SIMILAR PATTERNS OF AMINO ACIDS FOR 4TVT_A_ASCA303_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ai1 | IGG1-KAPPA 59.1 FAB(HEAVY CHAIN) (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | LEU H 143SER H 188LYS H 145VAL H 177 | None | 1.16A | 4tvtA-1ai1H:1.3 | 4tvtA-1ai1H:22.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1aun | PR-5D (Nicotianatabacum) |
PF00314(Thaumatin) | 4 | LEU A 83GLU A 85SER A 100ILE A 102 | None | 0.17A | 4tvtA-1aunA:33.6 | 4tvtA-1aunA:52.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bvu | PROTEIN (GLUTAMATEDEHYDROGENASE) (Thermococcuslitoralis) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | LEU A 316SER A 294ILE A 216VAL A 241 | None | 1.02A | 4tvtA-1bvuA:0.0 | 4tvtA-1bvuA:20.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1du5 | ZEAMATIN (Zea mays) |
PF00314(Thaumatin) | 4 | LEU A 82GLU A 84SER A 99ILE A 101 | None | 0.24A | 4tvtA-1du5A:32.9 | 4tvtA-1du5A:54.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hh2 | N UTILIZATIONSUBSTANCE PROTEIN A (Thermotogamaritima) |
PF00575(S1)PF08529(NusA_N)PF13184(KH_5) | 4 | LEU P 6GLU P 7ILE P 56VAL P 47 | None | 1.22A | 4tvtA-1hh2P:undetectable | 4tvtA-1hh2P:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ivh | ISOVALERYL-COADEHYDROGENASE (Homo sapiens) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | LYS A 164ILE A 193LYS A 181VAL A 244 | NoneNoneNoneCOS A 400 (-4.4A) | 1.13A | 4tvtA-1ivhA:0.0 | 4tvtA-1ivhA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jk0 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESMALL CHAIN 2 (Saccharomycescerevisiae) |
PF00268(Ribonuc_red_sm) | 4 | LYS B 185GLU B 186ILE B 101LYS B 100 | None | 1.07A | 4tvtA-1jk0B:undetectable | 4tvtA-1jk0B:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l5p | FERREDOXIN (Trichomonasvaginalis) |
PF00111(Fer2) | 4 | LEU A 76GLU A 63ILE A 80VAL A 56 | FES A 94 ( 4.4A)NoneNoneNone | 1.21A | 4tvtA-1l5pA:0.9 | 4tvtA-1l5pA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1obf | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Achromobacterxylosoxidans) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | LEU O 300SER O 311ILE O 243VAL O 180 | None | 1.15A | 4tvtA-1obfO:0.0 | 4tvtA-1obfO:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ow5 | SERINE/THREONINE-PROTEIN KINASE STE11 (Saccharomycescerevisiae) |
PF07647(SAM_2) | 4 | LEU A 75SER A 78ILE A 52VAL A 25 | None | 0.81A | 4tvtA-1ow5A:undetectable | 4tvtA-1ow5A:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pwe | L-SERINE DEHYDRATASE (Rattusnorvegicus) |
PF00291(PALP) | 4 | LEU A 29GLU A 262SER A 16VAL A 22 | None | 1.17A | 4tvtA-1pweA:0.0 | 4tvtA-1pweA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qaf | PROTEIN (COPPERAMINE OXIDASE) (Escherichiacoli) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3)PF07833(Cu_amine_oxidN1) | 4 | GLU A 203SER A 202ILE A 275LYS A 274 | None | 1.08A | 4tvtA-1qafA:undetectable | 4tvtA-1qafA:14.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s1d | APYRASE (Homo sapiens) |
