SIMILAR PATTERNS OF AMINO ACIDS FOR 4U5J_A_RXTA601

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1k9a CARBOXYL-TERMINAL
SRC KINASE


(Rattus
norvegicus)
PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr)
9 GLY A 204
VAL A 209
ALA A 220
TYR A 268
MET A 269
GLY A 272
ASN A 319
LEU A 321
ASP A 332
None
0.41A 4u5jA-1k9aA:
34.1
4u5jA-1k9aA:
30.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1k9a CARBOXYL-TERMINAL
SRC KINASE


(Rattus
norvegicus)
PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr)
9 GLY A 207
VAL A 209
ALA A 220
TYR A 268
MET A 269
GLY A 272
ASN A 319
LEU A 321
ASP A 332
None
1.02A 4u5jA-1k9aA:
34.1
4u5jA-1k9aA:
30.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK


(Rattus
norvegicus)
PF07714
(Pkinase_Tyr)
10 GLY A 583
VAL A 588
ALA A 606
TYR A 656
MET A 657
GLY A 660
ASN A 729
LEU A 731
ALA A 741
ASP A 742
None
0.92A 4u5jA-1lufA:
32.9
4u5jA-1lufA:
32.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1opk PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1


(Mus musculus)
PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr)
8 LEU A 267
VAL A 275
ALA A 288
MET A 337
GLY A 340
ASN A 387
LEU A 389
ALA A 399
P16  A   2 ( 4.2A)
P16  A   2 (-4.5A)
P16  A   2 (-3.4A)
None
P16  A   2 (-3.4A)
None
P16  A   2 (-4.4A)
P16  A   2 (-3.5A)
0.64A 4u5jA-1opkA:
33.6
4u5jA-1opkA:
30.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q8y SR PROTEIN KINASE

(Saccharomyces
cerevisiae)
PF00069
(Pkinase)
8 LEU A 164
GLY A 167
VAL A 172
ALA A 185
ASN A 299
LEU A 301
ALA A 549
ASP A 550
ADP  A 810 ( 4.3A)
ADP  A 810 (-3.0A)
ADP  A 810 (-4.1A)
ADP  A 810 (-3.3A)
MG  A 809 ( 3.0A)
ADP  A 810 (-4.7A)
None
ADP  A 810 ( 3.0A)
0.63A 4u5jA-1q8yA:
24.1
4u5jA-1q8yA:
24.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1rjb FL CYTOKINE RECEPTOR

(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 LEU A 616
VAL A 624
ALA A 642
TYR A 693
GLY A 697
ASN A 816
LEU A 818
ASP A 829
None
0.70A 4u5jA-1rjbA:
30.3
4u5jA-1rjbA:
36.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zlt SERINE/THREONINE-PRO
TEIN KINASE CHK1


(Homo sapiens)
PF00069
(Pkinase)
8 LEU A  15
VAL A  23
ALA A  36
TYR A  86
GLY A  90
ASN A 135
LEU A 137
ASP A 148
HYM  A 400 (-4.2A)
HYM  A 400 (-4.3A)
HYM  A 400 (-3.5A)
HYM  A 400 (-4.7A)
None
HYM  A 400 (-4.2A)
HYM  A 400 (-4.5A)
HYM  A 400 (-3.9A)
0.56A 4u5jA-1zltA:
12.8
4u5jA-1zltA:
26.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2dq7 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE FYN


(Homo sapiens)
PF07714
(Pkinase_Tyr)
11 LEU X  17
GLY X  20
VAL X  25
ALA X  37
TYR X  84
MET X  85
GLY X  88
ASN X 135
LEU X 137
ALA X 147
ASP X 148
STU  X 902 (-3.8A)
None
STU  X 902 ( 4.8A)
STU  X 902 (-3.1A)
STU  X 902 (-4.6A)
None
STU  X 902 (-3.5A)
STU  X 902 ( 4.9A)
STU  X 902 (-4.4A)
STU  X 902 ( 4.1A)
STU  X 902 (-3.6A)
0.58A 4u5jA-2dq7X:
38.9
4u5jA-2dq7X:
84.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f9g MITOGEN-ACTIVATED
PROTEIN KINASE FUS3


(Saccharomyces
cerevisiae)
PF00069
(Pkinase)
8 LEU A  19
GLY A  22
VAL A  27
ALA A  40
MET A  96
ASN A 142
LEU A 144
ASP A 155
ADP  A 500 (-4.3A)
ADP  A 500 ( 4.6A)
ADP  A 500 (-4.3A)
ADP  A 500 ( 3.7A)
None
MG  A 600 ( 2.7A)
ADP  A 500 (-4.3A)
ADP  A 500 ( 2.9A)
0.65A 4u5jA-2f9gA:
15.7
4u5jA-2f9gA:
27.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gcd SERINE/THREONINE-PRO
TEIN KINASE TAO2


(Rattus
norvegicus)
PF00069
(Pkinase)
8 GLY A  37
VAL A  42
ALA A  55
TYR A 107
GLY A 110
ASN A 156
LEU A 158
ASP A 169
None
STU  A 400 ( 4.8A)
STU  A 400 (-3.2A)
STU  A 400 (-4.5A)
STU  A 400 (-3.4A)
STU  A 400 (-4.4A)
STU  A 400 ( 4.6A)
STU  A 400 (-3.6A)
0.70A 4u5jA-2gcdA:
27.7
4u5jA-2gcdA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2h8h PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC


(Homo sapiens)
PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr)
11 LEU A 273
GLY A 276
VAL A 281
ALA A 293
TYR A 340
MET A 341
GLY A 344
ASN A 391
LEU A 393
ALA A 403
ASP A 404
H8H  A 534 (-3.8A)
None
H8H  A 534 (-4.4A)
H8H  A 534 (-3.2A)
H8H  A 534 (-4.3A)
None
H8H  A 534 (-3.3A)
H8H  A 534 ( 4.9A)
H8H  A 534 (-4.5A)
H8H  A 534 ( 4.0A)
H8H  A 534 (-4.2A)
0.67A 4u5jA-2h8hA:
35.4
4u5jA-2h8hA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hck HEMATOPOETIC CELL
KINASE HCK


(Homo sapiens)
PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr)
9 LEU A 273
GLY A 276
VAL A 281
ALA A 293
MET A 341
GLY A 344
ASN A 391
LEU A 393
ALA A 403
QUE  A   1 (-3.9A)
None
QUE  A   1 ( 4.8A)
QUE  A   1 (-3.5A)
None
QUE  A   1 (-3.0A)
None
QUE  A   1 (-4.4A)
QUE  A   1 ( 4.5A)
0.64A 4u5jA-2hckA:
33.6
4u5jA-2hckA:
51.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hck HEMATOPOETIC CELL
KINASE HCK


(Homo sapiens)
PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr)
9 LEU A 273
GLY A 279
VAL A 281
ALA A 293
MET A 341
GLY A 344
ASN A 391
LEU A 393
ALA A 403
QUE  A   1 (-3.9A)
None
QUE  A   1 ( 4.8A)
QUE  A   1 (-3.5A)
None
QUE  A   1 (-3.0A)
None
QUE  A   1 (-4.4A)
QUE  A   1 ( 4.5A)
1.16A 4u5jA-2hckA:
33.6
4u5jA-2hckA:
51.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hk5 TYROSINE-PROTEIN
KINASE HCK


