SIMILAR PATTERNS OF AMINO ACIDS FOR 4R38_D_RBFD201_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ais PROTEIN
(TRANSCRIPTION
INITIATION FACTOR
IIB)

(Pyrococcus
woesei) 		PF00382
(TFIIB) 		4 LEU B1289
VAL B1297
LEU B1261
ILE B1295
 None
 0.86A 4r38D-1aisB:
undetectable		 4r38D-1aisB:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cii COLICIN IA

(Escherichia
coli) 		PF01024
(Colicin)
PF11504
(Colicin_Ia) 		4 THR A 608
ILE A 575
LEU A 591
LEU A 539
 None
 0.82A 4r38D-1ciiA:
0.0		 4r38D-1ciiA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cwp COAT PROTEIN

(Cowpea
chlorotic
mottle virus) 		PF01318
(Bromo_coat) 		4 ILE A  70
LEU A 147
LEU A 154
ILE A 145
 None
 0.83A 4r38D-1cwpA:
0.0		 4r38D-1cwpA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dcq PYK2-ASSOCIATED
PROTEIN BETA

(Mus musculus) 		PF01412
(ArfGap)
PF12796
(Ank_2) 		4 ILE A 387
LEU A 378
ILE A 404
PHE A 434
 None
 0.89A 4r38D-1dcqA:
0.0		 4r38D-1dcqA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dy2 COLLAGEN ALPHA1(XV)
CHAIN

(Mus musculus) 		PF06482
(Endostatin) 		5 ILE A 246
VAL A 150
LEU A 151
ILE A 170
PHE A 121
 None
 1.34A 4r38D-1dy2A:
undetectable		 4r38D-1dy2A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e0t PYRUVATE KINASE

(Escherichia
coli) 		PF00224
(PK)
PF02887
(PK_C) 		5 THR A  95
VAL A 163
LEU A 160
ILE A 165
PHE A  93
 None
 1.17A 4r38D-1e0tA:
0.0		 4r38D-1e0tA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e59 PHOSPHOGLYCERATE
MUTASE

(Escherichia
coli) 		PF00300
(His_Phos_1) 		4 LEU A   7
VAL A  69
LEU A  66
ILE A 179
 None
 0.87A 4r38D-1e59A:
0.0		 4r38D-1e59A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1efp PROTEIN (ELECTRON
TRANSFER
FLAVOPROTEIN)

(Paracoccus
denitrificans) 		PF00766
(ETF_alpha)
PF01012
(ETF) 		4 LEU A 111
VAL A  26
LEU A  29
ILE A 117
 None
 0.81A 4r38D-1efpA:
0.0		 4r38D-1efpA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1egz ENDOGLUCANASE Z

(Dickeya
chrysanthemi) 		PF00150
(Cellulase) 		4 ILE A 130
LEU A 216
LEU A 162
ILE A  12
 None
 0.80A 4r38D-1egzA:
undetectable		 4r38D-1egzA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ems NIT-FRAGILE
HISTIDINE TRIAD
FUSION PROTEIN

(Caenorhabditis
elegans) 		PF00795
(CN_hydrolase)
PF01230
(HIT) 		4 LEU A  94
LEU A 166
ILE A 114
PHE A 191
 None
None
None
NA  A 457 ( 4.7A)
 0.89A 4r38D-1emsA:
0.0		 4r38D-1emsA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f76 DIHYDROOROTATE
DEHYDROGENASE
(QUINONE)

(Escherichia
coli) 		PF01180
(DHO_dh) 		4 ILE A 293
LEU A  74
LEU A  58
ILE A 329
 None
 0.87A 4r38D-1f76A:
undetectable		 4r38D-1f76A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f97 JUNCTION ADHESION
MOLECULE

(Mus musculus) 		PF07686
(V-set)
PF13927
(Ig_3) 		4 VAL A  37
LEU A 125
ILE A  45
PHE A  63
 None
 0.88A 4r38D-1f97A:
undetectable		 4r38D-1f97A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fx2 RECEPTOR-TYPE
ADENYLATE CYCLASE
GRESAG 4.1

