SIMILAR PATTERNS OF AMINO ACIDS FOR 4TXN_D_URFD302_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aog | TRYPANOTHIONEREDUCTASE (Trypanosomacruzi) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | THR A 194GLY A 196ALA A 285ILE A 200 | NoneMAE A 500 ( 3.9A)NoneFAD A 492 ( 4.3A) | 0.91A | 4txnD-1aogA:undetectable | 4txnD-1aogA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e1c | METHYLMALONYL-COAMUTASE ALPHA CHAIN (Propionibacteriumfreudenreichii) |
PF01642(MM_CoA_mutase)PF02310(B12-binding) | 4 | THR A 360GLY A 358ALA A 355ILE A 290 | None | 0.90A | 4txnD-1e1cA:2.4 | 4txnD-1e1cA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e1c | METHYLMALONYL-COAMUTASE ALPHA CHAIN (Propionibacteriumfreudenreichii) |
PF01642(MM_CoA_mutase)PF02310(B12-binding) | 4 | THR A 706GLY A 708ARG A 471ALA A 338 | NoneB12 A 800 ( 4.4A)NoneNone | 0.96A | 4txnD-1e1cA:2.4 | 4txnD-1e1cA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ey1 | ANTITERMINATIONFACTOR NUSB (Escherichiacoli) |
PF01029(NusB) | 4 | THR A 59GLY A 54ALA A 56ILE A 27 | None | 0.95A | 4txnD-1ey1A:undetectable | 4txnD-1ey1A:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ii0 | ARSENICALPUMP-DRIVING ATPASE (Escherichiacoli) |
PF02374(ArsA_ATPase) | 4 | GLY A 174GLN A 108ALA A 177ILE A 89 | None | 0.90A | 4txnD-1ii0A:undetectable | 4txnD-1ii0A:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iyx | ENOLASE (Enterococcushirae) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | GLY A 106MET A 93ALA A 66ILE A 20 | None | 0.83A | 4txnD-1iyxA:undetectable | 4txnD-1iyxA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jyo | PROTEIN TYROSINEPHOSPHATASE SPTP (Salmonellaenterica) |
PF09119(SicP-binding) | 4 | THR E 51GLY E 54ALA E 38ILE E 72 | None | 0.89A | 4txnD-1jyoE:undetectable | 4txnD-1jyoE:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1keh | PRECURSOR OFCEPHALOSPORINACYLASE (Brevundimonasdiminuta) |
PF01804(Penicil_amidase) | 4 | THR A 218GLY A 216GLN A 189ILE A 326 | None | 0.95A | 4txnD-1kehA:undetectable | 4txnD-1kehA:17.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l3l | TRANSCRIPTIONALACTIVATOR PROTEINTRAR (Agrobacteriumtumefaciens) |
PF00196(GerE)PF03472(Autoind_bind) | 4 | THR A 129GLY A 36ALA A 131ILE A 110 | LAE A1003 (-3.8A)NoneNoneLAE A1003 ( 4.3A) | 0.86A | 4txnD-1l3lA:undetectable | 4txnD-1l3lA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qax | PROTEIN(3-HYDROXY-3-METHYLGLUTARYL-COENZYME AREDUCTASE) (Pseudomonasmevalonii) |
PF00368(HMG-CoA_red) | 4 | GLY A 367GLN A 364ALA A 371ILE A 377 | HMG A1002 (-4.5A)HMG A1002 (-4.2A)HMG A1002 ( 3.8A)HMG A1002 (-4.9A) | 0.92A | 4txnD-1qaxA:undetectable | 4txnD-1qaxA:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rdr | POLIOVIRUS 3DPOLYMERASE (Enterovirus C) |
PF00680(RdRP_1) | 4 | GLY A 207GLN A 84ARG A 306ILE A 305 | None | 0.82A | 4txnD-1rdrA:undetectable | 4txnD-1rdrA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s1f | PUTATIVE CYTOCHROMEP450 (Streptomycescoelicolor) |