(Homo sapiens)
PF07714
(Pkinase_Tyr)
9 LEU A 251
VAL A 259
ALA A 271
MET A 319
GLY A 322
ASN A 369
LEU A 371
ALA A 381
ASP A 382
1BM  A 499 ( 3.7A)
1BM  A 499 ( 4.8A)
1BM  A 499 (-3.6A)
None
1BM  A 499 (-3.5A)
1BM  A 499 (-4.1A)
1BM  A 499 (-4.4A)
1BM  A 499 ( 3.7A)
1BM  A 499 (-4.4A)
0.50A 4u5jA-2hk5A:
30.2
4u5jA-2hk5A:
67.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hz0 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1


(Homo sapiens)
PF07714
(Pkinase_Tyr)
9 LEU A 248
GLY A 251
VAL A 256
ALA A 269
MET A 318
GLY A 321
LEU A 370
ALA A 380
ASP A 381
GIN  A 600 ( 4.6A)
None
GIN  A 600 ( 4.7A)
GIN  A 600 (-3.1A)
None
None
GIN  A 600 (-4.7A)
GIN  A 600 (-3.1A)
GIN  A 600 (-4.9A)
0.77A 4u5jA-2hz0A:
34.5
4u5jA-2hz0A:
48.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i0e PROTEIN KINASE
C-BETA II


(Homo sapiens)
PF00069
(Pkinase)
PF00433
(Pkinase_C)
8 LEU A 348
GLY A 351
VAL A 356
ALA A 369
TYR A 422
ASN A 471
ALA A 483
ASP A 484
PDS  A 901 (-3.9A)
None
PDS  A 901 (-4.2A)
PDS  A 901 (-3.3A)
PDS  A 901 (-4.7A)
PDS  A 901 (-4.3A)
PDS  A 901 (-3.4A)
PDS  A 901 (-3.6A)
0.70A 4u5jA-2i0eA:
14.5
4u5jA-2i0eA:
25.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ogv MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR
PRECURSOR


(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 LEU A 588
VAL A 596
ALA A 614
TYR A 665
GLY A 669
ASN A 783
LEU A 785
ASP A 796
None
0.56A 4u5jA-2ogvA:
30.0
4u5jA-2ogvA:
34.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2phk PHOSPHORYLASE KINASE

(Oryctolagus
cuniculus)
PF00069
(Pkinase)
9 LEU A  25
GLY A  28
VAL A  33
ALA A  46
MET A 106
GLY A 109
ASN A 154
LEU A 156
ASP A 167
ATP  A 381 ( 4.3A)
ATP  A 381 (-3.0A)
ATP  A 381 (-4.1A)
ATP  A 381 (-3.5A)
None
None
MN  A 383 ( 2.7A)
ATP  A 381 ( 4.8A)
MN  A 382 (-2.0A)
0.55A 4u5jA-2phkA:
18.6
4u5jA-2phkA:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pmo SER/THR PROTEIN
KINASE


(Plasmodium
falciparum)
PF00069
(Pkinase)
8 LEU X  34
GLY X  37
ALA X  53
TYR X 119
MET X 120
ASN X 177
LEU X 179
ASP X 190
HMD  X 400 ( 4.3A)
None
HMD  X 400 (-3.5A)
HMD  X 400 (-4.5A)
None
HMD  X 400 (-4.6A)
HMD  X 400 (-4.7A)
HMD  X 400 (-3.7A)
0.49A 4u5jA-2pmoX:
23.8
4u5jA-2pmoX:
23.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2psq FIBROBLAST GROWTH
FACTOR RECEPTOR 2


(Homo sapiens)
PF07714
(Pkinase_Tyr)
9 LEU A 487
GLY A 493
VAL A 495
ALA A 515
TYR A 566
GLY A 570
ASN A 631
LEU A 633
ALA A 643
None
0.85A 4u5jA-2psqA:
33.9
4u5jA-2psqA:
32.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qkw PROTEIN KINASE

(Solanum
pimpinellifolium)
PF07714
(Pkinase_Tyr)
9 GLY B  50
VAL B  55
ALA B  67
TYR B 116
MET B 117
GLY B 120
ASN B 169
LEU B 171
ASP B 182
None
0.54A 4u5jA-2qkwB:
26.5
4u5jA-2qkwB:
30.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2r2p EPHRIN TYPE-A
RECEPTOR 5


(Homo sapiens)
PF07714
(Pkinase_Tyr)
PF14575
(EphA2_TM)
8 VAL A 689
ALA A 705
TYR A 755
MET A 756
GLY A 759
ASN A 805
LEU A 807
ASP A 818
None
0.53A 4u5jA-2r2pA:
35.1
4u5jA-2r2pA:
43.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v55 RHO-ASSOCIATED
PROTEIN KINASE 1


(Homo sapiens)
PF00069
(Pkinase)
10 GLY A  85
VAL A  90
ALA A 103
TYR A 155
MET A 156
GLY A 159
ASN A 203
LEU A 205
ALA A 215
ASP A 216
ANP  A1480 ( 3.8A)
None
ANP  A1480 ( 3.9A)
ANP  A1480 ( 4.9A)
None
None
MG  A1481 (-3.5A)
ANP  A1480 ( 4.7A)
ANP  A1480 ( 4.1A)
ANP  A1480 (-3.5A)
0.72A 4u5jA-2v55A:
21.2
4u5jA-2v55A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vd5 DMPK PROTEIN

(Homo sapiens)
PF00069
(Pkinase)
8 GLY A  80
VAL A  85
ALA A  98
TYR A 150
ASN A 200
LEU A 202
ALA A 212
ASP A 213
None
BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-4.8A)
BI8  A1417 (-3.6A)
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
BI8  A1417 (-3.8A)
0.62A 4u5jA-2vd5A:
23.1
4u5jA-2vd5A:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xik SERINE/THREONINE
PROTEIN KINASE 25


(Homo sapiens)
PF00069
(Pkinase)
8 VAL A  34
ALA A  47
TYR A  97
GLY A 101
ASN A 145
LEU A 147
ALA A 157
ASP A 158
J60  A1294 ( 4.9A)
J60  A1294 (-3.3A)
J60  A1294 (-4.5A)
J60  A1294 ( 3.8A)
None
J60  A1294 (-4.8A)
J60  A1294 ( 4.2A)
J60  A1294 ( 4.6A)
0.49A 4u5jA-2xikA:
21.1
4u5jA-2xikA:
29.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xk9 CHECKPOINT KINASE 2

(Homo sapiens)
PF00069
(Pkinase)
8 LEU A 226
GLY A 229
VAL A 234
ALA A 247
MET A 304
GLY A 307
ASN A 352
LEU A 354
XK9  A1511 (-3.8A)
None
XK9  A1511 (-4.8A)
XK9  A1511 ( 4.1A)
None
XK9  A1511 ( 3.7A)
None
XK9  A1511 (-4.6A)
0.70A 4u5jA-2xk9A:
22.8
4u5jA-2xk9A:
28.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zv7 TYROSINE-PROTEIN
KINASE LYN