(Trypanosoma
brucei) 		PF00211
(Guanylate_cyc) 		4 THR A 901
VAL A1083
LEU A1103
ILE A1081
 None
 0.88A 4r38D-1fx2A:
undetectable		 4r38D-1fx2A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g5b SERINE/THREONINE
PROTEIN PHOSPHATASE

(Escherichia
virus Lambda) 		PF00149
(Metallophos) 		4 ILE A 125
LEU A  44
LEU A 128
ILE A  15
 None
 0.88A 4r38D-1g5bA:
undetectable		 4r38D-1g5bA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gr3 COLLAGEN X

(Homo sapiens) 		PF00386
(C1q) 		4 ILE A 569
VAL A 621
LEU A 614
ILE A 642
 None
 0.88A 4r38D-1gr3A:
undetectable		 4r38D-1gr3A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gvz KALLIKREIN-1E2

(Equus caballus) 		PF00089
(Trypsin) 		4 ILE A 242
VAL A  85
LEU A 108
ILE A  66
 ACT  A1250 ( 4.1A)
None
None
None
 0.79A 4r38D-1gvzA:
undetectable		 4r38D-1gvzA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hdi PHOSPHOGLYCERATE
KINASE

(Sus scrofa) 		PF00162
(PGK) 		5 ILE A 252
LEU A 268
LEU A 281
ILE A 279
PHE A 241
 None
 1.14A 4r38D-1hdiA:
undetectable		 4r38D-1hdiA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hyb NICOTINAMIDE
MONONUCLEOTIDE
ADENYLYLTRANSFERASE

(Methanothermobacter
thermautotrophicus) 		PF01467
(CTP_transf_like) 		4 ILE A  68
VAL A  56
LEU A  59
ILE A  37
 None
 0.84A 4r38D-1hybA:
undetectable		 4r38D-1hybA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iip CYCLOPHILIN 40

(Bos taurus) 		PF00160
(Pro_isomerase)
PF13176
(TPR_7) 		4 LEU A 162
VAL A 152
LEU A  34
ILE A 134
 None
 0.71A 4r38D-1iipA:
undetectable		 4r38D-1iipA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itz TRANSKETOLASE

(Zea mays) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 LEU A 379
VAL A 471
LEU A 529
ILE A 469
 None
 0.77A 4r38D-1itzA:
undetectable		 4r38D-1itzA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ja9 1,3,6,8-TETRAHYDROXY
NAPHTHALENE
REDUCTASE

(Magnaporthe
grisea) 		PF13561
(adh_short_C2) 		4 LEU A 161
VAL A 259
LEU A 262
ILE A 206
 None
 0.85A 4r38D-1ja9A:
undetectable		 4r38D-1ja9A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jfl ASPARTATE RACEMASE

(Pyrococcus
horikoshii) 		PF01177
(Asp_Glu_race) 		4 ILE A 181
VAL A 197
LEU A 175
ILE A 159
 None
 0.86A 4r38D-1jflA:
undetectable		 4r38D-1jflA:
21.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jnu PHY3 PROTEIN

(Adiantum
capillus-veneris) 		PF13426
(PAS_9) 		4 ASN A 965
LEU A 969
VAL A 979
PHE A1025
 FMN  A1033 (-3.2A)
FMN  A1033 (-4.1A)
FMN  A1033 ( 4.9A)
FMN  A1033 ( 4.6A)
 0.85A 4r38D-1jnuA:
19.4		 4r38D-1jnuA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY

(Bradyrhizobium
japonicum) 		PF08534
(Redoxin) 		4 ILE A 168
LEU A 186
LEU A 172
PHE A 160
 None
 0.87A 4r38D-1kngA:
undetectable		 4r38D-1kngA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ksh ARF-LIKE PROTEIN 2