PF06079(Apyrase) | 4 | LEU A 100GLU A 329ILE A 328VAL A 289 | NoneTRS A5001 (-3.0A)NoneNone | 1.18A | 4tvtA-1s1dA:undetectable | 4tvtA-1s1dA:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1spp | MAJOR SEMINAL PLASMAGLYCOPROTEIN PSP-I (Sus scrofa) |
PF00431(CUB) | 4 | LYS A 91LEU A 61GLU A 59SER A 69 | None | 1.20A | 4tvtA-1sppA:undetectable | 4tvtA-1sppA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vhz | ADP COMPOUNDSHYDROLASE NUDE (Escherichiacoli) |
PF00293(NUDIX) | 4 | GLU A 99SER A 78ILE A 52VAL A 50 | None | 1.21A | 4tvtA-1vhzA:undetectable | 4tvtA-1vhzA:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vrd | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Thermotogamaritima) |
PF00478(IMPDH)PF00571(CBS) | 4 | LEU A 257ILE A 260LYS A 261VAL A 230 | None | 1.22A | 4tvtA-1vrdA:undetectable | 4tvtA-1vrdA:17.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vtl | TATA BINDING PROTEIN(TBP) (Arabidopsisthaliana) |
PF00352(TBP) | 4 | GLU E 186SER E 19ILE E 21VAL E 124 | None | 1.20A | 4tvtA-1vtlE:undetectable | 4tvtA-1vtlE:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xjv | PROTECTION OFTELOMERES 1 (Homo sapiens) |
PF02765(POT1)PF16686(POT1PC) | 4 | LEU A 261SER A 193ILE A 218VAL A 183 | None | 1.13A | 4tvtA-1xjvA:undetectable | 4tvtA-1xjvA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ypz | H2-T22 PROTEIN (Mus musculus) |
PF00129(MHC_I)PF07654(C1-set) | 4 | GLU A 40SER A 37ILE A 23VAL A 25 | None | 1.13A | 4tvtA-1ypzA:undetectable | 4tvtA-1ypzA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yve | ACETOHYDROXY ACIDISOMEROREDUCTASE (Spinaciaoleracea) |
PF01450(IlvC)PF07991(IlvN) | 4 | LEU I 501GLU I 496SER I 500VAL I 258 | HIO I 603 (-4.6A)HIO I 603 (-2.8A)NoneNone | 1.15A | 4tvtA-1yveI:undetectable | 4tvtA-1yveI:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z6r | MLC PROTEIN (Escherichiacoli) |
PF00480(ROK) | 4 | LEU A 344SER A 345ILE A 340VAL A 373 | None | 1.22A | 4tvtA-1z6rA:undetectable | 4tvtA-1z6rA:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bru | NAD(P)TRANSHYDROGENASESUBUNIT BETA (Escherichiacoli) |
PF02233(PNTB) | 4 | LEU C 26ILE C 182LYS C 20VAL C 179 | None | 1.15A | 4tvtA-2bruC:undetectable | 4tvtA-2bruC:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ebu | REPLICATION FACTOR CSUBUNIT 1 (Homo sapiens) |
PF00533(BRCT) | 4 | LEU A 418GLU A 472SER A 420ILE A 421 | None | 1.20A | 4tvtA-2ebuA:undetectable | 4tvtA-2ebuA:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ejv | L-THREONINE3-DEHYDROGENASE (Thermusthermophilus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLU A 148SER A 89ILE A 112VAL A 115 | ZN A 501 ( 4.0A)NoneNoneNone | 1.09A | 4tvtA-2ejvA:undetectable | 4tvtA-2ejvA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eyq | TRANSCRIPTION-REPAIRCOUPLING FACTOR (Escherichiacoli) |
PF00270(DEAD)PF00271(Helicase_C)PF02559(CarD_CdnL_TRCF)PF03461(TRCF) | 4 | LEU A1060SER A1010ILE A1063VAL A1004 | None | 1.16A | 4tvtA-2eyqA:undetectable | 4tvtA-2eyqA:10.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hi9 | PLASMA SERINEPROTEASE INHIBITOR (Homo sapiens) |
