SIMILAR PATTERNS OF AMINO ACIDS FOR 4RTB_A_SAMA501_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1evs ONCOSTATIN M

(Homo sapiens) 		PF01291
(LIF_OSM) 		3 GLU A  59
ARG A  63
GLN A  25
 None
 0.81A 4rtbA-1evsA:
undetectable		 4rtbA-1evsA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f7u ARGINYL-TRNA
SYNTHETASE

(Saccharomyces
cerevisiae) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		3 GLU A 294
ARG A 350
GLN A 375
 A  B 976 ( 2.6A)
A  B 976 ( 3.1A)
ARG  A 800 (-3.5A)
 0.94A 4rtbA-1f7uA:
undetectable		 4rtbA-1f7uA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8x MYOSIN II HEAVY
CHAIN FUSED TO
ALPHA-ACTININ 3

(Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		3 GLU A 238
ARG A 267
GLN A 468
 None
 0.96A 4rtbA-1g8xA:
undetectable		 4rtbA-1g8xA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iqr PHOTOLYASE

(Thermus
thermophilus) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		3 GLU A 244
ARG A 201
GLN A 349
 FAD  A 421 (-4.4A)
None
FAD  A 421 (-3.7A)
 0.53A 4rtbA-1iqrA:
undetectable		 4rtbA-1iqrA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pdr HUMAN DISCS LARGE
PROTEIN

(Homo sapiens) 		PF00595
(PDZ) 		3 GLU A 549
ARG A 552
GLN A 544
 None
 0.91A 4rtbA-1pdrA:
undetectable		 4rtbA-1pdrA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1px5 2'-5'-OLIGOADENYLATE
SYNTHETASE 1

(Sus scrofa) 		PF01909
(NTP_transf_2)
PF10421
(OAS1_C) 		3 GLU A 111
ARG A 110
GLN A  46
 None
 0.79A 4rtbA-1px5A:
undetectable		 4rtbA-1px5A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q32 TYROSYL-DNA
PHOSPHODIESTERASE

(Saccharomyces
cerevisiae) 		PF06087
(Tyr-DNA_phospho) 		3 GLU A 323
ARG A 321
GLN A 468
 None
 0.97A 4rtbA-1q32A:
undetectable		 4rtbA-1q32A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qas PHOSPHOLIPASE C
DELTA-1

(Rattus
norvegicus) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		3 GLU A 341
ARG A 549
GLN A 319
 None
 0.96A 4rtbA-1qasA:
3.4		 4rtbA-1qasA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qhg ATP-DEPENDENT
HELICASE PCRA

(Geobacillus
stearothermophilus) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C) 		3 GLU A 301
ARG A 306
GLN A 294
 None
 0.87A 4rtbA-1qhgA:
undetectable		 4rtbA-1qhgA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qhh PROTEIN (PCRA
(SUBUNIT))

(Geobacillus
stearothermophilus) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C) 		3 GLU B 301
ARG B 306
GLN B 294
 None
 0.86A 4rtbA-1qhhB:
undetectable		 4rtbA-1qhhB:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sky F1-ATPASE

(Bacillus sp.
PS3) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		3 GLU E 190
ARG E 191
GLN E 259
 None
 0.92A 4rtbA-1skyE:
undetectable		 4rtbA-1skyE:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vav ALGINATE LYASE
PA1167

(Pseudomonas
aeruginosa) 		PF08787
(Alginate_lyase2) 		3 GLU A  90
ARG A  88
GLN A  35
 None
 0.83A 4rtbA-1vavA:
undetectable		 4rtbA-1vavA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wgo VPS10
DOMAIN-CONTAINING
RECEPTOR SORCS2

(Homo sapiens) 		PF00801
(PKD) 		3 GLU A 103
ARG A 101
GLN A  18
 None
 0.89A 4rtbA-1wgoA:
undetectable		 4rtbA-1wgoA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yg2 GENE ACTIVATOR APHA

(Vibrio cholerae) 		PF03551
(PadR)
PF10400
(Vir_act_alpha_C) 		3 GLU A 133
ARG A 151
GLN A 162
 None
 0.78A 4rtbA-1yg2A:
undetectable		 4rtbA-1yg2A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ykd ADENYLATE CYCLASE

