SIMILAR PATTERNS OF AMINO ACIDS FOR 4TNS_A_REAA201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1nmw PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
NIMA-INTERACTING 1

(Homo sapiens) 		PF00639
(Rotamase) 		5 HIS A  59
LYS A  63
MET A 130
PHE A 134
SER A 154
 None
SO4  A 200 (-3.1A)
None
None
SO4  A 200 (-4.1A)
 0.93A 4tnsA-1nmwA:
20.2		 4tnsA-1nmwA:
98.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1yw5 PEPTIDYL PROLYL
CIS/TRANS ISOMERASE

(Candida
albicans) 		PF00397
(WW)
PF00639
(Rotamase) 		7 HIS A  72
LYS A  76
MET A 144
GLN A 145
PHE A 148
SER A 168
HIS A 171
 None
 0.28A 4tnsA-1yw5A:
22.7		 4tnsA-1yw5A:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zcn PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
NIMA-INTERACTING 1

(Homo sapiens) 		PF00397
(WW)
PF00639
(Rotamase) 		8 HIS A  59
LYS A  63
ARG A  68
MET A 130
GLN A 131
PHE A 134
SER A 154
HIS A 157
 1PE  A 400 ( 4.4A)
PO4  A 321 (-2.6A)
PO4  A 321 (-3.8A)
1PE  A 400 (-3.8A)
1PE  A 400 (-4.5A)
1PE  A 400 (-3.7A)
PO4  A 321 (-2.7A)
1PE  A 400 ( 4.7A)
 0.28A 4tnsA-1zcnA:
24.7		 4tnsA-1zcnA:
77.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2lj4 PEPTIDYL-PROLYL
CIS-TRANS
ISOMERASE/ROTAMASE,
PUTATIVE

(Trypanosoma
brucei) 		PF00639
(Rotamase) 		5 HIS A  12
LYS A  16
MET A  85
PHE A  89
HIS A 112
 None
 1.04A 4tnsA-2lj4A:
18.2		 4tnsA-2lj4A:
39.87