PF00067(p450) | 4 | GLY A 219MET A 161ALA A 221ILE A 227 | None | 0.87A | 4txnD-1s1fA:undetectable | 4txnD-1s1fA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w6s | METHANOLDEHYDROGENASESUBUNIT 1 (Methylobacteriumextorquens) |
PF01011(PQQ)PF13360(PQQ_2) | 4 | THR A 491GLY A 477ALA A 516ILE A 533 | None | 0.82A | 4txnD-1w6sA:undetectable | 4txnD-1w6sA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x9y | CYSTEINE PROTEINASE (Staphylococcusaureus) |
PF05543(Peptidase_C47)PF14731(Staphopain_pro) | 4 | GLY A 66GLN A 63ALA A 70ILE A 368 | None | 0.74A | 4txnD-1x9yA:undetectable | 4txnD-1x9yA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xr5 | GENOME POLYPROTEIN (Rhinovirus B) |
PF00680(RdRP_1) | 4 | GLY A 207GLN A 84ARG A 305ILE A 304 | None | 0.91A | 4txnD-1xr5A:undetectable | 4txnD-1xr5A:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zhq | MANNAN-BINDINGLECTIN (Microcystisviridis) |
PF12151(MVL) | 4 | GLY A 89GLN A 30ALA A 85ILE A 109 | EDO A1004 ( 4.6A)NoneNoneNone | 0.94A | 4txnD-1zhqA:undetectable | 4txnD-1zhqA:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zkj | EXTENDED-SPECTRUMBETA-LACTAMASE (Klebsiellaaerogenes) |
PF00144(Beta-lactamase) | 4 | THR A 313GLN A 267ARG A 149ILE A 292 | None | 0.94A | 4txnD-1zkjA:undetectable | 4txnD-1zkjA:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2czq | CUTINASE-LIKEPROTEIN (Cryptococcussp. S-2) |
PF01083(Cutinase) | 4 | GLY A 193GLN A 190ALA A 197ILE A 34 | None | 0.73A | 4txnD-2czqA:3.3 | 4txnD-2czqA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2drq | XYLANASE Y (Bacillushalodurans) |
PF01270(Glyco_hydro_8) | 4 | THR A 326GLY A 330ALA A 268ILE A 291 | None | 0.75A | 4txnD-2drqA:undetectable | 4txnD-2drqA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ibd | POSSIBLETRANSCRIPTIONALREGULATOR (Rhodococcusjostii) |
PF00440(TetR_N) | 4 | GLY A 45ARG A 15ALA A 43ILE A 22 | None | 0.64A | 4txnD-2ibdA:undetectable | 4txnD-2ibdA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jgz | G2/MITOTIC-SPECIFICCYCLIN-B1 (Homo sapiens) |
PF00134(Cyclin_N)PF02984(Cyclin_C) | 4 | GLY B 296GLN B 185ARG B 232ILE B 229 | None | 0.95A | 4txnD-2jgzB:undetectable | 4txnD-2jgzB:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k4v | UNCHARACTERIZEDPROTEIN PA1076 (Pseudomonasaeruginosa) |
PF16703(DUF5064) | 4 | GLY A 80GLN A 21ALA A 76ILE A 25 | None | 0.82A | 4txnD-2k4vA:undetectable | 4txnD-2k4vA:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lbp | LEUCINE-BINDINGPROTEIN (Escherichiacoli) |
PF13458(Peripla_BP_6) | 4 | THR A 220GLY A 217ALA A 213ILE A 186 | None | 0.79A | 4txnD-2lbpA:4.8 | 4txnD-2lbpA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m38 | ANKYRIN REPEAT ANDSTERILE ALPHA MOTIFDOMAIN-CONTAININGPROTEIN 1B (Homo sapiens) |
PF00640(PID) | 4 | THR A 136GLY A 138ALA A 140ILE A 89 | None | 0.85A | 4txnD-2m38A:undetectable | 4txnD-2m38A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2noc | PUTATIVE PERIPLASMICPROTEIN (Salmonellaenterica) |
PF07338(DUF1471) | 4 | GLY A 83MET A 49ALA A 85ILE A 43 | None | 0.93A | 4txnD-2nocA:undetectable | 4txnD-2nocA:15.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oxf | URIDINEPHOSPHORYLASE (Salmonellaenterica) |