(Mus musculus)
PF07714
(Pkinase_Tyr)
9 LEU A 253
VAL A 261
ALA A 273
MET A 322
GLY A 325
ASN A 372
LEU A 374
ALA A 384
ASP A 385
None
0.51A 4u5jA-2zv7A:
37.6
4u5jA-2zv7A:
64.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3b2t FIBROBLAST GROWTH
FACTOR RECEPTOR 2


(Homo sapiens)
PF07714
(Pkinase_Tyr)
9 LEU A 487
GLY A 490
VAL A 495
ALA A 515
TYR A 566
GLY A 570
ASN A 631
LEU A 633
ALA A 643
M33  A1996 (-4.0A)
M33  A1996 (-3.0A)
M33  A1996 ( 4.7A)
M33  A1996 (-3.3A)
M33  A1996 ( 4.7A)
M33  A1996 ( 4.8A)
None
M33  A1996 (-4.5A)
None
0.45A 4u5jA-3b2tA:
26.1
4u5jA-3b2tA:
36.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3c4f BASIC FIBROBLAST
GROWTH FACTOR
RECEPTOR 1


(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 LEU A 484
VAL A 492
ALA A 512
TYR A 563
GLY A 567
ASN A 628
LEU A 630
ALA A 640
C4F  A   1 ( 3.9A)
None
C4F  A   1 (-3.3A)
None
None
None
C4F  A   1 (-4.6A)
C4F  A   1 (-3.6A)
0.65A 4u5jA-3c4fA:
30.6
4u5jA-3c4fA:
36.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3d7u TYROSINE-PROTEIN
KINASE CSK


(Homo sapiens)
PF07714
(Pkinase_Tyr)
9 GLY A 204
VAL A 209
ALA A 220
TYR A 268
MET A 269
GLY A 272
ASN A 319
LEU A 321
ASP A 332
None
0.41A 4u5jA-3d7uA:
28.4
4u5jA-3d7uA:
42.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3d7u TYROSINE-PROTEIN
KINASE CSK


(Homo sapiens)
PF07714
(Pkinase_Tyr)
9 GLY A 207
VAL A 209
ALA A 220
TYR A 268
MET A 269
GLY A 272
ASN A 319
LEU A 321
ASP A 332
None
1.02A 4u5jA-3d7uA:
28.4
4u5jA-3d7uA:
42.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iec SERINE/THREONINE-PRO
TEIN KINASE MARK2


(Homo sapiens)
PF00069
(Pkinase)
PF00627
(UBA)
8 VAL A  67
ALA A  80
TYR A 131
GLY A 135
ASN A 180
LEU A 182
ALA A 192
ASP A 193
None
0.74A 4u5jA-3iecA:
25.0
4u5jA-3iecA:
27.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kul EPHRIN TYPE-A
RECEPTOR 8


(Homo sapiens)
PF07714
(Pkinase_Tyr)
PF14575
(EphA2_TM)
8 VAL A 649
ALA A 665
TYR A 715
MET A 716
GLY A 719
ASN A 765
LEU A 767
ASP A 778
None
None
GOL  A 403 (-4.1A)
None
GOL  A 403 (-3.4A)
None
None
None
0.68A 4u5jA-3kulA:
28.9
4u5jA-3kulA:
38.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lm5 SERINE/THREONINE-PRO
TEIN KINASE 17B


(Homo sapiens)
PF00069
(Pkinase)
8 LEU A  39
GLY A  42
VAL A  47
ALA A  60
TYR A 112
GLY A 116
ASN A 163
LEU A 165
QUE  A   1 ( 3.8A)
None
QUE  A   1 ( 4.6A)
QUE  A   1 (-3.2A)
QUE  A   1 (-4.9A)
None
None
None
0.74A 4u5jA-3lm5A:
26.8
4u5jA-3lm5A:
27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mvj CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA


(Homo sapiens)
PF00069
(Pkinase)
9 LEU A  49
GLY A  52
VAL A  57
ALA A  70
TYR A 122
GLY A 126
ASN A 171
LEU A 173
ASP A 184
XFE  A 351 (-4.2A)
None
XFE  A 351 ( 4.5A)
XFE  A 351 (-3.2A)
None
None
None
XFE  A 351 (-4.6A)
None
0.86A 4u5jA-3mvjA:
24.3
4u5jA-3mvjA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3


(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 VAL A 216
ALA A 227
TYR A 279
GLY A 283
ASN A 335
LEU A 337
ALA A 347
ASP A 348
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.5A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
0.72A 4u5jA-3my0A:
27.6
4u5jA-3my0A:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3niz RHODANESE FAMILY
PROTEIN


(Cryptosporidium
parvum)
PF00069
(Pkinase)
8 GLY A  32
VAL A  37
ALA A  49
MET A 101
ASN A 149
LEU A 151
ALA A 161
ASP A 162
ADP  A 314 (-3.0A)
ADP  A 314 (-4.0A)
ADP  A 314 (-3.5A)
None
MG  A 312 ( 2.9A)
ADP  A 314 (-4.6A)
None
MG  A 312 ( 3.3A)
0.48A 4u5jA-3nizA:
26.6
4u5jA-3nizA:
25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nuu PKB-LIKE

(Homo sapiens)
PF00069
(Pkinase)
9 LEU A  88
GLY A  91
VAL A  96
ALA A 109
TYR A 161
GLY A 165
ASN A 210
LEU A 212
ASP A 223
JOZ  A 361 (-4.1A)
SO4  A   5 ( 4.4A)
JOZ  A 361 ( 4.7A)
JOZ  A 361 (-3.4A)
None
None
None
None
SO4  A   5 ( 4.5A)
0.77A 4u5jA-3nuuA:
26.2
4u5jA-3nuuA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nyo G PROTEIN-COUPLED
RECEPTOR KINASE 6


(Homo sapiens)
PF00069
(Pkinase)
PF00615
(RGS)
8 LEU A 192
VAL A 200
ALA A 213
MET A 266
GLY A 269
ASN A 316
LEU A 318
ASP A 329
AMP  A 577 ( 4.3A)
AMP  A 577 (-4.3A)
AMP  A 577 (-3.4A)
None
None
AMP  A 577 (-4.2A)
AMP  A 577 (-4.8A)
AMP  A 577 (-4.0A)
0.50A 4u5jA-3nyoA:
18.2
4u5jA-3nyoA:
22.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3pls MACROPHAGE-STIMULATI
NG PROTEIN RECEPTOR


(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 GLY A1091
VAL A1096
ALA A1112
TYR A1163
MET A1164
GLY A1167
ASN A1213
ALA A1225
ANP  A1358 (-3.4A)
ANP  A1358 (-4.4A)
ANP  A1358 ( 3.8A)
ANP  A1358 (-4.3A)
None
None
MG  A   1 ( 2.9A)
None
0.67A 4u5jA-3plsA:
30.4
4u5jA-3plsA:
37.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ppz SERINE/THREONINE-PRO
TEIN KINASE CTR1