(Anabaena sp.) 		PF01590
(GAF) 		3 GLU A 130
ARG A 132
GLN A  85
 None
 0.94A 4rtbA-1ykdA:
undetectable		 4rtbA-1ykdA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z7c CHORIONIC
SOMATOMAMMOTROPIN
HORMONE

(Homo sapiens) 		PF00103
(Hormone_1) 		3 GLU A 174
ARG A 178
GLN A  22
 None
 0.97A 4rtbA-1z7cA:
undetectable		 4rtbA-1z7cA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ewo PUTATIVE AGMATINE
DEIMINASE

(Streptococcus
mutans) 		PF04371
(PAD_porph) 		3 GLU A 350
ARG A 348
GLN A 284
 None
 0.95A 4rtbA-2ewoA:
undetectable		 4rtbA-2ewoA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gl5 PUTATIVE DEHYDRATASE
PROTEIN

(Salmonella
enterica) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 GLU A 274
ARG A 275
GLN A 134
 MG  A 699 (-2.6A)
None
MG  A 699 ( 4.9A)
 0.90A 4rtbA-2gl5A:
5.4		 4rtbA-2gl5A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hgs PROTEIN (GLUTATHIONE
SYNTHETASE)

(Homo sapiens) 		PF03199
(GSH_synthase)
PF03917
(GSH_synth_ATP) 		3 GLU A 425
ARG A 450
GLN A 308
 ADP  A 500 (-2.6A)
SO4  A 505 ( 3.1A)
None
 0.90A 4rtbA-2hgsA:
undetectable		 4rtbA-2hgsA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hlw UBIQUITIN-CONJUGATIN
G ENZYME E2 VARIANT
1

(Homo sapiens) 		PF00179
(UQ_con) 		3 GLU A 146
ARG A 149
GLN A 135
 None
 0.86A 4rtbA-2hlwA:
undetectable		 4rtbA-2hlwA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i34 ACID PHOSPHATASE

(Bacillus
anthracis) 		PF03767
(Acid_phosphat_B) 		3 GLU A 223
ARG A 242
GLN A  77
 None
 0.94A 4rtbA-2i34A:
undetectable		 4rtbA-2i34A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o4c ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
PF11890
(DUF3410) 		3 GLU A 222
ARG A 247
GLN A 215
 None
 0.97A 4rtbA-2o4cA:
undetectable		 4rtbA-2o4cA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o56 PUTATIVE MANDELATE
RACEMASE

(Salmonella
enterica) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 GLU A 271
ARG A 272
GLN A 134
 MG  A2001 (-2.6A)
None
None
 0.76A 4rtbA-2o56A:
5.2		 4rtbA-2o56A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ox4 PUTATIVE MANDELATE
RACEMASE

(Zymomonas
mobilis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 GLU A 265
ARG A 266
GLN A 130
 MG  A 402 (-2.5A)
None
None
 0.82A 4rtbA-2ox4A:
5.2		 4rtbA-2ox4A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xiv HYPOTHETICAL
INVASION PROTEIN

(Mycobacterium
tuberculosis) 		PF00877
(NLPC_P60) 		3 GLU A 444
ARG A 453
GLN A 431
 None
 0.79A 4rtbA-2xivA:
undetectable		 4rtbA-2xivA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c0k UPF0064 PROTEIN YCCW

(Escherichia
coli) 		PF10672
(Methyltrans_SAM) 		3 GLU A 292
ARG A 290
GLN A 245
 None
 0.71A 4rtbA-3c0kA:
undetectable		 4rtbA-3c0kA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dip ENOLASE

(unidentified) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 GLU A  22
ARG A   8
GLN A  99
 None
 0.96A 4rtbA-3dipA:
4.5		 4rtbA-3dipA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3djd FRUCTOSYL AMINE:
OXYGEN
OXIDOREDUCTASE

(Aspergillus
fumigatus) 		PF01266
(DAO) 		3 GLU A 310
ARG A 314
GLN A 304
 None
 0.91A 4rtbA-3djdA:
undetectable		 4rtbA-3djdA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f0n MEVALONATE
PYROPHOSPHATE
DECARBOXYLASE

(Mus musculus) 		PF00288
(GHMP_kinases_N) 		3 GLU A 150
ARG A 154
GLN A 175
 None
 0.92A 4rtbA-3f0nA:
undetectable		 4rtbA-3f0nA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fg6 ADSEVERIN