PF01048(PNP_UDP_1) | 4 | GLY A1096GLN A1166ARG A1168MET A1197 | None | 0.81A | 4txnD-2oxfA:24.4 | 4txnD-2oxfA:25.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pif | UPF0317 PROTEINPSPTO_5379 (Pseudomonassyringae groupgenomosp. 3) |
PF07286(DUF1445) | 4 | THR A 77GLY A 82ARG A 23ALA A 80 | None | 0.93A | 4txnD-2pifA:undetectable | 4txnD-2pifA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r4j | AEROBICGLYCEROL-3-PHOSPHATEDEHYDROGENASE (Escherichiacoli) |
PF01266(DAO)PF16901(DAO_C) | 4 | THR A 173GLY A 217GLN A 212ILE A 9 | NoneNoneNoneFAD A 600 (-4.6A) | 0.87A | 4txnD-2r4jA:undetectable | 4txnD-2r4jA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wc1 | FLAVODOXIN (Rhodobactercapsulatus) |
PF00258(Flavodoxin_1) | 4 | GLY A 133GLN A 157ARG A 164ALA A 131 | None | 0.95A | 4txnD-2wc1A:2.7 | 4txnD-2wc1A:25.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xij | METHYLMALONYL-COAMUTASE,MITOCHONDRIAL (Homo sapiens) |
PF01642(MM_CoA_mutase)PF02310(B12-binding) | 4 | THR A 382GLY A 380ALA A 377ILE A 311 | None | 0.87A | 4txnD-2xijA:2.9 | 4txnD-2xijA:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bje | NUCLEOSIDEPHOSPHORYLASE,PUTATIVE (Trypanosomabrucei) |
PF01048(PNP_UDP_1) | 5 | THR A 140GLY A 142GLN A 246ARG A 248MET A 285 | R1P A 401 (-3.0A)URA A 501 (-3.4A)URA A 501 (-3.0A)URA A 501 (-2.9A)R1P A 401 ( 3.9A) | 0.20A | 4txnD-3bjeA:22.9 | 4txnD-3bjeA:25.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cp2 | TRNA URIDINE5-CARBOXYMETHYLAMINOMETHYL MODIFICATIONENZYME GIDA (Escherichiacoli) |
PF01134(GIDA)PF13932(GIDA_assoc) | 4 | THR A 95GLY A 52ALA A 97ILE A 74 | None | 0.82A | 4txnD-3cp2A:undetectable | 4txnD-3cp2A:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3das | PUTATIVEOXIDOREDUCTASE (Streptomycescoelicolor) |
PF07995(GSDH) | 4 | THR A 157GLY A 143ALA A 155ILE A 109 | None | 0.96A | 4txnD-3dasA:undetectable | 4txnD-3dasA:22.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e7f | 6-PHOSPHOGLUCONOLACTONASE (Trypanosomabrucei) |
PF01182(Glucosamine_iso) | 4 | THR A 166GLY A 164ALA A 241ILE A 230 | None | 0.81A | 4txnD-3e7fA:undetectable | 4txnD-3e7fA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eef | N-CARBAMOYLSARCOSINEAMIDASE RELATEDPROTEIN (Thermoplasmaacidophilum) |
PF00857(Isochorismatase) | 4 | THR A 27GLY A 29ALA A 31ILE A 79 | None | 0.73A | 4txnD-3eefA:undetectable | 4txnD-3eefA:20.92 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3euf | URIDINEPHOSPHORYLASE 1 (Homo sapiens) |
PF01048(PNP_UDP_1) | 5 | THR A 141GLY A 143GLN A 217ARG A 219MET A 249 | PO4 A 401 ( 3.0A)BAU A 400 (-3.3A)BAU A 400 (-3.1A)BAU A 400 (-3.0A)BAU A 400 (-3.8A) | 0.25A | 4txnD-3eufA:41.6 | 4txnD-3eufA:40.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g05 | TRNA URIDINE5-CARBOXYMETHYLAMINOMETHYL MODIFICATIONENZYME MNMG (Escherichiacoli) |
PF01134(GIDA)PF13932(GIDA_assoc) | 4 | THR A 95GLY A 52ALA A 97ILE A 74 | None | 0.81A | 4txnD-3g05A:undetectable | 4txnD-3g05A:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ggd | SAM-DEPENDENTMETHYLTRANSFERASE (Trichormusvariabilis) |