(Arabidopsis
thaliana)
PF07714
(Pkinase_Tyr)
8 GLY A 560
VAL A 565
ALA A 576
TYR A 627
GLY A 631
ASN A 681
LEU A 683
ASP A 694
None
STU  A   1 (-4.9A)
STU  A   1 (-3.3A)
STU  A   1 (-4.4A)
STU  A   1 (-3.2A)
STU  A   1 (-4.6A)
STU  A   1 (-4.3A)
STU  A   1 (-3.5A)
0.45A 4u5jA-3ppzA:
32.3
4u5jA-3ppzA:
32.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tt0 BASIC FIBROBLAST
GROWTH FACTOR
RECEPTOR 1


(Homo sapiens)
PF07714
(Pkinase_Tyr)
9 LEU A 484
GLY A 487
VAL A 492
ALA A 512
TYR A 563
GLY A 567
ASN A 628
LEU A 630
ALA A 640
07J  A   1 ( 4.3A)
None
07J  A   1 (-4.0A)
07J  A   1 (-3.5A)
07J  A   1 (-4.7A)
07J  A   1 (-3.7A)
None
07J  A   1 ( 4.4A)
07J  A   1 (-3.2A)
0.75A 4u5jA-3tt0A:
30.7
4u5jA-3tt0A:
33.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3txo PROTEIN KINASE C ETA
TYPE


(Homo sapiens)
PF00069
(Pkinase)
PF00433
(Pkinase_C)
8 LEU A 361
GLY A 364
VAL A 369
ALA A 382
ASN A 484
LEU A 486
ALA A 496
ASP A 497
07U  A   1 ( 4.8A)
None
07U  A   1 (-4.8A)
07U  A   1 (-3.3A)
None
07U  A   1 (-4.3A)
07U  A   1 ( 4.0A)
07U  A   1 (-3.6A)
0.71A 4u5jA-3txoA:
15.4
4u5jA-3txoA:
24.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3v5q NT-3 GROWTH FACTOR
RECEPTOR


(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 LEU A 544
VAL A 552
ALA A 570
TYR A 619
MET A 620
GLY A 623
ASN A 684
LEU A 686
0F4  A 902 ( 4.2A)
None
0F4  A 902 (-3.2A)
0F4  A 902 (-4.2A)
None
0F4  A 902 (-3.4A)
None
0F4  A 902 (-4.5A)
0.50A 4u5jA-3v5qA:
25.3
4u5jA-3v5qA:
34.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w18 AURORA KINASE A

(Homo sapiens)
PF00069
(Pkinase)
8 LEU A 139
GLY A 142
VAL A 147
ALA A 160
TYR A 212
ASN A 261
LEU A 263
ALA A 273
N13  A 501 (-3.7A)
None
N13  A 501 ( 4.7A)
N13  A 501 ( 4.1A)
N13  A 501 (-4.4A)
None
N13  A 501 (-4.5A)
N13  A 501 ( 3.8A)
0.57A 4u5jA-3w18A:
16.8
4u5jA-3w18A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w18 AURORA KINASE A

(Homo sapiens)
PF00069
(Pkinase)
8 LEU A 139
VAL A 147
ALA A 160
TYR A 212
GLY A 216
ASN A 261
LEU A 263
ALA A 273
N13  A 501 (-3.7A)
N13  A 501 ( 4.7A)
N13  A 501 ( 4.1A)
N13  A 501 (-4.4A)
N13  A 501 (-3.5A)
None
N13  A 501 (-4.5A)
N13  A 501 ( 3.8A)
0.59A 4u5jA-3w18A:
16.8
4u5jA-3w18A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wig DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1


(Homo sapiens)
PF00069
(Pkinase)
8 LEU A  75
GLY A  78
VAL A  83
ALA A  96
MET A 147
GLY A 150
ASN A 196
LEU A 198
ANP  A 401 (-3.8A)
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
ANP  A 401 (-3.2A)
None
ANP  A 401 ( 4.3A)
MG  A 402 ( 2.9A)
ANP  A 401 (-4.8A)
0.74A 4u5jA-3wigA:
23.3
4u5jA-3wigA:
27.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3zbf PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ROS


(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 LEU A1951
VAL A1959
ALA A1978
MET A2029
GLY A2032
ASN A2084
LEU A2086
ASP A2102
VGH  A3000 ( 4.4A)
None
VGH  A3000 (-3.4A)
None
VGH  A3000 (-3.5A)
None
VGH  A3000 (-4.3A)
None
0.65A 4u5jA-3zbfA:
26.2
4u5jA-3zbfA:
40.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4af3 AURORA KINASE B

(Homo sapiens)
PF00069
(Pkinase)
8 LEU A  83
VAL A  91
ALA A 104
TYR A 156
GLY A 160
ASN A 205
LEU A 207
ALA A 217
VX6  A 500 (-3.8A)
VX6  A 500 ( 4.8A)
VX6  A 500 (-3.4A)
VX6  A 500 (-4.2A)
VX6  A 500 (-3.3A)
None
VX6  A 500 (-4.6A)
VX6  A 500 ( 4.2A)
0.64A 4u5jA-4af3A:
20.6
4u5jA-4af3A:
23.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4at3 BDNF/NT-3 GROWTH
FACTORS RECEPTOR


(Homo sapiens)
PF07714
(Pkinase_Tyr)
9 LEU A 560
VAL A 568
ALA A 586
TYR A 635
MET A 636
GLY A 639
ASN A 697
LEU A 699
ASP A 710
LTI  A1839 ( 4.2A)
None
LTI  A1839 (-3.3A)
LTI  A1839 (-4.7A)
None
LTI  A1839 (-3.4A)
None
LTI  A1839 (-4.2A)
None
0.60A 4u5jA-4at3A:
30.2
4u5jA-4at3A:
33.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aw2 SERINE/THREONINE-PRO
TEIN KINASE MRCK
ALPHA


(Rattus
norvegicus)
PF00069
(Pkinase)
PF00433
(Pkinase_C)
8 GLY A  86
VAL A  91
ALA A 104
TYR A 156
ASN A 206
LEU A 208
ALA A 218
ASP A 219
None
None
EDO  A1420 (-3.4A)
EDO  A1420 (-4.9A)
None
EDO  A1420 ( 4.8A)
None
None
0.73A 4u5jA-4aw2A:
22.6
4u5jA-4aw2A:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c02 ACTIVIN RECEPTOR
TYPE-1


(Homo sapiens)
PF00069
(Pkinase)
PF08515
(TGF_beta_GS)
8 GLY A 217
VAL A 222
ALA A 233
TYR A 285
GLY A 289
ASN A 341
LEU A 343
ALA A 353
None
TAK  A1507 (-4.7A)
TAK  A1507 (-3.3A)
TAK  A1507 ( 4.6A)
TAK  A1507 (-3.5A)
None
TAK  A1507 (-4.7A)
TAK  A1507 ( 4.2A)
0.69A 4u5jA-4c02A:
27.6
4u5jA-4c02A:
28.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cfh 5'-AMP-ACTIVATED
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA-1