PF00079(Serpin) | 4 | LYS A 187GLU A 335SER A 288LYS A 286 | None | 1.22A | 4tvtA-2hi9A:undetectable | 4tvtA-2hi9A:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iod | DIHYDROFLAVONOL4-REDUCTASE (Vitis vinifera) |
PF01370(Epimerase) | 4 | GLU A 171SER A 127ILE A 189VAL A 132 | None | 1.22A | 4tvtA-2iodA:undetectable | 4tvtA-2iodA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ip2 | PROBABLEPHENAZINE-SPECIFICMETHYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00891(Methyltransf_2)PF16864(Dimerisation2) | 4 | LEU A 254SER A 251ILE A 243VAL A 305 | None | 1.23A | 4tvtA-2ip2A:undetectable | 4tvtA-2ip2A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2izw | RYEGRASS MOTTLEVIRUS COAT PROTEIN (Ryegrass mottlevirus) |
PF00729(Viral_coat) | 4 | LEU A 209SER A 207ILE A 162VAL A 132 | None | 1.11A | 4tvtA-2izwA:undetectable | 4tvtA-2izwA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o9r | BETA-GLUCOSIDASE B (Paenibacilluspolymyxa) |
PF00232(Glyco_hydro_1) | 4 | GLU A 225SER A 301ILE A 303VAL A 314 | None | 1.16A | 4tvtA-2o9rA:undetectable | 4tvtA-2o9rA:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pmz | DNA-DIRECTED RNAPOLYMERASE SUBUNITA' (Sulfolobussolfataricus) |
PF04998(RNA_pol_Rpb1_5) | 4 | LEU C 54GLU C 58ILE C 51VAL C 17 | None | 1.08A | 4tvtA-2pmzC:undetectable | 4tvtA-2pmzC:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rg4 | UNCHARACTERIZEDPROTEIN (Oceanicolagranulosus) |
PF13759(2OG-FeII_Oxy_5) | 4 | LEU A 63SER A 59ILE A 107VAL A 201 | None | 1.17A | 4tvtA-2rg4A:undetectable | 4tvtA-2rg4A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rre | PUTATIVEUNCHARACTERIZEDPROTEIN (Mus musculus) |
PF16725(Nucleolin_bd) | 4 | LEU A 72ILE A 66LYS A 70VAL A 62 | None | 1.05A | 4tvtA-2rreA:undetectable | 4tvtA-2rreA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vbf | BRANCHED-CHAINALPHA-KETOACIDDECARBOXYLASE (Lactococcuslactis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | LEU A 250SER A 252ILE A 236VAL A 210 | LEU A 250 ( 0.6A)SER A 252 ( 0.0A)ILE A 236 ( 0.6A)VAL A 210 ( 0.6A) | 1.15A | 4tvtA-2vbfA:undetectable | 4tvtA-2vbfA:15.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2woo | ATPASE GET3 (Schizosaccharomycespombe) |
PF02374(ArsA_ATPase) | 4 | LEU A 91GLU A 95SER A 92ILE A 87 | None | 1.11A | 4tvtA-2wooA:undetectable | 4tvtA-2wooA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xh1 | KYNURENINE/ALPHA-AMINOADIPATEAMINOTRANSFERASE,MITOCHONDRIAL (Homo sapiens) |
PF00155(Aminotran_1_2) | 4 | LEU A 425SER A 424ILE A 363VAL A 366 | None | 0.88A | 4tvtA-2xh1A:undetectable | 4tvtA-2xh1A:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zwk | INTIMIN (Escherichiacoli) |
PF02368(Big_2)PF07979(Intimin_C) | 4 | GLU A 155SER A 161ILE A 149LYS A 150 | None | 1.03A | 4tvtA-2zwkA:undetectable | 4tvtA-2zwkA:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bvc | UNCHARACTERIZEDPROTEIN ISM_01780 (Roseovariusnubinhibens) |