PF13649(Methyltransf_25) | 4 | GLY A 218ARG A 48ALA A 236ILE A 161 | EDO A 261 (-3.9A)EDO A 261 ( 3.8A)NoneEDO A 255 (-4.5A) | 0.93A | 4txnD-3ggdA:undetectable | 4txnD-3ggdA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h8l | NADH OXIDASE (Acidianusambivalens) |
PF07992(Pyr_redox_2) | 4 | THR A 262GLY A 152ALA A 150ILE A 257 | None | 0.95A | 4txnD-3h8lA:undetectable | 4txnD-3h8lA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hbc | CHOLOYLGLYCINEHYDROLASE (Bacteroidesthetaiotaomicron) |
PF02275(CBAH) | 4 | THR A 27GLY A 41ALA A 29ILE A 239 | None | 0.83A | 4txnD-3hbcA:undetectable | 4txnD-3hbcA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjl | FLAGELLAR MOTORSWITCH PROTEIN FLIG (Aquifexaeolicus) |
PF01706(FliG_C)PF14841(FliG_M)PF14842(FliG_N) | 4 | GLY A 198ARG A 231ALA A 202ILE A 232 | None | 0.90A | 4txnD-3hjlA:undetectable | 4txnD-3hjlA:24.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i1c | DIISOPROPYL-FLUOROPHOSPHATASE (Loligo vulgaris) |
PF08450(SGL) | 4 | THR A 279GLY A 301GLN A 304ILE A 282 | None | 0.92A | 4txnD-3i1cA:undetectable | 4txnD-3i1cA:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k2d | ABC-TYPE METAL IONTRANSPORT SYSTEM,PERIPLASMICCOMPONENT (Vibriovulnificus) |
PF03180(Lipoprotein_9) | 4 | THR A 71GLN A 87ALA A 75ILE A 81 | None | 0.87A | 4txnD-3k2dA:undetectable | 4txnD-3k2dA:24.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kvd | LIPOPROTEIN (Neisseriameningitidis) |
PF08794(Lipoprot_C) | 4 | THR D 204GLY D 290ALA D 271ILE D 263 | None | 0.85A | 4txnD-3kvdD:undetectable | 4txnD-3kvdD:24.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kvy | URIDINEPHOSPHORYLASE (Bos taurus) |
PF01048(PNP_UDP_1) | 6 | THR A 140GLY A 142GLN A 216ARG A 218MET A 248ILE A 280 | SO4 A 311 ( 3.1A)URA A 312 (-3.3A)URA A 312 (-3.3A)URA A 312 (-2.9A)URA A 312 ( 3.7A)None | 0.36A | 4txnD-3kvyA:41.7 | 4txnD-3kvyA:41.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kws | PUTATIVE SUGARISOMERASE (Parabacteroidesdistasonis) |
PF01261(AP_endonuc_2) | 4 | THR A 185GLY A 142ALA A 138ILE A 108 | None | 0.94A | 4txnD-3kwsA:undetectable | 4txnD-3kwsA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l01 | GLGA GLYCOGENSYNTHASE (Pyrococcusabyssi) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 4 | THR A 102GLY A 104ALA A 106ILE A 78 | None | 0.81A | 4txnD-3l01A:2.1 | 4txnD-3l01A:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mlp | TRANSCRIPTION FACTORCOE1 (Mus musculus) |
PF01833(TIG)PF16422(COE1_DBD)PF16423(COE1_HLH) | 4 | GLY A 46GLN A 78ALA A 42ILE A 120 | None | 0.74A | 4txnD-3mlpA:undetectable | 4txnD-3mlpA:23.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n0l | SERINEHYDROXYMETHYLTRANSFERASE (Campylobacterjejuni) |
PF00464(SHMT) | 4 | GLY A 331MET A 27ALA A 329ILE A 382 | None | 0.94A | 4txnD-3n0lA:undetectable | 4txnD-3n0lA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n2c | PROLIDASE (unidentified) |