(Mus musculus) 		PF00025
(Arf) 		4 LEU A  33
LEU A 172
ILE A  88
PHE A  60
 None
 0.88A 4r38D-1kshA:
undetectable		 4r38D-1kshA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ksi COPPER AMINE OXIDASE

(Pisum sativum) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 THR A 618
ILE A 279
VAL A 552
ILE A 499
 None
 0.89A 4r38D-1ksiA:
undetectable		 4r38D-1ksiA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lhu SEX HORMONE-BINDING
GLOBULIN

(Homo sapiens) 		PF00054
(Laminin_G_1) 		4 ASN A  82
VAL A 112
LEU A 124
ILE A  78
 EST  A 301 (-3.9A)
None
None
None
 0.81A 4r38D-1lhuA:
undetectable		 4r38D-1lhuA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lq2 BETA-D-GLUCAN
GLUCOHYDROLASE
ISOENZYME EXO1

(Hordeum vulgare) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C) 		4 LEU A 267
VAL A 282
LEU A 312
ILE A 251
 None
 0.85A 4r38D-1lq2A:
undetectable		 4r38D-1lq2A:
13.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1n9l PUTATIVE BLUE LIGHT
RECEPTOR

(Chlamydomonas
reinhardtii) 		PF13426
(PAS_9) 		4 ASN A  56
LEU A  60
VAL A  70
PHE A 116
 FMN  A 500 (-2.9A)
FMN  A 500 (-4.3A)
FMN  A 500 (-4.3A)
FMN  A 500 (-4.8A)
 0.60A 4r38D-1n9lA:
8.1		 4r38D-1n9lA:
38.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nhc POLYGALACTURONASE I

(Aspergillus
niger) 		PF00295
(Glyco_hydro_28) 		4 ILE A 190
VAL A 261
LEU A 231
ILE A 281
 None
 0.86A 4r38D-1nhcA:
undetectable		 4r38D-1nhcA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nwa PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA

(Mycobacterium
tuberculosis) 		PF01625
(PMSR) 		4 VAL A  54
LEU A   9
ILE A  56
PHE A  73
 None
 0.88A 4r38D-1nwaA:
undetectable		 4r38D-1nwaA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1olt OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE

(Escherichia
coli) 		PF04055
(Radical_SAM)
PF06969
(HemN_C) 		4 ASN A 207
LEU A 195
LEU A 210
PHE A 290
 None
 0.86A 4r38D-1oltA:
undetectable		 4r38D-1oltA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1olx 2-OXOISOVALERATE
DEHYDROGENASE BETA
SUBUNIT

(Homo sapiens) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 ILE B 257
LEU B 276
VAL B 295
ILE B 307
 None
 0.78A 4r38D-1olxB:
undetectable		 4r38D-1olxB:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1or4 HEME-BASED
AEROTACTIC
TRANSDUCER HEMAT

(Bacillus
subtilis) 		PF11563
(Protoglobin) 		5 ILE A 100
LEU A  79
VAL A  89
LEU A  92
ILE A  83
 None
HEM  A 180 (-4.1A)
None
CYN  A 181 (-3.5A)
None
 1.21A 4r38D-1or4A:
undetectable		 4r38D-1or4A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p3c GLUTAMYL-ENDOPEPTIDA
SE

(Bacillus
intermedius) 		PF00089
(Trypsin) 		4 ILE A  22
VAL A 100
LEU A  43
ILE A 209
 None
 0.88A 4r38D-1p3cA:
undetectable		 4r38D-1p3cA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p74 SHIKIMATE
5-DEHYDROGENASE

(Haemophilus
influenzae) 		PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		4 LEU A 178
VAL A 146
LEU A 123
ILE A 176
 None
 0.89A 4r38D-1p74A:
undetectable		 4r38D-1p74A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1psz PROTEIN (SURFACE
ANTIGEN PSAA)

(Streptococcus
pneumoniae) 		PF01297
(ZnuA) 		5 THR A  38
ILE A 154
VAL A 122
ILE A  90
PHE A  86
 None
 1.44A 4r38D-1pszA:
undetectable		 4r38D-1pszA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qhb HALOPEROXIDASE