PF13759(2OG-FeII_Oxy_5) | 4 | LEU A 63SER A 59ILE A 107VAL A 201 | None | 1.00A | 4tvtA-3bvcA:undetectable | 4tvtA-3bvcA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c6c | 3-KETO-5-AMINOHEXANOATE CLEAVAGE ENZYME (Cupriaviduspinatubonensis) |
PF05853(BKACE) | 4 | GLU A 165ILE A 124LYS A 163VAL A 80 | None | 1.16A | 4tvtA-3c6cA:undetectable | 4tvtA-3c6cA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c8c | METHYL-ACCEPTINGCHEMOTAXIS PROTEIN (Vibrio cholerae) |
PF02743(dCache_1) | 4 | GLU A 227ILE A 253LYS A 252VAL A 255 | None | 1.20A | 4tvtA-3c8cA:undetectable | 4tvtA-3c8cA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dmk | DOWN SYNDROME CELLADHESION MOLECULE(DSCAM) ISOFORM1.30.30, N-TERMINALEIGHT IG DOMAINS (Drosophilamelanogaster) |
PF07679(I-set)PF13927(Ig_3) | 4 | SER A 730ILE A 733LYS A 728VAL A 742 | None | 1.17A | 4tvtA-3dmkA:undetectable | 4tvtA-3dmkA:14.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gdn | R-OXYNITRILE LYASEISOENZYME 1 (Prunus dulcis) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | LEU A 266SER A 269ILE A 220VAL A 233 | None | 1.03A | 4tvtA-3gdnA:undetectable | 4tvtA-3gdnA:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i4s | HISTIDINE TRIADPROTEIN (Bradyrhizobiumjaponicum) |
PF01230(HIT) | 4 | LEU A 55GLU A 97SER A 58VAL A 128 | None | 1.21A | 4tvtA-3i4sA:undetectable | 4tvtA-3i4sA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l9k | RE64145P (Drosophilamelanogaster) |
PF03259(Robl_LC7) | 4 | LEU A 35SER A 33ILE A 22VAL A 24 | None | 1.14A | 4tvtA-3l9kA:undetectable | 4tvtA-3l9kA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ohe | HISTIDINE TRIAD(HIT) PROTEIN (Marinobacterhydrocarbonoclasticus) |
PF01230(HIT) | 4 | LEU A 135GLU A 60SER A 18VAL A 37 | None | 1.05A | 4tvtA-3oheA:undetectable | 4tvtA-3oheA:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pao | ADENOSINE DEAMINASE (Pseudomonasaeruginosa) |
PF00962(A_deaminase) | 4 | LEU A 312SER A 311LYS A 12VAL A 274 | None | 1.14A | 4tvtA-3paoA:undetectable | 4tvtA-3paoA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r75 | ANTHRANILATE/PARA-AMINOBENZOATESYNTHASES COMPONENTI (Burkholderialata) |
PF00117(GATase)PF00425(Chorismate_bind) | 4 | LEU A 204SER A 347ILE A 331VAL A 72 | None | 1.21A | 4tvtA-3r75A:undetectable | 4tvtA-3r75A:15.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3red | HYDROXYNITRILE LYASE (Prunus mume) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | LEU A 267SER A 270ILE A 220VAL A 234 | None | 1.04A | 4tvtA-3redA:undetectable | 4tvtA-3redA:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3szb | ALDEHYDEDEHYDROGENASE (Homo sapiens) |
PF00171(Aldedh) | 4 | GLU A 269SER A 266LYS A 262VAL A 226 | None | 0.99A | 4tvtA-3szbA:undetectable | 4tvtA-3szbA:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t7f | UBIQUITIN-LIKEMODIFIER-ACTIVATINGENZYME ATG7 (Saccharomycescerevisiae) |
PF16420(ATG7_N) | 4 | LYS A 237LEU A 161GLU A 158SER A 160 | None | 1.00A | 4tvtA-3t7fA:undetectable | 4tvtA-3t7fA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vs8 | TYPE III POLYKETIDESYNTHASE (Azotobactervinelandii) |