PF01979(Amidohydro_1) | 5 | GLY A 131GLN A 186MET A 227ALA A 109ILE A 127 | NoneNoneKCX A 188 ( 4.5A)NoneNone | 1.45A | 4txnD-3n2cA:undetectable | 4txnD-3n2cA:24.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nyi | FAT ACID-BINDINGPROTEIN (Eubacteriumventriosum) |
PF02645(DegV) | 4 | THR A 182GLY A 186ALA A 184ILE A 206 | None | 0.95A | 4txnD-3nyiA:undetectable | 4txnD-3nyiA:24.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3otr | ENOLASE (Toxoplasmagondii) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | GLY A 112MET A 93ALA A 66ILE A 21 | None | 0.86A | 4txnD-3otrA:undetectable | 4txnD-3otrA:22.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p0f | URIDINEPHOSPHORYLASE 2 (Homo sapiens) |
PF01048(PNP_UDP_1) | 5 | THR A 147GLY A 149GLN A 223ARG A 225MET A 255 | BAU A 400 (-4.5A)BAU A 400 (-3.5A)BAU A 400 (-3.1A)BAU A 400 (-2.8A)BAU A 400 (-3.9A) | 0.31A | 4txnD-3p0fA:39.5 | 4txnD-3p0fA:42.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q3u | LIGNIN PEROXIDASE (Trametopsiscervina) |
PF00141(peroxidase)PF11895(Peroxidase_ext) | 4 | GLY A 123GLN A 256ALA A 117ILE A 177 | None | 0.94A | 4txnD-3q3uA:undetectable | 4txnD-3q3uA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qp9 | TYPE I POLYKETIDESYNTHASE PIKAII (Streptomycesvenezuelae) |
PF08659(KR) | 5 | GLY A 156GLN A 199ARG A 210ALA A 384ILE A 385 | None | 1.49A | 4txnD-3qp9A:2.7 | 4txnD-3qp9A:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qtp | ENOLASE 1 (Entamoebahistolytica) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | GLY A 105MET A 92ALA A 65ILE A 20 | None | 0.73A | 4txnD-3qtpA:undetectable | 4txnD-3qtpA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ucq | AMYLOSUCRASE (Deinococcusgeothermalis) |
PF00128(Alpha-amylase) | 4 | THR A 387GLY A 490ARG A 557ALA A 565 | None | 0.92A | 4txnD-3ucqA:undetectable | 4txnD-3ucqA:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ujq | LEGUME LECTIN (Lablabpurpureus) |
PF00139(Lectin_legB) | 4 | THR A 235GLY A 109ALA A 233ILE A 54 | None | 0.91A | 4txnD-3ujqA:undetectable | 4txnD-3ujqA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vbe | BETA-CYANOALNINESYNTHASE (Glycine max) |
PF00291(PALP) | 4 | THR A 74GLY A 78ALA A 330ILE A 340 | None | 0.96A | 4txnD-3vbeA:undetectable | 4txnD-3vbeA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9i | MULTIDRUG RESISTANCEPROTEIN MEXB (Pseudomonasaeruginosa) |
PF00873(ACR_tran) | 4 | THR A 343GLY A 345ALA A 347ILE A 402 | None | 0.93A | 4txnD-3w9iA:undetectable | 4txnD-3w9iA:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wia | NITRITE REDUCTASE (Geobacilluskaustophilus) |
PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | THR A 64GLY A 147ALA A 62ILE A 52 | None | 0.94A | 4txnD-3wiaA:undetectable | 4txnD-3wiaA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wrt | BETA-LACTAMASE (Chromohalobactersp. 560) |
PF00144(Beta-lactamase) | 4 | THR A 317GLN A 268ARG A 149ILE A 293 | None | 0.93A | 4txnD-3wrtA:undetectable | 4txnD-3wrtA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c30 | DNA HELICASE II (Deinococcusradiodurans) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 4 | THR A 39GLY A 35GLN A 258ARG A 617 | MG A1663 ( 2.8A)ANP A1662 (-3.1A)ANP A1662 (-3.2A)ANP A1662 (-3.0A) | 0.88A | 4txnD-4c30A:undetectable | 4txnD-4c30A:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d65 | PORIN 2 (Providenciastuartii) |