(Rattus
norvegicus)
PF00069
(Pkinase)
PF16579
(AdenylateSensor)
8 LEU A  22
VAL A  30
ALA A  43
TYR A  95
GLY A  99
ASN A 144
LEU A 146
ALA A 156
STU  A1550 (-4.3A)
None
STU  A1550 (-3.1A)
STU  A1550 (-4.5A)
STU  A1550 (-3.4A)
STU  A1550 (-4.3A)
STU  A1550 (-4.3A)
STU  A1550 ( 3.8A)
0.69A 4u5jA-4cfhA:
25.8
4u5jA-4cfhA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cfh 5'-AMP-ACTIVATED
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA-1


(Rattus
norvegicus)
PF00069
(Pkinase)
PF16579
(AdenylateSensor)
8 VAL A  30
ALA A  43
TYR A  95
GLY A  99
ASN A 144
LEU A 146
ALA A 156
ASP A 157
None
STU  A1550 (-3.1A)
STU  A1550 (-4.5A)
STU  A1550 (-3.4A)
STU  A1550 (-4.3A)
STU  A1550 (-4.3A)
STU  A1550 ( 3.8A)
STU  A1550 (-3.6A)
0.67A 4u5jA-4cfhA:
25.8
4u5jA-4cfhA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4crs SERINE/THREONINE-PRO
TEIN KINASE N2


(Homo sapiens)
PF00069
(Pkinase)
PF00433
(Pkinase_C)
8 LEU A 663
GLY A 666
VAL A 671
ALA A 684
TYR A 739
GLY A 743
LEU A 789
ASP A 800
AGS  A1985 (-4.2A)
AGS  A1985 (-2.9A)
AGS  A1985 (-4.6A)
AGS  A1985 (-3.5A)
None
None
AGS  A1985 (-4.8A)
AGS  A1985 ( 3.3A)
0.70A 4u5jA-4crsA:
17.9
4u5jA-4crsA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4crs SERINE/THREONINE-PRO
TEIN KINASE N2


(Homo sapiens)
PF00069
(Pkinase)
PF00433
(Pkinase_C)
9 LEU A 663
VAL A 671
ALA A 684
TYR A 739
GLY A 743
ASN A 787
LEU A 789
ALA A 799
ASP A 800
AGS  A1985 (-4.2A)
AGS  A1985 (-4.6A)
AGS  A1985 (-3.5A)
None
None
MG  A1986 ( 3.2A)
AGS  A1985 (-4.8A)
AGS  A1985 ( 4.5A)
AGS  A1985 ( 3.3A)
0.56A 4u5jA-4crsA:
17.9
4u5jA-4crsA:
24.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4f0i HIGH AFFINITY NERVE
GROWTH FACTOR
RECEPTOR


(Homo sapiens)
PF07714
(Pkinase_Tyr)
9 LEU A 515
VAL A 523
ALA A 541
TYR A 590
MET A 591
GLY A 594
ASN A 654
LEU A 656
ASP A 667
None
0.77A 4u5jA-4f0iA:
24.5
4u5jA-4f0iA:
33.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4fod ALK TYROSINE KINASE
RECEPTOR


(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 LEU A1122
VAL A1130
ALA A1148
MET A1199
GLY A1202
ASN A1254
LEU A1256
ASP A1270
0UV  A1501 (-3.8A)
0UV  A1501 (-4.5A)
0UV  A1501 (-3.4A)
None
0UV  A1501 (-3.6A)
0UV  A1501 ( 4.9A)
0UV  A1501 (-4.6A)
0UV  A1501 ( 4.2A)
0.48A 4u5jA-4fodA:
25.6
4u5jA-4fodA:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gl9 TYROSINE-PROTEIN
KINASE


(Mus musculus)
PF07714
(Pkinase_Tyr)
9 LEU A 855
GLY A 861
VAL A 863
ALA A 880
TYR A 931
GLY A 935
ASN A 981
LEU A 983
ASP A 994
IZA  A2001 (-3.7A)
None
None
IZA  A2001 (-3.4A)
None
IZA  A2001 (-3.3A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.7A)
IZA  A2001 ( 4.5A)
1.28A 4u5jA-4gl9A:
31.3
4u5jA-4gl9A:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hvi TYROSINE-PROTEIN
KINASE JAK3


(Homo sapiens)
PF07714
(Pkinase_Tyr)
10 LEU A 828
GLY A 831
VAL A 836
ALA A 853
TYR A 904
GLY A 908
ASN A 954
LEU A 956
ALA A 966
ASP A 967
19S  A1201 (-3.9A)
19S  A1201 ( 4.3A)
19S  A1201 (-4.4A)
19S  A1201 (-3.3A)
19S  A1201 (-4.7A)
19S  A1201 ( 3.8A)
None
19S  A1201 (-4.5A)
19S  A1201 ( 4.1A)
19S  A1201 ( 4.1A)
0.73A 4u5jA-4hviA:
26.1
4u5jA-4hviA:
33.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hvi TYROSINE-PROTEIN
KINASE JAK3


(Homo sapiens)
PF07714
(Pkinase_Tyr)
9 LEU A 828
GLY A 834
VAL A 836
ALA A 853
TYR A 904
ASN A 954
LEU A 956
ALA A 966
ASP A 967
19S  A1201 (-3.9A)
19S  A1201 ( 4.9A)
19S  A1201 (-4.4A)
19S  A1201 (-3.3A)
19S  A1201 (-4.7A)
None
19S  A1201 (-4.5A)
19S  A1201 ( 4.1A)
19S  A1201 ( 4.1A)
1.25A 4u5jA-4hviA:
26.1
4u5jA-4hviA:
33.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4id7 ACTIVATED CDC42
KINASE 1


(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 LEU A 132
GLY A 135
VAL A 140
ALA A 156
GLY A 211
ASN A 257
LEU A 259
ASP A 270
1G0  A 401 ( 4.5A)
None
1G0  A 401 (-4.4A)
1G0  A 401 (-3.6A)
1G0  A 401 ( 4.5A)
None
1G0  A 401 (-4.6A)
None
0.67A 4u5jA-4id7A:
32.7
4u5jA-4id7A:
39.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4k11 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC


(Homo sapiens)
PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr)
10 LEU A 273
GLY A 276
VAL A 281
ALA A 293
TYR A 340
MET A 341
GLY A 344
ASN A 391
LEU A 393
ALA A 403
0J9  A 601 (-4.0A)
None
0J9  A 601 (-4.4A)
0J9  A 601 (-3.3A)
0J9  A 601 ( 4.7A)
None
0J9  A 601 ( 4.1A)
None
0J9  A 601 (-4.5A)
0J9  A 601 (-3.5A)
0.49A 4u5jA-4k11A:
35.1
4u5jA-4k11A:
94.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4k11 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC


(Homo sapiens)
PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr)
9 LEU A 273
GLY A 279
VAL A 281
ALA A 293
TYR A 340
MET A 341
ASN A 391
LEU A 393
ALA A 403
0J9  A 601 (-4.0A)
None
0J9  A 601 (-4.4A)
0J9  A 601 (-3.3A)
0J9  A 601 ( 4.7A)
None
None
0J9  A 601 (-4.5A)
0J9  A 601 (-3.5A)
1.03A 4u5jA-4k11A:
35.1
4u5jA-4k11A:
94.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3