PF02797(Chal_sti_synt_C) | 4 | LYS A 75LEU A 363GLU A 364SER A 360 | None | 1.09A | 4tvtA-3vs8A:undetectable | 4tvtA-3vs8A:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4btg | MAJOR INNER PROTEINP1 (Pseudomonasvirus phi6) |
no annotation | 4 | LEU A 526GLU A 525ILE A 528VAL A 530 | None | 1.12A | 4tvtA-4btgA:undetectable | 4tvtA-4btgA:12.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bvt | CYANURIC ACIDAMIDOHYDROLASE (Pseudomonas sp.ADP) |
PF09663(Amido_AtzD_TrzD) | 4 | GLU A 207SER A 226ILE A 201VAL A 159 | None | 1.11A | 4tvtA-4bvtA:undetectable | 4tvtA-4bvtA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4clc | UPF0303 PROTEINYBR137W (Saccharomycescerevisiae) |
PF03928(Haem_degrading) | 4 | LEU E 164SER E 163ILE E 46VAL E 50 | None | 1.21A | 4tvtA-4clcE:undetectable | 4tvtA-4clcE:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fek | PUTATIVE DIFLAVINFLAVOPROTEIN A 5 (Nostoc sp. PCC7120) |
no annotation | 4 | LEU A 21SER A 45ILE A 55VAL A 83 | None | 1.11A | 4tvtA-4fekA:undetectable | 4tvtA-4fekA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4igu | CG5036 (Drosophilamelanogaster) |
PF00615(RGS) | 4 | LYS A 73LEU A 69GLU A 64SER A 66 | None | 0.96A | 4tvtA-4iguA:undetectable | 4tvtA-4iguA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iqg | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Polaromonas sp.JS666) |
no annotation | 4 | LEU C 21SER C 18ILE C 226VAL C 139 | None | 1.13A | 4tvtA-4iqgC:undetectable | 4tvtA-4iqgC:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jcc | IRON-COMPOUND ABCTRANSPORTER,IRON-COMPOUND-BINDING PROTEIN (Streptococcuspneumoniae) |
PF01497(Peripla_BP_2) | 4 | LEU A 161SER A 160ILE A 44VAL A 51 | None | 1.23A | 4tvtA-4jccA:undetectable | 4tvtA-4jccA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n83 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Streptococcussanguinis) |
PF00268(Ribonuc_red_sm) | 4 | LEU A 156GLU A 157SER A 153VAL A 74 | None MN A 401 ( 2.5A) MN A 401 ( 4.6A)None | 1.18A | 4tvtA-4n83A:undetectable | 4tvtA-4n83A:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ng3 | 5-CARBOXYVANILLATEDECARBOXYLASE (Sphingomonaspaucimobilis) |
PF04909(Amidohydro_2) | 4 | LEU A 168SER A 166ILE A 128VAL A 159 | None | 1.16A | 4tvtA-4ng3A:undetectable | 4tvtA-4ng3A:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nq3 | CYANURIC ACIDAMIDOHYDROLASE (Azorhizobiumcaulinodans) |
PF09663(Amido_AtzD_TrzD) | 4 | GLU A 201SER A 220ILE A 195VAL A 153 | None | 0.99A | 4tvtA-4nq3A:undetectable | 4tvtA-4nq3A:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nuz | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE F2 (Streptococcuspyogenes) |
no annotation | 4 | LEU A 962SER A 965ILE A 976VAL A 973 | None | 1.20A | 4tvtA-4nuzA:undetectable | 4tvtA-4nuzA:13.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qfk | ABC TRANSPORTERPERIPLASMICPEPTIDE-BINDINGPROTEIN (Pseudoalteromonassp. SM9913) |
no annotation | 4 | LEU H 521GLU H 285ILE H 519VAL H 516 | None | 1.05A | 4tvtA-4qfkH:undetectable | 4tvtA-4qfkH:17.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uml | GANGLIOSIDE-INDUCEDDIFFERENTIATION-ASSOCIATED PROTEIN 2 (Homo sapiens) |