(Corallina
officinalis) 		PF01569
(PAP2) 		4 ILE A 543
VAL A 220
LEU A 223
ILE A 185
 None
 0.86A 4r38D-1qhbA:
undetectable		 4r38D-1qhbA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qxy METHIONYL
AMINOPEPTIDASE

(Staphylococcus
aureus) 		PF00557
(Peptidase_M24) 		4 ILE A   2
VAL A 137
LEU A 193
ILE A 146
 None
 0.78A 4r38D-1qxyA:
1.1		 4r38D-1qxyA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qyi HYPOTHETICAL PROTEIN

(Staphylococcus
aureus) 		PF13242
(Hydrolase_like) 		5 ILE A  83
LEU A 128
LEU A  89
ILE A  92
PHE A  82
 None
 1.44A 4r38D-1qyiA:
undetectable		 4r38D-1qyiA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rt8 FIMBRIN

(Schizosaccharomyces
pombe) 		PF00307
(CH) 		5 ILE A 229
LEU A 220
VAL A 193
LEU A 155
ILE A 213
 None
 1.36A 4r38D-1rt8A:
undetectable		 4r38D-1rt8A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sj5 CONSERVED
HYPOTHETICAL PROTEIN
TM0160

(Thermotoga
maritima) 		PF02577
(DNase-RNase) 		4 ILE A  77
LEU A 106
LEU A  89
ILE A  91
 None
 0.88A 4r38D-1sj5A:
undetectable		 4r38D-1sj5A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sw6 REGULATORY PROTEIN
SWI6

(Saccharomyces
cerevisiae) 		PF00023
(Ank)
PF13857
(Ank_5) 		4 ILE A 498
LEU A 480
LEU A 489
ILE A 485
 None
 0.78A 4r38D-1sw6A:
undetectable		 4r38D-1sw6A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t1u CHOLINE
O-ACETYLTRANSFERASE

(Rattus
norvegicus) 		PF00755
(Carn_acyltransf) 		4 THR A 477
LEU A 438
VAL A 443
LEU A 442
 None
 0.88A 4r38D-1t1uA:
undetectable		 4r38D-1t1uA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tll NITRIC-OXIDE
SYNTHASE, BRAIN

(Rattus
norvegicus) 		PF00175
(NAD_binding_1)
PF00258
(Flavodoxin_1)
PF00667
(FAD_binding_1) 		4 LEU A1359
VAL A1335
LEU A1339
ILE A1346
 None
 0.81A 4r38D-1tllA:
undetectable		 4r38D-1tllA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tve HOMOSERINE
DEHYDROGENASE

(Saccharomyces
cerevisiae) 		PF00742
(Homoserine_dh)
PF03447
(NAD_binding_3) 		4 ASN A 190
VAL A 284
LEU A 285
PHE A 194
 None
 0.84A 4r38D-1tveA:
undetectable		 4r38D-1tveA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tvp CELLULASE

(Pseudoalteromonas
haloplanktis) 		PF00150
(Cellulase) 		4 ILE A 132
LEU A 218
LEU A 164
ILE A  12
 None
 0.87A 4r38D-1tvpA:
undetectable		 4r38D-1tvpA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ua4 ADP-DEPENDENT
GLUCOKINASE

(Pyrococcus
furiosus) 		PF04587
(ADP_PFK_GK) 		4 ASN A  30
LEU A 237
LEU A 265
ILE A 279
 GLC  A1457 (-4.2A)
None
None
None
 0.81A 4r38D-1ua4A:
undetectable		 4r38D-1ua4A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ue8 367AA LONG
HYPOTHETICAL
CYTOCHROME P450

(Sulfurisphaera
tokodaii) 		PF00067
(p450) 		4 ILE A 349
VAL A 361
LEU A 360
ILE A 343
 None
 0.88A 4r38D-1ue8A:
undetectable		 4r38D-1ue8A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uf2 OUTER CAPSID PROTEIN
P8