(Homo sapiens) 		PF00626
(Gelsolin) 		3 GLU A 563
ARG A 579
GLN A 608
 None
 0.97A 4rtbA-3fg6A:
undetectable		 4rtbA-3fg6A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3flo DNA POLYMERASE ALPHA
SUBUNIT B

(Saccharomyces
cerevisiae) 		PF04042
(DNA_pol_E_B)
PF08418
(Pol_alpha_B_N) 		3 GLU A 319
ARG A 329
GLN A 264
 None
 0.94A 4rtbA-3floA:
2.2		 4rtbA-3floA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fym PUTATIVE
UNCHARACTERIZED
PROTEIN

(Staphylococcus
aureus) 		PF13413
(HTH_25) 		3 GLU A1051
ARG A1055
GLN A1073
 None
 0.73A 4rtbA-3fymA:
undetectable		 4rtbA-3fymA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g25 GLYCEROL KINASE

(Staphylococcus
aureus) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		3 GLU A 120
ARG A 124
GLN A 108
 None
 0.95A 4rtbA-3g25A:
undetectable		 4rtbA-3g25A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iug RHO/CDC42/RAC
GTPASE-ACTIVATING
PROTEIN RICS

(Homo sapiens) 		PF00620
(RhoGAP) 		3 GLU A 498
ARG A 502
GLN A 487
 None
 0.72A 4rtbA-3iugA:
undetectable		 4rtbA-3iugA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kbh ANGIOTENSIN-CONVERTI
NG ENZYME 2

(Homo sapiens) 		PF01401
(Peptidase_M2) 		3 GLU A 406
ARG A 518
GLN A 442
 None
 0.84A 4rtbA-3kbhA:
undetectable		 4rtbA-3kbhA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3khd PYRUVATE KINASE

(Plasmodium
falciparum) 		PF00224
(PK)
PF02887
(PK_C) 		3 GLU A 404
ARG A 408
GLN A 314
 None
 0.78A 4rtbA-3khdA:
2.2		 4rtbA-3khdA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kkd TRANSCRIPTIONAL
REGULATOR

(Pseudomonas
aeruginosa) 		PF00440
(TetR_N) 		3 GLU A 132
ARG A 129
GLN A 139
 None
 0.96A 4rtbA-3kkdA:
undetectable		 4rtbA-3kkdA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nv3 GALECTIN 9 SHORT
ISOFORM VARIANT

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		3 GLU A 311
ARG A 309
GLN A 250
 None
 0.94A 4rtbA-3nv3A:
undetectable		 4rtbA-3nv3A:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qnq PTS SYSTEM,
CELLOBIOSE-SPECIFIC
IIC COMPONENT

(Bacillus cereus) 		PF02378
(PTS_EIIC) 		3 GLU A 158
ARG A 161
GLN A  19
 None
 0.94A 4rtbA-3qnqA:
undetectable		 4rtbA-3qnqA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rap PROTEIN (G PROTEIN
RAP2A)

(Homo sapiens) 		PF00071
(Ras) 		3 GLU R  54
ARG R  41
GLN R  76
 None
 0.96A 4rtbA-3rapR:
undetectable		 4rtbA-3rapR:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s95 LIM DOMAIN KINASE 1

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 GLU A 630
ARG A 633
GLN A 623
 None
 0.88A 4rtbA-3s95A:
undetectable		 4rtbA-3s95A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t33 G PROTEIN COUPLED
RECEPTOR

(Arabidopsis
thaliana) 		PF05147
(LANC_like) 		3 GLU A 199
ARG A 169
GLN A 206
 None
 0.82A 4rtbA-3t33A:
undetectable		 4rtbA-3t33A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tex PROTECTIVE ANTIGEN

(Bacillus
anthracis) 		PF03495
(Binary_toxB)
PF07691
(PA14)
PF17475
(Binary_toxB_2)
PF17476
(Binary_toxB_3) 		3 GLU A 502
ARG A 297
GLN A 485
 None
 0.87A 4rtbA-3texA:
undetectable		 4rtbA-3texA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqv NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE

(Francisella
tularensis) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		3 GLU A 107
ARG A 108
GLN A 284
 None
 0.96A 4rtbA-3tqvA:
2.5		 4rtbA-3tqvA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u1k POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE 1, MITOCHONDRIAL