PF00267(Porin_1) | 4 | THR A 239GLN A 152ALA A 215ILE A 98 | None | 0.93A | 4txnD-4d65A:undetectable | 4txnD-4d65A:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dal | PUTATIVE ALDEHYDEDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00171(Aldedh) | 4 | THR A 206GLY A 208ALA A 210ILE A 41 | None | 0.87A | 4txnD-4dalA:undetectable | 4txnD-4dalA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fxs | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Vibrio cholerae) |
PF00478(IMPDH)PF00571(CBS) | 4 | THR A 53GLY A 363ALA A 367ILE A 423 | NoneIMP A 701 (-3.7A)NoneNone | 0.89A | 4txnD-4fxsA:undetectable | 4txnD-4fxsA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gpg | PROTEASE 1 (Achromobacterlyticus) |
PF00089(Trypsin) | 4 | THR A 85GLY A 89ARG A 156ALA A 87 | None | 0.78A | 4txnD-4gpgA:undetectable | 4txnD-4gpgA:24.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4irt | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF15892(BNR_4) | 4 | GLY A 407MET A 328ALA A 413ILE A 415 | None | 0.82A | 4txnD-4irtA:undetectable | 4txnD-4irtA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jz5 | GP26 (Listeria phageP40) |
PF01183(Glyco_hydro_25) | 4 | GLY A 18MET A 53ALA A 181ILE A 179 | None | 0.93A | 4txnD-4jz5A:undetectable | 4txnD-4jz5A:24.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nwz | FAD-DEPENDENTPYRIDINENUCLEOTIDE-DISULFIDEOXIDOREDUCTASE (Caldalkalibacillusthermarum) |
PF07992(Pyr_redox_2) | 4 | GLY A 54MET A 178ALA A 52ILE A 135 | None | 0.85A | 4txnD-4nwzA:undetectable | 4txnD-4nwzA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o7p | MALTOKINASE (Mycobacteriumtuberculosis) |
no annotation | 4 | THR A 212GLY A 189ARG A 174ILE A 170 | None | 0.93A | 4txnD-4o7pA:undetectable | 4txnD-4o7pA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ofx | CYSTATHIONINEBETA-SYNTHASE (Coxiellaburnetii) |
PF00291(PALP) | 4 | GLY A 77GLN A 146ALA A 81ILE A 51 | None | 0.89A | 4txnD-4ofxA:undetectable | 4txnD-4ofxA:25.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4plh | MALATE DEHYDROGENASE (Apicomplexa) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | GLY A 273MET A 172ALA A 259ILE A 286 | None | 0.85A | 4txnD-4plhA:2.5 | 4txnD-4plhA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qav | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2 (Neisseriameningitidis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | GLY A 200MET A 207ALA A 195ILE A 110 | None | 0.96A | 4txnD-4qavA:undetectable | 4txnD-4qavA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qg5 | PUTATIVEPHOSPHOGLUCOMUTASE (Leishmaniamajor) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 4 | THR A 402GLY A 412ALA A 415ILE A 307 | None | 0.87A | 4txnD-4qg5A:undetectable | 4txnD-4qg5A:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qts | CRISPR TYPEIII-ASSOCIATED RAMPPROTEIN CSM4 (Methanocaldococcusjannaschii) |