PF01661(Macro) | 4 | LEU A 210GLU A 211SER A 208VAL A 85 | None | 1.13A | 4tvtA-4umlA:undetectable | 4tvtA-4umlA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uoo | LIPOTEICHOIC ACIDSYNTHASE (Listeriamonocytogenes) |
PF00884(Sulfatase) | 4 | LYS A 610LEU A 614GLU A 613SER A 617 | None | 1.11A | 4tvtA-4uooA:undetectable | 4tvtA-4uooA:17.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ux3 | STRUCTURALMAINTENANCE OFCHROMOSOMES PROTEIN3MITOTIC CHROMOSOMEDETERMINANT-RELATEDPROTEIN (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF02463(SMC_N)PF04825(Rad21_Rec8_N) | 4 | LEU A1019GLU A1018SER A1022ILE B 43 | None | 1.11A | 4tvtA-4ux3A:undetectable | 4tvtA-4ux3A:15.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x9t | UNCHARACTERIZEDPROTEIN UPF0065 (Polaromonas sp.JS666) |
PF03401(TctC) | 4 | LEU A 64SER A 56ILE A 271VAL A 272 | None | 1.10A | 4tvtA-4x9tA:undetectable | 4tvtA-4x9tA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yh7 | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE DELTA (Mus musculus) |
PF00041(fn3)PF07679(I-set)PF13927(Ig_3) | 4 | GLU A 80SER A 87ILE A 62VAL A 63 | None | 1.05A | 4tvtA-4yh7A:undetectable | 4tvtA-4yh7A:12.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z26 | PUTATIVE GMC-TYPEOXIDOREDUCTASE R135 (Acanthamoebapolyphagamimivirus) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | LEU A 307SER A 310ILE A 266VAL A 276 | None | 0.92A | 4tvtA-4z26A:undetectable | 4tvtA-4z26A:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a21 | PORTAL PROTEIN (Bacillus phageSPP1) |
PF05133(Phage_prot_Gp6) | 4 | LYS A 261LEU A 257SER A 255LYS A 140 | None | 0.88A | 4tvtA-5a21A:undetectable | 4tvtA-5a21A:17.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5amz | THAUMATIN-1 (Thaumatococcusdaniellii) |
PF00314(Thaumatin) | 7 | LYS A 49LEU A 87GLU A 89SER A 103ILE A 105LYS A 106VAL A 184 | None | 0.19A | 4tvtA-5amzA:40.9 | 4tvtA-5amzA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bqk | ICP27 (Humanalphaherpesvirus1) |
PF05459(Herpes_UL69) | 4 | LEU A 407SER A 427ILE A 422LYS A 423 | None | 1.14A | 4tvtA-5bqkA:undetectable | 4tvtA-5bqkA:23.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bqs | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Streptococcuspneumoniae) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | LYS A 133LEU A 165GLU A 167SER A 7 | None | 1.07A | 4tvtA-5bqsA:undetectable | 4tvtA-5bqsA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cer | BD0816 (Bdellovibriobacteriovorus) |
PF02113(Peptidase_S13) | 4 | GLU A 365SER A 358ILE A 343VAL A 322 | None | 1.09A | 4tvtA-5cerA:undetectable | 4tvtA-5cerA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cjj | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE (Campylobacterjejuni) |
PF00551(Formyl_trans_N) | 4 | LEU A 181GLU A 185SER A 182ILE A 178 | None | 1.18A | 4tvtA-5cjjA:undetectable | 4tvtA-5cjjA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cws | NUCLEOPORIN NUP57 (Chaetomiumthermophilum) |