(Homo sapiens)
PF07714
(Pkinase_Tyr)
10 LEU A 478
GLY A 481
VAL A 486
ALA A 506
TYR A 557
GLY A 561
ASN A 622
LEU A 624
ALA A 634
ASP A 635
ACP  A 801 (-3.8A)
ACP  A 801 (-3.6A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 ( 4.6A)
MG  A 802 ( 2.4A)
ACP  A 801 (-4.4A)
None
MG  A 802 ( 3.0A)
0.60A 4u5jA-4k33A:
26.9
4u5jA-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3


(Homo sapiens)
PF07714
(Pkinase_Tyr)
10 LEU A 478
GLY A 484
VAL A 486
ALA A 506
TYR A 557
GLY A 561
ASN A 622
LEU A 624
ALA A 634
ASP A 635
ACP  A 801 (-3.8A)
ACP  A 801 (-3.6A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
None
ACP  A 801 ( 4.6A)
MG  A 802 ( 2.4A)
ACP  A 801 (-4.4A)
None
MG  A 802 ( 3.0A)
0.86A 4u5jA-4k33A:
26.9
4u5jA-4k33A:
35.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4lgg PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC


(Gallus gallus)
PF07714
(Pkinase_Tyr)
9 LEU A 273
GLY A 276
VAL A 281
ALA A 293
TYR A 340
MET A 341
GLY A 344
ASN A 391
LEU A 393
VGG  A 601 (-3.2A)
None
VGG  A 601 ( 3.5A)
VGG  A 601 (-3.5A)
VGG  A 601 ( 4.0A)
None
VGG  A 601 ( 3.2A)
None
VGG  A 601 (-4.5A)
0.56A 4u5jA-4lggA:
37.9
4u5jA-4lggA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4lgg PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC


(Gallus gallus)
PF07714
(Pkinase_Tyr)
9 LEU A 273
VAL A 281
ALA A 293
TYR A 340
MET A 341
GLY A 344
ASN A 391
LEU A 393
ALA A 403
VGG  A 601 (-3.2A)
VGG  A 601 ( 3.5A)
VGG  A 601 (-3.5A)
VGG  A 601 ( 4.0A)
None
VGG  A 601 ( 3.2A)
None
VGG  A 601 (-4.5A)
VGG  A 601 ( 4.2A)
0.43A 4u5jA-4lggA:
37.9
4u5jA-4lggA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4o27 SERINE/THREONINE-PRO
TEIN KINASE 24


(Homo sapiens)
PF00069
(Pkinase)
9 GLY B  33
VAL B  38
ALA B  51
TYR B 101
GLY B 105
ASN B 149
LEU B 151
ALA B 161
ASP B 162
ADP  B 500 (-3.3A)
ADP  B 500 (-4.5A)
ADP  B 500 (-3.3A)
ADP  B 500 ( 4.7A)
None
MN  B 501 ( 3.1A)
ADP  B 500 (-4.7A)
None
ADP  B 500 ( 3.4A)
0.60A 4u5jA-4o27B:
20.5
4u5jA-4o27B:
30.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4otd SERINE/THREONINE-PRO
TEIN KINASE N1


(Homo sapiens)
PF00069
(Pkinase)
PF00433
(Pkinase_C)
10 LEU A 627
GLY A 630
VAL A 635
ALA A 648
TYR A 703
GLY A 707
ASN A 751
LEU A 753
ALA A 763
ASP A 764
None
0.89A 4u5jA-4otdA:
24.3
4u5jA-4otdA:
26.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q9z HUMAN PROTEIN KINASE
C THETA


(Homo sapiens)
PF00069
(Pkinase)
PF00433
(Pkinase_C)
8 LEU A 386
GLY A 389
VAL A 394
ALA A 407
TYR A 460
ASN A 509
LEU A 511
ALA A 521
PZW  A 801 (-3.9A)
None
PZW  A 801 (-4.6A)
PZW  A 801 (-3.5A)
None
PZW  A 801 (-4.4A)
PZW  A 801 (-4.8A)
PZW  A 801 ( 4.6A)
0.54A 4u5jA-4q9zA:
23.0
4u5jA-4q9zA:
24.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4rt7 RECEPTOR-TYPE
TYROSINE-PROTEIN
KINASE FLT3


(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 LEU A 616
VAL A 624
ALA A 642
TYR A 693
GLY A 697
ASN A 816
LEU A 818
ASP A 829
P30  A1001 (-3.8A)
None
P30  A1001 (-3.4A)
P30  A1001 (-4.1A)
P30  A1001 (-3.4A)
None
P30  A1001 (-4.6A)
None
0.66A 4u5jA-4rt7A:
24.8
4u5jA-4rt7A:
32.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ueu TYROSINE KINASE AS -
A COMMON ANCESTOR OF
SRC AND ABL


(synthetic
construct)
PF07714
(Pkinase_Tyr)
10 LEU A  14
VAL A  22
ALA A  35
TYR A  83
MET A  84
GLY A  87
ASN A 134
LEU A 136
ALA A 146
ASP A 147
ACP  A1264 ( 4.5A)
ACP  A1264 (-4.7A)
ACP  A1264 (-2.9A)
ACP  A1264 ( 4.5A)
None
ACP  A1264 (-3.5A)
None
ACP  A1264 ( 4.8A)
None
None
0.53A 4u5jA-4ueuA:
36.6
4u5jA-4ueuA:
62.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wb7 DNAJ HOMOLOG
SUBFAMILY B MEMBER
1,CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA


(Homo sapiens)
PF00069
(Pkinase)
PF00226
(DnaJ)
8 LEU A 104
GLY A 107
VAL A 112
ALA A 125
TYR A 177
GLY A 181
LEU A 228
ASP A 239
ATP  A 501 ( 4.3A)
ATP  A 501 (-3.2A)
ATP  A 501 (-4.0A)
ATP  A 501 (-3.4A)
None
None
ATP  A 501 (-4.5A)
ZN  A 503 (-1.9A)
0.75A 4u5jA-4wb7A:
24.3
4u5jA-4wb7A:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wb7 DNAJ HOMOLOG
SUBFAMILY B MEMBER
1,CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA


(Homo sapiens)
PF00069
(Pkinase)
PF00226
(DnaJ)
8 LEU A 104
VAL A 112
ALA A 125
TYR A 177
GLY A 181
ASN A 226
LEU A 228
ASP A 239
ATP  A 501 ( 4.3A)
ATP  A 501 (-4.0A)
ATP  A 501 (-3.4A)
None
None
ZN  A 502 ( 2.5A)
ATP  A 501 (-4.5A)
ZN  A 503 (-1.9A)
0.69A 4u5jA-4wb7A:
24.3
4u5jA-4wb7A:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbo RHODOPSIN KINASE

(Bos taurus)
PF00069
(Pkinase)
PF00615
(RGS)
9 LEU A 193
GLY A 196
VAL A 201
ALA A 214
MET A 267
GLY A 270
ASN A 319
LEU A 321
ASP A 332
ANW  A 601 ( 4.0A)
None
None
ANW  A 601 (-3.4A)
None
ANW  A 601 ( 4.5A)
None
ANW  A 601 (-4.9A)
None
0.67A 4u5jA-4wboA:
25.2
4u5jA-4wboA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wsq AP2-ASSOCIATED
PROTEIN KINASE 1