(Rice dwarf
virus) 		no annotation 4 ILE P 400
LEU P 410
LEU P 352
ILE P  72
 None
 0.70A 4r38D-1uf2P:
1.5		 4r38D-1uf2P:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ujv MEMBRANE ASSOCIATED
GUANYLATE KINASE
INVERTED-2 (MAGI-2)

(Homo sapiens) 		PF00595
(PDZ) 		4 ILE A  79
VAL A  71
LEU A  74
ILE A  27
 None
 0.87A 4r38D-1ujvA:
undetectable		 4r38D-1ujvA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus) 		PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36) 		4 THR A 581
LEU A 605
LEU A 669
ILE A 641
 None
 0.80A 4r38D-1v7vA:
undetectable		 4r38D-1v7vA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vgm 378AA LONG
HYPOTHETICAL CITRATE
SYNTHASE

(Sulfurisphaera
tokodaii) 		PF00285
(Citrate_synt) 		5 ILE A  69
LEU A 104
VAL A 340
LEU A 344
ILE A 207
 None
 1.44A 4r38D-1vgmA:
undetectable		 4r38D-1vgmA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpx PROTEIN
(TRANSALDOLASE (EC
2.2.1.2))

(Thermotoga
maritima) 		PF00923
(TAL_FSA) 		4 THR A  27
ILE A 161
LEU A  73
PHE A   4
 None
 0.87A 4r38D-1vpxA:
undetectable		 4r38D-1vpxA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vzo RIBOSOMAL PROTEIN S6
KINASE ALPHA 5

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 134
LEU A 180
LEU A 193
ILE A 178
 None
 0.85A 4r38D-1vzoA:
undetectable		 4r38D-1vzoA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w85 PYRUVATE
DEHYDROGENASE E1
COMPONENT, BETA
SUBUNIT

(Geobacillus
stearothermophilus) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 ILE B 192
VAL B 136
LEU B 142
ILE B  93
 None
 0.74A 4r38D-1w85B:
0.8		 4r38D-1w85B:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wba WINGED BEAN ALBUMIN
1

(Psophocarpus
tetragonolobus) 		PF00197
(Kunitz_legume) 		5 ILE A  80
VAL A  47
LEU A 156
ILE A 146
PHE A 118
 None
 1.39A 4r38D-1wbaA:
undetectable		 4r38D-1wbaA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x7p RRNA
METHYLTRANSFERASE

(Streptomyces
viridochromogenes) 		PF00588
(SpoU_methylase) 		4 ILE A 205
LEU A 229
ILE A 270
PHE A 126
 None
 0.86A 4r38D-1x7pA:
undetectable		 4r38D-1x7pA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xbz 3-KETO-L-GULONATE
6-PHOSPHATE
DECARBOXYLASE

(Escherichia
coli) 		PF00215
(OMPdecase) 		4 LEU A  53
VAL A  34
LEU A  10
ILE A  32
 None
 0.87A 4r38D-1xbzA:
undetectable		 4r38D-1xbzA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xe1 HYPOTHETICAL PROTEIN
PF0907

(Pyrococcus
furiosus) 		PF14578
(GTP_EFTU_D4) 		4 ILE A  20
VAL A  29
LEU A 103
ILE A  43
 None
 0.87A 4r38D-1xe1A:
undetectable		 4r38D-1xe1A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE

(Archaeoglobus
fulgidus) 		PF05362
(Lon_C) 		4 ILE A 469
VAL A 543
LEU A 537
ILE A 592
 None
 0.87A 4r38D-1z0vA:
undetectable		 4r38D-1z0vA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z63 HELICASE OF THE
SNF2/RAD54 FAMILY

(Sulfolobus
solfataricus) 		PF00176
(SNF2_N)
PF00271
(Helicase_C) 		4 ILE A 538
VAL A 578
ILE A 574
PHE A 523
 None
 0.83A 4r38D-1z63A:
undetectable		 4r38D-1z63A:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zbd RABPHILIN-3A