PF13874(Nup54) | 4 | LYS E 224LEU E 223GLU E 220VAL E 208 | None | 1.15A | 4tvtA-5cwsE:undetectable | 4tvtA-5cwsE:17.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dbj | FADH2-DEPENDENTHALOGENASE PLTA (Pseudomonasprotegens) |
no annotation | 4 | LEU E 104GLU E 107ILE E 103VAL E 389 | None | 1.19A | 4tvtA-5dbjE:undetectable | 4tvtA-5dbjE:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9u | GLYCOSYLTRANSFERASEGTF1GLYCOSYLTRANSFERASE-STABILIZING PROTEINGTF2 (Streptococcusgordonii;Streptococcusgordonii) |
PF00534(Glycos_transf_1)no annotation | 4 | LYS B 129LEU B 116GLU B 118ILE A 193 | None | 1.19A | 4tvtA-5e9uB:undetectable | 4tvtA-5e9uB:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eb5 | HNL ISOENZYME 5 (Prunus dulcis) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | LEU A 267SER A 270ILE A 220VAL A 234 | None | 0.94A | 4tvtA-5eb5A:undetectable | 4tvtA-5eb5A:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fsa | CYP51 VARIANT1 (Candidaalbicans) |
PF00067(p450) | 4 | LEU A 359GLU A 336SER A 361ILE A 333 | None | 1.22A | 4tvtA-5fsaA:undetectable | 4tvtA-5fsaA:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fv5 | KPFLO11A1 (Komagataellaphaffii) |
PF10182(Flo11) | 4 | LYS A 84LEU A 97GLU A 82SER A 100 | None | 1.14A | 4tvtA-5fv5A:undetectable | 4tvtA-5fv5A:25.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fwh | ESSC (Geobacillusthermodenitrificans) |
PF12538(FtsK_SpoIIIE_N) | 4 | GLU A 105SER A 124ILE A 135VAL A 133 | None | 1.10A | 4tvtA-5fwhA:undetectable | 4tvtA-5fwhA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gje | LOW-DENSITYLIPOPROTEINRECEPTOR-RELATEDPROTEIN 6 (Homo sapiens) |
PF00058(Ldl_recept_b)PF14670(FXa_inhibition) | 4 | LEU B1076ILE B1105LYS B1103VAL B1148 | None | 1.21A | 4tvtA-5gjeB:undetectable | 4tvtA-5gjeB:16.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hxz | BARBITURASE (Rhodococcuserythropolis) |
PF09663(Amido_AtzD_TrzD) | 4 | GLU A 207SER A 224ILE A 201VAL A 159 | None | 1.07A | 4tvtA-5hxzA:undetectable | 4tvtA-5hxzA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i68 | ALCOHOL OXIDASE 1 (Komagataellapastoris) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | LEU A 277SER A 280ILE A 230VAL A 240 | None | 0.92A | 4tvtA-5i68A:undetectable | 4tvtA-5i68A:15.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lnk | MITOCHONDRIALCOMPLEX I, ND5SUBUNITMITOCHONDRIALCOMPLEX I, B17SUBUNIT (Ovis aries;Ovis aries) |
PF00361(Proton_antipo_M)PF00662(Proton_antipo_N)PF06455(NADH5_C)no annotation | 4 | SER L 79ILE L 62LYS L 81VAL r 97 | None | 1.22A | 4tvtA-5lnkL:undetectable | 4tvtA-5lnkL:15.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m2d | ENDOGLUCANASE-LIKEPROTEIN (Acremoniumchrysogenum) |
no annotation | 4 | LEU A 79SER A 82ILE A 83VAL A 225 | None | 1.23A | 4tvtA-5m2dA:undetectable | 4tvtA-5m2dA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5odr | METHYL-VIOLOGENREDUCINGHYDROGENASE, SUBUNITDMETHYL-VIOLOGENREDUCINGHYDROGENASE, SUBUNITG (Methanothermococcusthermolithotrophicus;Methanothermococcusthermolithotrophicus) |
