN 2


(Neisseria
gonorrhoeae)
PF00905
(Transpeptidase)
5 PHE A 315
SER A 419
ILE A 317
ALA A 318
PHE A 462
None
1.07A 4u8vB-4u3tA:
undetectable
4u8vB-4u3tA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3t PENICILLIN-BINDING
PROTEIN 2


(Neisseria
gonorrhoeae)
PF00905
(Transpeptidase)
5 PHE A 315
SER A 419
ILE A 317
ALA A 318
VAL A 470
None
1.07A 4u8vB-4u3tA:
undetectable
4u8vB-4u3tA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbd BSHC

(Bacillus
subtilis)
PF10079
(BshC)
5 ASN A  12
ILE A 354
ALA A 349
PHE A 347
VAL A 374
None
0.99A 4u8vB-4wbdA:
4.0
4u8vB-4wbdA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbd BSHC

(Bacillus
subtilis)
PF10079
(BshC)
5 GLY A 352
ASN A  12
ALA A 349
PHE A 347
VAL A 374
CIT  A 602 (-3.5A)
None
None
None
None
1.06A 4u8vB-4wbdA:
4.0
4u8vB-4wbdA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wyu PROTEIN SCRIBBLE
HOMOLOG


(Homo sapiens)
PF00595
(PDZ)
5 GLY A  30
SER A  36
ILE A  28
ALA A  84
VAL A  85
None
1.09A 4u8vB-4wyuA:
undetectable
4u8vB-4wyuA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y9w ASPARTIC ACID
ENDOPEPTIDASE SAPP2


(Candida
parapsilosis)
PF00026
(Asp)
5 GLY A  21
SER A  22
ASP A  59
PHE A  38
VAL A  40
None
1.16A 4u8vB-4y9wA:
undetectable
4u8vB-4y9wA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bq2 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE


(Pseudomonas
aeruginosa)
PF00275
(EPSP_synthase)
5 GLY A 401
ILE A 398
ALA A 377
VAL A 380
ARG A 418
None
1.15A 4u8vB-5bq2A:
undetectable
4u8vB-5bq2A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c5g SPHERULIN-4

(Aspergillus
clavatus)
PF12138
(Spherulin4)
5 PHE A 221
ILE A 278
ALA A 275
PHE A 237
VAL A 271
None
1.08A 4u8vB-5c5gA:
undetectable
4u8vB-5c5gA:
13.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eno MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB


(Escherichia
coli)
PF00873
(ACR_tran)
7 ASP A 276
ILE A 277
ALA A 279
PHE A 610
VAL A 612
PHE A 615
ARG A 620
None
0.91A 4u8vB-5enoA:
35.1
4u8vB-5enoA:
73.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eno MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB


(Escherichia
coli)
PF00873
(ACR_tran)
7 GLN A 151
ASP A 276
ILE A 277
PHE A 610
VAL A 612
PHE A 615
ARG A 620
None
1.07A 4u8vB-5enoA:
35.1
4u8vB-5enoA:
73.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5eno MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB


(Escherichia
coli)
PF00873
(ACR_tran)
5 PHE A 178
GLY A 179
SER A 180
ILE A 278
PHE A 610
None
1.18A 4u8vB-5enoA:
35.1
4u8vB-5enoA:
73.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f5o NUCLEOPROTEIN

(Marburg
marburgvirus)
PF05505
(Ebola_NP)
5 GLY A  45
ASN A  43
ASP A  40
ALA A 115
PHE A  99
None
1.11A 4u8vB-5f5oA:
undetectable
4u8vB-5f5oA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fse UREASE SUBUNIT ALPHA

(Sporosarcina
pasteurii)
PF00449
(Urease_alpha)
PF01979
(Amidohydro_1)
5 GLY C 200
ASP C 233
ILE C 232
ALA C 227
ARG C 269
KCX  C 220 ( 3.2A)
None
None
None
None
1.10A 4u8vB-5fseC:
undetectable
4u8vB-5fseC:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gl9 BETA-LACTAMASE