(Rattus
norvegicus) 		PF00071
(Ras) 		4 ILE A  71
LEU A  39
LEU A 179
ILE A  99
 None
 0.80A 4r38D-1zbdA:
undetectable		 4r38D-1zbdA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zyb TRANSCRIPTION
REGULATOR, CRP
FAMILY

(Bacteroides
thetaiotaomicron) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 ILE A 124
VAL A 115
LEU A 119
ILE A 110
 None
 0.88A 4r38D-1zybA:
undetectable		 4r38D-1zybA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a7n L(+)-MANDELATE
DEHYDROGENASE

(Pseudomonas
putida;
Spinacia
oleracea) 		PF01070
(FMN_dh) 		4 THR A 148
LEU A 107
VAL A 154
LEU A 153
 None
 0.83A 4r38D-2a7nA:
undetectable		 4r38D-2a7nA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aky ADENYLATE KINASE

(Saccharomyces
cerevisiae) 		PF00406
(ADK)
PF05191
(ADK_lid) 		4 THR A 110
ILE A   5
LEU A  88
ILE A  72
 None
 0.81A 4r38D-2akyA:
undetectable		 4r38D-2akyA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2anc GUANYLATE KINASE

(Escherichia
coli) 		PF00625
(Guanylate_kin) 		4 LEU A 166
LEU A 179
ILE A 121
PHE A 172
 None
 0.72A 4r38D-2ancA:
undetectable		 4r38D-2ancA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2anu HYPOTHETICAL PROTEIN
TM0559

(Thermotoga
maritima) 		no annotation 4 THR A  51
ILE A  46
LEU A 104
VAL A 122
 None
 0.88A 4r38D-2anuA:
undetectable		 4r38D-2anuA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2atx SMALL GTP BINDING
PROTEIN TC10

(Homo sapiens) 		PF00071
(Ras) 		4 LEU A 125
VAL A 112
LEU A 115
ILE A  94
 None
 0.87A 4r38D-2atxA:
undetectable		 4r38D-2atxA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5e PROTEIN
DISULFIDE-ISOMERASE

(Saccharomyces
cerevisiae) 		PF00085
(Thioredoxin)
PF13848
(Thioredoxin_6) 		4 ILE A  88
LEU A  53
ILE A 131
PHE A  56
 None
 0.68A 4r38D-2b5eA:
undetectable		 4r38D-2b5eA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bbk METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans) 		PF06433
(Me-amine-dh_H) 		5 ILE H 215
LEU H 336
VAL H 300
LEU H 284
ILE H 320
 None
 1.39A 4r38D-2bbkH:
2.1		 4r38D-2bbkH:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bfu COWPEA MOSAIC VIRUS,
SMALL (S) SUBUNIT

(Cowpea mosaic
virus) 		PF02248
(Como_SCP) 		4 THR S  19
ILE S  16
LEU S  74
ILE S 110
 None
 0.87A 4r38D-2bfuS:
1.3		 4r38D-2bfuS:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2btv PROTEIN (VP3 CORE
PROTEIN)

(Bluetongue
virus) 		PF01700
(Orbi_VP3) 		4 THR A 331
ILE A 326
LEU A 576
ILE A 343
 None
 0.88A 4r38D-2btvA:
undetectable		 4r38D-2btvA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c94 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE

(Mycobacterium
tuberculosis) 		PF00885
(DMRL_synthase) 		4 LEU A  79
VAL A  97
LEU A 101
ILE A  62
 None
 0.79A 4r38D-2c94A:
undetectable		 4r38D-2c94A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cr5 REPRODUCTION 8

(Mus musculus) 		PF00789
(UBX) 		4 ASN A  94
LEU A  74
VAL A  26
ILE A  87
 None
 0.83A 4r38D-2cr5A:
undetectable		 4r38D-2cr5A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cwa SINGLE-STRAND
BINDING PROTEIN