(Homo sapiens)
PF00069
(Pkinase)
8 LEU A  52
GLY A  55
VAL A  60
ALA A  72
GLY A 132
ASN A 181
LEU A 183
ASP A 194
KSA  A 405 ( 4.0A)
KSA  A 405 ( 4.9A)
KSA  A 405 ( 4.9A)
KSA  A 405 (-3.2A)
KSA  A 405 (-3.5A)
KSA  A 405 (-4.0A)
KSA  A 405 (-4.6A)
ZN  A 403 ( 2.6A)
0.71A 4u5jA-4wsqA:
25.5
4u5jA-4wsqA:
26.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xey TYROSINE-PROTEIN
KINASE ABL1


(Homo sapiens)
no annotation 8 LEU B 267
VAL B 275
ALA B 288
MET B 337
GLY B 340
ASN B 387
LEU B 389
ALA B 399
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
None
1N1  B 601 (-3.5A)
None
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
0.53A 4u5jA-4xeyB:
34.3
4u5jA-4xeyB:
36.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xi2 TYROSINE-PROTEIN
KINASE BTK


(Mus musculus)
PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr)
8 LEU A 408
VAL A 416
ALA A 428
TYR A 476
MET A 477
GLY A 480
ASN A 526
LEU A 528
None
0.69A 4u5jA-4xi2A:
24.4
4u5jA-4xi2A:
28.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xuf RECEPTOR-TYPE
TYROSINE-PROTEIN
KINASE FLT3


(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 LEU A 616
GLY A 619
VAL A 624
ALA A 642
TYR A 693
GLY A 697
ASN A 816
LEU A 818
P30  A1001 (-4.0A)
None
P30  A1001 ( 4.8A)
P30  A1001 (-3.5A)
P30  A1001 ( 4.4A)
P30  A1001 (-3.5A)
None
P30  A1001 (-4.3A)
0.64A 4u5jA-4xufA:
30.7
4u5jA-4xufA:
38.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y93 NON-SPECIFIC
PROTEIN-TYROSINE
KINASE,NON-SPECIFIC
PROTEIN-TYROSINE
KINASE


(Bos taurus)
PF00169
(PH)
PF00779
(BTK)
PF07714
(Pkinase_Tyr)
8 LEU A 408
VAL A 416
ALA A 428
TYR A 476
MET A 477
GLY A 480
ASN A 526
LEU A 528
746  A 702 (-3.8A)
746  A 702 ( 4.3A)
746  A 702 (-2.4A)
746  A 702 (-4.4A)
None
746  A 702 (-3.6A)
746  A 702 (-2.8A)
746  A 702 (-4.4A)
0.32A 4u5jA-4y93A:
32.2
4u5jA-4y93A:
26.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5a46 FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B


(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 LEU A 484
VAL A 492
ALA A 512
TYR A 563
GLY A 567
ASN A 628
LEU A 630
ALA A 640
38O  A1769 (-3.2A)
38O  A1769 (-4.5A)
38O  A1769 (-3.6A)
38O  A1769 (-4.2A)
38O  A1769 (-3.4A)
None
38O  A1769 (-4.6A)
EDO  A1766 ( 4.4A)
0.49A 4u5jA-5a46A:
31.2
4u5jA-5a46A:
32.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ci7 SERINE/THREONINE-PRO
TEIN KINASE ULK1


(Homo sapiens)
PF00069
(Pkinase)
8 GLY A  25
VAL A  30
ALA A  44
TYR A  94
GLY A  98
ASN A 143
LEU A 145
ALA A 164
GOL  A 404 ( 3.2A)
51W  A 401 ( 4.3A)
51W  A 401 (-3.4A)
51W  A 401 ( 3.4A)
51W  A 401 (-3.7A)
GOL  A 404 ( 4.6A)
51W  A 401 (-4.5A)
None
0.57A 4u5jA-5ci7A:
27.1
4u5jA-5ci7A:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5es1 MAP/MICROTUBULE
AFFINITY-REGULATING
KINASE 4


(Homo sapiens)
PF00069
(Pkinase)
PF00627
(UBA)
9 GLY A  65
VAL A  70
ALA A  83
TYR A 134
GLY A 138
ASN A 183
LEU A 185
ALA A 195
ASP A 196
5RC  A4000 ( 3.9A)
5RC  A4000 (-4.6A)
5RC  A4000 (-3.6A)
5RC  A4000 (-4.5A)
5RC  A4000 (-3.3A)
5RC  A4000 (-4.1A)
None
5RC  A4000 ( 3.9A)
5RC  A4000 (-3.6A)
0.85A 4u5jA-5es1A:
25.0
4u5jA-5es1A:
29.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5fm2 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET


(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 LEU A 730
GLY A 733
VAL A 738
ALA A 756
TYR A 806
GLY A 810
ASN A 879
LEU A 881
PP1  A2012 (-4.6A)
None
PP1  A2012 (-4.4A)
PP1  A2012 (-3.2A)
None
PTR  A 809 (-2.4A)
None
PP1  A2012 (-4.6A)
0.62A 4u5jA-5fm2A:
34.5
4u5jA-5fm2A:
31.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hu3 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II ALPHA
CHAIN


(Drosophila
melanogaster)
PF00069
(Pkinase)
8 LEU A  20
VAL A  28
ALA A  41
GLY A  96
ASN A 141
LEU A 143
ALA A 156
ASP A 157
ADP  A 301 ( 4.0A)
ADP  A 301 (-3.7A)
ADP  A 301 (-3.5A)
None
MG  A 302 ( 2.8A)
ADP  A 301 (-4.7A)
ADP  A 301 ( 4.8A)
MG  A 302 ( 3.3A)
0.55A 4u5jA-5hu3A:
26.8
4u5jA-5hu3A:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i3o BMP-2-INDUCIBLE
PROTEIN KINASE


(Homo sapiens)
PF00069
(Pkinase)
8 LEU A  57
GLY A  60
VAL A  65
ALA A  77
TYR A 132
GLY A 136
LEU A 187
ASP A 198
IDV  A 401 (-3.8A)
IDV  A 401 (-3.5A)
IDV  A 401 (-4.6A)
IDV  A 401 (-3.6A)
IDV  A 401 (-3.5A)
IDV  A 401 (-3.4A)
IDV  A 401 (-4.4A)
IDV  A 401 (-4.0A)
0.75A 4u5jA-5i3oA:
24.9
4u5jA-5i3oA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i3o BMP-2-INDUCIBLE
PROTEIN KINASE


(Homo sapiens)
PF00069
(Pkinase)
8 LEU A  57
VAL A  65
ALA A  77
TYR A 132
GLY A 136
ASN A 185
LEU A 187
ASP A 198
IDV  A 401 (-3.8A)
IDV  A 401 (-4.6A)
IDV  A 401 (-3.6A)
IDV  A 401 (-3.5A)
IDV  A 401 (-3.4A)
IDV  A 401 (-4.1A)
IDV  A 401 (-4.4A)
IDV  A 401 (-4.0A)
0.76A 4u5jA-5i3oA:
24.9
4u5jA-5i3oA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iso 5'-AMP-ACTIVATED
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA-2