(Burkholderia
thailandensis)
PF13354
(Beta-lactamase2)
5 GLY A 224
ASP A 276
ILE A 279
ALA A 282
PHE A  47
None
1.13A 4u8vB-5gl9A:
2.5
4u8vB-5gl9A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gl9 BETA-LACTAMASE

(Burkholderia
thailandensis)
PF13354
(Beta-lactamase2)
5 GLY A 224
ASP A 276
ILE A 279
PHE A  47
VAL A 263
None
1.14A 4u8vB-5gl9A:
2.5
4u8vB-5gl9A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikj CRYPTIC LOCI
REGULATOR 2


(Schizosaccharomyces
pombe)
PF10383
(Clr2)
PF16761
(Clr2_transil)
5 PHE A 372
GLY A 374
ILE A 319
ALA A 510
VAL A 511
None
0.78A 4u8vB-5ikjA:
undetectable
4u8vB-5ikjA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksh PENICILLIN-BINDING
PROTEIN 2


(Neisseria
gonorrhoeae)
PF00905
(Transpeptidase)
PF03717
(PBP_dimer)
5 PHE A 315
SER A 419
ILE A 317
ALA A 318
PHE A 462
None
1.13A 4u8vB-5kshA:
undetectable
4u8vB-5kshA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksh PENICILLIN-BINDING
PROTEIN 2


(Neisseria
gonorrhoeae)
PF00905
(Transpeptidase)
PF03717
(PBP_dimer)
5 PHE A 315
SER A 419
ILE A 317
ALA A 318
VAL A 470
None
1.15A 4u8vB-5kshA:
undetectable
4u8vB-5kshA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6u BETA-MANNOSIDASE

(Dictyoglomus
thermophilum)
PF00703
(Glyco_hydro_2)
PF02837
(Glyco_hydro_2_N)
6 PHE A 383
GLY A 422
SER A 467
ASN A 426
ILE A 446
VAL A 450
None
1.42A 4u8vB-5n6uA:
undetectable
4u8vB-5n6uA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ncc FATTY ACID
PHOTODECARBOXYLASE


(Chlorella
variabilis)
PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C)
5 GLY A 622
ASN A 170
ASP A 275
ALA A  94
VAL A  97
FAD  A 701 (-3.5A)
FAD  A 701 (-3.3A)
None
FAD  A 701 (-3.6A)
None
1.17A 4u8vB-5nccA:
undetectable
4u8vB-5nccA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o7e COLH PROTEIN

(Hathewaya
histolytica)
no annotation 5 ASN A 573
ASP A 572
ILE A 575
PHE A 544
VAL A 527
None
1.12A 4u8vB-5o7eA:
undetectable
4u8vB-5o7eA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubc PROTEIN TOC75-3,
CHLOROPLASTIC


(Arabidopsis
thaliana)
no annotation 5 GLN A 400
ASP A 365
ILE A 366
VAL A 441
PHE A 404
None
1.13A 4u8vB-5ubcA:
undetectable
4u8vB-5ubcA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vld HISTIDINOL
DEHYDROGENASE,
CHLOROPLASTIC


(Medicago
truncatula)
PF00815
(Histidinol_dh)
5 ASN A 320
ASP A 318
ILE A 322
ALA A 293
VAL A 292
None
1.16A 4u8vB-5vldA:
undetectable
4u8vB-5vldA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cn1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE


(Pseudomonas
putida)
no annotation 5 GLY A 401
ILE A 398
ALA A 377
VAL A 380
ARG A 418
None
1.08A 4u8vB-6cn1A:
undetectable
4u8vB-6cn1A:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ey4 GLDM

(Flavobacterium
johnsoniae)
no annotation 6 GLY A 370
ASN A 354
ILE A 356
ALA A 358
VAL A 386
PHE A 348
None
1.47A 4u8vB-6ey4A:
3.7
4u8vB-6ey4A:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gjt -

(-)
no annotation 5 SER A 194
ASP A 168
ILE A 169
ALA A 171
VAL A 235
None
1.03A 4u8vB-6gjtA:
undetectable
4u8vB-6gjtA:
undetectable