(Homo sapiens) 		PF00013
(KH_1)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		3 GLU A 164
ARG A 192
GLN A 104
 None
 0.83A 4rtbA-3u1kA:
undetectable		 4rtbA-3u1kA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umg HALOACID
DEHALOGENASE

(Rhodococcus
jostii) 		PF00702
(Hydrolase) 		3 GLU A 188
ARG A  13
GLN A 180
 None
 0.96A 4rtbA-3umgA:
undetectable		 4rtbA-3umgA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uy4 PANTOTHENATE
SYNTHETASE

(Campylobacter
jejuni) 		PF02569
(Pantoate_ligase) 		3 GLU A 209
ARG A 213
GLN A 147
 None
 0.88A 4rtbA-3uy4A:
undetectable		 4rtbA-3uy4A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vnp HYPOTHETICAL
CONSERVED PROTEIN

(Geobacillus
kaustophilus) 		PF00132
(Hexapep) 		3 GLU A 157
ARG A 153
GLN A  58
 None
 0.96A 4rtbA-3vnpA:
undetectable		 4rtbA-3vnpA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wc3 ENDO-1,
4-BETA-GLUCANASE

(Eisenia fetida) 		PF00759
(Glyco_hydro_9) 		3 GLU A  37
ARG A  40
GLN A 108
 None
 0.86A 4rtbA-3wc3A:
undetectable		 4rtbA-3wc3A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wiw GLYCOSYL HYDROLASE
FAMILY 88

(Pedobacter
heparinus) 		PF07470
(Glyco_hydro_88) 		3 GLU A 369
ARG A  66
GLN A 236
 None
None
EPE  A 501 ( 4.3A)
 0.90A 4rtbA-3wiwA:
undetectable		 4rtbA-3wiwA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wo0 ALANINE-ANTICAPSIN
LIGASE BACD

(Bacillus
subtilis) 		PF13535
(ATP-grasp_4) 		3 GLU A 220
ARG A 157
GLN A 130
 None
 0.90A 4rtbA-3wo0A:
undetectable		 4rtbA-3wo0A:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdj ENCA BETA-LACTAMASE

(synthetic
construct) 		PF13354
(Beta-lactamase2) 		3 GLU A  48
ARG A 259
GLN A  28
 None
 0.95A 4rtbA-3zdjA:
undetectable		 4rtbA-3zdjA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ayg GLUCANSUCRASE

(Lactobacillus
reuteri) 		PF01473
(CW_binding_1)
PF02324
(Glyco_hydro_70) 		3 GLU A1407
ARG A1202
GLN A1140
 None
None
GOL  A2773 ( 4.8A)
 0.86A 4rtbA-4aygA:
3.0		 4rtbA-4aygA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ayr MANNOSYL-OLIGOSACCHA
RIDE
1,2-ALPHA-MANNOSIDAS
E

(Caulobacter sp.
K31) 		PF01532
(Glyco_hydro_47) 		3 GLU A 452
ARG A 125
GLN A 428
 IFL  A 503 (-3.1A)
IFL  A 503 ( 4.1A)
None
 0.91A 4rtbA-4ayrA:
undetectable		 4rtbA-4ayrA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ecn LEUCINE-RICH REPEAT
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF14660
(DUF4458) 		3 GLU A 294
ARG A 352
GLN A 507
 None
 0.65A 4rtbA-4ecnA:
undetectable		 4rtbA-4ecnA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eco UNCHARACTERIZED
PROTEIN

(Bacteroides
eggerthii) 		no annotation 3 GLU A 295
ARG A 350
GLN A 505
 None
 0.73A 4rtbA-4ecoA:
undetectable		 4rtbA-4ecoA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4izg MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME,
N-TERMINAL DOMAIN
PROTEIN

(Paracoccus
denitrificans) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 GLU A 243
ARG A 269
GLN A 162
 MG  A 414 ( 4.3A)
None
4OP  A 416 (-3.0A)
 0.97A 4rtbA-4izgA:
7.1		 4rtbA-4izgA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kk1 TUBEROUS SCLEROSIS 1
PROTEIN HOMOLOG

(Schizosaccharomyces
pombe) 		PF04388
(Hamartin) 		3 GLU A 130
ARG A 136
GLN A  36
 None
 0.92A 4rtbA-4kk1A:
undetectable		 4rtbA-4kk1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m75 U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM1
U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM2