(Homo sapiens)
PF00069
(Pkinase)
PF16579
(AdenylateSensor)
9 LEU A  22
VAL A  30
ALA A  43
TYR A  95
GLY A  99
ASN A 144
LEU A 146
ALA A 156
ASP A 157
STU  A 601 (-4.1A)
STU  A 601 (-4.8A)
STU  A 601 (-3.3A)
STU  A 601 (-4.3A)
STU  A 601 ( 4.0A)
STU  A 601 (-4.3A)
STU  A 601 (-4.5A)
STU  A 601 (-3.5A)
STU  A 601 (-3.5A)
0.95A 4u5jA-5isoA:
25.1
4u5jA-5isoA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kbr SERINE/THREONINE-PRO
TEIN KINASE PAK 1


(Homo sapiens)
PF00069
(Pkinase)
8 GLY A 279
VAL A 284
ALA A 297
TYR A 346
GLY A 350
ASN A 394
LEU A 396
ASP A 407
None
IPW  A 601 (-4.2A)
IPW  A 601 (-3.5A)
IPW  A 601 (-4.5A)
IPW  A 601 ( 3.8A)
None
IPW  A 601 (-4.5A)
None
0.53A 4u5jA-5kbrA:
24.6
4u5jA-5kbrA:
26.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5td2 TYROSINE-PROTEIN
KINASE MER


(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 LEU A 593
VAL A 601
ALA A 617
MET A 674
GLY A 677
ASN A 728
ALA A 740
ASP A 741
7AE  A1000 ( 3.9A)
7AE  A1000 ( 4.9A)
7AE  A1000 (-3.3A)
None
7AE  A1000 ( 3.7A)
7AE  A1000 (-4.7A)
7AE  A1000 ( 3.7A)
7AE  A1000 (-4.4A)
0.54A 4u5jA-5td2A:
21.7
4u5jA-5td2A:
38.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tvt MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE


(Homo sapiens)
no annotation 8 GLY A  20
VAL A  25
ALA A  38
TYR A  88
GLY A  92
ASN A 137
LEU A 139
ASP A 150
7LV  A 401 ( 3.9A)
7LV  A 401 ( 4.6A)
7LV  A 401 (-3.4A)
7LV  A 401 (-4.6A)
None
None
7LV  A 401 (-4.9A)
7LV  A 401 (-4.2A)
0.73A 4u5jA-5tvtA:
19.4
4u5jA-5tvtA:
26.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5u6b TYROSINE-PROTEIN
KINASE RECEPTOR UFO


(Homo sapiens)
PF07714
(Pkinase_Tyr)
8 LEU A 542
VAL A 550
ALA A 565
MET A 623
GLY A 626
ASN A 677
ALA A 689
ASP A 690
7YS  A9001 (-4.1A)
7YS  A9001 (-4.2A)
7YS  A9001 (-3.3A)
7YS  A9001 (-4.7A)
7YS  A9001 (-3.4A)
None
7YS  A9001 (-3.4A)
None
0.67A 4u5jA-5u6bA:
30.9
4u5jA-5u6bA:
37.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7q RHO-ASSOCIATED
PROTEIN KINASE 2


(Homo sapiens)
PF00069
(Pkinase)
10 GLY A 101
VAL A 106
ALA A 119
TYR A 171
MET A 172
GLY A 175
ASN A 219
LEU A 221
ALA A 231
ASP A 232
None
0.52A 4u5jA-5u7qA:
22.0
4u5jA-5u7qA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uuu BETA-ADRENERGIC
RECEPTOR KINASE 1


(Homo sapiens)
PF00069
(Pkinase)
PF00615
(RGS)
8 GLY A 200
VAL A 205
ALA A 218
MET A 274
GLY A 277
ASN A 322
LEU A 324
ASP A 335
QRW  A 601 (-3.6A)
QRW  A 601 (-4.7A)
QRW  A 601 (-3.4A)
MES  A 604 (-3.9A)
None
None
None
QRW  A 601 (-3.7A)
0.68A 4u5jA-5uuuA:
24.9
4u5jA-5uuuA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w5j RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2


(Homo sapiens)
no annotation 9 LEU A  24
VAL A  32
ALA A  45
TYR A  97
MET A  98
GLY A 101
ASN A 151
LEU A 153
ALA A 163
9WS  A 401 ( 4.2A)
9WS  A 401 ( 4.6A)
9WS  A 401 (-3.3A)
None
None
9WS  A 401 ( 4.3A)
None
9WS  A 401 (-4.6A)
9WS  A 401 ( 4.0A)
0.57A 4u5jA-5w5jA:
24.2
4u5jA-5w5jA:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wnm RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 4


(Mus musculus)
no annotation 8 VAL A  36
ALA A  49
TYR A  98
MET A  99
GLY A 102
ASN A 148
LEU A 150
ASP A 161
VX6  A 402 (-4.6A)
VX6  A 402 (-3.2A)
VX6  A 402 (-4.3A)
None
VX6  A 402 (-3.5A)
None
VX6  A 402 (-4.4A)
VX6  A 402 (-4.3A)
0.47A 4u5jA-5wnmA:
28.9
4u5jA-5wnmA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ao5 SERINE/THREONINE-PRO
TEIN KINASE 3


(Homo sapiens)
no annotation 9 LEU A  33
GLY A  36
VAL A  41
ALA A  54
TYR A 101
GLY A 105
ASN A 151
LEU A 153
ALA A 163
ANP  A 501 ( 3.8A)
None
ANP  A 501 (-4.4A)
ANP  A 501 ( 3.7A)
ANP  A 501 ( 4.2A)
ANP  A 501 ( 4.0A)
ANP  A 501 ( 2.6A)
ANP  A 501 (-4.6A)
None
1.07A 4u5jA-6ao5A:
23.6
4u5jA-6ao5A:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ccf CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE KINASE 1


(Homo sapiens)
no annotation 8 GLY A 137
VAL A 142
ALA A 155
GLY A 236
ASN A 280
LEU A 282
ALA A 292
ASP A 293
None
H1N  A 501 (-4.4A)
H1N  A 501 (-3.4A)
H1N  A 501 (-3.6A)
H1N  A 501 (-4.5A)
H1N  A 501 (-4.8A)
H1N  A 501 ( 3.9A)
H1N  A 501 (-3.5A)
0.51A 4u5jA-6ccfA:
24.8
4u5jA-6ccfA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f3d INTERLEUKIN-1
RECEPTOR-ASSOCIATED
KINASE 4


(Homo sapiens)
no annotation 9 GLY A 195
VAL A 200
ALA A 211
TYR A 264
MET A 265
GLY A 268
ASN A 316
LEU A 318
ASP A 329
None
CJT  A 502 ( 4.8A)
CJT  A 502 (-3.4A)
CJT  A 502 (-4.5A)
CJT  A 502 (-4.9A)
CJT  A 502 ( 4.3A)
None
CJT  A 502 (-4.7A)
CJT  A 502 ( 4.0A)
0.48A 4u5jA-6f3dA:
26.1
4u5jA-6f3dA:
13.57