PF03787(RAMPs) | 4 | THR A 317GLY A 276MET A 273ILE A 27 | None | 0.81A | 4txnD-4qtsA:undetectable | 4txnD-4qtsA:24.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r2w | URIDINEPHOSPHORYLASE (Shewanellaoneidensis) |
PF01048(PNP_UDP_1) | 5 | THR A 91GLY A 93GLN A 163ARG A 165MET A 194 | SO4 A 302 ( 3.0A)NoneNoneNoneGOL A 303 (-3.5A) | 0.31A | 4txnD-4r2wA:24.8 | 4txnD-4r2wA:24.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r31 | URIDINEPHOSPHORYLASE (Actinobacillussuccinogenes) |
PF01048(PNP_UDP_1) | 4 | GLY A 94GLN A 164ARG A 166MET A 195 | NoneNoneNoneGOL A 301 (-4.0A) | 0.66A | 4txnD-4r31A:24.2 | 4txnD-4r31A:24.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ru4 | TAIL SPIKE PROTEINGP49 (Pseudomonasvirus LKA1) |
PF13229(Beta_helix) | 4 | THR A 464GLY A 500ALA A 502ILE A 523 | None | 0.79A | 4txnD-4ru4A:undetectable | 4txnD-4ru4A:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s1w | GLUTAMINE--FRUCTOSE-6-PHOSPHATEAMINOTRANSFERASE[ISOMERIZING] (Staphylococcusaureus) |
PF01380(SIS) | 4 | THR A 404GLN A 347ALA A 408ILE A 267 | None | 0.84A | 4txnD-4s1wA:3.4 | 4txnD-4s1wA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3j | CORTICAL-LYTICENZYME (Bacillus cereus) |
PF00704(Glyco_hydro_18)PF01476(LysM) | 4 | GLN A 365ARG A 64ALA A 386ILE A 4 | None | 0.94A | 4txnD-4s3jA:undetectable | 4txnD-4s3jA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgj | UNCHARACTERIZEDPROTEIN (Pectobacteriumatrosepticum) |
PF07005(DUF1537)PF17042(DUF1357_C) | 4 | THR A 418GLY A 375ALA A 379ILE A 380 | None | 0.96A | 4txnD-4xgjA:2.5 | 4txnD-4xgjA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xij | SHIKIMATE5-DEHYDROGENASE (Mycolicibacteriumfortuitum) |
PF08501(Shikimate_dh_N) | 4 | GLY A 115ARG A 210ALA A 113ILE A 235 | None | 0.65A | 4txnD-4xijA:undetectable | 4txnD-4xijA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwt | DR2417 (Deinococcusradiodurans) |
PF00753(Lactamase_B)PF07521(RMMBL) | 4 | THR A 394GLY A 202ALA A 198ILE A 162 | None | 0.58A | 4txnD-4xwtA:undetectable | 4txnD-4xwtA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwx | SHC-TRANSFORMINGPROTEIN 1 (Homo sapiens) |
PF00640(PID) | 4 | GLY A 155GLN A 188ALA A 153ILE A 194 | None | 0.93A | 4txnD-4xwxA:undetectable | 4txnD-4xwxA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y0a | SHIKIMATE KINASE (Acinetobacterbaumannii) |
PF01202(SKI) | 4 | THR A 94GLY A 96ALA A 98ILE A 99 | NoneSKM A 201 (-3.1A)NoneNone | 0.89A | 4txnD-4y0aA:undetectable | 4txnD-4y0aA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yg8 | CHITIN BIOSYNTHESISPROTEIN CHS5 (Saccharomycescerevisiae) |
PF00533(BRCT)PF16893(fn3_2) | 4 | GLY A 173GLN A 91ALA A 201ILE A 199 | None | 0.83A | 4txnD-4yg8A:undetectable | 4txnD-4yg8A:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a24 | DIONAIN-1 (Dionaeamuscipula) |
PF00112(Peptidase_C1) | 4 | GLY A 171MET A 201ALA A 131ILE A 136 | None | 0.95A | 4txnD-5a24A:undetectable | 4txnD-5a24A:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b13 | PHYCOERYTHRIN ALPHASUBUNIT (Palmariapalmata) |