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF01423
(LSM)
PF01423
(LSM) 		3 GLU A 114
ARG A  52
GLN B  30
 None
 0.88A 4rtbA-4m75A:
undetectable		 4rtbA-4m75A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00583
(Acetyltransf_1)
PF10394
(Hat1_N)
PF00400
(WD40)
PF12265
(CAF1C_H4-bd) 		3 GLU A 304
ARG A 297
GLN B 327
 None
 0.79A 4rtbA-4pswA:
undetectable		 4rtbA-4pswA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q4g PEPTIDOGLYCAN
ENDOPEPTIDASE RIPA

(Mycobacterium
tuberculosis) 		PF00877
(NLPC_P60) 		3 GLU X1182
ARG X1191
GLN X1169
 None
 0.79A 4rtbA-4q4gX:
undetectable		 4rtbA-4q4gX:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r33 NOSL

(Streptomyces
actuosus) 		PF06968
(BATS) 		3 GLU A 204
ARG A 230
GLN A 363
 SAH  A 501 (-2.7A)
SAH  A 501 (-2.9A)
SAH  A 501 (-3.2A)
 0.61A 4rtbA-4r33A:
39.8		 4rtbA-4r33A:
29.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r61 GP41-BASED CONSTRUCT
COVNHR3-ABC

(Human
immunodeficiency
virus 1) 		no annotation 3 GLU A  91
ARG A  94
GLN A  84
 None
 0.70A 4rtbA-4r61A:
undetectable		 4rtbA-4r61A:
17.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4rtb HYDG PROTEIN

(Carboxydothermus
hydrogenoformans) 		PF04055
(Radical_SAM)
PF06968
(BATS) 		3 GLU A 189
ARG A 211
GLN A 346
 SAM  A 501 (-2.4A)
SAM  A 501 (-2.7A)
SAM  A 501 (-3.1A)
 0.01A 4rtbA-4rtbA:
71.5		 4rtbA-4rtbA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v02 PROBABLE SEPTUM
SITE-DETERMINING
PROTEIN MINC

(Aquifex
aeolicus) 		PF03775
(MinC_C) 		3 GLU C 116
ARG C  98
GLN C 156
 None
 0.82A 4rtbA-4v02C:
undetectable		 4rtbA-4v02C:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wsh UROPORPHYRINOGEN
DECARBOXYLASE

(Pseudomonas
aeruginosa) 		PF01208
(URO-D) 		3 GLU A 262
ARG A 286
GLN A 221
 None
 0.94A 4rtbA-4wshA:
7.4		 4rtbA-4wshA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgc ORIGIN RECOGNITION
COMPLEX SUBUNIT 1
ORIGIN RECOGNITION
COMPLEX SUBUNIT 2

(Drosophila
melanogaster;
Drosophila
melanogaster) 		PF00004
(AAA)
PF09079
(Cdc6_C)
PF04084
(ORC2) 		3 GLU A 639
ARG A 693
GLN B 577
 None
 0.95A 4rtbA-4xgcA:
undetectable		 4rtbA-4xgcA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xm4 MEX67

(Chaetomium
thermophilum) 		no annotation 3 GLU A 511
ARG A 522
GLN A 516
 GLU  A 511 ( 0.5A)
ARG  A 522 ( 0.6A)
GLN  A 516 ( 0.6A)
 0.93A 4rtbA-4xm4A:
undetectable		 4rtbA-4xm4A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM

(Escherichia
coli) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF11974
(MG1) 		3 GLU A 793
ARG A 820
GLN A 471
 None
 0.97A 4rtbA-5a42A:
undetectable		 4rtbA-5a42A:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5azs OUTER MEMBRANE
PROTEIN OPRJ

(Pseudomonas
aeruginosa) 		PF02321
(OEP) 		3 GLU A 120
ARG A 295
GLN A  75
 None
 0.81A 4rtbA-5azsA:
undetectable		 4rtbA-5azsA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b86 TUMOR NECROSIS
FACTOR ALPHA-INDUCED
PROTEIN 2

(Mus musculus) 		PF06046
(Sec6) 		3 GLU A 355
ARG A 338
GLN A 362
 None
 0.88A 4rtbA-5b86A:
undetectable		 4rtbA-5b86A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cj3 ZBM BINDING PROTEIN