(Thermus
thermophilus) 		PF00436
(SSB) 		4 ILE A 197
LEU A  97
ILE A  99
PHE A 132
 None
 0.88A 4r38D-2cwaA:
undetectable		 4r38D-2cwaA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2czd OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Pyrococcus
horikoshii) 		PF00215
(OMPdecase) 		4 ILE A  63
LEU A  99
VAL A  84
LEU A  60
 None
 0.84A 4r38D-2czdA:
undetectable		 4r38D-2czdA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1q LUCIFERIN
4-MONOOXYGENASE

(Luciola
cruciata) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 ILE A  80
LEU A 212
LEU A  98
ILE A 217
 None
 0.88A 4r38D-2d1qA:
undetectable		 4r38D-2d1qA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1y HYPOTHETICAL PROTEIN
TT0321

(Thermus
thermophilus) 		PF13561
(adh_short_C2) 		5 ILE A  22
ASN A  83
VAL A 174
ILE A 172
PHE A  26
 None
 1.31A 4r38D-2d1yA:
undetectable		 4r38D-2d1yA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dwc 433AA LONG
HYPOTHETICAL
PHOSPHORIBOSYLGLYCIN
AMIDE FORMYL
TRANSFERASE

(Pyrococcus
horikoshii) 		PF02222
(ATP-grasp) 		5 LEU A 324
VAL A 216
LEU A 316
ILE A 326
PHE A 314
 None
 1.36A 4r38D-2dwcA:
undetectable		 4r38D-2dwcA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ewm (S)-1-PHENYLETHANOL
DEHYDROGENASE

(Azoarcus) 		PF13561
(adh_short_C2) 		5 ILE A  23
ASN A  88
VAL A 179
ILE A 177
PHE A  27
 None
 1.38A 4r38D-2ewmA:
undetectable		 4r38D-2ewmA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6x (S)-3-O-GERANYLGERAN
YLGLYCERYL PHOSPHATE
SYNTHASE

(Archaeoglobus
fulgidus) 		PF01884
(PcrB) 		4 THR A1229
ILE A1213
LEU A1012
ILE A1022
 None
1GP  A3001 ( 4.6A)
None
None
 0.75A 4r38D-2f6xA:
undetectable		 4r38D-2f6xA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fiq PUTATIVE TAGATOSE
6-PHOSPHATE KINASE 1

(Escherichia
coli) 		PF08013
(Tagatose_6_P_K) 		4 ILE A 407
LEU A  42
LEU A  31
ILE A  82
 None
 0.77A 4r38D-2fiqA:
undetectable		 4r38D-2fiqA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g5g PUTATIVE LIPOPROTEIN

(Campylobacter
jejuni) 		PF04187
(Cofac_haem_bdg) 		5 THR X 221
ILE X 240
LEU X 215
LEU X  36
ILE X  60
 None
 1.31A 4r38D-2g5gX:
undetectable		 4r38D-2g5gX:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gf9 RAS-RELATED PROTEIN
RAB-3D

(Homo sapiens) 		PF00071
(Ras) 		5 ILE A  71
LEU A  39
VAL A 175
LEU A 179
PHE A  23
 None
 1.18A 4r38D-2gf9A:
undetectable		 4r38D-2gf9A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h01 2-CYS PEROXIREDOXIN

(Plasmodium
yoelii) 		PF00578
(AhpC-TSA)
PF10417
(1-cysPrx_C) 		4 ILE A 147
LEU A  22
ILE A  97
PHE A 121
 None
 0.86A 4r38D-2h01A:
undetectable		 4r38D-2h01A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h5g DELTA
1-PYRROLINE-5-CARBOX
YLATE SYNTHETASE

(Homo sapiens) 		PF00171
(Aldedh) 		4 ILE A 688
LEU A 624
LEU A 618
ILE A 633
 None
 0.82A 4r38D-2h5gA:
undetectable		 4r38D-2h5gA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h6e D-ARABINOSE
1-DEHYDROGENASE

(Sulfolobus
solfataricus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 127
VAL A  88
LEU A 134
ILE A  33
 None
 0.82A 4r38D-2h6eA:
undetectable		 4r38D-2h6eA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h84 STEELY1