PF00502(Phycobilisome) | 4 | GLY A 150GLN A 147ARG A 33ALA A 154 | None | 0.84A | 4txnD-5b13A:undetectable | 4txnD-5b13A:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bu6 | BPSB (PGAB),POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINEN-DEACETYLASE (Bordetellabronchiseptica) |
PF01522(Polysacc_deac_1) | 4 | THR A 259GLN A 287ALA A 263ILE A 248 | None | 0.96A | 4txnD-5bu6A:undetectable | 4txnD-5bu6A:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fmg | PROTEASOME SUBUNITBETA TYPE (Plasmodiumfalciparum) |
PF00227(Proteasome) | 4 | THR M 55GLY M 38ALA M 53ILE M 71 | None | 0.96A | 4txnD-5fmgM:undetectable | 4txnD-5fmgM:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hd2 | PARASPORAL CRYSTALPROTEIN (Bacillusthuringiensis) |
PF03318(ETX_MTX2) | 4 | GLY A 179GLN A 60ALA A 256ILE A 134 | None | 0.72A | 4txnD-5hd2A:undetectable | 4txnD-5hd2A:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lhv | URIDINEPHOSPHORYLASE (Vibrio cholerae) |
PF01048(PNP_UDP_1) | 5 | THR A 93GLN A 165ARG A 167MET A 196ILE A 220 | SO4 A 301 ( 2.9A)URA A 304 ( 2.9A)URA A 304 ( 2.9A)URI A 303 ( 3.7A)URA A 304 (-4.3A) | 1.38A | 4txnD-5lhvA:24.9 | 4txnD-5lhvA:25.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lhv | URIDINEPHOSPHORYLASE (Vibrio cholerae) |
PF01048(PNP_UDP_1) | 5 | THR A 93GLY A 95GLN A 165ARG A 167MET A 196 | SO4 A 301 ( 2.9A)URI A 303 ( 3.4A)URA A 304 ( 2.9A)URA A 304 ( 2.9A)URI A 303 ( 3.7A) | 0.38A | 4txnD-5lhvA:24.9 | 4txnD-5lhvA:25.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ojy | TETR FAMILYTRANSCRIPTIONREGULATOR (Streptomycesalboniger) |
no annotation | 4 | THR A 167GLY A 169ALA A 171ILE A 122 | NoneNoneNoneGOL A 302 ( 4.7A) | 0.96A | 4txnD-5ojyA:undetectable | 4txnD-5ojyA:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uze | INOSINE-5'-MONOPHOSPHATEDEHYDROGENASE,INOSINE-5'-MONOPHOSPHATEDEHYDROGENASE (Clostridiumperfringens) |
PF00478(IMPDH) | 4 | THR A 51GLY A 359ALA A 363ILE A 417 | NoneIMP A 500 (-3.5A)NoneNone | 0.89A | 4txnD-5uzeA:undetectable | 4txnD-5uzeA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vc2 | SERINEHYDROXYMETHYLTRANSFERASE (Helicobacterpylori) |
PF00464(SHMT) | 4 | GLY A 333MET A 29ALA A 331ILE A 384 | None | 0.83A | 4txnD-5vc2A:undetectable | 4txnD-5vc2A:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xio | PROLINE-TRNASYNTHETASE CLASS IIAARS (YBAK RNABINDING DOMAIN PLUSTRNA SYNTHETASE) (Cryptosporidiumparvum) |
no annotation | 4 | GLY A 437GLN A 624ALA A 448ILE A 435 | None | 0.95A | 4txnD-5xioA:undetectable | 4txnD-5xioA:12.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bk7 | ELONGATION FACTOR G (Enterococcusfaecalis) |
no annotation | 4 | THR A 325GLY A 378ALA A 376ILE A 351 | None | 0.93A | 4txnD-6bk7A:2.8 | 4txnD-6bk7A:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6emk | SERINE/THREONINE-PROTEIN KINASE TOR2 (Saccharomycescerevisiae) |
no annotation | 4 | GLY A1385GLN A1391ALA A1383ILE A1371 | None | 0.83A | 4txnD-6emkA:undetectable | 4txnD-6emkA:13.40 |