(Streptomyces
flavoviridis) 		no annotation 3 GLU A 105
ARG A  98
GLN A  63
 52G  A 201 ( 4.9A)
52G  A 201 (-3.8A)
52G  A 201 ( 3.9A)
 0.96A 4rtbA-5cj3A:
undetectable		 4rtbA-5cj3A:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csu 4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC

(Arabidopsis
thaliana) 		PF02446
(Glyco_hydro_77) 		3 GLU A 420
ARG A 371
GLN A 336
 AGL  A 607 ( 2.7A)
HMC  A 606 ( 3.7A)
AGL  A 607 ( 3.6A)
 0.97A 4rtbA-5csuA:
4.3		 4rtbA-5csuA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dot CARBAMOYL-PHOSPHATE
SYNTHASE [AMMONIA],
MITOCHONDRIAL

(Homo sapiens) 		PF00117
(GATase)
PF00988
(CPSase_sm_chain)
PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		3 GLU A1034
ARG A1039
GLN A 916
 EDO  A1603 (-2.7A)
EDO  A1603 ( 3.8A)
None
 0.84A 4rtbA-5dotA:
undetectable		 4rtbA-5dotA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5edu MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HISTONE DEACETYLASE
6 CHIMERA

(Escherichia
coli;
Homo sapiens) 		no annotation 3 GLU B 733
ARG B 773
GLN B 260
 None
 0.87A 4rtbA-5eduB:
undetectable		 4rtbA-5eduB:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fcc HUTD

(Pseudomonas
fluorescens) 		PF05962
(HutD) 		3 GLU A  25
ARG A  14
GLN A  67
 None
 0.85A 4rtbA-5fccA:
undetectable		 4rtbA-5fccA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fcs DIABODY
DIABODY

(Homo sapiens;
Homo sapiens) 		PF07686
(V-set)
PF07686
(V-set) 		3 GLU L 164
ARG L 156
GLN H   1
 None
 0.96A 4rtbA-5fcsL:
undetectable		 4rtbA-5fcsL:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw5 T-COMPLEX PROTEIN 1
SUBUNIT BETA

(Saccharomyces
cerevisiae) 		PF00118
(Cpn60_TCP1) 		3 GLU b  12
ARG b  14
GLN b   4
 None
 0.89A 4rtbA-5gw5b:
undetectable		 4rtbA-5gw5b:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hqb ALPHA-GLUCOSIDASE

(Pseudoalteromonas
sp. K8) 		PF10566
(Glyco_hydro_97)
PF14508
(GH97_N)
PF14509
(GH97_C) 		3 GLU A 132
ARG A 130
GLN A  79
 None
None
FMT  A 714 (-3.2A)
 0.93A 4rtbA-5hqbA:
6.8		 4rtbA-5hqbA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iaa UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME 5

(Homo sapiens) 		PF00899
(ThiF) 		3 GLU A  90
ARG A  94
GLN A 119
 None
 0.77A 4rtbA-5iaaA:
undetectable		 4rtbA-5iaaA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iy9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB4
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB7

(Homo sapiens;
Homo sapiens) 		PF03874
(RNA_pol_Rpb4)
PF00575
(S1)
PF03876
(SHS2_Rpb7-N) 		3 GLU D 110
ARG G 144
GLN D 135
 None
 0.88A 4rtbA-5iy9D:
undetectable		 4rtbA-5iy9D:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jem INTERFERON
REGULATORY FACTOR 3
CREB-BINDING PROTEIN

(Homo sapiens;
Homo sapiens) 		PF10401
(IRF-3)
PF09030
(Creb_binding)
PF11707
(Npa1) 		3 GLU A 377
ARG A 380
GLN C2082
 None
 0.76A 4rtbA-5jemA:
undetectable		 4rtbA-5jemA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jp9 CMP
5-HYDROXYMETHYLASE

(Streptomyces
rimofaciens) 		PF00303
(Thymidylat_synt) 		3 GLU A 195
ARG A 199
GLN A  50
 None
 0.82A 4rtbA-5jp9A:
undetectable		 4rtbA-5jp9A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxm PRIB

(Streptomyces
sp. RM-5-8) 		PF11991
(Trp_DMAT) 		3 GLU A 300
ARG A 371
GLN A 207
 None
 0.86A 4rtbA-5jxmA:
undetectable		 4rtbA-5jxmA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l46 DIMETHYLGLYCINE
DEHYDROGENASE,
MITOCHONDRIAL