PF02662(FlpD)PF01058(Oxidored_q6) | 4 | LEU D 50GLU D 47SER D 49VAL E 245 | None | 1.23A | 4tvtA-5odrD:undetectable | 4tvtA-5odrD:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oko | PHOSPHATIDYLINOSITOL3,4,5-TRISPHOSPHATE5-PHOSPHATASE 2 (Homo sapiens) |
PF03372(Exo_endo_phos) | 4 | LEU A 803SER A 780ILE A 767VAL A 825 | None | 1.03A | 4tvtA-5okoA:undetectable | 4tvtA-5okoA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t13 | CYANURIC ACIDAMIDOHYDROLASE (Enterobactercloacae) |
PF09663(Amido_AtzD_TrzD) | 4 | GLU A 208SER A 227ILE A 202VAL A 160 | None | 0.94A | 4tvtA-5t13A:undetectable | 4tvtA-5t13A:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w3v | APOBEC3H (Macacanemestrina) |
no annotation | 4 | LYS B 162LEU B 166GLU B 165VAL B 19 | NoneNoneNone A F 2 ( 4.8A) | 0.98A | 4tvtA-5w3vB:undetectable | 4tvtA-5w3vB:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xa2 | CYSTEINE SYNTHASE (Planctopiruslimnophila) |
PF00291(PALP) | 4 | LEU A 26SER A 28ILE A 288VAL A 171 | None | 1.01A | 4tvtA-5xa2A:undetectable | 4tvtA-5xa2A:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y3r | X-RAY REPAIRCROSS-COMPLEMENTINGPROTEIN 6 (Homo sapiens) |
PF02735(Ku)PF03730(Ku_C)PF03731(Ku_N) | 4 | LEU A 381SER A 378ILE A 269VAL A 271 | None | 0.84A | 4tvtA-5y3rA:undetectable | 4tvtA-5y3rA:16.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y8p | PROBABLE3-HYDROXYISOBUTYRATEDEHYDROGENASE (Mycobacteriumtuberculosis) |
no annotation | 4 | LYS A 243LEU A 247ILE A 94VAL A 71 | None | 1.22A | 4tvtA-5y8pA:undetectable | 4tvtA-5y8pA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bfi | VIN1 (Oscarellapearsei) |
no annotation | 4 | GLU A 566SER A 565LYS A 546VAL A 558 | None | 1.05A | 4tvtA-6bfiA:undetectable | 4tvtA-6bfiA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MBH SUBUNIT (Pyrococcusfuriosus) |
no annotation | 4 | LEU D 53GLU D 69SER D 50VAL D 77 | None | 1.21A | 4tvtA-6cfwD:undetectable | 4tvtA-6cfwD:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d6r | EXOSOME COMPLEXCOMPONENT CSL4 (Homo sapiens) |
no annotation | 4 | LEU I 88ILE I 127LYS I 74VAL I 155 | None | 0.77A | 4tvtA-6d6rI:undetectable | 4tvtA-6d6rI:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6en3 | ENDO-BETA-N-ACETYLGLUCOSAMINIDASEF2,MULTIFUNCTIONAL-AUTOPROCESSINGREPEATS-IN-TOXIN (Vibriocholerae;Streptococcuspyogenes) |
no annotation | 4 | LEU A 962SER A 965ILE A 976VAL A 973 | None | 1.23A | 4tvtA-6en3A:undetectable | 4tvtA-6en3A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6evj | RNA-DIRECTED RNAPOLYMERASE CATALYTICSUBUNIT (Influenza Avirus) |
no annotation | 4 | LEU B 298ILE B 459LYS B 456VAL B 463 | None | 1.00A | 4tvtA-6evjB:undetectable | 4tvtA-6evjB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f0k | POLYSULPHIDEREDUCTASE NRFDACTD (Rhodothermusmarinus;Rhodothermusmarinus) |
no annotationno annotation | 4 | LEU C 242GLU D 122SER C 245VAL C 250 | None | 1.08A | 4tvtA-6f0kC:undetectable | 4tvtA-6f0kC:undetectable |