(Dictyostelium
discoideum) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 THR A3057
VAL A3046
LEU A3049
ILE A3128
 None
 0.88A 4r38D-2h84A:
undetectable		 4r38D-2h84A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hjh NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2

(Saccharomyces
cerevisiae) 		PF02146
(SIR2)
PF04574
(DUF592) 		4 ILE A 244
LEU A 467
LEU A 251
ILE A 257
 None
 0.80A 4r38D-2hjhA:
undetectable		 4r38D-2hjhA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ho5 OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY

(Streptococcus
pneumoniae) 		PF01408
(GFO_IDH_MocA) 		5 ILE A  90
VAL A  29
LEU A  28
ILE A  49
PHE A  16
 None
 1.45A 4r38D-2ho5A:
undetectable		 4r38D-2ho5A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hsn GU4 NUCLEIC-BINDING
PROTEIN 1

(Saccharomyces
cerevisiae) 		no annotation 4 ILE B 104
LEU B 110
ILE B  15
PHE B  73
 None
 0.87A 4r38D-2hsnB:
undetectable		 4r38D-2hsnB:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hz7 GLUTAMINYL-TRNA
SYNTHETASE

(Deinococcus
radiodurans) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		5 LEU A 444
VAL A 468
LEU A 462
ILE A 476
PHE A 481
 None
 1.47A 4r38D-2hz7A:
undetectable		 4r38D-2hz7A:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i32 ANTI-SILENCING
FACTOR 1 PARALOG A

(Homo sapiens) 		PF04729
(ASF1_hist_chap) 		4 THR A 147
ILE A 151
ILE A  43
PHE A 106
 None
 0.87A 4r38D-2i32A:
undetectable		 4r38D-2i32A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iu5 HTH-TYPE DHAKLM
OPERON
TRANSCRIPTIONAL
ACTIVATOR DHAS

(Lactococcus
lactis) 		PF00440
(TetR_N) 		4 ILE A 119
LEU A  82
VAL A 168
LEU A 171
 None
 0.77A 4r38D-2iu5A:
undetectable		 4r38D-2iu5A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7n RNA-DEPENDENT RNA
POLYMERASE

(Neurospora
crassa) 		PF05183
(RdRP) 		5 ILE A 912
ASN A 795
VAL A 801
LEU A 802
ILE A 971
 None
 1.23A 4r38D-2j7nA:
undetectable		 4r38D-2j7nA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2je1 ACIDIC LEUCINE-RICH
NUCLEAR
PHOSPHOPROTEIN 32
FAMILY MEMBER A

(Homo sapiens) 		PF14580
(LRR_9) 		4 LEU A  95
VAL A 135
LEU A 139
ILE A 106
 None
 0.87A 4r38D-2je1A:
undetectable		 4r38D-2je1A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgq TRIOSEPHOSPHATE
ISOMERASE

(Helicobacter
pylori) 		PF00121
(TIM) 		5 ILE A 118
LEU A 140
LEU A 149
ILE A 185
PHE A 108
 None
 1.30A 4r38D-2jgqA:
undetectable		 4r38D-2jgqA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jwy UNCHARACTERIZED
LIPOPROTEIN YAJI

(Escherichia
coli) 		PF11622
(DUF3251) 		5 ILE A 104
VAL A 144
LEU A 147
ILE A  71
PHE A 149
 None
 1.20A 4r38D-2jwyA:
undetectable		 4r38D-2jwyA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kxp F-ACTIN-CAPPING
PROTEIN SUBUNIT
ALPHA-1
F-ACTIN-CAPPING
PROTEIN SUBUNIT BETA
ISOFORMS 1 AND 2

(Gallus gallus) 		PF01115
(F_actin_cap_B)
PF01267
(F-actin_cap_A) 		5 ILE B 549
LEU A 192
VAL B 540
LEU B 543
ILE A 194
 None
 1.38A 4r38D-2kxpB:
1.4		 4r38D-2kxpB:
19.48