(Homo sapiens) 		PF01266
(DAO)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF16350
(FAO_M) 		3 GLU A 460
ARG A 462
GLN A 150
 None
 0.83A 4rtbA-5l46A:
undetectable		 4rtbA-5l46A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lg4 PROTEIN SSO2

(Saccharomyces
cerevisiae) 		PF00804
(Syntaxin) 		3 GLU A  77
ARG A  81
GLN A  71
 None
 0.65A 4rtbA-5lg4A:
undetectable		 4rtbA-5lg4A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lv9 THERMOPHILIC
TRYPTOPHAN
HALOGENASE

(Streptomyces
violaceusniger) 		PF04820
(Trp_halogenase) 		3 GLU A  57
ARG A  53
GLN A 155
 None
 0.97A 4rtbA-5lv9A:
undetectable		 4rtbA-5lv9A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mz6 SEPARASE

(Caenorhabditis
elegans) 		PF03568
(Peptidase_C50) 		3 GLU 1 518
ARG 1 559
GLN 1 353
 None
 0.91A 4rtbA-5mz61:
undetectable		 4rtbA-5mz61:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oih -

(-) 		no annotation 3 GLU A 396
ARG A 399
GLN A 391
 None
 0.91A 4rtbA-5oihA:
undetectable		 4rtbA-5oihA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5thz CURJ

(Moorea
producens) 		no annotation 3 GLU B 225
ARG B 200
GLN B 252
 None
 0.96A 4rtbA-5thzB:
undetectable		 4rtbA-5thzB:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubp LEUCINE PERMEASE
TRANSCRIPTIONAL
REGULATOR

(Saccharomyces
cerevisiae) 		PF03399
(SAC3_GANP) 		3 GLU A 208
ARG A 211
GLN A 292
 None
 0.90A 4rtbA-5ubpA:
undetectable		 4rtbA-5ubpA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uqd DUMPY: SHORTER THAN
WILD-TYPE

(Caenorhabditis
elegans) 		no annotation 3 GLU A1519
ARG A1522
GLN A1257
 None
 0.90A 4rtbA-5uqdA:
undetectable		 4rtbA-5uqdA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v9x ATP-DEPENDENT DNA
HELICASE

(Mycolicibacterium
smegmatis) 		no annotation 3 GLU A  93
ARG A  97
GLN A 130
 None
 0.71A 4rtbA-5v9xA:
undetectable		 4rtbA-5v9xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vha DEAH
(ASP-GLU-ALA-HIS)
BOX POLYPEPTIDE 36

(Bos taurus) 		no annotation 3 GLU A 805
ARG A 816
GLN A 535
 None
 0.91A 4rtbA-5vhaA:
undetectable		 4rtbA-5vhaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xtc NADH DEHYDROGENASE
[UBIQUINONE] 1
SUBUNIT C1,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 3 GLU f  68
ARG f  71
GLN f  61
 None
 0.97A 4rtbA-5xtcf:
undetectable		 4rtbA-5xtcf:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)

(Acinetobacter
baumannii) 		no annotation 3 GLU A 128
ARG A 139
GLN A 310
 None
None
UDP  A 402 (-4.0A)
 0.94A 4rtbA-5xvsA:
undetectable		 4rtbA-5xvsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c66 CRISPR-ASSOCIATED
PROTEIN, CSE3 FAMILY

(Thermobifida
fusca) 		no annotation 3 GLU O  56
ARG O 105
GLN O  85
 None
 0.98A 4rtbA-6c66O:
undetectable		 4rtbA-6c66O:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6co7 PREDICTED PROTEIN

(Nematostella
vectensis) 		no annotation 3 GLU A 601
ARG A 597
GLN A 474
 None
 0.90A 4rtbA-6co7A:
undetectable		 4rtbA-6co7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d1q RNA
PYROPHOSPHOHYDROLASE

(Escherichia
coli) 		no annotation 3 GLU B  53
ARG B  52
GLN B  95
 None
 0.94A 4rtbA-6d1qB:
undetectable		 4rtbA-6d1qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1

(Homo sapiens) 		no annotation 3 GLU A1353
ARG A1357
GLN A1266
 None
 0.97A 4rtbA-6f9nA:
undetectable		 4rtbA-6f9nA:
undetectable